58 results on '"Cruz-Correia R"'
Search Results
2. Proceedings of the 26th IEEE International Symposium on Computer-Based Medical Systems (CBMS'13, Porto, Portugal, June 20-22, 2013)
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Pereira Rodrigues, P., Pechenizkiy, M., Gama, J., Cruz-Correia, R., Liu, Jiming, Traina, A.J.M., Lucas, P.J.F., Soda, P., and Data Mining
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- 2013
3. OpenEHR aware multi agent system for interinstitutional health data integration.
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Vieira-Marques, P., Bacelar-Silva, G., Patriarca-Almeida, J., Robles, S., Frade, S., and Cruz-Correia, R.
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ELECTRONIC health records ,MEDICAL care ,MEDICAL records ,INTERNETWORKING ,COMPUTER software - Abstract
Most patients receive care from many health care providers, and consequently their health data is dispersed over many institutions' paper and EHR-based record systems. This reality leads to a fragmented system of storing and retrieving essential patient data that impedes optimal care leading to the coexistence of somewhat autistic systems. Providing means for scattered clinical information to be congregated where and when needed may have a strong impact on healthcare quality. Interoperability is a major requisite for effectively sharing information between systems. Standards like openEHR play an important role on achieving interoperability. Agents are software entities, which can embody different perspectives of the surrounding environment and act accordingly. They can perceive the dynamic character of the environment and update their knowledge, enabling pro-activeness regarding actions that are better suited according to a particular user and a given set of goals. In this work we extend our previous work of building a VEPR for inter-institutional data integration with the inclusion of openEHR usage for querying and storing data in order to pursuit the efforts towards Health Information Systems semantic interoperability. [ABSTRACT FROM AUTHOR]
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- 2014
4. OpenEHR aware multi agent system for inter-institutional health data integration.
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Vieira-Marques, P., Patriarca-Almeida, J., Frade, S., Bacelar-Silva, G., Robles, S., and Cruz-Correia, R.
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- 2014
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5. Implementation of medical algorithms in the Breast Pathology module of VCIntegrator.
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Trindade-Vilaca, C., Silva-Costa, T., and Cruz-Correia, R.
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- 2011
6. Usability of authentication and access control: A case study in healthcare.
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Ferreira, A., Cruz-Correia, R., and Antunes, L.
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- 2011
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7. Improving the implementation of access control in EMR.
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Ferreira, A., Cruz-Correia, R., Chadwick, D., and Antunes, L.
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- 2008
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8. How to Break Access Control in a Controlled Manner.
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Ferreira, A., Cruz-Correia, R., Antunes, L., Farinha, P., Oliveira-Palhares, E., Chadwick, D.W., and Costa-Pereira, A.
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- 2006
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9. Promoting spontaneous adverse drug reaction reporting in hospitals using a hyperlink to the online reporting form: an ecological study in Portugal.
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Ribeiro-Vaz I, Santos C, da Costa-Pereira A, Cruz-Correia R, Ribeiro-Vaz, Inês, Santos, Cristina, da Costa-Pereira, Altamiro, and Cruz-Correia, Ricardo
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Background: Spontaneous adverse drug reaction (ADR) reporting has been described as an efficient method to detect drug safety signals. However, under-reporting is a major issue undermining the effectiveness of spontaneous reports. Among hospitalized patients, ADRs are a particularly serious problem because these patients are often treated with more than one drug, and these drugs are often new and aggressive.Objective: To promote spontaneous ADR reporting by healthcare professionals working in hospitals in the northern regions of Portugal, we propose the inclusion of a hyperlink to an online ADR reporting form on hospitals' electronic patient records (EPRs). The main aim of this study was to evaluate the impact of these hyperlinks on the number of spontaneous ADR reports to the Northern Pharmacovigilance Centre (UFN - Unidade de Farmacovigilância do Norte). We also assess the number of daily UFN website visits before and after the inclusion of the hyperlinks.Methods: An ecological study was performed in northern Portuguese hospitals from 2006 to 2010. The hyperlinks were included in either EPRs or on computer desktops. The median of spontaneous ADR reports (total and online) per month and the respective ranges were presented before and after the intervention in all hospitals in this study. The comparisons were performed using the Mann-Whitney U-test.Results: Sixteen hospital centres were involved in the study (27 hospitals). Eleven centres (18 hospitals) included the hyperlinks. Considering the hospitals with hyperlink access to the EPRs, the median ADR reports per month significantly increased, from two (range 0-12) to five reports (range 1-17). The median of ADR reports per month using the online form also increased significantly, from one (range 0-5) before the intervention to four (range 1-17) after it. Moreover, serious ADRs increased 3-fold, and non-previously described ADRs increased 4.5-fold. None of these significant increases were observed in the hospitals where the hyperlink was not installed. We also found a significant increase in daily UFN website visits, from ten before the intervention to 27 after it (p < 0.001).Conclusion: The increase in ADR reporting shows that the inclusion of hyperlinks to online ADR reporting forms is an easy and cost-effective way to change health professional behaviours with regard to spontaneous ADR reports. [ABSTRACT FROM AUTHOR]- Published
- 2012
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10. Medical informatics in a united and healthy Europe. Remote diagnosis of children dental problems based on non-invasive photographs -- a valid proceeding?
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Amável R, Cruz-Correia R, Frias-Bulhosa J, Adlassnig K, Blobel B, Mantas J, and Masic I
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- 2009
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11. Integration of hospital data using agent technologies – A case study.
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Cruz-Correia, R., Vieira-Marques, P., Costa, P., Ferreira, A., Oliveira-Palhares, E., Araújo, F., and Costa-Pereira, A.
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INFORMATION retrieval , *MEDICAL records , *HTML (Document markup language) , *PDF (Computer file format) , *ELECTRONIC file management , *INTRANETS (Computer networks) - Abstract
Data retrieval and its integration is one of the major problems that face large and complex health organizations. This is especially relevant when patient information is produced in heterogeneous environments. Implementing a Virtual Electronic Patient Record (VEPR) system may provide an adequate and cost-effective solution for most clinical information needs. In this paper, we describe and discuss the use of agent technologies for the retrieval and integration of clinical records in a VEPR, thus making patient information available at any point of care. Between May 2003 and May 2004, a VEPR was designed and implemented at Hospital S. João, a university hospital with over 1350 beds. An agent-based platform Multi-Agent System for Integration of Data (MAID®) ensures the communication among various hospital information systems. Clinical reports are retrieved from clinical department information systems (DIS) and stored into a central repository in a browser friendly format. Documents are retrieved in HTML and PDF format and are digitally signed at storage. MAID is now running for the last 12 months, regularly scanning 7 DIS and collecting a mean of 2800 new reports each day. A visualization module for the VEPR was made available in October 2004 and the number of users and user sessions has been growing since. Currently, over 340 doctors are using the system on a daily basis. The total budget of the project was less than 400 000 euros. Around 30% of the costs were spent in software development and MAID accounted for only 13% of the total project budget. The use of agent technologies in the implementation of a VEPR enabled the successful integration of a large amount of heterogeneous data that could then be accessed from any workstation in the hospital Intranet. As few changes were required to be made in the existing DIS, the implementation has been done over a relatively short period of time and the stress in the organization was low. Optimization of the scheduling algorithm, automatic notification of health professionals, introspection of clinical reports, retrieval of XML report representations and extension of VEPR to health centres are priorities for future research and development. We strongly believe that agent technologies can and should be used to solve complex data integration and communication problems, which are crucial to the quality of patient care. [ABSTRACT FROM AUTHOR]
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- 2005
12. Determinants of frequency and longevity of hospital encounters' data use
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Wyatt Jeremy C, Cruz-Correia Ricardo J, Dinis-Ribeiro Mario, and Costa-Pereira Altamiro
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background The identification of clinically relevant information enables improvement in user interfaces and in data management. However, it is difficult to identify what information is important in daily clinical care, and what is used occasionally. This study aims to determine for how long clinical documents are used in a Hospital Information System (HIS). Methods The access logs of 3 years of usage of a HIS were analysed concerning report departmental source, type of hospital encounter, and inpatient encounter ICD-9-CM main diagnosis. Reports median life indicates the median time elapsed between information creation and its usage. The models that better explains report views over time were explored. Results The number of report views in the study period was 656 583. Fifty two percent of the reports viewed by medical doctors in emergency encounters were from previous encounters - 21% at outpatient attendance, 19% in inpatient (wards) and 12% during emergency encounters. In an inpatient setting, 20% of the reports viewed were produced in previous encounters. The median life of information in documents is 1.5 days for emergency, 4.8 days for inpatient and 37.8 days for outpatient encounters. Immune-haemotherapy reports reach their median lives faster (7 days) than clinical pathology (15 days), gastroenterology (80 days) and pathology (118 days). The median life of reports produced in inpatient encounters varied from 36 days for neoplasms as the main diagnosis to 0.7 days for injury and poisoning. The model with the best fit (R2 > 0.9) was the exponential. Conclusions The usage of past patient information varied significantly according to patient age, type of information, type of hospital encounter and medical cause (main diagnosis) for the encounter. The exponential model is a good fit to model how the reports are seen over time, so the design of user interfaces and repository management algorithms should take it in consideration.
