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Introduction: Skin adnexal tumours are relatively uncommon in routine practice. They pose a diagnostic challenge to pathologists, due to their overlapping features and multiple lines of differentiation. Morphological assessment is crucial to subtype these lesions accurately. Aim: To study skin adnexal tumours based on their histomorphology and clinical profile. Materials and Methods: This was a retrospective, descriptive study conducted from January 2016 to December 2019 on 52 cases, done at BGS Global Institute of Medical Sciences, Bengaluru, Karnataka, India. All benign and malignant skin adnexal tumours were included in the study. Microscopic findings were studied by two pathologists. Based on histomorphological analysis, tumours were classified as per recent World Health Organisation (WHO) guidelines. Results: A total of 52 cases were studied. Of the 52 cases, 45 (87%) cases were benign and 7 (13%) cases were malignant. The most common benign adnexal tumour was Pilomatricoma and the most common malignant tumour was Sebaceous Carcinoma. The most common site of presentation was the head and neck, followed by lower limb and trunk. Conclusion: Skin adnexal tumours are subtyped based on the predominant morphological component. Benign adnexal tumours are more common compared to malignant adnexal tumours. Histopathological assessment is the mainstay in evaluating skin adnexal tumours.

Introduction: Papulosquamous skin lesions are characterised by a unique morphologic feature called as superficial cutaneous reactive unit with the basic patterns of predominantly lichenoid and psoriasiform dermatitis. It constitutes largest conglomerate of skin diseases posing diagnostic dilemma to both dermatologist and pathologist. Although characterised by typical scaly papules, a lot of similarity in both clinical presentation and distribution of papulosquamous skin disorders makes clinical diagnosis more difficult. The diagnostic specificity with overlapping features will be achieved by correlating the gold standard histopathological findings with clinical details. Aim: To study the morphological patterns of non-infectious erythematous papulosquamous lesions of skin with clinical diagnosis. Materials and Methods: This was a cross-sectional observational study in all the prediagnosed cases of noninfectious erythematous papulosquamous lesions by the dermatologist in BGS Global Institute of Medical Sciences, Bengaluru from July 2016 to December 2018. Demographic profiles including the clinical and histopathological details were reviewed by consensus opinion by the pathologists. The results were tabulated and analysed using SPSS 22 software version. Results: Out of 90 cases of papulosquamous lesion, lichenoid pattern of reaction 51 (56.66%) was commonest followed by psoriasiform pattern of reaction 39 cases (43.34%). Lichen planus 34 cases (37.8%) was the common diagnosis among the lichenoid pattern of lesion followed by psoriasis 27 cases (30.1%) in psoriasiform pattern of lesions. Histopathological features commonly seen were hyperkeratosis and parakeratosis in both lichen planus and psoriasis. Positive clinicopathological correlation was highest in lichen planus and psoriasis. Conclusion: A broader morphological spectrum of papulosquamous lesions exist. The combined clinical approach with histopathological findings helps in accurate diagnosis of papulosquamous lesions.

Introduction: A variety of disorders affect the upper gastrointestinal tract. Study of endoscopic biopsies is imperative to make an accurate diagnosis, which will aid in early diagnosis and appropriate management of the patient. Aim: To determine the histomorphological spectrum and the occurrence of upper gastrointestinal lesions; and also to associate endoscopic diagnosis with histopathology. Materials and Methods: This was a retrospective, descriptive study conducted from May 2017 to April 2019 on 106 cases, done at BGS Global Institute of Medical Sciences, Bengaluru, Karnataka, India. Microscopic findings were studied by two pathologists. Results: A total of 106 cases were studied. Majority of the patients (56%) presented with abdominal pain followed by dyspepsia and dysphagia. Stomach was the most common site of biopsy followed by oesophagus and duodenum. Majority of oesophageal and gastric biopsies were found to be neoplastic i.e., 70.8% and 56.3% respectively; however, non-neoplastic lesions formed the majority in duodenal biopsies (88.9%). The most common malignancy was squamous cell carcinoma, which occurred predominantly in the middle third of the oesophagus. The most common malignancy in the stomach was adenocarcinoma. Correlation between endoscopic diagnosis and histopathology was done in 70 cases; and there was consensus in 78.5% of the cases (55/70 cases). Conclusion: Endoscopy with assisted biopsy is the gold standard for diagnosis of upper gastrointestinal disorders. An interdisciplinary approach towards diagnosis and treatment involving the pathologist and clinician is important.

Primary fallopian tube carcinoma is considered one of the rarest female genital cancers, and its bilateral occurrence is even rarer. Because of the rarity of fallopian tube carcinomas as well as the clinical presentation which simulates an ovarian cancer, a correct preoperative diagnosis of fallopian tube carcinoma is seen only in 4% of cases, and is usually first appreciated by Pathologists. We are reporting our experience of a case of bilateral primary serous carcinoma of the fallopian tube in a 36-year-old female.