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A 60-year-old woman was under investigation of dyspeptic symptoms. The upper gastrointestinal endoscopy showed a cystic subepithelial lesion in the second portion of the duodenum, measuring 8 mm in its longest diameter. The biopsy showed dilated Brunner’s gland lobular ducts with scattered stromal elements, what characterized a Brunner’s gland cyst. Brunner’s gland cyst should be included in the differential diagnosis of gastrointestinal bleeding, dyspepsia, gastroesophageal reflux disease (GERD), malabsorption syndrome, anemia, among others. The correct nomenclature is important to facilitate research for articles specifically related to each duodenal cystic lesions and better understanding of these diseases, as some may have malignant potential. resumen Paciente femenina, de 60 años de edad, tenía quejas dispépticas. La endoscopía digestiva reveló lesión subepitelial ubicada en la segunda porción del duodeno con aspecto quístico (signo de la tienda de campaña), de 8 mm en su mayor diámetro. Se realizó biopsia de la lesión. El análisis histopatológico mostró dilatación de los ductos lobulares de las glándulas de Brunner, acompañada por elementos estromales dispersos, identificando un quiste de las glándulas duodenales. Es un diagnóstico diferencial de sangrado intestinal, dispepsia, enfermedad por reflujo gastroesofágico (ERGE), malabsorción y anemia. La nomenclatura es importante tanto para buscar artículos específicos de cada lesión quística en el duodeno como para mejor caracterizar esas lesiones, puesto que algunas pueden tener potencial maligno. resumo Paciente do sexo feminino, 60 anos, com queixas dispépticas. A endoscopia digestiva revelou lesão subepitelial localizada na segunda porção do duodeno com aspecto cístico (sinal da tenda positivo), de 8 mm no seu maior diâmetro. Biópsia da lesão foi realizada. A análise histopatológica mostrou dilatação dos ductos lobulares das glândulas de Brunner, acompanhada por elementos estromais dispersos, caracterizando um cisto da glândula de Brunner. É um diagnóstico diferencial de sangramento intestinal, dispepsia, doença do refluxo gastroesofágico (DRGE), má absorção e anemia. A nomenclatura é importante tanto para a pesquisa de artigos específicos de cada lesão cística no duodeno quanto para melhor caracterização dessas lesões, uma vez que algumas podem apresentar potencial maligno.

Journal Article; Case report Duodenal duplication cysts are rare congenital abnormalities which are more commonly diagnosed in infancy and childhood. However, in rare cases, these lesions can remain asymptomatic until adulthood. The combination of duplication cyst and pancreas divisum is extremely rare and both conditions have been linked with acute recurrent pancreatitis. We present the case of a 37 years-old patient who presented with repeated episodes of acute pancreatitis. By means of magnetic resonance imaging and endoscopic ultrasonography we discovered a duplication cyst whose cavity received drainage from the dorsal pancreas. After opening the cyst cavity to the duodenal lumen with a needle knife the patient presented no further episodes in the clinical follow-up. Comparable literature findings and therapeutic options for these abnormalities are discussed with regard to the presented case. Yes