17 results on '"Balikji, Jessica"'
Search Results
2. COVID-19 Lockdown Effects on Mood: Impact of Sex, Age, and Underlying Disease.
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Kiani, Pantea, Hendriksen, Pauline A., Balikji, Jessica, Severeijns, Noortje R., Sips, Annabel S. M., Bruce, Gillian, Garssen, Johan, and Verster, Joris C.
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- 2023
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3. Immune Fitness, Migraine, and Headache Complaints in Individuals with Self-Reported Impaired Wound Healing
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Balikji,Jessica, Mackus,Marlou, Garssen,Johan, Hoogbergen,Maarten M, and Verster,Joris C
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International Journal of General Medicine - Abstract
Jessica Balikji,1 Marlou Mackus,1 Johan Garssen,1,2 Maarten M Hoogbergen,3 Joris C Verster1,4 1Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, 3584 CG, the Netherlands; 2Division of Plastic Surgery, Catharina Ziekenhuis, Eindhoven, 5623 EJ, the Netherlands; 3Global Centre of Excellence Immunology, Nutricia Danone Research, Utrecht, 3584 CT, the Netherlands; 4Centre for Human Psychopharmacology, Swinburne University, Melbourne, VIC, 3122, AustraliaCorrespondence: Joris C Verster, Tel +31 30 253 6909, Email j.c.verster@uu.nlBackground: Having chronic wounds and impaired wound healing are associated with psychological distress. The current study aims to evaluate migraine and headache complaints in young adults with self-reported impaired wound healing.Methods: A survey was conducted among N=1935 young adults (83.6% women), 18â 30 years old, living in the Netherlands. Wound healing status was verified, immune fitness was assessed using a single-item rating scale, and ID Migraine was completed. In addition, several questions were answered on past yearâs headache experiences (including frequency, quantity, type, location, and severity).Results: In both the control group (p < 0.001) and the IWH group (p = 0.002) immune fitness was significantly lower among those that reported headaches compared to those that reported no headaches. Individuals with self-reported impaired wound healing (IWH) scored significantly higher on the ID Migraine scale, and individuals of the IWH group scored significantly more often positive for migraine (ie, an ID Migraine score ⥠2). They reported a younger age of onset of experiencing headaches, and significantly more often reported having a beating or pounding headache than the control group. Compared to the control group, the IWH group reported being significantly more limited in their daily activities compared to the control group.Conclusion: Headaches and migraines are more frequently reported by individuals with self-reported impaired wound healing, and their reported immune fitness is significantly poorer compared to healthy controls. These headache and migraine complaints significantly limit them in their daily activities.Keywords: headache, migraine, impaired wound healing, wound infection, slow healing wounds, chronic wounds, immune fitness
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- 2023
4. COVID-19 Lockdown Effects on Mood, Alcohol Consumption, Academic Functioning, and Perceived Immune Fitness: Data from Young Adults in Germany
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Koyun, Anna Helin, Hendriksen, Pauline, kiani, pantea, Agnese, Fabio, Balikji, Jessica, Stock, Ann-Kathrin, Verster, Joris, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology
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Information Systems and Management ,alcohol consumption ,mood ,academic performance ,COVID-19 ,Computer Science Applications ,lockdown ,perceived immune fitness ,quality of life ,Germany ,social interactions ,sleep ,Information Systems - Abstract
Recently, a study was conducted in the Netherlands to evaluate the impact of the coronavirus disease (COVID-19) pandemic and its associated lockdown periods on academic functioning, mood, and health correlates, such as alcohol consumption. The Dutch study revealed that lockdowns were associated with significantly poorer mood and reductions in perceived immune fitness. Overall, a reduction in alcohol consumption during lockdown periods was shown. Academic functioning in terms of self-reported performance was unaffected. However, a significant reduction in interactions with other students and teachers was reported. However, there was considerable variability among students; both increases and reductions in alcohol consumption were reported, as well as both improvements and poorer academic functioning during periods of lockdown. The aim of the current online study was to replicate these findings in Germany. To achieve this, a slightly modified version of the survey was administered among young adults (aged 18 to 35 years old) in Germany. The survey assessed possible changes in self-reported academic functioning, mood, and health correlates, such as smoking and alcohol consumption, perceived immune functioning, and sleep quality during periods of lockdown as compared to periods with no lockdowns. Retrospective assessments were made for five periods, including (1) ‘BP’ (the period before the COVID-19 pandemic), (2) ‘L1’ (the first lockdown period, March–May 2020), (3) ‘NL1’ (the first no-lockdown period, summer 2020), (4) ‘L2’ (the second lockdown, November 2020 to May 2021), and (5) ‘NL2’ (the second no-lockdown period, summer 2021). This article describes the content of the survey and the corresponding dataset. The survey was completed by 371 participants. Dataset: The dataset is submitted as a Supplementary File. Dataset License: CC0.
