Search

Your search keyword '"Di Fiore, Juliann M"' showing total 121 results
Start Over Author "Di Fiore, Juliann M" Language english
121 results on '"Di Fiore, Juliann M"'

3. Apnea, Intermittent Hypoxemia, and Bradycardia Events Predict Late-Onset Sepsis in Infants Born Extremely Preterm

Author

Krahn, Katy N., Zimmet, Amanda M., Hopkins, Bradley S., Lonergan, Erin K., Rand, Casey M., Zadell, Arlene, Nakhmani, Arie, Carlo, Waldemar A., Laney, Deborah, Travers, Colm P., Vanbuskirk, Silvia, D’Ugard, Carmen, Aguilar, Ana Cecilia, Schott, Alini, Hoffmann, Julie, Linneman, Laura, Kausch, Sherry L., Lake, Douglas E., Di Fiore, Juliann M., Weese-Mayer, Debra E., Claure, Nelson, Ambalavanan, Namasivayam, Vesoulis, Zachary A., Fairchild, Karen D., Dennery, Phyllis A., Hibbs, Anna Maria, Martin, Richard J., Indic, Premananda, Bancalari, Eduardo, Hamvas, Aaron, Kemp, James S., Carroll, John L., Moorman, J. Randall, and Sullivan, Brynne A.

Published
2024
Full Text
View/download PDF

7. Limitations of Conventional Magnetic Resonance Imaging as a Predictor of Death or Disability Following Neonatal Hypoxic–Ischemic Encephalopathy in the Late Hypothermia Trial

