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The aim of the article is to analyse the relationship between company growth, measured as an increase in Earnings Per Share (EPS) in 3- and 5-year periods, and companies’ financial condition, measured using the Altman z-Score (AS) model. The study was carried out on the example of companies included in the WIG Index and Warsaw Stock Exchange Index (in Polish: Warszawski Indeks Giełdowy – WIG) Environmental, Social, and Governance (ESG) between 2013 and 2020. Furthermore, among the companies included in the WIG index, companies belonging to the logistics industry were distinguished. An analysis of linear and panel relationships was used to verify the nature of the relationships between the variables taken into account. The z-Altman index was found to have a positive effect on company growth in a 3-year period for companies from the transport and logistics industry and all companies included in the WIG ESG index. Regarding company growth over the longer 5-year period, the influence of the z-Altman index on growth was not observed. Therefore, the results for companies in the WIG index show that for company growth in both the 3- and 5-year periods, the financial and economic condition of a company, measured by the z-Altman index, has no impact on the size of this growth, which was also confirmed by panel models.

The aim of the research was to find a zirconia treatment method that would reduce or minimize the transformation from the tetragonal phase to the monoclinic phase. Background: Yttria-stabilized zirconia is increasingly chosen for the base of permanent prosthetic restorations. To achieve a good bond between the prosthetic cup and the veneer material, the material must be treated to achieve surface development. This is a mechanical process, during which an unfavorable transformation from the tetragonal into the monoclinic phase takes place, which leads to the weakening of the internal structure of zirconium dioxide, and later damages the prosthetic restoration. Methods: The tested material consisted of cylindrical samples of 3Y-TZP CeramillZi zirconium oxide, which were sintered after cutting out from the block. After sintering, the samples were subjected to the following types of processing: laser structuring, chemical etching and plasma etching. After the surface treatments, the samples were subjected to diffraction tests to determine the phase composition. Next, the wettability was tested to determine the surface free energy. Results: On the basis of the conducted tests, it was noticed that the applied treatments caused a phase transformation from the tetragonal to the monoclinic phase. After the process of chemical etching, the range of the monoclinic phase for the sample was 5%; after plasma etching, it was 8%, and after laser structuring, it was 2%. In addition, post-surface free energy studies have shown that zirconia is wetted better with an apolar than a polar liquid. Conclusions: The obtained results indicate that the transformation was minimized with the treatments we applied; that is why they are called non-invasive methods. According to the literature data, depending on the parameters of the sandblasting process, the percentage of the monoclinic phase in the treated surfaces ranges from 22% to 52%, which confirms the above-mentioned conclusion.

Energy is regarded as a crucial facilitator of social and economic advancement, and, consequently, sustainable development. The concept of sustainable energy development has evolved to become a significant political objective addressed by governments worldwide. All sectors of the economy, including agriculture, require stimulation, which should be triggered by linkages and structural changes contributing to qualitative and quantitative progress. Agriculture has a substantial impact on the environmental footprint, playing a pivotal role in causing climate change. The objective of this article is to address the research gap concerning the monitoring of sustainable development in the energy and agricultural sectors within the European Union. The assessment of sustainability is a complex process since it is a multidisciplinary field of study with practical implications. The progress of sustainable development in the energy and agricultural sectors was evaluated through a comprehensive analysis of relevant literature and statistical data obtained from the Eurostat database and the Research Institute of Organic Agriculture FiBL. The analysis encompasses the period between 2015 and 2022. The article employs the taxonomic method, specifically the linear ordering method (standardised sum method), which enables the construction of a synthetic measure. This approach enabled the creation of rankings and comparisons between European Union countries. The studies show that in the European Union, sustainable energy development and sustainable agriculture show significant territorial differentiation. The sustainable energy measures in the countries with the highest scores (Estonia, Sweden, Finland, Austria) were 2–3 times higher than in the countries with the lowest scores (Cyprus, Belgium, Greece, Bulgaria). A similar situation was observed for sustainable agriculture measures—the maximum measures (Estonia, Bulgaria, Slovakia, Lithuania) were about two times higher than the minimum measures (Poland, Malta, Slovenia, Luxembourg). The findings indicate that, on the one hand, there have been favourable developments at the national level in Europe, but also that there are a number of existing disparities, together with evidence of potentially significant deviations from the targets set out in the 2030 Agenda.

