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The Sakyamuni Pagoda of Fogong Temple, also known as the Yingxian Wooden Pagoda or the Wooden Pagoda of Ying County, is China's oldest and tallest wooden pagoda. This pagoda was constructed in 1056 and has faced many challenges, including earthquakes, wars, and mistreatment. However, it is currently in danger of potential collapse due to severe structural challenges. Preserving this historic monument requires interdisciplinary collaboration across architectural history, materials science, and engineering. This paper proposes the development of a parametric model to build the pagoda that can be used for future preservation efforts. While not precisely reflecting the pagoda's current condition, with the changes in inputs, the geometries of the structural members can be updated in real time, which offers adaptability crucial for preservation efforts. With the understanding of the original construction techniques, including its leaning column systems, the model not only helps preservation but also reveals the creativity of the architects or the craftsmen at the time. The 3D model, which includes more than 32,000 pieces along with the parametric files that can generate the column grid and dougongs, has been published along with this paper, and those files are available in the Data Availability Statement. In summary, the full digital model presented alongside this paper, unavailable elsewhere to the general public, serves as a practical preservation tool that can also be used for raising awareness for this cultural heritage site. [ABSTRACT FROM AUTHOR]

In recent years, the safety of cables of cable‐stayed bridges has attracted extensive attention, and the rise of radar technology has provided new possibilities for the performance testing of cable‐stayed bridges. In this regard, this paper introduces the principle of microwave radar measurement technology and uses the microwave cable force measuring instrument to perform noncontact microwave radar cable force measurement on a total of 72 stay cables in Shifeng Bridge and San‐Jiadian Bridge compared with the measurement results of the cloud smart collector. The results show that the fundamental frequency deviation rate of 71 cables is within 3%, and the cable force deviation rate of 67 cables is within 5%. This shows that the microwave radar cable force measurement method has a high degree of reliability and accuracy; meanwhile, it is also found that the forces on the left and right sides of the two bridges are in a symmetrical state, and the structure is in good condition; the signal characteristics are obvious, and the simultaneous measurement of multiple cables can be realized, and it is not limited by weather, site, and the length of the stay cable and has strong practical value. [ABSTRACT FROM AUTHOR]

The gravity-driven settlement process of bi-disperse particle clouds is investigated by using a computational fluid dynamic–discrete element method coupled model. The purpose of this work is to discuss the effect of particle size ratio and cloud size on cloud settling, with an emphasis on cloud morphological changes and dynamic mechanisms, as well as the spatial distribution and movement rules of each dispersed phase. The simulation results demonstrate that the settling of bi-dispersed clouds is accompanied by cloud breakup and the separation of large and small particles. The rise in particle size ratio will make cloud breakup more difficult, and the increase in cloud size facilitates the separation of large and small particles in the cloud. Essentially, cloud breakup and separation are closely related to weak inter-particle forces, and the thresholds for these two events are, respectively, proposed. Decomposable clouds will continuously flatten into toruses before breaking up, with an increasing aspect ratio γ that suggests a weakening of the interactions. When the aspect ratio exceeds a critical value of 2, the cloud breaks up. The non-dimensional distance l d * between large and small particles, describing the interaction between two dispersed phases, correlates with their separation. The critical distance for separation is 29. Furthermore, the sequence in which the two critical conditions are met determines the order in which cloud breakup and particle separation take place. [ABSTRACT FROM AUTHOR]