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- 2010
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13. Control of allergic rhinitis and asthma test – a formal approach to the development of a measuring tool
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Fonseca Joao A, Vaz Marianela, Costa-Pereira Altamiro, Bugalho-Almeida António, Morais-Almeida Mario, Azevedo Luis F, Cruz-Correia Ricardo, Martins Sonia V, and Nogueira-Silva Luis
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Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background The concurrent management of allergic rhinitis and asthma (ARA) has been recommended by Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines. However, a tool capable of assessing simultaneously the control of upper and lower airways diseases is lacking. Aim To describe the studies conducted to design the control of ARA test (CARAT) questionnaire. Methods We performed a literature review to generate a list of potentially important items for the assessment of control of ARA. A formal consensus development process, that used an innovative web-based application, was designed – 111 experts in ARA and 60 patients participated. At the final consensus meeting, 25 primary and secondary care physicians formulated the questions and response options. A qualitative feasibility study (n = 31 patients) was conducted to evaluate the comprehensibility of the questionnaire while testing two different designs. Results Thirty-four potentially important items were identified. All the steps of the consensus process were completed in 2.5 months. The opinions of experts and patients lead to the formulation of 17 questions. At the feasibility study the instructions and wording problems were corrected and a semi-tabular format was chosen. Conclusion A tool to measure the control of allergic rhinitis and asthma was developed using a comprehensive set of methodological steps ensuring the design quality and the face and content validity. Additional validation studies to assess the psychometric properties of the questionnaire have started.
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- 2009
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14. Reviewing the integration of patient data: how systems are evolving in practice to meet patient needs
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Ferreira Ana M, Vieira-Marques Pedro M, Cruz-Correia Ricardo J, Almeida Filipa C, Wyatt Jeremy C, and Costa-Pereira Altamiro M
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background The integration of Information Systems (IS) is essential to support shared care and to provide consistent care to individuals – patient-centred care. This paper identifies, appraises and summarises studies examining different approaches to integrate patient data from heterogeneous IS. Methods The literature was systematically reviewed between 1995–2005 to identify articles mentioning patient records, computers and data integration or sharing. Results Of 3124 articles, 84 were included describing 56 distinct projects. Most of the projects were on a regional scale. Integration was most commonly accomplished by messaging with pre-defined templates and middleware solutions. HL7 was the most widely used messaging standard. Direct database access and web services were the most common communication methods. The user interface for most systems was a Web browser. Regarding the type of medical data shared, 77% of projects integrated diagnosis and problems, 67% medical images and 65% lab results. More recently significantly more IS are extending to primary care and integrating referral letters. Conclusion It is clear that Information Systems are evolving to meet people's needs by implementing regional networks, allowing patient access and integration of ever more items of patient data. Many distinct technological solutions coexist to integrate patient data, using differing standards and data architectures which may difficult further interoperability.
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- 2007
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15. Cross-cultural validation of the Short-Form Vascular Access Questionnaire.
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Barros JP, Fonseca JA, Pinto R, Pratas J, and Cruz-Correia R
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- Humans, Reproducibility of Results, Female, Male, Middle Aged, Aged, Surveys and Questionnaires, Portugal, Adult, Aged, 80 and over, Blood Vessel Prosthesis Implantation, Renal Dialysis, Psychometrics, Patient Satisfaction, Arteriovenous Shunt, Surgical, Predictive Value of Tests, Translating, Cultural Characteristics
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Background: Vascular access (VA) is a central condition for hemodialysis (HD). Screening patients' views regarding their VA is a significant end point for improving the quality of care. The Short-form Vascular Access Questionnaire (SF-VAQ) is a specific questionnaire to assess patients' satisfaction levels regarding their VA., Purpose: This study aims to develop the Portuguese version of the SF-VAQ and assess its psychometric properties., Methods: A forward and back translation was used. A multicentric study was conducted with 156 patients undergoing hemodialysis to psychometric testing. Reliability (internal consistency and test-retest) was assessed using Cronbach's alpha and Intraclass Correlation Coefficient. A construct validity test was conducted using factor analysis. The convergent validity was calculated using the correlation coefficient., Results: An obtained Cronbach's alpha of 0.77 indicates good internal consistency. The test-retest reliability was established using the Intraclass Correlation Coefficient (ICC) of 0.771. The four sub-scales proposed by the instrument's designer were confirmed, which together accounted for 53% of the variance. The correlation with the Visual Analogue Scale was r = 0.895 ( p < 0.001), confirming the convergent validity., Conclusion: The Portuguese version of the SF-VAQ is a valid and reliable instrument with good psychometric properties to be implemented to promote an evaluation of VA satisfaction in HD patients and improve patient care., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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16. Large Language Models in Nursing Education: State-of-the-Art.
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Rodrigues D and Cruz-Correia R
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- Humans, Computer-Assisted Instruction methods, Curriculum, Education, Nursing ethics, Education, Nursing methods, Natural Language Processing, Machine Learning ethics
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This study explores the integration of Large Language Models (LLMs) into nursing education, highlighting a paradigm shift towards interactive learning environments. We aimed to analyze the literature to identify how large language models are being implemented in nursing education, as well as key opportunities and limitations that need to be addressed. English records published since 2022 were retrieved from 4 databases including LLMs in nursing education. A total of 19 records were eligible. As LLMs advanced natural language processing capabilities enable interactive learning experiences, nursing educators are presented with unique opportunities to enhance curriculum delivery, foster critical thinking, and simulate complex clinical scenarios. Through a comprehensive analysis of current applications, limitations and future research, this paper navigates the complexities of adopting LLMs (eg ChatGPT) in nursing education. This paper concludes with a call for action to advance the integration of AI in nursing, enhancing educational outcomes while ensuring ethical, effective use.
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- 2024
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17. Improving Healthcare Quality with a LHS: From Patient-Generated Health Data to Evidence-Based Recommendations.
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Santos RL and Cruz-Correia R
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- Humans, Patient Generated Health Data, Quality Improvement, Wearable Electronic Devices, Electronic Health Records, Evidence-Based Medicine, Health Information Interoperability, Learning Health System
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One approach to enriching the Learning Health System (LHS) is leveraging vital signs and data from wearable technologies. Blood oxygen, heart rate, respiration rates, and other data collected by wearables (like sleep and exercise patterns) can be used to monitor and predict health conditions. This data is already being collected and could be used to improve healthcare in several ways. Our approach will be health data interoperability with HL7 FHIR (for data exchange between different systems), openEHR (to store researchable data separated from software but connected to ontologies, external terminologies and code sets) and maintain the semantics of data. OpenEHR is a standard that has an important role in modelling processes and clinical decisions. The six pillars of Lifestyle Medicine can be a first attempt to change how patients see their daily decisions, affecting the mid to long-term evolution of their health. Our objective is to develop the first stage of the LHS based on a co-produced personal health recording (CoPHR) built on top of a local LLM that interoperates health data through HL7 FHIR, openEHR, OHDSI and terminologies that can ingest external evidence and produces clinical and personal decision support and, when combined with many other patients, can produce or confirm evidence.
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- 2024
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18. Individuals' attitudes toward digital mental health apps and implications for adoption in Portugal: web-based survey.
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Nogueira-Leite D, Marques-Cruz M, and Cruz-Correia R
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- Humans, Portugal, Cross-Sectional Studies, Surveys and Questionnaires, Internet, Mental Health, Mobile Applications
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Background: The literature is consensual regarding the academic community exhibiting higher levels of mental disorder prevalence than the general population. The potential of digital mental health apps for improving access to resources to cope with these issues is ample. However, studies have yet to be performed in Portugal on individuals' attitudes and perceptions toward digital mental health applications or their preferences and decision drivers on obtaining mental health care, self-assessment, or treatment., Objective: This study aims to understand the determinants of digital mental health applications use in the Portuguese academic community of Porto, along with potential adoption barriers and enablers., Methods: A cross-sectional, web-based survey was delivered via dynamic email to the University of Porto's academic community. Data collection occurred between September 20 and October 20, 2022. We used structural equation modeling to build three models, replicating a peer-reviewed and published study and producing a newly full mediation model shaped by the collected data. We tested the relationships between use of digital mental health apps and perceived stress, perceived need to seek help for mental health, perceived stigma, past use of mental health services, privacy concerns, and social influence., Results: Of the 539 participants, 169 (31.4%) reported having used digital mental health apps. Perceived stress and a latent variable, comprising perceptions of mental health problems and coping strategies, were positively associated with mental health app use, while privacy concerns regarding one's information being accessible to others were negatively associated. Perceived stigma, need to seek help, and close relationships did not have a statistically significant direct effect., Conclusions: These findings can inform product and policy development of new, better-targeted digital mental health app interventions, with implications for researchers and academia, industry, and policymakers. Our study concludes that, to maximize adherence to these apps, they should have low to no financial charges, demonstrate evidence of their helpfulness and focus on the timely delivery of care. We also conclude that to foster digital mental health app use, there is a need to improve mental health literacy, namely regarding self-awareness of one's conditions, acceptable stress levels, and overall behavior towards mental health., Trial Registration: RR2-10.2196/41040., (© 2024. The Author(s).)
