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149 results on '"Aref, Hany"'

2. Do stroke services still show sex differences? A multicenter study

Author

Nahas, Nevine El, Shokri, Hossam, Roushdy, Tamer, Dawood, Noha, Zaki, Amr, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Al Hashmi, Amal, Brola, Waldemar, Kosno, Krystian, Falup-Pecurariu, Cristian, Ciopleias, Bogdan, Montaner, Joan, Pérez-Sánchez, Soledad, Mittal, Manoj, Dowd, Kandis, Banke, Annie, Vigilante, Nicholas, Siegler, James, Ozdemir, Atilla Ozcan, Aykac, Ozlem, Kocabas, Zehra Uysal, Melgarejo, Donoband, Cardozo, Analia, Peralta, Lorena, Aref, Hany, and Caso, Valeria

Published
2024
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6. Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials

Author

Klug, Didier, Casolla, Barbara, Puy, Laurent, Coffee, Morgane, Kuchcinski, Grégory, Labreuche, Julien, van Nieuwenhuizen, Koen M., Algra, Ale, van Gelder, Isabelle C., Kappelle, L. Jaap, Rinkel, Gabriel J.E., Schutgens, Roger E.G., Khatri, Pooja, Conwit, Robin, Falcone, Guido, Elm, Jordan, Anderson, Craig S., Song, Lili, Pandian, Jeyaraj, Hart, Robert G., Sharma, Mukul, Aref, Hany, Tarhuni, Wadea, Fabregas, Joan Marti, Diener, Hans-Christoph, Endres, Matthias, Lemmens, Robin, Kwon, Sun U., Lee, Byung-Chul, Ameriso, Sebastian, Milling, Truman J., Kasner, Scott E., Mikulik, Robert, Xavier, Denis, Beer, Ronny, Toni, Danilo, Eckstein, Jens, Seiffge, David, Ferro, Jose M., Tsivgoulis, Georgios, Sharma, Sanjib K., Wei-Liou, Chia, Hohnloser, Stefan H., Katsanos, Aristeidis, Bosch, Jackie, Healey, Jeff, Eikelboom, John, Khaw, Alexander, Gladstone, David, Pikula, Aleksandra, Coutts, Shelagh, Smith, Eric E., Butcher, Ken, Field, Thalia, Gioia, Laura, Stapf, Christian, Halse, Omid, Ringleb, Peter, Enzinger, Christian, Sibon, Igor, Montaner, Joan, Caso, Valeria, Heuschmann, Peter, Lip, Gregory Y.H., Haefeli, Walter, Debette, Stefanie, Dennis, Martin S., Wyller, Torgeir Bruun, Rønning, Ole M., Eilertsen, Helle, Ihle-Hansen, Hege, Sandset, Else Charlotte, Pennlert, Johanna, Glader, Eva-Lotta, Kruuse, Christina, Wester, Per, Carlsson, Maria, Forfang, Elisabeth, Al-Shahi Salman, Rustam, Stephen, Jacqueline, Tierney, Jayne F, Lewis, Steff C, Newby, David E, Parry-Jones, Adrian R, White, Philip M, Connolly, Stuart J, Benavente, Oscar R, Dowlatshahi, Dar, Cordonnier, Charlotte, Viscoli, Catherine M, Sheth, Kevin N, Kamel, Hooman, Veltkamp, Roland, Larsen, Kristin T, Hofmeijer, Jeannette, Kerkhoff, Henk, Schreuder, Floris H B M, Shoamanesh, Ashkan, Klijn, Catharina J M, and van der Worp, H Bart

Published
2023
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9. Did COVID-19 impact stroke services? A multicenter study

Author

Shokri, Hossam, Nahas, Nevine El, Basiony, Ahmed El, Nguyen, Thanh N., Abdalkader, Mohamad, Klein, Piers, Lavados, Pablo M., Olavarría, Verónica V., Amaya, Pablo, Llanos-Leyton, Natalia, Brola, Waldemar, Michał, Lipowski, Fariña, Donoband Edson Dejesus Melgarejo, Cardozo, Analia, Caballero, Cesar David, Pedrozo, Fatima, Rahman, Aminur, Hokmabadi, Elyar Sadeghi, Jalili, Javad, Farhoudi, Mehdi, Aref, Hany, and Roushdy, Tamer

Published
2022
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11. A note of thanks

Author

Abdulghani, M. Ossama, Shehab, Mohammad S., Aref, Hany, Nassef, Ayman, Abdelalim, Ahmed M., Abdulghani, Khaled O., Badry, Reda, Kamel, Mona S., and Elsamman, Amr

Published
2022
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12. The MuSC-19 study: The Egyptian cohort

Author

Zakaria, Magd, Ponzano, Marta, Schiavetti, Irene, Carmisciano, Luca, Nada, Mona, AbdelNaseer, Maged, Zamzam, Dina, Masoud, Janet, Aref, Hany, Shalaby, Nevin, AbdelNaser, Azza, Hamdy, Sherif, Saad, Mahmoud, Shehata, Hatem, Aly, Mohamed, Kishk, Nirmeen, Hamdy, Eman, Hassan, Amr, Hashish, Ahmed, Ahmed, Sandra, Foad, Mohamed, and Sormani, Maria Pia

Published
2021
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14. Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17

