12 results on '"Huijsmans, Rosalie J."'
Search Results
2. Design of the ExCersion-VCI study: The effect of aerobic exercise on cerebral perfusion in patients with vascular cognitive impairment
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Leeuwis, Anna E., Hooghiemstra, Astrid M., Amier, Raquel, Ferro, Doeschka A., Franken, Leonie, Nijveldt, Robin, Kuijer, Joost P.A., Bronzwaer, Anne-Sophie G.T., van Lieshout, Johannes J., Rietberg, Marc B., Veerbeek, Janne M., Huijsmans, Rosalie J., Backx, Frank J.G., Teunissen, Charlotte E., Bron, Esther E., Barkhof, Frederik, Prins, Niels D., Shahzad, Rahil, Niessen, Wiro J., de Roos, Albert, van Osch, Matthias J.P., van Rossum, Albert C., Biessels, Geert J., and van der Flier, Wiesje M.
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- 2017
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3. The efficacy of a blended intervention to improve physical activity and protein intake for optimal physical recovery after oncological gastrointestinal and lung cancer surgery, the Optimal Physical Recovery After Hospitalization (OPRAH) trial: study protocol for a randomized controlled multicenter trial
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de Leeuwerk, Marijke, de Groot, Vincent, Dam, Suzanne ten, Kruizenga, Hinke, Weijs, Peter, Geleijn, Edwin, van der Leeden, Marike, van der Schaaf, Marike, Dickhoff, Chris, Besselink, Marc G., Tuynman, Jurriaan B., van Berge Henegouwen, Mark I., Erdmann, Joris I., Huijsmans, Rosalie J., van der Ploeg, Hidde P., Eskes, Anne M., Pijnappels, Mirjam A. G. M., van Leeuwen, Liesbeth Schuijs, Smits, Anke B., and van Dijk, Jasmijn
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LUNG surgery ,GASTROINTESTINAL cancer ,ONCOLOGIC surgery ,RANDOMIZED controlled trials ,LUNG cancer ,PHYSICAL activity ,COACHING psychology ,MUSCLE mass - Abstract
Background: Improving physical activity, especially in combination with optimizing protein intake, after surgery has a potential positive effect on recovery of physical functioning in patients after gastrointestinal and lung cancer surgery. The aim of this randomized controlled trial is to evaluate the efficacy of a blended intervention to improve physical activity and protein intake after hospital discharge on recovery of physical functioning in these patients. Methods: In this multicenter single-blinded randomized controlled trial, 161 adult patients scheduled for elective gastrointestinal or lung cancer surgery will be randomly assigned to the intervention or control group. The purpose of the Optimal Physical Recovery After Hospitalization (OPRAH) intervention is to encourage self-management of patients in their functional recovery, by using a smartphone application and corresponding accelerometer in combination with coaching by a physiotherapist and dietician during three months after hospital discharge. Study outcomes will be measured prior to surgery (baseline) and one, four, eight, and twelve weeks and six months after hospital discharge. The primary outcome is recovery in physical functioning six months after surgery, and the most important secondary outcome is physical activity. Other outcomes include lean body mass, muscle mass, protein intake, symptoms, physical performance, self-reported limitations in activities and participation, self-efficacy, hospital readmissions and adverse events. Discussion: The results of this study will demonstrate whether a blended intervention to support patients increasing their level of physical activity and protein intake after hospital discharge improves recovery in physical functioning in patients after gastrointestinal and lung cancer surgery. Trial registration: The trial has been registered at the International Clinical Trials Registry Platform at 14–10-2021 with registration number NL9793. Trial registration data are presented in Table 1. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Translating Evidence from Dutch Exercise Oncology Trials in Patients with Breast Cancer into Clinical Practice Using the RE-AIM Framework.
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Ten Tusscher, Marieke R., Stuiver, Martijn M., Kampshoff, Caroline S., Huijsmans, Rosalie J., Aaronson, Neil K., Velthuis, Miranda, Gal, Roxanne, Van Waart, Hanna, May, Anne M., and Buffart, Laurien M.
