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4 results on '"Chady Atallah"'

1. Surgical and local control outcomes after sequential short-course radiation therapy and chemotherapy for rectal cancer

Author

I-Chia Liu, MD, Susan Gearhart, MD MEd, Suqi Ke, MS, Chen Hu, PhD MS, Haniee Chung, MD, Jonathan Efron, MD, Alodia Gabre-Kidan, MD MPH, Peter Najjar, MD MBA, Chady Atallah, MD, Bashar Safar, MD, Eric S. Christenson, MD, Nilofer S. Azad, MD, Valerie Lee, MD, Atif Zaheer, MD, Jacqueline E. Birkness-Gartman, MD, Abhinav V. Reddy, MD, Amol K. Narang, MD, and Jeffrey Meyer, MD MS

Subjects
Rectal cancer, Radiation therapy, Proctectomy, Surgery, RD1-811
Abstract

Background: Total neoadjuvant therapy (TNT) is an accepted approach for the management of locally advanced rectal cancer (LARC) and is associated with a decreased risk of development of metastatic disease compared to standard neoadjuvant therapy. However, questions remain regarding surgical outcomes and local control in patients who proceed to surgery, particularly when radiation is given first in the neoadjuvant sequence. We report on our institution's experience with patients who underwent short-course radiation therapy, consolidation chemotherapy, and surgery. Methods: We retrospectively reviewed surgical specimen outcomes, postoperative complications, and local/pelvic control in a large cohort of patients with LARC who underwent neoadjuvant therapy incorporating upfront short-course radiation therapy followed by consolidation chemotherapy. Results: In our cohort of 83 patients who proceeded to surgery, a complete/near-complete mesorectal specimen was achieved in 90 % of patients. This outcome was not associated with the time interval from completion of radiation to surgery. Postoperative complications were acceptably low. Local control at two years was 93.4 % for all patients- 97.6 % for those with low-risk disease and 90.4 % for high-risk disease. Conclusion: Upfront short-course radiation therapy and consolidation chemotherapy is an effective treatment course. Extended interval from completion of short-course radiation therapy did not impact surgical specimen quality.

Published
2024
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2. Tubo-ovarian abscess: A potential mimicker of urachal malignancy

Author

Sajya M. Singh, James L. Liu, Farzad Sedaghat, Stephanie L. Wethington, Chady Atallah, and Max Kates

Subjects
Urachal malignancy, Tubo-ovarian abscess, Pelvic inflammatory disease, Pregnancy, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Urachal cancer is a rare but aggressive malignancy. A urachal mass concerning for adenocarcinoma was identified in a 32-year-old G2P1 female on 12-week ultrasound and confirmed on pelvic MRI. Due to progressive growth of the mass and refractory abdominal pain, a multi-disciplinary meeting was held, after which the patient chose to undergo an exploratory laparotomy. A tubo-ovarian abscess was identified involving the intestine, right ovary, fallopian tube, and communicating with a patent, necrotic urachus. This is the first reported case of a tubo-ovarian abscess masquerading as a urachal malignancy, which can present similarly with abdominal pain and irritative urinary symptoms.

Published
2022
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3. High-resolution anoscopy, is there a benefit in proceeding directly to the operating room?

Author

E. Paredes, Beat Moeckli, N. Cowell, A. Najafian, S. Carbunaru, A. Chudnovets, Sandy H. Fang, Chady Atallah, and Joseph K. Canner

Subjects
Operating Rooms, medicine.medical_specialty, Anal Canal, 030312 virology, Proctoscopy, 03 medical and health sciences, 0302 clinical medicine, High-grade dysplasia, Humans, Medicine, Anal cancer, Prospective Studies, Anal pap smear, 0303 health sciences, medicine.diagnostic_test, ddc:617, business.industry, Anal Pap Smear, Gastroenterology, Anoscopy, Anal dysplasia, Anus Neoplasms, medicine.disease, Institutional review board, Colorectal surgery, High-resolution anoscopy, Patient comfort, Dysplasia, 030220 oncology & carcinogenesis, Original Article, Surgery, Radiology, business, Abdominal surgery
Abstract

Background The development of high-resolution anoscopy (HRA) has advanced our ability to detect anal dysplasia. Historically, HRA is performed in a clinical setting and subsequent ablation is performed in the clinical setting or operating room. The aim of this study was to determine the most effective venue for the performance of HRA. Methods Following institutional review board (IRB) approval, the correlation between anal cytology and HRA performed in the clinic versus in the operating room was evaluated. Data were extracted from our IRB-approved prospective HRA database over the time period of 2013–2017. Results One hundred twenty-eight HRAs were compared (101 in the clinical setting, 27 in the operating room). There was a statistically significant difference in the correlation between anal cytology and HRA pathology for procedures performed in the clinical setting (55% [56/101]) versus those performed in the operating room (82% [22/27]) (p = 0.014). More biopsies were obtained in the operating room than in the clinic setting (3 vs. 1, p Conclusions Detection rates for anal dysplasia on HRA, are significantly higher when performed in the operating room. To prevent discomfort in the clinical setting, patients with high-grade dysplasia on anal pap testing may benefit from proceeding directly to the operating room for concurrent HRA and ablation.

Published
2021

4. Accuracy of clinical fetal weight estimation by Midwives

Author

Ramzi AbouJaoude, Elie Attieh, Norma Assaf, Chady Atallah, Hanaa Khaled, and Assaad Kesrouani

Subjects
Adult, medicine.medical_specialty, Birth weight, 030231 tropical medicine, Statistics as Topic, Gestational Age, Midwifery, 03 medical and health sciences, Clinical, 0302 clinical medicine, Pregnancy, Obstetrics and Gynaecology, medicine, Rupture of membranes, Birth Weight, Humans, Prospective Studies, Prospective cohort study, Gynecology, Fetus, 030219 obstetrics & reproductive medicine, business.industry, Midwife, Infant, Newborn, Obstetrics and Gynecology, Gestational age, medicine.disease, Fetal weight, Obstetrics, Cohort, Female, Clinical Competence, medicine.symptom, business, Weight gain, Estimation, Research Article
Abstract

Background Clinical fetal weight estimation is a common practice in obstetrics. This study aims to evaluate the accuracy of fetal weight estimation by midwives, and to identify factors that may lead to overestimation or underestimation of fetal weight. Methods A cohort prospective study in a Lebanese university hospital, included weight estimation of singleton pregnancies above 35 weeks. Multiple pregnancies, unclear dating, growth retardation, malformations and stillbirths cases are excluded. The estimated fetal weight is recorded by midwives in a sealed envelope and compared to true weight later. The effects of BMI, weight gain, parity, diabetes, hypertension, neonate’s sex and weight, uterine contractions, rupture of membranes and daytime or nighttime shift on these estimations were assessed. Results One hundred and sixty-six patients were included. Mean birth weight was 3246 ± 362 g. Mean absolute percentage error of weight estimation was 8.5 ± 6.7% (0–30.9%). Estimation was within the correct range of ±10% in 63% of cases. Maternal and fetal factors did not significantly change weight estimation. Fetuses with birth weights more than 4000 tended to be underestimated by midwives. Estimation improved over time (nonsignificant). Conclusions Maternal and fetal factors, except for macrosomia, have limited impact on estimation of fetal birth weight. Macrosomia is challenging because of a consistent tendency of underestimation by midwives.

Published
2017

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