Author

Deshpande, Aniruddha, Miller-Petrie, Molly K, Lindstedt, Paulina A, Baumann, Mathew M, Johnson, Kimberly B, Blacker, Brigette F, Abbastabar, Hedayat, Abd-Allah, Foad, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abegaz, Kedir Hussein, Abejie, Ayenew Negesse, Abreu, Lucas Guimarães, Abrigo, Michael R.M., Abualhasan, Ahmed, Accrombessi, Manfred Mario Kokou, Adamu, Abdu A, Adebayo, Oladimeji M, Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adetokunboh, Olatunji O, Adhikari, Tara Ballav, Afarideh, Mohsen, Agudelo-Botero, Marcela, Ahmadi, Mehdi, Ahmadi, Keivan, Ahmed, Muktar Beshir, Ahmed, Anwar E, Akalu, Temesgen Yihunie, Akanda, Ali S, Alahdab, Fares, Al-Aly, Ziyad, Alam, Samiah, Alam, Noore, Alamene, Genet Melak, Alanzi, Turki M, Albright, James, Albujeer, Ammar, Alcalde-Rabanal, Jacqueline Elizabeth, Alebel, Animut, Alemu, Zewdie Aderaw, Ali, Muhammad, Alijanzadeh, Mehran, Alipour, Vahid, Aljunid, Syed Mohamed, Almasi, Ali, Almasi-Hashiani, Amir, Al-Mekhlafi, Hesham M, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J., Amini, Saeed, Amit, Arianna Maever L., Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Anjomshoa, Mina, Ansariadi, Ansariadi, Antonio, Carl Abelardo T., Antony, Benny, Antriyandarti, Ernoiz, Arabloo, Jalal, Aref, Hany Mohamed Amin, Aremu, Olatunde, Armoon, Bahram, Arora, Amit, Aryal, Krishna K, Arzani, Afsaneh, Asadi-Aliabadi, Mehran, Asmelash, Daniel, Atalay, Hagos Tasew, Athari, Seyyede Masoume, Athari, Seyyed Shamsadin, Atre, Sachin R, Ausloos, Marcel, Awasthi, Shally, Awoke, Nefsu, Ayala Quintanilla, Beatriz Paulina, Ayano, Getinet, Ayanore, Martin Amogre, Aynalem, Yared Asmare, Azari, Samad, Azman, Andrew S, Babaee, Ebrahim, Badawi, Alaa, Bagherzadeh, Mojtaba, Bakkannavar, Shankar M, Balakrishnan, Senthilkumar, Banach, Maciej, Banoub, Joseph Adel Mattar, Barac, Aleksandra, Barboza, Miguel A, Bärnighausen, Till Winfried, Basu, Sanjay, Bay, Vo Dinh, Bayati, Mohsen, Bedi, Neeraj, Beheshti, Mahya, Behzadifar, Meysam, Behzadifar, Masoud, Bejarano Ramirez, Diana Fernanda, Bell, Michelle L, Bennett, Derrick A., Benzian, Habib, Berbada, Dessalegn Ajema, Bernstein, Robert S, Bhat, Anusha Ganapati, Bhattacharyya, Krittika, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A, Bijani, Ali, Bikbov, Boris, Bin Sayeed, Muhammad Shahdaat, Biswas, Raaj Kishore, Bohlouli, Somayeh, Boufous, Soufiane, Brady, Oliver J, Briko, Andrey Nikolaevich, Briko, Nikolay Ivanovich, Britton, Gabrielle B, Brown, Alexandria, Burugina Nagaraja, Sharath, Butt, Zahid A, Cámera, Luis Alberto, Campos-Nonato, Ismael R, Campuzano Rincon, Julio Cesar, Cano, Jorge, Car, Josip, Cárdenas, Rosario, Carvalho, Felix, Castañeda-Orjuela, Carlos A, Castro, Franz, Cerin, Ester, Chalise, Binaya, Chattu, Vijay Kumar, Chin, Ken Lee, Christopher, Devasahayam J, Chu, Dinh-Toi, Cormier, Natalie Maria, Costa, Vera Marisa, Cromwell, Elizabeth A, Dadi, Abel Fekadu Fekadu, Dahiru, Tukur, Dahlawi, Saad M A, Dandona, Rakhi, Dandona, Lalit, Dang, Anh Kim, Daoud, Farah, Darwesh, Aso Mohammad, Darwish, Amira Hamed, Daryani, Ahmad, Das, Jai K, Das Gupta, Rajat, Dash, Aditya Prasad, Dávila-Cervantes, Claudio Alberto, Davis Weaver, Nicole, De la Hoz, Fernando Pio, De Neve, Jan-Walter, Demissie, Dereje Bayissa, Demoz, Gebre Teklemariam, Denova-Gutiérrez, Edgar, Deribe, Kebede, Desalew, Assefa, Dharmaratne, Samath Dhamminda, Dhillon, Preeti, Dhimal, Meghnath, Dhungana, Govinda Prasad, Diaz, Daniel, Dipeolu, Isaac Oluwafemi, Do, Hoa Thi, Dolecek, Christiane, Doyle, Kerrie E, Dubljanin, Eleonora, Duraes, Andre Rodrigues, Edinur, Hisham Atan, Effiong, Andem, Eftekhari, Aziz, El Nahas, Nevine, El Sayed Zaki, Maysaa, El Tantawi, Maha, Elhabashy, Hala Rashad, El-Jaafary, Shaimaa I., El-Khatib, Ziad, Elkout, Hajer, Elsharkawy, Aisha, Enany, Shymaa, Endalew, Daniel Adane, Eshrati, Babak, Eskandarieh, Sharareh, Etemadi, Arash, Ezekannagha, Oluchi, Faraon, Emerito Jose A., Fareed, Mohammad, Faro, Andre, Farzadfar, Farshad, Fasil, Alebachew Fasil, Fazlzadeh, Mehdi, Feigin, Valery L., Fekadu, Wubalem, Fentahun, Netsanet, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Filip, Irina, Fischer, Florian, Flohr, Carsten, Foigt, Nataliya A., Folayan, Morenike Oluwatoyin, Foroutan, Masoud, Franklin, Richard Charles, Frostad, Joseph Jon, Fukumoto, Takeshi, Gad, Mohamed M, Garcia, Gregory M, Gatotoh, Augustine Mwangi, Gayesa, Reta Tsegaye, Gebremedhin, Ketema Bizuwork, Geramo, Yilma Chisha Dea, Gesesew, Hailay Abrha, Gezae, Kebede Embaye, Ghashghaee, Ahmad, Ghazi Sherbaf, Farzaneh, Gill, Tiffany K, Gill, Paramjit Singh, Ginindza, Themba G, Girmay, Alem, Gizaw, Zemichael, Goodridge, Amador, Gopalani, Sameer Vali, Goulart, Bárbara Niegia Garcia, Goulart, Alessandra C, Grada, Ayman, Green, Manfred S, Gubari, Mohammed Ibrahim Mohialdeen, Gugnani, Harish Chander, Guido, Davide, Guimarães, Rafael Alves, Guo, Yuming, Gupta, Rajeev, Gupta, Rahul, Ha, Giang Hai, Haagsma, Juanita A., Hafezi-Nejad, Nima, Haile, Dessalegn H, Haile, Michael Tamene, Hall, Brian J., Hamidi, Samer, Handiso, Demelash Woldeyohannes, Haririan, Hamidreza, Hariyani, Ninuk, Hasaballah, Ahmed I., Hasan, Md. Mehedi, Hasanzadeh, Amir, Hassen, Hamid Yimam, Hayelom, Desta Haftu, Hegazy, Mohamed I, Heibati, Behzad, Heidari, Behnam, Hendrie, Delia, Henok, Andualem, Herteliu, Claudiu, Heydarpour, Fatemeh, Hidru, Hagos Degefa de, Hird, Thomas R, Hoang, Chi Linh, Hollerich, Gillian I, Hoogar, Praveen, Hossain, Naznin, Hosseinzadeh, Mehdi, Househ, Mowafa, Hu, Guoqing, Humayun, Ayesha, Hussain, Syed Ather, Hussen, Mamusha Aman A, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Milena D., Imani-Nasab, Mohammad Hasan, Iqbal, Usman, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Ivers, Rebecca Q, Iwu, Chinwe Juliana, Jahanmehr, Nader, Jakovljevic, Mihajlo, Jalali, Amir, Jayatilleke, Achala Upendra, Jenabi, Ensiyeh, Jha, Ravi Prakash, Jha, Vivekanand, Ji, John S, Jonas, Jost B., Jozwiak, Jacek Jerzy, Kabir, Ali, Kabir, Zubair, Kanchan, Tanuj, Karch, André, Karki, Surendra, Kasaeian, Amir, Kasahun, Gebremicheal Gebreslassie, Kasaye, Habtamu Kebebe, Kassa, Gebrehiwot G, Kassa, Getachew Mullu, Kayode, Gbenga A., Kebede, Mihiretu M, Keiyoro, Peter Njenga, Ketema, Daniel Bekele, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khalid, Nauman, Khalilov, Rovshan, Khan, Ejaz Ahmad, Khan, Junaid, Khan, Md Nuruzzaman, Khatab, Khaled, Khater, Mona M, Khater, Amir M, Khayamzadeh, Maryam, Khazaei, Mohammad, Khosravi, Mohammad Hossein, Khubchandani, Jagdish, Kiadaliri, Ali, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Sezer, Kisa, Adnan, Kochhar, Sonali, Kolola, Tufa, Komaki, Hamidreza, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Krishan, Kewal, Kuate