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14 results on '"Brusadelli, Claudia"'

2. High-risk HPV-positive and -negative high-grade cervical dysplasia: Analysis of 5-year outcomes

Author

Bogani, Giorgio, Sopracordevole, Francesco, Di Donato, Violante, Ciavattini, Andrea, Ghelardi, Alessandro, Lopez, Salvatore, Simoncini, Tommaso, Plotti, Francesco, Casarin, Jvan, Serati, Maurizio, Pinelli, Ciro, Valenti, Gaetano, Bergamini, Alice, Gardella, Barbara, Dell'acqua, Andrea, Monti, Ermelinda, Vercellini, Paolo, Fischetti, Margherita, D'ippolito, Giovanni, Aguzzoli, Lorenzo, Mandato, Vincenzo D., Carunchio, Paola, Carlinfante, Gabriele, Giannella, Luca, Scaffa, Cono, Falcone, Francesca, Borghi, Chiara, Ditto, Antonino, Malzoni, Mario, Giannini, Andrea, Salerno, Maria Giovanna, Liberale, Viola, Contino, Biagio, Donfrancesco, Cristina, Desiato, Michele, Perrone, Anna Myriam, Dondi, Giulia, De Iaco, Pierandrea, Chiappa, Valentina, Ferrero, Simone, Sarpietro, Giuseppe, Matarazzo, Maria G., Cianci, Antonio, Bosio, Sara, Ruisi, Simona, Guerrisi, Rocco, Brusadelli, Claudia, Mosca, Lavinia, Lagana’, Antonio Simone, Tinelli, Raffaele, Signorelli, Mauro, De Vincenzo, Rosa, Zannoni, Gian Franco, Ferrandina, Gabriella, Lovati, Sara, Petrillo, Marco, Dessole, Salvatore, Carlea, Annunziata, Zullo, Fulvio, Angioli, Roberto, Greggi, Stefano, Spinillo, Arsenio, Ghezzi, Fabio, Colacurci, Nicola, Muzii, Ludovico, Benedetti Panici, Pierluigi, Scambia, Giovanni, and Raspagliesi, Francesco

Published
2021
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3. Sentinel node mapping vs. sentinel node mapping plus back-up lymphadenectomy in high-risk endometrial cancer patients: Results from a multi-institutional study

Author

Bogani, Giorgio, Papadia, Andrea, Buda, Alessandro, Casarin, Jvan, Di Donato, Violante, Gasparri, Maria Luisa, Plotti, Francesco, Pinelli, Ciro, Paderno, Maria Chiara, Lopez, Salvatore, Perrone, Anna Myriam, Barra, Fabio, Guerrisi, Rocco, Brusadelli, Claudia, Cromi, Antonella, Ferrari, Debora, Chiapp, Valentina, Signorelli, Mauro, Leone Roberti Maggiore, Umberto, Ditto, Antonino, Palaia, Innocenza, Ferrero, Simone, De Iaco, Pierandrea, Angioli, Roberto, Panici, Pierluigi Benedetti, Ghezzi, Fabio, Landoni, Fabio, Mueller, Michael D., and Raspagliesi, Francesco

Published
2021
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4. Spotlight on the role of human papillomavirus vaccines

Author

Bogani, Giorgio, Raspagliesi, Francesco, di Donato, Violante, Brusadelli, Claudia, Guerrisi, Rocco, Pinelli, Ciro, Casarin, Jvan, Ghezzi, Fabio, Del Fabro, Anna, Ditto, Antonino, Simoncini, Tommaso, Ciavattini, Andrea, and Sopracordevole, Francesco

Published
2021
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5. Recurrence rate after loop electrosurgical excision procedure (LEEP) and laser Conization: A 5-year follow-up study

Author

BOGANI, Giorgio, DI DONATO, Violante, SOPRACORDEVOLE, Francesco, CIAVATTINI, Andrea, GHELARDI, Alessandro, LOPEZ, Salvatore, SIMONCINI, Tommaso, PLOTTI, Francesco, CASARIN, Jvan, SERATI, Maurizio, PINELLI, Ciro, VALENTI, Gaetano, BERGAMINI, Alice, GARDELLA, Barbara, DELL'ACQUA, Andrea, MONTI, Ermelinda, VERCELLINI, Paolo, FISCHETTI, Margherita, D'IPPOLITO, Giovanni, AGUZZOLI, Lorenzo, MANDATO, Vincenzo D., CARUNCHIO, Paola, CARLINFANTE, Gabriele, GIANNELLA, Luca, SCAFFA, Cono, FALCONE, Francesca, BORGHI, Chiara, DITTO, Antonino, MALZONI, Mario, GIANNINI, Andrea, SALERNO, Maria Giovanna, LIBERALE, Viola, CONTINO, Biagio, DONFRANCESCO, Cristina, DESIATO, Michele, PERRONE, Anna Myriam, DONDI, Giulia, De IACO, Pierandrea, LEONE ROBERTI MAGGIORE, Umberto, SIGNORELLI, Mauro, CHIAPPA, Valentina, FERRERO, Simone, SARPIETRO, Giuseppe, MATARAZZO, Maria G., CIANCI, Antonio, BOSIO, Sara, RUISI, Simona, GUERRISI, Rocco, BRUSADELLI, Claudia, MOSCA, Lavinia, TINELLI, Raffaele, DE VINCENZO, Rosa, ZANNONI, Gian Franco, FERRANDINA, Gabriella, PETRILLO, Marco, DESSOLE, Salvatore, ANGIOLI, Roberto, GREGGI, Stefano, SPINILLO, Arsenio, GHEZZI, Fabio, COLACURCI, Nicola, MUZII, Ludovico, BENEDETTI PANICI, Pierluigi, SCAMBIA, Giovanni, and RASPAGLIESI, Francesco