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- 2022
5. Insomnia Complaints and Perceived Immune Fitness in Young Adults with and without Self-Reported Impaired Wound Healing
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Balikji, Jessica, Hoogbergen, Maarten, garssen, johan, Roth, Thomas, Verster, Joris, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology
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Male ,Medicine(all) ,insomnia ,slow healing wounds ,wound healing ,General Medicine ,sleep complaints ,fatigue ,perceived immune fitness ,wound infection ,Young Adult ,Sleep Initiation and Maintenance Disorders ,Humans ,Female ,Self Report ,Sleep - Abstract
Background and Objectives: Adequate sleep and an effective immune system are both essential to maintain a good health status. The current study aimed to determine the nature of insomnia complaints and perceived immune fitness among Dutch young adults with and without self-reported impaired wound healing. Materials and Methods: A total of (n = 2033) Dutch students (83.8% women) completed an online survey. Perceived immune fitness was assessed with a single-item scale and insomnia complaints with the SLEEP-50 insomnia subscale. The sample comprised a control group without self-reported impaired wound healing (n = 1622), a wound infection (WI) group (n = 69), a slow healing wounds (SHW) group (n = 250), and a COMBI group that experienced both WI and SHW (n = 92). Results: Comparisons with the control group revealed that individuals of the SHW and COMBI groups reported significantly poorer perceived immune functioning, increased insomnia complaints and daytime fatigue, and poorer sleep quality. Conclusions: Individuals with self-reported impaired wound healing have a poorer perceived immune functioning, increased insomnia complaints, daytime fatigue, and poorer sleep quality.
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- 2022
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6. Pandemic Preparedness: The Potential Advantage of Medicines That Prevent Acute Side Effects of Vaccination, SARS-CoV-2 as an Example
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kiani, pantea, Balikji, Jessica, garssen, johan, Verster, Joris, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology
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side effects ,prevention ,SARS-CoV-2 ,COVID-19 ,reactogenicity ,pandemic preparedness ,adverse reactions ,vaccination ,SJP-003 ,medicines - Abstract
Vaccination against SARS-CoV-2 is an important and essential strategy to combat the 2019 coronavirus disease (COVID-19) pandemic. Vaccination has shown to be effective in reducing the spread of SARS-CoV-2, reducing the chances of becoming infected and developing severe COVID-19, and reducing hospitalization and mortality rates. However, the vaccinations against SARS-CoV-2 are accompanied by undesirable side effects which may be in part responsible for a reduction in the willingness to become vaccinated. At this moment (June 2022), 24.3% of the US adult population (18+ years old) is not fully vaccinated against SARS-CoV-2, and 49.5% did not receive their follow-up booster vaccination. The most important motives for refusing vaccination are the unknown long-term side effects and the known acute side effects of vaccination. Here, we discuss the importance of recognizing the impact of this reactogenicity on individuals’ willingness to vaccinate and how the development of effective and safe medicines that prevent or mitigate the unwanted side effects of the vaccination may help to increase the willingness to vaccinate.
