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164 results on '"Don, Creighton W."'

1. Association of ACEI/ARB and statin prescribing patterns with mortality after Transcatheter Aortic Valve Replacement (TAVR): Findings from real-world claims data

Author

Cubeddu, Robert J., Murphy, Shannon M.E., Asher, Craig R., Garcia, Santiago A., Granada, Juan F., Don, Creighton W., Patel, Sankalp, Albaghdadi, Mazen S., Cavalcante, João L., Coylewright, Megan, Hahn, Rebecca T., Genereux, Philippe, Yadav, Pradeep K., Thourani, Vinod H., and Leon, Martin B.

Published
2023
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2. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Author

Lawton, Jennifer S., Tamis-Holland, Jacqueline E., Bangalore, Sripal, Bates, Eric R., Beckie, Theresa M., Bischoff, James M., Bittl, John A., Cohen, Mauricio G., DiMaio, J. Michael, Don, Creighton W., Fremes, Stephen E., Gaudino, Mario F., Goldberger, Zachary D., Grant, Michael C., Jaswal, Jang B., Kurlansky, Paul A., Mehran, Roxana, Metkus, Thomas S., Jr., Nnacheta, Lorraine C., Rao, Sunil V., Sellke, Frank W., Sharma, Garima, Yong, Celina M., and Zwischenberger, Brittany A.

Published
2022
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3. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Author

Lawton, Jennifer S., Tamis-Holland, Jacqueline E., Bangalore, Sripal, Bates, Eric R., Beckie, Theresa M., Bischoff, James M., Bittl, John A., Cohen, Mauricio G., DiMaio, J. Michael, Don, Creighton W., Fremes, Stephen E., Gaudino, Mario F., Goldberger, Zachary D., Grant, Michael C., Jaswal, Jang B., Kurlansky, Paul A., Mehran, Roxana, Metkus, Thomas S., Jr., Nnacheta, Lorraine C., Rao, Sunil V., Sellke, Frank W., Sharma, Garima, Yong, Celina M., and Zwischenberger, Brittany A.

Published
2022
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4. Coronary ostial eccentricity in severe aortic stenosis: Guidance for BASILICA transcatheter leaflet laceration

Author

Komatsu, Ikki, Leipsic, Jonathon, Webb, John G., Blanke, Philipp, Mackensen, G. Burkhard, Don, Creighton W., McCabe, James M., Rumer, Christopher, Tan, Christina W., Levin, Dmitry B., Ramos, Mario, Aldea, Gabriel S., Reisman, Mark, Wijeysundera, Harindra C., Radhakrishnan, Sam, Sathananthan, Janarthanan, Piazza, Nicolo, Kornowski, Ran, and Dvir, Danny

Published
2020
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7. Mid-Term Outcomes of Transcatheter Aortic Valve Replacement in Extremely Large Annuli With Edwards SAPIEN 3 Valve

Author

Sengupta, Aditya, Zaid, Syed, Kamioka, Norihiko, Terre, Juan, Miyasaka, Masaki, Hirji, Sameer A., Hensey, Mark, Geloo, Nadim, Petrossian, George, Robinson, Newell, Sarin, Eric, Ryan, Liam, Yoon, Sung-Han, Tan, Christina W., Khalique, Omar K., Kodali, Susheel K., Kaneko, Tsuyoshi, Shah, Pinak B., Wong, S. Chiu, Salemi, Arash, Sharma, Kapil, Kozina, Joseph A., Szerlip, Molly A., Don, Creighton W., Gafoor, Sameer, Zhang, Ming, Newhart, Zachary, Kapadia, Samir R., Mick, Stephanie L., Krishnaswamy, Amar, Kini, Annapoorna, Ahmad, Hasan, Lansman, Steven L., Mack, Michael J., Webb, John G., Babaliaros, Vasilis, Thourani, Vinod H., Makkar, Raj R., Leon, Martin B., George, Isaac, and Tang, Gilbert H.L.

Published
2020
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9. Impact of Aortic Root Anatomy and Geometry on Paravalvular Leak in Transcatheter Aortic Valve Replacement With Extremely Large Annuli Using the Edwards SAPIEN 3 Valve