Background: Pulsed field ablation (PFA) has emerged as a novel non‐thermal modality with highly myocardium‐specific. However, the PFA catheter based on contact force (CF)‐sensing has not been reported. The study aimed to evaluate the efficacy and safety of a novel CF‐sensing PFA catheter. Methods: First, different CF (5, 15, 25, and 35 g) of the novel PFA catheter were evaluated on lesion dimensions during ablation on right and left ventricle in two pigs. Next, this catheter was further evaluated on four typical sites of superior vena cava (SVC), cavotricuspid isthmus (CTI), right superior pulmonary vein (RSPV), and right inferior pulmonary vein (RIPV) for atrial ablation in another six pigs. Electrical isolation was evaluated immediately after ablation and 30‐day survival. Chronic lesions were assessed via histopathology after euthanasia. Acute and chronic safety outcomes were observed peri‐ and post‐procedurally. Results: In ventricular ablation, increased CF from 5 to 15 g produced significantly greater lesion depth but nonsignificant increases from 15 to 35 g. In atrial ablation, the novel CF‐sensing PFA deliveries produced an acute attenuation of local electrograms and formation of a continuous line of block in all 6 pigs. The ablation line remained sustained blockage at the 30‐day survival period. The CF of SVC, CTI, RSPV, and RIPV was 9.4 ± 1.5, 14.5 ± 3.2, 17.2 ± 2.6, and 13.4 ± 2.8 g, respectively. Moreover, no evidence of damage to esophagus or phrenic nerve was observed. Conclusion: The novel CF‐sensing PFA catheter potentiated efficient, safe, and durable ablation, without causing damage to the esophagus or phrenic nerve. [ABSTRACT FROM AUTHOR]

Three-dimensional models of trees that correspond to the real-world forms of the trees on the ground are used in urban planning, solar power estimation, and other disciplines. Previous studies have focused on generating 3D tree models from high-density point cloud data such as Terrestrial Laser Scanning (TLS) data, which is expensive and limited to small spatial extents. However, there has been limited exploration of inexpensive solutions to model trees over large spatial extents. The goal of this study is to use widely available discrete return Airborne Laser Scanning (ALS) data along with field-captured tree photographs and Google Street View (GSV) images to develop 3D equivalents of trees over larger spatial extents. To this end, we designed a process to assign representative 3D models for individual trees in discrete return ALS point clouds. This study demonstrates the use of a Convolutional Neural Network (CNN) model and 3D models generated with Structure from Motion (SfM) for the realistic modelling of deciduous non-overlapping trees from discrete return ALS data. We classified and labelled the crown shapes of deciduous trees in a study area into four classes based on GSV images of trees. We delineated and segmented non-overlapping deciduous trees from ALS data and reduced them to 2D images using voxel point counts. Next, we trained a CNN architecture to match the 2D images to the corresponding classes observed from GSV images. For each class, we created a representative 3D tree model using field-captured circumnavigational photos of trees and SfM. To demonstrate 3D visualization using the 3D tree models, we created a 3D visualization of the trees surrounding a parking lot. The trained CNN model from this study can be used to classify non-overlapping deciduous trees from discrete return ALS data and subsequently visualize near-realistic 3D tree models of trees. [ABSTRACT FROM AUTHOR]

How tissue regeneration programs are triggered by injury has received limited research attention. Here we investigate the existence of enhancer regulatory elements that are activated in regenerating tissue. Transcriptomic analyses reveal that leptin b (lepb) is highly induced in regenerating hearts and fins of zebrafish. Epigenetic profiling identified a short DNA sequence element upstream and distal to lepb that acquires open chromatin marks during regeneration and enables injury-dependent expression from minimal promoters. This element could activate expression in injured neonatal mouse tissues and was divisible into tissue-specific modules sufficient for expression in regenerating zebrafish fins or hearts. Simple enhancer-effector transgenes employing lepb-linked sequences upstream of pro- or anti-regenerative factors controlled the efficacy of regeneration in zebrafish. Our findings provide evidence for 'tissue regeneration enhancer elements' (TREEs) that trigger gene expression in injury sites and can be engineered to modulate the regenerative potential of vertebrate organs., The capacity for complex tissue regeneration is unevenly distributed among vertebrate tissues and species. Salamanders and zebrafish possess remarkable potential to regenerate tissues like amputated appendages, resected heart muscle, and [...]