Defo, Barthelemy, Kugbey, Nuworza, Kumar, Pushpendra, Kumar, G Anil, Kumar, Manasi, Kusuma, Dian, La Vecchia, Carlo, Lacey, Ben, Lal, Aparna, Lal, Dharmesh Kumar, Lam, Hilton, Lami, Faris Hasan, Lansingh, Van Charles, Lasrado, Savita, Lebedev, Georgy, Lee, Paul H, LeGrand, Kate E, Leili, Mostafa, Lenjebo, Tsegaye Lolaso, Leshargie, Cheru Tesema, Levine, Aubrey J, Lewycka, Sonia, Li, Shanshan, Linn, Shai, Liu, Shiwei, Lopez, Jaifred Christian F, Lopukhov, Platon D, Magdy Abd El Razek, Muhammed, Mahadeshwara Prasad, D.R., Mahasha, Phetole Walter, Mahotra, Narayan B., Majeed, Azeem, Malekzadeh, Reza, Malta, Deborah Carvalho, Mamun, Abdullah A, Manafi, Navid, Mansournia, Mohammad Ali, Mapoma, Chabila Christopher, Martinez, Gabriel, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Mathur, Manu Raj, Mayala, Benjamin K, Mazidi, Mohsen, McAlinden, Colm, Meharie, Birhanu Geta, Mehndiratta, Man Mohan, Mehrabi Nasab, Entezar, Mehta, Kala M, Mekonnen, Teferi, Mekonnen, Tefera Chane, Meles, Gebrekiros Gebremichael, Meles, Hagazi Gebre, Memiah, Peter T N, Memish, Ziad A, Mendoza, Walter, Menezes, Ritesh G, Mereta, Seid Tiku, Meretoja, Tuomo J, Mestrovic, Tomislav, Metekiya, Workua Mekonnen, Miazgowski, Bartosz, Miller, Ted R, Mini, GK, Mirrakhimov, Erkin M, Moazen, Babak, Mohajer, Bahram, Mohammad, Yousef, Mohammad, Dara K., Mohammad Gholi Mezerji, Naser, Mohammadibakhsh, Roghayeh, Mohammed, Shafiu, Mohammed, Jemal Abdu, Mohammed, Hassen, Mohebi, Farnam, Mokdad, Ali H, Moodley, Yoshan, Moradi, Masoud, Moradi, Ghobad, Moradi-Joo, Mohammad, Moraga, Paula, Morales, Linda, Mosapour, Abbas, Mosser, Jonathan F., Mouodi, Simin, Mousavi, Seyyed Meysam, Mozaffor, Miliva, Munro, Sandra B, Muriithi, Moses K., Murray, Christopher J L, Musa, Kamarul Imran, Mustafa, Ghulam, Muthupandian, Saravanan, Naderi, Mehdi, Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Naik, Gurudatta, Nangia, Vinay, Nascimento, Bruno Ramos, Nazari, Javad, Ndwandwe, Duduzile Edith, Negoi, Ionut, Netsere, Henok Biresaw, Ngunjiri, Josephine W., Nguyen, Cuong Tat, Nguyen, Huong Lan Thi, Nguyen, QuynhAnh P, Nigatu, Solomon Gedlu, Ningrum, Dina Nur Anggraini, Nnaji, Chukwudi A, Nojomi, Marzieh, Norheim, Ole F, Noubiap, Jean Jacques, Oancea, Bogdan, Ogbo, Felix Akpojene, Oh, In-Hwan, Olagunju, Andrew T, Olusanya, Jacob Olusegun, Olusanya, Bolajoko Olubukunola, Onwujekwe, Obinna E, Ortega-Altamirano, Doris V., Osarenotor, Osayomwanbo, Osei, Frank B, Owolabi, Mayowa O, P A, Mahesh, Padubidri, Jagadish Rao., Pakhale, Smita, Pana, Adrian, Park, Eun-Kee, Patel, Sangram Kishor, Pathak, Ashish, Patle, Ajay, Paulos, Kebreab, Pepito, Veincent Christian Filipino, Perico, Norberto, Pervaiz, Aslam, Pescarini, Julia Moreira, Pesudovs, Konrad, Pham, Hai Quang, Pigott, David M, Pilgrim, Thomas, Pirsaheb, Meghdad, Poljak, Mario, Pollock, Ian, Postma, Maarten J, Pourmalek, Farshad, Pourshams, Akram, Prada, Sergio I, Preotescu, Liliana, Quintana, Hedley, Rabiee, Navid, Rabiee, Mohammad, Radfar, Amir, Rafiei, Alireza, Rahim, Fakher, Rahimi, Siavash, Rahimi-Movaghar, Vafa, Rahman, Muhammad Aziz, Rahman, Mohammad Hifz Ur, Rajati, Fatemeh, Ranabhat, Chhabi Lal, Rao, Puja C, Rasella, Davide, Rath, Goura Kishor, Rawaf, Salman, Rawal, Lal, Rawasia, Wasiq Faraz, Remuzzi, Giuseppe, Renjith, Vishnu, Renzaho, Andre M.N., Resnikoff, Serge, Riahi, Seyed Mohammad, Ribeiro, Ana Isabel, Rickard, Jennifer, Roever, Leonardo, Ronfani, Luca, Rubagotti, Enrico, Rubino, Salvatore, Saad, Anas M, Sabour, Siamak, Sadeghi, Ehsan, Saeedi Moghaddam, Sahar, Safari, Yahya, Sagar, Rajesh, Sahraian, Mohammad Ali, Sajadi, S. Mohammad, Salahshoor, Mohammad Reza, Salam, Nasir, Saleem, Ahsan, Salem, Hosni, Salem, Marwa Rashad, Salimi, Yahya, Salimzadeh, Hamideh, Samy, Abdallah M, Sanabria, Juan, Santos, Itamar S, Santric-Milicevic, Milena M., Sao Jose, Bruno Piassi, Saraswathy, Sivan Yegnanarayana Iyer, Sarrafzadegan, Nizal, Sartorius, Benn, Sathian, Brijesh, Sathish, Thirunavukkarasu, Satpathy, Maheswar, Sawhney, Monika, Sayyah, Mehdi, Sbarra, Alyssa N, Schaeffer, Lauren E, Schwebel, David C, Senbeta, Anbissa Muleta, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Serván-Mori, Edson, Shafieesabet, Azadeh, Shaheen, Amira A, Shahid, Izza, Shaikh, Masood Ali, Shalash, Ali S, Shams-Beyranvand, Mehran, Shamsi, MohammadBagher, Shamsizadeh, Morteza, Shannawaz, Mohammed, Sharafi, Kiomars, Sharma, Rajesh, Sheikh, Aziz, Shetty, B Suresh Kumar, Shiferaw, Wondimeneh Shibabaw, Shigematsu, Mika, Shin, Jae Il, Shiri, Rahman, Shirkoohi, Reza, Shivakumar, K M, Si, Si, Siabani, Soraya, Siddiqi, Tariq Jamal, Silva, Diego Augusto Santos, Singh, Virendra, Singh, Narinder Pal, Singh, Balbir Bagicha Singh, Singh, Jasvinder A., Singh, Ambrish, Sinha, Dhirendra Narain, Sisay, Malede Mequanent, Skiadaresi, Eirini, Smith, David L, Soares Filho, Adauto Martins, Sobhiyeh, Mohammad Reza, Sokhan, Anton, Soriano, Joan B, Sorrie, Muluken Bekele, Soyiri, Ireneous N, Spurlock, Emma Elizabeth, Sreeramareddy, Chandrashekhar T, Sudaryanto, Agus, Sufiyan, Mu'awiyyah Babale, Suleria, Hafiz Ansar Rasul, Sykes, Bryan L., Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tadesse, Degena Bahrey, Tarigan, Ingan Ukur, Taye, Bineyam, Tefera, Yonatal Mesfin, Tehrani-Banihashemi, Arash, Tekelemedhin, Shishay Wahdey, Tekle, Merhawi Gebremedhin, Temsah, Mohamad-Hani, Tesfay, Berhe Etsay, Tesfay, Fisaha Haile, Tessema, Zemenu Tadesse, Thankappan, Kavumpurathu Raman, ThekkePurakkal, Akhil Soman, Thomas, Nihal, Thompson, Robert L, Thomson, Alan J, Topor-Madry, Roman, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Bach Xuan, Tran, Khanh Bao, Ullah, Irfan, Unnikrishnan, Bhaskaran, Usman, Muhammad Shariq, Uthman, Olalekan A, Uzochukwu, Benjamin S. Chudi, Valdez, Pascual R, Varughese, Santosh, Veisani, Yousef, Violante, Francesco S, Vollmer, Sebastian, W/hawariat, Feleke Gebremeskel, Waheed, Yasir, Wallin, Mitchell Taylor, Wang, Yuan-Pang, Wang, Yafeng, Wangdi, Kinley, Weiss, Daniel J, Weldesamuel, Girmay Teklay, Werkneh, Adhena Ayaliew, Westerman, Ronny, Wiangkham, Taweewat, Wiens, Kirsten E, Wijeratne, Tissa, Wiysonge, Charles Shey, Wolde, Haileab Fekadu, Wondafrash, Dawit Zewdu, Wonde, Tewodros Eshete, Worku, Getasew Taddesse, Yadollahpour, Ali, Yahyazadeh Jabbari, Seyed Hossein, Yamada, Tomohide, Yaseri, Mehdi, Yatsuya, Hiroshi, Yeshaneh, Alex, Yilma, Mekdes Tigistu, Yip, Paul, Yisma, Engida, Yonemoto, Naohiro, Younis, Mustafa Z, Yousof, Hebat-Allah Salah A, Yu, Chuanhua, Yusefzadeh, Hasan, Zadey, Siddhesh, Zahirian Moghadam, Telma, Zaidi, Zoubida, Zaman, Sojib Bin, Zamani, Mohammad, Zandian, Hamed, Zar, Heather J, Zerfu, Taddese Alemu, Zhang, Yunquan, Ziapour, Arash, Zodpey, Sanjay, Zuniga, Yves Miel H, Hay, Simon I, and Reiner, Robert C, Jr

