20 results on '"Ren, Yi"'
Search Results
2. Effect of tanshinone IIA for myocardial ischemia/reperfusion injury in animal model: preclinical evidence and possible mechanisms
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Peng-Chong Zhu, Jiayi Shen, Ren-Yi Qian, Jian Xu, Chong Liu, Wu-Ming Hu, Ying Zhang, and Ling-Chun Lv
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tanshinone IIA ,myocardial ischemia/reperfusion injury ,preclinical evidence ,possible mechanisms ,meta-analysis ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Introduction: Tanshinone IIA (Tan IIA), the major active lipophilic ingredient of Radix Salviae Miltiorrhizae, exerts various therapeutic effects on the cardiovascular system. We aimed to identify the preclinical evidence and possible mechanisms of Tan IIA as a cardioprotective agent in the treatment of myocardial ischemia/reperfusion injury.Methods: The study quality scores of twenty-eight eligible studies and data analyses were separately assessed using the CAMARADES 10-item checklist and Rev-Man 5.3 software.Results: The study quality score ranged from 3/10 to 7/10 points. The present study provided preliminary preclinical evidence that Tan IIA could significantly decrease the myocardial infarct size, cardiac enzyme activity and troponin levels compared with those in the control group (p < 0.05).Discussion: Tan IIA alleviated myocardial I/R injury via antioxidant, anti-inflammatory, anti-apoptosis mechanisms and improved circulation and energy metabolism. Thus, Tan IIA is a promising cardioprotective agent for the treatment of myocardial ischemia/reperfusion injury and should be further investigated in clinical trials.
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- 2023
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3. Distal tibial tubercle osteotomy can lessen change in patellar height post medial opening wedge high tibial osteotomy? A systematic review and meta-analysis
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Ren, Yi-Ming, Tian, Meng-Qiang, Duan, Yuan-Hui, Sun, Yun-Bo, Yang, Tao, and Hou, Wei-Yu
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- 2022
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4. Gabapentin has Longer-Term Efficacy for the Treatment of Chronic Pelvic Pain in Women: A Systematic Review and Pilot Meta-analysis
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Fan, Xiu-Mei, Ren, Yi-Feng, Fu, Xi, Wu, Hao, Ye, Xin, Jiang, Yi-Fang, and You, Feng-Ming
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- 2021
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5. Does Inhaled Methoxyflurane Implement Fast and Efficient Pain Management in Trauma Patients? A Systematic Review and Meta-Analysis
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Liu, Hong, Fu, Xi, Ren, Yi-Feng, Tan, Shi-Yan, Xiang, Si-Rui, Zheng, Chuan, You, Feng-Ming, Shi, Wei, and Li, Lin-Jiong
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- 2021
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6. A Meta-Analysis Showing the Quantitative Evidence Base of Preemptive Pregabalin for Postoperative Pain from Cancer-Related Surgery.
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Wang, Qian, Dong, Jing, Ye, Xin, and Ren, Yi-Feng
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CANCER pain ,POSTOPERATIVE pain ,PREGABALIN ,ANALGESIA ,SURGERY ,DATABASE searching - Abstract
Background and Objectives: As an adjunct to postoperative multimodal analgesic regimens, pregabalin has been reported in reducing postoperative acute pain and opioid consumption. However, there is only a small amount of evidence for preemptive pregabalin in patients undergoing cancer-related surgery. This systematic review was conducted to integrate high-quality evidence to evaluate the preemptive analgesic effects of pregabalin in cancer-related surgery. Materials and Methods: Seven electronic databases were searched in a combination of subject terms and free words. Efficacy and safety of preemptive pregabalin on postoperative pain for cancer-related surgery were evaluated by assessing resting and dynamic pain scores postoperatively, cumulative morphine equivalent consumption, time to first analgesic request, hemodynamic parameters, and the safety indicators. Results: Thirteen trials were incorporated for quantitative synthesis. The pooled results showed administration of pregabalin preoperatively is clinically significant for improving resting (weighted mean difference (WMD), −1.53 cm; 95% CI, −2.30 to −0.77) and dynamic (WMD, −1.16 cm; 95% CI, −2.22 to −0.11) pain severity scores at 2 h postoperatively and prolonging time to first analgesic request (WMD, 2.28 h; 95% CI, 0.79 to 3.77) in cancer-related surgery. Preemptive pregabalin was also statistically effective in some other pain indicators but would increase the risk of pregabalin-related side effects after surgery. Conclusions: Our findings do not support the administration of pregabalin in doses larger than 300 mg when put in cancer-related surgery. Taken together, more high-quality research particularly focused on the optimal dosages and timing of pregabalin in cancer-related surgery is needed in the future to establish stronger evidence for therapeutic effects. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer
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Yuan, Xin, Zhang, An Zhi, Ren, Yi Lin, Wang, Xue Li, Jiang, Chen Hao, Yang, Lan, Liu, Chun Xia, Liang, Wei Hua, Pang, Li Juan, Gu, Wen Yi, Li, Feng, and Hu, Jian Ming
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Male ,Esophageal Neoplasms ,cytokine-induced killer cells ,Antineoplastic Agents ,Dendritic Cells ,Adaptive Immunity ,Middle Aged ,Combined Modality Therapy ,meta-analysis ,Cytokine-Induced Killer Cells ,Treatment Outcome ,Humans ,Female ,dendritic cells ,esophageal cancer ,immunotherapy ,Systematic Review and Meta-Analysis ,Research Article ,Aged ,Randomized Controlled Trials as Topic - Abstract
Objectives: This meta-analysis was designed to systematically evaluate whether autologous cytokine-induced killer cells (CIK) or dendritic cells and cytokine-induced killer cells (DC-CIK) immunotherapy combined with chemotherapy can improve the therapeutic effect and safety of chemotherapy in esophageal cancer (EC). Materials and methods: Randomized controlled trials (RCTs) were electronically searched databases including CNKI, WanFang, WeiPu, CBMDisc, PubMed, Web of Science, EMbase, the Cochrane Library, and Clinical Trials. The databases were searched for articles published until June 2019. Two researchers independently screened the literature, extracted data, and evaluated the quality of the included literature. Meta-analysis was performed using RevMan5.3. Results: Seventeen studies (1416 participants) were included. The differences between CIK/DC-CIK combination chemotherapy and chemotherapy alone were significant. The results displayed that the number of CD3+, CD4+, CD4+/CD8+, and NK cells was significantly increased after 1 to 2 weeks of treatment with CIK/DC-CIK cells in the treatment group (all P
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- 2021
8. Is Auricular Stimulation Actually Useful in Reducing Preoperative Anxiety?
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Dong, Jing, Liao, Yan-Chun, Chen, Xiang, Ye, Xin, and Ren, Yi-Feng
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ACUPUNCTURE points ,ACUPRESSURE ,ANXIETY ,STATE-Trait Anxiety Inventory - Abstract
Keywords: anxiety; auricular stimulation; meta-analysis; minimal clinically important difference; preoperative EN anxiety auricular stimulation meta-analysis minimal clinically important difference preoperative 1 4 4 05/26/22 20220415 NES 220415 Introduction The majority of patients commonly suffer from varying levels of exposure to physical and psychological stress during the perioperative period (before and after surgery). 10.1213/01.ane.0000242531.12722.fd 16 Luo, L, Dai, Q, Mo, Y, Yan, Y, Qian, M, Zhuang, X,The effect of auricular acupressure on preoperative anxiety in patients undergoing gynecological surgery. Discussion It should be pointed out that the STAI scale was employed in most included trials in the review by Usichenko et al. ([7]), however, we are curious about why effect-sizes were summarized as standard mean difference (SMD) rather than weighted mean difference (WMD). MCID is defined as the smallest change that is meaningful to patients and is considered the threshold needed to achieve treatment efficacy ([12]). [Extracted from the article]
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- 2022
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9. Arthroscopic labral debridement versus labral repair for patients with femoroacetabular impingement
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Wu, Zhan-Xiong, Ren, Wen-Xia, Ren, Yi-Ming, and Tian, Meng-Qiang
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Adult ,Male ,acetabular labrum ,Fibrocartilage ,Middle Aged ,meta-analysis ,hip arthroscopic surgery ,Arthroscopy ,Postoperative Complications ,systematic review ,Debridement ,Patient Satisfaction ,Femoracetabular Impingement ,Humans ,Female ,Systematic Review and Meta-Analysis ,Research Article ,femoroacetabular impingement - Abstract
