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The article discusses the first Early Researchers' Seminar for Science and Speculative Fiction, which took place at the University of Salamanca in Spain. The seminar featured a series of panels and discussions on various topics related to speculative fiction, including gendered geographies, posthumanism, and contemporary speculative literature. The speakers aimed to deliver accessible talks that catered to a diverse audience, from established researchers to undergraduate students. The seminar provided a welcoming and non-commodified space for the exchange of ideas and fostered discussions on topics such as feminist speculation, posthuman bodies, and the critical potentials of speculative fiction. [Extracted from the article]

Nitrate pollution in aquifers is a global concern. Spain has developed a national strategy to recover nitrate polluted aquifers aligned with the European Union (EU) policies, specifically through the water planning under the EU Water Framework Directive. River basin management plans use PATRICAL model results to define the maximum nitrogen surplus in each polluted aquifer for the first time. The maximum nitrogen surplus allows to reach the good status in each aquifer and the model provides the number of years required. Around 30% of the aquifers in Spain is currently heavily polluted by nitrates. Model results show that 90% of these aquifers can be recovered in next 6–12 years by increasing nitrogen use efficiency and reducing nitrogen losses around 50%, which is in line with the EU Farm to Fork Strategy. The remaining aquifers require additional reductions to achieve the good status. In Spain this increase in nitrogen efficiency can be obtained with different measures including 30% reduction of current fertilization. [Display omitted] • Spanish strategy to recover nitrate polluted aquifers is perfectly aligned with the European Farm to Fork Strategy. • In Spain 30% of aquifers have high nitrate levels. • PATRICAL model results define maximum nitrogen surplus in each aquifer. • 90 % of groundwater can be recovered reducing nitrogen losses by 50%. • Recovery time required is between 6 and 12 years for most aquifers. [ABSTRACT FROM AUTHOR]

Summary This study aims to give voice to parents and gather their views about contact visits in foster care. Participants were 23 birth families who had contact visits with 35 children in non-kinship foster care. Semistructured individual interviews were conducted in order to explore two key aspects: the parents' opinions regarding the contact visits and the main areas they felt needed improving. The interviews were transcribed and the transcripts were examined using an inductive method by Atlas.ti. Findings The main themes to emerge concerned their general view of contact visits, the input and support from social workers, the contribution of foster families, the contact venue, and the organization of visits. In general, the birth families' comments were positive about the support and treatment received from social workers. However, they also mentioned certain aspects should be improved, such as supervision during visits. Applications The results suggest several ways to improve social work practice. Social workers should aim to involve birth families more in the process of drawing up contact arrangements and offering birth families adequate preparation prior to visits. Child protection agencies also have a role to play in relation to improving the facilities in which visits are held, as well as their overall organization, such as, the venue should provide a space that enables everyday family relationships to take place, and in the absence of this, attempts should be made to organize visits outside the official meeting place. [ABSTRACT FROM AUTHOR]

Graphical abstract Highlights • Solar PV and self-consumption have been halted in Spain due to several barriers. • Un unstable regulatory framework for self-consumption influences its deployment. • Strategies to accelerate high solar photovoltaic growth rates in Spain are proposed. • Measures to promote PV integration in distribution may have a positive impact. Abstract Despite the Spanish privileged geographical location and business leadership in the renewable energy field, currently is can be observed that the solar photovoltaic generation, electric self-consumption systems and net-metering policies deployment is much lower than it can be observed in other countries, even with lower energy sources for self-consumption. Energy policy experts assess as main reason the absence of a stable regulatory framework and the existence of clear disincentives. These disincentives are based on several economic non-market failures and institutional barriers. One key factor has proven to be the regulatory uncertainty created mainly by the recent national most relevant ministerial orders regarding energy generation and consumption, which suggests that, de facto , the regulatory framework is currently still under development. This paper includes first a brief but deep description of the prosumers penetration existing scenario in Spain, and then it focuses on feasible strategies to accelerate higher solar photovoltaic and self-consumption growth rates in Spain. Then, new policy measures to eliminate, or at least, mitigate, current barriers to their deployment are proposed and discussed. It is concluded that it results mandatory the urgent modernization of the energy regulatory framework promoting an active role for distributed PV generation which could have a significant positive impact in the voltage control and frequency regulation in distribution networks, among other advantages. [ABSTRACT FROM AUTHOR]

Droughts are one of the gravest natural threats currently existing in the world and their occurrence and intensity might be exacerbated in the coming years due to climate change. The severe impacts that droughts cause to inland water resources and to the associated socio-economic activities justify the continuous monitoring of the drought. The case study presented shows a practical application of a distributed drought monitoring system implemented in a real river basin district, the Júcar River Basin District (43,000 km 2 ), where drought periods of marked intensity have occurred historically and the climate ranges from humid in the north to semiarid in the south. Five drought indices have been applied: Standardised Precipitation Index (SPI) for meteorological drought; Palmer Drought Severity Index (PDSI) and a new soil moisture index (HI), for edaphic drought; Normalised Difference Vegetation Index (NDVI) for the vegetation activity; and Spanish Status Index (SI), for the operational drought. All indices are standardised to compare them. The relationship between the standardised operational drought index SI and the long-term meteorological indices, SPI-12 or SPI-24, show that in a medium size basin the concept of “prolonged drought” required by the European Commission under the Water Framework Directive could be defined by the use of accumulated precipitation indices. The number of months to be accumulated depends on the size of the basin and the water management system properties. In large basins, such as the Júcar river basin (22,000 km 2 ), there are significant deviations due to the spatial distribution of the drought. The use of a unique aggregated indicator could hide a significant drought in a specific area, or on the other hand show a non-real drought. Evolution of drought indices for each water management system must be accompanied by spatially distributed drought maps to better understand the drought status and its evolution. [ABSTRACT FROM AUTHOR]

