Search

A Síndrome de Aspiração de Mecônio (SAM) é uma condição clínica que afeta neonatos expostos ao líquido amniótico contendo mecônio. Essa situação pode resultar em complicações respiratórias sérias, levando à insuficiência respiratória. O uso de oxigênio e/ou Ventilação Mecânica Invasiva (VMI) são tratamentos cruciais para neonatos com problemas respiratórios. O objetivo do estudo é identificar os impactos da VMI em neonatos nascidos a termo com SAM. Trata-se de uma revisão integrativa, realizada em cinco bases de dados eletrônicas: SciELO, ScienceDirect, LILACS, MEDLINE e PubMed. Foram considerados estudos publicados entre 2013 e 2023 em inglês e em português, com métodos de intervenção em neonatos nascidos a termo, de ambos os sexos, de qualquer etnia, que tenham sido submetidos à ventilação mecânica. Quatro estudos foram escolhidos, totalizando 204 participantes com idade gestacional média entre 37,4 e 40,16 semanas. Os profissionais empregaram métodos ventilatórios básicos e avançados no tratamento da disfunção respiratória, juntamente com a utilização de gás Hélio. Foi notada melhora na oxigenação e uma redução no tempo de ventilação mecânica. É evidente a eficácia positiva da VMI na melhoria da oxigenação, especialmente quando combinada com outras estratégias, como o uso de gás Hélio, o que pode resultar em menor tempo de ventilação. Isso destaca a importância das estratégias ventilatórias na proteção pulmonar desses neonatos.

ABSTRACT Objective: To understand the hypoalgesic effect of exercises in obese patients with low back pain. Methods: From the methodological point of view, this is a systematic review study supported by the PRISMA guidelines (2020). Only clinical trials with defined eligibility criteria were included and the methodological evaluation was carried out using the Risk of Bias 2.0 (RoB 2.0) tool. Results: Four clinical trials were found, which underwent an assessment of risk of bias and were mostly categorized as moderate risk of bias or with some concerns. Conclusions: Moderate-intensity interval training (MIIT), high-intensity interval training (HIIT), and total resistance or lumbar spine extension exercises were shown to be effective for pain control, quality of life, and functional performance in obese individuals. On the other hand, the exercises alone did not produce a decrease in body composition. Level of evidence I; Systematic review.

RESUMO Este estudo analisou a intensidade dos jogos Kinect Sports® em universitários através das variáveis hemodinâmicas e da percepção subjetiva de esforço. Tratou-se de um estudo experimental, com 34 jovens estudantes (21.5±1.9anos) que foram submetidos a três sessões consecutivas de jogos, divididas em jogos de boxe, boliche, beisebol e tênis; vôlei de areia, golfe, atletismo e esqui; tênis de mesa, futebol, dardos e futebol americano. A frequência cardíaca (FC), pressão arterial (PA) e percepção subjetiva de esforço (PSE) foram registradas a cada dois minutos de cada jogo. One-way ANOVA for repeated measurements was used to verify differences in HR, BP and PSE at each time of the game and the effect size (p

Abstract Aim: This study aimed to verify the reproducibility of an endurance test for master swimmers. Methods: Seventeen male swimmers, aged from 30 to 50 years (35.06 ± 5.36), weight (78.71 ± 13.06 kg), height (174.35 ± 0.07 cm), participated in this study. The participants underwent the Progressive Swim Test (PSwT), which corresponds to swimming progressively to exhaustion in a 25-meter pool, guided by the recording of sound signals indicating the swimming rhythm. We verified the following variables: heart rate before the test (BHR) and right after the end of the test (AHR), followed by the rate of perceived exertion (RPE) and a total of laps performed (SN - swimming number). For comparison between the three days of tests, the one-way repeated measures ANOVA with Tukey's Post-Hoc was performed. Relative reproducibility was performed by the r test and the intraclass correlation coefficient (ICC). Absolute reproducibility was determined using the coefficient of variation (CV) and the confidence interval (CI). Results: The results showed high reproducibility in (PSwT) in master swimmers in the analyzed variables of intergroup and intragroup with relative reproducibility of r > 0.60 and ICC > 0.70 and absolute reproducibility with CI 95% (lower −1.10 and upper 0.99) and CV < 10%. Most of the cases were within the limits of agreement of the Bland-Altman tests, all variables were considered a level of significance with (p