Objective: Femoroacetabular impingement (FAI) is a common cause of hip pain and even tearing of the acetabular labrum in young adults and athletes. Either arthroscopic labral debridement (LD) or labral repair (LR) technique for FAI patients is needed to choose. We conducted this systematic review and meta-analysis to compare the clinical outcomes of arthroscopic LD versus LR intervention. Methods: The five studies were acquired from PubMed, Medline, Embase, and Cochrane Library. The data were extracted by two of the coauthors independently and were analyzed by RevMan5.3. Mean differences (MDs), odds ratios (ORs), and 95% confidence intervals (CIs) were calculated. Cochrane Collaboration's Risk of Bias Tool and Newcastle–Ottawa Scale were used to assess risk of bias. Results: Four observational studies and one prospective randomized study were assessed. The methodological quality of the trials indicated a low to moderate risk of bias. The pooled results of Non-Arthritic Hip Score (NAHS), failure rate of surgeries and complications showed that the differences were not statistically significant between the two interventions. The difference of modified Harris Hip Score (mHHS), the Visual Analogue Scale (VAS) score and satisfaction rate was statistically significant between LD and LR intervention, and LR treatment was more effective. Sensitivity analysis proved the stability of the pooled results and there were too less included articles to verify the publication bias. Conclusions: Hip arthroscopy with either LR or LD is an effective treatment for symptomatic FAI. The difference of mHHS, VAS score, and satisfaction rate was statistically significant between LD and LR intervention, and arthroscopic LR could re-create suction-seal effect, potentially reduce microinstability, which demonstrated a trend toward better clinical efficacy and comparable safety compared with LD. The arthroscopic LR technique is recommended as the optical choice for acetabular labrum tear with FAI.
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- 2020
10. Pain relieving effect of dexmedetomidine in patients undergoing total knee or hip arthroplasty
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Yang, Qi, Ren, Yi, Feng, Bin, and Weng, Xisheng
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Male ,total knee arthroplasty ,Pain, Postoperative ,total hip arthroplasty ,Arthroplasty, Replacement, Hip ,dexmedetomidine ,Analgesics, Non-Narcotic ,Middle Aged ,meta-analysis ,delirium ,Treatment Outcome ,pain management ,Humans ,Female ,Systematic Review And Meta-Analysis ,Arthroplasty, Replacement, Knee ,Research Article ,Aged - Abstract
Background To evaluate the safety and efficacy of dexmedetomidine in patients undergoing total knee and hip arthroplasty for postoperative pain control. Methods An updated systematic review and meta-analysis of randomized controlled trials (RCTs) identified in systematic searches of MEDLINE, EMBASE, Google Scholar, the Cochrane Database and the Chinese SinoMed Database. Results Fourteen RCTs with a total of 1220 patients were included. Overall, dexmedetomidine therapy was associated with significantly decreased pain scores 24 hours after surgery (WMD, −0.36; 95% CI, −0.49 to −0.22; I2 = 90.0%, P
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- 2020
11. Comparison of arthroscopic suture-bridge technique and double-row technique for treating rotator cuff tears
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Ren, Yi-Ming, Zhang, Hong-Bin, Duan, Yuan-Hui, Sun, Yun-Bo, Yang, Tao, and Tian, Meng-Qiang
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suture-bridge ,rotator cuff tear ,Suture Techniques ,Rotator Cuff Injuries ,meta-analysis ,Arthroscopy ,double-row ,systematic review ,Odds Ratio ,Humans ,Range of Motion, Articular ,Systematic Review and Meta-Analysis ,Research Article ,Pain Measurement - Abstract
Background: Rotator cuff tear is a common shoulder disorder in the elderly. Either arthroscopic double-row (DR) or suture-bridge (SB) technique for rotator cuff tear patients is needed to choose. We conducted this systematic review and meta-analysis to compare the clinical outcomes of arthroscopic SB versus DR intervention. Methods: The 7 studies were acquired from PubMed, Medline, Embase, CNKI, Google, and Cochrane Library. The data were extracted by 2 of the co-authors independently and were analyzed by RevMan5.3. Mean differences (MDs), odds ratios (ORs), and 95% confidence intervals (CIs) were calculated. Cochrane Collaboration's Risk of Bias Tool and Newcastle–Ottawa scale were used to assess risk of bias. Results: Seven studies including 1 randomized controlled trial and 6 observational studies were assessed. The methodological quality of the trials ranged from low to moderate. The pooled results of American Shoulder and Elbow Surgeons score, Constant score, visual analog scale score, and range of motion showed that the differences were not statistically significant between the 2 interventions. The difference of University of California at Los Angeles (UCLA) score was statistically significant between SB and DR intervention, and SB treatment was more effective (MD = −0.95, 95% CI = −1.70 to −0.20, P = .01). The difference of re-tear rate was statistically significant and SB treatment achieved better result than DR treatment (OR = 0.31, 95% CI = 0.15–0.64, P = .001). Sensitivity analysis proved the stability of the pooled results and the publication bias was not apparent. Conclusions: Both arthroscopic SB and DR interventions had benefits in rotator cuff tear. SB treatment was more effective in UCLA score and had lower re-tear rate than DR treatment. The arthroscopic SB technique is recommended as the optical choice for rotator cuff tear.