The aim of the article was to assess the opinions of consumer credit borrowers on the information message provided to them by lenders at the pre-contractual stage. The opinions were presented in the context of the demographic characteristics of the respondents. The research question posed was whether, taking into account demographic characteristics, the assessment of consumer credit borrowers regarding the information message obtained at the pre-contractual stage varied. The research methodology included a questionnaire and Computer-Assisted Telephone Interviewing (CATI). For the information analysis, we employed the following non-parametric tests: the chi-square test of independence, the Mann–Whitney U test and the Kruskal–Wallis H test. No significant differences were observed in all the parameters of the assessment of the information message, which means that the answer to the research question was negative. The findings suggest that even though borrowers may positively assess the compliance with the information obligations by lenders, it does not mean that all credit decisions made were rational and appropriate to their financial situation. Our study focused on the consumer protection and employed non-parametric tests to analyze the consumer credit borrowers’ assessment of the information provided to them by lenders. First published online 07 June 2024

Gender equality is a fundamental human right and one of the core values of the European Union (EU). Great efforts have been made to defend this right and to promote gender equality within the member states and around the world. However, there are still significant differences between men and women, especially in terms of income. The main objective of the paper is to compare income distributions for gender groups across four Central European countries, Poland, Slovakia, Czechia and Hungary, i.e., the members of the Visegrád Group (V4). These countries share similar histories and similar economic development, but there are substantial differences between their approaches to economic reforms, including labour market policy. This, in turn, is reflected in different income distributions and income inequality patterns. There is a debated research issue regarding the methodology of measuring the gender gap – the traditional methods based on comparing means and medians seem unsatisfactory as they do not consider the shape of income distributions. The paper’s novelty lies in the application of the relative distribution concept, which goes beyond the typical focus on average income differences toward a full comparison of the entire distribution of women’s earnings relative to men’s. In the paper, we implement a parametric approach for estimating the relative distribution, which allows us to compare and visualise the “gap” between the gender groups at each distribution quantile. The basis for the calculations was the microdata from the Luxembourg Income Study (LIS). The statistical methods applied in the study were appropriate to describe the gender gap over the entire income range. The results of the empirical analysis helped to reveal similarities and substantial differences between the countries.

Despite significant advancements in the field of oncology, cancers still pose one of the greatest challenges of modern healthcare. Given the cytoskeleton’s pivotal role in regulating mechanisms critical to cancer development, further studies of the cytoskeletal elements could yield new practical applications. Septins represent a group of relatively well-conserved GTP-binding proteins that constitute the fourth component of the cytoskeleton. Septin 9 (SEPT9) has been linked to a diverse spectrum of malignancies and appears to be the most notable septin member in that category. SEPT9 constitutes a biomarker of colorectal cancer (CRC) and has been positively correlated with a high clinical stage in breast cancer, cervical cancer, and head and neck squamous cell carcinoma. SEPT9_i1 represents the most extensively studied isoform of SEPT9, which substantially contributes to carcinogenesis, metastasis, and treatment resistance. Nevertheless, the mechanistic basis of SEPT9_i1 oncogenicity remains to be fully elucidated. In this review, we highlight SEPT9’s and SEPT9_i1’s structures and interactions with Hypoxia Inducible Factor α (HIF-1 α) and C-Jun N-Terminal Kinase (JNK), as well as discuss SEPT9_i1’s contribution to aneuploidy, cell invasiveness, and taxane resistance—key phenomena in the progression of malignancies. Finally, we emphasize forchlorfenuron and other septin inhibitors as potential chemotherapeutics and migrastatics.

Exportin 1 (XPO1) is a crucial molecule of nucleocytoplasmic transport. Among others, it exports molecules important for oncogenesis from the nucleus to the cytoplasm. The expression of XPO1 is increased in numerous malignancies, which contributes to the abnormal localization of tumor suppressor proteins in the cytoplasm and subsequent cell cycle dysregulation. Selective inhibitors of nuclear export (SINEs) are novel anticancer agents that target XPO1, arrest tumor suppressor proteins in the nucleus, and induce apoptosis in cancer cells. Selinexor, a first-in-class SINE, has already been approved for the treatment of relapsed/refractory multiple myeloma and relapsed/refractory diffuse large B cell lymphoma not otherwise specified. It has also been proven effective in relapsed/refractory and previously untreated acute myeloid leukemia patients. In addition, numerous studies have yielded promising results in other malignancies of the hematopoietic system and solid tumors. However, future clinical use of selinexor and other SINEs may be hampered by their significant toxicity.

