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112 results on '"Adenylosuccinate lyase"'

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1. Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis.

2. Anticipatory banking of samples enables diagnosis of adenylosuccinase deficiency following molecular autopsy in an infant with vacuolating leukoencephalopathy.

3. Marine cage culture leads to higher IMP content and ADSL gene expression in the muscle of Japanese sea bass (Lateolabrax japonicus) compared with freshwater pond culture.

4. Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis

5. Arg40 is critical for stability and activity of Adenylosuccinate lyase; a purine salvage enzyme from Leishmania donovani.

7. Investigating Immunization With Nucleotide Enzymes of Schistosoma mansoni: Nucleoside Diphosphate Kinase and Adenylosuccinate Lyase as New Antigenic Targets Against Schistosomiasis

8. Parasitaemia data and molecular characterization of Haemoproteus catharti from New World vultures (Cathartidae) reveals a novel clade of Haemosporida

9. Investigating Immunization With Nucleotide Enzymes of Schistosoma mansoni : Nucleoside Diphosphate Kinase and Adenylosuccinate Lyase as New Antigenic Targets Against Schistosomiasis.

10. Anticipatory banking of samples enables diagnosis of adenylosuccinase deficiency following molecular autopsy in an infant with vacuolating leukoencephalopathy

11. Silencing of Dicer enhances dacarbazine resistance in melanoma cells by inhibiting ADSL expression.

12. Enhancement of Pyruvate Productivity in Candida glabrata by Deleting the CgADE13 Gene to Improve Acid Tolerance.

13. Parasitaemia data and molecular characterization of Haemoproteus catharti from New World vultures (Cathartidae) reveals a novel clade of Haemosporida.

14. Findings from Pennsylvania State University (Penn State) in Genomics and Genetics Reported (A Caenorhabditis Elegans Model of Adenylosuccinate Lyase Deficiency Reveals Neuromuscular and Reproductive Phenotypes of Distinct Etiology).

15. New Study Findings from Clinical Pathology Unit Illuminate Research in Epilepsy (Electroclinical features and phenotypic differences in Adenylosuccinate lyase deficiency: long term follow-up of seven patients from four families and appraisal of...).

16. Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).

17. Disorders of purine biosynthesis metabolism

19. Targeting de novo purine synthesis pathway via ADSL depletion impairs liver cancer growth by perturbing mitochondrial function

20. Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention

21. Fumaric acid production by Torulopsis glabrata: Engineering the urea cycle and the purine nucleotide cycle.

22. Clinical and molecular characterization of patients with adenylosuccinate lyase deficiency

23. Structural and kinetic studies on adenylosuccinate lyase from Mycobacterium smegmatis and Mycobacterium tuberculosis provide new insights on the catalytic residues of the enzyme.

24. In silico Metabolic Pathway Analysis Identifying Target Against Leishmaniasis – A Kinetic Modeling Approach

25. Toxoplasma gondiiADSL Knockout Provides Excellent Immune Protection against a Variety of Strains

26. Molecular comparison of Neanderthal and Modern Human adenylosuccinate lyase

27. Parasitaemia data and molecular characterization of Haemoproteus catharti from New World vultures (Cathartidae) reveals a novel clade of Haemosporida

28. Inherent properties of adenylosuccinate lyase could explain S-Ado/SAICAr ratio due to homozygous R426H and R303C mutations.

29. Mechanism of growth inhibition of intraerythrocytic stages of Plasmodium falciparum by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)

30. Pediatric neurological syndromes and inborn errors of purine metabolism

31. The structure of phosphate-bound Escherichia coli adenylosuccinate lyase identifies His171 as a catalytic acid.

32. Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum

33. Clinical, biochemical and molecular findings in seven Polish patients with adenylosuccinate lyase deficiency

34. Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens.

35. Effect of Asp69 and Arg310 on the pK of His68, a key catalytic residue of adenylosuccinate lyase.

36. Substrate and Product Complexes of Escherichia coli Adenylosuccinate Lyase Provide New Insights into the Enzymatic Mechanism

37. Important roles of hydroxylic amino acid residues in the function of Bacillus subtilis adenylosuccinate lyase.

38. Expression, purification, and characterization of stable, recombinant human adenylosuccinate lyase

39. Disorders of purine and pyrimidine metabolism

40. Mapping of the bovine genes of thede novoAMP synthesis pathway.

41. The characterization of mutant Bacillus subtilis adenylosuccinate lyases corresponding to severe human adenylosuccinate lyase deficiencies.

42. Adenylosuccinate lyase of Schistosoma mansoni: gene structure, mRNA expression, and analysis of the predicted peptide structure of a potential chemotherapeutic target

43. Phylogenetic analysis of the genus Plasmodium based on the gene encoding adenylosuccinate lyase

44. Identification of estrogen-responsive genes in chick liver.

45. The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation

46. Homology Modelling and Molecular Docking Studies of Selected Substituted Benzo[d]imidazol-1-yl)methyl)benzimidamide Scaffolds on Plasmodium falciparum Adenylosuccinate Lyase Receptor

47. Reduced purine biosynthesis in humans after their divergence from Neandertals

48. Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design

49. A mild form of adenylosuccinate lyase deficiency in absence of typical brain MRI features diagnosed by whole exome sequencing

50. Adenylosuccinate lyase deficiency

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