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BREAST tumor treatment ,AEROBIC capacity ,EFFECT sizes (Statistics) ,PATIENT satisfaction ,CONCEPTUAL structures ,TREATMENT effectiveness ,HEALTH insurance reimbursement ,CANCER fatigue ,QUALITY of life ,COST effectiveness ,DESCRIPTIVE statistics ,MEDICAL practice ,PATIENT compliance ,EXERCISE therapy ,DOSE-response relationship in biochemistry - Abstract
Purpose. We aimed to evaluate the potential for implementing exercise interventions for patients with breast cancer in the Netherlands, based on findings of the Dutch randomized controlled trials in this population. Methods. We evaluated the implementation of four Dutch exercise trials retrospectively, using the five dimensions of the RE-AIM framework: Reach (exercise participation rate), Effectiveness for physical fitness, fatigue, quality of life, and physical function, Adoption (e.g., satisfaction of physical therapists guiding the exercise intervention), Implementation (cost-effectiveness and exercise adherence correlates thereof), and Maintenance (maintenance of exercise levels by individual patients and sustainability of exercise delivery at organization level). Thereby, we reflect on these results using (international) literature to gain better insight in overall barriers, facilitators, and opportunities for further implementation of exercise interventions. Results. Participation rates of 44–52% not only indicated acceptable Reach in the context of a trial but also indicated room for improvement. Effectiveness of exercise during and after treatment was demonstrated in most trials showing benefits for aerobic fitness, physical fatigue, quality of life and physical function, and high patient satisfaction. Adoption of the exercise interventions by physical therapists was adequate (satisfaction score: 7.5 out of 10). Evaluation of Implementation indicated adequate adherence to supervised exercise, inconsistent findings on potential correlates of adherence, and promising results on cost-effectiveness. Currently, reimbursement for exercise programs is lacking. Maintenance of intervention effects at the patient level was limited and inconsistent. Maintenance of intervention availability at the organizational level was facilitated by an extensive network of specially trained physical therapists, but better communication and collaboration between different healthcare professionals are desired. Conclusions. Improved implementation could particularly be achieved by increasing reach and improved focus on exercise maintenance on both the patient and organizational level. [ABSTRACT FROM AUTHOR]
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- 2023
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5. The effectiveness of physical activity interventions using activity trackers during or after inpatient care: a systematic review and meta-analysis of randomized controlled trials.
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de Leeuwerk, Marijke E., Bor, Petra, van der Ploeg, Hidde P., de Groot, Vincent, van der Schaaf, Marike, van der Leeden, Marike, on behalf of the OPRAH consortium, Geleijn, Edwin, van Vliet, Vincent, Geelen, Sven J. G., Huijsmans, Rosalie J., Kruizenga, Hinke M., Weijs, Peter J. M., ten Dam, Suzanne, Besselink, Marc G., Dickhoff, Chris, Tuynman, Jurriaan B., van Berge Henegouwen, Mark I., Eskes, Anne M., and Pijnappels, Mirjam A. G. M.