Published
2020
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15. Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17

Author

Wiens, Kirsten E, Lindstedt, Paulina A, Blacker, Brigette F, Johnson, Kimberly B, Baumann, Mathew M, Schaeffer, Lauren E, Abbastabar, Hedayat, Sr, Abd-Allah, Foad, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abegaz, Kedir Hussein, Abejie, Ayenew Negesse, Abreu, Lucas Guimarães, Abrigo, Michael R M, Abualhasan, Ahmed, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Adabi, Maryam, Adamu, Abdu A, Adebayo, Oladimeji M, Adedoyin, Rufus Adesoji, Sr, Adekanmbi, Victor, Adetokunboh, Olatunji O, Sr, Adhena, Beyene Meressa, Afarideh, Mohsen, Ahmad, Sohail, Ahmadi, Keivan, Ahmed, Anwar E, Ahmed, Muktar Beshir, Ahmed, Rushdia, Akalu, Temesgen Yihunie, Alahdab, Fares, Al-Aly, Ziyad, Alam, Noore, Sr, Alam, Samiah, Alamene, Genet Melak, Alanzi, Turki M, Alcalde-Rabanal, Jacqueline Elizabeth, Ali, Beriwan Abdulqadir, Alijanzadeh, Mehran, Alipour, Vahid, Aljunid, Syed Mohamed, Almasi, Ali, Sr, Almasi-Hashiani, Amir, Al-Mekhlafi, Hesham M, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Amini, Saeed, Sr, Amit, Arianna Maever L, Sr, Andrei, Catalina Liliana, Sr, Anjomshoa, Mina, Anoushiravani, Amir, Sr, Ansari, Fereshteh, Antonio, Carl Abelardo T, Antony, Benny, Antriyandarti, Ernoiz, Arabloo, Jalal, Aref, Hany Mohamed Amin, Sr, Aremu, Olatunde, Armoon, Bahram, Arora, Amit, Sr, Aryal, Krishna K, Arzani, Afsaneh, Asadi-Aliabadi, Mehran, Atalay, Hagos Tasew, Athari, Seyyed Shamsadin, Sr, Athari, Seyyede Masoume, Atre, Sachin R, Ausloos, Marcel, Awoke, Nefsu, Ayala Quintanilla, Beatriz Paulina, Ayano, Getinet, Ayanore, Martin Amogre, Sr, Aynalem IV, Yared Asmare, Azari, Samad, Azzopardi, Peter S, Babaee, Ebrahim, Babalola, Tesleem Kayode, Badawi, Alaa, Sr, Bairwa, Mohan, Bakkannavar, Shankar M, Balakrishnan, Senthilkumar, Bali, Ayele Geleto, Banach, Maciej, Sr, Banoub, Joseph Adel Mattar, Sr, Barac, Aleksandra, Bärnighausen, Till Winfried, Basaleem, Huda, Basu, Sanjay, Bay, Vo Dinh, Bayati, Mohsen, Baye, Estifanos, Bedi, Neeraj, Beheshti, Mahya Mahya Beheshti, 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Mohammed Shariful, Iwu, Chinwe Juliana, Izadi, Neda, Sr, Jaca, Anelisa, Jahanmehr, Nader, Jakovljevic, Mihajlo, Jalali, Amir, Jayatilleke, Achala Upendra, Jha, Ravi Prakash, Jha, Vivekanand, Ji, John S, Sr, Jonas, Jost B, Jozwiak, Jacek Jerzy, Kabir, Ali, Kabir, Zubair, Sr, Kahsay, Amaha, Kalani, Hamed, Kanchan, Tanuj, Karami Matin, Behzad, Karch, André, Karim, Mohd Anisul, Karimi-Sari, Hamidreza, Karki, Surendra, Kasaeian, Amir, Kasahun, Gebremicheal Gebreslassie, Kasahun, Yawukal chane, Kasaye, Habtamu Kebebe, Kassa, Gebrehiwot G, Kassa, Getachew Mullu, Kayode, Gbenga A, Kazemi Karyani, Ali, Kebede, Mihiretu M, Keiyoro, Peter Njenga, Kelbore, Abraham Getachew, Sr, Kengne, Andre Pascal, Sr, Ketema, Daniel Bekele, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khalid, Nauman, Khalilov, Rovshan, Khan, Ejaz Ahmad, Sr, Khan, Junaid, Khan I, Md Nuruzzaman, Khan, Muhammad Shahzeb, Khatab, Khaled, Sr, Khater, Amir M, Khater, Mona M, Khayamzadeh, Maryam, Khazaei, Mohammad, Khazaei, Salman, Khosravi, Mohammad Hossein, Khubchandani, Jagdish, Kiadaliri, Ali, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Kissoon, Niranjan, Sr, KMShivakumar, Shivakumar KM Marulasiddaiah M, Sr, Kochhar, Sonali, Kolola, Tufa, Sr, Komaki, Hamidreza, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Kraemer, Moritz U G, Krishan, Kewal, Kugbey, Nuworza, Kumar, G Anil, Kumar, Manasi, Sr, Kumar, Pushpendra, Kumar, Vivek, Kusuma, Dian, La Vecchia, Carlo, Lacey, Ben, Lad, Sheetal D, Lal, Dharmesh Kumar, Lam, Felix, Lami, Faris Hasan, Sr, Lamichhane, Prabhat, Lansingh, Van Charles, Lasrado, Savita, Laxmaiah, Avula, Lee, Paul H, Sr, LeGrand, Kate E, Leili, Mostafa, Lenjebo, Tsegaye Lolaso, Leshargie, Cheru Tesema, Sr, Levine, Aubrey J, Li, Shanshan, Sr, Linn, Shai, Liu, Shiwei, Liu, Simin, Lodha, Rakesh, Longbottom, Joshua, Lopez, Jaifred Christian F, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Mahadeshwara Prasad, D R, Mahasha, Phetole Walter, Sr, Mahotra, Narayan B, Majeed, Azeem, Malekzadeh, Reza, Sr, Malta, Deborah Carvalho, Mamun, Abdullah A, Sr, Manafi, Navid, Sr, Manda, Ana Laura, Manohar, Narendar Dawani Dawanu, Mansournia, Mohammad Ali, Mapoma, Chabila Christopher, Maravilla, Joemer C, Martinez, Gabriel, Sr, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Masaka, Anthony, Massenburg, Benjamin Ballard, Mathur, Manu Raj, Mayala, Benjamin K, Mazidi, Mohsen, McAlinden, Colm, Meharie, Birhanu Geta, Mehndiratta, Man Mohan, Sr, Mehta, Kala M, Mekonnen, Tefera C Chane, Meles, Gebrekiros Gebremichael, Memiah, Peter T N, Memish, Ziad A, Sr, Mendoza, Walter, Menezes, Ritesh G, Mereta, Seid Tiku, Meretoja, Tuomo J, Sr, Mestrovic, Tomislav, Miazgowski, Bartosz, Mihretie, Kebadnew Mulatu, Sr, Miller, Ted R, Mini, GK, Mirrakhimov, Erkin M, Moazen, Babak, Mohajer, Bahram, Mohamadi-Bolbanabad, Amjad, Mohammad, Dara K, Mohammad, Karzan Abdulmuhsin, Mohammad, Yousef, Mohammad Gholi Mezerji, Naser, Mohammadibakhsh, Roghayeh, Mohammadifard, Noushin, Mohammed, Jemal Abdu, Sr, Mohammed, Shafiu, Mohebi, Farnam, Mokdad, Ali H, Molokhia, Mariam, Monasta, Lorenzo, Moodley, Yoshan, Sr, Moore, Catrin E, Sr, Moradi, Ghobad, Moradi, Masoud, Moradi-Joo, Mohammad, Moradi-Lakeh, Maziar, Moraga, Paula, Morales, Linda, Moreno Velásquez, Ilais, Mosapour, Abbas, Mouodi, Simin, Mousavi, Seyyed Meysam, Mozaffor I, Miliva, Muchie, Kindie Fentahun, Sr, Mulaw, Getahun Fentaw, Sr, Munro, Sandra B, Muriithi, Moses K, Murray, Christopher J L, Murthy, GVS, Musa, Kamarul Imran, Mustafa, Ghulam, Sr, Muthupandian, Saravanan, Sr, Nabhan, Ashraf F, Naderi, Mehdi, Nagarajan, Ahamarshan Jayaraman, Naidoo, Kovin S, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Sr, Nansseu, Jobert Richie, Nascimento, Bruno Ramos, Sr, Nazari, Javad, Ndwandwe, Duduzile Edith, Sr, Negoi, Ionut, Sr, Netsere, Henok Biresaw Netsere, Sr, Ngunjiri, Josephine W, Sr, Nguyen, Cuong Tat, Nguyen, Huong Lan Thi, Nguyen, Trang Huyen, Nigatu, Dabere, Nigatu, Solomon Gedlu, Ningrum, Dina Nur Anggraini, Nnaji, Chukwudi A, Nojomi, Marzieh, Nong, Vuong Minh, Norheim, Ole F, Sr, Noubiap, Jean Jacques, Nouraei Motlagh, Soraya, Oancea, Bogdan, Ogah, Okechukwu Samuel, Ogbo, Felix Akpojene, Oh, In-Hwan, Olagunju, Andrew T, Olagunju, Tinuke O, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Onwujekwe, Obinna E, Sr, Oren, Eyal, Ortega-Altamirano, Doris V V, Sr, Osarenotor, Osayomwanbo, Osei, Frank B, Sr, Owolabi, Mayowa O, P A, Mahesh, Sr, Padubidri, Jagadish Rao, Pakhale, Smita, Patel, Sangram Kishor, Paternina-Caicedo, Angel J, Sr, Pathak, Ashish, Sr, Patton, George C, Paudel, Deepak, Sr, Paulos, Kebreab, Sr, Pepito, Veincent Christian Filipino, Pereira, Alexandre, Perico, Norberto, Pervaiz, Aslam, Pescarini, Julia Moreira, Piroozi, Bakhtiar, Pirsaheb, Meghdad, Postma, Maarten J, Pourjafar, Hadi, Pourmalek, Farshad, Sr, Pourshams, Akram, Poustchi, Hossein, Prada, Sergio I, Sr, Prasad, Narayan, Preotescu, Liliana, Quintana, Hedley, Rabiee, Navid, Radfar, Amir, Rafiei, Alireza, Rahim, Fakher, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rahman, SHAFIUR, Rajati, Fatemeh, Sr, Rana, Saleem Muhammad, Sr, Ranabhat, Chhabi Lal, Rasella, Davide, Rawaf, David Laith, Rawaf, Salman, Sr, Rawal, Lal, Rawasia, Wasiq Faraz, Renjith, Vishnu, Renzaho, Andre M N, Sr, Resnikoff, Serge, Sr, Reta, Melese Abate, Rezaei, Negar, Rezai, Mohammad sadegh, Riahi, Seyed Mohammad, Ribeiro, Ana Isabel, Rickard, Jennifer, Sr, Rios-Blancas, Maria, Roever, Leonardo, Ronfani, Luca, Roro, Elias Merdassa, Sr, Ross, Jennifer M, Rubagotti, Enrico, Rubino, Salvatore, Saad, Anas M, Sabde, Yogesh Damodar, Sabour, Siamak, Sadeghi, Ehsan, Sr, Safari, Yahya, Safari-Faramani, Roya, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, S Mohammad, Salahshoor, Mohammad Reza, Salam, Nasir, Sr, Salamati, Payman, Salem, Hosni, Salem I, Marwa R Rashad, Salimi, Yahya, Salimzadeh, Hamideh, Samy, Abdallah M, Sanabria, Juan, Sr, Santric-Milicevic, Milena M, Sao Jose, Bruno Piassi, Saraswathy, Sivan Yegnanarayana Iyer, Sarkar, Kaushik, Sr, Sarker, Abdur Razzaque, Sarrafzadegan I, Nizal, Sartorius, Benn, Sathian, Brijesh, Sathish, Thirunavukkarasu, Sawhney, Monika, Saxena, Sonia, Sr, Schwebel, David C, Sr, Senbeta IV, Anbissa Muleta, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Serván-Mori, Edson, Sr, Shabaninejad, Hosein, Shafieesabet, Azadeh, Sr, Shaikh, Masood Ali, Shalash, Ali S, Sr, Shallo, Seifadin Ahmed, Shams-Beyranvand, Mehran, Shamsi, MohammadBagher, Shamsizadeh, Morteza, Shannawaz, Mohammed, Sharafi, Kiomars, Sharifi, Hamid, Shehata, Hatem Samir, Sr, Sheikh, Aziz, Shetty, B Suresh Kumar, Sr, Shibuya, Kenji, Sr, Shiferaw, Wondimeneh Shibabaw, Sr, Shifti, Desalegn Markos, Shigematsu, Mika, Shin, Jae Il, Shiri, Rahman, Sr, Shirkoohi, Reza, Siabani, Soraya, Siddiqi, Tariq Jamal, Silva, Diego Augusto Santos, Singh, Ambrish, Singh, Jasvinder A, Singh, Narinder Pal, Singh, Virendra, Sisay, Malede Mequanent, Skiadaresi, Eirini, Sobhiyeh, Mohammad Reza, Sr, Sokhan, Anton, Soltani, Shahin, Somayaji, Ranjani, Soofi, Moslem, Sorrie, Muluken Bekele, Sr, Soyiri, Ireneous N, Sreeramareddy, Chandrashekhar T, Sudaryanto, Agus, Sufiyan, Mu'awiyyah Babale, Sr, Suleria, Hafiz Ansar Rasul, Sultana, Marufa, Sunguya, Bruno Fokas, Sykes, Bryan L, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tadesse, Degena Bahrey, Jr, Tarigan, Ingan Ukur, Tasew, Aberash Abay, Tefera, Yonatal Mesfin, Sr, Tekle, Merhawi Gebremedhin, Temsah, Mohamad-Hani, Tesfay I, Berhe Etsay, Tesfay, Fisaha Haile Haile, Tessema, Belay, Tessema, Zemenu Tadesse, Thankappan, Kavumpurathu Raman, Thomas, Nihal, Toma, Alemayehu Toma, Sr, Topor-Madry, Roman, Tovani-Palone, Marcos Roberto Roberto, Traini, Eugenio, Tran, Bach Xuan, Tran, Khanh Bao, Ullah, Irfan, Unnikrishnan, Bhaskaran, Usman, Muhammad Shariq, Sr, Uzochukwu, Benjamin S Chudi, Sr, Valdez, Pascual R, Varughese, Santosh, Sr, Violante, Francesco S, Sr, Vollmer, Sebastian, Sr, W/hawariat, Feleke Gebremeskel, Sr, Waheed, Yasir, Wallin, Mitchell Taylor, Wang, Yafeng, Wang, Yuan-Pang, Weaver, Marcia, Weji, Bedilu Girma, Weldesamuel, Girmay Teklay, Welgan, Catherine A, Werdecker, Andrea, Westerman, Ronny, Sr, Wiangkham, Taweewat, Wiysonge, Charles Shey, Sr, Wolde, Haileab Fekadu, Sr, Wondafrash, Dawit Zewdu, Wonde, Tewodros Eshete, Sr, Worku, Getasew Taddesse, Sr, Wu, Ai-Min, Xu, Gelin, Yadollahpour, Ali, Yahyazadeh Jabbari, Seyed Hossein, Yamada, Tomohide, Sr, Yatsuya, Hiroshi, Yeshaneh, Alex, Yilgwan, Christopher Sabo, Yilma, Mekdes Tigistu, Yip, Paul, Sr, Yisma, Engida, Yonemoto, Naohiro, Sr, Yoon, Seok-Jun, Younis, Mustafa Z, Yousefifard, Mahmoud, Yousof, Hebat-Allah Salah A, Yu, Chuanhua, Yusefzadeh, Hasan, Zadey, Siddhesh, Zaidi, Zoubida, Zaman, Sojib Bin, Zamani, Mohammad, Zandian, Hamed, Zepro, Nejimu Biza, Zerfu, Taddese Alemu, Zhang, Yunquan, Zhao, Xiu-Ju George, Ziapour, Arash, Zodpey, Sanjay, Sr, Zuniga, Yves Miel H, Hay, Simon I, and Reiner, Robert C, Jr

