351 results on '"G. Pellegrino"'
Search Results
2. Minimally Invasive Treatment in Benign Prostatic Hyperplasia (BPH)
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L. V. Sciacqua MD, A. Vanzulli MD, R. Di Meo MD, G. Pellegrino MD, R. Lavorato BSc/MSc, G. Vitale MD, and G. Carrafiello MD
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Review efficacy and safety of minimally-invasive treatments for Low Urinary Tract Symptoms (LUTS) in patients affected by Benign Prostate Hyperplasia (BPH). We performed a systematic review of the literature from 1993 to 2022 leveraging original research articles, reviews, and case-studies published in peer-reviewed journals and stored in public repositories. Prostate artery embolization (PAE), transurethral needle ablation (TUNA), transurethral microwave thermotherapy (TUMT), high intensity focused ultrasound (HIFU), laser treatments and Cryoablation are valid and safe alternatives to the gold standard (surgery) in the treatment of LUTS in patients affected by BPH, with fewer undesired effects being reported.
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- 2023
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3. Effect of light on ultrastructure of chloroplasts and post-storage performance of Hydrangea macrophylla (Hydrangeaceae)
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G. PELLEGRINO, I. PERROTTA, and A.M. PALERMO
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electron microscopy ,leaf morphology ,hortensia ,organelle ,stress recovery. ,Botany ,QK1-989 - Abstract
The plants of Hydrangea are normally stored in dark conditions during shipping. In this study, Hydrangea macrophylla plants were stored for 0-15 d in light or darkness to evaluate the effect of the storage duration and condition on the chloroplast ultrastructure and chlorophyll (Chl) content. Moreover, the plants stored in the dark were transferred to a growth chamber to evaluate their resilience. The plants stored in the dark showed a decrease in number of chloroplasts and starch grains, and granal and intergranal thylakoids with irregular morphology. On the contrary, the same leaves showed an increase of the number of plastoglubuli. The Chl content of the plants remained relatively unchanged during storage under light conditions, but decreased under dark conditions. Transplanted plants stored for 3-9 d in the dark showed normal oval-shape chloroplasts and orderly and dense thylakoids. On the contrary, the plants stored for 12 or 15 d in the dark did not recover normal leaf phenotypes or chloroplast ultrastructure. This study demonstrated that long duration of darkness altered irreversibly the chloroplast ultrastructure and the photosynthetic ability and affected the regrowth potential of Hydrangea macrophylla plants.
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- 2019
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4. High-latitude Southern Hemisphere fire history during the mid- to late Holocene (6000–750 BP)
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D. Battistel, N. M. Kehrwald, P. Zennaro, G. Pellegrino, E. Barbaro, R. Zangrando, X. X. Pedeli, C. Varin, A. Spolaor, P. T. Vallelonga, A. Gambaro, and C. Barbante
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Environmental pollution ,TD172-193.5 ,Environmental protection ,TD169-171.8 ,Environmental sciences ,GE1-350 - Abstract
We determined the specific biomass burning biomarker levoglucosan in an ice core from the TALos Dome Ice CorE drilling project (TALDICE) during the mid- to late Holocene (6000–750 BP). The levoglucosan record is characterized by a long-term increase with higher rates starting at ∼ 4000 BP and peaks between 2500 and 1500 BP. The anomalous increase in levoglucosan centered at ∼ 2000 BP is consistent with other Antarctic biomass burning records. Multiple atmospheric phenomena affect the coastal Antarctic Talos Dome drilling site, where the Southern Annular Mode (SAM) is the most prominent as the Southern Annular Mode Index (SAMA) correlates with stable isotopes in precipitation throughout the most recent 1000 years of the ice core. If this connection remains throughout the mid- to late Holocene, then our results demonstrate that changes in biomass burning, rather than changes in atmospheric transport, are the major influence on the TALDICE levoglucosan record. Comparisons with charcoal syntheses help evaluate fire sources, showing a greater contribution from southern South American fires than from Australian biomass burning. The levoglucosan peak centered at ∼ 2000 BP occurs during a cool period throughout the Southern Hemisphere, yet during a time of increased fire activity in both northern and southern Patagonia. This peak in biomass burning is influenced by increased vegetation in southern South America from a preceding humid period, in which the vegetation desiccated during the following cool, dry period. The Talos Dome ice core record from 6000 to ∼ 750 BP currently does not provide clear evidence that the fire record may be strongly affected by anthropogenic activities during the mid- to late Holocene, although we cannot exclude at least a partial influence.
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- 2018
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5. Comparison of the spatial resolution of source imaging techniques in high-density EEG and MEG
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T. Hedrich, G. Pellegrino, E. Kobayashi, J.M. Lina, and C. Grova
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EEG ,MEG ,Source imaging ,Resolution matrix ,Spatial resolution ,Somatosensory ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Background: The present study aims at evaluating and comparing electrical and magnetic distributed source imaging methods applied to high-density Electroencephalography (hdEEG) and Magnetoencephalography (MEG) data. We used resolution matrices to characterize spatial resolution properties of Minimum Norm Estimate (MNE), dynamic Statistical Parametric Mapping (dSPM), standardized Low-Resolution Electromagnetic Tomography (sLORETA) and coherent Maximum Entropy on the Mean (cMEM, an entropy-based technique). The resolution matrix provides information of the Point Spread Functions (PSF) and of the Crosstalk functions (CT), this latter being also called source leakage, as it reflects the influence of a source on its neighbors. Methods: The spatial resolution of the inverse operators was first evaluated theoretically and then with real data acquired using electrical median nerve stimulation on five healthy participants. We evaluated the Dipole Localization Error (DLE) and the Spatial Dispersion (SD) of each PSF and CT map. Results: cMEM showed the smallest spatial spread (SD) for both PSF and CT maps, whereas localization errors (DLE) were similar for all methods. Whereas cMEM SD values were lower in MEG compared to hdEEG, the other methods slightly favored hdEEG over MEG. In real data, cMEM provided similar localization error and significantly less spatial spread than other methods for both MEG and hdEEG. Whereas both MEG and hdEEG provided very accurate localizations, all the source imaging methods actually performed better in MEG compared to hdEEG according to all evaluation metrics, probably due to the higher signal-to-noise ratio of the data in MEG. Conclusion: Our overall results show that all investigated methods provide similar localization errors, suggesting very accurate localization for both MEG and hdEEG when similar number of sensors are considered for both modalities. Intrinsic properties of source imaging methods as well as their behavior for well-controlled tasks, suggest an overall better performance of cMEM in regards to spatial resolution and spatial leakage for both hdEEG and MEG. This indicates that cMEM would be a good candidate for studying source localization of focal and extended generators as well as functional connectivity studies.
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- 2017
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6. LEGIONELLOSI: MICROBIOLOGIA, LINEE GUIDA E SORVEGLIANZA NELLA REGIONE MOLISE
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D. Sferra, G. Pellegrino, L. Di Pardo, A. Melloni, E. Barone, M. Piccirilli, M. Giancola, G. Caruso, and A. Manuppella
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Microbiology ,QR1-502 - Published
- 2007
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7. Optimized Artificial Intelligence for Enhanced Ectasia Detection Using Scheimpflug-Based Corneal Tomography and Biomechanical Data
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Ambrósio, Renato, Jr, Machado, Aydano P., Leão, Edileuza, Lyra, João Marcelo G., Salomão, Marcella Q., Esporcatte, Louise G. Pellegrino, da Fonseca Filho, João B.R., Ferreira-Meneses, Erica, Sena, Nelson B., Jr, Haddad, Jorge S., Costa Neto, Alexandre, de Almeida, Gildasio Castelo, Jr, Roberts, Cynthia J., Elsheikh, Ahmed, Vinciguerra, Riccardo, Vinciguerra, Paolo, Bühren, Jens, Kohnen, Thomas, Kezirian, Guy M., Hafezi, Farhad, Hafezi, Nikki L., Torres-Netto, Emilio A., Lu, Nanji, Kang, David Sung Yong, Kermani, Omid, Koh, Shizuka, Padmanabhan, Prema, Taneri, Suphi, Trattler, William, Gualdi, Luca, Salgado-Borges, José, Faria-Correia, Fernando, Flockerzi, Elias, Seitz, Berthold, Jhanji, Vishal, Chan, Tommy C.Y., Baptista, Pedro Manuel, Reinstein, Dan Z., Archer, Timothy J., Rocha, Karolinne M., Waring, George O., IV, Krueger, Ronald R., Dupps, William J., Khoramnia, Ramin, Hashemi, Hassan, Asgari, Soheila, Momeni-Moghaddam, Hamed, Zarei-Ghanavati, Siamak, Shetty, Rohit, Khamar, Pooja, Belin, Michael W., and Lopes, Bernardo T.
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- 2023
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8. Deconvolution of hemodynamic responses along the cortical surface using personalized functional near infrared spectroscopy
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A Machado, Z Cai, T Vincent, G Pellegrino, J-M Lina, E Kobayashi, and C Grova
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Medicine ,Science - Abstract
Abstract In functional near infrared spectroscopy (fNIRS), deconvolution analysis of oxy and deoxy-hemoglobin concentration changes allows estimating specific hemodynamic response functions (HRF) elicited by neuronal activity, taking advantage of the fNIRS excellent temporal resolution. Diffuse optical tomography (DOT) is also becoming the new standard reconstruction procedure as it is more accurate than the modified Beer Lambert law approach at the sensor level. The objective of this study was to assess the relevance of HRF deconvolution after DOT constrained along the cortical surface. We used local personalized fNIRS montages which consists in optimizing the position of fNIRS optodes to ensure maximal sensitivity to subject specific target brain regions. We carefully evaluated the accuracy of deconvolution when applied after DOT, using realistic simulations involving several HRF models at different signal to noise ratio (SNR) levels and on real data related to motor and visual tasks in healthy subjects and from spontaneous pathological activity in one patient with epilepsy. We demonstrated that DOT followed by deconvolution was able to accurately recover a large variability of HRFs over a large range of SNRs. We found good performances of deconvolution analysis for SNR levels usually encountered in our applications and we were able to reconstruct accurately the temporal dynamics of HRFs in real conditions.
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- 2021
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9. Turtles on the trash track: loggerhead turtles exposed to floating plastic in the Mediterranean Sea
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A Arcangeli, F Maffucci, F Atzori, M Azzolin, I Campana, L Carosso, R Crosti, F Frau, L David, N Di-Méglio, M Roul, M Gregorietti, V Mazzucato, G Pellegrino, A Giacoletti, M Paraboschi, A Zampollo, GA de Lucia, and S Hochscheid
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Zoology ,QL1-991 ,Botany ,QK1-989 - Abstract
Loggerhead turtles Caretta caretta spend most of their life in large marine areas occupying a variety of habitats where they are exposed to different types of threats. Among these, marine litter poses a risk of entanglement or ingestion. Areas of risk exposure can be identified where the species overlap with litter accumulations, but gathering data on this highly mobile species and marine litter, especially in high sea areas, is challenging. Here we analysed 5 years of sea turtle and marine litter data collected by a network of research bodies along fixed trans-border transects in the Mediterranean Sea. Ferries were used as observation platforms to gather systematic data on a seasonal basis using standard protocols. Loggerhead turtle sightings over time and space were compared in terms of sightings per unit effort, and risk-exposure areas were assessed based on seasonal overlap of species hot spots and high-density plastic areas revealed by kernel analysis. In almost 180000 km surveyed, 1258 sea turtles were recorded, concentrated mostly in the central Adriatic Sea and Sardinia-Sicilian channels during all seasons, and in the central Tyrrhenian Sea during spring. Plastic comprised the highest fraction of litter items detected. Several areas of higher risk exposure, both permanent and seasonal, were identified, mainly in the Adriatic Sea and during the spring-summer seasons. Records of both species and floating litter were highly variable, underlying the need for continuous long-term monitoring to develop sound conservation and management measures, especially in the identified areas of risk exposure.
