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Objective: Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disorder of the gastrointestinal tract which has an unknown etiology. In this study, we aimed to investigate the fatty liver disease frequency in IBD patients using transient elastography (TE) which is a non-invasive and accurate method for the diagnosis of liver fibrosis. Material and Methods: The data were collected from registered patients retrospectively. On the basis of previous studies, a cut-off value of 238 dB/m for controlled attenuation parameter (CAP) was used for the diagnosis of hepatic steatosis. In this study we have also settled CAP value above 238 dB/m as fatty liver. Results: A total of 99 patients were enrolled in the study. Mean age was 45.59 ± 11.72 years and 41 (41.4%) patients were female. Fifty-eight patients (58.6%) had Crohn’s disease, 39 (39.4%) had ulcerative colitis and 2 (2.0%) had indeterminate colitis. In 8 (8.1%) patients extra-large probe and in 91 (91.9%) patients medium probe was used to detect liver steatosis. Fatty liver disease was detected in 44 (44.4%) patients with IBD. Conclusion: Despite the nutrition disorders in IBD, fatty liver disease was seen in 44.4% of patients in our cohort. However, fatty liver disease may be seen without any aminotransferase elevation in IBD patients. Therefore, liver steatosis should always be kept in mind and careful attention should be paid during follow-up of patients with IBD in our daily practice.

Background: The aspartate aminotransferases (AST) to platelet ratio index (APRI) may serve as a noninvasive marker to assess liver fibrosis. Objectives: To assess the diagnostic ability of the APRI for prediction of fibrosis in patients with chronic hepatitis B (CHB), chronic hepatitis C (CHC), and non-alcoholic fatty liver disease (NAFLD). Patients and Methods: This retrospective study included 207 patients with CHB,108 with CHC, and 140 patients with NAFLD. The APRI was calculated as (AST level/upper normal limit for AST)/platelet counts (109/L) x 100. The stage of liver fibrosis in patients with chronic viral hepatitis was graded using the METAVIR scale. The Kleiner system for grading fibrosis was used in patients with NAFLD. Results: Bivariate correlation analyses showed that the APRI was significantly associated with fibrosis scores in patients with CHC (p = 0.2634, p = 0.0059) and NAFLD (p = 0.2273, p = 0.0069), but not in those with CHB (p = 0.1005, p = 0.1495). Receiver operating characteristic (ROC) curves were used for assessing the ability of the APRI as a predictor of the absence or presence of liver fibrosis (fibrosis score of 0 vs fibrosis scores of 1-4). In patients with CHC, the APRI showed a sensitivity of 72.7% and a specificity of 62.4% for detection of fibrosis (p