The Questionnaire on the Frequency of and Satisfaction with Social Support (QFSSS) was designed to assess the frequency of and the degree of satisfaction with perceived social support received from different sources in relation to three types of support: emotional, informational and instrumental. This study tested the reliability of the questionnaire and its criterion and structural validity. The data were drawn from survey interviews of 2042 Spanish people. The results show high internal consistency (values of Cronbach's alpha range from .763 to .952). The correlational analysis showed significant positive associations between QFSSS scores and measures of subjective well-being and perceived social support, as well as significant negative associations with measures of loneliness (Pearson's r correlation range from .11 to .97). Confirmatory factor analysis by Structural Equation Modeling suggested an internal 4-factor structure that corresponds to the sources of support analyzed: partner, family, friends and community (values for the Goodness of Fit Index (GFI) range from .93 to .95; for the Comparative Fit Index (CFI) range from .95 to .98; for Root Mean Square Error of Approximation (RMSEA) range from .10 to .07). These results confirm the QFSSS validity as a versatile tool, suitable for the detailed assessment of social support. [ABSTRACT FROM AUTHOR]

Various studies have analyzed the variables that influence the outcome of family foster care. The research aimed to determine whether distinct profiles of foster placements can be identified on the basis of key variables, seeking at the same time to define a predictive function for the success or failure of foster care. Participants were the foster families of 104 non-relative foster children. A k-means cluster analysis identified three clusters, corresponding to high-, moderate-, and low-risk placements. The variables that formed part of these clusters were behavior problems and impulsivity/inattention in foster children, level of burden in the foster parents, an authoritarian parenting style, and criticism/rejection by the foster parents. A discriminant analysis confirmed the differences between the three clusters and enabled the researchers to create a function for classifying cases in each group. These results can be used to identify at-risk placements and may help to avoid situations that could undermine the foster child's development. The findings could also be useful in terms of assessing the suitability of foster families, as well for identifying their training needs. [ABSTRACT FROM AUTHOR]

Spain was one of the pioneers in the deployment of wind energy systems worldwide and thus since 2014 has a potential for repowering that reaches between 3.3 and 8.7 GW in 2021 (12%–32% of its current installed wind capacity). However, despite the technical and economic advantages, we have observed little interest from promoters in the repowering of already amortized wind farms. The aim of the proposed study is to depict the background framework of barriers for repowering wind farms, which is specially affecting to Spain, but that can also extend to other EU countries. Therefore, we conducted a systematic survey study with academics, promoters, financial experts, manufacturers, operators, maintainers and policymakers to identify and understand the existing real and practical barriers. As a result, we have identified 34 major barriers covering five categories: technical issues, economics, environmental considerations, social concerns, and regulatory and administrative hurdles. We then asked the experts to rate these barriers based on their impact or relevance. We found that the experts agree that regulatory and administrative barriers have the maximum impact, while economic, environmental and technical barriers have only a mid-high impact. Therefore, we can conclude that, in general, the Administration must develop a concise and stable regulatory framework for all RES, especially for repowering projects, and carry out a review of both the technical requirements and the incentives schemes, with a focus on energy efficiency. • We identify and score technical, economic, regulatory, environmental and social barriers for wind repowering. • Our analysis is supported by a panel of experts with different roles in the wind energy industry. • We have scored existing barriers according to their potential impact on the repowering decision. • iWe propose a feasible framework of general measures to overcome the identified barriers and promote wind repowering. • We conclude that it must be developed a stable regulatory framework for repowering with a focus on the energy efficiency. [ABSTRACT FROM AUTHOR]

The main aim of this study was to identify the factors which are related to the greatest emotional and behavioral problems among children in the context of a foster family. Participants were 104 non-relative foster children and their respective foster families. A structural equation model was designed and tested in order to identify an explanatory model among the most relevant of the studied variables. The results showed that the model obtained offers a satisfactory structural fit and provides good explanatory power for children's problems. More specifically, the data reveal the important role played by affective relationships and parental discipline style in relation to children's problems within the foster family. Other factors involved were also analyzed. These results indicate that both parenting style and the kind of affect shown by foster parents towards the child are important predictors of the latter's problems. Criticism/rejection on the part of foster parents increases problems through its influence on both the foster carer's burden and the child's self-esteem. These results are useful in order to prepare and support foster carers. [ABSTRACT FROM AUTHOR]

Background: In patients treated with oral anticoagulants, subcutaneous injections of anti-tetanus vaccine are usually recommended to reduce the risk of bleeding, although the effectiveness of the vaccine has only been proven for intramuscular injection. The objective of this study was to compare the safety and efficacy of intramuscular and subcutaneous injections of tetanus-diphtheria vaccine in patients treated with oral anticoagulants. Methods/design: We present a prospective, double blinded, clinical trial comparing two groups of patients with oral anticoagulants: one group was administered tetanus-diphtheria vaccine by intramuscular injection, while the other was administered the same vaccine by subcutaneous injection. Allocation to each group was randomized and the duration of the study was six years. Study population: all patients treated with oral anticoagulants, who had been administered with at least one dose of vaccine, at 15 Health Centres in Vigo (Spain), and who agreed to participate in the study. The sample size was 115 patients in each group. The main variables for the safety analysis were the measurement of the brachial diameter, the appearance of basic injuries at the vaccine administration site, the appearance of pain and systemic reactions. The variable used for the efficacy analysis was a significant increase in the titres of anti-tetanus toxoid antibodies. An Intention-to-treat analysis will be performed. Details will be classified according to the administration route, while within each group a 3-tiered stratification will be defined by the administered number of doses. As a measure of association, relative risk will be estimated; the reduction of relative risk will also measured. For safety and to control the confounder effect, a logistic regression analysis will be carried out. As a measure of impact the reduction of absolute risk in relation to the total number of patients to be treated and the Number Needed to Treat will be estimated. CONSORT 2010 guidelines were applied for reporting parallel group randomised trials. Discussion: The most significant difficulties on the project are related to the large number of participating centres, required to obtain a viable study population sample size, and the coordination given the scattering of the centres and researchers. Trial registration: ISRCTN69942081. [ABSTRACT FROM AUTHOR]