Author

Tang, Gilbert H.L., Zaid, Syed, George, Isaac, Khalique, Omar K., Abramowitz, Yigal, Maeno, Yoshio, Makkar, Raj R., Jilaihawi, Hasan, Kamioka, Norihiko, Thourani, Vinod H., Babaliaros, Vasilis, Webb, John G., Htun, Nay M., Attinger-Toller, Adrian, Ahmad, Hasan, Kaple, Ryan, Sharma, Kapil, Kozina, Joseph A., Kaneko, Tsuyoshi, Shah, Pinak, Hirji, Sameer A., Desai, Nimesh D., Anwaruddin, Saif, Jagasia, Dinesh, Herrmann, Howard C., Basra, Sukhdeep S., Szerlip, Molly A., Mack, Michael J., Mathur, Moses, Tan, Christina W., Don, Creighton W., Sharma, Rahul, Gafoor, Sameer, Zhang, Ming, Kapadia, Samir R., Mick, Stephanie L., Krishnaswamy, Amar, Amoroso, Nicholas, Salemi, Arash, Wong, S. Chiu, Kini, Annapoorna S., Rodés-Cabau, Josep, Leon, Martin B., and Kodali, Susheel K.

Published
2018
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10. Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates

Author

Liu, Yen-Wen, Chen, Billy, Yang, Xiulan, Fugate, James A, Kalucki, Faith A, Futakuchi-Tsuchida, Akiko, Couture, Larry, Vogel, Keith W, Astley, Clifford A, Baldessari, Audrey, Ogle, Jason, Don, Creighton W, Steinberg, Zachary L, Seslar, Stephen P, Tuck, Stephanie A, Tsuchida, Hiroshi, Naumova, Anna V, Dupras, Sarah K, Lyu, Milly S, Lee, James, Hailey, Dale W, Reinecke, Hans, Pabon, Lil, Fryer, Benjamin H, MacLellan, W Robb, Thies, R Scott, and Murry, Charles E

Published
2018
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13. It is time to be heard and understood: Readmission probably is not the outcome that matters among people with dementia considering percutaneous coronary intervention.

Author

Bernacki, Gwen M., Krishnaswami, Ashok, and Don, Creighton W.

Subjects
WELL-being, PERCUTANEOUS coronary intervention, PATIENT readmissions, CARDIOVASCULAR diseases, DEMENTIA, DECISION making, DELIRIUM, ACCIDENTAL falls, NON-ST elevated myocardial infarction
Abstract

This editorial comments on the article by Park et al. in this issue. [ABSTRACT FROM AUTHOR]

Published
2023
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15. Erratum: Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates

Author

Liu, Yen-Wen, Chen, Billy, Yang, Xiulan, Fugate, James A, Kalucki, Faith A, Futakuchi-Tsuchida, Akiko, Couture, Larry, Vogel, Keith W, Astley, Clifford A, Baldessari, Audrey, Ogle, Jason, Don, Creighton W, Steinberg, Zachary L, Seslar, Stephen P, Tuck, Stephanie A, Tsuchida, Hiroshi, Naumova, Anna V, Dupras, Sarah K, Lyu, Milly S, Lee, James, Hailey, Dale W, Reinecke, Hans, Pabon, Lil, Fryer, Benjamin H, MacLellan, W Robb, Thies, R Scott, and Murry, Charles E

Published
2018
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18. Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

Author

Chong, James J.H., Yang, Xiulan, Don, Creighton W., Minami, Elina, Liu, Yen-Wen, Weyers, Jill J., Mahoney, Jr., William M., Van Biber, Benjamin, Cook, Savannah M., Palpant, Nathan J., Gantz, Jay A., Fugate, James A., Muskheli, Veronica, Gough, G. Michael, Vogel, Keith W., Astley, Cliff A., Hotchkiss, Charlotte E., Baldessari, Audrey, Pabon, Lil, Reinecke, Hans, Gill, Edward A., Nelson, Veronica, Kiem, Hans-Peter, Laflamme, Michael A., and Murry, Charles E.

Subjects
Embryonic stem cells -- Research, Heart cells -- Research, Regeneration (Biology) -- Research, Stem cell research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Pluripotent stem cells provide a potential solution to current epidemic rates of heart failure (1) by providing human cardiomyocytes to support heart regeneration (2). Studies of human embryonic-stem-cell-derived cardiomyocytes (hESC-CMs) in small-animal models have shown favourable effects of this treatment (3-7). However, it remains unknown whether clinical-scale hESC-CM transplantation is feasible, safe or can provide sufficient myocardial regeneration. Here we show that hESC-CMs can be produced at a clinical scale (more than one billion cells per batch) and cryopreserved with good viability. Using a non-human primate model of myocardial ischaemia followed by reperfusion, we show that cryopreservation and intramyocardial delivery of one billion hESC-CMs generates extensive remuscularization of the infarcted heart. The hESC-CMs showed progressive but incomplete maturation over a 3-month period. Grafts were perfused by host vasculature, and electromechanical junctions between graft and host myocytes were present within 2 weeks of engraftment. Importantly, grafts showed regular calcium transients that were synchronized to the host electrocardiogram, indicating electromechanical coupling. In contrast to small-animal models (7),nonfatal ventricular arrhythmias were observed in hESC-CM-engrafted primates. Thus, hESC-CMs can remuscularize substantial amounts of the infarcted monkey heart. Comparable remuscularization of a human heart should be possible, but potential arrhythmic complications need to be overcome., Human pluripotent stem cells have indisputable cardiomyocyte-generating abilities and have been extensively investigated for repair of the injured heart (3,4,6,10). These stem cells are derived either from developing blastocytsts (human [...]