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- 2019
12. Separate double-layer repair versus en masse repair for delaminated rotator cuff tears: a systematic review and meta-analysis.
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Chen, Jia, Zheng, Zhen-Yang, and Ren, Yi-Ming
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ARTHROSCOPY ,CONFIDENCE intervals ,INFORMATION storage & retrieval systems ,MEDICAL databases ,MEDICAL information storage & retrieval systems ,RANGE of motion of joints ,MEDLINE ,META-analysis ,ONLINE information services ,ORTHOPEDIC surgery ,ROTATOR cuff injuries ,SYSTEMATIC reviews ,VISUAL analog scale ,TREATMENT effectiveness ,ODDS ratio - Abstract
Objective: Delaminated rotator cuff tears are a common shoulder disorder in elderly individuals. Either arthroscopic separate double-layer repair (DR) or en masse repair (ER) is used to treat a delaminated rotator cuff tear. We conducted this systematic review and meta-analysis to compare the clinical outcomes of arthroscopic ER versus DR intervention. Methods: Five studies were acquired from PubMed, Medline, Embase, CNKI, Google, and the Cochrane Library. The data were extracted by two of the coauthors independently and were analyzed with RevMan 5.3. Mean differences (MDs), odds ratios (ORs), and 95% confidence intervals (CIs) were calculated. The Cochrane Collaboration's risk of bias tool and Newcastle–Ottawa Scale were used to assess the risk of bias. Results: Five studies, including two randomized controlled trials (RCTs) and three observational studies, were assessed. The methodological quality of the trials ranged from low to high. The pooled results for the Shoulder Rating Scale of the University of California at Los Angeles (UCLA) score, visual analog scale (VAS) score, Constant score, and range of motion (ROM) showed that the outcomes were not statistically significant between the two interventions. The difference in retear rate was not statistically significant (OR = 0.69, 95% CI = 0.36–1.33, P = 0.27). The sensitivity analysis proved the stability of the pooled results, and publication bias was not apparent. Conclusions: Both arthroscopic ER and DR interventions had benefits in delaminated rotator cuff tear treatment. ER and DR treatments were equally effective and had the same retear rate. The arthroscopic DR technique could not be recommended as the optical choice for delaminated rotator cuff tears based on current evidence. [ABSTRACT FROM AUTHOR]
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- 2020
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13. Meta-analysis of the efficacy and safety of structured triglyceride lipid emulsions in parenteral nutrition therapy in China.