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- 2022
7. Inattention, Impulsivity, and Hyperactivity among Individuals with Self-Reported Impaired Wound Healing
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Balikji, Jessica, Hoogbergen, Maarten M., garssen, johan, Verster, Joris, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology
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impaired wound healing ,perceived immune fitness ,General Neuroscience ,slow healing wounds ,Neuroscience(all) ,ADHD ,attention deficit ,impulsivity ,wound infection ,hyperactivity - Abstract
Background: Inattention and impulsivity are common causes of accidents and injury. The aim of the current study was to examine the level of attention deficit (AD), hyperactivity, and impulsivity (HI) in individuals with and without self-reported impaired wound healing (IWH). Methods: A survey was conducted among N = 773 Dutch young adults, 18–30 years old. N = 198 were allocated to the IWH group and N = 575 to the control group. All participants completed the Attention Deficit Hyperactivity Disorder (ADHD) Rating Scale. Results: The analysis revealed that the IWH group has significantly higher scores on AD and HI, compared to the control group. Among the IWH group, 12.8% screened positive for AD (compared to 5.8% of the control group) and 14.0% screened positive for HI (compared to 7.4% of the control group). Conclusion: Clinically relevant increased inattention, impulsivity, and hyperactivity were observed among individuals with self-reported impaired wound healing.
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- 2022
8. Pandemic Preparedness: Maintaining Adequate Immune Fitness by Attaining a Normal, Healthy Body Weight
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kiani, pantea, Mulder, Kiki, Balikji, Jessica, Kraneveld, Aletta, garssen, johan, Verster, Joris, Afd Pharmacology, and Pharmacology
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Medicine(all) ,age ,SARS-CoV-2 ,COVID-19 ,pandemic preparedness ,sex ,body mass index ,General Medicine ,immune fitness ,bodyweight ,height - Abstract
In addition to developing effective medicines and vaccines, pandemic preparedness also comprises general health-related, behavioral, and psychological aspects related to being more resistant in the case of future pandemics. In the context of the 2019 coronavirus (COVID-19) pandemic, recent research revealed that reduced perceived immune fitness was the best predictor of reporting more frequent and more severe COVID-19 symptoms. Up until now (June 2022), during the COVID-19 pandemic, the majority of patients who have been hospitalized were characterized as being overweight. It is therefore essential to further evaluate the relationship between body mass index (BMI) and immune fitness. This was performed by analyzing pooled data from previously published studies, conducted among N = 8586 Dutch adults. It was hypothesized that attaining a normal, healthy body weight is associated with optimal perceived immune fitness. The analysis revealed that a deviation from normal weight (i.e., having a BMI outside the range of 18.5 to 24.9 kg/m2) was associated with significantly reduced perceived immune fitness, as assessed with the immune status questionnaire and a single item perceived immune fitness scale. The effects were significant for both underweight and overweight groups and most pronounced for the obese groups. The results suggest that attaining a normal, healthy body weight might significantly contribute to maintaining adequate perceived immune fitness. Therefore, attaining a normal body weight might be an essential component of pandemic preparedness and should be supported by creating awareness and promoting the importance of regular exercise and the consumption of healthy food.
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- 2022
9. The Impact of COVID-19 Lockdowns in Germany on Mood, Attention Control, Immune Fitness, and Quality of Life of Young Adults with Self-Reported Impaired Wound Healing.
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Balikji, Jessica, Koyun, Anna H., Hendriksen, Pauline A., Kiani, Pantea, Stock, Ann-Kathrin, Garssen, Johan, Hoogbergen, Maarten M., and Verster, Joris C.