Published
2014

28. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Author

Lawton, Jennifer S. Chair, Tamis-Holland, Jacqueline E. FACC, FSCAI, Vice Chair, Bangalore, Sripal MHA, FACC, FSCAI, Bates, Eric R. FACC, FAHA, Beckie, Theresa M. FAHA, Bischoff, James M. MEd, Bittl, John A. FACC, FAHA, Cohen, Mauricio G. FACC, FSCAI, DiMaio, J. Michael, Don, Creighton W. FACC, Fremes, Stephen E. FACC, Gaudino, Mario F. FACC, FAHA, Goldberger, Zachary D. FACC, FAHA, Grant, Michael C. MSE, Jaswal, Jang B. MS, Kurlansky, Paul A. FACC, Mehran, Roxana FACC, Metkus, Thomas S. Jr FACC, Nnacheta, Lorraine C. DrPH,, and Rao, Sunil V. FACC

Published
2022
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29. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Author

Lawton, Jennifer S. Chair, Tamis-Holland, Jacqueline E. FACC, FSCAI, Vice Chair, Bangalore, Sripal MHA, FACC, FSCAI, Bates, Eric R. FACC, FAHA, Beckie, Theresa M. FAHA, Bischoff, James M. MEd, Bittl, John A. FACC, Cohen, Mauricio G. FACC, FSCAI, DiMaio, J. Michael, Don, Creighton W. FACC, Fremes, Stephen E. FACC, Gaudino, Mario F. FACC, FAHA, Goldberger, Zachary D. FACC, FAHA, Grant, Michael C. MSE, Jaswal, Jang B. MS, Kurlansky, Paul A. FACC, Mehran, Roxana FACC, Metkus, Thomas S. Jr FACC, Nnacheta, Lorraine C. DrPH,, and Rao, Sunil V. FACC

Published
2022
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35. Distribution of C‐arm projections in native and bioprosthetic aortic valves cusps: Implication for BASILICA procedures.

Author

Komatsu, Ikki, Tang, Gilbert H. L., Leipsic, Jonathon, Webb, John G., Blanke, Philipp, Mackensen, G. Burkhard, Kitamura, Mitsunobu, Wolak, Arik, Don, Creighton W., McCabe, James M., Rumer, Christopher, Tan, Christina W., Levin, Dmitry B., Ramos, Mario, Aldea, Gabriel S., Reisman, Mark, Wijeysundera, Harindra C., Radhakrishnan, Sam, Sathananthan, Janarthanan, and Piazza, Nicolo

Published
2021
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36. Imaging of Aortic Valve Cusps Using Commissural Alignment: Guidance for Transcatheter Leaflet Laceration With BASILICA.

Author

Komatsu, Ikki, Leipsic, Jonathon, Webb, John B., Blanke, Philipp, Mackensen, G. Burkhard, Don, Creighton W., McCabe, James M., Rumer, Christopher, Tan, Christina W., Levin, Dmitry B., Ramos, Mario, Aldea, Gabriel S., Reisman, Mark, Wijeysundera, Harindra C., Radhakrishnan, Sam, Sathananthan, Janarthanan, Piazza, Nicolo, Kornowski, Ran, and Dvir, Danny

Published
2019
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40. Temporal trends and practice variations in clopidogrel loading doses in patients with non-ST-elevation myocardial infarction, from the NCDR

Author

Don, Creighton W., Roe, Matthew T., Li, Shuang, Fraulo, Elizabeth, Pomerantsev, Eugene, Palacios, Igor, and Wiviott, Stephen D.