Abstract: This paper describes two different GIS models – one stationary (GeoImpress) and the other non-stationary (Patrical) – that assess water quantity and quality in the Júcar River Basin District, a large river basin district (43,000km2) located in Spain. It aims to analyze the status of surface water (SW) and groundwater (GW) bodies in relation to the European Water Framework Directive (WFD) and to support measures to achieve the WFD objectives. The non-stationary model is used for quantitative analysis of water resources, including long-term water resource assessment; estimation of available GW resources; and evaluation of climate change impact on water resources. The main results obtained are the following: recent water resources have been reduced by approximately 18% compared to the reference period 1961–1990; the GW environmental volume required to accomplish the WFD objectives is approximately 30% of the GW annual resources; and the climate change impact on water resources for the short-term (2010–2040), based on a dynamic downscaling A1B scenario, implies a reduction in water resources by approximately 19% compared to 1990–2000 and a reduction of approximately 40–50% for the long-term (2070–2100), based on dynamic downscaling A2 and B2 scenarios. The model also assesses the impact of various fertilizer application scenarios on the status of future GW quality (nitrate) and if these future statuses will meet the WFD requirements. The stationary model generates data on the actual and future chemical status of SW bodies in the river basin according to the modeled scenarios and reflects the implementation of different types of measures to accomplish the Urban Waste Water Treatment Directive and the WFD. Finally, the selection and prioritization of additional measures to accomplish the WFD are based on cost-effectiveness analysis. [Copyright &y& Elsevier]

Lake Albufera (Valencia, Spain) is part of a legally protected wetland of international importance. However, it has deteriorated as a result of urban, industrial, and farming pollution. It is highly eutrophic, and its sediment contains persistent pollutants, such as heavy metals. In anoxic sediments, sulphides represent an important binding phase for heavy metals. In this study, acid volatile sulphide (AVS) and simultaneously extracted metals (SEM) were analyzed in surface sediment extracted from Lake Albufera; organic matter and total metals were also analyzed. Twelve sites were sampled in each of three sampling campaigns conducted in March and September 2007 and September 2008. The results revealed elevated organic matter contents varying between 6.9 and 16.7%. The concentrations of AVS in the lake were high, ranging from 8.5 to 48.5 μmol/g; the lowest concentrations were found in the central sites. The AVS results displayed significant differences between the samples from the winter and summer of 2007 (p < 0.05) but not between the two summer samples. The results obtained for SEM varied from 1.4 to 4.8 μmol/g. The difference SEM-AVS was less than zero for all sampling locations and campaigns, indicating the existence of a sulphide pool able to bind metals. [ABSTRACT FROM PUBLISHER]

Introduction: Teledermatology is the practice of dermatology through communication technologies. The aim of this study is to analyze its implementation in a Spanish health area during its first two years. Methods: Cross-sectional descriptive study. It included interconsultations between dermatologists and family physicians in the Salamanca Health Area (Spain) after the implementation of the non-face-to-face modality over a period of two consecutive years. A total of 25,424 consultations were performed (20,912 face-to-face and 4,512 non-face-to-face); 1000 were selected by random sampling, half of each modality. Main measures: referral rate, response time and resolution time, type of pathology, diagnostic concordance, and quality of consultation. Results: The annual referral rate was 42.9/1000 inhabitants (35.3 face-to-face and 7.6 non-face- to-face). The rate of face-to-face referrals was higher in urban areas (37.1) and the rate of non- face-to-face referrals in rural areas (10.4). The response time for non-face-to-face consultations was 2.4 ± 12.7 days and 56 ± 34.8 days for face-to-face consultations (p < 0.001). The resolution rate for non-face-to-face consultations was 44%. Diagnostic concordance, assessed by the kappa index, was 0.527 for face-to-face consultations and 0.564 for non-face-to-face consultations. Greater compliance with the quality criteria in the non-attendance consultations. Conclusions: Teledermatology appears to be an efficient tool in the resolution of dermatological problems, with a rapid, effective, and higher quality response for attention to skin pathologies. Registry: ClinicalTrials.gov Identifier: NCT05625295. Registered on 21 November 2022 (https://clinicaltrials.gov/ct2/show/ NCT05625295). [ABSTRACT FROM AUTHOR]

The social practice of games of chance and gambling can be read in an interesting variety of ways in the area of the Social Sciences. One is the geographical perspective, which highlights the spatial repercussions of this form of recreation. However, in Spain, very little scientific literature exists on the topic, which justifies the appropriateness of this contribution to promote the necessary debate on the matter. A variety of statistical and legal sources are treated to reach the following results: Spain is in a leading position in the gambling industry at the international level, which can be attributed to its land-based gambling infrastructure and, specifically, the popularity of Electronic Machines and their proliferation in both catering establishments and specific venues. An analysis of gambling distribution in Spain shows a relatively homogeneous interregional situation in this regard, as no clear spatial patterns have been found apart from the demographic weight of the different regions. Thus, it is relevant to raise the question whether the legal differences between the regions have been a factor in gambling's spatial distribution. To conclude, we detail some of the most demanding problem areas that require follow-up geographical research on the Spanish gambling landscape, although it would be desirable for the quality, variety and accessibility of data to be improved. [ABSTRACT FROM AUTHOR]