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- 2024
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19. Fast Healthcare Interoperability Resources-Based Support System for Predicting Delivery Type: Model Development and Evaluation Study.
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Coutinho-Almeida J, Cardoso A, Cruz-Correia R, and Pereira-Rodrigues P
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Background: The escalating prevalence of cesarean delivery globally poses significant health impacts on mothers and newborns. Despite this trend, the underlying reasons for increased cesarean delivery rates, which have risen to 36.3% in Portugal as of 2020, remain unclear. This study delves into these issues within the Portuguese health care context, where national efforts are underway to reduce cesarean delivery occurrences., Objective: This paper aims to introduce a machine learning, algorithm-based support system designed to assist clinical teams in identifying potentially unnecessary cesarean deliveries. Key objectives include developing clinical decision support systems for cesarean deliveries using interoperability standards, identifying predictive factors influencing delivery type, assessing the economic impact of implementing this tool, and comparing system outputs with clinicians' decisions., Methods: This study used retrospective data collected from 9 public Portuguese hospitals, encompassing maternal and fetal data and delivery methods from 2019 to 2020. We used various machine learning algorithms for model development, with light gradient-boosting machine (LightGBM) selected for deployment due to its efficiency. The model's performance was compared with clinician assessments through questionnaires. Additionally, an economic simulation was conducted to evaluate the financial impact on Portuguese public hospitals., Results: The deployed model, based on LightGBM, achieved an area under the receiver operating characteristic curve of 88%. In the trial deployment phase at a single hospital, 3.8% (123/3231) of cases triggered alarms for potentially unnecessary cesarean deliveries. Financial simulation results indicated potential benefits for 30% (15/48) of Portuguese public hospitals with the implementation of our tool. However, this study acknowledges biases in the model, such as combining different vaginal delivery types and focusing on potentially unwarranted cesarean deliveries., Conclusions: This study presents a promising system capable of identifying potentially incorrect cesarean delivery decisions, with potentially positive implications for medical practice and health care economics. However, it also highlights the challenges and considerations necessary for real-world application, including further evaluation of clinical decision-making impacts and understanding the diverse reasons behind delivery type choices. This study underscores the need for careful implementation and further robust analysis to realize the full potential and real-world applicability of such clinical support systems., (©João Coutinho-Almeida, Alexandrina Cardoso, Ricardo Cruz-Correia, Pedro Pereira-Rodrigues. Originally published in JMIR Formative Research (https://formative.jmir.org), 08.04.2024.)
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- 2024
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20. Incorporating ChatGPT in Medical Informatics Education: Mixed Methods Study on Student Perceptions and Experiential Integration Proposals.
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Magalhães Araujo S and Cruz-Correia R
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- Humans, Artificial Intelligence, Educational Status, Faculty, Medical, Medical Informatics, Students, Medical
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Background: The integration of artificial intelligence (AI) technologies, such as ChatGPT, in the educational landscape has the potential to enhance the learning experience of medical informatics students and prepare them for using AI in professional settings. The incorporation of AI in classes aims to develop critical thinking by encouraging students to interact with ChatGPT and critically analyze the responses generated by the chatbot. This approach also helps students develop important skills in the field of biomedical and health informatics to enhance their interaction with AI tools., Objective: The aim of the study is to explore the perceptions of students regarding the use of ChatGPT as a learning tool in their educational context and provide professors with examples of prompts for incorporating ChatGPT into their teaching and learning activities, thereby enhancing the educational experience for students in medical informatics courses., Methods: This study used a mixed methods approach to gain insights from students regarding the use of ChatGPT in education. To accomplish this, a structured questionnaire was applied to evaluate students' familiarity with ChatGPT, gauge their perceptions of its use, and understand their attitudes toward its use in academic and learning tasks. Learning outcomes of 2 courses were analyzed to propose ChatGPT's incorporation in master's programs in medicine and medical informatics., Results: The majority of students expressed satisfaction with the use of ChatGPT in education, finding it beneficial for various purposes, including generating academic content, brainstorming ideas, and rewriting text. While some participants raised concerns about potential biases and the need for informed use, the overall perception was positive. Additionally, the study proposed integrating ChatGPT into 2 specific courses in the master's programs in medicine and medical informatics. The incorporation of ChatGPT was envisioned to enhance student learning experiences and assist in project planning, programming code generation, examination preparation, workflow exploration, and technical interview preparation, thus advancing medical informatics education. In medical teaching, it will be used as an assistant for simplifying the explanation of concepts and solving complex problems, as well as for generating clinical narratives and patient simulators., Conclusions: The study's valuable insights into medical faculty students' perspectives and integration proposals for ChatGPT serve as an informative guide for professors aiming to enhance medical informatics education. The research delves into the potential of ChatGPT, emphasizes the necessity of collaboration in academic environments, identifies subject areas with discernible benefits, and underscores its transformative role in fostering innovative and engaging learning experiences. The envisaged proposals hold promise in empowering future health care professionals to work in the rapidly evolving era of digital health care., (©Sabrina Magalhães Araujo, Ricardo Cruz-Correia. Originally published in JMIR Medical Education (https://mededu.jmir.org), 20.03.2024.)
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- 2024
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21. Economic Impact of a Hospital Cyberattack in a National Health System: Descriptive Case Study.
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Portela D, Nogueira-Leite D, Almeida R, and Cruz-Correia R
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Background: Over the last decade, the frequency and size of cyberattacks in the health care industry have increased, ranging from breaches of processes or networks to encryption of files that restrict access to data. These attacks may have multiple consequences for patient safety, as they can, for example, target electronic health records, access to critical information, and support for critical systems, thereby causing delays in hospital activities. The effects of cybersecurity breaches are not only a threat to patients' lives but also have financial consequences due to causing inactivity in health care systems. However, publicly available information on these incidents quantifying their impact is scarce., Objective: We aim, while using public domain data from Portugal, to (1) identify data breaches in the public national health system since 2017 and (2) measure the economic impact using a hypothesized scenario as a case study., Methods: We retrieved data from multiple national and local media sources on cybersecurity from 2017 until 2022 and built a timeline of attacks. In the absence of public information on cyberattacks, reported drops in activity were estimated using a hypothesized scenario for affected resources and percentages and duration of inactivity. Only direct costs were considered for estimates. Data for estimates were produced based on planned activity through the hospital contract program. We use sensitivity analysis to illustrate how a midlevel ransomware attack might impact health institutions' daily costs (inferring a potential range of values based on assumptions). Given the heterogeneity of our included parameters, we also provide a tool for users to distinguish such impacts of different attacks on institutions according to different contract programs, served population size, and proportion of inactivity., Results: From 2017 to 2022, we were able to identify 6 incidents in Portuguese public hospitals using public domain data (there was 1 incident each year and 2 in 2018). Financial impacts were obtained from a cost point of view, where estimated values have a minimum-to-maximum range of €115,882.96 to €2,317,659.11 (a currency exchange rate of €1=US $1.0233 is applicable). Costs of this range and magnitude were inferred assuming different percentages of affected resources and with different numbers of working days while considering the costs of external consultation, hospitalization, and use of in- and outpatient clinics and emergency rooms, for a maximum of 5 working days., Conclusions: To enhance cybersecurity capabilities at hospitals, it is important to provide robust information to support decision-making. Our study provides valuable information and preliminary insights that can help health care organizations better understand the costs and risks associated with cyber threats and improve their cybersecurity strategies. Additionally, it demonstrates the importance of adopting effective preventive and reactive strategies, such as contingency plans, as well as enhanced investment in improving cybersecurity capabilities in this critical area while aiming to achieve cyber-resilience., (©Diana Portela, Diogo Nogueira-Leite, Rafael Almeida, Ricardo Cruz-Correia. Originally published in JMIR Formative Research (https://formative.jmir.org), 30.06.2023.)
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- 2023
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22. Mental Health Professionals' Attitudes Toward Digital Mental Health Apps and Implications for Adoption in Portugal: Mixed Methods Study.
