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9 results on '"Giaquinto G"'

1. Long-term follow-up of HIV-seropositive children

Author

Italian Register for HIV Infection in Children Tovo, Martino, De, Gabiano, M, Galli, C, L, Partecipants:, Ferraris, Giaquinto, G, Casteili, C, Garetto, G, Vierucci, S, Marchisio, A, Zuccotti, P, Fundaro, Gv, Duse, C, Caselli, M, D, Maria, De, Plebani, A, Timpano, A, Lanari, C, Stegagno, M, Ruggeri, M, Gotta, M, Lipreri, G, Cellini, L, Osimani, M, Loriano, P, Benaglia, D, G, Mattia, De, Forni, D, Romano, Gl, Antonellini, A, Pintor, A, C, and Consolini, Rita

Published
1999

7. Diurnal 18-hydroxy-11-deoxycorticosterone pattern in human stable hypertension.

Author

Sparano F, Sciarra F, Sulon J, Giaquinto G, Mercuri MA, Odoardi A, Tosticroce C, Genard P, and Conti C

Subjects
Adolescent, Adult, Aldosterone blood, Cushing Syndrome complications, Humans, Hydrocortisone blood, Hypertension etiology, Kidney Diseases complications, Male, Nephrosclerosis complications, Renal Artery Obstruction complications, Renin blood, 18-Hydroxydesoxycorticosterone blood, Circadian Rhythm, Desoxycorticosterone analogs & derivatives, Hypertension blood
Abstract

Diurnal 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) pattern was studied with RIA technique in 33 hypertensive patients in supine position and on normal sodium diet. The compound was evaluated every 2 h from 0800-2000 h. Simultaneously, plasma aldosterone and cortisol were measured. Abnormal 18-OH-DOC behavior was observed in only 2 out of 4 patients with Cushing's disease, while sporadic and slight elevations, synchronous with F, were seen in 5 out of 24 stable essential hypertensive patients [1 with normal plasma renin activity (PRA), 1 with low PRA, and 3 with high PRA]. 18-OH-DOC was normal in 2 cases of hypertension due to renal artery stenosis, in 1 patient with nephrosclerosis, and in 1 patient with horseshoe kidney. From these results, 18-OH-DOC does not seem to play an important pathogenetic role in stable essential hypertension, considering also the low mineralocorticoid activity of the compound.

Published
1978
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