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• Remote sensing was used to monitor plateau wetland ecological degradation. • A composite wetland degradation index was constructed to assess wetland degradation quantitatively. • We analyzed ecological degradation process with three administrative levels. The Zoige Plateau Wetland is the largest high-altitude swamp wetland in China. It plays a key role in ecological balance and the global change. Climate change and improper utilization have consequently resulted in decreased wetland area, disrupted ecosystem structure, and wetland function degradation and function loss. The Zoige Plateau Wetland thus faces severe ecological degradation problems. In this study, selecting the Zoige Plateau Wetland as the study area, remote sensing was used to track the ecological degradation process during 2000–2015 from three aspects (area degradation, structure degradation and function degradation) and at three administrative levels (study area, county and key township). To assess the wetland degradation quantitatively, an analytic hierarchy process (AHP) was used to construct a composite wetland degradation index based on five indicators: wetland area change rate, landscape fractal dimension, landscape fragmentation, vegetation biomass and vegetation coverage. The results showed the following. (1) In terms of area change rate, the total wetland area had continuously decreased during 2000–2015 compared to that in the 1990s, and 2010 was the most significant. The frequency of negative change in the wetland area reached 87.5% in all four counties and across four time periods (2000, 2005, 2010 and 2015), and 85% at the township level. At the spatial scale, Hongyuan County had the smallest wetland area change rate. (2) In terms of structure change, the variations in landscape fractal dimension and landscape fragmentation generally exhibited similar trends at different levels. Specifically, the ecosystem structure was seriously affected in 2000, then gradually recovered in 2005 and 2010, and was again under aggravated interference in 2015. (3) In terms of function change, the above-ground biomass yield in the northeastern region was higher than that in the southern region. A low value was detected in 2000, and then the value increased and remained essentially the same in 2005 and 2010. However, the value decreased in 2015, indicating deteriorated vegetation condition. The vegetation coverage in the study area remained steady, without deterioration in a particular year. (4) In terms of the whole study area, the wetland degradation grades in the four periods were mild (2000), moderate (2005), mild (2010) and mild (2015). In brief, the wetland degradation was the most severe in 2005. Over the 2000–2015 period, the spatial degradation pattern of the Zoige Plateau Wetland progressed from the northeast to the southwest. The model built in this study could be widely applicable. And this study has also some reference value for monitoring and management of wetland degradation by remote sensing. [ABSTRACT FROM AUTHOR]

Background: MMPs/TIMPs system is well known to play important roles in pressure overloadinduced cardiac remodeling, and Amlodipine and Atorvastatin have been showed to exert favourable protective effects on cardiovascular disease, however, it is not clear whether Amlodipine and Atorvastatin can improve hypertensive cardiac remodeling and whether the MMPs/TIMPs system is involved. The present study aims to answer these questions. Methods: 36 weeks old male spontaneous hypertension (SHR) rats were randomly divided into four groups: 1). SHR control group, 2). Amlodipine alone (10 mg/kg/d) group, 3). Atorvastatin alone (10 mg/kg/d) group, 4).Combination of Amlodipine and Atorvastatin (10 mg/kg/d for each) group. Same gender, weight and age of Wistar-Kyoto (WKY) rats with normal blood pressure were used as normal control. Drugs were administered by oral gavage over 12 weeks. The blood pressure and left ventricle mass index were measured. Enzyme activity of MMP-2 and MMP-9 was assessed with Gelatin zymography. MMP-2, MMP-9, TIMP-1 and TIMP-2 mRNA and protein expression was studied by RT-PCR and Western blot. Single factor ANOVA and LSD-t test were used in statistical analysis. Results: Treatment with Amlodipine alone or combination with atorvastatin significantly decreased blood pressure, left ventricle mass index in SHR rats (P < 0.05 for both). Compared with WKY rats, the myocardial levels of MMP-2, MMP-9 mRNA, protein and enzyme activity were significantly increased (P<0.05). Amlodipine alone, Atorvastatin alone, and combination of the two all reduced MMP-2 and MMP-9 mRNA, protein and enzyme activity, with the best effects seen in the combination. Compared with WKY rats, the myocardial levels of TIMP-1 mRNA and protein were significantly increased (P<0.05), however, there was no difference in levels of TIMP-2. Neither Amlodipine alone, Atorvastatin alone, nor combination of the two drugs significantly affect the expression of TIMP-1 or TIMP- 2. Conclusion: Amlodipine and Atorvastatin could improve ventricular remodeling in SHR rats through intervention with the imbalance of MMP-2/TIMP-2 and MMP-9/TIMP-1 system. [ABSTRACT FROM AUTHOR]

