Search

We also had come up in the profession socialized to the idea that an article of questionable presentational quality ought to get a round of reviews, even if the review led to a rejection - mentoring the author through the review process. Confronted with a poorly written or poorly developed article, many potential referees just "swipe left" and take a pass on an unattractive article. Or, worst yet, we would use up a dozen or more referee requests with no acceptances while also tying up an article for months only to then decline it with a written desk review by the editors. Maybe we could gain insight into an article when the peer review process did not work when a nontrivial number of potential referees decided not to read an article. [Extracted from the article]

Awareness and enforcement of guidelines for publishing industry-sponsored medical research among publication professionals: the Global Publication Survey. Patient involvement in preparing health research peer-reviewed publications or results summaries: a systematic review and evidence-based recommendations. Patient involvement in preparing health research peer-reviewed publications or results summaries: a systematic review and evidence-based recommendations. [Extracted from the article]

An introduction is presented in which editor discusses various articles within the issue on topics including bonds in California to finance homeowner purchases of solar systems; evolution of maritime technology in the Arabian Gulf and development of blockchain.

The studies related to the structural and functional roles of the conserved polar residues in the N- and C-terminal transmembrane helices of human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) are described. The data obtained proposed a model for putative hydrogen bond interactions of the conserved polar residues in the transmembrane domain of native, oligomeric NTPDase3 which are critical for proper protein expression, full enzymatic activity, and susceptibility to membrane perturbations.

Using content analysis and original survey data, we investigated the news coverage and consequences of Donald Trump's "rigged-election" claims during the 2016 presidential election. We added to previous literature by showing that the effects of such claims were highly contingent on individual partisan affiliation. Republicans and Independents who believed that the elections were rigged via voter fraud or media bias were more likely to report that they intended to vote or had already voted. Democrats and Independents who believed that Hillary Clinton would benefit from voter fraud or media bias were more likely to vote for Donald Trump. [ABSTRACT FROM AUTHOR]

Abstract: Nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) is a cell surface, membrane-bound enzyme that hydrolyzes extracellular nucleotides, thereby modulating purinergic signaling. An alternatively spliced variant of NTPDase3 was obtained and analyzed. This alternatively spliced variant, termed “NTPDase3β”, is produced through the use of an alternative terminal exon (exon 11) in place of the terminal exon (exon 12) in the full-length NTPDase3, now termed “NTPDase3α”. This results in an expressed protein lacking the C-terminal cytoplasmic sequence, the C-terminal transmembrane helix, and apyrase conserved region 5. The cDNA encoding this truncated splice variant was detected in a human lung library by PCR. Like the full-length NTPDase3α, the alternatively spliced NTPDase3β was expressed in COS cells after transfection, but only the full-length NTPDase3α is enzymatically active and properly trafficked to the plasma membrane. However, when the truncated NTPDase3β was co-transfected with full-length NTPDase3α, there was a significant reduction in the amount of NTPDase3α that was properly processed and trafficked to the plasma membrane as active enzyme, indicating that the truncated form interferes with normal biosynthetic processing of the full-length enzyme. This suggests a role for the NTPDase3β variant in the regulation of NTPDase3 nucleotidase activity, and therefore the control of purinergic signaling, in those cells and tissues expressing both NTPDase3α and NTPDase3β. [Copyright &y& Elsevier]

An introduction is presented in which the editor discusses several articles published within issue on topics related to gerrymandering.