Published
2020
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27. Borderzone Infarction and Small Vessel Disease in a Sample of Egyptian Stroke Patients: Differences and Similarities

Author

Nahas, Nevine El, Aref, Hany, Alloush, Taha, Fahmy, Nagia, Ahmed, Khaled, Basiouny, Ahmed El, Tork, Mohamed, Elbokl, Ahmed, and Shokri, Hossam

Subjects
Stroke (Disease) -- Statistics -- Complications and side effects, Brain -- Infarction, Health
Abstract

Byline: Nevine. El Nahas, Hany. Aref, Taha. Alloush, Nagia. Fahmy, Khaled. Ahmed, Ahmed. El Basiouny, Mohamed. Tork, Ahmed. Elbokl, Hossam. Shokri Background: The anatomical location of white matter hyperintense lesions [...]

Published
2021

30. The budget impact of alteplase in the treatment of acute ischemic stroke in Egypt.

Author

Aref, Hany, El Nahas, Nevine, Elsisi, Gihan Hamdy, Shokri, Hossam, and Roushdy, Tamer

Subjects
ISCHEMIC stroke, BUDGET, STROKE units, ALTEPLASE, STROKE, CEREBRAL hemorrhage
Abstract

Introduction: Stroke is the second leading cause of mortality worldwide. Five percent of all the disability-adjusted life years (DALYs) lost around the world are attributed to stroke. This study aimed to assess the economic burden of acute ischemic stroke (AIS) in Egypt and reveal the benefits of alteplase treatment by measuring the resource use and costs associated with this treatment compared to the standard of care and extrapolate the overall budget impact of alteplase to the local Egyptian setting over a 5-year time horizon from a societal perspective. Methods: A budget impactmodel was developed to estimate the impact of adding alteplase to the current treatment of AIS patients within the Egyptian healthcare setting. The efficacy data for both arms of the model were sourced from a systematic review of the literature. Resource use and cost data were sourced from a retrospective study. Proportions of patients potentially eligible for treatment and the treatment time distributions were estimated from an analysis of the results of this retrospective data collection. A univariate sensitivity analysis was conducted to assess the robustness of the model results. The input parameters varied between plausible extremes based on a review of available evidence. Results: The total annual costs with alteplase treatment [i.e., drug, symptomatic intracerebral hemorrhage (ICH) management, acute hospitalization, and post- hospitalization costs] for the targeted patients from a societal perspective were estimated to be less than the total annual costs without alteplase. This resulted in savings of approximately EGP 37.2 million ($ 1.2 million), EGP 14.2 million ($ 458.06), EGP -33.0 million ($ -1.06 million), EGP -54.0 million ($ -1.74 million), and EGP -89.8 million ($ -2.89 million) for each of the 5 years, respectively. In year 1, more than 2,787 patients (+30.1%) achieved an excellent outcome and <1,204 patients (-22.3%) had a poor outcome when treated with alteplase. The savings in acute hospitalization and post-hospitalization costs o [ABSTRACT FROM AUTHOR]

Published
2023
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32. Stroke services in MENA: What is there and what is needed.

Author

Aref, Hany, El Nahas, Nevine, Alrukn, Suhail Abdulla, Khan, Maria, Kesraoui, Selma, Alnidawi, Firas, Hokmabadi, Elyar Sadeghi, Farhoudi, Mehdi, Fairooz, Muataz, Batayha, Waleed, Salmeen, Athari, Abdulrahman, Husen, Belahsen, Mohammed Faouzi, Al Hashmi, Amal M., Akhtar, Naveed, Al-Johani, Mohammed, Seidi, Osheik Abu'Asha, Jouhar, Anas, Mhiri, Chokri, and Elbassiouny, Ahmed

Subjects
*STROKE, *STROKE units, *MIDDLE class, *NON-communicable diseases, *SECONDARY prevention, *TRANSCRANIAL direct current stimulation
Abstract

Objectives: Stroke represents a health care challenge to most parts of the world including the Middle East and North Africa (MENA) region. The MENA represents 6% of the world population with an age-standardized stroke rate of 87.7 (78.2–97.6) per 100,000 population. This number is subject to increase given that the cause of morbidity has recently shifted from infectious diseases to non-communicable diseases. Thus, in the coming years, treatment of stroke will pose a major burden on MENA countries which mostly lie in the low to middle income economies. Accordingly, we need to study the state of MENA stroke services in order to recognize and further inform policy makers about any gaps that need to be bridged in this domain. Methods and results: Stroke specialists representing 16 countries filled an online survey that included: screening for risk factors, acute management, diagnostics, medications, post-discharge services, and stroke registries. Results showed that 11 countries screen for risk factors, 16 have neuroimaging studies, 15 provide intravenous thrombolysis (IVT), 13 mechanical thrombectomy (MT) while medications for secondary prevention are available in all countries. However, stroke units are not equally available and even absent in 4 countries, and despite the availability of IVT yet, the rate of administration is still low in 6 countries (<5%), and ranges from 5–20% in 7 countries. Stroke registries and training still need to be implemented in most countries. Conclusion: Although imaging, revascularization therapies and medications for secondary prevention are available in most MENA countries, yet the rate of revascularization is low, so is the number of stroke units insufficient in some countries. Additionally, registries and structured training are still defective. Further field studies are required for more accurate determination of the status of stroke services in the MENA region. [ABSTRACT FROM AUTHOR]

Published
2023
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33. SARS-CoV-2 and Stroke Characteristics

Author

Shahjouei, Shima, Tsivgoulis, Georgios, Farahmand, Ghasem, Koza, Eric, Mowla, Ashkan, Vafaei Sadr, Alireza, Kia, Arash, Vaghefi Far, Alaleh, Mondello, Stefania, Cernigliaro, Achille, Ranta, Annemarei, Punter, Martin, Khodadadi, Faezeh, Naderi, Soheil, Sabra, Mirna, Ramezani, Mahtab, Amini Harandi, Ali, Olulana, Oluwaseyi, Chaudhary, Durgesh, Lyoubi, Aicha, Campbell, Bruce C.V., Arenillas, Juan F., Bock, Daniel, Montaner, Joan, Aghayari Sheikh Neshin, Saeideh, Aguiar de Sousa, Diana, Tenser, Matthew S., Aires, Ana, Alfonso, Mercedes de Lera, Alizada, Orkhan, Azevedo, Elsa, Goyal, Nitin, Babaeepour, Zabihollah, Banihashemi, Gelareh, Bonati, Leo H., Cereda, Carlo W., Chang, Jason J., Crnjakovic, Miljenko, De Marchis, Gian Marco, Del Sette, Massimo, Ebrahimzadeh, Seyed Amir, Farhoudi, Mehdi, Gandoglia, Ilaria, Gonçalves, Bruno, Griessenauer, Christoph J., Murat Hanci, Mehmet, Katsanos, Aristeidis H., Krogias, Christos, Leker, Ronen R., Lotman, Lev, Mai, Jeffrey, Male, Shailesh, Malhotra, Konark, Malojcic, Branko, Mesquita, Teresa, Mir Ghasemi, Asadollah, Mohamed Aref, Hany, Mohseni Afshar, Zeinab, Moon, Jusun, Niemelä, Mika, Rezai Jahromi, Behnam, Nolan, Lawrence, Pandhi, Abhi, Park, Jong-Ho, Marto, João Pedro, Purroy, Francisco, Ranji-Burachaloo, Sakineh, Carreira, Nuno Reis, Requena, Manuel, Rubiera, Marta, Sajedi, Seyed Aidin, Sargento-Freitas, João, Sharma, Vijay K., Steiner, Thorsten, Tempro, Kristi, Turc, Guillaume, Ahmadzadeh, Yasaman, Almasi-Dooghaee, Mostafa, Assarzadegan, Farhad, Babazadeh, Arefeh, Baharvahdat, Humain, Cardoso, Fabricio Buchadid, Dev, Apoorva, Ghorbani, Mohammad, Hamidi, Ava, Hasheminejad, Zeynab Sadat, Hojjat-Anasri Komachali, Sahar, Khorvash, Fariborz, Kobeissy, Firas, Mirkarimi, Hamidreza, Mohammadi-Vosough, Elahe, Misra, Debdipto, Noorian, Ali Reza, Nowrouzi-Sohrabi, Peyman, Paybast, Sepideh, Poorsaadat, Leila, Roozbeh, Mehrdad, Sabayan, Behnam, Salehizadeh, Saeideh, Saberi, Alia, Sepehrnia, Mercedeh, Vahabizad, Fahimeh, Yasuda, Thomas Alexandre, Ghabaee, Mojdeh, Rahimian, Nasrin, Harirchian, Mohammad Hossein, Borhani-Haghighi, Afshin, Azarpazhooh, Mahmoud Reza, Arora, Rohan, Ansari, Saeed, Avula, Venkatesh, Li, Jiang, Abedi, Vida, and Zand, Ramin