Grassland vegetation growth directly reflects plant growth conditions, and growth processes are an important component of ecological status assessments of grasslands and can provide timely guidance for agricultural production. In this study, the Xilingol Grassland in Inner Mongolia was used as the study area, and a monitoring indicator system for the remote sensing of grassland vegetation growth was established based on 16 days of Moderate Resolution Imaging Spectroradiometer (MODIS) data and ground sampling data, which were used to assess the suitability of the indicator system. A monitoring indicator system for the remote sensing of grassland vegetation that included the modified growth index (MGI)-normalized difference vegetation index (NDVI), MGI-enhanced vegetation index (EVI), growth index (GI)-NDVI, and GI-EVI was established by using the year 2000 as the base year, two vegetation indices and difference and normalized difference methods. A model for estimating the ground growth (g) was then constructed by using expert opinion scoring and the Analytic Hierarchy Process (AHP) to determine the weights of vegetation coverage (c), height (h), and yield (y) in the ground plots, with the model calculated as follows:g = 0.2543c + 0.1848 h + 0.5609y. Additionally, the ground growth value was calculated according to the ground growth model, and the values obtained from the remote-sensing indicators in the corresponding region were subjected to a correlation analysis based on this partition. The remote-sensing growth indices suitable for temperate steppe, meadow steppe, and desert steppe regions were GI-EVI, MGI-NDVI, and GI-NDVI, respectively. Finally, vegetation growth in the Xilingol Grassland was evaluated using the optimal remote-sensing GI for each area, and the results indicated that the areas with the greatest growth improvement occurred in the temperate steppe region followed by the meadow steppe region, whereas vegetation growth improvement was insignificant in the desert steppe region. The results of this study have important significance for the economic development and ecological environmental improvement of pastoral and semi-pastoral regions and can be used to determine the optimal use and scientific management of grasslands. [ABSTRACT FROM PUBLISHER]

Desertification is treated as an important and critical environmental hazard. In the face of increasingly serious grassland desertification, China has made great efforts to combat desertification and a series of key national ecological projects has been launched. However, accurate, timely, and effective monitoring and assessment are required to determine whether these projects work well. The Horqin sandy land represents the largest area of sandy land in China. In this article, the Naiman and Ongniud Banners were studied because these contain the main desertified grassland in Horqin. Next, a desertification classification and grading system was designed for the Horqin sandy land after conducting fieldwork. Based on spectral mixture analysis (SMA) and decision-tree methods, we interpreted Landsat Thematic Mapper/Enhanced Thematic Mapper Plus/Operational Land Imager (TM/ETM+/OLI) images of the study area from four years: 1985, 1992, 2001, and 2013. Overall, the following results were obtained. The total area of desertified grassland in the Naiman and Ongniud Banners increased from 5979 km2in 1985 to 9195 km2in 1992 (an increase of 53.79%) and then decreased to 7828 km2in 2001 and to 6023 km2in 2013. The changes in the areas of desertified grassland with various degrees of desertification displayed the same trends as that of the total desertified grassland area. The severely desertified grassland expanded from 1872 km2in 1985 to 3723 km2in 1992 before shrinking to 2189 km2in 2013. The annual rates of expansion of desertified grassland during the periods 1985–1992, 1992–2001, and 2001–2013 were 7.68%, −1.65%, and −1.92%, respectively, and the corresponding expansion rates of severely desertified grassland were 14.12%, −3.48%, and −1.19%, respectively. Both the desertified grasslands and the areas with various degrees of desertification displayed significant expansion during the period 1985–1992. Since 1992, this trend has reduced. During the study period, the changes in temperature and precipitation did not benefit the reversal of grassland sandy desertification. Furthermore, the growing population and expansion of livestock production and farming inhibited such reversal. However, the results presented in this article suggest that a reversal in grassland sandy desertification has been occurring since 1992. The results indicate that ecological engineering measures have helped reverse desertification and have promoted the restoration of grassland vegetation. [ABSTRACT FROM PUBLISHER]

Grassland is not only an important landscape of the Beijing–Tianjin sandstorm source control project area, but also a significant object of the Beijing–Tianjin sandstorm source control project. By taking the situation in 2000 as the base of comparison and using the established grassland vegetation growth model, the monitoring and evaluation of grassland vegetation dynamic variation in the project area from 2000 to 2010 was conducted based on MODIS 16 days NDVI data. The conclusions are as follows: (1) The comparative result of average growth between each year from 2001 to 2010 and the base year was on the good side in general; the grassland growth was good both in the early and later periods of grassland growth peak season than in the first years of the project implementation, indicating that the implementation of the Beijing–Tianjin sandstorm source project has significantly improved the growth conditions of grassland vegetation; (2) With regard to the annual dynamic variation of grassland growth, the area proportions of the grasslands, of which the average grassland growth was on the good side, fluctuated and increased slightly with the time changes in general. The area proportions of the grasslands, of which the average grassland growth was on the bad side, fluctuated and decreased in general. The area proportions of the grasslands with normal growth showed an increasing overall trend; (3) From the regional perceptive on four zones, including the northern arid grassland desertification control zone, Hunshandake sandy land control zone, the farming-pastoral area of desertified land control zone, and the water conservation zone of Yanshan hills and mountains, except that the grassland growth in the farming-pastoral area of desertified land control zone was bad, the average growth of other three zones was good each year from 2001 to 2010 compared with the base year. (4) In respect of space, the regions with big grassland growth variation in the project area were concentrated in the western and eastern sections of the northern arid grassland desertification control zone and the western section of Hunshandake sandy land control zone. The grassland growth variation in the water conservation zone of Yanshan hills and mountains and the farming-pastoral area of desertified land control zone were relatively stable. On one hand, the conclusions of this paper can evaluate the effectiveness of the project control, on the other hand, it can also provide scientific basics to grassland management departments, facilitate the rational utilization of grassland, and preserve the regional ecological balance. [ABSTRACT FROM AUTHOR]

