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3 results on '"Gregory, Fink"'

1. Primer on the Autonomic Nervous System

Author

Italo Biaggioni, Kirsteen Browning, Gregory Fink, Jens Jordan, Phillip A. Low, Julian F.R. Paton, Italo Biaggioni, Kirsteen Browning, Gregory Fink, Jens Jordan, Phillip A. Low, and Julian F.R. Paton

Subjects
Autonomic nervous system--Physiology, Autonomic nervous system--Diseases, Autonomic nervous system--Pathophysiology
Abstract

Primer on the Autonomic Nervous System, Fourth Edition provides a concise and accessible overview of autonomic neuroscience for students, scientists, and clinicians. The book's 142 chapters draw on the expertise of more than 215 basic scientists and clinicians who discuss key information on how the autonomic nervous system controls the body, particularly in response to stress. This new edition also focuses on the translational crossover between basic and clinical research. In addition to comprehensively covering all aspects of autonomic physiology and pathology, topics such as psychopharmacology decoding and modulating nerve function are also explored. - Provides concise and practical information on the autonomic nervous system - Discusses all aspects of autonomic physiology and pathology - Contains new content on psychopharmacology and modulating nerve function

Published
2023

2. Maternal Catecholamine Levels in Midpregnancy and Risk of Preterm Delivery

Author

Mohammad H. Rahbar, Gregory Fink, Yan Tian, Bertha L. Bullen, Adroaldo J. Zanella, Patricia K. Senagore, Claudia Holzman, Anjali Sapkal, Eric DeVos, and Cheryl Leece

Subjects
medicine.medical_specialty, Fetal Membranes, Premature Rupture, Epidemiology, Original Contributions, Bedtime, Young Adult, Catecholamines, Pregnancy, Risk Factors, Internal medicine, Medicine, Humans, Risk factor, business.industry, Obstetrics, Pregnancy Outcome, Gestational age, Odds ratio, Middle Aged, medicine.disease, Endocrinology, Premature birth, Creatinine, Pregnancy Trimester, Second, Catecholamine, Premature Birth, Female, business, Premature rupture of membranes, medicine.drug
Abstract

Associations between stress hormones and preterm delivery have not been fully explored. In this study, pregnant women enrolled from 52 clinics in 5 Michigan communities (1998–2004) provided urine samples for 3 days (waking and bedtime) during midpregnancy. Urinary catecholamine levels (epinephrine, norepinephrine, and dopamine) were measured in a subcohort (247 preterm and 760 term deliveries), and a 3-day median value was calculated. Polytomous logistic regression models assessed relations between catecholamine quartiles (of the median) and a 4-level outcome variable (i.e., term (referent) and 3 preterm delivery subtypes: spontaneous; premature rupture of membranes; and medically indicated). Final models incorporated other relevant covariates (e.g., creatinine, demographic, behavior). The risk of spontaneous preterm delivery was increased in the highest versus lowest quartile of norepinephrine and dopamine: norepinephrine, waking (adjusted odds ratio (AOR) ¼ 3.7, 95% confidence interval (CI): 1.8, 7.9) and bedtime (AOR ¼ 2.5, 95% CI: 1.3, 4.9); dopamine, waking (AOR ¼ 2.6, 95% CI: 1.4, 5.1) and bedtime (AOR ¼ 2.3, 95% CI: 1.2, 4.6). Adjusted odds ratios were further strengthened after removing women whose placentas showed evidence of acute infection or vascular pathology. High catecholamine levels in maternal urine may be indicative of excess stressors and/or predisposition to elevated sympathetic activation that contributes to increased risk of spontaneous preterm delivery. catecholamines; dopamine; epinephrine; gestational age; norepinephrine; pregnancy; pregnancy outcome; premature birth

Published
2009

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