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Nogueira-Leite D, Diniz JM, and Cruz-Correia R
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Background: Digital health apps are among the most visible facets of the ongoing digital transition in health care, with mental health-focused apps as one of the main therapeutic areas. However, concerns regarding their scientific robustness drove regulators to establish evaluation procedures, with Germany's Digitale Gesundheitsanwendungen program pioneering in app prescription with costs covered by statutory health insurance. Portugal gathers a set of conditions and requirements that position it as an excellent test bed for digital health apps. Its daunting mental health landscape reinforces the potential interest in new interventions. To understand if they would be acceptable, we need to understand the supply side's attitudes and perceptions toward them, that is, those of psychiatrists and psychologists., Objective: This study aims to understand the attitudes and expectations of psychiatrists and psychologists toward digital mental health apps (DMHAs) in the Portuguese context, as well as perceived benefits, barriers, and actions to support their adoption., Methods: We conducted a 2-stage sequential mixed methods study. Stage 1 consisted of a cross-sectional web survey adapted to the Portuguese context that was delivered to mental health professionals and psychologists. Stage 2 complemented the insights of the web survey results with a key opinion leader analysis., Results: A total of 160 complete survey responses were recorded, most of which were from psychologists. This is the most extensive study on mental health professionals' attitudes and perceptions of DMHAs in Portugal. A total of 87.2% (136/156) of the respondents supported the opportunity to prescribe DMHAs. Increased health literacy (139/160, 86.9%), wider adherence to treatment (137/160, 85.6%), and proper disease management (127/160, 79.4%) were the most frequently agreed upon benefits of DMHAs. However, only less than half (68/156, 43.6%) of the respondents planned to prescribe or recommend DMHAs, with psychologists being more favorable than psychiatrists. Professionals faced substantial barriers, such as a lack of information on DMHAs (154/160, 96.3%), the level of initial training effort (115/160, 71.9%), and the need for adjustments of clinical processes and records (113/160, 70.6%). Professionals reported that having more information on the available apps and their suitability for health objectives (151/160, 94.4%), more scientific evidence of the validity of the apps as a health intervention (147/160, 91.9%), and established recommendations of apps by specific clinical guidelines or professional societies (145/160, 90.6%) would be essential to foster adoption., Conclusions: More information about DMHAs regarding their clinical validity and how they work is necessary so that such an intervention can be adopted in Portugal. Recommendations from professional and scientific societies, as well as from governmental bodies, are strongly encouraged. Although the benefits of and the barriers to using these apps are consensual, more evidence, along with further promotion of mental health professionals' digital literacy, is needed., International Registered Report Identifier (irrid): RR2-10.2196/41040., (©Diogo Nogueira-Leite, José Miguel Diniz, Ricardo Cruz-Correia. Originally published in JMIR Human Factors (https://humanfactors.jmir.org), 02.06.2023.)
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- 2023
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23. Corrigendum to "Biomedical and health informatics teaching in Portugal: Current status" [Heliyon 9(3) (March 2023) e14163].
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Costa PD, Almeida J, Araujo SM, Alves P, Cruz-Correia R, Saranto K, and Mantas J
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[This corrects the article DOI: 10.1016/j.heliyon.2023.e14163.]., (© 2023 The Author(s).)
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- 2023
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24. Implementation Status of the Proposal for a Regulation of the European Health Data Space in Portugal: Are We Ready for It?
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Mateus M, Loureiro M, Fernandes AR, Oliveira M, and Cruz-Correia R
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- Portugal, Policy, Electronic Health Records standards
- Abstract
The European Health Data Space (EHDS) proposal aims to establish a set of rules and governance frameworks to promote the use of electronic health data for both primary and secondary purposes. This study aims at analysing the implementation status of the EHDS proposal in Portugal, particularly the points concerning the primary use of health data. The proposal was scanned for the points that gave member states a direct responsibility to implement actions, and a literature review and interviews were conducted to assess the implementation status of these policies in Portugal This study found that Portugal is well advanced in the implementation of policies concerning the rights of natural persons in relation to the primary use of their personal health data, but also identified challenges, which include the lack of a common interoperability framework for the exchange of electronic health data.
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- 2023
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25. Improving Healthcare Quality with an LHS.
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Santos RL and Cruz-Correia R
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- Humans, Electronic Health Records, Learning Health System, Health Records, Personal, Emergency Medical Services
- Abstract
The Learning Health System (LHS) is an important tool to help healthcare professionals solve problems by collecting, analyzing, interpreting and comparing health data, with the objective of helping patients make the best decision based on their own data, given the best evidence available. [1]. We believe partial oxygen saturation of arterial blood (SpO2) and related measurements and calculations can also be candidates for predictions and analysis of health conditions. We intend to build a Personal Health Record (PHR) that can exchange data with Electronic Health Records (EHRs) from hospitals, propose enhanced self-care, seek a support network, or look for healthcare assistance, (primary care or emergency service).
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- 2023
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26. Time optimization in primary care - chronic prescription cost.
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Leite-Costa T, Rodrigues D, Sá F, and Cruz Correia R
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- Humans, Ethnicity, Income, Primary Health Care, Prescriptions, General Practitioners
- Abstract
Introduction: Time optimization is a common goal to most health information institutions. In several countries, chronic electronic renewal prescriptions were one of the main focuses when implementing information systems. In Portugal, Electronic Medical Prescription (PEM®) software is used for most electronic prescriptions. This study aims to quantify the time spent in chronic prescription renewal appointments (CPRA) in primary care and its impact in the Portuguese National Health System (SNS)., Methods: Eight general practitioners (GP) were included in the study during February 2022. The average duration of 100 CPRA was obtained. To determine the number of CPRA performed every year, a primary care BI-CSP® platform was used. Using Standard Cost Model and average medical doctor hourly rate in Portugal we estimated CPRA global costs., Results: Each doctor spent on average 1:55 ± 01:07 min per CPRA. There were 8295 GP working in 2022. A total 635 561 CPRA were performed in 2020 and 774 346 in 2021. In 2020, CPRA costs ranged 303 088 ± 179 419€, and in 2021 that number increased to 369 272 ± 218 599€., Conclusion: This is the first study to quantify CPRA's real cost in Portugal. A PEM® software update would allow daily savings, ranging from 830€ (± 491€) in 2020 and 1011€ (± 598€) in 2021. That change could allow hiring 8 ± 5 GP in 2020 and 12 ± 7 in 2021., (© 2023. The Author(s).)
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- 2023
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27. COVID-19 Contact Tracing as an Indicator for Evaluating a Pandemic Situation: Simulation Study.
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Marques-Cruz M, Nogueira-Leite D, Alves JM, Fernandes F, Fernandes JM, Almeida MÂ, Cunha Correia P, Perestrelo P, Cruz-Correia R, and Pita Barros P
- Subjects
- Humans, Contact Tracing, Communicable Disease Control, Pandemics prevention & control, SARS-CoV-2, COVID-19 epidemiology
- Abstract
Background: Contact tracing is a fundamental intervention in public health. When systematically applied, it enables the breaking of chains of transmission, which is important for controlling COVID-19 transmission. In theoretically perfect contact tracing, all new cases should occur among quarantined individuals, and an epidemic should vanish. However, the availability of resources influences the capacity to perform contact tracing. Therefore, it is necessary to estimate its effectiveness threshold. We propose that this effectiveness threshold may be indirectly estimated using the ratio of COVID-19 cases arising from quarantined high-risk contacts, where higher ratios indicate better control and, under a threshold, contact tracing may fail and other restrictions become necessary., Objective: This study assessed the ratio of COVID-19 cases in high-risk contacts quarantined through contact tracing and its potential use as an ancillary pandemic control indicator., Methods: We built a 6-compartment epidemiological model to emulate COVID-19 infection flow according to publicly available data from Portuguese authorities. Our model extended the usual susceptible-exposed-infected-recovered model by adding a compartment Q with individuals in mandated quarantine who could develop infection or return to the susceptible pool and a compartment P with individuals protected from infection because of vaccination. To model infection dynamics, data on SARS-CoV-2 infection risk (IR), time until infection, and vaccine efficacy were collected. Estimation was needed for vaccine data to reflect the timing of inoculation and booster efficacy. In total, 2 simulations were built: one adjusting for the presence and absence of variants or vaccination and another maximizing IR in quarantined individuals. Both simulations were based on a set of 100 unique parameterizations. The daily ratio of infected cases arising from high-risk contacts (q estimate) was calculated. A theoretical effectiveness threshold of contact tracing was defined for 14-day average q estimates based on the classification of COVID-19 daily cases according to the pandemic phases and was compared with the timing of population lockdowns in Portugal. A sensitivity analysis was performed to understand the relationship between different parameter values and the threshold obtained., Results: An inverse relationship was found between the q estimate and daily cases in both simulations (correlations >0.70). The theoretical effectiveness thresholds for both simulations attained an alert phase positive predictive value of >70% and could have anticipated the need for additional measures in at least 4 days for the second and fourth lockdowns. Sensitivity analysis showed that only the IR and booster dose efficacy at inoculation significantly affected the q estimates., Conclusions: We demonstrated the impact of applying an effectiveness threshold for contact tracing on decision-making. Although only theoretical thresholds could be provided, their relationship with the number of confirmed cases and the prediction of pandemic phases shows the role as an indirect indicator of the efficacy of contact tracing., (©Manuel Marques-Cruz, Diogo Nogueira-Leite, João Miguel Alves, Francisco Fernandes, José Miguel Fernandes, Miguel Ângelo Almeida, Patrícia Cunha Correia, Paula Perestrelo, Ricardo Cruz-Correia, Pedro Pita Barros. Originally published in JMIR Public Health and Surveillance (https://publichealth.jmir.org), 06.04.2023.)