Facing the worsening degradation of grasslands, state and local governments in China have implemented a series of ecological protection projects. Ningxia Hui Autonomous Region was the first province in China to implement a region-wide grazing ban, the effect of which has become contentious at all levels of government and a topic of public concern. The change of grassland desertification is the most direct indicator of the grazing ban’s effect. This paper chooses Yanchi County in Ningxia as the study area to analyze the grassland desertification situation. Based on a series of Landsat TM/ETM+ images, field observations and expert review, a Ningxia grassland desertification classification and grading system was constructed. Then, spectral mixture analysis (SMA) and a decision-tree method were used to interpret images of the study area from 4 years: 1993, 2000, 2006, and 2011. The following results were obtained: the area of desertified grassland decreased gradually from 4142\;\km^2 in 1993 to 3695\;\km^2 in 2011, a decrease of 10.80%. The severity of desertification also declined as the area of severely desertified grassland gradually decreased to 324\;\km^2 in 2011 from 1093\;\km^2 in 1993, a decrease of 70.34%. The annual reduction rate of the desertified grassland area reached its peak during the period 2000–2006. In particular, the areas of severely desertified grassland declined by 8.86% annually. In a situation of declining rainfall, human factors (such as ecological protection policy) have become a major cause of ongoing grassland desertification reversal and restoration of grassland vegetation. [ABSTRACT FROM PUBLISHER]

It is critical to understanding grassland biomass and its dynamics to study regional carbon cycles and the sustainable use of grassland resources. In this study, we estimated aboveground biomass (AGB) and its spatio-temporal pattern for Inner Mongolia’s grassland between 2001 and 2011 using field samples, Moderate Resolution Imaging Spectroradiometer normalized difference vegetation index (MODIS-NDVI) time series data, and statistical models based on the relationship between NDVI and AGB. We also explored possible relationships between the spatio-temporal pattern of AGB and climatic factors. The following results were obtained: (1) AGB averaged 19.1 Tg C (1 Tg = 1012 g) over a total area of 66.01 × 104 km2between 2001 and 2011 and experienced a general fluctuation (coefficient of variation = 9.43%), with no significant trend over time (R2 = 0.05,p > 0.05). (2) The mean AGB density was 28.9 g C m−2 over the whole study area during the 11 year period, and it decreased from the northeastern part of the grassland to the southwestern part, exhibiting large spatial heterogeneity. (3) The AGB variation over the 11 year period was closely coupled with the pattern of precipitation from January to July, but we did not find a significant relationship between AGB and the corresponding temperature changes. Precipitation was also an important factor in the spatial pattern of AGB over the study area (R2 = 0.41,p< 0.001), while temperature seemed to be a minor factor (R2 = 0.14,p< 0.001). A moisture index that combined the effects of precipitation and temperature explained more variation in AGB than did precipitation alone (R2 = 0.45,p< 0.001). Our findings suggest that establishing separate statistical models for different vegetation conditions may reduce the uncertainty of AGB estimation on a large spatial scale. This study provides support for grassland administration for livestock production and the assessment of carbon storage in Inner Mongolia. [ABSTRACT FROM PUBLISHER]

Temperature and precipitation are considered to be the most important indicators affecting the green-up date. Sensitivity of the green-up date to temperature and precipitation is considered to be one of the key indicators to characterize the response of terrestrial ecosystems to climate change. We selected the main grassland types for analysis, including temperate steppe, temperate meadow steppe, upland meadow, and lowland meadow. This study investigates the variation in key meteorological indicators (daily maximum temperature (Tmax), daily minimum temperature (Tmin), and precipitation) between 2001 and 2018. We then examined the partial correlation and sensitivity of green-up date (GUD) to Tmax, Tmin, and precipitation. Our analysis indicated that the average GUD across the whole area was DOY 113. The mean GUD trend was −3.1 days/decade and the 25% region advanced significantly. Tmax and Tmin mainly showed a decreasing trend in winter (p > 0.05). In spring, Tmax mainly showed an increasing trend (p > 0.05) and Tmin a decreasing trend (p > 0.05). Precipitation showed no significant (p > 0.05) change trend and the trend range was ±10 mm/decade. For temperate steppe, the increase in Tmin in March promotes green-up (27.3%, the proportion of significant pixels), with a sensitivity of −0.17 days/°C. In addition, precipitation in April also promotes green-up (21.7%), with a sensitivity of −0.32 days/mm. The GUDs of temperate meadow steppe (73.9%), lowland meadow (65.9%), and upland meadow (22.1%) were mainly affected by Tmin in March, with sensitivities of −0.15 days/°C, −0.13 days/°C, and −0.14 days/°C, respectively. The results of this study reveal the response of vegetation to climate warming and contribute to improving the prediction of ecological changes as temperatures increase in the future. [ABSTRACT FROM AUTHOR]

Abstract: CdTe and ZnS quantum dots sensitized TiO2 nanotube array photoelectrodes were prepared by depositing CdTe and ZnS QDs on the tube walls of the self-organized TiO2 NTs using successive ionic layer adsorption and reaction (SILAR) technique. The deposition of CdTe and ZnS on the upper and inner surface of the TiO2 NTs was confirmed by field emission scanning electron (FE-SEM) and transmission electron microscopes (TEM). The obtained results indicated that TiO2 NTs photoelectrodes sensitized by CdTe quantum dots for 5 cycles exhibited excellent photoelectrochemical properties, with an open-circuit voltage of 0.95V and a short circuit current density of 11.15mAcm−2, and ZnS coating protected the photoelectrodes against photocorrosion. [Copyright &y& Elsevier]