Author

Caplan, Michael S., Polin, Richard A., Keszler, Martin, Oh, William, Vohr, Betty R., McGowan, Elizabeth C., Alksninis, Barbara, Basso, Kristin, Bliss, Joseph, Bishop, Carmena, Burke, Robert T., Cashore, William, Caskey, Melinda, Gingras, Dan, Guerina, Nicholas, Johnson, Katharine, Keszler, Mary Lenore, Knoll, Andrea M., Leach, Theresa M., Leonard, Martha R., Little, Emilee, Stephens, Bonnie E., Vieira, Elisa, Watson, Victoria E., Hibbs, Anna Maria, Wilson-Costello, Deanne E., Newman, Nancy S., Batton, Beau, Bhola, Monika, Di Fiore, Juliann M., Friedman, Harriet G., Siner, Bonnie S., Stork, Eileen K., Yalcinkaya, Gulgun, Zadell, Arlene, Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Knutson, Allison, Schibler, Kurt, Yolton, Kimberly, Grisby, Cathy, Gratton, Teresa L., Merhar, Stephanie, Wuertz, Sandra, Cotten, C. Michael, Fisher, Kimberley A., Grimes, Sandra, Finkle, Joanne, Goldstein, Ricki F., Gustafson, Kathryn E., Malcolm, William F., Ashley, Patricia L., Auten, Kathy J., Lohmeyer, Melody B., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Clark, Cindy, Warner, Diane D., Wereszcsak, Janice, Aliaga, Sofia, Carlton, David P., Stoll, Barbara J., Hale, Ellen C., Loggins, Yvonne, Bottcher, Diane I., Mackie, Colleen, LaRossa, Maureen Mulligan, Adams-Chapman, Ira, Wineski, Lynn C., Carter, Sheena L., Higgins, Rosemary D., Archer, Stephanie Wilson, Harmon, Heidi M., Papile, Lu-Ann, Dusick, Anna M., Gunn, Susan, Herron, Dianne E., Hines, Abbey C., Kardatzke, Darlene, Lytle, Carolyn, Minnich, Heike M., Richard, Leslie, Smiley, Lucy C., Wilson, Leslie Dawn, Kennedy, Kathleen A., Allain, Elizabeth, Mason, Carrie M., Arldt-McAlister, Julie, Burson, Katrina, Dempsey, Allison G., Duncan, Andrea F., Evans, Patricia W., Garcia, Carmen, Green, Charles E., Jimenez, Margarita, John, Janice, Jones, Patrick M., Lillie, M. Layne, Martin, Karen, Martin, Sara C., McDavid, Georgia E., McKee, Shannon, Pierce Tate, Patti L., Rodgers, Shawna, Siddiki, Saba Khan, Sperry, Daniel K., Wright, Sharon L., Sánchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Fortney, Christine A., Grothause, Jennifer L., Wallace, Dennis, Gantz, Marie G., Zaterka-Baxter, Kristin M., Crawford, Margaret M., McDonald, Scott A., Newman, Jamie E., O'Donnell Auman, Jeanette, Petrie Huitema, Carolyn M., Pickett, James W., II, Yost, Patricia, Van Meurs, Krisa P., Stevenson, David K., Ball, M. Bethany, Bentley, Barbara, Chock, Valerie Y., Bruno, Elizabeth F., Davis, Alexis S., DeAnda, Maria Elena, DeBattista, Anne M., Earhart, Beth, Huffman, Lynne C., Kohn, Jean G., Krueger, Casey E., Proud, Melinda S., Rhine, William D., St. John, Nicholas H., Taylor, Heather, Weiss, Hali E., Carlo, Waldemar A., Peralta-Carcelen, Myriam, Collins, Monica V., Cosby, Shirley S., Phillips, Vivien A., Rector, Richard V., Whitley, Sally, Colaizy, Tarah T., Brumbaugh, Jane E., Johnson, Karen J., Eastman, Diane L., Acarregui, Michael J., Walker, Jacky R., Goeke, Claire A., Klein, Jonathan M., Krutzfield, Nancy J., Segar, Jeffrey L., Dagle, John M., Lindower, Julie B., McElroy, Steven J., Rabe, Glenda K., Roghair, Robert D., Meyer, Lauritz R., Ellsbury, Dan L., Campbell, Donia B., Murphy, Cary R., Bhavsar, Vipinchandra, Ohls, Robin K., Lacy, Conra Backstrom, Beauman, Sandra Sundquist, Brown, Sandra, Fernandez, Erika, Duncan, Andrea Freeman, Fuller, Janell, Kuan, Elizabeth, Lowe, Jean R., Schmidt, Barbara, Kirpalani, Haresh, DeMauro, Sara B., Dysart, Kevin C., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara M., Bernbaum, Judy C., Gerdes, Marsha, Hurt, Hallam, D'Angio, Carl, Lakshminrusimha, Satyan, Laroia, Nirupama, Myers, Gary J., Yost, Kelley, Guilford, Stephanie, Jensen, Rosemary L., Wynn, Karen, Farooq, Osman, Reynolds, Anne Marie, Wadkins, Holly I.M., Williams, Ashley, Merzbach, Joan, Conway, Patrick, Bowman, Melissa, Hartley-McAndrew, Michele, Zorn, William, Fallone, Cait, Binion, Kyle, Orme, Constance, Scorsone, Ann Marie, Brion, Luc P., Chalak, Lina F., Heyne, Roy J., Chen, Lijun, Vasil, Diana M., Adams, Sally S., Boatman, Catherine Twell, Guzman, Alicia, Heyne, Elizabeth T., Lee, Lizette E., Leps, Melissa H., Madden, Linda A., Miller, Nancy A., Ramon, Emma, Yoder, Bradley A., Osborne, Karen A., Spencer, Cynthia, Steele, R. Edison, Steffen, Mike, Strong, Karena, Weaver-Lewis, Kimberlee, Baker, Shawna, Winter, Sarah, Bird, Karie, Burnett, Jill, Sood, Beena G., Bara, Rebecca, Childs, Kirsten, De Jesus, Lilia C., Panaitescu, Bogdan, Chawla, Sanjay M.D., Prentice, Jeannette E., Goldston, Laura A., Woldt, Eunice Hinz, Natarajan, Girija, Bajaj, Monika, Barks, John, Christensen, Mary, Wiggins, Stephanie A., Laptook, Abbot R., Shankaran, Seetha, Barnes, Patrick, Rollins, Nancy, Do, Barbara T., Parikh, Nehal A., Hamrick, Shannon, Hintz, Susan R., Tyson, Jon E., Bell, Edward F., Ambalavanan, Namasivayam, Goldberg, Ronald N., Pappas, Athina, Huitema, Carolyn, Pedroza, Claudia, Chaudhary, Aasma S., Hensman, Angelita M., Das, Abhik, Wyckoff, Myra, Khan, Amir, Walsh, Michelle C., Watterberg, Kristi L., Faix, Roger, Truog, William, Guillet, Ronnie, Sokol, Gregory M., and Poindexter, Brenda B.

Published
2021
Full Text
View/download PDF

15. Pre-Vent: the prematurity-related ventilatory control study

Author

Dennery, Phyllis A., Di Fiore, Juliann M., Ambalavanan, Namasivayam, Bancalari, Eduardo, Carroll, John L., Claure, Nelson, Hamvas, Aaron, Hibbs, Anna Maria, Indic, Premananda, Kemp, James, Krahn, Katy N., Lake, Douglas, Laposky, Aaron, Martin, Richard J., Natarajan, Aruna, Rand, Casey, Schau, Molly, Weese-Mayer, Debra E., Zimmet, Amanda M., and Moorman, J. Randall