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Li, Chao, Ni, Qian, Pei, Yifang, Ren, Yi, and Feng, Yufei
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We performed a meta-analysis of data from recent studies to evaluate the safety and efficacy of parenteral nutrition (PN) with structured triglyceride (STG) lipid emulsions compared to medium-chain triglyceride (MCT)/long-chain triglyceride (LCT) lipid emulsions in Chinese patients. PubMed, Embase, Cochrane Library, China National Knowledge Internet, Wanfang, and VIP were searched for randomized controlled trials comparing STGs with MCTs/LCTs published in English or Chinese between January 1987 and October 2017. Two independent investigators screened and selected studies according to prespecified selection criteria. Data were pooled and analysed using RevMan
® version 5.3. Thirty-two studies comprising 1944 patients were included in the meta-analysis. Compared with MCT/LCT emulsions, STGs resulted in a shorter hospital length of stay (LOS) (weighted mean difference [WMD], −1.65 days; 95% confidence interval [CI]: −2.63, −0.67; P = 0.001) and lower adverse event rates (relative risk, 0.64; 95% CI: 0.48, 0.85; P = 0.002). STGs were associated with a significantly better cumulative nitrogen balance (WMD, 4.04 g/24 h; 95% CI: 3.10, 4.97; P < 0.0001) as well as higher concentrations of pre-albumin (WMD 35.20 mg/L; 95% CI: 26.59, 43.81; P < 0.0001) and albumin (WMD, 1.64 g/L; 95% CI: 1.17, 2.10; P < 0.0001) compared with MCTs/LCTs. In contrast, significantly lower concentrations of plasma triglycerides (WMD, −0.21 mmol/L; 95% CI: −0.30, −0.12; P < 0.0001), total cholesterol (WMD, −0.45 mmol/L; 95% CI: −0.60, −0.29; P < 0.0001), alanine aminotransferase (WMD, −7.68 IU/L; 95% CI: −9.68, −5.68; P < 0.0001) and aspartate aminotransferase (WMD, −10.27 IU/L; 95% CI: −16.05, −4.49; P = 0.0005) were observed in patients receiving STGs compared with MCT/LCTs. STGs were also associated with reduced inflammation and improved immunological function, as reflected by significantly lower C-reactive protein concentrations (WMD, −2.67 mg/L; 95% CI: −4.55, −0.79; P = 0.005) and increased concentrations of IgG (WMD, 2.11 g/L; 95% CI: 0.23, 3.99; P = 0.03), IgA (WMD, 0.21 g/L; 95% CI: 0.14, 0.28; P < 0.0001), CD3+ (WMD, 5.81%; 95% CI: 0.92, 10.70; P = 0.02), and CD4+/CD8+ (WMD, 0.12; 95% CI: 0.00, 0.24; P = 0.04) compared with MCT/LCTs. Administration of STGs was shown to improve hepatic function, nutrition status, and immunological function and reduce inflammation, LOS, and adverse events compared with MCT/LCTs in Chinese patients receiving PN. [ABSTRACT FROM AUTHOR]- Published
- 2019
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14. Efficacy and reliability of active robotic-assisted total knee arthroplasty compared with conventional total knee arthroplasty: a systematic review and meta-analysis.
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Yi Ren, Shiliang Cao, Jinxuan Wu, Xisheng Weng, Bin Feng, Ren, Yi, Cao, Shiliang, Wu, Jinxuan, Weng, Xisheng, and Feng, Bin
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TOTAL knee replacement ,META-analysis ,TOTAL hip replacement ,FIXED effects model - Abstract
Background: In the field of prosthetics, the ultimate goal is to improve the clinical outcome by using a technique that prolongs the longevity of prosthesis. Active robotic-assisted total knee arthroplasty (TKA) is one such technique that is capable of providing accurate implant position and restoring mechanical alignment. Although relevant studies have been carried out, the differences in the efficacy and reliability between active robotic-assisted TKA and conventional arthroplasty have not yet been adequately discussed.Methods: We referenced articles, including randomised controlled trials and comparative retrospective research, from PubMed, Embase, Cochrane Library and Web of Science, in order to compare active robotic-assisted TKA with the conventional technique. Data extraction and quality assessment were conducted for each study. Statistical analysis was performed using Revman V. 5.3.Results: Seven studies with a total of 517 knees undergoing TKA were included. Compared with conventional surgery, active robotic TKA showed better outcomes in precise mechanical alignment (mean difference, MD: - 0.82, 95% CI: -1.15 to - 0.49, p < 0.05) and implant position, with lower outliers (p < 0.05), better functional score (Western Ontario and McMaster University, Knee Society Score functional score) and less drainage (MD: - 293.28, 95% CI: - 417.77 to - 168.79, p < 0.05). No significant differences were observed when comparing the operation time, range of motion and complication rates.Conclusion: The current research demonstrates that active robotic-assisted TKA surgeries are more capable of improving mechanical alignment and prosthesis implantation when compared with conventional surgery. Further studies are required to investigate the potential benefits and long-term clinical outcomes of active robotic-assisted TKA. [ABSTRACT FROM AUTHOR]- Published
- 2019
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15. Tai Chi for Stroke Rehabilitation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