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- 2019
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10. Pain perception in paediatric patients: evaluation of computerised anaesthesia delivery system vs conventional infiltration anaesthesia in paediatric patients
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F S, Ludovichetti, A, Zuccon, G, Zambon, G, Pellegrino, A G, Signoriello, E, Milia, A, Bortone, A, Gracco, and S, Mazzoleni
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Adolescent ,Computerised anaesthesia delivery sistem ,Infiltration anaesthesia ,Pain perception ,Anesthesia, Dental ,Child, Preschool ,Humans ,Pain ,Anesthetics, Local ,Child ,Anesthesia, Local - Abstract
The aim of the present study is to compare the effectiveness of a computerised system (QuickSleeper) compared to traditional syringe in injection of local anaesthetic focusing on the perception of anxiety and pain in paediatric patients.Study design: 100 children aged between 3 and 15 years in need of two dental treatments that required local anaesthesia were selected and treated randomly but alternately with computerised and traditional local anaesthesia. After each anaesthetic injection, patient's anxiety was measured using the Venham test.Electronic anaesthesia showed statistically significant better results than traditional anaesthesia according to the Venham pain scale, in both mandibular and maxillary sites. Statistics: Data were analysed using the paired Wilcoxon test.The computer-assisted anaesthesia system resulted in a significantly lower pain perception score and yielded to helpful, cooperative behaviour. For this reason, it is an advantageous alternative to traditional injection anaesthesia and can avoid invasive treatments and trauma for young patients.
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- 2022
11. Turtles on the trash track: loggerhead turtles exposed to floating plastic in the Mediterranean Sea
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G. A. de Lucia, G. Pellegrino, Antonella Arcangeli, Martina Gregorietti, Léa David, Francesca Frau, Antonio Giacoletti, M. Azzolin, Sandra Hochscheid, Veronica Mazzucato, Ilaria Campana, Fulvio Maffucci, Marine Roul, Miriam Paraboschi, Nathalie Di-Méglio, R. Crosti, Fabrizio Atzori, Arianna Zampollo, Lara Carosso, ARCANGELI A, MAFFUCCI F, ATZORI F, AZZOLIN M, CAMPANA I, CAROSSO L, CROSTI R, FRAU F., DAVID L, DI-MÉGLIO N, ROUL M, GREGORIETTI M, MAZZUCATO V., PELLEGRINO G, GIACOLETTI A, PARABOSCHI M, ZAMPOLLO A, DE LUCIA G A, and HOCHSCHEID S
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Fishery ,Geography ,Mediterranean sea ,Ecology ,QL1-991 ,Track (disk drive) ,QK1-989 ,Marine debris ,Botany ,Loggerhead turtle, marine litter, Mediterranean Sea, monitoring, risk assessment ,Zoology ,Nature and Landscape Conservation - Abstract
Loggerhead turtles (Caretta caretta) spend most of their life in large marine areas occupying a variety of habitats where they are exposed to different types of threats. Among these, marine litter is known to pose a risk of entanglement or ingestion. Areas of risk exposure can be identified where the species overlap with litter accumulations, but gathering data on this highly mobile species and marine litter, especially in high sea areas, is challenging. Here we analysed five years of sea turtle and marine litter data collected by a network of research bodies along fixed trans-border transects in the Mediterranean Sea. Ferries were used as observation platforms to gather systematic data on a seasonal basis using standard protocols. The Sightings Per Unit of Effort was used as an index to compare loggerhead turtle sightings over time and space, and risk exposure areas were assessed based on seasonal overlap of species hot spots and high-density plastic areas revealed by Kernel analysis. In almost 180,000 km surveyed, 1258 sea turtles were recorded, concentrated mostly during all seasons in the central Adriatic Sea and Sardinia-Sicilian channels, and during spring in central Tyrrhenian. Plastic was the highest fraction of litter items detected. Several areas of higher risk exposure, both permanent and seasonal, were identified, mainly in the Adriatic Sea and during the spring-summer seasons. Records of both species and floating litter were highly variable, underlying the need for continuous long-term monitoring to develop sound conservation and management measures, especially in the identified areas of risk exposure.
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- 2019
12. Cetacean presence and distribution in the central Mediterranean Sea and potential risks deriving from plastic pollution
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Francesca Frau, Gianluca Sarà, Antonella Arcangeli, Martina Gregorietti, G. Pellegrino, Fabrizio Atzori, Lara Carosso, Gregorietti M., Atzori F., Carosso L., Frau F., Pellegrino G., Sara' G., and Arcangeli A.
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Settore BIO/07 - Ecologia ,Cetacean distribution ,Species Distribution Models ,Biodiversity ,Pelagic zone ,Aquatic Science ,Oceanography ,Pollution ,Plastic marine litter ,Fishery ,Mediterranean sea ,Geography ,Marine mammal ,Habitat ,Sardinian-Sicilian Channels ,Abundance (ecology) ,Mediterranean Sea ,Animals ,Cetacea ,Transect ,Plastic pollution ,Plastics ,Ecosystem ,Risk assessment - Abstract
The Sardinian and Sicilian Channels are considered hotspots of biodiversity and key ecological passages between Mediterranean sub-basins, but with significant knowledge gaps about marine mammal presence and potential threats they face. Using data collected between 2013 and 2019 along fixed transects, inter and intra-annual cetacean index of abundance was assessed. Habitat suitability, seasonal hot spots, and risk exposure for plastic were performed using the Kernel analysis and the Biomod2 R-package. 661 sightings of 8 cetacean species were recorded, with bottlenose and striped dolphins as the most sighted species. The north-eastern pelagic sector, the coastal waters and areas near ridges resulted the most suitable habitats for these species. The risk analysis identified the Tunis, Palermo, and Castellammare gulfs and the Egadi Island as areas of particular risk of plastic exposure. The study represents a great improvement for cetacean knowledge in this region and contributes to the development of effective conservation strategies.
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- 2021
13. Trends in summer presence of fin whales in the Western Mediterranean Sea Region: new insights from a long-term monitoring program
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Paola Tepsich, M. Azzolin, G. Pellegrino, Aurelie Moulins, Marine Roul, Nathalie Di-Méglio, Sebastien Saintignan, Léa David, Veronica Mazzucato, Fabrizio Atzori, Ilaria Campana, Massimiliano Rosso, Francesca Frau, Antonella Arcangeli, Martina Gregorietti, Lara Carosso, Simone Cominelli, Roberto Crosti, Miriam Paraboschi, Ilaria Schettino, and Clara Monaco
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0106 biological sciences ,Fin whale ,010504 meteorology & atmospheric sciences ,Conservation Biology ,Population ,Marine Biology ,Distribution ,Assessment ,01 natural sciences ,Mediterranean Basin ,General Biochemistry, Genetics and Molecular Biology ,Mediterranean sea ,biology.animal ,IUCN Red List ,education ,Transect ,0105 earth and related environmental sciences ,education.field_of_study ,Balaenoptera ,biology ,Ecology ,Whale ,010604 marine biology & hydrobiology ,General Neuroscience ,General Medicine ,biology.organism_classification ,Geography ,Biogeography ,Conservation status ,Physical geography ,Trends ,General Agricultural and Biological Sciences ,Zoology - Abstract
Background The Mediterranean subpopulation of fin whale Balaenoptera physalus (Linnaeus, 1758) has recently been listed as Vulnerable by the IUCN Red List of threatened species. The species is also listed as species in need of strict protection under the Habitat Directive and is one of the indicators for the assessment of Good Environmental Status under the MSFD. Reference values on population abundance and trends are needed in order to set the threshold values and to assess the conservation status of the population. Methods Yearly summer monitoring using ferries as platform of opportunity was performed since 2008 within the framework of the FLT Med Network. Data were collected along several fixed transects crossing the Western Mediterranean basin and the Adriatic and Ionian region. Species presence, expressed by density recorded along the sampled transects, was inspected for assessing interannual variability together with group size. Generalized Additive Models were used to describe density trends over a 11 years’ period (2008–2018). A spatial multi-scale approach was used to highlight intra-basin differences in species presence and distribution during the years. Results Summer presence of fin whales in the western Mediterranean area showed a strong interannual variability, characterized by the alternance of rich and poor years. Small and large groups of fin whales were sighted only during rich years, confirming the favorable feeding condition influencing species presence. Trends highlighted by the GAM can be summarized as positive from 2008 to 2013, and slightly negative from 2014 to 2018. The sub-areas analysis showed a similar pattern, but with a more stable trend during the second period in the Pelagos Sanctuary sub-area, and a negative one in the other two sub-areas. Our findings further confirm the need for an integrated approach foreseeing both, large scale surveys and yearly monitoring at different spatial scales to correct and interpret the basin wide abundance estimates, and to correlate spatial and temporal trends with the ecological and anthropogenic drivers.