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- 2023
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28. Biomedical and health informatics teaching in Portugal: Current status.
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Costa PD, Almeida J, Araujo SM, Alves P, Cruz-Correia R, Saranto K, and Mantas J
- Abstract
Background: The domain of Biomedical and Health Informatics (BMHI) lies in the intersection of multiple disciplines, making it difficult to define and, consequently, characterise the workforce, training needs and requirements in this domain. Nevertheless, to the best of our knowledge, there isn't any aggregated information about the higher education programmes in BMHI currently being delivered in Portugal, and which knowledge, skills, and competencies these programmes aim to develop., Aim: Our aim is to map BMHI teaching in Portugal. More specifically, our objective is to identify and characterise the: a.) programmes delivering relevant BMHI teaching; b.) geographical distribution and chronological evolution of such programmes; and c.) credit distribution and weight., Methods: We conducted a descriptive, cross-sectional study to systematically identify all programmes currently delivering any core BMHI modules in Portugal. Our population included all graduate-level programmes being delivered in the 2021/2022 academic year in any Portuguese higher education institution., Results: We identified 23 programmes delivering relevant teaching in BMHI in Portugal. Of these, eight (35%) were classified as dedicated educational programmes in BMHI, mostly delivered in polytechnic institutes at a master's level (5; 63%) and located preferentially in the northern part of the country (7). Currently, there are four programmes with potential for accreditation but still requiring some workload increase in certain areas in order to be eligible., Competing Interests: Paulo Dias Costa, João Almeida, Sabrina Magalhães Araújo, Patrícia Alves and Ricardo Cruz Correia are affiliated with the Faculty of Medicine at University of Porto. João Almeida, Sabrina Magalhães Araújo and Ricardo Cruz Correia are actively involved in teaching delivery to the ‘Medical Informatics’ master’s programme at the University of Porto. Ricardo Cruz Correia is the course director of the ‘Medical Informatics’ master’s programme at the University of Porto. John Mantas is the working group chair on education for the ‘European Federation for Medical Informatics’., (© 2023 The Authors.)
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- 2023
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29. Attitudes of Physicians and Individuals Toward Digital Mental Health Tools: Protocol for a Web-Based Survey Research Project.
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Nogueira-Leite D and Cruz-Correia R
- Abstract
Background: Digital transformation is impacting health care delivery. Great market dynamism is bringing opportunities and concerns alike into public discussion. Digital health apps are a vibrant segment where regulation is emerging, with Germany paving the way with its DiGA (Digitale Gesundheitsanwendungen, in German, meaning digital health apps) program. Simultaneously, mental ill-health constitutes a global health concern, and prevalence is expected to worsen due to the COVID-19 pandemic and its containment measures. Portugal and its National Health System may be a useful testbed for digital health interventions., Objective: The paper outlines the protocol for a research project on the attitudes of physicians and potential users toward digital mental health apps to improve access to care, patient outcomes, and reduce the burden of disease of mental ill-health., Methods: Web surveys will be conducted to acquire data from the main stakeholders (physicians and the academic community). Data analysis will replicate the statistical analysis performed in the studies from Dahlhausen and Borghouts to derive conclusions regarding the relative acceptance and likelihood of successful implementation of digital mental health apps in Portugal., Results: The findings of the proposed studies will elicit important information on how physicians and individuals perceive digital mental health app interventions to improve access to care, patient outcomes, and reduce the burden of disease of mental ill-health. Data collection ran between September 26 and November 6, 2022, for the first study and September 20 and October 20, 2022, for the second study. We obtained 160 responses to the first study's survey and 539 answers to the second study's survey. Data analysis is concluded, and both studies' results are expected to be published in 2023., Conclusions: The results of the studies projected in this research protocol will have implications for researchers and academia, industry, and policy makers concerning the adoption and implementation of digital health mental apps and associated interventions., International Registered Report Identifier (irrid): DERR1-10.2196/41040., (©Diogo Nogueira-Leite, Ricardo Cruz-Correia. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 14.03.2023.)
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- 2023
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30. Assessing the Use of Hospital Information Systems (HIS) to Support Decision-Making: A Cross-Sectional Study in Public Hospitals in the Huíla Health Region of Southern Angola.
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Sanjuluca THP, de Almeida AA, and Cruz-Correia R
- Abstract
Hospital information systems could be relevant tools to inform hospital managers, support better management decisions in healthcare, and increase efficiency. Nonetheless, hospital managers' effective use of these systems to support decision-making in Angola is unknown. Our study aimed to analyse the use of hospital information systems as a tool to support decision-making by hospital managers in Huíla, Angola. It was a descriptive, cross-sectional study inducted between July and September 2017 in seven hospitals in Huíla Province, Angola, specifically in the cities of Lubango and Matala. Thirty-six members of the hospital boards filled out a self-questionnaire that consisted of twenty questions based on the following issues: Characterisation of the interviewee's profile; availability of information in the institution; and quality and usefulness of the available operational information. At least two thirds of the participants reported being unsatisfied or relatively satisfied with each assessed hospital information systems-specific feature. More than 50% have rarely or never used the health information system to support decision-making. Most managers do not use hospital information systems to support management-related decision-making in Angola. Improving the ability of hospital information systems to compute adequate indicators and training for hospital managers could be targets for future interventions to support better management-related decision-making in Angolan healthcare.
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- 2022
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31. COVID-19 and Cybersecurity: Finally, an Opportunity to Disrupt?
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Ferreira A and Cruz-Correia R
- Abstract
COVID-19 has challenged cybersecurity to meet the ultimate need of guaranteeing the privacy and security of human beings. Although personal and sensitive health data are needed to better understand, detect, and control the disease, many related cybersecurity challenges and vulnerabilities require further analysis and proper discussion. The aims of this viewpoint are to explore the consequences of COVID-19 on cybersecurity and health care as well as to foster awareness regarding the need for a change in paradigm on how cybersecurity is approached. Education and information technology literacy are important when they are suitably provided; however, they are certainly not a complete solution. Disruption needs to occur at the core of human-device interactions. Building trust, providing novel means to interact with technology (eg, digital humans), and supporting people-the most important cybersecurity asset-are only some of the recommendations for a more human and resilient approach to cybersecurity, during or after the pandemic., Competing Interests: Conflicts of Interest: None declared., (©Ana Ferreira, Ricardo Cruz-Correia. Originally published in JMIRx Med (https://med.jmirx.org), 06.05.2021.)
- Published
- 2021
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32. Teaching Cardiopulmonary Auscultation to Medical Students using a Virtual Patient Simulation Technology.
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Pereira D, Amelia-Ferreira M, Cruz-Correia R, and Coimbra M
- Subjects
- Auscultation, Humans, Technology, Patient Simulation, Students, Medical
- Abstract
The teaching process of auscultation is complex in itself, and difficult to operate since it requires a wide spectrum of patients with the most diverse cardiopulmonary pathologies, readily available during teaching and assessment hours, for an ever-growing number of medical students. In this paper we will focus on how virtual patient technologies can promote the evolution of the current teaching methodologies, promoting better learning. The chosen methodology was: a) a review of available medical simulation technologies for auscultation teaching; b) a case study illustrating how a virtual patient simulation technology has been successfully used to teach and certify auscultation skills. Results show the positive impact and high acceptability of virtual patient simulation technologies in the teaching of auscultation to medical students.
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- 2020
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33. Simulation of the effects of COVID-19 testing rates on hospitalizations.
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Sousa-Pinto B, Fonseca JA, Oliveira B, Cruz-Correia R, Rodrigues PP, Costa-Pereira A, and Rocha-Gonçalves FN
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- Betacoronavirus, COVID-19, COVID-19 Testing, Capacity Building organization & administration, Computer Simulation, Coronavirus Infections prevention & control, Humans, Intensive Care Units statistics & numerical data, Pandemics prevention & control, Pneumonia, Viral prevention & control, SARS-CoV-2, World Health Organization, Clinical Laboratory Techniques, Coronavirus Infections diagnosis, Coronavirus Infections epidemiology, Hospitalization statistics & numerical data, Pneumonia, Viral diagnosis, Pneumonia, Viral epidemiology
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- 2020
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34. OpenEHR and General Data Protection Regulation: Evaluation of Principles and Requirements.