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CONTROL (Psychology) , *YOUNG adults , *WOUND healing , *STAY-at-home orders , *ATTENTION control - Abstract
Background: Previous studies in Dutch young adults revealed that individuals with self-reported impaired wound healing reported poorer mood, increased inattention and impulsivity, poorer quality of life, and poorer immune fitness compared to healthy controls. Another study revealed that the negative impact of lockdowns during the 2019 coronavirus disease (COVID-19) pandemic was significantly more profound among the impaired wound healing group than the control group. The purpose of the current study was to replicate and extend these findings among young adults living in Germany. Methods: A retrospective, cross-sectional survey was conducted among N = 317 young adults living in Germany, 18–35 years old. They were allocated to the IWH group (N = 66) or the control group (N-251). Participants completed the Attention Control Scale, and mood, quality of life, and immune fitness were assessed with single-item ratings. All assessments were made for (1) the period before the COVID-19 pandemic, (2) the first lockdown period, March–May 2020, (3) the first no-lockdown period, summer 2020, (4) the second lockdown, November 2020 to May 2021, and (5) the second no-lockdown period, summer 2021. Results: The impaired wound healing group reported significantly poorer mood, quality of life, and immune fitness. The effects were evident before the pandemic. The impaired wound healing group scored significantly poorer on attention focusing, but no significant differences between the groups were found for attention shifting. During the pandemic, negative lockdown effects (i.e., further aggravation of mood and immune fitness and lower quality of life) were evident in both groups but significantly more profound in the impaired wound healing group. No differences between the groups were found for the no-lockdown periods. Conclusion: Individuals with self-reported impaired wound healing have significantly poorer mood, attention focusing, and immune fitness and report a poorer quality of life than healthy controls. The impact of COVID-19 lockdowns was significantly more profound in the impaired wound-healing group. [ABSTRACT FROM AUTHOR]
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- 2023
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10. Emotion Regulation and Mood during the COVID-19 Pandemic.
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Verster, Joris C., Hendriksen, Pauline A., Kiani, Pantea, Merlo, Agnese, Balikji, Jessica, Garssen, Johan, and Bruce, Gillian
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COVID-19 pandemic ,MOOD (Psychology) ,EMOTION regulation ,QUALITY of life ,COVID-19 - Abstract
The analysis revealed a model showing that immune fitness before the COVID-19 pandemic was the only predictor of the number (27.2%) and severity (33.1%) of COVID-19 symptoms during the pandemic [[19]]. Kiani et al. [[19]] investigated the relationship between immune fitness before the COVID-19 pandemic as a predictor of COVID-19 symptom severity once infected with SARS-CoV-2. The 2019 coronavirus disease (COVID-19) pandemic has had a significant negative impact on health, mood, and well-being [[1]]. Figure 3 shows the significant correlation between immune fitness before the COVID-19 pandemic and COVID-19 symptom severity during the pandemic. [Extracted from the article]
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- 2023
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11. Self-Reported Impaired Wound Healing in Young Adults and Their Susceptibility to Experiencing Immune-Related Complaints
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Balikji, Jessica, Hoogbergen, Maarten M., Garssen, Johan, Verster, Joris C., Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology
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Medicine(all) ,Slow healing wounds ,Immune fitness ,Wound infection ,Headache ,wound infection ,slow healing wounds ,immune functioning ,immune fitness ,headache ,General Medicine ,Immune functioning - Abstract
The current study examined to what extent individuals with wound infection (WI group), slow healing wounds (SHW group), or both (COMBI group) report poorer immune fitness and whether they experience immune-related complaints more often as compared to healthy participants (control group). Survey data from 3613 Dutch students was re-analyzed. Compared to the control group, perceived immune fitness was significantly lower by the SHW group (p < 0.001) and the COMBI group (p < 0.001), but no difference was found for the WI group (p = 0.059). Also, perceived immune fitness of the COMBI group was significantly worse compared to the WI group (p = 0.040). Compared to the control group, reduced immune fitness was reported to be significantly more frequently by the SHW group (p < 0.001) and the COMBI group (p < 0.001). Reduced immune fitness was significantly more common for the COMBI group compared to the SHW group (p = 0.011) and WI group (p = 0.001). Immune-related complaints such as headache, runny nose, coughing, sore throat, diarrhea, flu, and fever were significantly more frequently reported by individuals with impaired wound healing. The effects were most pronounced in the COMBI group, followed by the SHW group and a lesser extent the WI group. A highly significant correlation was found between perceived immune fitness and the percentage of individuals that reported impaired wound healing. In conclusion, the findings confirm that poorer immune functioning is characteristic for individuals with impaired wound healing. In follow-up studies, immune biomarkers analyses are needed to support patient-reported outcome measures.