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PHYSICAL fitness mobile apps ,EVALUATION of medical care ,ONLINE information services ,CINAHL database ,MEDICAL information storage & retrieval systems ,META-analysis ,FUNCTIONAL status ,MATHEMATICAL models ,SYSTEMATIC reviews ,WEARABLE technology ,SPORTS ,PHYSICAL activity ,HOSPITAL care ,BODY movement ,DESCRIPTIVE statistics ,THEORY ,PATIENT care ,MEDLINE ,INFORMATION storage & retrieval systems ,REHABILITATION ,HEALTH promotion ,EVALUATION - Abstract
Background: Promoting physical activity (PA) in patients during and/or after an inpatient stay appears important but challenging. Interventions using activity trackers seem promising to increase PA and enhance recovery of physical functioning. Objective: To review the effectiveness of physical activity interventions using activity trackers on improving PA and physical functioning, compared to usual care in patients during and/or after inpatient care. In addition, it was determined whether the following intervention characteristics increase the effectiveness of these interventions: the number of behaviour change techniques (BCTs) used, the use of a theoretical model or the addition of coaching by a health professional. Design: Systematic review and meta-analysis. Data Sources: PubMed, EMBASE, Cinahl, SportDiscus and Web of Science databases were searched in March 2020 and updated in March 2021. Eligibility criteria for selecting studies: Randomized controlled trials (RCTs) including interventions using activity trackers and feedback on PA in adult patients during, or less than 3 months after, hospitalization or inpatient rehabilitation. Methods: Following database search and title and abstract screening, articles were screened on full text for eligibility and then assessed for risk of bias by using the Physiotherapy Evidence Database (PEDro) scale. Meta-analyses, including subgroup analysis on intervention characteristics, were conducted for the outcomes PA and physical functioning. Results: Overall, 21 RCTs totalling 2355 patients were included. The trials covered a variety of clinical areas. There was considerable heterogeneity between studies. For the 13 studies that measured PA as an outcome variable(N = 1435), a significant small positive effect in favour of the intervention was found (standardized mean difference (SMD) = 0.34; 95%CI 0.12–0.56). For the 13 studies that measured physical functioning as an outcome variable (N = 1415) no significant effect was found (SMD = 0.09; 95%CI -0.02 - 0.19). Effectiveness on PA seems to improve by providing the intervention both during and after the inpatient period and by using a theoretical model, multiple BCTs and coaching by a health professional. Conclusion: Interventions using activity trackers during and/or after inpatient care can be effective in increasing the level of PA. However, these improvements did not necessarily translate into improvements in physical functioning. Several intervention characteristics were found to increase the effectiveness of PA interventions. Trial registration: Registered in PROSPERO (CRD42020175977) on March 23th, 2020. [ABSTRACT FROM AUTHOR]
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- 2022
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6. In-Hospital Mobilization, Physical Fitness, and Physical Functioning After Lung Cancer Surgery.
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van der Leeden, Marike, Balland, Chloé, Geleijn, Edwin, Huijsmans, Rosalie J., Dekker, Joost, Paul, Marinus A., Dickhoff, Chris, and Stuiver, Martijn M.
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Apart from clinical experience and theoretical considerations, there is a lack of evidence that the level of adherence to in-hospital mobilization protocols is related to functional recovery in patients after resection for lung cancer. The objectives of the study were to determine (1) the relationship between adherence to the in-hospital mobilization protocol and physical fitness at hospital discharge and (2) the value of physical fitness measures at discharge in predicting physical functioning 6 weeks and 3 months postoperatively. This observational study included 62 patients who underwent surgical resection for lung cancer. Adherence to the in-hospital mobilization protocol was abstracted from patients' records. Physical fitness measures before the operation and at hospital discharge included handgrip strength, 30-second sit-to-stand test, and 6-minute walk test (6MWT). Self-reported physical functioning was assessed preoperatively and 6 weeks and 3 months postoperatively, using the Medical Outcome Study 36-Item Short Form (SF-36) Physical Function subscale (RAND Corp, Santa Monica, CA). Linear regression analyses were used to estimate the relationships of interest, adjusting for potential confounders. Level of adherence to the mobilization protocol was significantly and independently related to handgrip strength, sit-to-stand test, and 6MWT at discharge. Handgrip strength and 6MWT at discharge significantly predicted SF-36 Physical Function at 6 weeks and 3 months postoperatively. The sit-to-stand test only predicted SF-36 Physical Function at 6 weeks. Suboptimal postoperative mobilization after surgical resection for lung cancer negatively affects physical fitness at discharge. Our results underline the importance of adherence to early postoperative mobilization protocols. Measuring physical fitness at discharge may be useful to inform clinicians on elective referral of patients for postdischarge rehabilitation. [ABSTRACT FROM AUTHOR]
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- 2019
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7. Cost-Effectiveness of the Transmural Trauma Care Model (TTCM) for the Rehabilitation of Trauma Patients.