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Lyu, Diyang, Lyu, Xuanxin, Zhang, Yong, Ren, Yi, Yang, Fan, Zhou, Li, Zou, Yihuai, and Li, Zongheng
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STROKE ,TAI chi ,EXERCISE ,RANDOMIZED controlled trials ,META-analysis - Abstract
Background: Stroke is a major cause of poor health and has numerous complications. Tai Chi (TC) may have positive effects on the rehabilitation of stroke survivors, but recent clinical findings have not been included in previously published reviews. Objectives: We conducted this systematic review and meta-analysis to determine the effectiveness of all types of TC vs. conventional rehabilitation therapy for all aspects of stroke survivors' rehabilitation that have been studied. Method: We searched seven electronic literature databases (three in English, four in Chinese) and one clinical registry platform using established strategies to identify randomized controlled trials performed up to October 2017. Screening, quality assessment, and data collection were performed by two researchers separately, using the same standard. The results were analyzed using RevMan 5.3.0. The quality of evidence was evaluated with GRADEpro. Results: A total of 21 studies with 1,293 stroke survivors met inclusion criteria; 14 were included in the quantitative synthesis to evaluate four aspects and five outcomes. Nine studies indicated that TC was able to improve independent activities of daily living (ADL), especially TC vs. conventional rehabilitation therapy [mean difference (MD) [95% confidence interval (CI)] = 9.92 [6.82, 13.02], P < 0.00001]. Five studies reported significant effects of TC plus conventional rehabilitation therapy in increasing scores on the Fugl–Meyer Assessment for the upper limb [MD (95%CI) = 8.27 [4.69, 11.84], P < 0.0001], lower limb [MD (95%CI) = 2.75 [0.95, 4.56], P = 0.003], and overall [MD (95%CI) = 4.49 [1.92, 7.06], P = 0.0006]. The Berg Balance Scale revealed significant improvements according to pooled estimates for TC vs. conventional rehabilitation therapy [MD (95%CI) = 5.23 [3.42, 7.05], P < 0.00001]. TC plus conventional rehabilitation therapy also improved walking ability as measured by the Holden scale [MD (95%CI) = 0.61 [0.38, 0.85], P < 0.00001] and up-and-go time [MD (95%CI) = 2.59 [1.76, 3.43], P < 0.00001]. Conclusion: TC has an overall beneficial effect on ADL, balance, limb motor function, and walking ability among stroke survivors, based on very low-quality evidence, and may also improve sleep quality, mood, mental health, and other motor function. Well-designed, higher-quality trials with longer-term follow-up periods are needed to develop better-quality evidence. [ABSTRACT FROM AUTHOR]
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- 2018
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16. Open versus endoscopic in situ decompression in cubital tunnel syndrome: A systematic review and meta-analysis.
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Ren, Yi-Ming, Zhou, Xian-Hu, Qiao, Hu-Yun, Wei, Zhi-Jian, Fan, Bao-You, Lin, Wei, and Feng, Shi-Qing
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ENDOSCOPY ,META-analysis ,SYSTEMATIC reviews ,SURGICAL decompression ,CUBITAL tunnel syndrome - Abstract
Objective: We conducted this systematic review and meta-analysis to compare the clinical efficacy and safety between open and endoscopic in situ decompression surgery methods for cubital tunnel syndrome (CuTS).Methods: PubMed, Medline, Embase, Cochrane Library and CNKI were searched for eligible studies. The data were extracted by two of the coauthors (WL, BYF) independently and were analyzed using RevMan statistical software, version 5.1. Relative risks (RRs) and 95% confidence intervals (CIs) were calculated. Cochrane Collaboration's Risk of Bias Tool and the Newcastle-Ottawa Scale were used to assess the risk of bias.Results: Seven studies were included for systematic review, and six studies were included for meta-analysis. The CuTS patients received open in situ decompression (OISD) or endoscopic in situ decompression (EISD). A pooled analysis of postoperative Bishop score showed that the difference was not statistically significant between the EISD group and the OISD group (RR = 0.99, 95% CI = 0.88-1.12, P = 0.88). The overall estimate of postoperative satisfaction between the EISD group and the OISD group was not found to be significant (RR = 0.98, 95% CI = 0.89-1.08, P = 0.70). The overall estimate of complications (RR = 0.88, 95% CI = 0.24-3.29, P = 0.85) suggested that the difference was not statistically significant.Conclusions: EISD and OISD for treating CuTS have equivalent efficacy for postoperative clinical improvement, whereas the incidences of complications of endoscopic surgical procedure were also same as those with the open surgical procedure. In situ decompression (especially EISD, with minor intraoperative trauma) could be treated as a valuable alternative to treat CuTS. [ABSTRACT FROM AUTHOR]- Published
- 2016
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17. Recombinant Tissue Plasminogen Activator Induces Neurological Side Effects Independent on Thrombolysis in Mechanical Animal Models of Focal Cerebral Infarction: A Systematic Review and Meta-Analysis.