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Gonçalves-Ferreira D, Sousa M, Bacelar-Silva GM, Frade S, Antunes LF, Beale T, and Cruz-Correia R
- Abstract
Background: Concerns about privacy and personal data protection resulted in reforms of the existing legislation in the European Union (EU). The General Data Protection Regulation (GDPR) aims to reform the existing directive on the topic of personal data protection of EU citizens with a strong emphasis on more control of the citizens over their data and in the establishment of rules for the processing of personal data. OpenEHR is a standard that embodies many principles of interoperable and secure software for electronic health records (EHRs) and has been advocated as the best approach for the development of hospital information systems., Objective: This study aimed to understand to what extent the openEHR standard can help in the compliance of EHR systems to the GDPR requirements., Methods: A list of requirements for an EHR to support GDPR compliance and also a list of the openEHR design principles were made. The requirements were categorized and compared with the principles by experts on openEHR and GDPR., Results: A total of 50 GDPR requirements and 8 openEHR design principles were identified. The openEHR principles conformed to 30% (15/50) of GDPR requirements. All the openEHR principles were aligned with GDPR requirements., Conclusions: This study showed that the openEHR principles conform well to GDPR, underlining the common wisdom that truly realizing security and privacy requires it to be built in from the start. By using an openEHR-based EHR, the institutions are closer to becoming compliant with GDPR while safeguarding the medical data., (©Duarte Gonçalves-Ferreira, Mariana Sousa, Gustavo M Bacelar-Silva, Samuel Frade, Luís Filipe Antunes, Thomas Beale, Ricardo Cruz-Correia. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 25.03.2019.)
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- 2019
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35. The Role of Anatomy Computer-Assisted Learning on Spatial Abilities of Medical Students.
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Guimarães B, Firmino-Machado J, Tsisar S, Viana B, Pinto-Sousa M, Vieira-Marques P, Cruz-Correia R, and Ferreira MA
- Subjects
- Adult, Cardiovascular System anatomy & histology, Education, Medical, Undergraduate methods, Female, Humans, Male, Musculoskeletal System anatomy & histology, Prospective Studies, Students, Medical statistics & numerical data, Young Adult, Anatomy education, Computer-Assisted Instruction, Learning physiology, Spatial Navigation physiology, Students, Medical psychology
- Abstract
Currently, medical education context poses different challenges to anatomy, contributing to the introduction of new pedagogical approaches, such as computer-assisted learning (CAL). This approach provides insight into students' learning profiles and skills that enhance anatomy knowledge acquisition. To understand the influence of anatomy CAL on spatial abilities, a study was conducted. A total of 671 medical students attending Musculoskeletal (MA) and Cardiovascular Anatomy (CA) courses, were allocated to one of three groups (MA Group, CA Group, MA + CA Group). Students' pre-training and post-training spatial abilities were assessed through Mental Rotations Test (MRT), with scores ranging between 0-24. After CAL training sessions, students' spatial abilities performance improved (9.72 ± 4.79 vs. 17.05 ± 4.57, P < 0.001). Although male students in both MA Group and CA Group show better baseline spatial abilities, no sex differences were found after CAL training. The improvement in spatial abilities score between sessions (Delta MRT) was correlated with Musculoskeletal Anatomy training sessions in MA Group (r = 0.333, P < 0.001) and MA + CA Group (r = 0.342, P < 0.001), and with Cardiovascular Anatomy training sessions in CA Group (r = 0.461, P = 0.001) and MA + CA Group (r = 0.324, P = 0.001). Multiple linear regression models were used, considering the Delta MRT as dependent variable. An association of Delta MRT to the amount of CAL training and the baseline spatial abilities was observed. The results suggest that CAL training in anatomy has positive dose-dependent effect on spatial abilities., (© 2018 American Association of Anatomists.)
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- 2019
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36. Performance equivalency between computer-based and traditional pen-and-paper assessment: A case study in clinical anatomy.
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Guimarães B, Ribeiro J, Cruz B, Ferreira A, Alves H, Cruz-Correia R, Madeira MD, and Ferreira MA
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- Adult, Comprehension, Computers, Curriculum, Education, Medical, Undergraduate methods, Educational Measurement statistics & numerical data, Female, Humans, Learning, Male, Portugal, Program Evaluation, Software, Surveys and Questionnaires, Young Adult, Anatomy education, Education, Medical, Undergraduate organization & administration, Educational Measurement methods, Schools, Medical organization & administration, Students, Medical statistics & numerical data
- Abstract
The time, material, and staff-consuming nature of anatomy's traditional pen-and-paper assessment system, the increase in the number of students enrolling in medical schools and the ever-escalating workload of academic staff have made the use of computer-based assessment (CBA) an attractive proposition. To understand the impact of such shift in the assessment method, an experimental study evaluating its effect on students' performance was designed. Additionally, students' opinions toward CBA were gathered. Second-year medical students attending a Clinical Anatomy course were randomized by clusters in two groups. The pen-and-paper group attended two sessions, each consisting of a traditional sectional anatomy steeplechase followed by a theoretical examination, while the computer group was involved in two similar sessions conducted in a computerized environment. At the end of each of the computer sessions, students in this group filled an anonymous questionnaire. In the first session, pen-and-paper group students scored significantly better than computer-group students in both the steeplechase (mean ± standard deviation: 66.00 ± 14.15% vs. 43.50 ± 19.10%; P < 0.001) and the theoretical examination (52.50 ± 12.70% vs. 39.00 ± 21.10%; P < 0.001). In the second session, no statistically significant differences were found for both the steeplechase (59.50 ± 17.30% vs. 54.50 ± 17.00%; P = 0.085) and the theoretical examination (57.50 ± 13.70% vs. 54.00 ± 14.30%; P = 0.161). Besides, an intersession improvement in students' perceptions toward CBA was registered. These results suggest that, after a familiarization period, CBA might be a performance equivalent and student accepted alternative to clinical anatomy pen-and-paper theoretical and practical examinations. Anat Sci Educ 11: 124-136. © 2017 American Association of Anatomists., (© 2017 American Association of Anatomists.)
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- 2018
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37. Challenges in Design and Creation of Genetic openEHR-Archetype.
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Maranhão PA, Bacelar-Silva G, Gonçalves-Ferreira D, Vieira-Marques P, and Cruz-Correia R
- Subjects
- Humans, Semantics, Data Mining, Electronic Health Records, Genomics
- Abstract
Since the Human Genomic Project discovered the sequencing of human genome, the interest about genome content in clinical practice has increased. Genetic information has become a key point to understand diseases or improve treatments, for example, the nutrigenomic and nutrigenetics. However, the huge amount of data generated raises the need for Electronic Health Record (EHR) improvements as it becomes increasingly necessary that it includes more specific genetic information. Thus, we aim to propose standard genetic archetypes (in openEHR) and describe our main challenges in this context. We assessed 2 bibliographical databases (Pubmed and Web of science) to determine the main clinical statements needed to create the archetypes. The clinical statements were organized in archetype-concepts, and they were created in openEHR archetype editor. One archetype - genetic test results - was created from a set of genetic data and submitted to CKM repository for review. Based on the modeled archetypes, an openEHR template can be created from the proposed archetype, mainly in the nutrigenomic area, genetic labs and others related to genetic.
- Published
- 2018
38. HS.Register - An Audit-Trail Tool to Respond to the General Data Protection Regulation (GDPR).
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Gonçalves-Ferreira D, Leite M, Santos-Pereira C, Correia ME, Antunes L, and Cruz-Correia R
- Subjects
- Computers, Hospital Information Systems, Hospitals, Humans, Computer Security, Software
- Abstract
Introduction The new General Data Protection Regulation (GDPR) compels health care institutions and their software providers to properly document all personal data processing and provide clear evidence that their systems are inline with the GDPR. All applications involved in personal data processing should therefore produce meaningful event logs that can later be used for the effective auditing of complex processes. Aim This paper aims to describe and evaluate HS.Register, a system created to collect and securely manage at scale audit logs and data produced by a large number of systems. Methods HS.Register creates a single audit log by collecting and aggregating all kinds of meaningful event logs and data (e.g. ActiveDirectory, syslog, log4j, web server logs, REST, SOAP and HL7 messages). It also includes specially built dashboards for easy auditing and monitoring of complex processes, crossing different systems in an integrated way, as well as providing tools for helping on the auditing and on the diagnostics of difficult problems, using a simple web application. HS.Register is currently installed at five large Portuguese Hospitals and is composed of the following open-source components: HAproxy, RabbitMQ, Elasticsearch, Logstash and Kibana. Results HS.Register currently collects and analyses an average of 93 million events per week and it is being used to document and audit HL7 communications. Discussion Auditing tools like HS.Register are likely to become mandatory in the near future to allow for traceability and detailed auditing for GDPR compliance.
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- 2018
39. openEHR Based Systems and the General Data Protection Regulation (GDPR).
