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In this paper, the Fisher information (FI), relevant to m-generalized order statistics (m-GOSs) and their concomitants of the shape-parameter of the Sarmanov family of bivariate distributions, is investigated. In addition, we study the concomitants of m-GOSs from this family. Furthermore, we look at how those concomitants were distributed collectively. The FI contained in the scale and shape parameters of the exponential and power function distributions, respectively, in concomitants of m-GOSs is obtained. A study of the asymptotic behavior of the concomitants of ordinary order statistics is also provided. Some versatile applications for this study are offered. As a final step, we examined a bivariate real-world data set for illustrative purposes. [ABSTRACT FROM AUTHOR]

The Molodtsov-initiated soft set theory plays an important role as a powerful mathematical tool for handling uncertainty. As an extension of the soft set, the fuzzy soft set can be seen to be more generic and flexible than utilizing the soft set only that fails to represent problem parameters fuzziness. Through this progress, the fuzzy soft set theory cannot deal with decision-making problems involving multi-attribute sets, bipolarity, or some effective considered parameters. Therefore, the goal of this article is to adapt effectiveness and bipolarity concepts with the multi-fuzzy soft set of order n. One can see that this approach generates a novel, extended, effective decision-making environment that is more applicable than any previously introduced one. In addition, types, concepts, and operations of effective bipolar-valued multi-fuzzy soft sets of dimension n are provided, each with an example. Furthermore, properties like absorption, associative, distributive, commutative, and De Morgan's laws of those new sets are investigated. Moreover, a decision-making methodology under effective bipolar-valued multi-fuzzy soft settings is established. This technique facilitates reaching the final decision that this student is qualified to take a certain education level, or this patient is suffering from a certain disease, etc. In addition, a case study represented in a medical diagnosis example is discussed in detail to make the proposed algorithm clearer. Applying matrix techniques in this example as well as using MATLAB®, not only makes it easier and faster in doing calculations, but also gives more accurate, optimal, and effective decisions. Finally, the sensitivity analysis, as well as a comparison with the existing methods, are conducted in detail and are summarized in a chart to show the difference between them and the current one. [ABSTRACT FROM AUTHOR]

Background: Many drugs are prescribed in relieving acute migraine attacks, we aim to compare metoclopramide with other antimigraine drugs. Methods: We searched online databases like PubMed, Cochrane Library, Scopus, and Web of Science till June 2022 for RCTs that compared metoclopramide alone with placebo or active drugs. The main outcomes were the mean change in headache score and complete headache relief. The secondary outcomes were the rescue medications need, side effects, nausea and recurrence rate. We qualitatively reviewed the outcomes. Then, we performed the network meta-analyses (NMAs) when it was possible. which were done by the Frequentist method using the MetaInsight online software. Results: Sixteen studies were included with a total of 1934 patients: 826 received metoclopramide, 302 received placebo, and 806 received other active drugs. Metoclopramide was effective in reducing headache outcomes even for 24 h. The intravenous route was the most chosen route in the included studies and showed significant positive results regarding headache outcomes; however, the best route whether intramuscular, intravenous, or suppository was not compared in the previous studies. Also, both 10 and 20 mg doses of metoclopramide were effective in improving headache outcomes; however, there was no direct comparison between both doses and the 10 mg dose was the most frequently used dosage. In NMA of headache change after 30 min or 1 h, metoclopramide effect came after granisetron, ketorolac, chlorpromazine, and Dexketoprofen trometamol. Only granisetron's effect was significantly higher than metoclopramide's effect which was only significantly higher than placebo and sumatriptan. In headache-free symptoms, only prochlorperazine was non-significantly higher than metoclopramide which was higher than other medications and showed significantly higher effects only with placebo. In rescue medication, metoclopramide's effect was only non-significantly lower than prochlorperazine and chlorpromazine while its effect was higher than other drugs and showed higher significant effects only than placebo and valproate. In the recurrence rate, studies showed no significant difference between metoclopramide and other drugs. Metoclopramide significantly decreased nausea more than the placebo. Regarding side effects, metoclopramide showed a lower incidence of mild side effects than pethidine and chlorpromazine and showed a higher incidence of mild side effects than placebo, dexamethasone, and ketorolac. The reported extrapyramidal symptoms with metoclopramide were dystonia or akathisia. Conclusion: A dose of 10 mg IV Metoclopramide was effective in relieving migraine attacks with minimal side effects. Compared to other active drugs, it only showed a lower significant effect compared with granisetron regarding headache change while it showed significantly higher effects only with placebo in both rescue medication needs and headache-free symptoms and valproate in only rescue medication need. Also, it significantly decreased headache scores more than placebo and sumatriptan. However, more studies are needed to support our results. [ABSTRACT FROM AUTHOR]