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- 2020
14. Systemic sclerosis Progression INvestiGation (SPRING) Italian registry: demographic and clinico-serological features of scleroderma spectrum
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C. Ferri, D. Giuggioli, S. Guiducci, F. Lumetti, G. Bajocchi, L. Magnani, V. Codullo, A. Ariani, F. Girelli, V. Riccieri, G. Pellegrino, S. Bosello, R. Foti, E. Visalli, G. Amato, A. Benenati, Giovanna Cuomo, F. Iannone, F. Cacciapaglia, R. De Angelis, F. Ingegnoli, R. Talotta, C. Campochiaro, L. Dagna, G. De Luca, S. Bellando-Randone, A. Spinella, G. Murdaca, N. Romeo, M. De Santis, E. Generali, S. Barsotti, A. Della Rossa, I. Cavazzana20, F. Dall’Ara20, M. G. Lazzaroni20, F. Cozzi22, A. Doria22, E. Pigatto22, E. Zanatta22, G. Ciano23, L. Beretta24, G. Abignano25, S. D’Angelo25, G. Mennillo25, G. Bagnato26, F. Calabrese27, M. Caminiti27, G. Pagano Mariano27, E. Battaglia28, E. Lubrano29, G. Zanframundo4, A. Iuliano30, F. Furini31, A. Zanetti32, G. Carrara32, F. Rumi32, C. A. Scirè31, M. Matucci-Cerinic2, on behalf of the Italian Society of Rheumatology (SIR), Ferri, C., Giuggioli, D., Guiducci, S., Lumetti, F., Bajocchi, G., Magnani, L., Codullo, V., Ariani, A., Girelli, F., Riccieri, V., Pellegrino, G., Bosello, S., Foti, R., Visalli, E., Amato, G., Benenati, A., Cuomo, Giovanna, Iannone, F., Cacciapaglia, F., De Angelis, R., Ingegnoli, F., Talotta, R., Campochiaro, C., Dagna, L., De Luca, G., Bellando-Randone, S., Spinella, A., Murdaca, G., Romeo, N., De Santis, M., Generali, E., Barsotti, S., Della Rossa, A., Cavazzana20, I., Dall’Ara20, F., Lazzaroni20, M. G., Cozzi22, F., Doria22, A., Pigatto22, E., Zanatta22, E., Ciano23, G., Beretta24, L., Abignano25, G., D’Angelo25, S., Mennillo25, G., Bagnato26, G., Calabrese27, F., Caminiti27, M., Pagano Mariano27, G., Battaglia28, E., Lubrano29, E., Zanframundo4, G., Iuliano30, A., Furini31, F., Zanetti32, A., Carrara32, G., Rumi32, F., Scirè31, C. A., Matucci-Cerinic2, M., and behalf of the Italian Society of Rheumatology (SIR), On
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systemic sclerosis, VEDOSS, Raynaud’s phenomenon - Abstract
Objective. Systemic sclerosis (SSc) is a severe multiple-organ disease charac- terised by unpredictable clinical course, inadequate response to treatment, and poor prognosis. National SSc registries may provide large and representative patients cohorts required for descriptive and prognostic studies. Therefore, the Italian Society of Rheumatology pro- moted the registry SPRING (Systemic sclerosis Progression INvestiGation). Methods. The SPRING is a multi- centre rheumatological cohort study encompassing the wide scleroder- ma spectrum, namely the primary Raynaud’s phenomenon (pRP), sus- pected secondary RP, Very Early Diag- nosis of Systemic Sclerosis (VEDOSS), and definite SSc. Here we describe the demographic and clinical characteris- tics of 2,028 Italian patients’ popula- tion at the initial phase of enrollment, mainly focusing on the cohort of 1,538 patients with definite SSc. Results. Definite SSc showed signifi- cantly higher prevalence of digital ul- cers, capillaroscopic ‘late’ pattern, oesophageal and cardio-pulmonary involvement compared to VEDOSS, as expected on the basis of the followed classification criteria. The in-depth analysis of definite SSc revealed that male gender, diffuse cu- taneous subset, and anti-Scl70 sero- positivity were significantly associated with increased prevalence of the most harmful disease manifestations. Similarly, patients with very short RP duration (≤1 year) at SSc diagnosis showed a statistically increased preva- lence of unfavorable clinico-serologi- cal features. Conclusion. Nationwide registries with suitable patients’ subsetting and follow-up studies since the prodromal phase of the disease may give us valu- able insights on the SSc natural history and main prognostic factors.
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- 2020
15. Optimized Artificial Intelligence for Enhanced Ectasia Detection Using Scheimpflug-Based Corneal Tomography and Biomechanical Data.
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AMBRÓSIO JR, RENATO, MACHADO, AYDANO P., LEÃO, EDILEUZA, LYRA, JOÃO MARCELO G., SALOMÃO, MARCELLA Q., ESPORCATTE, LOUISE G. PELLEGRINO, FILHO, JOÃO B. R. DA FONSECA, FERREIRA-MENESES, ERICA, SENA JR, NELSON B., HADDAD, JORGE S., NETO, ALEXANDRE COSTA, DE ALMEIDA JR, GILDASIO CASTELO, ROBERTS, CYNTHIA J., ELSHEIKH, AHMED, VINCIGUERRA, RICCARDO, VINCIGUERRA, PAOLO, BÜHREN, JENS, KOHNEN, THOMAS, KEZIRIAN, GUY M., and HAFEZI, FARHAD
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- 2022
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16. Paleomagnetic Evidence for 25–15 Ma Crust Fragmentation of North Indochina (23–26°N): Consequence of Collision With Greater India NE Corner?
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Catalina Hernandez-Moreno, Siyu Chen, Fabio Speranza, Alessandra G. Pellegrino, Rosanna Maniscalco, and Bo Zhang
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Paleomagnetism ,Paleomagnetism of Triassic‐Cretaceous red beds from the Simao ,Ailao Shan-Red River shear zone ,Fragmentation (computing) ,paleomagnetism ,and Lanping "blocks" ,Crust ,block rotation ,Indochina ,Collision ,Paleomagnetism of Triassic‐Cretaceous red beds from the Simao, Chuandian, and Lanping "blocks" ,Paleontology ,Geophysics ,paleomagnetism, block rotation, intracontinental deformation, Indochina, Ailao Shan-Red River shear zone ,"Blocks" are in fact brocken in 2‐6 km wide sub‐blocks rotating independently both CW and CCW ,intracontinental deformation ,Geochemistry and Petrology ,Chuandian ,Crust fragmentation of north Indochina related to collision with Greater India NE corner at ~30 Ma ,Geology - Published
- 2019
17. An integrated approach for cetacean knowledge and conservation in the central Mediterranean Sea using research and social media data sources
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Miriam Paraboschi, G. Pellegrino, Giancarlo Giacomini, Jessica Alessi, Ilaria Campana, Margherita Silvestri, Gianni Pavan, Giandomenico Ardizzone, Dario Angeletti, Daniela Silvia Pace, Valentina Cafaro, and Antonella Arcangeli
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Ecology ,business.industry ,cetacean ,conservation ,distribution ,Maxent ,Mediterranean Sea ,social media ,Distribution (economics) ,Aquatic Science ,Integrated approach ,Oceanography ,Mediterranean sea ,Geography ,Social media ,business ,Nature and Landscape Conservation - Published
- 2019
18. Characterisation of the Hamamatsu photomultipliers for the KM3NeT Neutrino Telescope
- Author
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Aiello, S. Akrame, S.E. Ameli, F. Anassontzis, E.G. Andre, M. Androulakis, G. Anghinolfi, M. Anton, G. Ardid, M. Aublin, J. Avgitas, T. Baars, M. Bagatelas, C. Barbarino, G. Baret, B. Barrios-Martí, J. Belias, A. Berbee, E. Berg, A.V.D. Bertin, V. Biagi, S. Biagioni, A. Biernoth, C. Bormuth, R. Boumaaza, J. Bourret, S. Bouwhuis, M. Bozza, C. Branzaş, H. Briukhanova, N. Bruijn, R. Brunner, J. Buis, E. Buompane, R. Busto, J. Calvo, D. Capone, A. Caramete, L. Celli, S. Chabab, M. Cherubini, S. Chiarella, V. Chiarusi, T. Circella, M. Cocimano, R. Coelho, J.A.B. Coleiro, A. Molla, M.C. Coniglione, R. Coyle, P. Creusot, A. Cuttone, G. D'Onofrio, A. Dallier, R. Sio, C.D. Palma, I.D. Díaz, A.F. Distefano, C. Domi, A. Donà, R. Donzaud, C. Dornic, D. Dörr, M. Durocher, M. Eberl, T. Eijk, D.V. Bojaddaini, I.E. Elsaesser, D. Enzenhöfer, A. Ferrara, G. Fusco, L.A. Gal, T. Garufi, F. Gauchery, S. Geißelsöder, S. Gialanella, L. Giorgio, E. Giuliante, A. Gozzini, S.R. Ruiz, R.G. Graf, K. Grasso, D. Grégoire, T. Grella, G. Hallmann, S. Haren, H.V. Heid, T. Heijboer, A. Hekalo, A. Hernández-Rey, J.J. Hofestädt, J. Illuminati, G. James, C.W. Jongen, M. Jongewaard, B. De Jong, M. De Jong, P. Kadler, M. Kalaczyński, P. Kalekin, O. Katz, U.F. Chowdhury, N.R.K. Kieft, G. Kießling, D. Koffeman, E.N. Kooijman, P. Kouchner, A. Kreter, M. Kulikovskiy, V. Lahmann, R. Breton, R.L. Leone, F. Leonora, E. Levi, G. Lincetto, M. Lonardo, A. Longhitano, F. Lotze, M. Loucatos, S. Maggi, G. Mańczak, J. Mannheim, K. Margiotta, A. Marinelli, A. Markou, C. Martin, L. Martínez-Mora, J.A. Martini, A. Marzaioli, F. Mele, R. Melis, K.W. Migliozzi, P. Migneco, E. Mijakowski, P. Miranda, L.S. Mollo, C.M. Morganti, M. Moser, M. Moussa, A. Muller, R. Musumeci, M. Nauta, L. Navas, S. Nicolau, C.A. Nielsen, C. Organokov, M. Orlando, A. Panagopoulos, V. Papalashvili, G. Papaleo, R. Pǎvǎlaş, G.E. Pellegrini, G. Pellegrino, C. Pérez Romero, J. Perrin-Terrin, M. Piattelli, P. Pikounis, K. Pisanti, O. Poirè, C. Polydefki, G. Poma, G.E. Popa, V. Post, M. Pradier, T. Pühlhofer, G. Pulvirenti, S. Quinn, L. Raffaelli, F. Randazzo, N. Razzaque, S. Real, D. Resvanis, L. Reubelt, J. Riccobene, G. Richer, M. Rovelli, A. Salvadori, I. Samtleben, D.F.E. Sánchez Losa, A. Sanguineti, M. Santangelo, A. Sapienza, P. Schermer, B. Sciacca, V. Seneca, J. Sgura, I. Shanidze, R. Sharma, A. Simeone, F. Sinopoulou, A. Spisso, B. Spurio, M. Stavropoulos, D. Steijger, J. Stellacci, S.M. Strandberg, B. Stransky, D. Stüven, T. Taiuti, M. Tatone, F. Tayalati, Y. Tenllado, E. Thakore, T. Timmer, P. Trovato, A. Tsagkli, S. Tzamariudaki, E. Tzanetatos, D. Valieri, C. Vallage, B. Elewyck, V.V. Versari, F. Viola, S. Vivolo, D. Volkert, M. De Waardt, L. Wilms, J. De Wolf, E. Zaborov, D. Zornoza, J.D. Zuniga, J.
- Subjects
Physics::Instrumentation and Detectors ,Astrophysics::Instrumentation and Methods for Astrophysics - Abstract
The Hamamatsu R12199-02 3-inch photomultiplier tube is the photodetector chosen for the first phase of the KM3NeT neutrino telescope. About 7000 photomultipliers have been characterised for dark count rate, timing spread and spurious pulses. The quantum efficiency, the gain and the peak-to-valley ratio have also been measured for a sub-sample in order to determine parameter values needed as input to numerical simulations of the detector. © 2018 The Author(s).
- Published
- 2018
19. Tectonics and paleomagnetic rotation pattern of Yunnan (24°N-25°N, China): Gaoligong fault shear vs. mega-block drift
- Author
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Catalina Hernandez-Moreno, Alessandra G. Pellegrino, Congyuan Yin, Bo Zhang, Fabio Speranza, Aldo Winkler, and Rosanna Maniscalco
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Paleomagnetism ,010504 meteorology & atmospheric sciences ,010502 geochemistry & geophysics ,Strike-slip tectonics ,01 natural sciences ,Block rotation ,Yunnan (China) ,Tectonics ,Geophysics ,Gaoligong shear zone ,Shear (geology) ,Geochemistry and Petrology ,Seismology ,Geology ,0105 earth and related environmental sciences - Published
- 2018
20. Amount, composition, and spatial distribution of floating macro litter along fixed trans-border transects in the Mediterranean basin
- Author
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Ilaria Campana, Fabrizio Atzori, Roberto Crosti, Miriam Paraboschi, C. Luperini, Lara Carosso, Martina Ramazio, Gianluca Sarà, G. Pellegrino, Dario Angeletti, Antonella Arcangeli, Martina Gregorietti, Antonio Giacoletti, M. Azzolin, Valentina Di Miccoli, Arcangeli A., Campana I., Angeletti D., Atzori F., Azzolin M., Carosso L., Di Miccoli V., Giacoletti A., Gregorietti M., Luperini C., Paraboschi M., Pellegrino G., Ramazio M., Sarà Gianluca, and Crosti R.
