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40 results on '"Cavalli-Sforza, L.L."'

2. Peopling of three Mediterranean islands (Corsica, Sardinia, and Sicily) inferred by Y-chromosome biallelic variability

Author

Francalacci, P., Morelli, L., Underhill, P.A., Lillie, A.S., Passarino, G., Useli, A., Madeddu, R., Paoli, G., Tofanelli, S., Calo, C.M., Ghiani, M.E., Varesi, L., Memmi, M., Vona, G., Lin, A.A., Oefner, P., and Cavalli-Sforza, L.L.

Subjects
Corsica -- Natural history, Sardinia -- Natural history, Sicily -- Natural history, Population geography -- Research, Population genetics -- Research, Y chromosome -- Physiological aspects, Anthropology/archeology/folklore
Abstract

An informative set of biallelic polymorphisms was used to study the structure of Y-chromosome variability in a sample from the Mediterranean islands of Corsica and Sicily, and compared with data on Sardinia to gain insights into the ethnogenesis of these island populations. The results were interpreted in a broader Mediterranean context by including in the analysis neighboring populations previously studied with the same methodology. All samples studied were enclosed in the comparable spectrum of European Y-chromosome variability. Pronounced differences were observed between the islands as well as in the percentages of haplotypes previously shown to have distinctive patterns of continental phylogeography. Approximately 60% of the Sicilian haplotypes are also prevalent in Southern Italy and Greece. Conversely, the Corsican sample had elevated levels of alternative haplotypes common in Northern Italy. Sardinia showed a haplotype ratio similar to that observed in Corsica, but with a remarkable difference in the presence of a lineage defined by marker M26, which approaches 35% in Sardinia but seems absent in Corsica. Although geographically adjacent, the data suggest different colonization histories and a minimal amount of recent gene flow between them. Our results identify possible ancestral continental sources of the various island populations and underscore the influence of founder effect and genetic drill The Y-chromosome data are consistent with comparable mtDNA data at the RFLP haplogroup level of resolution, as well as linguistic and historic knowledge. KEY WORDS Y-chromosome; population genetics; Mediterranean populations

Published
2003

36. Male/female ratio in centenarians: a possible role played by population genetic structure

Author

Passarino, G., Calignano, C., Vallone, A., Franceschi, C., Jeune, B., Robine, J.M., Yashin, A.I., Cavalli Sforza, L.L., and De Benedictis, G.

Subjects
*CENTENARIANS, *STATISTICS
Abstract

All the demographic surveys on the centenarians have highlighted that females outnumber males. The centenarians'' male/female (M/F) ratio reported by most studies ranges between 1:4 and 1:7. A puzzling 1:2 ratio was observed in Calabria, a Southern Italian region. To our knowledge only in Sardinia a similar phenomenon had been previously observed. We have therefore used the data of the Italian Institute of Statistics to figure out the centenarians'' M/F ratio in the Italian regions. We found that this ratio gradually decreases from South to North. Such a result is certainly due to many factors. Thus, we have explored the possibility, it is also influenced by the genetic structure of the Italian population. In fact, the distribution of the centenarians'' M/F ratio turned out to be significantly correlated with the genetic structure of the Italian population as outlined by the principal component analysis. [Copyright &y& Elsevier]

Published
2002
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