Simple Summary: Penile cancer is a rare malignant tumor mainly affecting adult/older men. Given the rarity of this disease, affecting 1/100,000 men every year, risk factors and diagnostic procedures are often inadequately described. This is the first multicenter study to describe the approach to this disease in Spain. The results highlight the need for the institution of referral centers and standardized diagnostic pathways for the optimal management of this disease. Introduction: Penile cancer (PC) is a rare malignancy with an overall incidence in Europe of 1/100,000 males/year. In Europe, few studies report the epidemiology, risk factors, clinical presentation, and treatment of PC. The aim of this study is to present an updated outlook on the aforementioned factors of PC in Spain. Materials and Methods: A multicentric, retrospective, observational epidemiological study was designed, and patients with a new diagnosis of PC in 2015 were included. Patients were anonymously identified from the Register of Specialized Care Activity of the Ministry of Health of Spain. All Spanish hospitals recruiting patients in 2015 were invited to participate in the present study. We have followed a descriptive narration of the observed data. Continuous and categorical data were reported by median (p25th–p75th range) and absolute and relative frequencies, respectively. The incidence map shows differences between Spanish regions. Results: The incidence of PC in Spain in 2015 was 2.55/100,000 males per year. A total of 586 patients were identified, and 228 patients from 61 hospitals were included in the analysis. A total of 54/61 (88.5%) centers reported ≤ 5 new cases. The patients accessed the urologist for visually-assessed penile lesions (60.5%), mainly localized in the glans (63.6%). Local hygiene, smoking habits, sexual habits, HPV exposure, and history of penile lesions were reported in 48.2%, 59.6%, 25%, 13.2%, and 69.7%. HPV-positive lesions were 18.1% (28.6% HPV-16). The majority of PC was squamous carcinoma (95.2%). PC was ≥cT2 in 45.2% (103/228) cases. At final pathology, PC was ≥pT2 in 51% of patients and ≥pN1 in 17% of cases. The most common local treatment was partial penectomy (46.9% cases). A total of 47/55 (85.5%) inguinal lymphadenectomies were open. Patients with ≥pN1 disease were treated with chemotherapy in 12/39 (40.8%) of cases. Conclusions: PC incidence is relatively high in Spain compared to other European countries. The risk factors for PC are usually misreported. The diagnosis and management of PC are suboptimal, encouraging the identification of referral centers for PC management. [ABSTRACT FROM AUTHOR]

Background: The wide use of the Internet in the workplace, academic or social field, can have an impact on daily life. One of the most used questionnaires worldwide to analyse these problems is the Internet Addiction Test (IAT). Our aim was to validate a Spanish version of the IAT and analyse its psychometric properties.Methods: Population of study were college students participating in the uniHcos project (Universities of Granada, Huelva, Jaén, León, Salamanca, and Vigo). The questionnaire was translated and back-translated by two native English speakers. Reliability of scores was analysed using Pearson's correlation coefficient and agreement was analysed using the Bland-Altman and Kappa techniques. Test dimensions were analysed by exploratory and confirmatory factor analysis.Results: The reliability of scores was good (r = 0.899, Kappa = 0.650 and mean difference using Bland-Altman = -3.5). The psychometric assessment identified two factors (Emotional Investment; Performance and Time Management) which explained 55 % of the variance (total internal consistency of 0.91) and only 19 items. The confirmatory analysis showed an acceptable goodness of fit, especially when items 6 and 8 were related (RMSEA = 0.07 90%IC = 0.06 - 0.08; WRMR = 1.01, CFI = 0.96; TLI = 0.95). The two dimensions were negatively correlated with age and positively correlated with time spent online, especially for the purposes of leisure and entertainment.Discussion: The results show good reliability and psychometric properties of the Spanish version of IAT with a two-dimensional solution. This result is partially in concordance with previous validations of the IAT in other languages that have found uni- and multi-dimensional solutions using different methodologies. Moreover, we want to highlight the possibility that some item of this questionnaire is outdated due to the technological and lifestyles changes and should be not taken into account.Conclusion: The reliability and psychometric properties obtained in this study support the conclusion that this Spanish short version of the IAT represents a useful tool for the analysis of problems arising from misuse of the Internet. [ABSTRACT FROM AUTHOR]

Background: Mitochondrial diseases are difficult to diagnose and treat. Recent advances in genetic diagnostics and more effective treatment options can improve patient diagnosis and prognosis, but patients with mitochondrial disease typically experience delays in diagnosis and treatment. Here, we describe a unique collaborative practice model among physicians and scientists in Spain focused on identifying TK2 deficiency (TK2d), an ultra-rare mitochondrial DNA depletion and deletions syndrome.Main Body: This collaboration spans research and clinical care, including laboratory scientists, adult and pediatric neuromuscular clinicians, geneticists, and pathologists, and has resulted in diagnosis and consolidation of care for patients with TK2d. The incidence of TK2d is not known; however, the first clinical cases of TK2d were reported in 2001, and only ~ 107 unique cases had been reported as of 2018. This unique collaboration in Spain has led to the diagnosis of more than 30 patients with genetically confirmed TK2d across different regions of the country. Research affiliate centers have led investigative treatment with nucleosides based on understanding of TK2d clinical manifestations and disease mechanisms, which resulted in successful treatment of a TK2d mouse model with nucleotide therapy in 2010. Only 1 year later, this collaboration enabled rapid adoption of treatment with pyrimidine nucleotides (and later, nucleosides) under compassionate use. Success in TK2d diagnosis and treatment in Spain is attributable to two important factors: Spain's fully public national healthcare system, and the designation in 2015 of major National Reference Centers for Neuromuscular Disorders (CSURs). CSUR networking and dissemination facilitated development of a collaborative care network for TK2d disease, wherein participants share information and protocols to request approval from the Ministry of Health to initiate nucleoside therapy. Data have recently been collected in a retrospective study conducted under a Good Clinical Practice-compliant protocol to support development of a new therapeutic approach for TK2d, a progressive disease with no approved therapies.Conclusions: The Spanish experience in diagnosis and treatment of TK2d is a model for the diagnosis and development of new treatments for very rare diseases within an existing healthcare system. [ABSTRACT FROM AUTHOR]