- Subjects
0106 biological sciences ,Pollution ,Mediterranean climate ,Settore BIO/07 - Ecologia ,media_common.quotation_subject ,010501 environmental sciences ,Aquatic Science ,Structural basin ,Oceanography ,Spatial distribution ,01 natural sciences ,Mediterranean Basin ,Marine debris ,Mediterranean Sea ,Transect ,0105 earth and related environmental sciences ,media_common ,Waste Products ,Spatial Analysis ,Mediterranean Region ,Marine litter, Mediterranean, Plastic, Pollution ,010604 marine biology & hydrobiology ,Geographic Information Systems ,Environmental science ,Seasons ,Plastics ,Water Pollutants, Chemical ,Environmental Monitoring - Abstract
Marine litter is a major source of pollution in the Mediterranean basin, but despite legislative requirements, scant information is available for the ongoing assessment of this threat. Using higher size classes as proxy for litter distribution, this study gave a synoptic estimation of the amount, composition, and distribution of floating macro-litter in the Mediterranean. The average amount of macro-litter was in a range of 2-5 items/km2, with the highest in the Adriatic basin. Seasonal patterns were present in almost all study areas and were significant in the Ligurian Sea, Sardinian-Balearic basin, and Central Tyrrhenian Sea. Plastic accounted for > 80% of litter in all areas and seasons, with the highest proportion in the Adriatic Sea, Ligurian Sea, and Sicilian-Sardinian Channels; in the Bonifacio Strait, Tyrrhenian Sea, and Sardinian-Balearic basin, litter composition was instead more diverse. Spatial analysis suggested an almost homogeneous distribution of litter without evident regular aggregation zones.
- Published
- 2018
21. New hybrid polymer-ZnO nanostructures THROUGH ALD synthesis
- Author
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G. Pellegrino, S. C. Carroccio, F. Ruffino, G. G. Condorelli, V. Privitera, and G. Impellizzeri
- Subjects
polymer nanocomposites ,ALD ,polyetherimide ,ZnO ,photo-oxidation - Abstract
The development of the nanotechnologies has brought concrete benefits on our daily life, finding application in several fields. In particular, a recent strategy in the water treatment consists in the development of photocatalytic hybrid nanocomposites (HyNC), in which the inorganic photoactive material is immobilized into a polymeric matrix to prevent their dispersion in the aqueous medium . The synthesis of HyNC, in which an inorganic layer grows on a polymeric surface via covalent bonds, persists to be a challenging goal for many applications such as catalysis, sensing, and optoelectronics. Herein, we report the growth of ZnO nanostructures by Atomic Layer Deposition (ALD) technique on modified polyetherimide (PEI-ULTEM® 1000) substrates. The high quality of the ALD materials originate from the peculiar growth mechanism based on selective and self-limiting reactions between the ALD gaseous precursors and the reactive groups exposed at surface of the substrate. The growth of the material on the substrate is controlled at the atomic scale, uniformly and conformably on large areas. A photo-oxidative process of the polymer surface has been properly performed to promote the production of reactive surface-sites suitable for ALD mechanism. The chemical anchoring of the metal species from the gas-phase is demonstrated by spectroscopy, MALDI-TOF mass spectrometry as well as AFM. In the operative ALD conditions used, the chemical grafting exclusively occurred on the pre-oxidized films, whilst the ZnO does not covalently reacted on the untreated ULTEM® 1000 films. Notably, we demonstrate that two different regimes of growth take place in the oxidized polymer as a function of the photo-exposure time. In particular, the formation of a nanostructured coating of ZnO on the polyetherimide surface is found in the case of short-time photo-exposed polyetherimide (ALD-like regime), whilst an intermixed organic/polymer layer is found on the long-time oxidized films (Vapor Phase Infiltration, VPI-like regime). The photocatalytic activity of the synthesized materials has been tested through the degradation of methylene blue dye in aqueous solution under UV light irradiation, so to give a proof of concept of a possible application of the nano-composites.
- Published
- 2017
22. Intrinsic limits on resolutions in muon- and electron-neutrino charged-current events in the KM3NeT/ORCA detector
- Author
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Adrian-Martinez, S. Ageron, M. Aiello, S. Albert, A. and Ameli, F. Anassontzis, E. G. Andre, M. Androulakis, G. and Anghinolfi, M. Anton, G. Ardid, M. Avgitas, T. and Barbarino, G. Barbarito, E. Baret, B. Barrios-Marti, J. and Belias, A. Berbee, E. van den Berg, A. Bertin, V. and Beurthey, S. van Beveren, V. Beverini, N. Biagi, S. and Biagioni, A. Billault, M. Bondi, M. Bormuth, R. and Bouhadef, B. Bourlis, G. Bourret, S. Boutonnet, C. and Bouwhuis, M. Bozza, C. Bruijn, R. Brunner, J. Buis, E. and Buompane, R. Busto, J. Cacopardo, G. Caillat, L. and Calamai, M. Calvo, D. Capone, A. Caramete, L. Cecchini, S. Celli, S. Champion, C. Cherubini, S. Chiarella, V. and Chiarelli, L. Chiarusi, T. Circella, M. Classen, L. and Cobas, D. Cocimano, R. Coelho, J. A. B. Coleiro, A. and Colonges, S. Coniglione, R. Cordelli, M. Cosquer, A. and Coyle, P. Creusot, A. Cuttone, G. D'Amato, C. D'Amico, A. D'Onofrio, A. De Bonis, G. De Sio, C. Di Palma, I. and Diaz, A. F. Distefano, C. Donzaud, C. Dornic, D. and Dorosti-Hasankiadeh, Q. Drakopoulou, E. Drouhin, D. and Durocher, M. Eberl, T. Eichie, S. van Eijk, D. El Bojaddaini, I. Elsaesser, D. Enzenhofer, A. Favaro, M. and Fermani, P. Ferrara, G. Frascadore, G. Furini, M. Fusco, L. A. Gal, T. Galata, S. Garufi, F. Gay, P. Gebyehu, M. Giacomini, F. Gialanella, L. Giordano, V. Gizani, N. and Gracia, R. Graf, K. Gregoire, T. Grella, G. Grmek, A. Guerzoni, M. Habel, R. Hallmann, S. van Haren, H. and Harissopulos, S. Heid, T. Heijboer, A. Heine, E. Henry, S. Hernandez-Rey, J. J. Hevinga, M. Hofestaedt, J. and Hugon, C. M. F. Illuminati, G. James, C. W. Jansweijer, P. and Jongen, M. de Jong, M. Kadler, M. Kalekin, O. and Kappes, A. Katz, U. F. Keller, P. Kieft, G. Kiessling, D. Koffeman, E. N. Kooijman, P. Kouchner, A. Kreter, M. and Kulikovskiy, V. Lahmann, R. Lamare, P. Larosa, G. and Leisos, A. Leone, F. Leonora, E. Clark, M. Lindsey and Liolios, A. Llorens Alvarez, C. D. Lo Presti, D. Lohner, H. and Lonardo, A. Lotze, M. Loucatos, S. Maccioni, E. and Mannheim, K. Manzali, M. Margiotta, A. Margotti, A. and Marinelli, A. Maris, O. Markou, C. Martinez-Mora, J. A. and Martini, A. Marzaioli, F. Mele, R. Melis, K. W. Michael, T. Migliozzi, P. Migneco, E. Mijakowski, P. Miraglia, A. and Mollo, C. M. Mongelli, M. Morganti, M. Moussa, A. and Musico, P. Musumeci, M. Navas, S. Nicolau, C. A. Olcina, I. Olivetto, C. Orlando, A. Orzelli, A. Pancaldi, G. and Papaikonomou, A. Papaleo, R. Pavalas, G. E. Peek, H. and Pellegrini, G. Pellegrino, C. Perrina, C. Pfutzner, M. and Piattelli, P. Pikounis, K. Pleinert, M. -O. Poma, G. E. and Popa, V. Pradier, T. Pratolongo, F. Puehlhofer, G. and Pulvirenti, S. Quinn, L. Racca, C. Raffaelli, F. and Randazzo, N. Rauch, T. Real, D. Resvanis, L. Reubelt, J. and Riccobene, G. Rossi, C. Rovelli, A. Saldana, M. and Salvadori, I. Samtleben, D. F. E. Garcia, A. Sanchez Losa, A. Sanchez Sanguineti, M. Santangelo, A. Santonocito, D. and Sapienza, P. Schimmel, F. Schmelling, J. Schnabel, J. and Sciacca, V. Sedita, M. Seitz, T. Sgura, I. Simeone, F. and Sipala, V. Spisso, B. Spurio, M. Stavropoulos, G. and Steijger, J. Stellacci, S. M. Stransky, D. Taiuti, M. and Tayalati, Y. Terrasi, F. Tezier, D. Theraube, S. Timmer, P. Tonnis, C. Trasatti, L. Travaglini, R. Trovato, A. and Tsirigotis, A. Tzamarias, S. Tzamariudaki, E. Vallage, B. Van Elewyck, V. Vermeulen, J. Versari, F. Vicini, P. and Viola, S. Vivolo, D. Volkert, M. Wiggers, L. Wilms, J. de Wolf, E. Zachariadou, K. Zani, S. Zornoza, J. D. and Zuniga, J. KM3NeT Collaboration
- Subjects
Physics::Instrumentation and Detectors ,Astrophysics::High Energy Astrophysical Phenomena ,High Energy Physics::Experiment - Abstract
Studying atmospheric neutrino oscillations in the few-GeV range with a multimegaton detector promises to determine the neutrino mass hierarchy. This is the main science goal pursued by the future KM3NeT/ORCA water Cherenkov detector in the Mediterranean Sea. In this paper, the processes that limit the obtainable resolution in both energy and direction in charged-current neutrino events in the ORCA detector are investigated. These processes include the composition of the hadronic fragmentation products, the subsequent particle propagation and the photon-sampling fraction of the detector. GEANT simulations of neutrino interactions in seawater produced by GENIE are used to study the effects in the 1-20 GeV range. It is found that fluctuations in the hadronic cascade in conjunction with the variation of the inelasticity y are most detrimental to the resolutions. The effect of limited photon sampling in the detector is of significantly less importance. These results will therefore also be applicable to similar detectors/media, such as those in ice.