Abstract: The Ag and CdS nanoparticles co-sensitization of TiO2 nanotubes (CdS–Ag/TiO2 NTs) were prepared by successive ionic layer adsorption and reaction (SILAR) technique. The phase composition, morphology and optical property were characterized by the X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and UV–vis diffusion reflection spectroscopy (DRS). The co-modification of Ag and CdS nanoparticles expanded the photoresponse range of TiO2 NTs from ultraviolet region to 668.7nm, and the CdS–Ag/TiO2 NTs prepared by SILAR deposition of 5 cycles exhibited higher visible photocurrent and stability against photocorrosion. The detailed electrons transfer mechanism of CdS–Ag/TiO2 NTs was proposed, and photocatalytic activity toward degradation of methyl orange (MO) under visible-light irradiation was also investigated. [Copyright &y& Elsevier]

Abstract: Ordered anatase TiO2 nanotubes (TiO2 NTs) on Ti substrate were synthesized by electrochemical anodization and subsequently vapor-thermal treatment. Ag nanoparticles were decorated on TiO2 NTs by successive ionic layer adsorption and reaction (SILAR) technique. Raman spectroscopy, X-ray absorption near edge spectroscopy (XANES), X-ray diffraction (XRD), UV–vis diffuse reflectance spectroscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used for the characterization of surface morphology, phase composition, and microstructure of the original TiO2 NTs, the vapor-thermally treated TiO2 NTs and the Ag nanoparticles decorated TiO2 NTs. The results indicate that vapor-thermal treatment favors to the transformation of amorphous TiO2 into anatase phase. Increasing the SILAR cycle times favors to increase the loaded amounts of Ag nanoparticles in TiO2 NTs. Ag nanoparticles are uniformly distributed in the TiO2 NTs, and the SILAR process does not damage the ordered tubular structure. A possible formation mechanism of Ag/TiO2 NTs has also been proposed. The photocatalytic results showed that the Ag nanoparticle modified TiO2 NTs largely enhanced the photocatalytic degradation of methyl orange under ultraviolet light irradiation. [Copyright &y& Elsevier]

Abstract: Nitrogen-doped titanium dioxide mesosponge was fabricated by transformation of TiO2 nanotube arrays using a facial solvothermal method. The structure, morphology and optical property were investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and UV–vis diffusion reflection spectroscopy (DRS). A possible formation mechanism of N-doped TiO2 mesosponge has been proposed. The photoelectrochemical results indicate that N-doped TiO2 mesosponge prepared in ethanol solution of ammonia exhibits much higher photocurrent densities and the optimal photocatalytic activity. [Copyright &y& Elsevier]

Abstract: Anatase titanium dioxide (TiO2) mesoporous microspheres with core–shell and hollow structure were successfully prepared on a large scale by a one-step template-free chemical vapor deposition method. The effects of various reaction conditions on the morphology, composition and structure of the products were investigated by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Brunauer–Emmett–Teller (BET) technique and photoluminescence (PL) method. The results indicate that the product near the source was composed of core–shell structure TiO2 microspheres with diameters from 3 to 5μm. With increasing the distance between the source materials and the substrate, the hollow TiO2 spheres with 1–2μm dominant the products. A localized Ostwald ripening can be use to explain the formation of core–shell and hollow structures, and the size of the initial TiO2 solid nanoparticles plays an important role in determining the evacuation manner of the solid in the ripening-induced hollowing process. The surface area of TiO2 hollow microspheres determined by the adsorption isotherms was measured to be 74.67m2/g. X-ray photoelectron spectroscopy (XPS) analysis revealed that the O–H peaks of hollow structures have a chemical shift compared with the core–shell structures. The optical property of the products was also discussed. [Copyright &y& Elsevier]

Abstract: Sb2O3 nanorod-bundles with length of about 4μm were fabricated in the presence of polyvinyl alcohol (PVA) by a simple hydrothermal method. The composition, morphology, microstructure and optical property of the as-prepared bundles were characterized by XRD, XPS, SEM, TEM and Raman spectrum. The results showed that the nanorod-bundles were composed of massive orthorhombic phase Sb2O3 nanorods grown along [001] direction. It was speculated that the nanorod-bundles developed through self-assembly of initially scattered nuclei into microdisks and subsequent oriented attachment process. PVA played a crucial role in the formation of Sb2O3 nanorod-bundles. [Copyright &y& Elsevier]

• The RSDI is suitable for monitoring aeolian desertification. • The areas with significant restoration (34.1%) exceeded those with significant deterioration (6%) in the NSPB. • In the areas with significant restoration, 57.4% of the land was mainly affected by human activities. The northern sand-prevention belt (NSPB) is the key area for sand control in China, and the various ecological projects conducted there are important to the Chinese strategy for ecological security. In this paper, a new remote sensing-based desertification index (RSDI) based on principal component analysis was constructed from four aspects of vegetation greenness, surface moisture, soil grain size, and surface radiation. The overall evaluation accuracy of the index was 89.2%, and the kappa coefficient was 0.80, indicating high sensitivity to different degrees of aeolian desertification and suitability for multiscale research. The coefficient of variation, Mann–Kendall test, Theil–Sen median trend analysis, and residual analysis were used to analyze the spatiotemporal changes and driving forces of the RSDI in the NSPB from 2000 to 2020. The RSDI was used to compare aeolian desertification in different subregions, land use types, and ecological project areas. The important results are as follows: (1) the trend of the average RSDI was downward, but it increased significantly in 2008–2009 and 2013–2014; (2) the RSDI was characterized by relatively high volatility in 28.9% and moderate volatility in 27.1% of the area; (3) the areas with significant restoration (34.1%) greatly exceeded those with significant deterioration (6%), whereas 59.9% of the total area was stable; and (4) within the area with significant restoration, 57.4% was primarily affected by human activities, and 42.4% was primarily affected by climate change; however, most of the area with significant deterioration (71.1%) was affected by human activities. In general, the degree of aeolian desertification in the NSPB has decreased in the past 20 years and its ecological quality has continued to recover. However, unreasonable human activities still need to be reduced, and the ecological management of areas under serious threat of desertification needs to be strengthened. [ABSTRACT FROM AUTHOR]