Subjects
Adult, Male, Risk, Original Contributions, International Cooperation, intracranial hemorrhages, Clinical and Population Sciences, Sinus Thrombosis, Intracranial, Young Adult, Humans, Prospective Studies, Aged, Ischemic Stroke, Venous Thrombosis, neuroimaging, Geography, COVID-19, cerebrovascular disorders, Middle Aged, stroke, Treatment Outcome, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Female, Health Expenditures
Abstract

Supplemental Digital Content is available in the text., Background and Purpose: Stroke is reported as a consequence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in several reports. However, data are sparse regarding the details of these patients in a multinational and large scale. Methods: We conducted a multinational observational study on features of consecutive acute ischemic stroke, intracranial hemorrhage, and cerebral venous or sinus thrombosis among SARS-CoV-2–infected patients. We further investigated the risk of large vessel occlusion, stroke severity as measured by the National Institutes of Health Stroke Scale, and stroke subtype as measured by the TOAST (Trial of ORG 10172 in Acute Stroke Treatment) criteria among patients with acute ischemic stroke. In addition, we explored the neuroimaging findings, features of patients who were asymptomatic for SARS-CoV-2 infection at stroke onset, and the impact of geographic regions and countries’ health expenditure on outcomes. Results: Among the 136 tertiary centers of 32 countries who participated in this study, 71 centers from 17 countries had at least 1 eligible stroke patient. Of 432 patients included, 323 (74.8%) had acute ischemic stroke, 91 (21.1%) intracranial hemorrhage, and 18 (4.2%) cerebral venous or sinus thrombosis. A total of 183 (42.4%) patients were women, 104 (24.1%) patients were

Published
2021

34. Gender disparity versus equality in acute stroke: a Middle Eastern country hospital-based study.

Author

George, John, Aref, Hany, Nasser, Azza Abdel, Nasef, Ayman, Elbassiouny, Ahmed, and Roushdy, Tamer

Subjects
*STROKE units, *GENDER inequality, *ISCHEMIC stroke, *GENDER differences (Sociology), *HOSPITALIZATION insurance, *ATRIAL fibrillation
Abstract

Background: Acute stroke management is well-established in developed countries with no gender difference. Yet, in developing countries there are reports on gender disparity in medical services including stroke services. Egypt, a developing low–middle-income country, heavily populated, in the Middle East is a good example to answer whether acute ischemic stroke service is provided equally to males and females or there is disparity in risk factors, onset to door (OTD), door to needle (DTN), and outcome. The current study was prospective observational analytical hospital-based study, on acute ischemic stroke cases admitted to Nasr city insurance hospital stroke unit between September 2020 and September 2022. Results: 350 cases were included, 257 males and 93 females. Hypertension was the commonest risk factor 66% males and 81% females P = 0.011, atrial fibrillation was predominant in females P < 0.001, smoking was predominant in males P < 0.001. Median OTD in hours was 8.0 among both genders with minimum zero and maximum 96 h in males compared to minimum 1 and maximum 120 h in females, DTN was around 30 min with no significant difference. Median NIHSS on which rtPA was administered was 12.5 (6–13) in females compared to 10 (6–12) in males. Males who did not receive rtPA had a better mRS on discharge and on 90 days P = 0.01, 0.009, respectively, while there was no significant difference on discharge and 90 days between both genders on receiving rtPA. Conclusions: No gender disparity was found in DTN, discharge outcome, and 90 days among rtPA recipients. Females tended to have higher NIHSS and relatively delayed presentation to ER with less favorable outcome at discharge and 90 days in case of not receiving rtPA. Encouraging earlier arrival and conducting awareness campaigns for risk factors management is warranted. [ABSTRACT FROM AUTHOR]

Published
2023
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36. Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

Author

Nogueira, Raul, Qureshi, Muhammad, Abdalkader, Mohamad, Martins, Sheila Ouriques, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama Yassin, Sathya, Anvitha, Czlonkowska, Anna, Tsivgoulis, Georgios, Aguiar de Sousa, Diana, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James, Kõrv, Janika, Biller, Jose, Liang, Conrad, Sangha, Navdeep, Zha, Alicia, Czap, Alexandra, Holmstedt, Christine Anne, Turan, Tanya, Ntaios, George, Malhotra, Konark, Tayal, Ashis, Loochtan, Aaron, Ranta, Annamarei, Mistry, Eva, Alexandrov, Anne, Huang, David, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil, Mohammaden, Mahmoud, Frankel, Michael, Bila Lamou, Eric Guemekane, Aref, Hany, Elbassiouny, Ahmed, Hassan, Farouk, Menecie, Tarek, Mustafa, Wessam, Shokri, Hossam, Roushdy, Tamer, Sarfo, Fred, Alabi, Tolulope Oyetunde, Arabambi, Babawale, Nwazor, Ernest, Sunmonu, Taofiki Ajao, Wahab, Kolawole, Yaria, Joseph, Mohammed, Haytham Hussein, Adebayo, Philip, Riahi, Anis, Sassi, Samia Ben, Gwaunza, Lenon, Ngwende, Gift Wilson, Sahakyan, David, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj Durai, Sylaja, Pn, Usman, Fritz Sumantri, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Horev, Anat, Reznik, Anna, Sivan Hoffmann, Rotem, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshiki, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonoda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Kondybayeva, Aida, Faizullina, Kamila, Kamenova, Saltanat, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Jin Soo, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Sohn, Sung Il, Young, Chang Jun, Ahdab, Rechdi, Wan Zaidi, Wan Asyraf, Aziz, Zariah Abdul, Basri, Hamidon Bin, Chung, Law Wan, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal, Imam, Yahia Zakaria, Akhtar, Naveed, Pineda-Franks, Maria Carissa, Co, Christian Oliver, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Venketasubramanian, Narayanaswamy, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Akil, Esref, Aykaç, Özlem, Ozdemir, Atilla Ozcan, Giray, Semih, Hussain, Syed Irteza, John, Seby, Le Vu, Huynh, Tran, Anh Duc, Nguyen, Huy Hoang, Nhu Pham, Thong, Nguyen, Thang Huy, Nguyen, Trung Quoc, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, de Blauwe, Sofie, Vanhooren, Geert, de Raedt, Sylvie, Dusart, Anne, Lemmens, Robin, Ligot, Noemie, Pierre Rutgers, Matthieu, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedeković, Marina Roje, Budincevic, Hrvoje, Cindric, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, František, Karpowic, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Daniel, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henryk, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurák, Lubomír, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Krarup Christensen, Hanne, Drenck, Nicolas, Klingenberg Iversen, Helle, Simonsen, Claus, Truelsen, Thomas Clement, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emilie, Ondze, Basile, Peres, Roxane, Pico, Fernando, Piotin, Michel, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nino, Tsiskaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Götz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Klivenyi, Peter, Szapary, Laszlo, Tarkanyi, Gabor, Adami, Alessandro, Bandini, Fabio, Calabresi, Paolo, Frisullo, Giovanni, Renieri, Leonardo, Sangalli, Davide, Pirson, Anne, Uyttenboogaart, Maarten, van den Wijngaard, Ido, Kristoffersen, Espen Saxhaug, Brola, Waldemar, Fudala, Małgorzata, Horoch-Lyszczarek, Ewa, Karlinski, Michal, Kazmierski, Radoslaw, Kram, Pawel, Rogoziewicz, Marcin, Kaczorowski, Rafal, Luchowski, Piotr, Sienkiewicz-Jarosz, Halina, Sobolewski, Piotr, Fryze, Waldemar, Wisniewska, Anna, Wiszniewska, Malgorzata, Ferreira, Patricia, Ferreira, Paulo, Fonseca, Luisa, Marto, João Pedro, Pinho E Melo, Teresa, Nunes, Ana Paiva, Rodrigues, Miguel, Tedim Cruz, Vítor, Falup-Pecurariu, Cristian, Krastev, Georgi, Mako, Miroslav, de Leciñana, María Alonso, Arenillas, Juan, Ayo-Martin, Oscar, Cruz Culebras, Antonio, Tejedor, Exuperio Diez, Montaner, Joan, Pérez-Sánchez, Soledad, Tola Arribas, Miguel Angel, Rodriguez Vasquez, Alejandro, Mayza, Michael, Bernava, Gianmarco, Brehm, Alex, Machi, Paolo, Fischer, Urs, Gralla, Jan, Michel, Patrik, Psychogios, Marios-Nikos, Strambo, Davide, Banerjee, Soma, Krishnan, Kailash, Kwan, Joseph, Butt, Asif, Catanese, Luciana, Demchuk, Andrew, Field, Thalia, Haynes, Jennifer, Hill, Michael, Khosravani, Houman, Mackey, Ariane, Pikula, Aleksandra, Saposnik, Gustavo, Scott, Courtney Anne, Shoamanesh, Ashkan, Shuaib, Ashfaq, Yip, Samuel, Barboza, Miguel, Barrientos, Jose Domingo, Portillo Rivera, Ligia Ibeth, Gongora-Rivera, Fernando, Novarro-Escudero, Nelson, Blanco, Anmylene, Abraham, Michael, Alsbrook, Diana, Altschul, Dorothea, Alvarado-Ortiz, Anthony, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Brereton, Charmaine, Castonguay, Alicia, Chaturvedi, Seemant, Chaudry, Saqib, Choe, Hana, Choi, Jae, Dharmadhikari, Sushrut, Desai, Kinjal, Devlin, Thomas, Doss, Vinodh, Edgell, Randall, Etherton, Mark, Farooqui, Mudassir, Frei, Don, Gandhi, Dheeraj, Grigoryan, Mikayel, Gupta, Rishi, Hassan, Ameer, Helenius, Johanna, Kaliaev, Artem, Kaushal, Ritesh, Khandelwal, Priyank, Khawaja, Ayaz, Khoury, Naim, Kim, Benny, Kleindorfer, Dawn, Koyfman, Feliks, Lee, Vivien, Leung, Lester, Linares, Guillermo, Linfante, Italo, Lutsep, Helmi, Macdougall, Lisa, Male, Shailesh, Malik, Amer, Masoud, Hesham, Mcdermott, Molly, Mehta, Brijesh, Min, Jiangyong, Mittal, Manoj, Morris, Jane, Multani, Sumeet, Nahab, Fadi, Nalleballe, Krishna, Nguyen, Claude, Novakovic-White, Roberta, Ortega-Gutierrez, Santiago, Rahangdale, Rahul, Ramakrishnan, Pankajavalli, Romero, Jose Rafael, Rost, Natalia, Rothstein, Aaron, Ruland, Sean, Shah, Ruchir, Sharma, Malveeka, Silver, Brian, Simmons, Marc, Singh, Abhishek, Starosciak, Amy, Strasser, Sheryl, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny, Voetsch, Barbara, Balaguera, Oscar, Pujol Lereis, Virginia, Luraschi, Adriana, Almeida, Marcele Schettini, Cardoso, Fabricio Buchdid, Conforto, Adriana, de Deus Silva, Leonardo, Varrone Giacomini, Luidia, Oliveira Lima, Fabricio, Longo, Alexandre, Magalhães, Pedro, Martins, Rodrigo Targa, Mont'Alverne, Francisco, Mora Cuervo, Daissy Liliana, Costa Rebello, Leticia, Valler, Lenise, Zetola, Viviane Flumignan, Lavados, Pablo, Navia, Victor, Olavarría, Verónica, Almeida Toro, Juan Manuel, Amaya, Pablo Felipe Ricardo, Bayona, Hernan, Corredor, Angel, Rivera Ordonez, Carlos Eduardo, Mantilla Barbosa, Diana Katherine, Lara, Osvaldo, Patiño, Mauricio, Diaz Escobar, Luis Fernando, Dejesus Melgarejo Fariña, Donoband Edson, Cardozo Villamayor, Analia, Zelaya Zarza, Adolfo Javier, Barrientos Iman, Danny Moises, Rodriguez Kadota, Liliana, Campbell, Bruce, Hankey, Graeme, Hair, Casey, Kleinig, Timothy, Ma, Alice, Tomazini Martins, Rodrigo, Sahathevan, Ramesh, Thijs, Vincent, Salazar, Daniel, Yuan-Hao Wu, Teddy, Haussen, Diogo, Liebeskind, David, Yavagal, Dileep, Jovin, Tudor, Zaidat, Osama, Nguyen, Thanh, Magalhães, Pedro S.C., Emory University School of Medicine, Emory University [Atlanta, GA], Boston University School of Medicine (BUSM), Boston University [Boston] (BU), Lille Neurosciences & Cognition - U 1172 (LilNCog), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Max Super Speciality Hospital -Saket [New Delhi, Inde] (Max Saket), Dupuis, Christine, Lille Neurosciences & Cognition - U 1172 (LilNCog (ex-JPARC)), and Repositório da Universidade de Lisboa