Subjects
Aged, 80 and over, Male, Ticlopidine, Myocardial Infarction, Middle Aged, Article, Clopidogrel, Treatment Outcome, Humans, Female, Registries, Practice Patterns, Physicians', Platelet Aggregation Inhibitors, Aged, Retrospective Studies
Abstract

A higher loading dose of clopidogrel achieves a more rapid and consistent degree of platelet inhibition than standard dosing, although the clinical benefit of higher doses has not been clearly established. The use of the different doses in clinical practice is not known. We evaluated the patient, procedural, and hospital characteristics associated clopidogrel loading doses given to patients with non-ST-segment elevation myocardial infarction (NSTEMI).The National Cardiovascular Data Registry ACTION Get With the Guidelines Registry was queried for patients with NSTEMI admitted from 2007 to 2008. Demographic, clinical, and procedural information were collected on standardized data forms. Patients were categorized according to the clopidogrel loading dose received. Temporal trends in the use of different doses were evaluated in quarterly time intervals.Between January 1, 2007, and December 31, 2008, the use of a 600-mg clopidogrel loading dose increased steadily from 36.4% to 45.5%, whereas the use of 300 mg decreased slightly from 40.1% to 37.1%. Patients loaded with clopidogrel before cardiac catheterization were more likely to receive 300 mg, whereas those receiving a loading dose at the time of catheterization more often received 600 mg. The temporal increase in the use of 600 mg clopidogrel loading doses was not explained by temporal changes in periprocedural loading, use of early invasive management of patients with NSTEMI, or use of antithrombotics or glycoprotein 2b/3a inhibitors.Higher loading dose clopidogrel increased between 2007 and 2008. Higher-dose clopidogrel was more frequently used in lower-risk patients undergoing an early invasive strategy and receiving periprocedural loading.

Published
2011

41. Catharsis: On the Art of Medicine

Author

Don, Creighton W.

Subjects
Catharsis: On the Art of Medicine (Book) -- Book reviews, Books -- Book reviews
Published
2007

45. The outcomes of transcatheter aortic valve replacement in a cohort of patients with end-stage renal disease.

Author

Szerlip, Molly, Kim, Rebeca J., Adeniyi, Tokunbo, Thourani, Vinod, Babaliaros, Vasilis, Bavaria, Joseph, Herrmann, Howard C., Anwaruddin, Saif, Makkar, Raj, Chakravarty, Tarun, Rovin, Joshua, Don, Creighton W., Miller, D. Craig, Baio, Kim, Walsh, Elizabeth, Katinic, Jasmina, Letterer, Rebecca, Trautman, Leigh, Herbert, Morley, and Farkas, Robert

Published
2016
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46. Outcomes in Nonagenarians Undergoing Transcatheter Aortic Valve Replacement in the PARTNER-I Trial.

Author

Thourani, Vinod H., Jensen, Hanna A., Babaliaros, Vasilis, Kodali, Susheel K., Rajeswaran, Jeevanantham, Ehrlinger, John, Blackstone, Eugene H., Suri, Rakesh M., Don, Creighton W., Aldea, Gabriel, Williams, Mathew R., Makkar, Raj, Svensson, Lars G., McCabe, James M., Dean, Larry S., Kapadia, Samir, Cohen, David J., Pichard, Augusto D., Szeto, Wilson Y., and Herrmann, Howard C.

Abstract

Background This study describes short-term and mid-term outcomes of nonagenarian patients undergoing transfemoral or transapical transcatheter aortic valve replacement (TAVR) in the Placement of Aortic Transcatheter Valve (PARTNER)-I trial. Methods From April 2007 to February 2012, 531 nonagenarians, mean age 93 ± 2.1 years, underwent TAVR with a balloon-expandable prosthesis in the PARTNER-I trial: 329 through transfemoral (TF-TAVR) and 202 transapical (TA-TAVR) access. Clinical events were adjudicated and echocardiographic results analyzed in a core laboratory. Quality of life (QoL) data were obtained up to 1 year post-TAVR. Time-varying all-cause mortality was referenced to that of an age-sex-race–matched US population. Results For TF-TAVR, post-procedure 30-day stroke risk was 3.6%; major adverse events occurred in 35% of patients; 30-day paravalvular leak was greater than moderate in 1.4%; median post-procedure length of stay (LOS) was 5 days. Thirty-day mortality was 4.0% and 3-year mortality 48% (44% for the matched population). By 6 months, most QoL measures had stabilized at a level considerably better than baseline, with Kansas City Cardiomyopathy Questionnaire (KCCQ) 72 ± 21. For TA-TAVR, post-procedure 30-day stroke risk was 2.0%; major adverse events 32%; 30-day paravalvular leak was greater than moderate in 0.61%; and median post-procedure LOS was 8 days. Thirty-day mortality was 12% and 3-year mortality 54% (42% for the matched population); KCCQ was 73 ± 23. Conclusions A TAVR can be performed in nonagenarians with acceptable short- and mid-term outcomes. Although TF- and TA-TAVR outcomes are not directly comparable, TA-TAVR appears to carry a higher risk of early death without a difference in intermediate-term mortality. Age alone should not preclude referral for TAVR in nonagenarians. [ABSTRACT FROM AUTHOR]

Published
2015
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