- Published
- 2017
23. Simultaneous determination by NIR spectroscopy of the roasting degree and Arabica/Robusta ratio in roasted and ground coffee
- Author
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Francesco Geobaldo, Elisa Bertone, Alessandro Giraudo, G. Pellegrino, and Alberto Venturello
- Subjects
Multivariate calibration ,010401 analytical chemistry ,Near-infrared spectroscopy ,Organoleptic ,04 agricultural and veterinary sciences ,NIR ,Multi-parameter methods ,040401 food science ,01 natural sciences ,0104 chemical sciences ,Degree (temperature) ,Roasting colour ,Arabica and Robusta coffee ,Chemometrics ,0404 agricultural biotechnology ,Key factors ,Ground coffee ,Screening tool ,Food science ,Food Science ,Biotechnology ,Roasting ,Mathematics - Abstract
The roasting colour of the coffee beans and the varietal composition of the blends are key factors for the development of the sensorial properties of the coffee brew. The former is a critical control parameter for the roasting process and allows to verify quickly the performance of the roasting, being directly related to the desired organoleptic characteristics of the beverage. The varietal composition is a paramount factor for quality, where Arabica species shows a better sensorial profile in comparison to Robusta, with a substantial difference in the selling price. Near infrared spectroscopy associated with chemometrics represents a screening tool when a fast determination of these two coffee parameters is needed. The focus of the work is the elaboration of a unique model for the simultaneous determination of the roasting degree and of Arabica/Robusta ratio. The PLS algorithm was applied and a completely independent external set was used for the validation. A root mean square errors equal to 1.28 A.U. and 4.34% (w/w) was obtained, respectively for the colour and the Arabica content in the blends.
- Published
- 2016
24. A method to stabilise the performance of negatively fed KM3NeT photomultipliers
- Author
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Adrián-Martínez, S. Ageron, M. Aiello, S. Albert, A. Ameli, F. Anassontzis, E.G. Andre, M. Androulakis, G. Anghinolfi, M. Anton, G. Ardid, M. Avgitas, T. Barbarino, G. Barbarito, E. Baret, B. Barrios-Martí, J. Belias, A. Berbee, E. Van Den Berg, A. Bertin, V. Beurthey, S. Van Beveren, V. Beverini, N. Biagi, S. Biagioni, A. Billault, M. Bondì, M. Bormuth, R. Bouhadef, B. Bourlis, G. Bourret, S. Boutonnet, C. Bouwhuis, M. Bozza, C. Bruijn, R. Brunner, J. Buis, E. Buompane, R. Busto, J. Cacopardo, G. Caillat, L. Calamai, M. Calvo, D. Capone, A. Caramete, L. Cecchini, S. Celli, S. Champion, C. Cherubini, S. Chiarella, V. Chiarelli, L. Chiarusi, T. Circella, M. Classen, L. Cobas, D. Cocimano, R. Coelho, J.A.B. Coleiro, A. Colonges, S. Coniglione, R. Cordelli, M. Cosquer, A. Coyle, P. Creusot, A. Cuttone, G. D'Amato, C. D'Amico, A. D'Onofrio, A. De Bonis, G. De Sio, C. Di Capua, F. Di Palma, I. Distefano, C. Donzaud, C. Dornic, D. Dorosti-Hasankiadeh, Q. Drakopoulou, E. Drouhin, D. Durocher, M. Eberl, T. Eichie, S. Van Eijk, D. El Bojaddaini, I. Elsaesser, D. Enzenhöfer, A. Favaro, M. Fermani, P. Ferrara, G. Frascadore, G. Furini, M. Fusco, L.A. Gal, T. Galatà, S. Garufi, F. Gay, P. Gebyehu, M. Giacomini, F. Gialanella, L. Giordano, V. Gizani, N. Gracia, R. Graf, K. Grégoire, T. Grella, G. Grmek, A. Guerzoni, M. Habel, R. Hallmann, S. Van Haren, H. Harissopulos, S. Heid, T. Heijboer, A. Heine, E. Henry, S. Hernández-Rey, J.J. Hevinga, M. Hofestädt, J. Hugon, C.M.F. Illuminati, G. James, C.W. Jansweijer, P. Jongen, M. De Jong, M. Kadler, M. Kalekin, O. Kappes, A. Katz, U.F. Keller, P. Kieft, G. Kießling, D. Koffeman, E.N. Kooijman, P. Kouchner, A. Kreter, M. Kulikovskiy, V. Lahmann, R. Lamare, P. Leisos, A. Leonora, E. Clark, M.L. Liolios, A. Alvarez, C.D.L. Lo Presti, D. Löhner, H. Lonardo, A. Lotze, M. Loucatos, S. Maccioni, E. Mannheim, K. Manzali, M. Margiotta, A. Margotti, A. Marinelli, A. Mariš, O. Markou, C. Martínez-Mora, J.A. Martini, A. Marzaioli, F. Mele, R. Melis, K.W. Michael, T. Migliozzi, P. Migneco, E. Mijakowski, P. Miraglia, A. Mollo, C.M. Mongelli, M. Morganti, M. Moussa, A. Musico, P. Musumeci, M. Nicolau, C.A. Olcina, I. Olivetto, C. Orlando, A. Orzelli, A. Pancaldi, G. Paolucci, A. Papaikonomou, A. Papaleo, R. Pǎvǎlaš, G.E. Peek, H. Pellegrini, G. Pellegrino, C. Perrina, C. Pfutzner, M. Piattelli, P. Pikounis, K. Poma, G.E. Popa, V. Pradier, T. Pratolongo, F. Pühlhofer, G. Pulvirenti, S. Quinn, L. Racca, C. Raffaelli, F. Randazzo, N. Real, D. Resvanis, L. Reubelt, J. Riccobene, G. Rossi, C. Rovelli, A. Saldaña, M. Salvadori, I. Samtleben, D.F.E. Sánchez García, A. Sánchez Losa, A. Sanguineti, M. Santangelo, A. Santonocito, D. Sapienza, P. Schimmel, F. Schmelling, J. Schnabel, J. Sciacca, V. Sedita, M. Seitz, T. Sgura, I. Simeone, F. Sipala, V. Spisso, B. Spurio, M. Stavropoulos, G. Steijger, J. Stellacci, S.M. Stransky, D. Taiuti, M. Tayalati, Y. Terrasi, F. Tézier, D. Theraube, S. Timmer, P. Tönnis, C. Trasatti, L. Travaglini, R. Trovato, A. Tsirigotis, A. Tzamarias, S. Tzamariudaki, E. Vallage, B. Van Elewyck, V. Vermeulen, J. Versari, F. Vicini, P. Viola, S. Vivolo, D. Volkert, M. Wiggers, L. Wilms, J. De Wolf, E. Zachariadou, K. Zani, S. Zornoza, J.D. Zúñiga, J.
- Abstract
The KM3NeT research infrastructure, currently under construction in the Mediterranean Sea, will host neutrino telescopes for the identification of neutrino sources in the Universe and for studies of the neutrino mass hierarchy. These telescopes will house hundreds of thousands of photomultiplier tubes that will have to be operated in a stable and reliable fashion. In this context, the stability of the dark counts has been investigated for photomultiplier tubes with negative high voltage on the photocathode and held in insulating support structures made of 3D printed nylon material. Small gaps between the rigid support structure and the photomultiplier tubes in the presence of electric fields can lead to discharges that produce dark count rates that are highly variable. A solution was found by applying the same insulating varnish as used for the high voltage bases directly to the outside of the photomultiplier tubes. This transparent conformal coating provides a convenient and inexpensive method of insulation. © 2016 IOP Publishing Ltd and Sissa Medialab srl.
- Published
- 2016
25. Incorporating InSAR kinematics into rock glacier inventories: insights from 11 regions worldwide
- Author
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A. Bertone, C. Barboux, X. Bodin, T. Bolch, F. Brardinoni, R. Caduff, H. H. Christiansen, M. M. Darrow, R. Delaloye, B. Etzelmüller, O. Humlum, C. Lambiel, K. S. Lilleøren, V. Mair, G. Pellegrinon, L. Rouyet, L. Ruiz, and T. Strozzi
- Subjects
Environmental sciences ,GE1-350 ,Geology ,QE1-996.5 - Abstract
Rock glaciers are landforms related to permafrost creep that are sensitive to climate variability and change. Their spatial distribution and kinematic behaviour can be critical for managing water resources and geohazards in periglacial areas. Rock glaciers have been inventoried for decades worldwide, often without assessment of their kinematics. The availability of remote sensing data however makes the inclusion of kinematic information potentially feasible, but requires a common methodology in order to create homogeneous inventories. In this context, the International Permafrost Association (IPA) Action Group on rock glacier inventories and kinematics (2018–2023), with the support of the European Space Agency (ESA) Permafrost Climate Change Initiative (CCI) project, is defining standard guidelines for the inclusion of kinematic information within inventories. Here, we demonstrate the feasibility of applying common rules proposed by the Action Group in 11 regions worldwide. Spaceborne interferometric synthetic aperture radar (InSAR) was used to characterise identifiable moving areas related to rock glaciers, applying a manual and a semi-automated approach. Subsequently, these areas were used to assign kinematic information to rock glaciers in existing or newly compiled inventories. More than 5000 moving areas and more than 3600 rock glaciers were classified according to their kinematics. The method and the preliminary results were analysed. We identified drawbacks related to the intrinsic limitations of InSAR and to various applied strategies regarding the integration of non-moving rock glaciers in some investigated regions. This is the first internationally coordinated work that incorporates kinematic attributes within rock glacier inventories at a global scale. The results show the value of designing standardised inventorying procedures for periglacial geomorphology.
- Published
- 2022
- Full Text
- View/download PDF
26. Hypervariable plastid locus variation and intron evolution in the Anacamptis palustris lineage
- Author
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COZZOLINO, SALVATORE, CAFASSO, DONATA, G. Pellegrino, A. Musacchio, A. Widmer, Cozzolino, Salvatore, Cafasso, Donata, G., Pellegrino, A., Musacchio, and A., Widmer
- Published
- 2004
27. Legal liability in bisphosphonate-related osteonecrosis of the jaw
- Author
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Lorenzo Lo Muzio, P. Di Lorenzo, O. Di Fede, Claudio Buccelli, Lucio Lo Russo, Giuseppina Campisi, G. Pellegrino, Domenico Ciavarella, Lo Russo, Lucio, Ciavarella, D, Buccelli, Claudio, Di Fede, O, Campisi, G, Lo Muzio, Lorenzo, Pellegrino, Giacchino, DI LORENZO, Pierpaolo, Lo Russo, L, Buccelli, C, Lo Muzio, L, Pellegrino, G, and Di Lorenzo, P
- Subjects
medicine.medical_specialty ,bisphosphonate, jaw ,Legal liability ,business.industry ,medicine.medical_treatment ,Liability ,Settore MED/50 - Scienze Tecniche Mediche Applicate ,Liability, Legal ,Bisphosphonate ,medicine.disease ,Surgery ,Quality of life (healthcare) ,Settore MED/28 - Malattie Odontostomatologiche ,Malpractice ,medicine ,Humans ,Bisphosphonate-Associated Osteonecrosis of the Jaw ,Causation ,Medical prescription ,Osteonecrosis of the jaw ,Intensive care medicine ,business ,General Dentistry - Abstract
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse reaction that may occur in patients administered with bisphosphonates (BP). This condition can cause high morbidity and hinder quality of life. Its treatment is complex and often unsatisfactory, and prevention strategies may have limited effectiveness, if any. Thus, managing patients treated with BP may result in exposure of the practitioner to legal liability or malpractice claims: legal actions pursuant to BRONJ are reported to be underway on three continents. Nonetheless, the attribution of liability, if any, is a complex process requiring, on the basis of current knowledge, a robust and pragmatic approach to the facts, which must be identified from the point of view of the time, place and individuals involved. This means a comprehensive consideration of the sequence of actions from bisphosphonates prescription to BRONJ occurrence (as well as immediately after, and any action potentially related to its causation or worsening) is required in order to determine if a breach in informing, diagnosing, managing or referring the patient took place, as well as determining if the patient was compliant in attending to prescriptions and follow-up programmes.