Subjects
medicine.medical_specialty, MESH: Pandemics, HSJ NEU, Cross-sectional study, medicine.medical_treatment, [SDV]Life Sciences [q-bio], SVIN COVID-19 Global Stroke Registry, MESH: Hospitalization, 030204 cardiovascular system & hematology, Article, MESH: Stroke, COVID-19, cross-sectional studies, hospitalization, humans, pandemics, retrospective studies, SARS-CoV-2, stroke, 03 medical and health sciences, 0302 clinical medicine, MESH: Cross-Sectional Studies, Pandemic, Medicine, Humans, MESH: COVID-19, Thrombolytic Therapy, MESH: SARS-CoV-2, Stroke, Pandemics, Retrospective Studies, MESH: Thrombolytic Therapy, Rehabilitation, MESH: Humans, business.industry, Retrospective cohort study, MESH: Retrospective Studies, medicine.disease, Thrombolysis, Confidence interval, 3. Good health, Hospitalization, [SDV] Life Sciences [q-bio], Clinical research, Cross-Sectional Studies, Emergency medicine, Observational study, Neurology (clinical), business, 030217 neurology & neurosurgery
Abstract

© 2021 American Academy of Neurology, Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results: There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95% confidence interval [CI] -11.7 to -11.3, p < 0.0001) decline. There were 13,334 IVT therapies in the 4 months preceding compared to 11,570 procedures during the pandemic, representing a 13.2% (95% CI -13.8 to -12.7, p < 0.0001) drop. Interfacility IVT transfers decreased from 1,337 to 1,178, or an 11.9% decrease (95% CI -13.7 to -10.3, p = 0.001). Recovery of stroke hospitalization volume (9.5%, 95% CI 9.2-9.8, p < 0.0001) was noted over the 2 later (May, June) vs the 2 earlier (March, April) pandemic months. There was a 1.48% stroke rate across 119,967 COVID-19 hospitalizations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was noted in 3.3% (1,722/52,026) of all stroke admissions. Conclusions: The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months.

Published
2021
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37. Stroke services in Africa: What is there and what is needed.

Author

Roushdy, Tamer, Aref, Hany, Kesraoui, Selma, Temgoua, Michael, Nono, Kiatoko Ponte, Gebrewold, Meron Awraris, Peter, Waweru, Gopaul, Urvashy, Belahsen, Mohammed Faouzi, Ben-Adji, Djibrilla, Melifonwu, Rita, Pugazhendhi, Sanjeev, Woodcock, Noëmie, Mohamed, Muhyadin Hassan, Rossouw, Anastasia, Matuja, Sarah, Ruanda, Mark Koba, Mhiri, Chokri, Saylor, Deanna, and Nahas, Nevine El

Subjects
*STROKE units, *SECONDARY prevention, *INTERNET surveys, *MEDICAL care
Abstract

Background: Over the past few years, the incidence and prevalence of stroke has been rising in most African countries and has been reported as one of the leading causes of morbidity and mortality. To study this problem, we need to realize the quality and availability of stroke care services as a priori to improve them. Methods and Results: In this study, we investigated the availability of different stroke-related services in 17 countries from different African regions. An online survey was conducted and fulfilled by stroke specialists and included primary prevention, acute management, diagnostic tools, medications, postdischarge services, and stroke registries. The results showed that although medications for secondary prevention are available, yet many other services are lacking in various countries. Conclusion: This study displays the deficient aspects of stroke services in African countries as a preliminary step toward active corrective procedures for the improvement of stroke-related health services. [ABSTRACT FROM AUTHOR]

Published
2022
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39. Micro-RNA in a Sample of Egyptian Patients with Incidental Cerebral Small Vessel Disease.

Author

Maged, Mohamed, El Nahas, Nevine, Aref, Hany, Kilany, Ayman, Hamid, Eman, and Fathy, Mai

Subjects
CEREBRAL small vessel diseases, EGYPTIANS, MICRORNA, LACUNAR stroke
Abstract

Background: Cerebral small vessel disease (CSVD) causes great disability at increasing age such as cognitive impairment, gait and sphincteric problems affecting a person's quality of life. That is why it's important to detect and manage early. The aim of this study is to investigate certain micro-RNA in Egyptian patients with CSVD. Methods: Thirty patients with CSVD were compared to thirty controls undergoing assessment for cognitive, gait and sphincteric control together with MRI brain and blood sampling for miRNA (miR-409-3p, miR-502-3p, miR-486-5p and miR-451a). Results: No difference regarding age, gender or risk factors, yet MiRNA-451a was up-regulated in cases with a median fold change of 3.4 in comparison to healthy controls. Conclusion: The studied microRNA can may have a role in pathophysiology of CSVD. [ABSTRACT FROM AUTHOR]

Published
2024
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40. Borderzone Infarction and Small Vessel Disease in a Sample of Egyptian Stroke Patients: Differences and Similarities.

Author

El Nahas, Nevine, Aref, Hany, Alloush, Taha, Fahmy, Nagia, Ahmed, Khaled, El Basiouny, Ahmed, Tork, Mohamed, Elbokl, Ahmed, Shokri, Hossam, El Nahas, Nevine M, Aref, Hany M, Alloush, Taha K, Fahmy, Nagia A, Ahmed, Khaled A, El Basiouny, Ahmed A, Tork, Mohamed A, Elbokl, Ahmed M, and Shokri, Hossam M

Subjects
*LACUNAR stroke, *STROKE, *INFARCTION, *STROKE patients, *ISCHEMIC stroke, *MAGNETIC resonance imaging, *SECONDARY prevention, *CEREBRAL small vessel diseases, *NIH Stroke Scale, *NEURORADIOLOGY
Abstract

Background: The anatomical location of white matter hyperintense lesions in small vessel disease are apparently similar to those of borderzone infarction. The objective of this study is to find clinical and radiological points of differentiation between the two vascular disorders in a sample of Egyptian patients which might have an impact on primary and secondary prevention.Methods: Ischemic stroke patients with white matter lesions were categorized into two groups: small vessel disease and borderzone infarctions. NIHSS was done on admission. Risk factor profile was reported, and investigations done including: HbA1C, lipid profile, CRP, ECG, echocardiography, carotid duplex, brain MRI, MRA and MR perfusion study.Results: 46 patients completed the study, 29 with SVD and 17 with BZI. Smoking, hypertension and recurrent stroke were more common in borderzone infarctions, but only diabetes was significantly higher (p = 0.047). Limb shaking was more observed in borderzone infarctions (p = 0.049). Radiologically: lacunar pattern was observed more in small vessel disease, while rosary pattern was more in borderzone infarctions (p = 0.04). FLAIR symmetrical lesions and microbleeds were more significant in small vessel disease (p = <0.001; 0.048, respectively). Perfusion study time to peak denoted evidence of significant hypoperfusion in all regions of interest in borderzone infarctions.Conclusion: Limb shaking, retinal claudication or syncope, with MRI showing rosary pattern of white matter hyperintensity, few microbleeds and markedly impaired perfusion favor the diagnosis of borderzone infarctions. On the other hand, presence of lacunae, FLAIR showing symmetrical WMH and microbleeds with minimal or no perfusion deficit suggests the diagnosis of small vessel disease. [ABSTRACT FROM AUTHOR]

Published
2021
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42. A pilot study of the ticagrelor role in ischemic stroke secondary prevention.