Published
2020
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8. Survival outcomes in endometrial cancer patients having lymphadenectomy, sentinel node mapping followed by lymphadectomy and sentinel node mapping alone: Long-term results of a propensity-matched analysis

Author

Bogani, Giorgio, Casarin, Jvan, Leone Roberti Maggiore, Umberto, Ditto, Antonino, Pinelli, Ciro, Dell'acqua, Andrea, Lopez, Salvatore, Chiappa, Valentina, Brusadelli, Claudia, Guerrisi, Rocco, Ferrero, Simone, Ghezzi, Fabio, and Raspagliesi, Francesco

Published
2020
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10. Gynecologic oncology at the time of COVID-19 outbreak.

Author

Bogani, Giorgio, Brusadelli, Claudia, Guerrisi, Rocco, Lopez, Salvatore, Signorelli, Mauro, Ditto, Antonino, and Raspagliesi, Francesco

Subjects
*COVID-19 pandemic, *COVID-19, *GYNECOLOGIC oncology, *SARS-CoV-2, *GYNECOLOGIC care, VAGINAL surgery
Abstract

The World Health Organization (WHO) classified the novel coronavirus (i.e., coronavirus disease 2019 [COVID-19]) as a global public health emergency. COVID-19 threatens to curtail patient access to evidence-based treatment. Medicine is changing, basically due to the limited available resources. In the field of gynecologic oncology, we have to re-design our treatments' paradigm. During COVID-19 pandemic outbreak, the highest priority is to achieve the maximum benefit from less demanding procedures. Extensive procedures should be avoided, in order to reduce hospitalization and postoperative events that might increase the in-hospital spread of the virus. There are ongoing concerns on the use of laparoscopic procedures, related to the possible contamination of the staff working in the operation room. Other minimally invasive techniques, including, vaginal surgery as well as robotic-assisted and isobaric procedures would be preferred over laparoscopy. A fair allocation of resources is paramount adequate treatments. [ABSTRACT FROM AUTHOR]

Published
2020
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12. Neurological Manifestations of COVID-19 in Children: A Case of Facial Nerve Palsy.

Author

Decio, Alice, Mazza, Angelo, Quadri, Vera, Ronconi, Monica Silvia, Brusadelli, Claudia, Ruggeri, Maurizio, and D'Antiga, Lorenzo

Subjects
*NEUROLOGIC manifestations of general diseases, *FACIAL nerve, *COVID-19, *FACIAL paralysis, *COVID-19 pandemic, *FACIAL nerve diseases
Abstract

Kaur and colleagues[1] presented a child with an unusual neurological presentation (longitudinally extensive transverse myelitis) following SARS-CoV-2 infection. Unlike acute presentations due to direct SARS-CoV-2 invasion of the central nervous system (i.e. encephalitis[2]), immune-mediated neurological symptoms may occur when the patient has already cleared the virus and has developed antibodies against it. Along with other well-established infections that trigger facial nerve palsy, we propose to carry out both SARS-CoV-2 swab and serology testing because facila palsy could represent an immune-mediated neurological complication of COVID-19, similar to transverse myelitis and Guillain-Barrè syndrome. [Extracted from the article]

Published
2021
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13. The impact of HPV-specific infection in women diagnosed with atypical glandular cells: Results from the HPV-AGC study.