- Published
- 2014
28. Recent distribution of Red-legged Partridge Alectoris rufa in Piedmont (North Western Italy): signs of recent spreading
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Tizzani, Paolo, Boano, G., Mosso, M., Pelazza, M., Carolfi, S., Ferra, M., Marletta, N., Pio, G. Pellegrino I., Meneguz, Pier Giuseppe, Silvano, F., Negri, E., and Spanò, S.
- Published
- 2013
29. Coupled fluid flow, heat transfer, phase transformation, stress and deformation numerical model for gas quenching
- Author
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Sabine Denis, F. Chaffotte, J. F. Douce, Jean-Pierre Bellot, F. Gouhinec, J. Maury, Pascal Lamesle, G. Pellegrino, Centre de Recherche Outillages, Matériaux et Procédés (CROMeP), IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
- Subjects
010302 applied physics ,Quenching ,simulation numerique ,chemistry.chemical_element ,Thermodynamics ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Thermal conduction ,01 natural sciences ,Stress (mechanics) ,[SPI]Engineering Sciences [physics] ,Thermal conductivity ,chemistry ,Residual stress ,0103 physical sciences ,Heat transfer ,Fluid dynamics ,General Materials Science ,trempe ,0210 nano-technology ,Helium ,ComputingMilieux_MISCELLANEOUS ,traitement thermique - Abstract
Owing to the growing interest in high-pressure gas quenching, a complete mathematical modelling of this process has been launched with the aim of predicting the microstructural and mechanical state of steel bodies from the quenching operating conditions. The comprehensive numerical modelling combines the calculation of fluid flow and heat transport for the gaseous phase (using Fluent software) and calculation of heat conduction, solid-state phase transformations and residual stresses and distortions in the solid body (using Sysweld software). Our numerical results are compared to the experimental data obtained from a laboratory gas-quenching device set up at the Ecole des Mines d'Albi. Helium- and nitrogen-quenching trials were performed for nickel and 27MnCr5 steel cylinders. The measured gas flow velocities are compared to gas velocities calculated with the Fluent-Sysweld coupling, as well as the temperature evolutions at different locations in the cylinders. On the other hand, the ability of the model for predicting microstructure, residual stresses and deformations is illustrated with the gas quenching of a 60NiCrMo11 steel cylinder.
- Published
- 2008
30. INTERPOSITION OF THE ASCENDING COLON BETWEEN THE KIDNEY AND THE PSOAS MUSCLE: A NORMAL ANATOMIC VARIATION STUDIED BY CT
- Author
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GRASSI, Roberto, A. PINTO, V. NOCERA, M. SCAGLIONE, G. ROSSI, G. PELLEGRINO, Grassi, Roberto, A., Pinto, V., Nocera, M., Scaglione, G., Rossi, and G., Pellegrino
- Published
- 1997
31. Bond Lengths and Elasticity in Strained-Layer Semiconductors
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K. E. Miyano, Joseph C. Woicik, and Joseph G. Pellegrino
- Subjects
Condensed matter physics ,Extended X-ray absorption fine structure ,Chemistry ,business.industry ,Condensed Matter::Other ,General Physics and Astronomy ,Mineralogy ,Elasticity (physics) ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Bond length ,Standing wave ,Condensed Matter::Materials Science ,Semiconductor ,[PHYS.HIST]Physics [physics]/Physics archives ,Monolayer ,business - Abstract
The x-ray standing wave (XSW) and extended x-ray absorption fine structure (EXAFS) techniques have determined the strain and bond distortions in an InAs monolayer embedded in GaAs(001). A unifying picture of bond lengths and elasticity in strained-layer semiconductors is presented.
- Published
- 1997
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32. Different levels of inbreeding depression between outcrossing and selfing Serapias species.
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F. Bellusci, G. Pellegrino, and A. Musacchio
- Subjects
- *
INBREEDING , *REPRODUCTION , *PLANT embryology , *EMBRYOLOGY - Abstract
Abstract  We quantified inbreeding depression for fruit production, embryo vitality and seed germination in three deceptive orchids, Serapias vomeracea, S. cordigera and S. parviflora, which do not provide any reward to their pollinators, and are predicted to experience high outcrossing. Of the three species examined only S. parviflora was autonomously selfing. Both S. vomeracea and S. cordigera showed highly significant differences in fitness between selfed and outcrossed progenies, resulting in high levels of inbreeding depression, which increased in magnitude from seed set to seed germination. Inbreeding depression may promote outcrossing in Serapias by acting as a post-pollination barrier to selfing. Cumulative inbreeding depression across three stages in S. parviflora was lower that in both outcrossing species. The large difference in germination between selfed and outcrossed seeds is an important issue in conservation biology. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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33. Enhanced sensitivity in non-enzymatic glucose detection by improved growth kinetics of Ni-based nanostructures.
- Author
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M Urso, G Pellegrino, V Strano, E Bruno, F Priolo, and S Mirabella
- Subjects
- *
GLUCOSE , *NICKEL alloys , *NANOSTRUCTURES - Abstract
Ni-based nanostructures are attractive catalytic materials for many electrochemical applications, among which are non-enzymatic sensing, charge storage, and water splitting. In this work, we clarify the synthesis kinetics of Ni(OH)2/NiOOH nanowalls grown by chemical bath deposition at room temperature and at 50 °C. We applied the results to non-enzymatic glucose sensing, reaching a highest sensitivity of 31 mA cm−2mM−1. Using scanning electron microscopy, x-ray diffraction analysis and Rutherford backscattering spectrometry we found that the growth occurs through two regimes: first, a quick random growth leading to disordered sheets of Ni oxy-hydroxide, followed by a slower growth of well-aligned sheets of Ni hydroxide. A high growth temperature (50 °C), leading mainly to well-aligned sheets, offers superior electrochemical properties in terms of charge storage, charge carrier transport and catalytic action, as confirmed by cyclic voltammetry and electrochemical impedance spectroscopy analyses. The reported results on the optimization and application of low-cost synthesis of these Ni-based nanostructures have a large potential for application in catalysis, (bio)sensing, and supercapacitors areas. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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34. A case-control study of phosphodiesterase-5 inhibitor use and Alzheimer's disease and related dementias among male and female patients aged 65 years and older supporting the need for a phase III clinical trial.
- Author
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David S Henry and Richard G Pellegrino
- Subjects
Medicine ,Science - Abstract
BackgroundPhosphodiesterase-5 inhibitors (PDE5i) have been evaluated as a novel treatment for Alzheimer's disease and related dementias (ADRD), but two recent cohort studies have offered opposing conclusions.MethodsWe performed an unmatched case-control study using electronic medical records from a large healthcare system to evaluate the association of PDE5i use and ADRD in patients ≥65 years old.ResultsOdds of PDE5i exposure were 64.2%, 55.7%, and 54.0% lower in patients with ADRD than controls among populations with erectile dysfunction, benign prostatic hyperplasia, and pulmonary hypertension, respectively. We observed odds ratios less than unity among males and females and with exposure to the PDE5i sildenafil (Viagra®) and tadalafil (Cialis®). We also evaluated the odds of exposure to two other common treatments for pulmonary hypertension: endothelin receptor antagonists (ERA) and calcium channel blockers (CCB). The odds of ERA exposure were 63.2% lower, but the odds of CCB exposure were 30.7% higher, in patients with ADRD than controls among the population with pulmonary hypertension.ConclusionsOur results reconcile the opposing conclusions from the previous observational studies and support further research into using PDE5i for prevention and treatment of ADRD.
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- 2023
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35. Paroxysmal Explosions, Lava Fountains and Ash Plumes at Etna Volcano: Eruptive Processes and Hazard Implications
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Sonia Calvari, Flavio Cannavò, Alessandro Bonaccorso, Letizia Spampinato, and Alessandra G. Pellegrino
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Etna volcano ,paroxysmal explosive activity ,lava fountains ,ash plume ,thermal cameras ,Science - Abstract
Lava fountains have a major impact on the local population since they cause ash plumes that spread several kilometers above and hundreds of kilometers away from the crater. Ash fallout is responsible for disrupting airports and traffic on the motorways well beyond the area of the volcano itself, as well as affecting the stability of buildings and causing public health issues. It is thus a primary scientific target to forecast the impact of this activity on local communities on the basis of parameters recorded by the monitoring network. Between 2011 and 2015, 49 paroxysmal explosive episodes occurred at two of Mt Etna's five summit craters: the New South-East Crater (NSEC) and the Voragine (VOR). In this paper, we examine the features of the 40 episodes occurring at the NSEC during 2011–2013, and of the 4 events at VOR in December 2015. We study these paroxysms using geophysical monitoring data, characterize the episodes, and analyse all available data statistically. Our main results are two empirical relationships allowing us to forecast the maximum elevation of the ash plume from the average height of the lava fountain, useful for hazard assessment and risk mitigation. For Etna, and using the examples described in this paper, we can infer that wind speed 10 m s−1 is normally associated with weak plumes, bent-over along the wind direction and reaching lower elevations.
- Published
- 2018
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36. Post-transplant lymphoproliferative disorder (PTLD) in a gilt
- Author
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TURA G., PELLEGRINO V., AVALLONE G., BARONE F., BACCI M. L., VILLA R., SPADARI A., VENTRELLA D., DONDI F., CORRADETTI V., LA MANNA G., SARLI G., Comitato Scientifico SISVET/AIPVET, Comitato Scientifico SISVET, and TURA G., PELLEGRINO V., AVALLONE G., BARONE F., BACCI M.L., VILLA R., SPADARI A., VENTRELLA D., DONDI F., CORRADETTI V., LA MANNA G., SARLI G.
- Subjects
Trasplant, Lymphoproliferative disorder, Swine - Published
- 2018
37. Canine smooth muscle tumours of soft tissue: a series of 23 cases
- Author
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Cinzia Benazzi, Valeria Pellegrino, Giancarlo Avallone, Giuseppe Sarli, M. Tecilla, Paola Roccabianca, and AVALLONE G., PELLEGRINO V., ROCCABIANCA P., TECILLA M., BENAZZI C., SARLI G.
- Subjects
body regions ,General Veterinary ,Smooth muscle ,Series (mathematics) ,business.industry ,Medicine ,Soft tissue ,Anatomy ,dog, smooth muscle, tumour ,business ,Pathology and Forensic Medicine - Abstract
Introduction: Canine smooth muscle tumours (SMTs) occur mostly in the gastrointestinal and female genital tracts, while soft tissue SMTs are reported rarely. In man, soft tissue leiomyomas are prevalent in cutaneous and subcutaneous tissues, while leiomyosarcomas develop more frequently in retroperitoneal, pelvic or intra-abdominal tissues in women. This study describes the clinicopathological features of canine soft tissue SMTs. Materials andMethods: Cases were collected retrospectively, clinical data retrieved and diagnoses confirmed by re-evaluation of HE-stained slides and by immunohistochemistry. Mitotic count, atypia, necrosis and histological grade were assessed.Oestrogen (OR) and progesterone (PR) receptor expression was evaluated immunohistochemically. Results: Twenty-three cases were collected: eight leiomyomas and 15 leiomyosarcomas (seven grade I, six grade II, two grade III). Thirteen dogs were female (5 neutered) and 10 male (one neutered). Eleven SMTs were subcutaneous (five in the limbs, four perineal, two perianal); five were pelvic, five retroperitoneal, one intra-abdominal and one in the oral cavity. Seven of 10 retroperitoneal/pelvic SMTs were found in female (70%) and three in male dogs. Two perineal leiomyosarcomas and one pelvic leiomyoma expressed OR. One retroperitoneal leiomyoma expressed PR. All OR- and/or PR-positive SMTs occurred in intact females. Conclusions: Canine soft tissue SMTs were more frequently subcutaneous (limbs and perianal/perineal region) and retroperitoneal (including pelvic). Retroperitoneal SMTs were more common in female dogs, paralleling human SMTs. OR and PR expression in some cases suggests the existence of a distinct subset of canine soft tissue SMTs that may display different behaviour, to be assessed in future studies.