Sustainable development counteracts climate change and strives for a good quality of life. It is a development based on economic, social and environmental goals which should be evaluated. Environmental taxes have to ensure enterprises’ development follows sustainability principles. The basis of environmental taxes is a physical unit of harmful substance emissions with a proven negative impact on the environment. The article’s main objective is to assess the impact of environmental taxes (Envtax) on the sustainable development of the transportation and storage enterprises (Susd) (NACE Rev. 2: H) from 2008 to 2018. We created integrated indicators of sustainable development and its components, single-equation and multi-equation models (the OLS estimation) and Model Autoregressive Moving Average with eXogenous (ARMAX) to verify the research hypothesis. The research results indicate that energy (Entax t), transport (Trtax) and pollution taxes (Poltax) from current and previous period significantly affect the development of transportation and storage enterprises within sustainability principles (economic: Ed, social: Sd, and environmental: Envd). There is a strong variation in the strength and direction of the impact of environmental taxes on the development of the transportation and storage enterprises following sustainability principles in Bulgaria, Croatia, Romania, and Slovenia from 2008 to 2018. The results indicate that taxes are not effectively used and that implementing reforms in the European Union in this area is the right direction.

Sustainable development is the subject of many economic analyses, but so far no attempt has been made to identify the main mechanism of interdependence between sustainable energy development and sustainable economic development in the second decade of the 21st century. The particular role of energy in achieving the Sustainable Development Goals is due to the fact that the production, supply and use of energy underpin economic growth. The article fills this research gap and spawns both a better understanding of the essence of sustainable development as well as practical conclusions. The aim is to assess sustainable energy development and sustainable economic development in EU member states and to determine the correlation between the two in the EU. Substantive and formal methods were used to select diagnostic variables, including: the parametric method, the standardized sums method, and correlation analysis. The analysis period covers the years 2014–2021. The conducted research demonstrated a significant variation in the level of sustainable energy development and sustainable economic development among EU countries.

Chitin, a ubiquitous biopolymer, holds paramount scientific and economic significance. Historically, it has been primarily isolated from marine crustaceans. However, the surge in demand for chitin and the burgeoning interest in biopolymers have necessitated the exploration of alternative sources. Among these methods, the mulberry silkworm (Bombyx mori) has emerged as a particularly intriguing prospect. To isolate chitin from Bombyx mori, a chemical extraction methodology was employed. This process involved a series of meticulously orchestrated steps, including Folch extraction, demineralization, deproteinization, and decolorization. The resultant chitin was subjected to comprehensive analysis utilizing techniques such as attenuated total reflectance–Fourier transform infrared spectroscopy (ATR-FTIR), 13C nuclear magnetic resonance (NMR) spectroscopy, and wide-angle X-ray scattering (WAXS). The obtained results allow us to conclude that the Bombyx mori represents an attractive alternative source of α-chitin.

The aim of this study was to obtain a series of activated carbon samples by the chemical activation of low-rank coal. The precursor was impregnated with a NaOH solution. Activated carbons were characterized by determining their textural parameters and content of surface oxygen functional groups and by using an elemental analysis. The carbons were tested as potential adsorbents for the removal of liquid pollutants represented by rhodamine B. The effectiveness of rhodamine B removal from water solutions depended on the initial concentration of the dye, the mass of rhodamine B, and the pH and temperature of the reaction. The isotherm examination followed the Langmuir isotherm model. The maximum adsorption capacity of the rhodamine B was 119 mg/g. The kinetic investigation favored the pseudo-second-order model, indicating a chemisorption mechanism. The thermodynamic assessment indicated spontaneous and endothermic adsorption, with decreased randomness at the solid–liquid interface. The experiment revealed that a 0.1 M HCl solution was the most effective regenerative agent.

In this research, we aimed to design an eco-efficient composite based on alkali-activated materials (AAMs) with self-cleaning properties for sustainable construction. Significant emphasis was placed on determining the role of the type of precursor, the amount of sodium silicate, and the addition of titanium dioxide on the rheological and mechanical properties of AAMs. An important aspect of the research was the modification of AAM with titanium dioxide to obtain the self-cleaning properties. Titanium dioxide, thanks to its photocatalytic properties, enables the reduction of organic pollutants and nitrogen oxides in the urban atmosphere and promotes the cleaning of material surfaces. Blast furnace slag (BFS) was used as the source material, which was then substituted in subsequent formulations with metakaolinite at 50% and fly ash and zeolite at 30%. The best-activated AAMs, in which blast furnace slag and its mixture with metakaolinite were used as precursors, achieved compressive strengths of 50 MPa. BFS mixtures with pozzolans were more difficult to polymerize, although their final strengths were still relatively high, in the range of 33–37 MPa. Adding titanium dioxide (T) improved the final strengths and slightly lowered the heat of hydration and spreading of the AAM mortars. The best self-cleaning properties were achieved with composites that comprised a mixture of blast furnace slag, fly ash, and 2% titanium dioxide.

