9 results on '"Hu, Yuebing"'
Search Results
2. Effects of aging time on the crystallization/transformation of hydrothermal synthesis alkali-activated fly ash-based zeolite.
- Author
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Cao, Fangcheng, Ouyang, Yiping, Huang, Zekun, Gong, Yuting, Hu, Yuebing, and He, Zhen
- Subjects
ZEOLITES ,HYDROTHERMAL synthesis ,FERRIC oxide ,MESOPOROUS materials - Published
- 2022
- Full Text
- View/download PDF
3. Is Peri-Operative Steroid Replacement Therapy Necessary for the Pituitary Adenomas Treated with Surgery? A Systematic Review and Meta Analysis.
- Author
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Tohti, Mamatemin, Li, Junyang, Zhou, Yuan, Hu, Yuebing, Yu, Zhuang, and Ma, Chiyuan
- Subjects
PITUITARY diseases ,PERIOPERATIVE care ,STEROID drugs ,OSTEOPENIA ,SYSTEMATIC reviews ,THERAPEUTICS - Abstract
Background: Patients with pituitary adenomas usually receive “stress dose” steroids in the peri-operative peroids. Though randomized controlled trials(RCT) have not been performed to assess the necessity of steroid coverage, there are several studies that explained the changes of adrenal function during peri-operative peroids. The aim of the present study is to investigate whether it is necessary to employ conventional peri-operative glucocorticoid replacement therapy to all the patients undergoing surgery. Methods: We searched studies addressing peri-operative steroids coverage for pituitary adenomas in the Web of Science, Medline and the Cochrane Library. Then we extracted studies about peri-operative morning serum cortisol(MSC) levels, morbidity of early postoperative adrenal insufficiency, postoperative diabetes insipidus, relationships between MSC levels and adrenal integrity. We used RevMan Software to combine the results for meta-analysis. We used fixed-effects models for there was no significant heterogeneity existed. Findings: There are 18 studies from 11 countries published between 1987 and 2013 including 1224 patients. The postoperative serum cortisol levels were significantly increased compared with the preoperative one in hypothalamic-pituitary-adrenal axis(HPAA) functions preserved patients(P<0.00001). The morbidity of early postoperative adrenal insufficiency ranged from 0.96% to 12.90%, with the overall morbidity of 5.55%(41/739). There was no significant differences of early postoperative diabetes insipidus between no supplementation patients and in supplementation patients(P=0.82). Conversely, there may be some disadvantages of high levels of cortisols such as high incidence of osteopenia and bone derangement and even the increased mortality rate. The patients with MSC levels of less than 60 nmol/l at 3 days after operation is considered as adrenal insufficient and more than 270 nmol/l as adrenal sufficient. To patients with MSC levels of 60–270 nmol/l, we need more clinical data to establish further cortisol supplementation criteria. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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4. Consensus control of multi-agent systems with missing data in actuators and Markovian communication failure.
- Author
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Hu, Yuebing, Lam, James, and Liang, Jinling
- Subjects
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MULTIAGENT systems , *CONTROL theory (Engineering) , *MISSING data (Statistics) , *ACTUATORS , *MARKOV processes , *COMPUTER networks , *FAILURE Analysis System (Computer system) - Abstract
This article investigates the consensus problem of multi-agent systems (MASs) with imperfect communication both in channels and in actuators. The data transmission among agents may fail due to limited communication capacity, and the actuators may fail to receive information owing to noisy environment. We use a Markov chain approach to characterise the occurrence of the two types missing data in a unified framework. A sufficient consensus condition is first obtained in terms of linear matrix inequalities. Then, based on this condition, a novel controller design method is further developed such that the MAS with imperfect communication reaches mean-square consensus. It is shown that the consensus problem for MASs with switching topology can be regarded as a special case of the problem considered in this article, and the related theoretical results are presented as well. Numerical examples are provided to illustrate the effectiveness of the proposed approach. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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5. Adaptive consensus with a virtual leader of multiple agents governed by locally Lipschitz nonlinearity.