Published
2019
Full Text
View/download PDF

16. Patterns of Oxygenation, Mortality, and Growth Status in the Surfactant Positive Pressure and Oxygen Trial Cohort

Author

Jobe, Alan H., Caplan, Michael S., Polin, Richard A., Laptook, Abbot R., Oh, William, Hensman, Angelita M., Gingras, Dan, Barnett, Susan, Lillie, Sarah, Francis, Kim, Andrews, Dawn, Angela, Kristen, Fanaroff, Avroy A., Newman, Nancy S., Siner, Bonnie S., Zadell, Arlene, Schibler, Kurt, Donovan, Edward F., Bridges, Kate, Alexander, Barbara, Grisby, Cathy, Mersmann, Marcia Worley, Mincey, Holly L., Hessling, Jody, Goldberg, Ronald N., Cotten, C. Michael, Wallace, David K., Freedman, Sharon F., Auten, Kathy J., Fisher, Kimberly A., Foy, Katherine A., Stoll, Barbara J., Piazza, Anthony J., Buchter, Susie, Carlton, David P., Hutchinson, Amy K., Hale, Ellen C., Higgins, Rosemary D., Archer, Stephanie Wilson, Poindexter, Brenda B., Lemons, James A., Hamer, Faithe, Herron, Dianne E., Miller, Lucy C., Wilson, Leslie D., Berberich, Mary Anne, Blaisdell, Carol J., Gail, Dorothy B., Kiley, James P., Gantz, Marie G., Das, Abhik, Crawford, Margaret M., Hastings, Betty K., Irene, Amanda R., O'Donnell Auman, Jeanette, Huitema, Carolyn Petrie, Pickett, James W., II, Wallace, Dennis, Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Stevenson, David K., Ball, M. Bethany, Proud, Melinda S., Frantz, Ivan D., III, Fiascone, John M., Furey, Anne, MacKinnon, Brenda L., Nylen, Ellen, Ambalavanan, Namasivayam, Collins, Monica V., Cosby, Shirley S., Phillips, Vivien A., Rasmussen, Maynard R., Wozniak, Paul R., Rich, Wade, Arnell, Kathy, Bridge, Renee, Demetrio, Clarence, Bell, Edward F., Widness, John A., Klein, Jonathan M., Johnson, Karen J., Duara, Shahnaz, Everett-Thomas, Ruth, Watterberg, Kristi L., Ohls, Robin K., Rohr, Julie, Lacy, Conra Backstrom, Phelps, Dale L., Laroia, Nirupama, Markowitz, Gary David, Reubens, Linda J., Burnell, Erica, Sánchez, Pablo J., Rosenfeld, Charles R., Salhab, Walid A., Allen, James, Grau, Laura, Guzman, Alicia, Hensley, Gaynelle, Lepps, Melissa H., Martin, Melissa, Miller, Nancy A., Solis, Araceli, Vasil, Diana M, Wilder, Kerry, Kennedy, Kathleen A., Tyson, Jon E., Morris, Brenda H., Harris, Beverly Foley, Lis, Anna E., Martin, Sarah, McDavid, Georgia E., Tate, Patti L., Wright, Sharon L., Yoder, Bradley A., Faix, Roger G., Burnett, Jill, Jensen, Jennifer J., Osborne, Karen A., Spencer, Cynthia, Weaver-Lewis, Kimberlee, O'Shea, T. Michael, Peters, Nancy J., Shankaran, Seetha, Sood, Beena G., Bara, Rebecca, Billian, Elizabeth, Johnson, Mary, Ehrenkranz, Richard A., Narendran, Vivek, Bhandari, Vineet, Jacobs, Harris C., Cervone, Pat, Gettner, Patricia, Konstantino, Monica, Poulsen, JoAnn, Taft, Janet, Di Fiore, Juliann M., Martin, Richard J., Li, Hong, Morris, Nathan, Carlo, Waldemar A., Finer, Neil, and Walsh, Michele

Published
2017
Full Text
View/download PDF

17. Association between Intermittent Hypoxemia and NICU Length of Stay in Preterm Infants.

Author

Hibbs, Anna Maria, Chen, Zhengyi, Minich, Nori M., Martin, Richard J., Raffay, Thomas M., MacFarlane, Peter M., and Di Fiore, Juliann M.

Subjects
PREMATURE infants, OXYGEN saturation, HYPOXEMIA, GESTATIONAL age, INFANTS
Abstract

Introduction: Length of hospitalization varies widely in preterm infants and can be affected by multiple maternal and neonatal factors including respiratory instability. Therefore, we aimed to determine the association between postnatal intermittent hypoxemia (IH) and prolonged hospitalization. Methods: This prospective single-center cohort study followed infants born at <31 weeks of gestational age through 2 years corrected age with detailed oxygen saturation data captured from days 7 to 30 of age. Results: 51/164 (31%) of infants were discharged after 400/7 weeks of corrected gestational age (CGA). A greater average daily number of IH events (OR per 10 events/day 1.33 [95% CI 1.03–1.72]), duration of events (OR per minute 1.14 [1.07–1.21]), and percent time with oxygen saturation <80% (OR per percent 1.88 [1.25–2.85]) on days 7–30 of age were all significantly associated with prolonged hospitalization past 400/7 weeks CGA. In survival analyses, infants with a greater average daily number of IH events (HR per 10 events/day 0.89 [0.81–0.98]), percent time with oxygen saturation <80% (HR per percent 0.79 [0.67–0.94]), and duration of events (HR per minute 0.93 [0.91–0.95]) on days 7–30 of age all had significantly lower probability of earlier discharge. In addition, there was a significant interaction with gestational age; the association between IH and prolonged hospitalization was stronger in more mature infants (p = 0.024). Conclusions: Physiological instability on days 7–30 of age, as manifested by IH, is significantly associated with prolonged hospitalization. IH likely represents both a marker of initial severity of illness and the beginning of biological cascades, leading to prematurity-associated morbidities. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