- Published
- 2018
38. Parasite Users? The Volunteer Mapping of Cycling Infrastructures
- Author
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Denis, Jérôme, Pontille, David, Laboratoire Traitement et Communication de l'Information (LTCI), Télécom ParisTech-Institut Mines-Télécom [Paris] (IMT)-Centre National de la Recherche Scientifique (CNRS), Centre de Sociologie de l'Innovation i3 (CSI i3), MINES ParisTech - École nationale supérieure des mines de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), and A. Mongili, G. Pellegrino
- Subjects
[SHS.SOCIO]Humanities and Social Sciences/Sociology ,infrastructure ,Openstreetmap ,GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries) ,Volunteered geographic information ,Users ,Bicycling - Abstract
International audience; This chapter aims at understanding the place of users in the online discussions between Openstreetmap contributors who map cycling infrastructures. Drawing on an analysis of the mailing list of the French forum of Openstreetmap, we show that contributors deal with different kinds of users' instantiations. We describe how these contributors try to avoid any attachement to one or another category of users, which would threaten their ideal of "universality".
- Published
- 2014
39. Organizations as boundary objects: organizing business between research and the market
- Author
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Miele, Francesco, Alessandro Mongili Giuseppina Pellegrino, A. Mongili G. Pellegrino, Miele, F., and Miele, Francesco
- Published
- 2014
40. The definition of chemical contaminants in food: Ambiguity and consequences.
- Author
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Rietjens IMCM, Pascale M, Pellegrino G, Ribera D, Venâncio A, Wang D, and Korzeniowski K
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- Humans, Risk Assessment, Animals, Food Contamination analysis
- Abstract
Consumers may be exposed via foods to a diverse range of substances that could be considered as contaminants. However, it is not always straightforward to understand the definition of a 'contaminant'. The present review evaluates how various categories of food-relevant substances are considered in terms of being 'contaminants'. To this end these categories of food borne constituents are evaluated against the various criteria encountered in the available definitions of a food contaminant, including unintentional presence, harmful, existence of regulatory limits, and stakeholder perception. The categories of chemicals considered include: phytotoxins, mycotoxins, (heavy) metals, persistent organic pollutants (POPs), processing aids, process related contaminants, food contact materials (FCMs), pesticides and veterinary drugs. The evaluation revealed that usage of the term appears complex, and may differ between stakeholders. A common proposed definition of the term 'contaminant' could be 'a substance considered to require control measures due to the unacceptability of its context within a food'. Use of a dimension of harm results in equivocal outcomes because risk depends on the level of exposure. As the term 'contaminant' has influence on risk management including public policy, the motivations for applying the term should be subject to more detailed analysis and understanding., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Rietjens Ivonne and Wang Danlei were paid an honoraria to complete the work. Konrad Korzeniowski is a full-time employee of ILSI Europe., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2025
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41. Zygomatic implants for rehabilitation of patients with oncologic and congenital defects: A case series.
- Author
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Pellegrino G, Tarsitano A, Ratti S, Ceccariglia F, Gessaroli M, Barausse C, Tayeb S, and Felice P
- Abstract
This case series aimed to assess the clinical outcomes of oncologic patients rehabilitated with a zygomatic implant-supported prosthesis. Ten oncologic patients who underwent upper jaw resections due to cancer were enrolled in the study. Zygomatic implants were utilized for rehabilitation according to specified inclusion criteria. Surgical and prosthetic procedures were standardized, and implant and prosthetic survival rates, along with complications, were evaluated. The study cohort comprised 10 patients with a mean age of 66.5 years. A total of 35 implants were placed, with a survival rate of 94.29% at the mean follow-up of 5.78 years. Biological complications affected 40% of patients, while prosthetic complications occurred in 40% of patients, necessitating modifications but with no outright failures. Zygomatic implants offer a viable solution for oncologic patient rehabilitation, particularly in cases where bone grafting is contraindicated or impractical. However, they present medium-to long-term complications that warrant careful consideration. Future research should focus on larger studies and meta-analyses to provide more robust evidence., Competing Interests: Declaration of competing interest None of the authors report any conflict of interest., (Copyright © 2024 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2025
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42. Anatomy Education and Training Methods in Oral Surgery and Dental Implantology: A Narrative Review.
- Author
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Barausse C, Felice P, Pistilli R, Pellegrino G, Bonifazi L, Tayeb S, Neri I, Koufi FD, Fazio A, Marvi MV, Manzoli L, and Ratti S
- Abstract
Background: Oral and implant surgery represent highly specialized fields within dentistry that require a deep understanding of complex anatomical structures, together with practical hands-on experience. The present review examines common trends in oral and implant surgery training, focusing on how traditional methods like donated body dissection coexist with different and modern educational tools, and highlights the pros and cons of the different approaches in order to optimize training outcomes. Methods: A systematic literature search was carried out using the databases PubMed and Cochrane Library including the last 10 years of published articles about training in oral surgery and implantology. Starting from a total of 1319 studies, 47 were included to be carefully evaluated, and 20 studies were finally selected for this narrative review. The studies utilize methodologies such as randomized controlled trials (RCTs), cross-sectional surveys, case-control studies, and systematic reviews. The results were thematically organized, highlighting key quantitative outcomes and drawing connections between the different educational approaches. Results: From the narrative review, it emerged that oral and implant surgery training requires a careful balance between traditional methods, such as donated human body dissection, and modern technological advancements like virtual simulations and synthetic models. While animal and synthetic models have specific uses, their application remains limited in replicating the full complexity of human anatomy. These last technologies offer flexibility and expanded access to education but do not substitute for the hands-on experience gained through donated human body dissection. Conclusions: As educational institutions continue to evolve their training programs, ensuring access to human body dissection remains of paramount importance. Combining the strengths of both traditional and modern approaches may help optimize oral and implant surgery education, enhancing student preparedness without overlooking the critical value of direct anatomical experience.
- Published
- 2024
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43. Percutaneous microwave ablation of HCC: comparison between 100 and 150 W technology systems.
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Lanza C, Angileri SA, Biondetti P, Coppola A, Ricapito F, Ascenti V, Amato G, Pellegrino G, Sciacqua LV, Vanzulli A, Carriero S, Venturini M, Ierardi AM, and Carrafiello G
- Subjects
- Humans, Male, Female, Aged, Retrospective Studies, Middle Aged, Treatment Outcome, Tomography, X-Ray Computed, Ablation Techniques methods, Catheter Ablation methods, Postoperative Complications, Microwaves therapeutic use, Carcinoma, Hepatocellular surgery, Carcinoma, Hepatocellular diagnostic imaging, Liver Neoplasms surgery, Liver Neoplasms diagnostic imaging
- Abstract
Purpose: To evaluate the differences in efficacy and safety between the 100 and 150 W percutaneous microwave ablation (MWA) systems in the treatment of hepatocellular carcinoma (HCC)., Methods: We retrospectively reviewed all patients who underwent percutaneous MWA (Emprint™ HP Ablation System, Medtronic) between January 2021 and May 2023. We divided the cohort into two groups: Group 1, treated with MWA at 100 W power system, and Group 2, treated with 150 W one. Effectiveness was defined as the absence of residual disease at 1-month CT follow-up; safety was defined as the absence of grade II-VI complications., Results: A total of 135 HCC nodules were treated with MWA in 87 patients with a median age of 66 ± 10 years: 76 procedures in 42 patients were carried out in group 1, while 59 procedures in 45 patients in group 2. Cases treated with 150 W had a shorter ablation time (p: 0.002; mean 227.37 ± 92.5 vs 180.51 ± 75.6 s (100 vs 150 W)) and a larger ablation volume (p 0.008; mean 13,920.0 ± 10,723.2 vs 21,241.4 ± 18,374.7 mm
3 (100 vs 150 W)), and a major effectiveness at 1-month CT follow-up (p: 0.013). A higher rate of complications (grade II and III) was observed in Group 2 (p < 0.001)., Conclusions: In conclusion, these preliminary results showed a good correlation between intended-to-treat area and ablation volume and intended-to-treat area and ablation time for both Groups. A minor ablation time, and major ablation volume, but also a higher incidence of complications was observed in 150 W Group., Competing Interests: Declarations. Conflict of interest: Serena Carriero is an editor in this journal. The other authors have no conflict of interest to declare that are relevant to the content of this article. Human participants or animals: This retrospective chart review study involving human participants was in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent: Informed written consent was obtained from all individual participants included in the study., (© 2024. Italian Society of Medical Radiology.)- Published
- 2024
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44. Pollinator diversity of the food-deceptive orchids in southern Italy.
- Author
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Carlomagno F, Lanzino M, Mendicino F, Bonacci T, and Pellegrino G
- Subjects
- Animals, Italy, Bees physiology, Biodiversity, Insecta physiology, Coleoptera physiology, Diptera physiology, Flowers physiology, Pollination physiology, Orchidaceae physiology
- Abstract
The orchid family is renowned for its enormous diversity in pollination biology. Many orchid species use deception to attract pollinators, and the main strategy in terrestrial orchids is food deception. Food-deceptive orchids usually show a low number of pollinator visitations, making field observations of pollinators difficult. In this study visual census, pollinator capture and molecular analysis of pollinaria found on caught insects allowed us to obtain information on species composition of orchid pollinators. A total of 321 insects were caught; most specimens were hymenopterans (Apis mellifera, Bombus ruderatus and Eucera rufa) and coleopterans (Tropinota hirta and T. squalida). The identity of species to which pollinaria found on the insect's body belonged was confirmed by molecular analysis. Moreover, some individuals of Billaea lata (Tachinidae, Diptera) were captured and photographed with the pollinaria on their head. Two new and important results emerged clearly in this work: a dipteran, Billaea lata, pollinator of Anacamptis pyramidalis, and two beetles in the genus Tropinota are pollinators of Orchis italica. Our results confirm that generalized food-deceptive orchids of the genera Orchis and Anacamptis show weak pollinator specificity., (© 2024 The Author(s). Plant Biology published by John Wiley & Sons Ltd on behalf of German Society for Plant Sciences, Royal Botanical Society of the Netherlands.)
- Published
- 2024
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45. Pharmacological Treatment of Fibromyalgia Syndrome: A Practice-Based Review.