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Dong, Mei-Xue, Hu, Qing-Chuan, Shen, Peng, Pan, Jun-Xi, Wei, You-Dong, Liu, Yi-Yun, Ren, Yi-Fei, Liang, Zi-Hong, Wang, Hai-Yang, Zhao, Li-Bo, and Xie, Peng
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RECOMBINASES ,PLASMINOGEN ,THROMBOLYTIC therapy ,CEREBRAL infarction ,META-analysis - Abstract
Background and Purpose: Recombinant tissue plasminogen activator (rtPA) is the only effective drug approved by US FDA to treat ischemic stroke, and it contains pleiotropic effects besides thrombolysis. We performed a meta-analysis to clarify effect of tissue plasminogen activator (tPA) on cerebral infarction besides its thrombolysis property in mechanical animal stroke. Methods: Relevant studies were identified by two reviewers after searching online databases, including Pubmed, Embase, and ScienceDirect, from 1979 to 2016. We identified 6, 65, 17, 12, 16, 12 and 13 comparisons reporting effect of endogenous tPA on infarction volume and effects of rtPA on infarction volume, blood-brain barrier, brain edema, intracerebral hemorrhage, neurological function and mortality rate in all 47 included studies. Standardized mean differences for continuous measures and risk ratio for dichotomous measures were calculated to assess the effects of endogenous tPA and rtPA on cerebral infarction in animals. The quality of included studies was assessed using the Stroke Therapy Academic Industry Roundtable score. Subgroup analysis, meta-regression and sensitivity analysis were performed to explore sources of heterogeneity. Funnel plot, Trim and Fill method and Egger’s test were obtained to detect publication bias. Results: We found that both endogenous tPA and rtPA had not enlarged infarction volume, or deteriorated neurological function. However, rtPA would disrupt blood-brain barrier, aggravate brain edema, induce intracerebral hemorrhage and increase mortality rate. Conclusions: This meta-analysis reveals rtPA can lead to neurological side effects besides thrombolysis in mechanical animal stroke, which may account for clinical exacerbation for stroke patients that do not achieve vascular recanalization with rtPA. [ABSTRACT FROM AUTHOR]
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- 2016
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18. Association between serotonin transporter (SERT) gene polymorphism and idiopathic pulmonary arterial hypertension: a meta-analysis and review of the literature.
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Zhang, Hang, Xu, Meng, Xia, Jia, and Qin, Ren-Yi
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SEROTONIN transporters ,GENETIC polymorphisms ,PULMONARY artery diseases ,HYPERTENSION ,META-analysis ,MEDICAL literature reviews ,ETIOLOGY of diseases ,ALLELES - Abstract
Abstract: Objective: Idiopathic pulmonary arterial hypertension (IPAH) is a rare and often fatal disease of unknown etiology. Serotonin transporter (SERT) protein, whose genes can have two allelic forms, namely long (L) and short (S), is suspected to be related to IPAH risk. Several studies have investigated the association between SERT's different allelic forms and IPAH but showed conflicting results. A meta-analysis of published studies was performed to allow a more reliable estimate of this association. Methods: Relevant databases were searched to identify eligible studies published from 2000 to 2013. Odds ratios (OR) and 95% confidence intervals (CI) were determined for the gene–disease association using fixed or random effects models. Results: A total of 6 studies with 451 IPAH subjects and 664 controls were included in this meta-analysis. A significant difference was found in the comparison between IPAH subjects and controls with LL vs. SS genotypes, and the pooled odds ratio (OR) with the fixed effects model was 1.446 (95% CI=1.036–2.018, p=0.030, I
2 =38.8%). However, no statistically significant differences were observed for LL vs. LS or LL vs. LS + SS. The pooled OR indicated no significant differences in IPAH risk between carriers of SERT L and S alleles (ORL VS. S =1.327, 95% CI=0.933–1.886, p=0.115). Conclusion: This meta-analysis provides evidence suggesting an association between the SERT L/S polymorphism and IPAH. Individuals with the LL genotype have an obviously higher risk of developing IPAH than those with the SS genotype. [Copyright &y& Elsevier]- Published
- 2013
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19. Advances in Liquid Metal-Enabled Flexible and Wearable Sensors.