21. Maturation of cardioventilatory physiological trajectories in extremely preterm infants.

Author

Weese-Mayer, Debra E., Di Fiore, Juliann M., Lake, Douglas E., Hibbs, Anna Maria, Claure, Nelson, Qiu, Jiaxing, Ambalavanan, Namasivayam, Bancalari, Eduardo, Kemp, James S., Zimmet, Amanda M., Carroll, John L., Martin, Richard J., Krahn, Katy N., Hamvas, Aaron, Ratcliffe, Sarah J., Krishnamurthi, Narayanan, Indic, Premananda, Dormishian, Alaleh, Dennery, Phyllis A., and Moorman, J. Randall

Published
2024
Full Text
View/download PDF

23. Contributors

Author

Abrams, Steven A., Ågren, Johan, Ahuja, Sanjay P., Arnold, Hope Elizabeth, Arruda, Janine, Attar, Mohammad A., Ballard, A. Rebecca, Bancalari, Eduardo H., Bass, Nancy, Bearer, Cynthia F., Benitz, William E., Benjamin, John T., Bensen, Rachel, Berlin, Sheila C., Bhola, Monika, Bhombal, Shazia, Biron-Shental, Tal, Bocks, Martin L., Boe, Brian A., Calkins, Kara L., Cannon, Bryan, Carlo, Waldemar A., Carr, Cara Beth, Carter, Brian S., Chuang, Janet, Citla-Sridhar, Divyaswathi, Cizmeci, Mehmet N., Clark, Reese H., Costantine, Maged M., Crowley, Moira A., Curtis, Sean N., Davis, Peter G., de la Cruz, Diomel, de Vries, Linda S., Desai, Ankita P., Devaskar, Sherin U., Di Fiore, Juliann M., Ding, Hilda, Dingeldein, Michael, Donn, Steven M., Egler, Rachel, Ehret, Danielle E.Y., El-Metwally, Dina E., Ellis, Kelstan Lynch, Enciso, Josephine M., Famuyide, Mobolaji, Fanaroff, Jonathan M., Ford, Stephanie M., Franck, Linda S., Friedman, Smadar Eventov, Friedman, Susan Hatters, Garg, Meena, Gheorghe, Ciprian P., Gielchinsky, Yuval, Gilmore, Allison, Glotzbecker, Michael P., Goldsmith, Jay P., Gonzalez, Blanca E., Gould, Jeffrey B., Gressens, Pierre, Griswold, Katherine, Groenendaal, Floris, Gross, Susan J., Gurevich, Polina, Gutmark-Little, Iris, Hackney, David N., Hamvas, Aaron, Hanson, Ryan, Hardesty, Christina K., Harijith, Anantha Krishnan, Haward, Marlyse F., Hellström, Ann, Hershkovich-Shporen, Calanit, Hibbs, Anna Maria, Hooven, Thomas Alexander, Horbar, Jeffrey D., Hornik, Chi D., Hoyt, McCallum R., Hudak, Mark L., Hüppi, Petra S., Inder, Terrie E., Jacquot, Cyril, Jain, Lucky, Janzen, Carla, Jeyabalan, Arun, Jobe, Alan H., Kallapur, Suhas G., Kapadia, Vishal, Kaplan, Michael, Katheria, Anup C., Kaufman, David A., Kayyal, Simon, Khalili, Ali Salar, Konczal, Laura L., Kumar, Vasantha H.S., Kuper-Sassé, Margaret, Kusuda, Satoshi, Lagoski, Megan, Lakshminrusimha, Satyan, Laventhal, Naomi T., Lazebnik, Noam, Lazebnik, Roee S., Lee, Hanmin, Lehtonen, Liisa, Letterio, John, Lim, Peter Paul C., Liu, Raymond W., Magann, Everett F., Maheshwari, Akhil, Mangurten, Henry H., Manzoni, Paolo, Martin, Camilia R., Masumoto, Kenichi, McClary, Jacquelyn D., Mistovich, R. Justin, Mitchell, Anna L., Mo, Yunchuan Delores, Molloy, Eleanor J., Mukherjee, Devashis, Murthy, Karna, Nadipuram, Santhosh M., Nakanishi, Hidehiko, Narendran, Vivek, Neu, Josef, Nguyen, Quang, Nock, Mary L., Novod, Kimberly, Shlomai, Noa Ofek, Ogundare, Matilda Olajumoke, Ohliger, Shelley, Olicker, Arielle L., Örge, Faruk H., Otteson, Todd D., Owen, Louise S., Owusu-Ansah, Amma, Ozcan, Tulin, Parsons, Kimberly V., Pateva, Irina, Patrinos, Mary Elaine, Payne, Allison H., Peleg, David, Peña, Michelle-Marie, Poindexter, Brenda B., Polin, Richard Alan, Prazad, Preetha A., Profit, Jochen, Raffay, Thomas M., Rajpal, Miriam Noble, Krishna Raju, Tonse Narayana, Randis, Tara M., Redline, Raymond W., Robbins, Nathaniel, Ryan, Rita M., Saad, Antonio, Saade, George, Salem, Zeina M., Savich, Renate D., Schmidt, Augusto F., Schwab, Marisa Eve, Sferra, Thomas J., Shah, Jay, Shinwell, Eric S., Sibley, Eric, Simmons, Pamela M., Simpson-Lavy, Yael, Sivakumar, Kothandam, Smith, Lois E.H., Snyder, Christopher S., Son-Hing, Jochen P., Srinivas, Ganga L., Steinhorn, Robin H., Stepanovich, Gretchen E., Stevenson, David K., Strainic, James, Sudhadevi, Tara, Sun, Ye, Taylor, Kaitlyn Hebert, Thompson, Shelby, Thomson-Salo, Frances, Tiosano, Dov, Tolia, Veeral Nalin, Tomei, Krystal, Travers, Colm P., Trembath, Andrea N., Huerta Urrutia, Verania Y., VanHeyst, Kristen, Vento, Maximo, Vogt, Beth A., Vohr, Betty R., Wade, Kelly C., Wambach, Jennifer A., Watanabe, Michiko, Webb, Jennifer, Weiner, Maya Ram, Wherrett, Diane Katherine, White, Robert, Wilder, Travis J., Wilson-Costello, Deanne E., Wong, Ronald J., Wyckoff, Myra H., Yildiz-Atar, Hilal, Yogev, Yariv, and Zhou, Xiaofei