Northern China has been long threatened by aeolian desertification. In recent years, all levels of the Chinese government have performed a series of ecological protection and sand control projects. To grasp the implementation effects of these projects and adjust policies in time, it is necessary to understand the process of aeolian desertification quickly and accurately. Remote sensing technologies play an irreplaceable role in aeolian desertification monitoring. In this study, the Zhenglan Banner, which is in the hinterland of the Hunshandake Sandy Land, was considered as the research area. Based on unmanned aerial vehicle (UAV) images, ground survey data, and Landsat images called in Google Earth Engine (GEE), the aeolian desertified land (ADL) in 2000, 2004, 2010, 2015, and 2019 was extracted using spectral mixture analysis. A desertification index (DI) was constructed to evaluate the spatial and temporal dynamics of the ADL in the Zhenglan Banner. Finally, a residual analysis explored the driving forces of aeolian desertification. The results showed that (1) the ADL area in the Zhenglan Banner has been trending downwards over the past 20 years but rebounded from 2004 to 2010; (2) over the past 20 years, the area of slightly, moderately, and severely desertified land has decreased at annual rates of 0.4%, 2.7%, and 3.4%, respectively; (3) human activities had significantly positive and negative impacts on the aeolian desertification trend for 20.0% and 21.0% of the study area, respectively, but not for the rest. This paper explored new techniques for rapid aeolian desertification monitoring and is of great significance for controlling and managing aeolian desertification in this region. [ABSTRACT FROM AUTHOR]

The accumulation of heat and moderate precipitation are the primary factors that are used by grasslands to trigger a green-up date. The accumulated growing degree-days (AGDD) requirement over the preseason is an important indicator of the response of grassland spring phenology to climate change. This study adopted the Normalized Difference Phenology Index (NDPI), which derived from the Moderate Resolution Imaging Spectroradiometer (MODIS), to extract annual green-up dates in the Hulun Buir grassland in China between 2001–2015. Our analysis indicated that the range (standard deviation) and trend for the green-up date were DOY (day of year) 104 to DOY 144 (10.6 days) and −2.0 days per decade. Nine point two percent of the study area had significant (p < 0.05) changes in AGDD requirements. The partial correlations between the AGDD requirements and chilling days (67.04%, pixels proportion) were negative and significant (p < 0.05). The partial correlations between the AGDD requirement and precipitation (28.87%) were positive and significant (p < 0.05). Finally, the partial correlation between the AGDD requirement and insolation (97.65%) were positive and significant (p < 0.05). The results of this study could reveal the response of vegetation to climate warming and contribute to improving the phenological mechanism model of different grassland types in future research. [ABSTRACT FROM AUTHOR]

Land use/land cover change (LUCC) is the most direct driving force of landscape pattern change. The Zoige Plateau is a natural ecosystem with the largest high-altitude swamp wetland in China and its land use pattern has undergone great changes in recent years, but how the changes of each land use type affect the landscape pattern is uncertain. Here, we used the object-oriented method to extract land use information in 2015. Then, combined with land use data, the land use change characteristics from 2000 to 2015 were analyzed. We used the correlation analysis method to analyze the effects of land use changes on landscape pattern systematically. Three key conclusions were reached. (1) Land use information for the Zoige Plateau could be extracted with high accuracy by combining the object-oriented method and support vector machine (SVM). The overall accuracy was 93.2% and the Kappa coefficient was 0.889. (2) The comprehensive dynamic degree of land use was the highest from 2010 to 2015. From 2000 to 2015, the wetland area decreased the fastest because 57.05% of the wetlands were transferred out. Construction land increased the fastest, and the transferred in area from grassland and farmland were the main reason. (3) The effects of unused land, farmland, and construction land on the overall landscape pattern were stronger than that of the other types, among which farmland had the most significant impact (with a correlation coefficient of 0.959, p < 0.001). The change of unused land was the most highly significant factor associated with the landscape area pattern, and both the water body and unused land showed strong correlations with landscape shape pattern change. This suggested that the effects of land use types occupying a relatively small area on the landscape pattern were intensified. This study will provide guidance for the environmental management of local land resources and other natural ecosystem areas. [ABSTRACT FROM AUTHOR]

