760 results on '"Cabrales, Pedro"'
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2. Toxic side-effects of diaspirin cross-linked human hemoglobin are attenuated by the apohemoglobin-haptoglobin complex
3. A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data
4. A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation
5. Hypoxically stored RBC resuscitation in a rat model of traumatic brain injury and severe hemorrhagic shock
6. Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues
7. Changes in oxygen delivery during experimental models of cerebral malaria
8. Polymerized human hemoglobin with low and high oxygen affinity in trauma models
9. Prony Analysis of Left Ventricle Pressure and Volume
10. Apohemoglobin-haptoglobin complex alleviates iron toxicity in mice with β-thalassemia via scavenging of cell-free hemoglobin and heme
11. Implications of microvascular dysfunction and nitric oxide mediated inflammation in severe COVID-19 infection
12. Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock
13. Abstract 10336: Phase 3 Anticancer Agent, RRx-001, Ameliorates Hypoxia-Induced Pulmonary Hypertension
14. Negative pressure increases microvascular perfusion during severe hemorrhagic shock
15. The Disconnect Between Extracorporeal Circulation and the Microcirculation: A Review
16. A Review on Microvascular Hemodynamics: The Control of Blood Flow Distribution and Tissue Oxygenation
17. Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury
18. Resuscitation from hemorrhagic shock after traumatic brain injury with polymerized hemoglobin
19. Polymerized albumin restores impaired hemodynamics in endotoxemia and polymicrobial sepsis
20. CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice
21. Quantitative analysis of spatial irregularities in RBCs flows
22. High-molecular-weight linear polymers improve microvascular perfusion after extracorporeal circulation.
23. Navigating the “No Man's Land” of TKI-Failed EGFR-Mutated Non–Small Cell Lung Cancer (NSCLC): A Review
24. Resuscitation from Hemorrhagic Shock With Fresh and Stored Blood and Polymerized Hemoglobin
25. RRx-001 protects normal tissues but not tumors via Nrf2 induction and Bcl-2 inhibition
26. Knockdown of ANT2 reduces adipocyte hypoxia and improves insulin resistance in obesity
27. Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues
28. Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice
29. Polymerized human hemoglobin facilitated modulation of tumor oxygenation is dependent on tumor oxygenation status and oxygen affinity of the hemoglobin-based oxygen carrier
30. The Molecular Size of Bioengineered Oxygen Carriers Determines Tissue Oxygenation in a Hypercholesterolemia Guinea Pig Model of Hemorrhagic Shock and Resuscitation.
31. Response by Lundberg et al to Letter Regarding Article, “Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell”
32. Transfusion of Anaerobically or Conventionally Stored Blood After Hemorrhagic Shock
33. Inflammatory response to implantation of transparent nanocrystalline yttria-stabilized zirconia using a dorsal window chamber model
34. Cardiac-specific knockout and pharmacological inhibition of Endothelin receptor type B lead to cardiac resistance to extreme hypoxia
35. Poly(ethylene glycol) hydrogels with cell cleavable groups for autonomous cell delivery
36. Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell
37. Data Management 101 for drug developers: A peek behind the curtain.
38. GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model.
39. Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study
40. RRx-001 protects against cisplatin-induced toxicities
41. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice
42. Topically Applied NO‐Releasing Nanoparticles Can Increase Intracorporal Pressure and Elicit Spontaneous Erections in a Rat Model of Radical Prostatectomy
43. Abstract 16070: Cardiomyocyte-Specific Endothelin Receptor Type B Knockout Mice Confers Cardiac Resistance to Extreme Hypoxia
44. The Double-Edged Sword of Erythrocytes in Health and Disease via Their Adhesiveness.
45. RRx-001: a chimeric triple action NLRP3 inhibitor, Nrf2 inducer, and nitric oxide superagonist.
46. Targeting tumor hypoxia with the epigenetic anticancer agent, RRx-001: a superagonist of nitric oxide generation
47. A look inside the mechanistic black box: Are red blood cells the critical effectors of RRx-001 cytotoxicity?
48. RRx-001, A novel dinitroazetidine radiosensitizer
49. Oxygen delivery during extreme anemia with ultra-pure earthworm hemoglobin
50. Phase 1 pilot study of RRx-001 + nivolumab in patients with advanced metastatic cancer (PRIMETIME).
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