Background: To identify and quantify associations between baseline characteristics on hospital admission and mortality in patients with COVID-19 at a tertiary hospital in Spain. Methods and findings: This retrospective case series included 238 patients hospitalized for COVID-19 at Hospital Universitario Clínico San Cecilio (Granada, Spain) who were discharged or who died. Electronic medical records were reviewed to obtain information on sex, age, personal antecedents, clinical features, findings on physical examination, and laboratory results for each patient. Associations between mortality and baseline characteristics were estimated as hazard ratios (HR) calculated with Cox regression models. Series mortality was 25.6%. Among patients with dependence for basic activities of daily living, 78.7% died, and among patients residing in retirement homes, 80.8% died. The variables most clearly associated with a greater hazard of death were age (3% HR increase per 1-year increase in age; 95%CI 1–6), diabetes mellitus (HR 2.42, 95%CI 1.43–4.09), SatO2/FiO2 ratio (43% HR reduction per 1-point increase; 95%CI 23–57), SOFA score (19% HR increase per 1-point increase, 95%CI 5–34) and CURB-65 score (76% HR increase per 1-point increase, 95%CI 23–143). Conclusions: The patients residing in retirement homes showed great vulnerability. The main baseline factors that were independently associated with mortality in patients hospitalized for COVID-19 were older age, diabetes mellitus, low SatO2/FiO2 ratio, and high SOFA and CURB-65 scores. [ABSTRACT FROM AUTHOR]

This study analyzes the opinions of foster families and social workers regarding the benefits and problems associated with contact visits. Data were gathered through two focus groups, comprising social workers and foster carers, respectively. Both groups agreed that visits were useful for maintaining foster children's attachment to their birth family, for enhancing their psychological wellbeing and for helping them to understand the real situation of their birth family. Regarding difficulties, the two groups highlighted problems of coordination between social workers and foster families, as well as a lack of support and preparation for foster carers, children, and birth families. [ABSTRACT FROM AUTHOR]

Migration is an example of adaptation with enduring effects over time and in different cultures. Few studies have analyzed the effect of the sense of community (SOC) on satisfaction with life (SWL) over time while taking into account the moderating effects of sociodemographic characteristics. We propose a model that explains the influence of time of residence on the SOC and SWL. It was hypothesized that the SOC has a positive influence on SWL and that SWL is moderated by sociodemographic characteristics and cultural differences. Participants were 2,211 immigrants residing in Malaga (Spain). Results show a positive association between years of residence and the SOC and the SWL. A positive association was found between the SOC and SWL. This study shows the relevance of analyzing the moderating effects of sociodemographic characteristics in different immigrant groups rather than according to the migration process as a whole to develop specific intervention strategies. [ABSTRACT FROM AUTHOR]

Migration is an example of adaptation with enduring effects over time and in different cultures. Few studies have analyzed the effect of the sense of community (SOC) on satisfaction with life (SWL) over time while taking into account the moderating effects of sociodemographic characteristics. We propose a model that explains the influence of time of residence on the SOC and SWL. It was hypothesized that the SOC has a positive influence on SWL and that SWL is moderated by sociodemographic characteristics and cultural differences. Participants were 2,211 immigrants residing in Malaga (Spain). Results show a positive association between years of residence and the SOC and the SWL. A positive association was found between the SOC and SWL. This study shows the relevance of analyzing the moderating effects of sociodemographic characteristics in different immigrant groups rather than according to the migration process as a whole to develop specific intervention strategies. [ABSTRACT FROM AUTHOR]

Background: Fostering a culture of safety is an essential step in ensuring patient safety and quality in primary care. We aimed to evaluate the effectiveness of an educational intervention to improve the safety culture in the family and community medicine teaching units in an Atlantic European Region. Methods: Randomized study conducted in family and community medicine teaching units in Galicia (Spain). Participants were all fourth-year residents and their tutors (N = 138). Those who agreed to participate were randomized into one of two groups (27 tutors/26 residents in the intervention group, 23 tutors/ 23 residents in the control one).All were sent the Survey on Patient Safety Culture. After that, the intervention group received specific training in safety; they also recorded incidents over 15 days, documented them following a structured approach, and had feedback on their performance. The control group did not receive any action. All participants completed the same survey four months later. Outcome measures were the changes in safety culture as quantified by the results variables of the Survey: Patient Safety Grade and Number of events reported. We conducted bivariate and adjusted analyses for the outcome measures. To explore the influence of participants' demographic characteristics and their evaluation of the 12 dimensions of the safety culture, we fitted a multivariate model for each outcome. Results: Trial followed published protocol. There were 19 drop outs. The groups were comparable in outcome and independent variables at start. The experiment did not have any effect on Patient safety grade (− 0.040) in bivariate analysis. The odds of reporting one to two events increased by 1.14 (0.39–3.35), and by 13.75 (2.41–354.37) the odds of reporting 3 or more events. Different dimensions had significant independent effects on each outcome variable. Conclusion: A educational intervention in family and community medicine teaching units may improve the incidents reported. The associations observed among organizational dimensions and outcomes evidence the complexity of patient safety culture measurement and, also, show the paths for improvement. In the future, it would be worthwhile to replicate this study in teaching units from different settings and with different health professionals engaged. Trial registration: It was retrospectively registered with (ISRCTN41911128, 31/12/2010). [ABSTRACT FROM AUTHOR]

It has been argued that contact visits between foster children and birth parents can help maintain attachment bonds and support the child's development. However, some research suggests that such visits can be detrimental. This study analyses the characteristics of contact visits and examines children's perceptions of the emotional relationship they have with foster carers and their biological parents. Participants were 104 non‐kinship foster children and their respective foster carers and social workers. Fifty‐six of these foster children had contact visits with their birth parents. Foster children rated the quality of their relationship with foster carers and birth parents using the Affect Scale. Foster children, foster carers and social workers all completed the Evaluation of Contact Visits Questionnaire. Results showed that (i) a high proportion of children had no contact visits; (ii) the contact agreement was often not fulfilled; (iii) many visits were rated as poor quality; (iv) foster carers' evaluation of visits was more negative than that of both foster children and social workers; and (v) children who experienced poor‐quality visits and perceived less warmth and more criticism/rejection from their parents. These results highlight the need to improve contact visits by developing intervention strategies targeted at all those involved. [ABSTRACT FROM AUTHOR]