In this work, we reveal some distributional traits of concomitants of order statistics (COSs) arising from the extended Farlie–Gumbel–Morgenstern (FGM) bivariate distribution, which was developed and studied in recent work. The joint distribution and product moments of COSs for this family are discussed. Moreover, some useful recurrence relations between single and product moments of concomitants are obtained. In addition, the asymptotic behavior of the concomitant's rank for order statistics (OSs) is studied. The information measures, differential entropy, Kullback–Leibler (KL) distance, Fisher information number (FIN), and cumulative past inaccuracy (CPI) are theoretically and numerically studied. [ABSTRACT FROM AUTHOR]

In this work, we reveal some distributional characteristics of concomitants of generalized order statistics (GOS) with parameters that are pairwise different, arising from iterated Farlie–Gumbel–Morgenstern (IFGM) family of bivariate distributions. Additionally, the joint distribution and product moments of concomitants of GOS for this family are discussed. Moreover, some well-known information measures, i.e., extropy, cumulative residual extropy (CRJ), and negative cumulative extropy (NCJ), are derived. Applications of these results are given for order statistics, record values, and progressive type-II censored order statistics with uniform marginals distributions. Additionally, the issue of estimating the CRJ and NCJ is looked into, utilizing the empirical technique and the concomitant of GOS. Finally, bivariate real-world data sets have been analyzed for illustrative purposes, and the performance of the proposed method is quite satisfactory. [ABSTRACT FROM AUTHOR]

Background: Previous studies documented a narrow scope of knowledge about the negative mental health status during the lockdown following the COVID-19 pandemic, especially in Arab countries. Aim: We aimed to assess the association between negative mental health status and the COVID-19 pandemic and determine the different factors affecting mental health among the general population of seven Arab countries. Methods: This study is a multinational cross-sectional questionnaire-based survey conducted online from June 11, 2020 to June 25, 2020. The depression, anxiety, and stress Scale 21 Items (DASS-21) and the Event scale--Revised Arabic version (IES-R-13) scales were used. Multiple linear regressions were performed to study the association between the scales' total scores with COVID-19 and demographic characteristics. Results: A total of 28,843 participants from seven Arab countries were included. During the COVID-19 pandemic, the prevalence of mental health disorders has significantly increased. A total of 19006 participants (66%) were affected by variable degrees of depression, 13,688 (47%) had anxiety, and 14,374 (50%) had stress ranging from mild to severe. Higher levels were associated with other factors, such as lower age, female gender, chronic disease, unemployed, fear of getting infected, and a history of psychiatric disorders. Conclusion: Our study findings show an increased incidence of mental disorders during the pandemic. This is expected to play a crucial role in guiding a psychological support strategy provided by healthcare systems to the general public during pandemics. [ABSTRACT FROM AUTHOR]

Background: Abdominal binder is a non-pharmacological method of relieving pain after surgical procedures.Objectives: To evaluate the effectiveness of the abdominal binder in relieving pain and distress scores after cesarean delivery (CD).Search Strategy: The following terms were searched: cesarean section, cesarean, caesarean, abdominal deliveries, C-section, abdominal delivery, abdominal binding, binder, and abdominal binder.Selection Criteria: Randomized controlled trials (RCTs) with patients undergoing CD receiving an abdominal binder compared with non-users of the abdominal binder.Data Collection and Analysis: Five electronic databases were searched until November 2019. Records were screened for eligibility. Data were extracted independently and analyzed. The main outcomes were pain and distress scores.Results: The final analysis included six RCTs. Overall effect estimate favored the abdominal binder group over the control group in the following outcomes: VAS pain scores after 24 h (mean difference [MD] -1.76; 95% confidence interval [CI] -3.14 to -0.39; P = 0.01), VAS scores after 48 h (MD -1.21; 95% CI -1.51 to -0.90; P < 0.001), distress score after 24 h (MD -1.87; 95% CI -3.01 to -0.73; P = 0.001), and distress score after 48 h (MD -1.87; 95% CI -3.07 to -0.67; P = 0.002).Conclusion: The abdominal binder could be an effective, simple, non-pharmacological option of relieving pain and distress after CD. [ABSTRACT FROM AUTHOR]

Aims To evaluate the renin gene (RG) expression pattern in newly diagnosed patients with acute myeloid leukemia (AML), aiming to figure out its prognostic value in correlation with clinical characteristics and outcomes of the chemotherapy course. Settings and design This study was clinical trial performed in the National Cancer Institute (NCI), Cairo University. Patients and methods We investigated the expression of the RG in 90 patients with AML using real-time PCR. Levels of RG were correlated with the different patients' characteristics and outcomes of chemotherapy. Statistical analysis used χ2 test and Student t test were used to compare between RG positive and negative groups. SPSS software was used to perform the statistical analysis. Results RG presented in 90 (72%) patients with AML. Both renin positive and negative populations showed no statistically significant difference, regarding all clinical parameters evaluated and the prognostic outcomes. Positive gene patients were associated with nonsignificantly lower percentages of bone marrow and peripheral blood blasts (P=0.534 and 0.074, respectively). In addition, they showed nonsignificant difference regarding the incidence of all types of cytogenetics (P=0.467) and the same results for Flt3 gene expression (P=0.751). Moreover, they showed nonsignificant difference regarding complete response rates, relapse rates, and survival rates (P=0.473, 0.636, and 0.152, respectively). Conclusion RG expression has no significant role in determining the prognosis of patients with AML. This includes different prognostic outcomes, including response to treatment, survival rates, relapses, and disease-free periods. [ABSTRACT FROM AUTHOR]

