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Impaired liver metabolic function is related to mortality in severely malnourished children. Here the authors report a role for the tryptophan-NAD + pathway in reduced hepatic mitochondrial function and liver steatosis in a mouse model of severe malnutrition.

Knowledge work today is characterized by frequent interruptions. Digital distraction plays an increasingly important role in this work context as workers' behavior and emotional state online spills into work practices, causing stress and productivity loss. This article discusses solutions to digital distraction by advancing the concepts of mindful work and mindful technology. In doing so, it first critiques the design of prevalent productivity tools (i.e., “block-and-avoid tools”) that avoid the problem rather than remediating it. We argue that mindfulness is particularly applicable to handling digital distraction and propose a two-part framework for mindful work and mindful design through which workers can learn to work with technology — and their emotions — in more constructive ways. Lastly, we expand on our mindful work framework by proposing the concept of an intelligent personal assistant.

Necrotizing enterocolitis (NEC) is one of the most lethal gastrointestinal emergencies in neonates needing precision treatment. Here the authors show that remote ischemic conditioning is a non-invasive therapeutic method that enhances blood flow in the intestine, reduces damage, and improves NEC outcome.

Self-branding is crucial for online freelancers as they must constantly differentiate themselves from competitors on online labor platforms to ensure a viable stream of income. By analyzing 39 interviews with freelancers and clients on the online labor platform Upwork, we identify five key self-branding strategies: boosting a profile, showcasing skills, expanding presence, maintaining relationships with clients, and individualizing brand. These self-branding strategies are contextualized within Goffman's dramaturgical theory and through an affordances lens, showing immanent tensions. While online freelancers successfully leverage self-branding to improve their visibility on Upwork and beyond, the client perspective reveals a fine line between too little and too much self-branding. Online freelancers must brand themselves in visibility games when the game rules are largely opaque, riddled with uncertainty, and constantly evolving. We connect the findings to adjacent platform economy research and derive a self-branding as a performance framework. [ABSTRACT FROM AUTHOR]

We propose that regulation increases the demand for industry-expert auditors. We hypothesize that this increase in demand will be reflected in the degree of reliance investors place on financial information certified by industry-expert auditors. We evaluate the return-earnings relation for regulated banks that choose industry-expert and non-industry-expert auditors. By enhancing the credibility of the financial statements, industry-expert auditors potentially strengthen the link between earnings and returns even in a regulated environment. The results suggest that the choice of an expert-auditor favorably affects investor valuations of the banks used in the sample. Earnings explains more of the variation of returns when the earnings numbers are certified by expert versus non-expert auditors after controlling for the effects of regulatory attention., INTRODUCTION Regulation can modify the nature of auditing. Regulation provides auditors with additional roles, roles that are better fulfilled by auditors who specialize in developing and understanding the subtleties and [...]

Since computers are universally accepted in business today, the accounting classroom is the appropriate place to teach their use. A California high school accounting committee's recommendation led to the school's development of a computer processing program within the accounting department. The program's curriculum is described. (CT)