The goal of this study is to examine the suitability of three plants, Typha spp., Phragmites spp. and Iris pseudacorus, in a free-water surface constructed wetland created to treat eutrophic water from Lake Albufera (Valencia, Spain), a wetland of international importance. The growth, coverage and nutrient content of the three plants were studied, and chemical analyses were performed according to standard methods. The maximum standing crops measured for each plant were 1.9, 18.2 and 3.3 kg m, respectively, and their average nutrient concentrations were 2.1, 1.2 and 1.7 g P kg and 12.1, 11.7 and 10.1 g N kg, respectively. A multiple harvest of Iris pseudacorus revealed that the removal of nutrients could be increased up to 50% for N and 100% for P compared with a single harvest. Biomass decomposition assays showed high values for five-day biochemical oxygen demand (115-207 mg O g, depending on the plant and its age) and a substantial release of phosphorus, up to 100% of that contained in the biomass, highlighting the need to remove the litter fall. This study provides key aspects for vegetation selection and management (planting and harvesting) in a novel application of constructed wetlands to enhance water quality and biodiversity. [ABSTRACT FROM AUTHOR]

Groundwater pollution by nitrates induced by intensive agriculture and overexploitation of water in the Júcar River Basin District is a major concern. This work is a contribution to understanding the spatial and temporal distribution of nitrates in groundwater and the possible relationships between the presence of nitrates and contextual variables, such as rainfall, seepage and lithology. A space-time table of groundwater measurements of nitrate levels between 1969 and 2012 (41 hydrological years) in 6381 monitoring locations is used. First, a statistical analysis was performed to find correlations between nitrate concentrations and the contextual variables of yearly rainfall and recharge amounts evaluated by the PATRICAL model. A geostatistical simulation approach was then used to build a space-time model of nitrate concentrations, including calculation of experimental variograms and fitting of a theoretical model. The results of the variograms were used to infer the maximum spatial correlation distance and the maximum time range of temporal correlation for the same location. Sequential Gaussian simulation was selected instead of kriging for the purpose of declustering of data locations. Finally, yearly maps of average nitrate concentrations were generated. The results show that nitrate concentrations have increased steadily from the early 1970s and have stabilized since 2005. Contamination by nitrates occurs predominantly in agricultural areas, such as the plateau of La Mancha and the coastal plain. [ABSTRACT FROM AUTHOR]

Although several variables have been reported to be associated with behavioural problems in foster children, few studies have sought to establish more precisely the extent to which these variables may explain problematic behaviour. The main aim of this study is to determine the extent to which certain variables may predict behavioural problems shown by foster children. Participants included 104 foster children and their respective foster families. Multiple linear regression analysis revealed that the following variables predict behavioural problems in foster children: impulsivity/attention deficit in the child, level of burden in the foster carers, rigid or authoritarian parental discipline, and criticism/rejection by the foster parents. The model explained 46% of the variance in behaviour problems, with the greatest predictive power (29%) corresponding to the variable ‘impulsivity/attention deficit’. The results show that impulsivity/attention deficit is the most powerful predictor of behavioural problems in foster children. This is consistent with the findings of various studies that have reported an association between a lack of inhibitory control and problematic behaviour. [ABSTRACT FROM AUTHOR]

Los objetivos de este estudio fueron analizar: a) las relaciones afectivas en los acogimientos con familia ajena, desde la perspectiva de los acogedores y de los acogidos; b) el tipo de disciplina empleada por los acogedores; y c) las relaciones de estas variables con algunas características de los niños. Los participantes fueron 104 menores (56 niños y 48 niñas) y 86 familias acogedoras. El trabajo se realizó con la participación del Servicio de Protección de Menores y de las ICIF (Institución Colaboradora para la Integración Familiar). Los resultados mostraron: a) las relaciones afectivas fueron valoradas muy positivamente, alcanzando elevadas puntuaciones en afecto/comunicación y bajas en crítica/rechazo; b) el tipo de disciplina mayoritariamente utilizado por los acogedores fue el estilo inductivo; c) las relaciones afectivas se asociaron con la edad de los acogidos, la edad de inicio del acogimiento, el tiempo en acogimiento residencial, el autoconcepto y el rendimiento académico; y d) el tipo de disciplina de los acogedores se relacionó con el tiempo en acogimiento residencial y el autoconcepto.The aims of this research were to analyze: a) the affective relationships showed by families involved in foster care, from the perspectives of both caregivers and foster children; b) the type of discipline used by the caregivers involved; and c) these variables'' relationships with some characteristics of the children. Participants were 104 children (56 boys and 48 girls) and 86 foster families. This work was made possible thanks to the colaboration of the Spanish Child Protection Services and Foster Care Agencies. The results showed: a) affective relationships were rated very positively, reaching high scores on affect/communication, and low scores on criticism/rejection measures; b) the type of discipline mostly used by caregivers was the inductive style; c) affective relationships were associated with children''s age at the beginning of fostering, amount of time in residential care, children''s self-concept and school performance; and d) the type of discipline used by caregivers was related to the total time spent in residential care and children''s self-concept. [ABSTRACT FROM AUTHOR]

Aim: The purpose of this study was to determine the allelic and genotypic frequency distribution of the C34T mutation in the muscle isoform of the adenosine monophosphate deaminase 1 ( AMPD1) gene and of the missense substitution K153R in the myostatin ( GDF8) gene in one Spanish and two North African populations. Method: One sample of 98 individuals was genotyped from the South of Spain ( Alpujarra) and two samples from Morocco (77 Berbers and 78 Arabs). Results: The frequency of the AMPD1 C34T mutation was lower in Berbers (0.071) compared with the Alpujarra cohort (0.153, p == 0.018). The GDF8 K153R substitution showed little variability among the three cohorts. Conclusions: Studies with larger cohorts and other ethnic groups are needed to corroborate that there does not exist any major variability in the genotype distribution of genes associated with muscle phenotypes in the South-Eastern Mediterranean area. [ABSTRACT FROM AUTHOR]