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Giorgi V, Sarzi-Puttini P, Pellegrino G, Sirotti S, Atzeni F, Alciati A, Torta R, Varrassi G, Fornasari D, Coaccioli S, and Bongiovanni SF
- Subjects
- Humans, Antidepressive Agents therapeutic use, Anticonvulsants therapeutic use, Fibromyalgia drug therapy, Analgesics therapeutic use
- Abstract
Purpose of Review: Fibromyalgia Syndrome (FMS) is a complex chronic pain condition characterized by widespread musculoskeletal pain and numerous other debilitating symptoms. The purpose of this review is to provide a comprehensive overview, based on everyday clinical practice, of the drugs presently employed in the treatment of FMS., Recent Findings: The treatment of FMS is based on a multimodal approach, with pharmacologic treatment being an essential pillar. The drugs used include tricyclic antidepressants, serotonin and noradrenaline reuptake inhibitors, other antidepressants, anticonvulsants, myorelaxants, and analgesics. The effectiveness of these medications varies, and the choice of drug often depends on the specific symptoms presented by the patient. Many drugs tend to either address only some domains of the complex FMS symptomatology or have a limited effect on pain. Each treatment option comes with potential side effects and risks that necessitate careful consideration. It may be beneficial to divide patients into clinical subpopulations, such as FMS with comorbid depression, for more effective treatment. Despite the complexities and challenges, the pharmacological treatment remains a crucial part for the management of FMS. This review aims to guide clinicians in prescribing pharmacological treatment to individuals with FMS., Competing Interests: Compliance with Ethical Standards. Conflict of Interest: VG received funding from Dompè farmaceutici in the last 6 months. The other authors declare no competing interests. Human and Animal Rights: This article does not contain any studies with human or animal subjects performed by any of the authors., (© 2024. The Author(s).)
- Published
- 2024
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46. Four-mm-short implants in the rehabilitation of posterior atrophic jaws: A retrospective study on 212 patients with a mean follow-up of 8.02 years.
- Author
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Barausse C, Pistilli R, Bonifazi L, Tayeb S, Pellegrino G, Ravidà A, and Felice P
- Subjects
- Humans, Male, Female, Retrospective Studies, Middle Aged, Follow-Up Studies, Atrophy, Aged, Dental Implantation, Endosseous methods, Adult, Dental Prosthesis Design, Treatment Outcome, Dental Implants, Dental Restoration Failure, Alveolar Bone Loss
- Abstract
Objective: This study aimed to assess clinical efficacy of 4-mm-short implants in patients with posterior severe vertical bone atrophy in the medium- and long-term follow-up., Materials and Methods: Patients rehabilitated with 4-mm-short implants in the posterior atrophic jaws, with a minimum follow-up of 3 years post-loading, were included in the study. Data were collected for eligible patients, and marginal bone loss (MBL) for each implant was evaluated. The research outcomes were implant failure, MBL and complications., Results: A total of 212 patients with 496 implants were included, resulting in a mean follow-up of 8.02 ± 2.17 years. The implant survival rate was 95.36% (95% CI: 93.12%-97.04%). More implant failures were observed in the maxilla (p = .02) and fewer failures were observed in patients undergoing more number of hygienic sessions per year (p < .001). The average MBL after 1-year-loading was 0.47 mm, increasing to 0.59 mm after 10 years; after 3 years no statistically significant increase in MBL was observed. Maxillary implants showed greater bone loss than mandibular ones (p < .001). More frequent professional oral hygiene sessions per year resulted being related with reduced MBL (p < .001)., Conclusions: Four-mm-short implants showed high survival rates with an up to 10-year follow-up. Their use can offer a fixed prosthetic solution for patients with posterior vertical bone atrophy, minimizing surgical invasiveness, rehabilitative times and costs., (© 2024 The Author(s). Clinical Oral Implants Research published by John Wiley & Sons Ltd.)
- Published
- 2024
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47. The clinical and microbiological efficacy of a zinc-citrate/hydroxyapatite/potassium-citrate containing toothpaste: a double-blind randomized controlled clinical trial.
- Author
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Josic U, Maravic T, Mazzitelli C, Rinaldi L, D'Alessandro C, D'Urso D, Pellegrino G, Mazzoni A, and Breschi L
- Subjects
- Humans, Female, Double-Blind Method, Male, Adult, Patient Satisfaction, Dentin Sensitivity, Saliva microbiology, Surveys and Questionnaires, Periodontal Index, Gingivitis microbiology, Gingivitis prevention & control, Citrates, Dental Plaque microbiology, Treatment Outcome, Zinc Compounds therapeutic use, Dental Plaque Index, Middle Aged, Toothpastes therapeutic use, Durapatite, Streptococcus mutans drug effects, Fluorides therapeutic use, Citric Acid pharmacology, Potassium Citrate therapeutic use
- Abstract
Objectives: To evaluate the antibacterial efficacy of two fluoride-containing (1450 ppm F) toothpastes with or without zinc-citrate (ZCT), hydroxyapatite (HAP) and potassium-citrate (KCit); to assess and compare their clinical effects in terms of tooth sensitivity, plaque accumulation and gingivitis, as well as patients' satisfaction., Materials and Methods: Healthy, adult patients were selected and randomly assigned to two groups (n = 50): Experimental: ZCT-, HAP-, KCit- and fluoride-containing toothpaste; Control: fluoride-containing toothpaste. Salivary counts of Streptococcus mutans (S. mutans), plaque and gingival index, as well as clinically diagnosed sensitivity were recorded at baseline, and after 4 weeks. A custom-made questionnaire was used to assess patients' self-reported sensitivity (baseline and after 4 weeks) and overall satisfaction with the tested toothpastes. Data were statistically analyzed (α = 0.05)., Results: After 4 weeks, a statistically significant salivary reduction of S. mutans was observed in both groups (p = 0.001). Furthermore, the percentage of S. mutans decrease was significantly higher in Experimental group (p = 0.014). There were no statistically significant differences between the groups in terms of plaque and gingival index (p > 0.05). After 4 weeks, the self-reported tooth sensitivity was lower in Experimental group (p < 0.001)., Conclusions: Both toothpastes showed good antimicrobial effect after 4 weeks; however, the toothpaste containing ZCT, HAP, KCit and fluoride was found to be more effective in reducing the salivary counts of S. mutans than the product containing fluoride alone., Clinical Relevance: Toothpaste containing ZCT, HAP, KCit and fluoride can be recommended for patients at risk for developing caries and may also be beneficial for individuals experiencing dental sensitivity., Competing Interests: Declarations. Ethical approval: The study protocol was reviewed and approved by the University of Bologna Ethics Committee (793/2022/SPER/AUSLBO). Informed consent: A written informed consent was obtained from patients before their enrollment in the study. Competing interests: The authors declare no competing interests., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
48. Zygomatic implants in the rehabilitation of severe maxillary atrophy: A retrospective study of 274 zygomatic implants with a mean follow-up period of 7.5 years.
- Author
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Felice P, Bonifazi L, Pistilli R, Trevisiol L, Pellegrino G, Nocini PF, Barausse C, Tayeb S, Bersani M, and D'Agostino A
- Subjects
- Humans, Retrospective Studies, Male, Female, Middle Aged, Follow-Up Studies, Aged, Adult, Treatment Outcome, Dental Implantation, Endosseous methods, Dental Restoration Failure, Alveolar Bone Loss pathology, Zygoma surgery, Zygoma pathology, Maxilla surgery, Maxilla pathology, Dental Implants adverse effects, Atrophy
- Abstract
Purpose: Zygomatic implants are considered one of the last options for the rehabilitation of severe maxillary atrophy when standard implants cannot be placed. They offer several advantages but can also present complications. This study aimed to investigate the long-term clinical and radiographic outcomes of zygomatic implant placement., Materials and Methods: A retrospective chart review was conducted, and the inclusion criteria consisted of patients previously treated with zygomatic implants who had Class V or VI maxillary bone atrophy according to Cawood and Howell, and with a minimum follow-up period of 2 years after prosthetic loading. Outcome measures included implant and prosthesis survival rate, biological and biomechanical complications, and Lund-Mackay staging score before and after implant placement., Results: The study included 78 patients who received a total of 274 zygomatic implants. The mean follow-up period was 90.4 ± 26.0 months. Seventeen implant failures occurred, resulting in a survival rate of 93.8%, with a statistically significant negative correlation with smoking habits (P = 0.049), anchorage to the two zygomatic bone cortices (bicorticality) (P 0.001) and soft tissue complications (P 0.001). The prosthetic success rate was 92.3%. A statistically significant increase in maxillary sinus radiopacity was recorded when comparing the situation before and after surgery (P 0.001), and the intrasinus pathway had a statistically significant influence on that increase (P = 0.003)., Conclusions: Zygomatic implants utilised for rehabilitating patients with severe maxillary atrophy have shown favourable outcomes. Nonetheless, owing to potential complications, strict case selection is necessary, combined with regular recall visits and proper oral hygiene maintenance. Furthermore, this type of surgery necessitates specialised training and expertise on the part of the practitioner.
- Published
- 2024
49. Anatomical Measurements of the Malar Bone for Safe Zygomatic Implant Placement: A Study on Donated Bodies.
- Author
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Barausse C, Felice P, Pistilli R, Pellegrino G, Bonifazi L, Tayeb S, Fazio A, Marvi MV, Manzoli L, and Ratti S
- Abstract
Background : The malar bone provides an anchorage point for zygomatic implants, avoiding invasive reconstructive surgeries in the fixed rehabilitation of fully edentulous and severely atrophic maxillae. The limited bone volume, however, requires precise implant placement to prevent complications related to nearby anatomical structures. This observational cross-sectional study aims to measure the malar and zygomatic arch bones and their distances from critical anatomical landmarks to guide surgeons in safe zygomatic implant placement. Methods : Dissections were performed bilaterally on 29 heads from human donated bodies in a cross-sectional observational study. Key landmarks evaluated include the infraorbital foramen (IF), pyriform nasal aperture (PNA), infraorbital margin (IM), zygomaticofacial foramen (ZFF), anterior end (A), and the most protruding point of the zygomatic arch (B). Measurements included IF-PNA, IF-IM, IF-ZFF, ZFF-IM, A-B, and orbital floor depth (OFD). Results : Significant findings showed IF-PNA was greater in males (18.66 ± 2.63 mm, p = 0.001), and IF-ZFF varied between sides (26.72 ± 8.7 mm, p = 0.002). ZFF-IM was larger in males (7.43 ± 2.09 mm, p < 0.001). Heights and thicknesses were also assessed, with significant side differences observed. Conclusions : These findings underscore the importance of understanding precise anatomical distances for successful implant placement. The study provides essential data to enhance surgical planning and training, ensuring safer procedures and minimizing the risk of complications.
- Published
- 2024
- Full Text
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50. Coffee and mineral oil hydrocarbons: potential dietary intake.
- Author
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Theurillat V, Dubois M, XueFeng D, Pellegrino G, and Lamberti G
- Subjects
- Humans, Food Contamination analysis, Dietary Exposure analysis, Coffee chemistry, Mineral Oil analysis, Mineral Oil chemistry, Hydrocarbons analysis, Hydrocarbons chemistry
- Abstract
Levels of mineral oil hydrocarbons were measured in a large range of green and roasted coffee beans or ground powder. To better understand the consumer exposure to mineral oil hydrocarbons, the transfer to the brewed coffee was assessed under three different preparations. As a result, less than 5% of mineral oil hydrocarbons were transferred to the cup. With this low transfer rate, the coffee contribution to the mineral oils daily intake can be assessed to be very low, below 0.8% of the total exposure.
- Published
- 2024
- Full Text
- View/download PDF
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