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- 2022
12. The association of irritable bowel complaints and perceived immune fitness among individuals that report impaired wound healing: Supportive evidence for the gut-brain-skin axis
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Balikji, Jessica, Hoogbergen, Maarten M., Garssen, Johan, Verster, Joris C., Afd Pharmacology, and Pharmacology
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Diarrhea ,Irritable bowel syndrome ,Slow healing wounds ,Immune fitness ,Hepatology ,Wound infection ,Gastroenterology ,Pain ,Wound healing ,Constipation - Abstract
The gut–brain–skin axis is important in wound healing. The aim of this study was to investigate the association between experiencing irritable bowel syndrome (IBS) symptoms, perceived immune fitness, and impaired wound healing. N = 1942 Dutch students (mean (SD) age 21.3 (2.1), 83.6% women) completed an online survey. They were allocated to one of four groups: (1) control group (N = 1544), (2) wound infection (WI) group (N = 65), (3) slow healing wounds (SHW) group (N = 236), or (4) a combination group (COMBI), which experienced both WI and SHW (N = 87). Participants rated their perceived immune fitness on a scale ranging from very poor (0) to excellent (10), and the severity of IBS symptoms (constipation, diarrhea, and pain) was assessed with the Birmingham IBS Symptom Questionnaire. Compared to the control group, perceived immune fitness was significantly poorer for the SHW group (p < 0.001) and COMBI group (p < 0.001), but not for the WI group. Compared to the control group, constipation was reported significantly more frequently by the SHW group (p < 0.001) and the WI group (p = 0.012), diarrhea was reported significantly more frequent by the SHW group (p = 0.038) and the COMBI group (p = 0.004), and pain was reported significantly more frequent by the SHW group (p = 0.020) and COMBI group (p = 0.001). Correlations between IBS complaints and perceived immune fitness were statistically significant (p < 0.001), and also a highly significant and negative association was found between the percentage of participants that reported impaired wound healing and perceived immune fitness (r = −0.97, p < 0.001). In conclusion, among participants with self-reported impaired wound healing, IBS complaints were significantly more severe, and accompanied by a significantly reduced perceived immune fitness.
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- 2021
13. Impaired wound healing is associated with poorer mood and reduced perceived immune fitness during the COVID‐19 pandemic: A retrospective survey.
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Balikji, Jessica, Kiani, Pantea, Hendriksen, Pauline A., Hoogbergen, Maarten M., Garssen, Johan, and Verster, Joris C.
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COVID-19 pandemic ,WOUND healing ,MEDICAL care ,STAY-at-home orders ,PHARMACY students - Abstract
Background and Aims: The coronavirus disease‐2019 (COVID‐19) pandemic disrupted medical care of patients with chronic wounds, and in combination with other negative effects of lockdown measures, this may have a negative effect on mood and quality of life. Until now, the consequences of the COVID‐19 pandemic and associated lockdowns for individuals with impaired wound healing have not been investigated. Methods: An online survey was conducted to evaluate perceived immune fitness, mood, and health, both before and during the COVID‐19 pandemic. Results: Of the 331 Dutch pharmacy students that completed the survey, N = 42 participants reported slow healing wounds and/or wound infection and were allocated to the impaired wound healing group; the other N = 289 participants served as control group. The survey assessed mood, perceived immune fitness, and health correlates for (a) the year 2019 (the period before the lockdown), (b) the first lockdown period (March 15–May 11, 2020), (c) summer 2020 (no lockdown), and (d) the second lockdown (November 2020–April 2021). The analysis revealed that negative mood effects, reductions in quality of life, and perceived immune fitness during the two lockdowns were significantly more pronounced among individuals that reported impaired wound healing compared to the control group. The effects on mood, perceived immune fitness, and health correlates were most pronounced for the second lockdown period. Conclusion: The COVID‐19 pandemic is associated with significantly poorer mood, quality of life, and reduced perceived immune fitness. These effects are significantly more pronounced among individuals with self‐reported impaired wound healing. [ABSTRACT FROM AUTHOR]
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- 2022
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14. Pandemic Preparedness: The Importance of Adequate Immune Fitness.
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Kiani, Pantea, Balikji, Jessica, Kraneveld, Aletta D., Garssen, Johan, Bruce, Gillian, and Verster, Joris C.
