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2 results on '"Hilkka Kontro"'

1. Carbohydrate and Protein Co-Ingestion Postexercise Does Not Improve Next-Day Performance in Trained Cyclists.

Author

Hilkka Kontro, Kozior, Marta, Whelehan, Gráinne, Amigo-Benavent, Miryam, Norton, Catherine, Carson, Brian P., and Jakeman, Phil

Subjects
*PROTEINS, *ENDURANCE sports training, *INGESTION, *COOLDOWN, *CYCLING, *INSULIN, *RANDOMIZED controlled trials, *CARBOHYDRATES, *BLIND experiment, *DESCRIPTIVE statistics, *ATHLETIC ability, *CROSSOVER trials, *GLYCOGEN, *STATISTICAL sampling
Abstract

Supplementing postexercise carbohydrate (CHO) intake with protein has been suggested to enhance recovery from endurance exercise. The aim of this study was to investigate whether adding protein to the recovery drink can improve 24-hr recovery when CHO intake is suboptimal. In a double-blind crossover design, 12 trained men performed three 2-day trials consisting of constant-load exercise to reduce glycogen on Day 1, followed by ingestion of a CHO drink (1.2 g⋅kg-1⋅2 hr-1) either without or with added whey protein concentrate (CHO + PRO) or whey protein hydrolysate (CHO + PROH) (0.3 g⋅kg-1⋅2 hr-1). Arterialized blood glucose and insulin responses were analyzed for 2 hr postingestion. Time-trial performance was measured the next day after another bout of glycogen-reducing exercise. The 30-min time-trial performance did not differ between the three trials (M ± SD, 401 ±75, 411 ±80, 404 ±58 kJ in CHO, CHO + PRO, and CHO + PROH, respectively, p = .83). No significant differences were found in glucose disposal (area under the curve [AUC]) between the postexercise conditions (364 ± 107, 341 ± 76, and 330 ± 147, mmol⋅L-1⋅2 hr-1, respectively). Insulin AUC was lower in CHO (18.1 ± 7.7 nmol⋅L-1⋅2 hr-1) compared with CHO + PRO and CHO + PROH (24.6 ± 12.4 vs. 24.5 ± 10.6, p = .036 and .015). No difference in insulin AUC was found between CHO + PRO and CHO + PROH. Despite a higher acute insulin response, adding protein to a CHO- based recovery drink after a prolonged, high-intensity exercise bout did not change next-day exercise capacity when overall 24-hr macronutrient and caloric intake was controlled. [ABSTRACT FROM AUTHOR]

Published
2021
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2. Effect of 24-Week, Late-Evening Ingestion of a Calcium-Fortified, Milk-Based Protein Matrix on Biomarkers of Bone Metabolism and Site-Specific Bone Mineral Density in Postmenopausal Women with Osteopenia

Author

Catherine Norton, Manjula Hettiarachchi, Rachel Cooke, Marta Kozior, Hilkka Kontro, Rosemary Daniel, and Philip Jakeman

Subjects
milk protein matrix, nutrient timing, postmenopausal women, nutrient intervention, Collagen Type I, Eating, Bone Density, Animals, Humans, bone health, Osteoporosis, Postmenopausal, 4207 Sports science and exercise, Nutrition and Dietetics, randomized control trial, bone remodelling, bone turnover markers, osteopenia, Milk Proteins, Calcium, Dietary, Postmenopause, Bone Diseases, Metabolic, Milk, Calcium, Female, Bone Remodeling, Sports science and exercise, Biomarkers, Food Science
Abstract

Dietary calcium intake is a modifiable, lifestyle factor that can affect bone health and the risk of fracture. The diurnal rhythm of bone remodelling suggests nocturnal dietary intervention to be most effective. This study investigated the effect of daily, bed-time ingestion of a calcium-fortified, milk-derived protein matrix (MBPM) or control (CON), for 24 weeks, on serum biomarkers of bone resorption (C-terminal telopeptide of type I collagen, CTX) and formation (serum pro-collagen type 1 N-terminal propeptide, P1NP), and site-specific aerial bone mineral density (BMD), trabecular bone score (TBS), in postmenopausal women with osteopenia. The MBPM supplement increased mean daily energy, protein, and calcium intake, by 11, 30, and 107%, respectively. 24-week supplementation with MBPM decreased CTX by 23%, from 0.547 (0.107) to 0.416 (0.087) ng/mL (p < 0.001) and P1NP by 17%, from 60.6 (9.1) to 49.7 (7.2) μg/L (p < 0.001). Compared to CON, MBPM induced a significantly greater reduction in serum CTX (mean (CI95%); −9 (8.6) vs. −23 (8.5)%, p = 0.025 but not P1NP −19 (8.8) vs. −17 (5.2)%, p = 0.802). No significant change in TBS, AP spine or dual femur aerial BMD was observed for CON or MBPM. This study demonstrates the potential benefit of bed-time ingestion of a calcium-fortified, milk-based protein matrix on homeostatic bone remodelling but no resultant treatment effect on site-specific BMD in postmenopausal women with osteopenia.

Published
2022
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