Abstract In the last decades, biological invasions become the main driver of biodiversity loss. The changes can be noticed not only in the above-ground diversity but also in the underground, including seed banks of native vegetation. In this study, we focus on Rudbeckia laciniata, a species introduced to many European and Asian countries, to characterize its soil seed bank as well as to answer the question, how the species influenced soil seed banks of meadow plant communities in two types of habitats (fresh and wet), where traditional mowing was abandoned. Within the habitats, we conducted our study on a three-step scale of invasion, from full invasion, through the transition zone to the control zone, where no invasion of the species has been observed so far. The majority of the R. laciniata seeds were located in the surface layer of soil. We detected, that 47% (in fresh meadow) and 56% (wet meadow) of recorded species occurred only in a soil seed bank, and were absent in aboveground vegetation. Emergence of native plants from the soil seed bank is low due to rapid shading of the soil surface by R. laciniata seedlings. However, a short-term seed bank of the species gives hope that returning to regular mowing brings the desired results in its the elimination from vegetation, in a fairly short time.

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The potential of diamond-like carbon coatings in medicine can be increased by doping them with various elements. Such modifications especially affect the biological properties of the synthetized films. In the following research, phosphorus was introduced into the carbon matrix by means of the chemical vapor deposition technique and using an organic precursor. With the addition of about 1.6 and 4.3 at% of dopant, not only was the surface roughness increased, but significant changes in both the mechanical and biological properties were also observed. The presence of phosphorus reduced the hardness of DLC coatings but still improved this parameter in comparison to the substrate material—AISI316LVM. A biological examination revealed the bacteriostatic potential of doped coatings regardless of their chemical composition. Increasing the amount of phosphorus improved the proliferation of osteoblasts (Saos-2 cell), but the opposite effect was achieved for the endothelial cell line (EA.hy926). Another important aspect is the reduction in platelet activation, especially for low amounts of dopant. [ABSTRACT FROM AUTHOR]

Recent studies have focused on the development of bio-based products from sustainable resources using green extraction approaches, especially nanocellulose, an emerging nanoparticle with impressive properties and multiple applications. Despite the various sources of cellulose nanofibers, the search for alternative resources that replace wood, such as Lygeum spartum, a fast-growing Mediterranean plant, is crucial. It has not been previously investigated as a potential source of nanocellulose. This study investigates the extraction of novel cellulose micro/nanofibers from Lygeum spartum using a two-step method, including both alkali and mechanical treatment as post-treatment with ultrasound, as well as homogenization using water and dilute alkali solution as a solvent. To determine the structural properties of CNFs, a series of characterization techniques was applied. A significant correlation was observed between the Fourier transform infrared (FTIR) spectroscopy and X-ray diffraction (XRD) results. The FTIR results revealed the elimination of amorphous regions and an increase in the energy of the H-bonding modes, while the XRD results showed that the crystal structure of micro/nanofibers was preserved during the process. In addition, they indicated an increase in the crystallinity index obtained with both methods (deconvolution and Segal). Thermal analysis based on thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) confirmed improvement in the thermal properties of the isolated micro/nanofibers. The temperatures of maximum degradation were 335 °C and 347 °C. Morphological analysis using a scanning electron microscope (SEM) and atomic force microscope (AFM) showed the formation of fibers along the axis, with rough and porous surfaces. The findings indicate the potential of Lygeum spartum as a source for producing high-quality micro/nanofibers. A future direction of study is to use the cellulose micro/nanofibers as additives in recycled paper and to evaluate the mechanical properties of the paper sheets, as well as investigate their use in smart paper. [ABSTRACT FROM AUTHOR]

Atherosclerosis affects human health in many ways, leading to disability or premature death due to ischemic heart disease, stroke, or limb ischemia. Poststenotic blood flow disruption may also play an essential role in artery wall impairment linked with hemolysis related to shear stress. The maximum shear stress in the atherosclerotic plaque area is the main parameter determining hemolysis risk. In our work, a 3D internal carotid artery model was built from CT scans performed on patients qualified for percutaneous angioplasty due to its symptomatic stenosis. The obtained stenosis geometries were used to conduct a series of computer simulations to identify critical parameters corresponding to the increase in shear stress in the arteries. Stenosis shape parameters responsible for the increase in shear stress were determined. The effect of changes in the carotid artery size, length, and degree of narrowing on the change in maximum shear stress was demonstrated. Then, a correlation for the quick initial diagnosis of atherosclerotic stenoses regarding the risk of hemolysis was developed. The developed relationship for rapid hemolysis risk assessment uses information from typical non-invasive tests for treated patients. Practical guidelines have been developed regarding which stenosis shape parameters pose a risk of hemolysis, which may be adapted in medical practice.