Abstract: There is increasing evidence regarding the association between mitochondrial DNA (mtDNA) and aerobic capacity; however, whether mtDNA haplogroups are associated with the status of being an elite endurance athlete is more controversial. We compared the frequency distribution of mtDNA haplogroups among the following groups of Spanish (Caucasian) men: 102 elite endurance athletes (professional road cyclists, endurance runners), 51 elite power athletes (jumpers, throwers and sprinters), and 478 non-athletic controls. We observed a significant difference between endurance athletes and controls (Fisher exact test=17.89, P =0.015; Bonferroni''s significant threshold=0.017), yet not between power athletes and controls (Fisher exact test=47.99, P =0.381) or between endurance and power athletes (Fisher exact test=5.53, P =0.597). We observed that the V haplogroup was overrepresented in endurance athletes (15.7%) compared with controls (7.5%) (odds ratio: 2.284; 95% confidence interval: 1.237, 4.322). In conclusion, our findings overall support the idea that mtDNA variations could be among the numerous contributors to the status of being an elite endurance athlete, whereas no association was found with elite power athletic status. [Copyright &y& Elsevier]

Abstract: Background: This study was designed to compare two methods (direct measurement of exposure and quasi-induced exposure) for assessing the effect of age and sex on the risk of being involved in a car crash in Spain. Methods: Spanish crash rates (per 10,000,000 driver-km) for age and sex groups of drivers aged 18–64 years old were obtained for 2004–2007, using information from the Spanish General Traffic Office (census of reported car crashes) and the Spanish Household Survey on Alcohol and Drugs (estimate of the mean km driven for each car driver). The rate ratios estimated by direct exposure estimates were compared to those obtained with the quasi-induced exposure method, which compares the age and sex of responsible and non-responsible drivers involved in the same clean collision (in which only one of the drivers committed a driving infraction). Results: Both methods detected an increased risk of involvement in a crash for the youngest (18–20 years) and the oldest drivers (60–64 years), compared to middle-aged drivers (45–49 years). However, the rate ratios obtained with the quasi-induced method for the youngest group (2.0 for men, 1.6 for women) were much lower than those obtained with crash rates (13.4 for men, 5.7 for women). Both methods detected a similar increase in the risk of involvement of male drivers compared to women in the youngest age group. This excess risk for men was maintained with increasing age up to 45–49 years when the quasi-induced method was used. However, direct comparisons of crash rates revealed an increased risk of involvement in women compared to men of the same age from 25–29 years onward. Conclusions: Both direct measurement of driving exposure and the quasi-induced exposure method detected some well-known patterns of risk associated with driver''s age and sex. However, factors that could explain important differences between the two methods deserve attention, especially those related with the excess risk for the youngest drivers as well as sex-related risk. [Copyright &y& Elsevier]

The frequency of mitochondrial diseases (MD) has been scarcely documented, and only a few studies have reported data in certain specific geographical areas. In this study, we arranged a nationwide call in Spain to obtain a global estimate of the number of cases. A total of 3274 cases from 49 Spanish provinces were reported by 39 centres. Excluding duplicated and unsolved cases, 2761 patients harbouring pathogenic mutations in 140 genes were recruited between 1990 and 2020. A total of 508 patients exhibited mutations in nuclear DNA genes (75% paediatric patients) and 1105 in mitochondrial DNA genes (33% paediatric patients). A further 1148 cases harboured mutations in the MT-RNR1 gene (56% paediatric patients). The number of reported cases secondary to nuclear DNA mutations increased in 2014, owing to the implementation of next-generation sequencing technologies. Between 2014 and 2020, excepting MT-RNR1 cases, the incidence was 6.34 (95% CI: 5.71–6.97) cases per million inhabitants at the paediatric age and 1.36 (95% CI: 1.22–1.50) for adults. In conclusion, this is the first study to report nationwide epidemiological data for MD in Spain. The lack of identification of a remarkable number of mitochondrial genes necessitates the systematic application of high-throughput technologies in the routine diagnosis of MD. [ABSTRACT FROM AUTHOR]

Objective: To determine how the number of passengers, their age and their sex influence the risk of different types of Spanish drivers causing a collision between two or more cars.Methods: We selected, from the Spanish database of traffic crashes resulting in personal injuries or death, those collisions between two or more cars that occurred between 1990 and 1999 in which only one of the involved drivers committed a driving infraction. These drivers were considered the cases; non-infractor drivers were considered their matched controls. We collected information on the number, age and sex of the passengers in each vehicle, along with some potential confounding variables of the drivers and the vehicles involved. Crude and adjusted odds ratios were calculated for the main categories of driver and passenger.Results: A protective effect for the presence of passengers was detected (adjusted odds ratio: 0.69; 95% CI: 0.67–0.70). The protective effect was higher for drivers aged more than 45 years and lower for the youngest drivers (<24 years old). The strongest association was observed for female passengers who accompanied male drivers. The protective effect was lower for passengers older than 64 years.Conclusion: Our results suggest that drivers are less likely to cause a car collision between two or more cars that results in personal injuries or death when they are accompanied by passengers, regardless of driver or passenger characteristics. [Copyright &y& Elsevier]

This paper describes the results of a study of pollutant emissions by road traffic in Spain during the period 1988–1999. The study has covered two main phases: input data compilation and program execution (COPERT III).The first has been conditioned by the requirements imposed by the software in terms of de-aggregated data, which were not available at first, and required estimation. Adequate models and algorithms were developed, establishing different hypotheses based on statistical criteria and on current literature. They provided the input data for COPERT III and constitute a result in themselves, offering reliable estimations on number of vehicles and other aspects.The final result of the study has been the estimates of the evolution of pollutant emissions during the period of study. A series for each particular pollutant has been obtained.Based on these results, the effects of the different regulations introduced and of the increase of mobility during the period can be observed qualitatively and quantitatively. Vehicle renewal, more strict regulation of fuel composition and of vehicle emissions have significantly reduced local, sulphur and lead-compound emissions, while mainly due to the increase in mobility, a sustained growth in global emissions has taken place. [Copyright &y& Elsevier]