Introdução: A eletromiografia consiste no estudo, registro e interpretação dos sinais elétricos emitidos pelas fibras musculares ativas durante o processo de contração. Esta técnica abrange aplicações clínicas e em pesquisas científicas. Com o crescimento da população idosa estudos relacionando a produção de força e a técnica da eletromiografia tem sido realizado com o objetivo de quantificar os parâmetros referente a essa capacidade física. Objetivo: Apresentar uma revisão integrativa acerca da relação entre o sinal eletromiográfico e a produção de força em idosos. Métodos: Para a seleção dos artigos utilizou-se das bases de dados PubMed, Scopus, Scielo, Web of Science e Lilacs, por meio do uso dos descritores: “elderly AND electromyography AND muscle strenght“. Resultados e Discussão: Na população idosa, os declínios nos parâmetros fisiológicos e anatômicos tendem a se apresentar com maior frequência, tornando mais crítica a comparação quantitativa devido a diferentes respostas, de individuo para individuo e entre musculaturas diferentes o que pode inviabilizar a linearidade entre produção de força e sinal EMG.. Conclusão: De acordo com a literatura, não há uma relação linear entre a eletromiografia de superfície e a produção de força em idosos. Diferenças em fatores fisiológicos, anatômicos e instrumentais podem explicar esse evento.

This study aimed to verify the association between the genotypic of the receptor gene activated by peroxisome proliferators gamma 2 (PPARy2) and the body composition and the specific indicators of adiposity in practitioners physical exercises, considering nutritional intake, age, and training load as influencing factors. It was conducted a cross-sectional study with 335 adults (47.9 ± 12.7 years, 138 men, body mass index/BMI = 27.0 ± 4.9 kg/m2), practitioners of aerobic exercises in cyclical modalities (running, walking and/or cycling, who spent 328.3 ± 193.6 kcal/day on physical training). The genotyping of the Pro12Ala polymorphism was performed using the PCR-RFLP technique and the body composition measured by bioimpedance (InBody 720). Energy expenditure was based on the compendium of physical activities and caloric intake was measured by 24 h recall questionnaire. The higher prevalence was for the Pro/Pro genotype (76.1% vs. 23.9% of Pro/Ala). Pro/Pro genotypic group showed significant higher mean values for body mass (BM) (p < 0.03 for men and p < 0.02 for women) and BMI (p < 0.00 for men and p < 0.02 for women) and %FAT (p < 0.00), waist-hip ratio (WHR) (p < 0.04), and visceral fat (VF) (p < 0.00) only in men compared to Pro/Ala. Higher frequency of Pro/Pro was observed in the category indicating BMI (p < 0.00 for men and p < 0.03 for women), WRH (p < 0.03 for men and p < 0.00 for women), and %FAT (p < 0.03) (in the latter case, only among men. It was also observed that the frequency of distribution of Pro/Ala in the eutrophic category of the BMI remained independent of all influencers, while WHR and %FAT were independent of the training load, but influenced by nutritional intake and age. In women, the frequency of Pro/Ala distribution at the lowest BMI and WHR values remained independent of all confounding variables. It is concluded that the Pro12Ala polymorphism in the PPARy2 gene consistently influences indicators of body composition and adiposity, regardless of the practitioners of physical training, but the relationship needs to be considered according to age and nutritional intake.

