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2 results on '"Gauthier Decool"'

1. Efficacy of Tyrosine Kinase Inhibitor Therapy in a Chemotherapy-refractory B-cell Precursor Acute Lymphoblastic Leukemia With ZC3HAV1-ABL2 Fusion

Author

Gauthier Decool, Carine Domenech, Nathalie Grardel, Adriana Plesa, Imelda Raczkiewicz, Benoit Ducourneau, Philippe Ruminy, Marie-Pierre Pages, Sandrine Girard, Laurène Fenwarth, Claude Preudhomme, Yves Bertrand, and Nicolas Duployez

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2019
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2. Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia

Author

Guillaume Grzych, Catherine Roche-Lestienne, Claude Preudhomme, Gauthier Decool, Nicolas Duployez, Elise Boudry-Labis, Wadih Abou Chahla, and Nathalie Grardel

Subjects
Genetics, Poor prognosis, medicine.medical_specialty, RUNX1, business.industry, BCP-ALL, Cytogenetics, General Medicine, Case Reports, cytogenetics, Molecular cytogenetics, SNP-array, chemistry.chemical_compound, Pediatric Acute Lymphoblastic Leukemia, chemistry, Cancer research, medicine, SNP, Chromosome 21, business, SNP array, iAMP21
Abstract

Key Clinical Message Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with poor prognosis that should be investigated in routine practice. Single-nucleotide polymorphism (SNP)-array provides a useful method to detect such cases showing a highly characteristic profile.

Published
2015

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