- Author
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Hu, Yuebing, Su, Housheng, and Lam, James
- Abstract
SUMMARY This paper is concerned with the second-order consensus problem of multi-agent systems with a virtual leader, where all agents and the virtual leader share the same intrinsic dynamics with a locally Lipschitz condition. It is assumed that only a small fraction of agents in the group are informed about the position and velocity of the virtual leader. A connectivity-preserving adaptive controller is proposed to ensure the consensus of multi-agent systems, wherein no information about the nonlinear dynamics is needed. Moreover, it is proved that the consensus can be reached globally with the proposed control strategy if the degree of the nonlinear dynamics is smaller than some analytical value. Numerical simulations are further provided to illustrate the theoretical results. Copyright © 2012 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
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6. Analysis on the Technical Indexes of the Best Men's Teams in the Latest Three CUBA League Matches.
- Author
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HU Yuebing
- Abstract
The article discusses a study which analyzes the technical indexes of top four basketball teams in the CUBA League matches in China. Results of the study show that there is an increase in field goal percentage, intercepting and some basic skills such as passing and catching. The teams were weak in basic skills and lack normalization in techniques.
- Published
- 2008
7. Identification of potential biomarkers to differentially diagnose solid pseudopapillary tumors and pancreatic malignancies via a gene regulatory network.
- Author
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Li, Pengping, Hu, Yuebing, Yi, Jiao, Li, Jie, Yang, Jie, and Wang, Jin
- Subjects
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DIFFERENTIAL diagnosis , *MOLECULAR structure , *PANCREATIC tumors , *DIAGNOSIS - Abstract
Background: Solid pseudopapillary neoplasms (SPN) are pancreatic tumors with low malignant potential and good prognosis. However, differential diagnosis between SPN and pancreatic malignancies including pancreatic neuroendocrine tumor (PanNET) and ductal adenocarcinoma (PDAC) is difficult. This study tried to identify candidate biomarkers for the distinction between SPN and the two malignant pancreatic tumors by examining the gene regulatory network of SPN.Methods: The gene regulatory network for SPN was constructed by a co-expression model. Genes that have been reported to be correlated with SPN were used as the clues to hunt more SPN-related genes in the network according to a shortest path approach. By means of the K-nearest neighbor algorithm (KNN) classifier evaluated by the jackknife test, sets of genes to distinguish SPN and malignant pancreatic tumors were determined.Results: We took a new strategy to identify candidate biomarkers for differentiating SPN from the two malignant pancreatic tumors PanNET and PDAC by analyzing shortest paths among SPN-related genes in the gene regulatory network. 43 new SPN-relevant genes were discovered, among which, we found hsa-miR-194 and hsa-miR-7 along with 7 transcription factors (TFs) such as SOX11, SMAD3 and SOX4 etc. could correctly differentiate SPN from PanNET, while hsa-miR-204 and 4 TFs such as SOX9, TCF7 and PPARD etc. were demonstrated as the potential markers for SPN versus PDAC. 14 genes were demonstrated to serve as the candidate biomarkers for distinguishing SPN from PanNET and PDAC when considering them as malignant pancreatic tumors together.Conclusion: This study provides new candidate genes related to SPN and the potential biomarkers to differentiate SPN from PanNET and PDAC, which may help to diagnose patients with SPN in clinical setting. Furthermore, candidate biomarkers such as SOX11 and hsa-miR-204 which could cause cell proliferation but inhibit invasion or metastasis may be of importance in understanding the molecular mechanism of pancreatic oncogenesis and could be possible therapeutic targets for malignant pancreatic tumors. [ABSTRACT FROM AUTHOR]- Published
- 2015
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8. Expression of AGR2 in pituitary adenomas and its association with tumor aggressiveness.