PURPOSE: To assess the strength of association of main driver-dependent risk factors with the risk of causing a collision between vehicles in Spain, from 1990 to 1999.METHODS: The data for this paired-by-collision, case-control study were obtained from the Spanish Direccio´n General de Tra´fico traffic crash database. The study included all 220,284 collisions involving two or more vehicles with four or more wheels, in which only one of the drivers involved committed an infraction. Infractor drivers comprised the case group; noninfractor drivers involved in the same collision were their corresponding paired controls.RESULTS: All driver-dependent factors were associated with the risk of causing a collision. The highest adjusted odds ratio estimates were obtained for sleepiness (64.35; CI, 45.12–91.79), inappropriate speed (28.33; CI, 26.37–30.44), and driving under the influence of alcohol with a positive breath test (22.32; CI, 19.64–25.37). An increase in the number of years in possession of a driving license showed a protective effect, albeit the strength of the effect decreased as age increased.CONCLUSIONS: Our results emphasize the urgent need to implement strategies aimed mainly at controlling speeding, sleepiness, and alcohol consumption before driving—the main driver-dependent risk factors for causing a vehicle collision. [Copyright &y& Elsevier]

Background. There is a need for solid evidence of the relative advantages of universal vs. selective screening for gestational diabetes mellitus. Our study of a broad obstetric population determines the positive predictive value of the 50-g oral glucose challenge test for screening in the presence and absence of classical gestational diabetes risk factors. Methods. A retrospective cohort study was carried out with a total of 2,574 pregnant women. Clinical information was obtained from hospital records and each patient's medical history, and gestational diabetes risk factors were quantified for each pregnant woman. The positive predictive value of a screen was determined with respect to the number of risk factors. Results. Age 30 or over, family history of diabetes, obesity (BMI ≥27) and previous fetal macrosomia were established as the most frequent risk factors. Just over half (54.2%) of our population presented one or more risk factors. Screening covered 75% of the population, and was positive in 15% of the cases. Diagnosis was confirmed in 64 cases, 57 of them at risk, and seven with no risk factors. We obtained an overall positive predictive value of 21.8% (CI 17.3–27.0). This figure increases with the number of risk factors, from 12% for the women with no risk factors, to 40% for those presenting three or more risk factors. Conclusions. A selective screening program that takes into account the clinical background and characteristics of each pregnant woman allows a high yield of true positives while reducing the possible undesirable effects associated with false positives. [ABSTRACT FROM AUTHOR]

Assesses the diet-smoking relationship in a sample of Spanish employees. Information on smokers consumption of less healthy diet; Use of multiple logistic regression models; Categories of food items consumed by smokers and non-smokers; Comparison of food intake.

In this study, a backpack-mounted 3D mobile scanning system and a fixed-wing drone (UAV) have been used to register terrain data on the same space. The study area is part of the ancient underground cellars in the Duero Basin. The aim of this work is to characterise the state of the roofs of these wine cellars by obtaining digital surface models (DSM) using the previously mentioned systems to detect any possible cases of collapse, using four geomatic products obtained with these systems. The results obtained from the process offer sufficient quality to generate valid DSMs in the study area or in a similar area. One limitation of the DSMs generated by backpack MMS is that the outcome depends on the distance of the points to the axis of the track and on the irregularities in the terrain. Specific parameters have been studied, such as the measuring distance from the scanning point in the laser scanner, the angle of incidence with regard to the ground, the surface vegetation, and any irregularities in the terrain. The registration speed and the high definition of the terrain offered by these systems produce a model that can be used to select the correct conservation priorities for this unique space. [ABSTRACT FROM AUTHOR]

The Water Framework Directive 2000/60/EC implemented by the European Union established as the main objectives to achieve a "good ecological and chemical status" of the surface water and a "good quantitative and chemical status" of groundwater bodies. One of the major pressures affecting water bodies comes from the use of pesticides and their potential presence in the water ecosystems. For this purpose, the reliable determination of pesticides and their transformation products (TPs) in natural waters (both surface and groundwater) is required. The high number of compounds potentially reaching the aquatic environment makes extraordinary difficult, if not impossible, to investigate all these compounds even using the most powerful analytical techniques. Among these, liquid chromatography coupled to high-resolution mass spectrometry is emphasized due to its strong potential for detection and identification of many organic contaminants thanks to the accurate-mass full spectrum acquisition data. This work focuses on wide-scope screening of many pesticides and their TPs in surface water and groundwater samples, collected between March and May 2017, in the Júcar River Hydrographical Basin, Spain. For this purpose, a home-made database containing more than 500 pesticides and TPs was employed. Analyses performed by liquid chromatography coupled to quadrupole-time of flight mass spectrometry (LC-QTOF MS) allowed the identification of up to 27 pesticides and 6 TPs. The most detected compounds in groundwater were the herbicides atrazine, simazine, terbuthylazine, and their TPs (atrazine-desethyl, terbumeton-desethyl and terbuthylazine-desethyl). Regarding surface water, the fungicides carbendazim, thiabendazole and imazalil, the herbicide terbutryn and the TP terbumeton-desethyl were also detected. These results illustrate the wide use of these compounds (in the present or in the recent past) in the area under study and the vulnerability of the water bodies, and are in accordance with previous findings in other water bodies of the different Spanish Hydrographic systems. Image 1 • High resolution mass spectrometry wide-scope screening of pesticides in water. • 27 pesticides and 6 transformation products were found in water samples. • Some compounds not included in routine target quantitative methods were identified. • Screening methodology was validated for 20 compounds commonly found in water. • Triazines and transformation products were the most frequently identified. [ABSTRACT FROM AUTHOR]