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Wiertsema, Suzanne H, van Dongen, Johanna M, Geleijn, Edwin, Huijsmans, Rosalie J, Bloemers, Frank W, de Groot, Vincent, and Ostelo, Raymond WJG
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Objectives: To assess the societal cost-effectiveness of the Transmural Trauma Care Model (TTCM), a multidisciplinary transmural rehabilitation model for trauma patients, compared with regular care.Methods: The economic evaluation was performed alongside a before-and-after study, with a convenience control group measured only afterward, and a 9-month follow-up. Control group patients received regular care and were measured before implementation of the TTCM. Intervention group patients received the TTCM and were measured after its implementation. The primary outcome was generic health-related quality of life (HR-QOL). Secondary outcomes included disease-specific HR-QOL, pain, functional status, and perceived recovery.Results: Eighty-three trauma patients were included in the intervention group and fifty-seven in the control group. Total societal costs were lower in the intervention group than in the control group, but not statistically significantly so (EUR-267; 95 percent confidence interval [CI], EUR-4,175-3011). At 9 months, there was no statistically significant between-group differences in generic HR-QOL (0.05;95 percent CI, -0.02-0.12) and perceived recovery (0.09;95 percent CI, -0.09-0.28). However, mean between-group differences were statistically significantly in favor of the intervention group for disease-specific HR-QOL (-8.2;95 percent CI, -15.0--1.4), pain (-0.84;95CI, -1.42--0.26), and functional status (-20.1;95 percent CI, -29.6--10.7). Cost-effectiveness acceptability curves indicated that if decision makers are not willing to pay anything per unit of effect gained, the TTCM has a 0.54-0.58 probability of being cost-effective compared with regular care. For all outcomes, this probability increased with increasing values of willingness-to-pay.Conclusions: The TTCM may be cost-effective compared with regular care, depending on the decision-makers willingness to pay and the probability of cost-effectiveness that they perceive as acceptable. [ABSTRACT FROM AUTHOR]- Published
- 2019
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8. Tailoring exercise interventions to comorbidities and treatment-induced adverse effects in patients with early stage breast cancer undergoing chemotherapy: a framework to support clinical decisions.
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van der Leeden, Marike, Huijsmans, Rosalie J., Geleijn, Edwin, de Rooij, Mariëtte, Konings, Inge R., Buffart, Laurien M., Dekker, Joost, and Stuiver, Martijn M.
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ALGORITHMS , *BREAST tumors , *CANCER chemotherapy , *CANCER patients , *EXERCISE therapy , *MEDICAL protocols , *DECISION making in clinical medicine , *COMORBIDITY - Abstract
Purpose:Delivery of exercise interventions to patients with early-stage breast cancer undergoing chemotherapy requires complex clinical decisions. The purpose of this study was to develop a framework to support clinical decisions for tailoring exercise interventions to common comorbidities and cancer treatment-induced adverse effects. Method:Tailored exercise prescriptions were developed in four steps, following the i3-S strategy. All steps were based on current best available evidence, complemented with expert opinions. First, common comorbidities and treatment-induced adverse effects were identified. In the subsequent steps, contra-indications and restrictions for exercise were described, along with possible exercise adaptations. In the final step, the obtained information was synthesized into a framework. Results:Prevalent comorbidities were hypertension, heart disease, diabetes mellitus, (osteo)arthritis, chronic obstructive pulmonary disease, and obesity. Adverse effects included conditions induced by pretreatment (e.g., lymphedema as a result of surgery) or by chemotherapy (e.g., reduced blood cell counts). Adaptations to the recommended exercise program were related to exercise tolerance, safety, and hygiene. A framework was proposed to guide clinical decisions during the exercise intervention. Conclusion:Comorbidities and adverse effects of breast cancer treatment require exercise adaptations. The proposed framework provides guidance on tailored exercise prescriptions in patients with breast cancer undergoing chemotherapy.Implications for RehabilitationExercise is recommended for patients with breast cancer undergoing chemotherapy, but requires complex clinical decisions of the health professional.We identified the most important comorbidities and adverse effects of breast cancer treatment, and the resultant contra-indications and restrictions to exercise.We incorporated these findings into a clinical decision framework that provides suggestions for exercise adaptations in patients with breast cancer undergoing chemotherapy. [ABSTRACT FROM PUBLISHER]
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- 2018
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9. The clinical utility of the GOLD classification of COPD disease severity in pulmonary rehabilitation.