Published
2025
Full Text
View/download PDF

24. Contributors

Author

Abman, Steven H., Bancalari, Eduardo H., Cheong, Jeanie L.Y., Claure, Nelson, Davis, Peter G., Fisher, Elizabeth R., Kluckow, Martin, Luca, Daniele De, Di Fiore, Juliann M., Doyle, Lex W., Hodgson, Kate A., Hooper, Stuart Brian, Hooven, Thomas Alexander, Jobe, Alan H., Kallapur, Suhas G., Keszler, Martin, Lakshminrusimha, Satyan, Manley, Brett J., Martin, Richard J., McEvoy, Cindy T., Mukerji, Amit, Ambalavanan, Namasivayam, Navarrete, Cristina T., Nelin, Leif D., Noori, Shahab, Panitch, Howard B., Dargaville, Peter A., Jensen, Erik A., Okpaise, Oluwateniayo O., Park, Won Soon, Polin, Richard A., Ruano, Rodrigo, Schmidt, Augusto F., Schmidt, Barbara, Sett, Arun, Steinhorn, Robin H., Swarr, Daniel T., Thebaud, Bernard, Tingay, David Gerald, Viscardi, Rose M., Weiner, Gary Marshall, Whitsett, Jeffrey A., Wyckoff, Myra H., and Young, Karen Cecile

Published
2025
Full Text
View/download PDF

26. Cardiorespiratory Monitoring Data to Predict Respiratory Outcomes in Extremely Preterm Infants.

Author

Ambalavanan, Namasivayam, Weese-Mayer, Debra E., Hibbs, Anna Maria, Claure, Nelson, Carroll, John L., Randall Moorman, J., Bancalari, Eduardo, Hamvas, Aaron, Martin, Richard J., Di Fiore, Juliann M., Indic, Premananda, Kemp, James S., Dormishian, Alaleh, Krahn, Katy N., Qiu, Jiaxing, Dennery, Phyllis A., Ratcliffe, Sarah J., Troendle, James F., and Lake, Douglas E.

Subjects
PREMATURE infants, BRONCHOPULMONARY dysplasia, OXYGEN saturation, BIRTH weight, ARTIFICIAL respiration
Abstract

Rationale: Immature control of breathing is associated with apnea, periodic breathing, intermittent hypoxemia, and bradycardia in extremely preterm infants. However, it is not clear if such events independently predict worse respiratory outcome. Objectives: To determine if analysis of cardiorespiratory monitoring data can predict unfavorable respiratory outcomes at 40 weeks postmenstrual age (PMA) and other outcomes, such as bronchopulmonary dysplasia at 36 weeks PMA. Methods: The Prematurity-related Ventilatory Control (PreVent) study was an observational multicenter prospective cohort study including infants born at,29 weeks of gestation with continuous cardiorespiratory monitoring. The primary outcome was either “favorable” (alive and previously discharged or inpatient and off respiratory medications/O2/support at 40 wk PMA) or “unfavorable” (either deceased or inpatient/previously discharged on respiratory medications/O2/support at 40 wk PMA). Measurements and Main Results: A total of 717 infants were evaluated (median birth weight, 850 g; gestation, 26.4 wk), 53.7% of whom had a favorable outcome and 46.3% of whom had an unfavorable outcome. Physiologic data predicted unfavorable outcome, with accuracy improving with advancing age (area under the curve, 0.79 at Day 7, 0.85 at Day 28 and 32 wk PMA). The physiologic variable that contributed most to prediction was intermittent hypoxemia with oxygen saturation as measured by pulse oximetry,90%. Models with clinical data alone or combining physiologic and clinical data also had good accuracy, with areas under the curve of 0.84–0.85 at Days 7 and 14 and 0.86–0.88 at Day 28 and 32 weeks PMA. Intermittent hypoxemia with oxygen saturation as measured by pulse oximetry,80% was the major physiologic predictor of severe bronchopulmonary dysplasia and death or mechanical ventilation at 40 weeks PMA. Conclusions: Physiologic data are independently associated with unfavorable respiratory outcome in extremely preterm infants. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

