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Primordial odontogenic tumor (POT) is a rare, mixed odontogenic neoplasm composed of spindled and stellate-shaped cells in myxoid stroma resembling dental papilla, surfaced by cuboidal-to-columnar odontogenic epithelium. Most POTs present in the posterior mandible as a well-demarcated radiolucency associated with a developing tooth in children and adolescents. POT is treated conservatively with no recurrences documented to-date. To describe the clinicopathological features of a recurrent POT. A 19-year-old female presented with an asymptomatic swelling, and panoramic radiograph revealed a multiloculated radiolucency in the mandibular body and ramus, with buccal and lingual perforation. The tumor was composed of plump spindle and stellate cells in a delicately collagenous and myxoid stroma, surfaced by columnar epithelial cells with reverse nuclear polarization. There was extensive epithelial proliferation forming invaginations within the tumor mass and organoid/enamel organ-like structures with enameloid-like deposits, dentinoid, and dystrophic calcifications. This was similar to the POT that had been excised four years prior from the same location. The patient underwent hemi-mandibulectomy and currently is free of disease at a thirteen-month follow-up. This report describes the first recurrent POT exhibiting extensive epithelial proliferation.

International audience; The assessment of the date of death (DOD) of animals found in archaeological sites provides insights into the exploitation of their environment by ancient mobile and sedentary populations. In an attempt to overcome the limitations of the traditional methods, we determine the DOD of domestic caprines using sequential oxygen isotope analysis of developing tooth enamel. We built a reference set composed of developing molars from 14 modern sheep and goats from Western and Central Mongolia with known DOD. The teeth were sequentially sampled, and δ 18 O sequences were modelled using a cosine function in order to position the lowermost δ 18 O value (δ f) within the annual cycle. We found that δ f values are strongly linearly correlated with the DOD (R 2 ¼ 0.88), allowing the use of this regression to estimate the DOD with a precision of about �25 d (1σ). This method was applied to determine the DOD of caprines found in two graves in the Xiongnu necropolis of Egiin Gol, Mongolia. We determined a slaughter date of late July and late September for the two graves, respectively, suggesting that burial occurred during the warm season. By combining this information with age at death assessed using tooth eruption stages and tooth wear patterns, we were also able to determine that caprine birth occurred mostly in April and was strongly controlled within this seasonal window by the herders, much like in Mongolia today.

Aim This study aimed to investigate salivary concentrations of Streptococcus mutans (S. mutans) and some Lactobacilli, and plaque index (PI) in patients wearing fixed versus removable orthodontic appliances. Methods A sample of 90 orthodontic patients (56 males and 34 females) was included in the study: 30 subjects (aged 21.5±1.5 years) were treated with removable clear aligners (CA), while for other 30 cases (aged 23.3±1.6 years) a fixed multibrackets appliance (MB) were utilized, and 30 patients (aged 18.2 ±1.5 years) wearied a removable positioner (RP). Salivary concentrations of S. mutans and Lactobacilli and PI were evaluated prior to start of the orthodontic treatment, after 3 months and 6 months. Results After 6 months, 40% of MB patients (12 subjects over 30) showed a concentration of S. mutans associated to high risk of developing tooth decay (CFU/ml>105), differently from participants wearing removable appliances (odds ratio = 5.05; 95% C.I. = 1.72‐14.78; chi‐square = 9.64; p = 0.0019). The same trens was observed for the concentration of Lactobacilli (odds ratio = 4.33; 95% C.I. = 1.53‐12.3; chi‐square = 8.229; p = 0.004). In addition, over the duration of the study, CA patients maintained PI at 0 level, while MB patients experienced a statistically significant increasing trend of PI over time, and their PI became clinically/statistically relevant after 6 months, respect to CA and RP patients. Conclusions Comparing all the data, while, after 6 months, only about 10% of CA patients and 13.3% of RP patients achieved a microbial colonization which may lead to high risk of caries development, about 40% of MB patients ‐ and 20% after 3 months ‐ showed a high level of vulnerability to developing caries, which require additional strategies for plaque control and microbial colonization to be employed.

Mandible is one of the commonly fractured bone in children during maxillofacial trauma. These factures are usually managed conservatively but sometimes require open reduction and internal fixation (ORIF). Management of mandibular fracture in children is influenced by the presence of developing permanent tooth buds, minimal anchorage from primary teeth and facial growth and development. Although, there have been technical and material advancements with ORIF, it is still associated with complications related to growth and damage to developing teeth. This case report describes a case of mandibular parasymphyseal fracture managed successfully with open reduction and internal fixation using a miniplate and a consequent cessation of root growth and eruption failure of a mandibular canine present in the fixation area.

The mandibular second premolar is highly variable developmentally. Agenesis, abnormal tooth germ position, distal inclination of the developing tooth, and impaction are among the reported developmental anomalies. Detection of pathologic lesions associated with an impacted tooth usually requires removal of the tooth and the lesion. The purpose of the present report was to describe the radiographic and histopathologic features of a case of pericoronal radiolucency associated with an impacted mandibular premolar tooth.

Amongst the cysts of the jaw dentigerous cyst (DC) is one of the most prevalent types of odontogenic cysts, which is associated with the crown of an unerupted or developing tooth. DC is more commonly seen with mandibular third molar and maxillary canine and rarely other teeth are involved. These cysts seldom associate with supernumerary teeth. The purpose of this article is to describe a case of large dentigerous cyst associated with supernumerary teeth and an ectopic canine, which is a rare presentation along with its management.Key words: Dentigerous cyst, ectopic teeth, supernumerary teeth

Cleft lip and palate (CLP) is the most common craniofacial abnormality and the fourth most common birth defect in Singapore. Many reports suggest that CLP children have delayed dental development and asymmetrical timing of tooth-pair formation. The aim of this study was to investigate the timing of development of permanent teeth in unilateral CLP (UCLP) children and to compare the findings with non-CLP children in Singapore. A total of 60 UCLP children aged between 5 and 9 years (mean 6.64 ± 0.90 years) and a non-CLP control group matched for age, gender, and race were investigated and compared. Dental records and radiographs were studied and the dental maturation was determined using the Demirjian's method (1973). The dental maturation of UCLP children were delayed compared with non-CLP children by a mean of 0.55 ± 0.75 years and the delay was statistically significant (P < 0.001). The UCLP group also had significantly higher risk of asymmetrically developing tooth pairs than the control group (P < 0.001). The most commonly delayed tooth in development was the maxillary cleft-sided lateral incisor. In conclusion, the UCLP children in Singapore demonstrated delayed dental maturation and a higher occurrence of asymmetrical tooth-pair formation than the non-CLP children.