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Sousa M, Ferreira D, Santos-Pereira C, Bacelar G, Frade S, Pestana O, and Cruz-Correia R
- Subjects
- Delivery of Health Care, Hospital Information Systems, Humans, Software, Computer Security, Electronic Health Records
- Abstract
The concerns about privacy and personal data protection resulted in reforms of the existing legislation in European Union (EU). The General Data Protection Regulation (GDPR) aims to reform the existing measures on the topic of personal data protection of the European Union citizens, with a strong input on the rights and freedoms of people and in the establishment of rules for the processing of personal data. OpenEHR is a standard that embodies many principles of interoperable and secure software for electronic health records. This work aims to understand to what extent the openEHR standard can be considered a solution for the requirements needed by GDPR. A list of requirements for a Hospital Information Systems (HIS) compliant with GDPR and an identification of openEHR specifications was made. The requirements were categorized and compared with the specifications. The requirements identified for the systems were matched with the openEHR specifications, which result in 16 requirements matched with openEHR. All the specifications identified matched at least one requirement. OpenEHR is a solution for the development of HIS that reinforce privacy and personal data protection, ensuring that they are contemplated in the system development. The institutions can secure that their Eletronic Health Record are compliant with GDPR while safeguarding the medical data quality and, as a result, the healthcare delivery.
- Published
- 2018
40. Teaching cardiopulmonary auscultation in workshops using a virtual patient simulation technology - A pilot study.
- Author
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Pereira D, Gomes P, Faria S, Cruz-Correia R, and Coimbra M
- Subjects
- Adolescent, Adult, Aged, Cardiovascular Diseases diagnosis, Child, Child, Preschool, Clinical Competence, Computer Simulation, Humans, Middle Aged, Pilot Projects, Teaching, Young Adult, Auscultation methods, Patient Simulation, Technology education, Technology methods, User-Computer Interface
- Abstract
Auscultation is currently both a powerful screening tool, providing a cheap and quick initial assessment of a patient's clinical condition, and a hard skill to master. The teaching of auscultation in Universities is today reduced to an unsuitable number of hours. Virtual patient simulators can potentially mitigate this problem, by providing an interesting high-quality alternative to teaching with real patients or patient simulators. In this paper we evaluate the pedagogical impact of using a virtual patient simulation technology in a short workshop format for medical students, training them to detect cardiac pathologies. Results showed a significant improvement (+16%) in the differentiation between normal and pathological cases, although longer duration formats seem to be needed to accurately identify specific pathologies.
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- 2016
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41. How to promote adverse drug reaction reports using information systems - a systematic review and meta-analysis.
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Ribeiro-Vaz I, Silva AM, Costa Santos C, and Cruz-Correia R
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- Humans, Adverse Drug Reaction Reporting Systems, Advertising, Pharmacovigilance
- Abstract
Background: Adverse drug reactions (ADRs) are a well-recognized public health problem and a major cause of death and hospitalization in developed countries. The safety of a new drug cannot be established until it has been on the market for several years. Keeping drug reactions under surveillance through pharmacovigilance systems is indispensable. However, underreporting is a major issue that undermines the effectiveness of spontaneous reports. Our work presents a systematic review on the use of information systems for the promotion of ADR reporting. The aim of this work is to describe the state of the art information systems used to promote adverse drug reaction reporting., Methods: A systematic review was performed with quantitative analysis of studies describing or evaluating the use of information systems to promote adverse drug reaction reporting. Studies with data related to the number of ADRs reported before and after each intervention and the follow-up period were included in the quantitative analysis., Results: From a total of 3865 articles, 33 articles were included in the analysis; these articles described 29 different projects. Most of the projects were on a regional scale (62 %) and were performed in a hospital context (52 %). A total of 76 % performed passive promotion of ADR reporting and used web-based software (55 %). A total of 72 % targeted healthcare professionals and 24 % were oriented to patient ADR reporting. We performed a meta-analysis of 7 of the 29 projects to calculate the aggregated measure of the ADR reporting increase, which had an overall measure of 2.1 (indicating that the interventions doubled the number of ADRs reported)., Conclusions: We found that most of the projects performed passive promotion of ADR reporting (i.e., facilitating the process). They were developed in hospitals and were tailored to healthcare professionals. These interventions doubled the number of ADR reports. We believe that it would be useful to develop systems to assist healthcare professionals with completing ADR reporting within electronic health records because this approach seems to be an efficient method to increase the ADR reporting rate. When this approach is not possible, it is essential to have a tool that is easily accessible on the web to report ADRs. This tool can be promoted by sending emails or through the inclusion of direct hyperlinks on healthcare professionals' desktops.
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- 2016
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42. Promoting adverse drug reaction reporting: comparison of different approaches.
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Ribeiro-Vaz I, Santos CC, and Cruz-Correia R
- Subjects
- Cost-Benefit Analysis, Health Personnel, Humans, Pharmacovigilance, Portugal, Adverse Drug Reaction Reporting Systems economics, Adverse Drug Reaction Reporting Systems instrumentation, Drug Monitoring methods, Drug-Related Side Effects and Adverse Reactions
- Abstract
Objective: To describe different approaches to promote adverse drug reaction reporting among health care professionals, determining their cost-effectiveness., Methods: We analyzed and compared several approaches taken by the Northern Pharmacovigilance Centre (Portugal) to promote adverse drug reaction reporting. Approaches were compared regarding the number and relevance of adverse drug reaction reports obtained and costs involved. Costs by report were estimated by adding the initial costs and the running costs of each intervention. These costs were divided by the number of reports obtained with each intervention, to assess its cost-effectiveness., Results: All the approaches seem to have increased the number of adverse drug reaction reports. We noted the biggest increase with protocols (321 reports, costing 1.96 € each), followed by first educational approach (265 reports, 20.31 €/report) and by the hyperlink approach (136 reports, 15.59 €/report). Regarding the severity of adverse drug reactions, protocols were the most efficient approach, costing 2.29 €/report, followed by hyperlinks (30.28 €/report, having no running costs). Concerning unexpected adverse drug reactions, the best result was obtained with protocols (5.12 €/report), followed by first educational approach (38.79 €/report)., Conclusions: We recommend implementing protocols in other pharmacovigilance centers. They seem to be the most efficient intervention, allowing receiving adverse drug reactions reports at lower costs. The increase applied not only to the total number of reports, but also to the severity, unexpectedness and high degree of causality attributed to the adverse drug reactions. Still, hyperlinks have the advantage of not involving running costs, showing the second best performance in cost per adverse drug reactions report.
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- 2016
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43. An adaptive scheduling model for a multi-agent based VEPR data collection actions.
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Vieira-Marques P, Jácome J, Hilário-Patriarca J, and Cruz-Correia R
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- Health Records, Personal, Meaningful Use, Systems Integration, Electronic Health Records organization & administration, Information Storage and Retrieval methods, Internet organization & administration, Medical Record Linkage methods, Models, Organizational, User-Computer Interface
- Abstract
With the purpose of improving the access to departmental legacy information systems, a multi agent based Virtual Electronic Patient Record (VEPR) was deployed at a major Portuguese Hospital. The agent module (MAID) is in charge of identifying new data produced (reports), collecting and making it available through an integrated web interface. The deployed MAID system uses a static interval for checking the existence of new data, however from the gathered data regarding each department data production it is observable a variable rate throughout the day. In order to address this variability an adaptive model was developed and tested in a simulated environment with real data. The model takes in consideration the past report production profiles for determining a variable query frequency in order to reduce the average time to make data available minimizing the number of departmental requests.
- Published
- 2015
44. Analysis of the quality of hospital information systems Audit Trails.
- Author
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Cruz-Correia R, Boldt I, Lapão L, Santos-Pereira C, Rodrigues PP, Ferreira AM, and Freitas A
- Subjects
- Adult, Humans, Interview, Psychological, Portugal, Hospital Information Systems standards, Hospitals standards, Medical Audit standards
- Abstract
Background: Audit Trails (AT) are fundamental to information security in order to guarantee access traceability but can also be used to improve Health information System's (HIS) quality namely to assess how they are used or misused. This paper aims at analysing the existence and quality of AT, describing scenarios in hospitals and making some recommendations to improve the quality of information., Methods: The responsibles of HIS for eight Portuguese hospitals were contacted in order to arrange an interview about the importance of AT and to collect audit trail data from their HIS. Five institutions agreed to participate in this study; four of them accepted to be interviewed, and four sent AT data. The interviews were performed in 2011 and audit trail data sent in 2011 and 2012. Each AT was evaluated and compared in relation to data quality standards, namely for completeness, comprehensibility, traceability among others. Only one of the AT had enough information for us to apply a consistency evaluation by modelling user behaviour., Results: The interviewees in these hospitals only knew a few AT (average of 1 AT per hospital in an estimate of 21 existing HIS), although they all recognize some advantages of analysing AT. Four hospitals sent a total of 7 AT - 2 from Radiology Information System (RIS), 2 from Picture Archiving and Communication System (PACS), 3 from Patient Records. Three of the AT were understandable and three of the AT were complete. The AT from the patient records are better structured and more complete than the RIS/PACS., Conclusions: Existing AT do not have enough quality to guarantee traceability or be used in HIS improvement. Its quality reflects the importance given to them by the CIO of healthcare institutions. Existing standards (e.g. ASTM:E2147, ISO/TS 18308:2004, ISO/IEC 27001:2006) are still not broadly used in Portugal.