The objective of this study was to verify the influence of the Pro12Ala polymorphism of the PPARγ2 gene in response of a training program on the body composition. Sixty-nine previously inactive men and women (32.8 ± 8.2 years) were genotyped and underwent a 12-week aerobic (running/walking) training program (3–5 sessions, 40 – 60 min per session, and intensity between the aerobic and anaerobic threshold) (experimental group n = 53) or were part of the control group (n = 16). They were tested for aerobic capacity (ergospirometry), body composition (DXA), abdomen, waist and hip circumferences and nutritional assessment before and 48 h after the experimental protocol. Two-way repeated measures ANOVA test was used to verify possible differences in variables between the experimental vs. control groups or Pro/Pro vs. Pro/Ala groups, and the Chi-squared test was used to verify the distribution of responders and non-responders according to genotype (p < 0.05). Frequencies of 75.5% Pro/Pro (n = 40) and 24.5% Pro/Ala (n = 13) were found, without any occurrence of the recessive homozygote. Body fat reduction was initially confirmed compared to a control group which did not exercise (n = 16; 29.1 ± 8.8 years), so that the exercise group obtained a reduction of −1.3 kg vs. −0.3 kg in the control group (p = 0.03). When they were divided by genotype, there were significant changes in fat mass (−1.3 ± 2.1 kg; p = 0.00), lean mass (0.6 ± 1.5 kg; p = 0.02), fat percentage (−1.3 ± 1.6; p = 0.00), waist circumference (−2.2 ± 2.9 cm; p = 0.00), abdomen circumference (−3.3 ± 3.6 cm; p = 0.00) and hip circumference (−2.7 ± 2.7 cm; p = 0.00) for Pro/Pro genotypes; and fat mass (−1.1 ± 1.7 kg; p = 0.04), fat percentage (−0.9 ± 1.5; p = 0.04), abdomen circumference (−3.9 ± 3.5 cm; p = 0.00) and hip circumference (−1.8 ± 1.8 cm; p = 0.00) for Pro/Ala genotypes, without any group interaction differences. The Chi squared test revealed no differences in the distribution of responders or non-responders according to genotype. It is concluded that an aerobic training program promotes weight loss, but the Pro12Ala polymorphism in the PPARγ2 gene does not influence the variability of aerobic-induced exercise weight loss.

Strength training increases systemic oxygen consumption, causing the excessive generation of reactive oxygen species, which in turn, provokes oxidative stress reactions and cellular processes that induce uterine contraction. The aim of this study was to evaluate the possible protective effect of Spirulina platensis (SP), an antioxidant blue algae, on the contractile and relaxation reactivity of rat uterus and the balance of oxidative stress/antioxidant defenses. Female Wistar rats were divided into sedentary (CG), trained (TG), and T + supplemented (TG50, TG100) groups. Reactivity was analyzed by AQCAD, oxidative stress was evaluated by the malondialdehyde (MDA) formation, and the antioxidant capacity was measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Strength training increased contractile reactivity and decreased the pharmaco-mechanical component of relaxing reactivity in rat uterus. In addition, training decreased oxidation inhibition in the plasma and exercise increased oxidative stress in the uterine tissue; however, supplementation with algae prevented this effect and potentiated the increase in antioxidant capacity. Therefore, this study demonstrated that food supplementation prevents changes in reactivity and oxidative stress induced by strength training in a rat uterus, showing for the first time, that the uterus is a target for this exercise modality and antioxidant supplementation with S. platensis is an alternative means of preventing uterine dysfunction.