We aimed to compare the efficacy of vaginal progesterone versus intramuscular progesterone (IMP) for luteal phase support in assisted reproductive techniques (ART). A comprehensive electronic search of four electronic databases (PubMed, Cochrane Library, Scopus, and ISI Web of Science) was performed from inception till August 2019 for randomized controlled trials (RCTs). We included studies performed different ART with the use of vaginal progesterone versus IMP for luteal phase support. Our primary outcome was clinical pregnancy rate. Our secondary outcomes were ongoing pregnancy, miscarriage, live birth rates, and satisfaction in both groups. 15 RCTs met our inclusion criteria with a total of 5656 patients. Our analysis indicated no significant differences between vaginal progesterone and IMP regarding clinical and ongoing pregnancies (RR = 0.90, 95% CI [0.80, 1.00], p =.06), (RR = 0.90, 95% CI [0.76, 1.06], p =.21), respectively. No significant differences were found between both routes of progesterone in miscarriage (p =.98) and live birth (p =.99). Subgroup analysis between fresh and frozen embryo transfer cycles in above outcomes showed no difference between progesterone routes. Vaginal progesterone was significantly associated with more satisfaction compared to IMP (p <.00001). In conclusion, vaginal progesterone can be used an alternative method for luteal phase support instead of IMP in ART. [ABSTRACT FROM AUTHOR]

The Tsallis entropy is an extension of the Shannon entropy and is used extensively in physics. The cumulative residual Tsallis entropy, which is a generalization of the Tsallis entropy, plays an important role in the measurement uncertainty of random variables and has simple relationships with other important information and reliability measures. In this paper, some novel properties of the cumulative residual Tsallis entropy are disclosed. Moreover, this entropy measure is applied to testing the uniformity, where the limit distribution and an approximation of the distribution of the test statistic are derived. In addition, the property of stability is discussed. Furthermore, the percentage points and power against seven alternative distributions of this test statistic are presented. Finally, to compare the power of the suggested test with that of other tests of uniformity, a simulation study is conducted. [ABSTRACT FROM AUTHOR]

In this paper, we study the concomitants of dual generalized order statistics (and consequently generalized order statistics) when the parameters γ 1 , ... , γ n are assumed to be pairwise different from Huang–Kotz Farlie–Gumble–Morgenstern bivariate distribution. Some useful recurrence relations between single and product moments of concomitants are obtained. Moreover, Shannon's entropy and the Fisher information number measures are derived. Finally, these measures are extensively studied for some well-known distributions such as exponential, Pareto and power distributions. The main motivation of the study of the concomitants of generalized order statistics (as an important practical kind to order the bivariate data) under this general framework is to enable researchers in different fields of statistics to use some of the important models contained in these generalized order statistics only under this general framework. These extended models are frequently used in the reliability theory, such as the progressive type-II censored order statistics. [ABSTRACT FROM AUTHOR]

Objective: The adherence to public health recommendations to control COVID-19 spread is influenced by public knowledge, attitudes and practices (KAP). We performed this cross-sectional study to assess the levels and determinants of public KAP towards COVID-19 in a large, multinational sample., Design: Cross-sectional study (survey)., Setting: The questionnaire was distributed to potential respondents via online platforms., Participants: 71 890 individuals from 22 countries., Methods: We formulated a four-section questionnaire in English, followed by validation and translation into seven languages. The questionnaire was distributed (May to June 2020) and each participant received a score for each KAP section., Results: Overall, the participants had fair knowledge (mean score: 19.24±3.59) and attitudes (3.72±2.31) and good practices (12.12±1.83) regarding COVID-19. About 92% reported moderate to high compliance with national lockdown. However, significant gaps were observed: only 68.2% knew that infected individuals may be asymptomatic; 45.4% believed that antibiotics are an effective treatment; and 55.4% stated that a vaccine has been developed (at the time of data collection). 71.9% believed or were uncertain that COVID-19 is a global conspiracy; 36.8% and 51% were afraid of contacting doctors and Chinese people, respectively. Further, 66.4% reported the pandemic had moderate to high negative effects on their mental health. Female gender, higher education and urban residents had significantly (p≤0.001) higher knowledge and practice scores. Further, we observed significant correlations between all KAP scores., Conclusions: Although the public have fair/good knowledge and practices regarding COVID-19, significant gaps should be addressed. Future awareness efforts should target less advantaged groups and future studies should develop new strategies to tackle COVID-19 negative mental health effects., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)