Author

Bogani, Giorgio, Sopracordevole, Francesco, Casarin, Jvan, Pinelli, Ciro, Leone Roberti Maggiore, Umberto, Brusadelli, Claudia, Guerrisi, Rocco, Ditto, Antonino, Dell'Acqua, Andrea, Serati, Maurizio, Lopez, Salvatore, Ferrero, Simone, Ghezzi, Fabio, and Raspagliesi, Francesco

Subjects
*PAPILLOMAVIRUS diseases, *CERVICAL cancer, *ENDOMETRIUM, *ENDOMETRIAL hyperplasia, *CERVIX uteri, *PAP test, *ENDOMETRIAL cancer
Abstract

To evaluate the impact of various HPV types on the risk of developing lesions of the uterus (either uterine cervix and endometrium) in women diagnosed with "atypical glandular cells" (AGC) at Pap smear. This is a multi-institutional retrospective study. Data of women diagnosed with AGC were retrospectively reviewed. All patients included had data about HPV DNA testing and 1-year clinical follow-up. Overall, chart of 480 patients were evaluated. After the exclusion of 286 patients, data of 194 patients were available for the analysis. Mean age was 43.9 (±6.0) years. HPV infection was documented in 136 women (70.1 %). Among HPV positive patients the risk of having/developing a lesion was 33.8 % (n = 46). Lesions included low- (L-SIL) and high- (H-SIL) squamous intraepithelial lesions, in situ adenocarcinoma of the uterine cervix, invasive cancer of the uterine cervix, endometrial hyperplasia and endometrial cancer in 16 (11.7 %), 18 (13.2 %), 6 (4.4 %), 3 (2.2 %), 2 (1.5 %) and 1 (1%), respectively. Among HPV negative patients the risk of having/developing a lesion was 15.5 %. They included l -SIL, H-SIL, in situ adenocarcinoma, endometrial hyperplasia and endometrial cancer in 1 (1.7 %), 1 (1.7 %), 1 (1.7 %), 3 (5.1 %) and 3 (5.1 %), respectively. Patients diagnosed with HPV16 were at higher risk of having/developing cervical lesions in comparison to patients with other HPV infections (p < 0.01). In comparison to other HPV types, the presence of HPV 18, 31, 33, and 45 did not increase the risk of developing a lesion over the time (p > 0.2). HPV positive patients were at higher risk of being diagnosed with a cervical lesion within 6 months from detection of AGC. Patients diagnosed with AGC are at risk to have / developing cervical and uterine lesions. Further prospective evidence is needed. [ABSTRACT FROM AUTHOR]

Published
2020
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14. Assessing the Long-Term Role of Vaccination against HPV after Loop Electrosurgical Excision Procedure (LEEP): A Propensity-Score Matched Comparison.

Author

Bogani G, Raspagliesi F, Sopracordevole F, Ciavattini A, Ghelardi A, Simoncini T, Petrillo M, Plotti F, Lopez S, Casarin J, Serati M, Pinelli C, Valenti G, Bergamini A, Gardella B, Dell'Acqua A, Monti E, Vercellini P, D'ippolito G, Aguzzoli L, Mandato VD, Carunchio P, Carlifante G, Gianella L, Scaffa C, Falcone F, Ferla S, Borghi C, Ditto A, Malzoni M, Giannini A, Salerno MG, Liberale V, Contino B, Donfrancesco C, Desiato M, Perrone AM, Dondi G, De Iaco P, Leone Roberti Maggiore U, Signorelli M, Chiappa V, Ferrero S, Sarpietro G, Matarazzo MG, Cianci A, Bocio S, Ruisi S, Guerrisi R, Brusadelli C, Mosca L, Tinelli R, De Vincenzo R, Zannoni GF, Ferrandina G, Dessole S, Angioli R, Greggi S, Spinillo A, Ghezzi F, Colacurci N, Fischetti M, Carlea A, Zullo F, Muzii L, Scambia G, Benedetti Panici P, and Di Donato V

Abstract

Background : Primary prevention through vaccination is a prophylactic approach aiming to reduce the risk of developing human papillomavirus (HPV)-related lesions. No mature and long-term data supported the adoption of vaccination in women undergoing conization. Methods: This is a retrospective multi-institutional study. Charts of consecutive patients undergoing conization between 2010 and 2014 were collected. All patients included had at least 5 years of follow-up. We compared outcomes of patients undergoing conization plus vaccination and conization alone. A propensity-score matching algorithm was applied in order to reduce allocation biases. The risk of developing recurrence was estimated using Kaplan-Meir and Cox hazard models. Results : Overall, charts of 1914 women were analyzed. The study group included 116 (6.1%) and 1798 (93.9%) women undergoing conization plus vaccination and conization alone, respectively. Five-year recurrence rate was 1.7% ( n = 2) and 5.7% ( n = 102) after conization plus vaccination and conization alone, respectively ( p = 0.068). After the application of a propensity-score matching, we selected 100 patients undergoing conization plus vaccination and 200 patients undergoing conization alone. The crude number of recurrences was 2 (2%) and 11 (5.5%) for patients undergoing conization plus vaccination and conization alone, respectively ( p = 0.231). Vaccination had no impact on persistent lesions (no negative examination between conization and new cervical dysplasia; p = 0.603), but reduced the risk of recurrent disease (patients who had at least one negative examination between conization and the diagnosis of recurrent cervical dysplasia; p = 0.031). Conclusions: Patients having vaccination experience a slightly lower risk of recurrence than women who had not, although not statistically significantly different. Further evidence is needed to assess the cost effectiveness of adopting vaccination in this setting.

Published
2020
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