Asthma is a heterogeneous disease of the airways characterized by chronic inflammation associated with bronchial and smooth muscle hyperresponsiveness. Currently, different murine models for the study of asthma show poor bronchial hyperresponsiveness due to a scarcity of smooth muscle and large airways, resulting in a failure to reproduce smooth muscle hyperreactivity. Thus, we aimed to standardize a guinea pig model of chronic allergic lung inflammation mimicking airway smooth muscle hyperreactivity observed in asthmatics (Asth). Animals were randomly divided into a control group (Ctrl), which received saline (0.9% NaCl), and the Asth group, subjected to in vivo sensitization with ovalbumin (OVA) nebulization. Morphological analysis was performed by hematoxylin-eosin staining. Bronchial hyperresponsiveness was evaluated by nebulization time in the fifth, sixth, and seventh inhalations (NT5-7) and tracheal isometric contractions were assessed by force transducer. Total antioxidant capacity was measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and protein expression by Western blot. Histologically, the Asth group developed peribronchial cellular infiltrate, epithelial hyperplasia and smooth muscle thickening. After the fourth nebulization, the Asth group developed bronchial hyperreactivity. The trachea from the Asth group contracted after in vitro stimulation with OVA, differing from the Ctrl group, which showed no response. Additionally, airway smooth muscle hyperreactivity to carbachol and histamine was observed in the Asth group only in intact epithelium preparations, but not to KCl, and this effect was associated with an augmented production of reactive oxygen species. Moreover, lung inflammation impaired the relaxant potency of isoproterenol only in intact epithelium preparations, without interfering with nifedipine, and it was found to be produced by transforming growth factor-β negative modulation of β adrenergic receptors and, furthermore, big-conductance Ca2+-sensitive K+ channels. These effects were also associated with increased levels of phosphatidylinositol 3-kinases but not extracellular signal-regulated kinases 1/2 or phosphorylation, and augmented α-actin content as well, explaining the increased smooth muscle mass. Furthermore, pulmonary antioxidant capacity was impaired in the Asth group. Therefore, we developed a standardized and easy-to-use, reproducible guinea pig model of lung inflammation that mimics airway smooth muscle hypercontractility, facilitating the investigation of the mechanisms of bronchial hyperresponsiveness in asthma and new therapeutic alternatives.

ABSTRACT AIMS to compare the influence of menopause on body fat, induced by a physical training program. METHODS Twenty-one sedentary women, 10 postmenopausal (MN; 54.6 ± 5.1 years, 42.9 ± 4.1 % body fat) and 11 in the ovulatory state (OS; 35.1 ± 5.4 years, 44.1 ± 5.5 % body fat), performed a training program with aerobic exercise (12 weeks, five times / week, 60 minutes per session). Before and after this program, the following measurements were taken: sum of skin fold (∑D), body fat percentage (%F), waist-hip ratio (WHR) and abdominal circumference (AC). RESULTS MN and OS significantly reduced ΣD (38.5 ± 25.1 mm and 27.7 ± 19.4 mm, respectively), but without differences between the groups. MN group women obtained relative reduction in the suprailiac fold, significantly greater than OS (25 ± 10 vs. 11.5 ± 12 mm), and also a greater reduction in the %F (13.5 ± 8% vs. 6.6 ± 6%). There were very slight reductions in WHR in both groups (0.009 ± 0.02 and 0.005 ± 0.03 in MN and OS, respectively), as well as AC (reduction of 3.5 ± 3 cm and 3.9 ± 2.9 cm for MN and OS), with no differences between groups. CONCLUSION The postmenopausal women responded to a training program with a greater reduction of body fat, but in only one of four evaluated body composition variables.

