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Your search keyword '"Jiang, Feng-Qiu"' showing total 3 results
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3 results on '"Jiang, Feng-Qiu"'

1. Decreased trap density and lower current collapse in AlGaN/GaN HEMTs by adding a magnetron-sputtered AlN gate.

Author

Jia, Mao, Zhang, He-Nan, Wang, Xiao, Liu, Chen-Yang, Pu, Tao-Fei, Wang, Ting-Ting, He, Yue, Jiang, Feng-Qiu, Fang, Ke, Yang, Ling, Bu, Yu-Yu, Li, Yang, Ma, Xiao-Hua, Ao, Jin-Ping, and Hao, Yue

Subjects
MAGNETRONS, MODULATION-doped field-effect transistors, DENSITY currents, GALLIUM nitride, MAGNETRON sputtering
Abstract

In this paper, AlN films grown by magnetron sputtering method have been proposed as the gate insulator layer of AlGaN/GaN high electron mobility transistors (HEMTs) to decrease gate leakage current and suppress the interface trap. The effect of the temperature of substrate on the quality of AlN films have been investigated. By inserting the thin AlN film (35 nm) as a gate insulator layer, the on-state resistance of AlGaN/GaN HEMTs decrease from 11.1 Ω mm to 10.3 Ω mm @ V g = 0 V, the current collapse decreases from 16.6% to 3.2%, the gate leakage can be reduced from 1.2 Ă— 10âˆ'1A mmâˆ'1 to 4.4 Ă— 10âˆ'6A mmâˆ'1 @ V g = 2 V by five orders of magnitude, and the fast interface states disappear and the normal trap density decreases from 0.96â€"1.3 Ă— 1013 cmâˆ'2eVâˆ'1 to 1.3â€"3.4 Ă— 1012 cmâˆ'2 eVâˆ'1, proving that magnetron-sputtered AlN is an effective way to improve the performance of GaN HEMTs. [ABSTRACT FROM AUTHOR]

Published
2022
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2. Role of PGI2 in the formation and maintenance of hyperdynamic circulatory state of portal hypertensive rats

Author

Xuesong Chen, Zhi-Yong Wu, Hui Cao, and Jiang-Feng Qiu

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Indomethacin, Hemodynamics, Nitric Oxide, Nitroarginine, Rats, Sprague-Dawley, chemistry.chemical_compound, Internal medicine, Hypertension, Portal, medicine, Animals, Cyclooxygenase Inhibitors, Splanchnic Circulation, Enzyme Inhibitors, Saline, business.industry, Heparin, Gastroenterology, Anticoagulants, Radioimmunoassay, General Medicine, medicine.disease, Epoprostenol, Rats, Portal System, medicine.anatomical_structure, Endocrinology, chemistry, Anesthesia, Circulatory system, Vascular resistance, cardiovascular system, Portal hypertension, lipids (amino acids, peptides, and proteins), Brief Reports, Splanchnic, business
Abstract

To investigate the role of prostacyclin (PGI(2)) and nitric oxide (NO) in the development and maintenance of hyperdynamic circulatory state of chronic portal hypertensive rats.Ninety male Sprague-Dawley rats were divided into three groups: intrahepatic portal hypertension (IHPH) group by injection of CCl(4), prehepatic portal hypertension (PHPH) group by partial stenosis of the portal vein and sham-operation control (SO) group. One week after the models were made, animals in each group were subdivided into 4 groups: saline controlled group (n = 23), Nomega-nitro-L-arginine (L-NNA) group (n = 21) group, indomethacin (INDO) group (n = 22) and high-dose heparin group (n = 24). The rats were administrated 1 mL of saline, L-NNA (3.3 mg/kg.d) and INDO (5 mg/kg.d) respectively through gastric tubes for one week, then heparin (200 IU/Kg/min) was given to rats by intravenous injection for an hour. Splanchnic and systemic hemodynamics were measured using radioactive microsphere techniques. The serum nitrate/nitrite (NO(2)(-)/NO(3)(-)) levels as a marker of production of NO were assessed by a colorimetric method, and concentration of 6-keto-PGF1alpha, a stable hydrolytic product of PGI(2), was determined by radioimmunoassay.The concentrations of plasma 6-keto-PGF1alpha (pg/mL) and serum NO(2)(-)/NO(3)(-) (micromol/L) in IHPH rats (1123.85+/-153.64, 73.34+/-4.31) and PHPH rats (891.88+/-83.11, 75.21+/-6.89) were significantly higher than those in SO rats (725.53+/-105.54, 58.79+/-8.47) (P0.05). Compared with SO rats, total peripheral vascular resistance (TPR) and spanchnic vascular resistance (SVR) decreased but cardiac index (CI) and portal venous inflow (PVI) increased obviously in IHPH and PHPH rats (P0.05). L-NNA and indomethacin could decrease the concentrations of plasma 6-keto-PGF1alpha and serum NO(2)(-)/NO(3)(-) in IHPH and PHPH rats (P0.05). Meanwhile, CI, FPP and PVI lowered but MAP, TPR and SVR increased (P0.05). After deduction of the action of NO, there was no significant correlation between plasma PGI(2) level and hemodynamic parameters such as CI, TPR, PVI and SVR. However, after deduction of the action of PGI(2), NO still correlated highly with the hemodynamic parameters, indicating that there was a close correlation between NO and the hemodynamic parameters. After administration of high-dose heparin, plasma 6-keto-PGF(1alpha) concentrations in IHPH, PHPH and SO rats were significantly higher than those in rats administrated vehicle (P0.05). On the contrary, levels of serum NO(2)(-)/NO(3)(-) in IHPH, PHPH and SO rats were significantly lower than those in rats administrated Vehicle (P0.05). Compared with those rats administrated vehicle, the hemodynamic parameters of portal hypertensive rats, such as CI and PVI, declined significantly after administration of high-dose heparin (P0.05), while TPR and SVR increased significantly (P0.05).It is NO rather than PGI(2) that is a mediator in the formation and maintenance of hyperdynamic circulatory state of chronic portal hypertensive rats.

Published
2005

3. Construction and identification of polycistron adenoviral expression vector PCA13/FasL–IRES–iNOS.

Author

Jiang Feng Qiu, Joseph C., Zhi Yong Wu, Joseph C., Chun Xia Luo, Joseph C., Fu Rong Yu, Joseph C., and Zhi Qi Zhang, Joseph C.

Subjects
*GENETIC vectors, *NITRIC oxide, *GENETICS, *RIBOSOMES, *ADENOVIRUSES, *ENTOMOLOGY
Abstract

To construct the Fas ligand (FasL) and inducible nitric oxide synthase (iNOS) coexpressed PCA13 plasmid used for packing of adenovirus, so as to observe the immunoprotective effect of FasL on the adenovirus vector. By way of the internal ribosome entry site (IRES), gene engineering techniques such as preparation and transformation of competent cells, plasmid extraction, agarose gel electrophoresis and restriction enzymolysis were used for the construction of the polycistron adenoviral expression vector PCA13/FasL–IRES–iNOS, which could coexpress FasL and the iNOS gene after multisubcloning steps. FasL and iNOS connected with the IRES were successfully cloned to the PCA13 plasmid and verified by enzymolysis (600 bp FasL, 1000 bp IRES and 4000 bp iNOS) and the gene sequence was concordant with the gene bank. The polycistron adenoviral expression vector PCA13/FasL–IRES–iNOS was successfully constructed. [ABSTRACT FROM AUTHOR]

Published
2004
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