30. Apnea is not prolonged by acid gastroesophageal reflux in preterm infants

Author

Di Fiore, Juliann M., Arko, Marina, Whitehouse, Meghan, Kimball, Amy, and Martin, Richard J.

Subjects
Gastroesophageal reflux -- Health aspects, Apnea -- Risk factors, Infants (Premature) -- Health aspects
Abstract

Objective. To examine the temporal relationship between apnea and gastroesophageal reflux (GER) and to assess the effect of GER on apnea duration. Methods. A total of 119 preterm infants underwent 12-hour cardiorespiratory monitoring studies using respiratory inductance plethysmography, heart rate, oxygen saturation (Sa[O.sub.2]), and esophageal pH. The studies were scored for GER (pH Results. There were 6255 episodes of GER. Only 1% of GER episodes were associated with apnea [greater than or equal to] 15 seconds, and there was no difference in apnea rate before, during, or after GER. There was also no difference in rate of apnea [greater than or equal to] 10 seconds before versus during GER; however, there was a decrease in apnea rate immediately after GER. The presence of GER during apnea did not prolong apnea duration, and GER had no effect on the lowest Sa[O.sub.2] or heart rate during apnea. Conclusion. There is no evidence of a temporal relationship between acid-based GER and apnea in preterm infants. In addition, GER does not prolong apnea duration and does not exacerbate the resultant decrease in heart rate and Sa[O.sub.2]. Pediatrics 2005;116:1059-1063; apnea, gastroesophageal reflux, neonates. ABBREVIATIONS. GER, gastroesophageal reflux; Sa[O.sub.2], oxygen saturation; ANOVA, analysis of variance., Gastroesophageal reflux (GER) and apnea are 2 clinical events that both occur commonly in the premature infant population. Early studies have suggested a relationship between GER and apnea (1-4) in [...]

Published
2005

39. Apnea, Intermittent Hypoxemia, and Bradycardia Events Predict Late-Onset Sepsis in Infants Born Extremely Preterm.

Author

Kausch, Sherry L., Lake, Douglas E., Di Fiore, Juliann M., Weese-Mayer, Debra E., Claure, Nelson, Ambalavanan, Namasivayam, Vesoulis, Zachary A., Fairchild, Karen D., Dennery, Phyllis A., Hibbs, Anna Maria, Martin, Richard J., Indic, Premananda, Travers, Colm P., Bancalari, Eduardo, Hamvas, Aaron, Kemp, James S., Carroll, John L., Moorman, J. Randall, and Sullivan, Brynne A.

Published
2024
Full Text
View/download PDF

41. The Relationship between Oxidative Stress, Intermittent Hypoxemia, and Hospital Duration in Moderate Preterm Infants.

Author

Shah, Vidhi P., Raffay, Thomas M., Martin, Richard J., Vento, Máximo, Sánchez-Illana, Ángel, Piñeiro-Ramos, José David, Kuligowski, Julia, and Di Fiore, Juliann M.

Subjects
PREMATURE infants, OXIDATIVE stress, FATTY acid oxidation, HYPOXEMIA, UNSATURATED fatty acids
Abstract

Introduction: Lipid peroxidation products are present following oxidation of polyunsaturated fatty acids in the eye, brain, and various cell membranes. Elevated levels of lipid peroxidation products and increased intermittent hypoxemia (IH) events have been associated with adverse outcomes in extremely preterm infants. The moderate preterm newborn has a still-developing oxidant defense system and immature respiratory control, but little is known about lipid peroxidation levels and IH in this larger and more common preterm population. Objective: To determine the association between oxidative stress and IH in moderate preterm infants. Method: Oxygen saturation was continuously monitored in 51 moderate preterm infants (i.e., 31 + 0/7 to 33 + 6/7 weeks' gestation). Urine samples were collected at the end of the first and second weeks of life. Samples were analyzed for total lipid peroxidation products (neurofurans, isofurans, neuroprostanes, isoprostanes, and di-homo-isofurans). Result: At week 1, there was a correlation between increased IH frequency and neurofurans (p < 0.04) and di-homo-isofurans (p < 0.003). At week 2, there was no correlation between IH and lipid peroxidation markers. Ele-vations in neurofurans, isofurans, neuroprostanes, and di-homo-isofurans in the first and/or second week of life were associated with a longer stay in hospital. Conclusion: Elevations in lipid peroxidation biomarkers in moderate preterm infants during their first weeks of life are associated with a higher frequency of IH and prolonged hospitalization. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