Titanium oxide is the most widely used material for photocatalytic applications due to its low cost and environmental friendliness. One of the grand challenges to improve its energy conversion efficiency is to utilize more visible light while inhibiting the recombination of photogenerated electrons and holes. A one‐step hydrosolvothermal method is used to obtain colored ultrafine nanowires of rutile and nanoparticles of anatase with edge dislocations, which induce broadened visible solar absorption (400–900 nm) and improve photocatalytic efficiency up to 1.8 times that of rutile or anatase without defects. Enhanced photocatalytic activity of these structures is demonstrated by photodegrading methylene blue measurements under simulated solar light irradiation. Results show the existence of Ti3+, induced by edge dislocations, and subsequent electronic band structure–property relationships. This work highlights a strategy for generating sufficient desired defects in TiO2 nanostructures, leading to broadened visible solar absorption and improved photocatalytic efficiency under visible light irradiation. [ABSTRACT FROM AUTHOR]

Knowledge about grassland biomass and its dynamics is critical for studying regional carbon cycles and for the sustainable use of grassland resources. In this study, we investigated the spatio-temporal variation of biomass in the Xilingol grasslands of northern China. Field-based biomass samples and MODIS time series data sets were used to establish two empirical models based on the relationship of the normalized difference vegetation index (NDVI) with above-ground biomass (AGB) as well as that of AGB with below-ground biomass (BGB). We further explored the climatic controls of these variations. Our results showed that the biomass averaged 99.01 Tg (1 Tg=1012 g) over a total area of 19.6×104 km2 and fluctuated with no significant trend from 2001 to 2012. The mean biomass density was 505.4 g/m2, with 62.6 g/m2 in AGB and 442.8 g/m2 in BGB, which generally decreased from northeast to southwest and exhibited a large spatial heterogeneity. The year-to-year AGB pattern was generally consistent with the inter-annual variation in the growing season precipitation (GSP), showing a robust positive correlation (R2=0.82, P<0.001), but an opposite coupled pattern was observed with the growing season temperature (GST) (R2=0.61, P=0.003). Climatic factors also affected the spatial distribution of AGB, which increased progressively with the GSP gradient (R2=0.76, P<0.0001) but decreased with an increasing GST (R2=0.70, P<0.0001). An improved moisture index that combined the effects of GST and GSP explained more variation in AGB than did precipitation alone (R2=0.81, P<0.0001). The relationship between AGB and GSP could be fit by a power function. This increasing slope of the GSP–AGB relationships along the GSP gradient may be partly explained by the GST–GSP spatial pattern in Xilingol. Our findings suggest that the relationships between climatic factors and AGB may be scale-dependent and that multi-scale studies and sufficient long-term field data are needed to examine the relationships between AGB and climatic factors. [ABSTRACT FROM AUTHOR]

An adaptive Fourier neural operator (AFNO)-transformer model was developed to retrieve land surface temperature (LST) data from infrared atmospheric sounding interferometer (IASI) observations. A weight selection scheme based on linearization of the radiative transfer equation was proposed to solve the hyperspectral data channel redundancy problem. The IASI brightness temperatures and Advanced Very High Resolution Radiometer onboard MetOp (AVHRR/MetOp) LST product were selected to construct the training and test datasets. The AFNO-transformer performed effective token mixing through self-attention and effectively solved the global convolution problem in the Fourier domain, which can better learn complex nonlinear equations and achieve time-series forecasting. The root mean square error indicated that the LST in Eastern Spain and North Africa could be retrieved with an error of less than 2.5 K compared with the AVHRR/MetOp LST product. Moreover, the validation results from other time period data showed that the retrieval accuracy of this model can be less than 3 K. The proposed model provides a novel approach for hyperspectral LST retrieval.

Background: This study sought to explore the mechanism of action of the micro ribonucleic acid (miR)-4291 in stabilizing atherosclerotic (AS) plaques., Methods: An AS model of apolipoprotein E-deficient (ApoE -/- ) mice fed a high-fat diet (HFD) was established. Oxidized low-density lipoprotein (ox-LDL) was used to induce an inflammatory response of RAW264.7 macrophages. The mice were divided into the normal diet (ND) + miR-4291 negative control (NC) group, the ND + miR-4291 mimic group, the HFD + miR-4291 NC group, and the HFD + miR-4291 mimic group. They were also classified into the miR-4291 NC group, the miR-4291 mimic group, the ox-LDL + miR-4291 NC group, and the ox-LDL + miR-4291 mimic group. The arterial plaque burden of the mice was assessed by hematoxylin-eosin staining and immunohistochemistry, and the expression of phosphorylated-extracellular signal-regulated kinase 2 (p-ERK2) and related proteins in the arterial plaques and RAW264.7 macrophages of the mice were detected by Western blotting., Results: Obvious plaques with massive macrophage infiltration were found in the aortic roots of the mice fed a HFD, and smooth muscle cells were found at the margin of the plaques. In the HFD + miR-4291 mimic group, the number of plaques and macrophages was significantly declined, but there were no significant changes in the smooth muscle cells compared to those in the HFD + miR-4291 NC group. The Western blot results showed that miR-4291 reduced the protein expression of p-ERK1-2, t-ERK1-2, TNF-α, MCP-1, MMP-1, MMP-3, and MMP-9 in the AS plaques and the ox-LDL-induced RAW264.7 macrophages of the mice fed a HFD., Conclusions: MiR-4291 reduced the expression of MMP-2/9 by inhibiting the activity of ERK2, which in turn increased the fibrous cap thickness and stabilized the vulnerable plaques in AS., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://atm.amegroups.com/article/view/10.21037/atm-22-5241/coif). The authors have no conflicts of interest to declare., (2022 Annals of Translational Medicine. All rights reserved.)