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SARS-CoV-2 , *COVID-19 - Abstract
Pandemic preparedness is an important issue in relation to future pandemics. The two studies described here aimed to identify factors predicting the presence and severity of coronavirus disease 2019 (COVID-19) symptoms. The CLOFIT study comprised an online survey among the Dutch population (n = 1415). Perceived immune fitness before the pandemic (2019) and during the first lockdown period (15 March–11 May 2020) and the number and severity of COVID-19 symptoms were assessed. The COTEST study, conducted between December 2020 and June 2021, replicated the CLOFIT study in n = 925 participants who were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Dutch commercial test locations. The CLOFIT study revealed that immune fitness before the pandemic was the greatest predictor of the number and severity of COVID-19 symptoms (20.1% and 19.8%, respectively). Other significant predictors included immune fitness during the lockdown (5.5% and 7.1%, respectively), and having underlying diseases (0.4% and 0.5%, respectively). In the COTEST study, for those who tested positive for SARS-CoV-2, immune fitness before the pandemic was the single predictor of the number (27.2%) and severity (33.1%) of COVID-19 symptoms during the pandemic. In conclusion, for those who tested positive for SARS-CoV-2, immune fitness before the pandemic was the strongest predictor of the number and severity of COVID-19 symptoms during the pandemic. Therefore, the development of strategies to maintain an adequate immune fitness must be regarded as an essential component of pandemic preparedness. [ABSTRACT FROM AUTHOR]
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- 2022
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15. Mental Resilience, Mood, and Quality of Life in Young Adults with Self-Reported Impaired Wound Healing.
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Balikji, Jessica, Hoogbergen, Maarten M., Garssen, Johan, and Verster, Joris C.
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- 2022
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16. Inattention, Impulsivity, and Hyperactivity among Individuals with Self-Reported Impaired Wound Healing.
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Balikji J, Hoogbergen MM, Garssen J, and Verster JC
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Background: Inattention and impulsivity are common causes of accidents and injury. The aim of the current study was to examine the level of attention deficit (AD), hyperactivity, and impulsivity (HI) in individuals with and without self-reported impaired wound healing (IWH)., Methods: A survey was conducted among N = 773 Dutch young adults, 18-30 years old. N = 198 were allocated to the IWH group and N = 575 to the control group. All participants completed the Attention Deficit Hyperactivity Disorder (ADHD) Rating Scale., Results: The analysis revealed that the IWH group has significantly higher scores on AD and HI, compared to the control group. Among the IWH group, 12.8% screened positive for AD (compared to 5.8% of the control group) and 14.0% screened positive for HI (compared to 7.4% of the control group)., Conclusion: Clinically relevant increased inattention, impulsivity, and hyperactivity were observed among individuals with self-reported impaired wound healing.
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- 2022
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17. Self-Reported Impaired Wound Healing in Young Adults and Their Susceptibility to Experiencing Immune-Related Complaints.
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Balikji J, Hoogbergen MM, Garssen J, and Verster JC
- Abstract
The current study examined to what extent individuals with wound infection (WI group), slow healing wounds (SHW group), or both (COMBI group) report poorer immune fitness and whether they experience immune-related complaints more often as compared to healthy participants (control group). Survey data from 3613 Dutch students was re-analyzed. Compared to the control group, perceived immune fitness was significantly lower by the SHW group ( p < 0.001) and the COMBI group ( p < 0.001), but no difference was found for the WI group ( p = 0.059). Also, perceived immune fitness of the COMBI group was significantly worse compared to the WI group ( p = 0.040). Compared to the control group, reduced immune fitness was reported to be significantly more frequently by the SHW group ( p < 0.001) and the COMBI group ( p < 0.001). Reduced immune fitness was significantly more common for the COMBI group compared to the SHW group ( p = 0.011) and WI group ( p = 0.001). Immune-related complaints such as headache, runny nose, coughing, sore throat, diarrhea, flu, and fever were significantly more frequently reported by individuals with impaired wound healing. The effects were most pronounced in the COMBI group, followed by the SHW group and a lesser extent the WI group. A highly significant correlation was found between perceived immune fitness and the percentage of individuals that reported impaired wound healing. In conclusion, the findings confirm that poorer immune functioning is characteristic for individuals with impaired wound healing. In follow-up studies, immune biomarkers analyses are needed to support patient-reported outcome measures.
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- 2022
- Full Text
- View/download PDF
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