1. A short questionnaire for the assessment of quality of life in patients with chronic obstructive pulmonary disease: psychometric properties of VQ11
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Grégory Ninot, Christian Préfaut, Franck Soyez, Dynamique des capacités humaines et des conduites de santé (EPSYLON), Université de Montpellier (UM)-Université Paul-Valéry - Montpellier 3 (UPVM)-Université Montpellier 1 (UM1), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), This work was supported by Montpellier University Hospital (CHRU), GlaxoSmithKline France, Novartis, Société de Pneumologie de Langue Française, Association Nationale pour les Traitements à Domicile les Innovations et la Recherche, Fontalvie Group., Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), BMC, Ed., and Université Montpellier 1 (UM1)-Université Paul-Valéry - Montpellier 3 (UPVM)-Université de Montpellier (UM)
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BODE index ,Adult ,Male ,medicine.medical_specialty ,Psychometrics ,Health-related quality of life ,Concurrent validity ,Validity ,Hospital Anxiety and Depression Scale ,03 medical and health sciences ,Pulmonary Disease, Chronic Obstructive ,0302 clinical medicine ,Quality of life ,Surveys and Questionnaires ,medicine ,Humans ,030212 general & internal medicine ,ComputingMilieux_MISCELLANEOUS ,VQ11 ,Aged ,Aged, 80 and over ,COPD ,business.industry ,Research ,Chronic obstructive pulmonary disease ,Public Health, Environmental and Occupational Health ,Reproducibility of Results ,General Medicine ,Middle Aged ,medicine.disease ,Confirmatory factor analysis ,3. Good health ,Respiratory Function Tests ,030228 respiratory system ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,Brief questionnaire ,Physical therapy ,Quality of Life ,Female ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,France ,business - Abstract
Background There is a need for a validated short instrument that can be used in routine practice to quantify potential short-term change in Health-Related Quality of Life (HRQoL) in patients with chronic obstructive pulmonary disease (COPD). Our aim is to determine the validity and reliability of the VQ11 questionnaire dedicated to the routine assessment of HRQoL. Methods 181 COPD patients (40–85 yrs, I to IV GOLD stages) completed the VQ11, and several tests. One week later, 49 of these patients completed the VQ11 again. Results Confirmatory factor analysis supported the two-level hierarchical structure of the VQ11 with 11 items covering three components and HRQoL at a higher level. The VQ11 showed good internal consistency and good reproducibility (r = 0.88). Concurrent validity showed significant correlations between VQ11 total scores and St George’s Respiratory Questionnaire-C (r = 0.70), Short Form-36 (r = -0.66 for the physical component and -0.63 for the mental component). We obtained significant correlations with MRC Dyspnea Grades (r = 0.59), the Hospital Anxiety and Depression Scale total score (r = 0.62), and the BODE index (r = 0.53). Conclusion The VQ11 has good measurement properties and provides a valid and reliable measure of COPD-specific HRQoL. It is ready for use in routine practice. Clinical registration The study was approved by the University of Montpellier 1 Ethics Committee and the Regional Ethics Committee (authorization number: A00332-53).
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