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Huijsmans, Rosalie J., de Haan, Arnold, ten Hacken, Nick N.H.T., Straver, Renata V.M., and van’t Hul, Alex J.
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Summary: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has introduced a four-stage classification of chronic obstructive pulmonary disease (COPD) severity. The present study investigated the discriminatory capacity of the GOLD classification for health status outcomes in patients with COPD. An additional analysis was performed to investigate the discriminatory capacity of a multidimensional staging system, i.e. the Body-Mass Index, Degree of Airflow Obstruction and Dyspnea, and Exercise Capacity Index (BODE index) for the outcome of quality of life. Retrospective analysis was performed on 253 COPD patients (30% stage II, 48% stage III, 22% stage IV), referred for outpatient pulmonary rehabilitation. Pulmonary function, exercise capacity, dyspnoea and quality of life were evaluated. Analyses of variance were used to detect differences between GOLD stages and BODE index quartiles, and scatterplots of individual responses were produced as well. The GOLD classification discriminated between stages for pulmonary function (p<0.001), exercise capacity (p<0.001), dyspnoea (p<0.001) and the activities section (p=0.001) of the St. George Respiratory Questionnaire (SGRQ). The BODE index discriminated between quartiles for the activities section (p<0.001), impacts section (p=0.04) and the total score (p=0.01) of the SGRQ. Scatterplots revealed marked inter-individual variation within each GOLD stage or BODE index quartile, and considerable overlap between stages for all health status outcomes. These findings show that the GOLD classification indeed can be used to discern groups of COPD patients, but due to large inter-individual variability it does not seem adequate as a basis for individual management plans in rehabilitation. The BODE index appeared to discriminate slightly better for quality of life, however, it still leaves a significant part of the variance unexplained. [Copyright &y& Elsevier]
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- 2008
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10. Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: A meta-analysis
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van Tol, Benno A.F., Huijsmans, Rosalie J., Kroon, Dineke W., Schothorst, Maaike, and Kwakkel, Gert
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HEART failure patients , *EXERCISE , *PHYSICAL fitness , *QUALITY of life , *BLOOD pressure - Abstract
Abstract: Background: Despite major advances in pharmacological treatment of chronic heart failure (CHF), a number of patients still suffer from dyspnoea, fatigue, diminished exercise capacity and poor quality of life. It is in this context that exercise training is being intensively evaluated for any additional benefit in the treatment of CHF. Aims: To determine the effect of exercise training in patients with CHF on cardiac performance, exercise capacity and health-related quality of life. A meta-analysis was performed to obtain this goal. Methods and results: After including 35 randomised controlled trials, the methodological quality of each study was assessed, summary effect sizes (SESs) and the concomitant 95% confidence intervals (95% CI) were calculated for each outcome. Quantitative analysis showed statistically significant SESs, at rest, for diastolic blood pressure and end-diastolic volume. During maximal exercise, significant SESs were found for systolic blood pressure, heart rate, cardiac output, peak oxygen uptake, anaerobic threshold and 6-min walking test. The Minnesota Living with Heart Failure Questionnaire improved by an average of 9.7 points. Conclusions: Exercise training has clinically important effects on exercise capacity and HRQL, and may have small positive effects on cardiac performance during exercise. [Copyright &y& Elsevier]
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- 2006
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11. Development of a physical capacity framework to support clinical reasoning of physiotherapists treating hospitalised patients.