- Published
- 2013
- Full Text
- View/download PDF
45. Challenges of a mobile application for asthma and allergic rhinitis patient enablement-interface and synchronization.
- Author
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Burnay E, Cruz-Correia R, Jacinto T, Sousa AS, and Fonseca J
- Subjects
- Asthma drug therapy, Cell Phone, Humans, Pilot Projects, Portugal, Rhinitis, Allergic, Rhinitis, Allergic, Perennial drug therapy, Self Care instrumentation, Self Care methods, Software, Asthma physiopathology, Rhinitis, Allergic, Perennial physiopathology, Surveys and Questionnaires, Telemedicine, User-Computer Interface
- Abstract
Background: Asthma and allergic rhinitis (ARA) are common inflammatory diseases of the airways. Enhancement of a patient's participation on clinical decisions is related to better results in control of diseases. To control ARA, patients should monitor their symptoms, avoid triggers, and follow their treatment plan. This study described the challenges of developing a mobile application, called m.Carat, that records the main events related to ARA., Materials and Methods: The mobile application m.Carat was developed for Android™ (Google, Mountain View, CA) and iPhone(®) (Apple, San Jose, CA) smartphones. It was developed using PhoneGap, which allows the development of applications for several mobile operating systems. To generate the user interface, jQuery Mobile, HTML, Javascript, and CSS were used. Despite the use of mobile development frameworks, some input and output elements had to be improved. To evaluate the interface, a pilot study was performed with eight users who performed 10 different tasks in the application. To synchronize m.Carat with an online database, an algorithm was developed from scratch. This feature represents a major challenge because all the changes must be reflected in all devices., Results: Currently m.Carat is a mobile application where ARA patients fill out a questionnaire to assess the degree of control of ARA and record their exacerbations, triggers, symptoms, medications, lung function tests, and visits to the doctor or the hospital. They also can receive information and news about ARA, define medication and tasks notifications, and synchronize all records at caratnetwork.org with an online database. The evaluation showed some of the adopted solutions to improve interface usability did not work as expected. Of the 80 total tasks tested the users had no difficulty in 37(46%). Most of the problems observed were easily solved., Conclusions: m.Carat is a mobile application for ARA that may contribute to patient enablement. The development of m.Carat suggests that mobile applications may introduce specific challenges that need new solutions.
- Published
- 2013
- Full Text
- View/download PDF
46. Extracting BI-RADS Features from Portuguese Clinical Texts.
- Author
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Nassif H, Cunha F, Moreira IC, Cruz-Correia R, Sousa E, Page D, Burnside E, and Dutra I
- Abstract
In this work we build the first BI-RADS parser for Portuguese free texts, modeled after existing approaches to extract BI-RADS features from English medical records. Our concept finder uses a semantic grammar based on the BIRADS lexicon and on iterative transferred expert knowledge. We compare the performance of our algorithm to manual annotation by a specialist in mammography. Our results show that our parser's performance is comparable to the manual method.
- Published
- 2012
- Full Text
- View/download PDF
47. Organs transplantation - how to improve the process?
- Author
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Ferraz V, Oliveira G, Viera-Marques P, and Cruz-Correia R
- Subjects
- Access to Information, Databases, Factual, Humans, Internet, Models, Organizational, Portugal, Software, Systems Integration, Tissue Donors, Organ Transplantation methods, Tissue and Organ Procurement methods
- Abstract
The transplant of cadaveric organs must be performed in a short period of time in order to achieve satisfactory results. In Hospital S. João (HSJ), a large Portuguese hospital, during 2008 and 2009, 65 and 61 respectively potential donors were identified, but 12 and 19 of them were not validated as such in time. The number of validated donors could increase if the information workflow between donor hospitals and coordinator offices became more efficient. The goal of this work is to design and implement a multi-agent software platform to assist the information workflow between donor hospitals and coordinator offices. Through several meetings with HSJ coordinator office it was characterized a set of basic data that would allow coordinator offices to early identify possible organs donors. This preliminary characterization provided the necessary grounds for the development of an agent based software application allowing the storage and management of potential donors' information and optimizing the information workflow. The information workflow and the current communication processes characterization allowed the development of a multi-agent web platform, providing a way to assist the information workflow, between coordinator hospitals and their attached hospitals network. The platform also improves direct communication between coordinator offices about most relevant facts. By using this tool or a similar one the information workflow between donor hospitals and coordinator offices can become more efficient, optimizing the pre-transplantation tasks and consequently the number of successful transplants in our country.
- Published
- 2011
48. Traceability of patient records usage: barriers and opportunities for improving user interface design and data management.
- Author
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Cruz-Correia R, Lapão L, and Rodrigues PP
- Subjects
- Data Collection, Hospitals, Humans, Information Storage and Retrieval, Medical Audit, Medical Errors prevention & control, Portugal, Program Evaluation, Quality Assurance, Health Care, Reproducibility of Results, User-Computer Interface, Hospital Administration, Medical Informatics methods, Medical Records Systems, Computerized
- Abstract
Although IT governance practices (like ITIL, which recommends on the use of audit logs for proper service level management) are being introduced in many Hospitals to cope with increasing levels of information quality and safety requirements, the standard maturity levels of hospital IT departments is still not enough to reach the level of frequent use of audit logs. This paper aims to address the issues related to the existence of AT in patient records, describe the Hospitals scenario and to produce recommendations. Representatives from four hospitals were interviewed regarding the use of AT in their Hospital IS. Very few AT are known to exist in these hospitals (average of 1 per hospital in an estimate of 21 existing IS). CIOs should to be much more concerned with the existence and maintenance of AT. Recommendations include server clock synchronization and using advanced log visualization tools.
- Published
- 2011
49. Control of allergic rhinitis and asthma test--a formal approach to the development of a measuring tool.
- Author
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Nogueira-Silva L, Martins SV, Cruz-Correia R, Azevedo LF, Morais-Almeida M, Bugalho-Almeida A, Vaz M, Costa-Pereira A, and Fonseca JA
- Subjects
- Adult, Aged, Consensus, Feasibility Studies, Female, Humans, Male, Middle Aged, Portugal, Young Adult, Asthma diagnosis, Asthma therapy, Rhinitis, Allergic, Perennial diagnosis, Rhinitis, Allergic, Perennial therapy, Rhinitis, Allergic, Seasonal diagnosis, Rhinitis, Allergic, Seasonal therapy, Surveys and Questionnaires
- Abstract
Background: The concurrent management of allergic rhinitis and asthma (ARA) has been recommended by Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines. However, a tool capable of assessing simultaneously the control of upper and lower airways diseases is lacking., Aim: To describe the studies conducted to design the control of ARA test (CARAT) questionnaire., Methods: We performed a literature review to generate a list of potentially important items for the assessment of control of ARA. A formal consensus development process, that used an innovative web-based application, was designed - 111 experts in ARA and 60 patients participated. At the final consensus meeting, 25 primary and secondary care physicians formulated the questions and response options. A qualitative feasibility study (n = 31 patients) was conducted to evaluate the comprehensibility of the questionnaire while testing two different designs., Results: Thirty-four potentially important items were identified. All the steps of the consensus process were completed in 2.5 months. The opinions of experts and patients lead to the formulation of 17 questions. At the feasibility study the instructions and wording problems were corrected and a semi-tabular format was chosen., Conclusion: A tool to measure the control of allergic rhinitis and asthma was developed using a comprehensive set of methodological steps ensuring the design quality and the face and content validity. Additional validation studies to assess the psychometric properties of the questionnaire have started.
- Published
- 2009
- Full Text
- View/download PDF
50. Remote diagnosis of children dental problems based on non-invasive photographs - a valid proceeding?
- Author
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Amável R, Cruz-Correia R, and Frias-Bulhosa J
- Subjects
- Child, Preschool, Humans, Dental Care for Children, Diagnosis, Differential, Photography, Remote Consultation
- Abstract
Telemedicine models using commercially available technology have enabled high-quality illness care in paediatric primary care settings and markedly improved access. This fact should be explored in Pediatric Dentistry, considering that dental problems are very common in children at pre-school age and it becomes important to screen them as early as possible in order to promote the appropriate treatment. In this sense, we aim to know how telemedicine, or more specifically, teledentistry, could help on this process, evaluating the validity of children dental problems remote diagnosis based on non-invasive photographs, using accessible and low-cost technologies. Three photographs were taken for each of 66 children to be remotely analyzed by four dentists. Each dentist filled a web-based questionnaire for each child. The same children had a traditional in-person dental consultation that is used as a gold standard in this study. The results show sensitivity between 94% and 100% and specificity between 52% and 100%. The positive predictive value was between 67% and 100% and the negative predictive value between 94% and 100%. These results suggest that remote diagnosis of children dental problems based on non-invasive photographs constitute a valid resource when we pretend to exclude referred children to a dentist for treatment of dental problems, but further studies should be carried out to increase the validity of this proceeding to referring children for the same treatment.
- Published
- 2009
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