Jaundice is a detection index in many disease conditions commonly characterized by yellowish staining of the skin and mucous membranes. This work studies the postoperative care outcome in 1,246 patients (669 males and 577 females) with obstructive jaundice who underwent percutaneous transhepatic biliary drainage (PTBD). These patients were admitted to the interventional vascular surgery department of our hospital from February 2017 to February 2022. From the results, frequent wound re-dressing and maintenance of the drainage tube had significant positive influence on wound healing and patient recovery. The data also showed strict adherence by patients to the doctor's recommendation advising them to visit the interventional specialist care clinic in time for wound dressing change and drainage tube maintenance. As a result, there was no significant difference in wound allergy, exudation, redness and loosening among patients. A cross-sectional analysis of the effect of age on recovery revealed variations in the healing pattern (wound loosening and the redness) between patients of different ages although the relationship is not very clear due to the limited sample size. Efficient drainage tube maintenance promoted recovery and prevented the occurrence of related complications such as PTBD tube blockage and biliary tract infection. The establishment of the interventional specialist care clinic used in this study additionally ensures patients' safety, and the incidence of complications have been reduced drastically. These achievements are attributable to the implementation of regular dressing change, drainage tube maintenance and health education for patients with PTBD tube. These practices have also improved on the level of specialty in nursing practice, increased the professional value of nurses and better recognition by the society., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.., (Copyright © 2022 Yang, Qin, Mo, Xiang, Liu, Long and Xiang.)

High performance supercapacitor without binders has attracted wide attention as an energy storage device. In this work, novel NH 4 V 4 O 10 nanobelts were successfully synthesized and decorated into TiN nanotube arrays by a simple hydrothermal method. The as-prepared no-binder electrode hybrids exhibited excellent electrochemical performances with a specific capacitance of 749.0 F g -1 at 5 mV s -1 and a capacity retention of 85.7% after 200 cycles, which makes it an appealing candidate for electrode materials of supercapacitors., Competing Interests: There are no conflicts to declare., (This journal is © The Royal Society of Chemistry.)

BACKGROUND The classical dynamin family consists of dynamin 1, 2, and 3, which have different expression levels in different tissues to regulate cell membrane fission and endocytosis. Recent studies have reported increased expression of dynamins in human cancer, but their expression in hepatocellular carcinoma (HCC) remains to be determined. This study aimed to investigate the expression of dynamin 1, 2, and 3 in tissue sections of human HCC using quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry. MATERIAL AND METHODS The expression of dynamin 1, 2, and 3 were investigated in 192 cases of HCC and 14 paired samples of HCC and adjacent normal liver tissue by qRT-PCR and immunohistochemistry. The clinical significance of dynamin 1, 2, and 3 were determined by correlating their expression levels with patient clinicopathological factors and survival rates. Independent prognostic factors were determined using the Cox regression hazard model. RESULTS In tissue samples from 192 patients with HCC, the expression of dynamin 1, 2, and 3 were upregulated in 41.15%, 29.69%, and 8.33% of cases, respectively. Dynamin 1 had a significantly increased mRNA expression level in HCC compared with adjacent normal liver tissues and was significantly correlated with alpha fetoprotein (AFP) levels, T stage, and TNM stage. Only dynamin 1 expression was correlated with the reduced overall survival (OS), and was identified as an independent prognostic biomarker of human HCC. CONCLUSIONS Upregulation of dynamin 1 at the protein and mRNA level was an independent prognostic biomarker of reduced OS in patients with HCC.

Contrast-induced acute kidney injury (CI-AKI) is a severe complication caused by intravascular applied radial contrast media (CM). Pyroptosis is a lytic type of cell death inherently associated with inflammation response and the secretion of pro-inflammatory cytokines following caspase-1 activation. The aim of the present study was to investigate the protective effects of acetylbritannilactone (ABL) on iopromide (IOP)-induced acute renal failure and reveal the underlying mechanism. In vivo and in vitro, IOP treatment caused renal damage and elevated the caspase-1 (+) propidium iodide (PI) (+) cell count, interleukin (IL)-1β and IL-18 levels, lactate dehydrogenase (LDH) release, and the relative expression of nucleotide-binding domain, leucine-rich repeat containing protein 3 (NLRP3), apoptosis-associated speck-like protein (ASC), and gasdermin D (GSDMD), suggesting that IOP induces AKI via the activation of pyroptosis. Furthermore, the pretreatment of ABL partly mitigated the CI-AKI, development of pyroptosis, and subsequent kidney inflammation. These data revealed that ABL partially prevents renal dysfunction and reduces pyroptosis in CI-AKI, which may provide a therapeutic target for the treatment of CM-induced AKI., (© 2020 The Author(s).)

Since rural reforms in the 1980s, both the state and local governments of China have devoted great efforts to combating desertification through a number of eco-environmental restoration campaigns, resulting in burgeoning contention at all levels of government and sparking public concern. Monitoring and accurately assessing the statuses and trends of grassland desertification are important for developing effective restoration strategies. The Horqin Sandy Land (HSL), a very typical desertified grassland (DG) with better hydrothermal conditions among sandy lands in north China, was recently selected (1985-2013) to assess the spatiotemporal dynamic performances of grassland desertification before and after implementing restoration projects. Landsat images (TM/ETM+/OLI), field investigations and expert review were integrated to form a classification scheme for the HSL. Then, spectral mixture analysis and the decision-tree method were used to extract bare-sand ratios and vegetation cover fraction dynamics. A favourable phenomenon of DG was seen to be reversed in an accelerated pace during 2001-2013, despite challenge from both climatic and anthropogenic factors. However, overexploitation of grassland (especially for farming) and ground water for irrigation has led to remarkable decreases in the ground water level in recent decades, which should be highly concerning regarding the formulation of restoration campaigns in the sandy land.