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van Beek, Judith, de Leeuwerk, Marijke E., van Vliet, Vincent, Huijsmans, Rosalie J., and van der Leeden, Marike
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AbstractBackgroundPurposeMethodsResultsConclusionApplying an appropriate physiotherapy intervention to a hospitalised patient can be challenging because the clinical status can change rapidly, affecting the patient’s physical capacity. Determining the appropriate type and dose of the physiotherapy intervention requires dynamic assessment of physical capacity and adequate clinical reasoning by the physiotherapist.To develop a framework for determining physical capacity to support physiotherapists in their clinical reasoning process when treating hospitalised patients.A framework was developed using a multi-method approach. First, the scientific literature was searched for existing frameworks for clinical reasoning in physiotherapy. These methods were inventoried and relevant elements were extracted. Second, a first draft of the framework was developed by a group of experts. Third, the framework was tested in practice, leading to a final version.A total of 17 frameworks were identified from the literature. No framework was found for generic use in the hospital for the purpose of determining patient’s physical capacity. Relevant elements from the identified frameworks were: the use of ICF terminology, the use of a patient management model, and frequent monitoring of clinical parameters. Field testing of the first draft of the framework led to improvement of the framework for use in clinical practice.A framework was developed to support physiotherapists in their clinical reasoning process when treating hospitalised patients. The framework can provide guidance for determining the patient’s physical capacity to allow for an adequate training stimulus. [ABSTRACT FROM AUTHOR]
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- 2024
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12. Rationale and study protocol of the Physical Activity and Dietary intervention in women with OVArian cancer (PADOVA) study: a randomised controlled trial to evaluate effectiveness of a tailored exercise and dietary intervention on body composition, physical function and fatigue in women with ovarian cancer undergoing chemotherapy.
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Stelten S, Hoedjes M, Kenter GG, Kampman E, Huijsmans RJ, van Lonkhuijzen LR, and Buffart LM
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- Body Composition, Carcinoma, Ovarian Epithelial, Exercise Therapy, Fatigue etiology, Female, Humans, Netherlands, Exercise, Ovarian Neoplasms complications, Ovarian Neoplasms drug therapy, Quality of Life
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Introduction: As a consequence of ovarian cancer and its treatment, many women with ovarian cancer have to deal with reduced physical function, fatigue, and loss of weight and/or muscle mass, compromising quality of life. Exercise and dietary interventions can positively influence body composition, physical fitness and function, and fatigue in patients with cancer. However, there are no data from randomised controlled trials on the effectiveness of exercise and dietary interventions in patients with ovarian cancer. Due to a complex disease trajectory, a relatively poor survival and distinct disease-induced and treatment-induced side effects, it is unclear whether exercise and dietary interventions that were shown to be feasible and effective in other types of cancer produce comparable results in patients with ovarian cancer. The aim of this article is to present the design of the multicentre randomised controlled Physical Activity and Dietary intervention in OVArian cancer trial and to describe how the exercise and dietary intervention is tailored to specific comorbidities and disease-induced and treatment-induced adverse effects in patients with ovarian cancer., Methods and Analysis: Adult women with primary epithelial ovarian cancer who are scheduled to undergo first-line (neo)adjuvant chemotherapy (n=122) are randomly allocated to a combined exercise and dietary intervention or a usual care control group during chemotherapy. Primary outcomes are body composition, physical function and fatigue. Outcome measures will be assessed before the start of chemotherapy, 3 weeks after completion of chemotherapy and 12 weeks later. The exercise and dietary intervention was tailored to ovarian cancer-specific comorbidities and adverse effects of ovarian cancer and its treatment following the i3-S strategy., Ethics and Dissemination: This study has been approved by the medical ethical committee of the Amsterdam UMC (reference: 018). Results of the study will be published in international peer-reviewed journals., Trial Registration Number: Netherlands Trial Registry (NTR6300)., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.)
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- 2020
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