44. Prematurity and postnatal alterations in intermittent hypoxaemia.

Author

Di Fiore, Juliann M, Shah, Vidhi, Patwardhan, Abhijit, Sattar, Abdus, Wang, Shengxuan, Raffay, Thomas, Martin, Richard J, and Abu Jawdeh, Elie G

Subjects
PREMATURE infant diseases, RESEARCH, TIME, RESEARCH methodology, GESTATIONAL age, RETROSPECTIVE studies, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, RESEARCH funding
Abstract

Intermittent hypoxaemia (IH) events are well described in extremely preterm infants, but the occurrence of IH patterns in more mature preterm infants remains unclear. The objective of this study was to characterise the effect of gestational age on early postnatal patterns of IH in extremely (<28 weeks), very (28-<32 weeks) and moderately (32-<34 weeks) preterm infants. As expected, extremely preterm infants had a significantly higher frequency of IH events of longer durations and greater time with hypoxaemia versus very and moderately preterm infants. In addition, the postnatal decrease in IH duration was comparable in the very and moderately preterm infants. This progression of IH events should assist clinicians and families in managing expectations for resolution of IH events during early postnatal life. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

45. Contributors

Author

Abman, Steven H., Ambalavanan, Namasivayam, Askie, Lisa M., Bancalari, Eduardo, Bhandari, Vineet, Carlo, Waldemar A., Cheong, Jeanie L.Y., Claure, Nelson, Dargaville, Peter A., Davis, Peter G., Di Fiore, Juliann M., Doyle, Lex W., Hooper, Stuart B., Hooven, Thomas A., Jobe, Alan H., Kallapur, Suhas G., Keszler, Martin, Kluckow, Martin, Lal, Charitharth Vivek, Laughon, Matthew M., Manley, Brett J., Martin, Richard J., Nelin, Leif D., Noori, Shahab, Panitch, Howard B., Park, Won Soon, Polin, Richard A., Savani, Rashmin C., Shah, Vidhi P., Sosenko, Ilene R.S., Steinhorn, Robin H., Thébaud, Bernard, Viscardi, Rose M., Weiner, Gary M., Wu, Shu, Wyckoff, Myra H., Yoder, Bradley A., and Young, Karen C.

Published
2019
Full Text
View/download PDF

46. Contributors

Author

Abrams, Steven A., Agren, Johan, Al Remeithi, Sareea, Arnold, James E., Ashwath, Ravi, Bajaj, Komal, Baley, Jill E., Ballard, A. Rebecca, Bancalari, Eduardo H., Bansal, Manish, Bass, Nancy, Bearer, Cynthia F., Benitz, William E., Benjamin, John T., Blickstein, Isaac, Calkins, Kara L., Cannon, Bryan, Caplan, Michael, Carlo, Waldemar A., Chemlinsky, Gisela, Chuang, Janet, Cohen, Alan R., Crowley, Moira A., Dahlke, Joshua D., Davis, Peter, de Vries, Linda S., Dell, Katherine MacRae, Devaskar, Sherin U., Di Fiore, Juliann M., Diab, Yaser, Dobbs, Katherine, Donn, Steven M., Dubil, Elizabeth A., Ehrenkranz, Richard A., Falck, Alison J., Fanaroff, Avroy A., Fanaroff, Jonathan M., Fasano, Ross M., Friedman, Smadar, Garg, Meena, Gilmore, Allison, Goldsmith, Jay P., Gonzalez, Blanca E., Gould, Jeffrey B., Gressens, Pierre, Grigorian, Florin, Groenendaal, Floris, Gross, Susan J., Gurram, Bhaskar, Gutmark-Little, Iris, Hackney, David N., Halamek, Louis P., Hamvas, Aaron, Friedman, Susan Hatters, Hazan, Yenon, Hellström, Anne, Hibbs, Anna Maria, Hill, James Adam, Hintz, Susan R., Hirose, Shinjiro, Hoath, Steven B., Horbar, Jeffrey D., Hoyt, McCallum R., Hudak, Mark L., Hüppi, Petra S., Iqbal, Corey W., Jain, Lucky, Jeyabalan, Arun, Jobe, Alan H., Judge, Nancy E., Kallapur, Suhas G., Kaplan, Michael, Kaufman, David A., Kennedy, Kathleen A., Kouretas, Peter C., Kovalenko, Oleg, Larson-Nath, Catherine, Lazebnik, Noam, Lee, Hanmin, Lee, Henry C., Lehtonen, Liisa, Leonard, Ethan G., Lissauer, Tom, Liu, Raymond W., Lopez, Suzanne M., Lotze, Timothy E., Luban, Naomi L.C., Luchtman-Jones, Lori, Magann, Everett F., Maheshwari, Akhil, Mangurten, Henry H., Manzoni, Paolo, Markham, Kara Beth, Martin, Gilbert I., Martinez-Rios, Claudia, Maughan, Matthew J., McClary, Jacquelyn D., Mezu-Ndubuisi, Olachi J., Miller, Geoffrey, Mitchell, Anna L., Molteni, Richard, Mooney, Sandra M., Morley, Colin J., Morrison, Stuart C., Narang, Anil, Narendran, Vivek, Nock, Mary L., Örge, Faruk H., Otteson, Todd D., Owen, Louise, Pages-Arroyo, Elaine Marie, Parikh, Aditi S., Parry, Robert L., Patrinos, Mary Elaine, Payne, Allison H., Pearlman, Stephen A., Perlman, Sharon, Poindexter, Brenda B., Polin, Richard, Prazad, Preetha A., Profit, Jochen, Puppala, Bhagya L., Raju, Tonse N.K., Ramachandrappa, Ashwin, Randis, Tara M., Redline, Raymond W., Flidel Rimon, Orna, Robinson, Shenandoah, Rose, Susan R., Said, Miriam, Scher, Mark S., Shinwell, Eric S., Sibley, Eric, Sinha, Sunil K., Smith, Lois E.H., Snyder, Christopher S., Son-Hing, Jochen P., Steinhorn, Robin H., Stevenson, David K., Stork, Eileen K., Stork, John E., Strainic, James, Sun, Ye, te Pas, Arjan B., Thompson, George H., Thomson-Salo, Frances, Tiosano, Dov, Topf-Olivestone, Chani, Trembath, Andrea N., Turbow, Robert, Tyson, Jon E., Vento, Maximo, Vidyasagar, Dharmapuri, Vogt, Beth A., Vohr, Betty, Wade, Kelly C., Walsh, Michele C., Wambach, Jennifer A., Watanabe, Michiko, Weinert, Dayna M., Wherrett, Diane Katherine, White, Robert D., Wikenheiser, Jamie, Wilson-Costello, Deanne E., Wong, Ronald J., Wyckoff, Myra, and Zinn, Arthur B.