- Author
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Tohti M, Li J, Ma C, Li W, Lu Z, and Hu Y
- Abstract
The aim of the present study was to study the expression of anterior gradient 2 (AGR2) to determine its clinical significance in pituitary adenoma (PA), and to evaluate the potential effect of AGR2 on the diagnosis, therapy or prognosis of PA. Immunohistochemistry was performed to detect the expression of AGR2 in 117 PA tissue samples. Western blotting was performed to confirm the expression profile of AGR2 in different subtypes of PAs. The data showed that in 117 different histological subtypes of PA, 51.3% exhibited AGR2-positive expression. Although AGR2 expression occurred more frequently in PAs secreting growth hormone (GH; 62.5%), adrenocorticotropic hormone (ACTH; 80.0%) and follicle-stimulating hormone (FSH; 75.0%),the positive expression rate of AGR2 showed no statistically significant differences between PA subtypes (P>0.05). The association between AGR2 expression and clinical parameters was analyzed using a χ
2 test, or Fisher's exact probability test when appropriate. The result showed that the aggressiveness of PA was significantly associated with AGR2 expression, and that in the majority of aggressive PAs, AGR2 was negative (P<0.001). In conclusion, the current study detected the expression of AGR2 in different subtypes of PAs for the first time. The data indicated that GH-, ACTH- and FSH-secreting PAs present marginally more frequently with AGR2 expression, howeverm the association was not significant (P>0.05). AGR2 may be a target for the study of PA aggressiveness, and a potential index for the diagnosis or prognosis of PAs.- Published
- 2015
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9. The expression profile of Dopamine D2 receptor, MGMT and VEGF in different histological subtypes of pituitary adenomas: a study of 197 cases and indications for the medical therapy.
- Author
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Wang Y, Li J, Tohti M, Hu Y, Wang S, Li W, Lu Z, and Ma C
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- Adenoma genetics, Antibodies, Monoclonal, Humanized administration & dosage, Bevacizumab, Blotting, Western, DNA Modification Methylases genetics, DNA Repair Enzymes genetics, Dacarbazine administration & dosage, Dacarbazine analogs & derivatives, Female, Humans, Immunohistochemistry, Male, Pituitary Neoplasms genetics, Receptors, Dopamine D2 genetics, Temozolomide, Tumor Suppressor Proteins genetics, Vascular Endothelial Growth Factor A genetics, Adenoma metabolism, Adenoma therapy, DNA Modification Methylases biosynthesis, DNA Repair Enzymes biosynthesis, Pituitary Neoplasms drug therapy, Pituitary Neoplasms metabolism, Receptors, Dopamine D2 biosynthesis, Tumor Suppressor Proteins biosynthesis, Vascular Endothelial Growth Factor A biosynthesis
- Abstract
Background: To study the expression of D2R, MGMT and VEGF for clinical significance in pituitary adenomas, and to predict the potential curative medical therapy of dopamine agonists, temozolomide and bevacizumab on pituitary adenomas., Methods: Immunohistochemistry and western blot were performed to detect the expression of expression of D2R, MGMT and VEGF in pituitary adenoma tissue samples. The ratio of high expression of D2R, MGMT or VEGF in different subtypes of PA was compared by the use of chi-squared tests. The relationships between D2R, MGMT and VEGF expression were assessed by the Spearman rank correlation test. The association between their expression and clinical parameters was analyzed using a chi-squared test, or Fisher's exact probability test when appropriate., Results: The data showed that in 197 different histological subtypes of pituitary adenomas (PAs), 64.9% of them were D2R high expression, 86.3% were MGMT low expression and 58.9% were VEGF high expression. D2R high expression existed more frequently in PRL- and GH- secreting PAs. MGMT low expression existed in all PA subtypes. VEGF high expression existed more frequently in PRL, ACTH, FSH secreting and non-functioning PAs. The data of western blot also support the results. Spearman's rank correlation analysis showed that expression of MGMT was positively associated with D2R (r = 0.154, P = 0.031) and VEGF (r = 0.161, P = 0.024) in PAs, but no correlation was showed between D2R and VEGF expression (r = -0.025, P = 0.725 > 0.05). The association between their expression and clinical parameters was analyzed using a chi-squared test, or Fisher's exact probability test when appropriate, but the result showed no significant association., Conclusions: PRL-and GH-secreting PAs exist high expression of D2R, responding to dopamine agonists; Most PAs exist low expression of MGMT and high expression of VEGF, TMZ or bevacizumab treatment could be applied under the premise of indications.
- Published
- 2014
- Full Text
- View/download PDF
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