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Objectives:The purpose of this study was to investigate the risk factors for epilepsy development following febrile seizure (FS).Methods:This study included 449 patients undergoing first FS between 2014 and 2017. The sociodemographic, clinical, and electroencephalography (EEG) characteristics of the patients were retrieved from hospital records. Patients followed-up for at least 3 years after FS were divided into two groups (epilepsy and FS group; FS only group).Results:Of the 449 patients followed-up due to FS (238 [53.2%] boys and 211 [46.8%] girls), 42 (9.4%) were diagnosed with epilepsy during follow-up. The mean age at the time of the first FS was 21.4±14.5 months. A positive family history of FS and epilepsy was observed in 217 (48.3%) and 66 (14.7%) patients, respectively. In terms of FS characteristics, the prevalence of complex FS was significantly higher in the subsequent epilepsy group. The presence of a history of perinatal asphyxia and epileptiform or background abnormality findings at first EEG was also significantly higher in the subsequent epilepsy group (p

Aim: Acute kidney injury develops as a result of various etiologies and pathological mechanisms, with a high mortality rate. This study aimed to investigate the efficacy of Anatolian syrup on histopathological variables in experimentally induced acetaminophen and lipopolysaccharide associated acute kidney injury. Methods: In this study, 5 groups were formed using 40 male Wistar albino rats (200-220g, 2-4 months old), as follows: Sham, acetaminophen (1 g/kg intraperitoneal (ip)), 3) lipopolysaccharide (5 mg/kg ip), acetaminophen (1 g/kg ip) + Anatolian syrup (15 days orally), and lipopolysaccharide (5 mg/kg ip) + Anatolian syrup (15 days orally).Tubular atrophy, tubular dilatation, cytoplasmic vacuolization in tubular epithelial cells, tubular epithelial cell necrosis, interstitial inflammation, congestion, hemorrhage, glomerular damage and loss of brushy border were evaluated histopathologically semiquantitatively using scoring from 0 to 5. Results: In histopathological variables, tubular atrophy, tubular dilatation, cytoplasmic vacuolization, necrosis, congestion, hemorrhage, glomerular damage, and loss of brushy border were significantly reduced in the acetaminophen + Anatolian syrup group compared to the acetaminophen group and in the lipopolysaccharide + Anatolian syrup group compared to the lipopolysaccharide group (p