Published
2015
Full Text
View/download PDF

47. The Effect of Continuous Positive Airway Pressure in a Mouse Model of Hyperoxic Neonatal Lung Injury.

Author

Reyburn, Brent, Di Fiore, Juliann M., Raffay, Thomas, Martin, Richard J., Prakash, Y.S., Jafri, anjum, and MacFarlane, Peter M.

Subjects
*NEONATAL diseases, *CONTINUOUS positive airway pressure, *LUNG injuries, *BRONCHOPULMONARY dysplasia, *OXYGEN therapy, *THERAPEUTICS
Abstract

Background: Continuous positive airway pressure (CPAP) and supplemental oxygen have become the mainstay of neonatal respiratory support in preterm infants. Although oxygen therapy is associated with respiratory morbidities including bronchopulmonary dysplasia (BPD), the long-term effects of CPAP on lung function are largely unknown. We used a hyperoxia-induced mouse model of BPD to explore the effects of daily CPAP in the first week of life on later respiratory system mechanics. Objective: We wanted to test the hypothesis that daily CPAP in a newborn-mouse model of BPD improves longer-term respiratory mechanics. Methods: Mouse pups from C57BL/6 pregnant dams were exposed to room air (RA) or hyperoxia (50% O2, 24 h/day) for the first postnatal week with or without exposure to daily CPAP (6 cm H2O, 3 h/day). Respiratory system resistance (Rrs) and compliance (Crs) were measured following a subsequent 2-week period of RA recovery. Additional measurements included radial alveolar and macrophage counts. Results: Mice exposed to hyperoxia had significantly elevated Rrs, decreased Crs, reduced alveolarization and increased macrophage counts at 3 weeks when compared to RA-treated mice. Daily CPAP treatment significantly improved Rrs, Crs and alveolarization and decreased lung macrophage infiltration in the hyperoxia-exposed pups. Conclusions: We have demonstrated that daily CPAP had a longer-term benefit on baseline respiratory system mechanics in a neonatal mouse model of BPD. We speculate that this beneficial effect of CPAP was the consequence of a decrease in the inflammatory response and resultant alveolar injury associated with hyperoxic lung injury in newborns. © 2015 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

48. Intermittent Hypoxemia and Bronchopulmonary Dysplasia: Manifestations of Immature Respiratory Control and the Preterm Lung.

Author

Di Fiore, Juliann M., Martin, Richard J., and Raffay, Thomas M.

Subjects
BRONCHOPULMONARY dysplasia, CARDIOVASCULAR agents, PREMATURE labor, RESPIRATORY therapy, HYPOXEMIA
Abstract

An editorial is presented on Bronchopulmonary dysplasia (BPD) redefined in diagnosis, causalities, and therapies. Topics include chronic condition of parenchymal, airway, and cardiovascular pathology after preterm birth; and defined by the degree of respiratory therapy needed to prevent hypoxemia and death during the first weeks of life.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results