Introdução: Estudos têm sido desenvolvidos de modo a contribuir para a melhoria da qualidade de vida na terceira idade e um dos aspectos a essa relacionados é a autonomia funcional, que pode ser beneficiada pela prática de atividade física. Objetivo: Comparar a autonomia funcional de idosas fisicamente a tivas e insuficientemente ativas de uma cidade centro sul cearense. Métodos: Estudo observacional, do tipo seccional, para o qual foram convidadas a participar mulheres idosas (>60 anos de idade), aleatoriamente, em diversos locais da cidade de Iguatu-CE. A autonomia funcional foi avaliada por meio do protocolo de autonomia GDLAM. Resultados: Participaram 30 mulheres idosas (60 a 83 anos) foram divididas em dois grupos: G1 (n=15) composto de praticantes de exercícios físicos (66 ± 5,01 anos) e G2 (n=15) de mulheres insuficientemente ativas (67 ± 6,17 anos). A única diferença entre os grupos G1 e G2 foi no teste de vestir e tirar uma camiseta (14,19 ± 4,13s vs 18,24 ± 12,51s). Os valores dos dois grupos ficaram bem próximos. O G1 demostrou um melhor desempenho, com um resultado bom, e o G2 demorou na execução das atividades, com um resultado regular. Conclusão: Mulheres idosas praticantes de exercícios físicos apresentaram maior autonomia funcional significativa no teste de vestir e tirar a camiseta quando comparada a mulheres insuficientemente ativas, demonstrando que a prática de exercício físico pode contribuir para maior autonomia. Functional Autonomy of Elderly Physically Active and Insufficiently Active Elderly Women in a City in the Cearense Middle South: A Cross-Sectional Study Introduction: Studies have been developed in order to contribute to the improvement of quality of life in the third age. One of the aspects related to it is the functional autonomy, which physical activity can benefit. Objective: To compare the functional autonomy of physical active and insufficiently active elderly women in a city center at south of Ceará. Methods: This was a cross-sectional, observational study. In several locations in the city of Iguatu-CE, elderly women (> 60 years of age) were randomly invited to participate. The functional autonomy was evaluated through the GDLAM autonomy protocol. Results: Thirty elderly women (60 to 83 years) were divided into two groups: G1 (n = 15) composed of physical exercise practitioners (66 ± 5.01 years) and G2 (n = 15) of insufficiently active women ( 67 ± 6.17 years). The only difference between groups G1 and G2 was in the in the dressing and undressing a T-shirt test (14.19 ± 4.13s vs 18.24 ± 12.51s). The values of the two groups were very close. The G1 showed a better performance with a good result, and the G2 took a long time to complete the activities, with a regular result. Conclusion: Older women practicing physical exercise presented significant higher functional autonomy in the dressing and undressing a T-shirt test when compared to insufficiently active women, demonstrating that the practice of physical exercise can contribute to greater autonomy.

FUNDAMENTO: A Hipertensão arterial (HA) é uma condição tanto agravante quanto agravada pela Síndrome Metabólica (SM). A menopausa pode tornar o tratamento da hipertensão mais difícil porque é uma condição que favorece a piora nos componentes da SM. Embora existam evidências de que o treinamento com exercícios físicos reduza a pressão arterial, se as condições da menopausa e da SM afetam os benefícios induzidos pelo exercício é algo ainda não evidenciado. OBJETIVO: Comparar os efeitos do treinamento aeróbio na pressão arterial entre mulheres com SM não menopausadas e menopausadas. MÉTODOS: Foram recrutadas 44 mulheres divididas em quatro grupos experimentais: controle não menopausada (CNM: 39,5 ± 1,1 anos, n = 11); controle menopausada (CM: 54,9 ± 1,7 anos, n = 12); aeróbio não menopausada (ANM: 43,1 ± 2,1 anos, n = 11) e aeróbio menopausada (AM: 52,1 ± 1,6 anos, n = 10). Os grupos de exercício realizaram treinamento aeróbio durante três meses, cinco vezes por semana, com intensidade entre 60% e 70% da frequência cardíaca de reserva. A pressão arterial de repouso e a resposta pressórica clínica após 60 minutos de exercício foram medidas antes e após o período treinamento. O teste de ANOVA de dois fatores foi usado, considerando p < 0,05. RESULTADOS: O programa de treinamento resultou em redução da gordura abdominal, glicemia e melhora do VO2 máx. Em comparação aos valores pré-intervenção, Pressão Arterial Sistólica (PAS) e Pressão Arterial Diastólica (PAD) não se alteraram após o treinamento nos grupos CNM, CM, ANM e AM (p > 0,05). CONCLUSÃO: Três meses de treinamento aeróbio melhora componentes da SM, mas não altera a pressão arterial de repouso, nem a resposta pressórica aguda após uma sessão de exercício aeróbio em mulheres com SM.