Growing evidences suggest that there are close associations between anthocyanins and cardiac protection. However, little is known about the detailed roles of anthocyanins in regulating extracellular matrix (ECM) remodeling. Incubation of primary cultured fibroblasts with anthocyanins reduced both intracellular collagen expression and extracellular collagen secretion. Down-regulation of collagen production was also shown in infarcted cardiac tissues after permanent coronary artery ligation in mice treated with anthocyanins. The phosphorylation levels of Akt and/or P-38 were significantly increased by anthocyanins supplementation in primary cultured fibroblasts. Gelatin zymography analysis of matrix metalloproteinase-2 (MMP-2) activity in conditioned medium collected from fibroblasts demonstrated that anthocyanins treatment significantly reduced MMP-2 activity. These results demonstrated that anthocyanins play a role in mediating myocardial ECM remodeling and that the Akt/P-38 pathways mediate these protective effects on hearts.

Acute myocardial infarction (AMI) is the myocardial necrosis caused by coronary artery acute and persistent ischemia and hypoxia. Matrix metalloprotease-9 (MMP-9) plays an important role in a series of process of occurrence and development of AMI. Inflammatory reaction plays the key role in all kinds of damage factors in AMI. Apigenin (API) has effectively restrained the activity of MMP-9, anti-inflammatory and hepatic fat oxidizing properties. API significantly improved AMI of rats through inhibiting MMP-9 and inflammatory reactions in a few recent studies. Our investigation detected the infarct size of AMI rats, casein kinase (CK), the MB isoenzyme of creatine kinase (CK-MB) and lactate dehydrogenase (LDH) and cardiac troponin T (cTnT) activities in AMI rats were also analyzed with commercial kits. Additionally, Nuclear factor kappa B (NF-κB), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) levels of whole bloods of AMI rats were also detected using commercial kits. Next, MMP-9 protein of cardiac in AMI rats was measured with gelatin zymography assays. Finally, caspase-3 and caspase-9 activities in AMI rats were analyzed with commercial kits. In the present study, our work indicated API might significantly reduce the infarction size of AMI rat. It was shown that the treatment of API could decrease the expression of MMP-9 level and reduce the activities of NF-κB, TNF-α, IL-1β and IL-6 in AMI rats. Next, API treatment could reduce caspase-3 and caspase-9 activities and decrease cellular apoptosis of AMI rats. Our findings concluded that API ameliorates acute myocardial infarction of rats via inhibiting MMP-9 and inflammatory reactions.

Objective: Nicorandil, an opener of ATP-sensitive K+ channels, was used to treat angina in patients with coronary artery disease. In this study, we aim to investigate the cardioprotective effects of single oral dose of nicorandil in patients undergoing selective percutaneous coronary intervention (PCI)., Methods: One hundred and thirty-eight patients with acute coronary syndrome undergoing PCI from July 2011 to October 2012 were randomly divided into control group (group 1, n = 47), 10 mg oral nicorandil group (group 2, n = 45), and 20 mg oral nicorandil group (group 3, n = 46) about 2 hours before procedure, respectively. Cardiac troponin I (cTnI) levels were determined at 20 ~ 24 hours after PCI., Results: There was a significant difference in the rate of any cTnI elevation among the three groups (group 1: 36.17%, group 2: 20.00%, group 3: 15.22%, p = 0.0176). With respect to the frequency of cTnI elevation ≥ 3 and 5 × the upper limit of normal (ULN), there also had statistical difference among the three groups (17.02% in group 1, 8.89% in group 2, and 4.35% in group 3, respectively for cTnI elevation ≥ 3 × ULN, p = 0.0428; 12.77% in group 1, 6.67% in group 2, and 2.17% in group 3, respectively, for cTnI elevation ≥ 5 × ULN, p = 0.0487). Logistic regression analysis showed that LVEF (OR = 0.915, 95% CI = 0.853-0.981) and the use of nicorandil (OR = 0.516, 95% CI = 0.267-0.996) before PCI were independent protective factors of myocardial injury., Conclusion: Single oral dose of nicorandil (10 mg, 20 mg) 2 hours before the PCI procedure could decrease the incidence of peri-procedure myocardial injury and PCI-related myocardial infarction.

High-density CuS nanoparticle nanowire (NPNW) arrays were successfully synthesized at room temperature by a simple paired cell method. The as-prepared nanowire arrays were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive spectroscopy (EDS) and transmission electron microscopy (TEM). The results indicate that the nanowire diameter is dependent on the pore size of the used ordered porous anodic alumina (OPAA) template and larger than the corresponding pore diameter of the template due to the corrosion effect of Na2S solution on the template. The nanowire is composed of CuS nanoparticles with hexagonal structure. When the reaction time is long enough, the nanowire is solid and composed of nearly spherical CuS nanoparticles. When the reaction time is short, only middle part of the nanowire is solid and composed of nearly spherical CuS nanoparticles, however, the tops are hollow and mainly composed of flake-like nanoparticles. The formation mechanism of CuS nanoparticle nanowires was proposed to be a heterogeneous nucleation, coalescence, aggregation and filling process.