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Ren, Yi, Sun, Xuyang, and Liu, Jing
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ELECTRONIC paper ,LIQUID metals ,DETECTORS ,META-analysis - Abstract
Sensors are core elements to directly obtain information from surrounding objects for further detecting, judging and controlling purposes. With the rapid development of soft electronics, flexible sensors have made considerable progress, and can better fit the objects to detect and, thus respond to changes more sensitively. Recently, as a newly emerging electronic ink, liquid metal is being increasingly investigated to realize various electronic elements, especially soft ones. Compared to conventional soft sensors, the introduction of liquid metal shows rather unique advantages. Due to excellent flexibility and conductivity, liquid-metal soft sensors present high enhancement in sensitivity and precision, thus producing many profound applications. So far, a series of flexible and wearable sensors based on liquid metal have been designed and tested. Their applications have also witnessed a growing exploration in biomedical areas, including health-monitoring, electronic skin, wearable devices and intelligent robots etc. This article presents a systematic review of the typical progress of liquid metal-enabled soft sensors, including material innovations, fabrication strategies, fundamental principles, representative application examples, and so on. The perspectives of liquid-metal soft sensors is finally interpreted to conclude the future challenges and opportunities. [ABSTRACT FROM AUTHOR]
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- 2020
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20. Is arthroscopic repair superior to biceps tenotomy and tenodesis for type II SLAP lesions? A meta-analysis of RCTs and observational studies.
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Ren, Yi-Ming, Duan, Yuan-Hui, Sun, Yun-Bo, Yang, Tao, Hou, Wei-Yu, and Tian, Meng-Qiang
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ARTHROSCOPY , *CONFIDENCE intervals , *INFORMATION storage & retrieval systems , *MEDICAL databases , *MEDICAL information storage & retrieval systems , *MEDLINE , *META-analysis , *SCIENTIFIC observation , *ONLINE information services , *PATIENT satisfaction , *RISK assessment , *SHOULDER injuries , *SURGICAL complications , *TENOTOMY , *SYSTEMATIC reviews , *RANDOMIZED controlled trials , *TREATMENT effectiveness , *RESEARCH bias , *TENODESIS , *ODDS ratio - Abstract
Objective: Labral repair and biceps tenotomy and tenodesis are routine operations for type II superior labrum anterior posterior (SLAP) lesion of the shoulder, but evidence of their superiority is lacking. We conducted this systematic review and meta-analysis to compare the clinical outcomes of arthroscopic repair versus biceps tenotomy and tenodesis intervention. Methods: The eight studies were acquired from PubMed, Medline, Embase, CNKI, and Cochrane Library. The data were extracted by two of the coauthors independently and were analyzed by RevMan 5.3. Mean differences (MDs), odds ratios (ORs), and 95% confidence intervals (CIs) were calculated. Cochrane Collaboration's Risk of Bias Tool and Newcastle–Ottawa Scale were used to assess risk of bias. Results: Eight studies including two randomized controlled trials (RCTs) and six observational studies were assessed. The methodological quality of the trials ranged from low to moderate. The pooled results of UCLA score, SST score, and complications showed that the differences were not statistically significant between the two interventions. The difference of ASES score and satisfaction rate was statistically significant between arthroscopic repair and biceps tenotomy and tenodesis intervention, and arthroscopic biceps tenotomy and tenodesis treatment was more effective. Sensitivity analysis proved the stability of the pooled results, and there were too less included articles to verify the publication bias. Conclusions: Both arthroscopic repair and biceps tenotomy and tenodesis interventions had benefits in type II SLAP lesions. Arthroscopic biceps tenotomy and tenodesis treatment provides better clinical outcome in ASES score and satisfaction rate and comparable complications compared with arthroscopic repair treatment. In view of the heterogeneity and confounding factors, whether these conclusions are applicable should be further determined in future studies. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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