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Paper itself describes operation principles of mechanical ventilator, it's electronic and pneumatic solutions, as well as wide spectrum of advantages for patients that are coming with this technology. Special emphasis is placed on new technology in mechanical ventilation, where unlike before when nurses and doctors were constantly monitoring and adjusting O2 levels delivered to newborn / neonate by ventilator, automation of this process, using “The closed loop controller of inspired oxygen system (CLiO2), offers opportunity for better care of neonates. We will display methods where CLiO2 system noninvasively and continuously measures the oxygen level in a newborn’s blood using Masimo SET® Measure-Through Motion and Low Perfusion pulse oximetry technology to provide accurate and saturation of peripheral oxygen (SpO2) measurements, even under challenging clinical conditions. Paper descibes that the CLiO2 system processes blood oxygen saturation levels by a computer algorithm that then anticipates trends and modifies the amount of oxygen delivered. It will be shown how this system helps reduce complications associated with newborns needing mechanical ventilation and can free up time for clinicians to better care for some of their most vulnerable patients.

This paper describes the methods and principles of the analyses of blood gases using membrane electrode for measuring pH, pCO2, pO2 and reference electrode. Advantages and disadvantages of using this technology are shown on the basis of samples used on the actual device installed at the central laboratory of the Clinical Centre of University Sarajevo. Paper describes principles of operation and conditioning of electrodes, proper handling, calibration process through one or two points, the importance of replacing the electrode membrane, and the procedure for checking the quality and reliability of the measurements themselves.