Author

Zeinhom, Mohamed G., Aref, Hany M., El-khawas, Hala, Roushdy, Tamer M., Shokri, Hossam M., and elbassiouny, Ahmed

Subjects
*STROKE, *ISCHEMIC stroke, *SECONDARY prevention, *STROKE patients, *TICAGRELOR, *PLATELET aggregation inhibitors
Abstract

Introduction: Ticagrelor is one of the most recent antiplatelet drugs used to treat ischemic heart disease. Its efficacy may equal or exceed aspirin in improving clinical outcomes in patients with acute ischemic stroke who are ineligible for rt-PA. Aim of the Work: We aimed at evaluating the safety (as a primary endpoint) and efficacy (as a secondary endpoint) of a 180 mg loading dose of ticagrelor given within 9 h from the onset of first-ever ischemic stroke. Methods: We conducted an open-label, randomized prospective controlled clinical trial between May 2019 and September 2020 on patients who presented with their first-ever ischemic stroke and were recruited from the emergency department, of Kafr el-sheik University Hospitals, Egypt. Eligible patients randomly received aspirin or ticagrelor loading and maintenance doses. Treatment began within 9 h of stroke onset. Results: Aspirin was given to 84 patients; ticagrelor was given to 85. There was no significant difference between the 2 groups regarding the hemorrhagic and nonhemorrhagic complications. Patients who received ticagrelor had a better outcome regarding NIHSS improvement at 2 days and 1 week or discharge and a favorable mRS score after 1 week or discharge and at 90-day follow-up. Conclusion: Ticagrelor was noninferior to aspirin regarding safety profile. Compared with aspirin, ticagrelor had a better clinical outcome based on NIHSS and mRS in first-ever acute ischemic stroke patients who received it within 9 h from symptom onset, leading to a shorter hospital stay. [ABSTRACT FROM AUTHOR]

Published
2022
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45. Pre-hospital causes for delayed arrival in acute ischemic stroke before and during the COVID-19 pandemic: A study at two stroke centers in Egypt.

Author

Aref, Hany M., Shokri, Hossam, Roushdy, Tamer M., Fathalla, Fatma, and El Nahas, Nevine M.

Subjects
*ISCHEMIC stroke, *COVID-19 pandemic, *MEDICAL personnel, *PATIENTS' attitudes, *COVID-19, *TREATMENT delay (Medicine), *PANDEMICS
Abstract

Background: In the current study we investigated the causes of pre-hospital delay as this can compromise the patient's chance to receive thrombolytic therapy and thus impact stroke outcome. Methods: We surveyed 254 patients regarding reasons for delayed and early arrival to hospital after acute ischemic stroke. The survey was performed over five months, spanning a period pre- and during COVID-19 (between December 7, 2019 and May 10, 2020). Results: A total of 71.2% of patients arrived beyond four hours of onset of ischemic stroke. The commonest cause for delay pre-Covid-19 was receiving treatment in a non-stroke hospital, while that during COVID-19 was fear of infection and lock down issues. Not realizing the urgency of the condition and stroke during sleep were common in both periods. Early arrival because of the patient's previous experience with stroke accounted for approximately 25% of cases in both periods. The effect of media was more evident during COVID-19, accounting for 47.7% of cases. Conclusion: Pre-hospital delay secondary to misperception of the urgency of stroke and management in a non-stroke hospital reflect the lack of awareness among the public and medical staff. This concept is emphasized by early arrival secondary to previous experience with stroke and the pronounced effect of media in the time of COVID-19. [ABSTRACT FROM AUTHOR]

Published
2021
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48. Factors related to time of stroke onset versus time of hospital arrival: A SITS registry-based study in an Egyptian stroke center.

Author

Shokri, Hossam M., El Nahas, Nevine M., Aref, Hany M., Dawood, Noha L., Abushady, Eman M., Abd Eldayem, Eman H., Georgy, Shady S., Zaki, Amr S., Bedros, Rady Y., Wahid El Din, Mona M., and Roushdy, Tamer M.

Subjects
STROKE, HEALTH services accessibility, THROMBOLYTIC therapy, STROKE patients, REHABILITATION centers
Abstract

Background: High-quality data on time of stroke onset and time of hospital arrival is required for proper evaluation of points of delay that might hinder access to medical care after the onset of stroke symptoms. Purpose: Based on (SITS Dataset) in Egyptian stroke patients, we aimed to explore factors related to time of onset versus time of hospital arrival for acute ischemic stroke (AIS). Material and methods: We included 1,450 AIS patients from two stroke centers of Ain Shams University, Cairo, Egypt. We divided the day to four quarters and evaluated relationship between different factors and time of stroke onset and time of hospital arrival. The factors included: age, sex, duration from stroke onset to hospital arrival, type of management, type of stroke (TOAST classification), National Institute of Health Stroke Scale (NIHSS) on admission and favorable outcome modified Rankin Scale (mRS ≤2). Results: Pre-hospital: highest stroke incidence was in the first and fourth quarters. There was no significant difference in the mean age, sex, type of stroke in relation to time of onset. NIHSS was significantly less in onset in third quarter of the day. Percentage of patients who received thrombolytic therapy was higher with onset in the first 2 quarters of the day (p = <0.001). In-hospital: there was no difference in percentage of patients who received thrombolytic therapy nor in outcome across 4 quarters of arrival to hospital. Conclusion: Pre-hospital factors still need adjustment to improve percentage of thrombolysis, while in-hospital factors showed consistent performance. [ABSTRACT FROM AUTHOR]

Published
2020
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49. MIRNA-133A IN ACUTE MYOCARDIAL INFARCTION: MUCH MORE THAN A CARDIAC BIOMARKER.

Author

Mahmoud, Adel H, Ibrahim, Alaa, Ali, Lamia H, and Aref Hany T Taha, Hosam M

Subjects
MYOCARDIAL infarction, CORONARY disease, MYOCARDIAL ischemia, NON-coding RNA, VENTRICULAR remodeling, MYOCARDIAL reperfusion, SMALL interfering RNA
Abstract

Ischemic heart disease is a leading cause of morbidity and mortality worldwide. Infarct size is the single most important predictor of adverse ventricular remodeling, and it is linearly dependent upon the amount of myocardial salvage by reperfusion. Lack of timely reperfusion, due to ineffective treatment or delayed presentation, leads to an unfavorable prognosis. Micro Ribo Nucleic Acids (miRNAs) are small non-coding RNAs ~22 nucleotides in length that function as guide molecules in RNA silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all developmental and pathological processes in animals. The biogenesis of miRNAs is under tight control, and their dysregulation is associated with many human diseases. In cardiac diseases, including myocardial infarction (MI), expression of cardiac miRNAs is markedly altered which leads to deleterious effects associated with heart injury, arrhythmia, increased apoptosis, fibrosis, hypertrophy, and tissue remodeling. In acute MI, circulating levels of cardiac miRNAs are significantly elevated making them a promising diagnostic marker for early diagnosis of acute MI. The great cardio-specific capacity of these miRNAs is very helpful for enhancing regenerative properties and survival of stem cell and cardiac progenitor transplants and for reprogramming of mature non-cardiac cells to cardiomyocytes. in this review we will illustrate the role of miRNA-133a in human heart and its therapeutic implications. [ABSTRACT FROM AUTHOR]

Published
2021

50. Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region—Results from the Safe Implementation of Treatments in Stroke (SITS)–Middle-East and North African (MENA).

Author

Rukn, Suhail Al, Mazya, Michael V, Hentati, Faycal, Sassi, Samia Ben, Nabli, Fatma, Said, Zakharia, Faouzi, Belahsen, Hashim, Husnain, Abd-Allah, Foad, Mansouri, Benhan, Kesraoui, Selma, Gebeily, Souheil, Abdulrahman, Husen, Akhtar, Naveed, Ahmed, Niaz, Wahlgren, Nils, Aref, Hany, Almekhlafi, Mohammed, and Moreira, Tiago

Subjects
STROKE, STROKE units, LACUNAR stroke, LONGITUDINAL method, ATRIAL fibrillation, SCIENTIFIC observation
Abstract

Background and methods: Stroke incidence and mortality are reported to have increased in the Middle-East and North African (MENA) countries during the last decade. This was a prospective observational study to examine the baseline characteristics of stroke patients in the MENA region and to compare the MENA vs. the non-MENA stroke cohort in the Safe Implementation of Treatments in Stroke (SITS) International Registry. Results: Of the 13,822 patients with ischemic and hemorrhagic stroke enrolled in the SITS-All Patients Protocol between June 2014 and May 2016, 5897 patients (43%) were recruited in MENA. The median onset-to-door time was 5 h (IQR: 2:20–13:00), National Institutes of Health Stroke Scale (NIHSS) score was 8 (4–13) and age was 65 years (56–76). Hypertension (66%) and diabetes (38%) were the prevailing risk factors; large artery stenosis > 50% (25.3%) and lacunar strokes (24.1%) were the most common ischemic stroke etiologies. In comparison, non-MENA countries displayed an onset-to-door time of 5:50 h (2:00–18:45), a median of NIHSS 6 (3–14), and a median age of 66 (56–76), with other large vessel disease and cardiac embolism as the main ischemic stroke etiologies. Hemorrhagic strokes (10%) were less common compared to non-MENA countries (13.9%). In MENA, only a low proportion of patients (21%) was admitted to stroke units. Conclusions: MENA patients are slightly younger, have a higher prevalence of diabetes and slightly more severe ischemic strokes, commonly of atherosclerotic or microvascular etiology. Admission into stroke units and long-term follow-up need to be improved. It is suspected that cardiac embolism and atrial fibrillation are currently underdiagnosed in MENA countries. [ABSTRACT FROM AUTHOR]

Published
2019
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