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9 results on '"Alahmad, Youssef"'

1. Development and Validation of a Novel Analytical Method (Ion Pair HPLC) For Separating and Determining Bisoprolol Fumarate and Carvedilol in Pure and Their Pharmaceutical Forms.

Author

Alhuseen, Duaa, Alahmad, Youssef, and Alahmad, Shoeb

Subjects
BISOPROLOL, ION pairs, CARVEDILOL, RF values (Chromatography), HIGH performance liquid chromatography
Abstract

Copyright of Baghdad Science Journal is the property of Republic of Iraq Ministry of Higher Education & Scientific Research (MOHESR) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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2. Microbiological and Analytical Evaluation of Semi-Solid Formulations of Doxycycline Hyclate under Accelerated Stability Conditions.

Author

Aasi, Ola, Alahmad, Youssef, Beesh, Mustafa, and Swed, Amin

Subjects
ANTIBACTERIAL agents, MICROBIOLOGICAL assay, CHEMICAL decomposition, PSEUDOMONAS aeruginosa, DOXYCYCLINE
Abstract

Copyright of Baghdad Science Journal is the property of Republic of Iraq Ministry of Higher Education & Scientific Research (MOHESR) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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4. Qualitative and Quantitative Determination of Dapagliflozin Propanediol Monohydrate and Its Related Substances and Degradation Products Using LCMS and Preparative Chromatography Methods.

Author

Ismail, Ali, Haroun, Mohammad, and Alahmad, Youssef

Subjects
SODIUM-glucose cotransporter 2 inhibitors, HEXACHLOROCYCLOHEXANES, DAPAGLIFLOZIN, PROPYLENE glycols, CHROMATOGRAPHIC analysis, SODIUM-glucose cotransporters, GENERIC products
Abstract

Copyright of Baghdad Science Journal is the property of Republic of Iraq Ministry of Higher Education & Scientific Research (MOHESR) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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6. Analysis of Intact Glycoprotein Biopharmaceuticals by Capillary Electrophoresis.

Author

Alahmad, Youssef, Tran, Nguyet Thuy, and Taverna, Myriam

Abstract

Many of the biopharmaceuticals currently produced are glycoproteins in which the oligosaccharide chains can impact markedly on bioactivity, antigenicity, pharmacokinetics, solubility, stability, and protease resistance. Glycosylation profile may vary based on the host system employed to produce a recombinant glycoprotein. Downstream and upstream processes employed to produce the finished product may also significantly impact on the composition of the protein in terms of glycosylation. It is therefore mandatory to control glycoproteins by robust methods able to provide sufficient details on minor modifications. Capillary electrophoresis (CE) has proved its usefulness not only for the characterization of glycoprotein pharmaceuticals but also as a quality-control (QC) tool allowing accurate quantitation. CE has been demonstrated to provide rapid, automated, and quantitative results combined to a high resolving power that meets the requirement for a QC method. This chapter focuses on the most recent (as of mid-2009) applications of CE aimed at producing methods to address either QC or characterization issues for intact glycoproteins used as biopharmaceuticals or relevant for clinical or diagnostic purposes. For biopharmaceutical applications, the discussion encompasses process monitoring, stability testing, control of the finished product or the purified glycoprotein, as well as the influence of process conditions and production steps on the bioproduct structure and glycosylation. Also, the implications of the different CE modes (CZE, CIEF, SDS–CGE, and MEKC) are highlighted and discussed. [ABSTRACT FROM AUTHOR]

Published
2011
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9. Shape-controlled ZnO nanocrystals synthesized via auto combustion method and enhancement of the visible light catalytic activity by decoration on graphene.

Author

Darwish, Maher, Mohammadi, Ali, Assi, Navid, Manuchehri, Qazale Sadr, Alahmad, Youssef, and Abuzerr, Samer

Subjects
*NANOCRYSTAL synthesis, *ZINC oxide, *COMBUSTION, *VISIBLE spectra, *CATALYTIC activity, *GRAPHENE
Abstract

Several shapes of ZnO nanocatalysts have been acquired by the alteration of auto combustion method parameters in order to obtain the most efficient catalyst towards 2-nitrophenol degradation under UV-C. Thereafter, the procedure with tuned parameters was employed to decorate ZnO on graphene nanosheets to improve its visible light driven catalytic performance. Characterization results of the as-prepared nanocatalysts revealed that initial pH, fuel to metal ratio, and calcination temperature have influenced different growth and agglomeration directions. However, XRD patterns indicated the monocrystalline hexagonal phase of all tested products. Furthermore, UV–Vis and FTIR spectra exhibited the red-shift of ZnO absorption towards the visible light region upon loading on graphene and confirmed the successful reduction of graphene oxide by the subsequent preparation steps. Indeed, 2-nitrophenol degradation under visible light irradiation has shown a considerable enhancement with all graphene oxide weights utilized. Moreover, the kinetics of the reaction that fitted to the pseudo first-order kinetic and Langmuir-Hinshelwood models elaborated the dominance of pollutant catalytic degradation over its adsorption despite the improved adsorption in the presence of graphene. Finally, the degradation mechanism we suggested involves mainly the surface complexation of 2-NP on the catalyst surface to enable the absorption of visible light through ligand-to-metal charge transfer. [ABSTRACT FROM AUTHOR]

Published
2017
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