584 results on '"Koschmieder, Steffen"'
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2. Asciminib antagonizes transplantable BCR::ABL1-positive lymphoid blast crisis in vivo by targeting malignant stem cells
3. ROP-ET: a prospective phase III trial investigating the efficacy and safety of ropeginterferon alfa-2b in essential thrombocythemia patients with limited treatment options
4. Bone marrow biopsy in geriatric patients above the age of 85 years: invaluable or unnecessary? A retrospective analysis
5. Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry
6. Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms
7. Evaluation of chiral organosulfur compounds on their activity against the malaria parasite 'Plasmodium falciparum'
8. Real-world analysis of ruxolitinib in myelofibrosis: interim results focusing on patients who were naïve to JAK inhibitor therapy treated within the JAKoMo non-interventional, phase IV trial
9. Step-in dosing of bosutinib in pts with chronic phase chronic myeloid leukemia (CML) after second-generation tyrosine kinase inhibitor (TKI) therapy: results of the Bosutinib Dose Optimization (BODO) Study
10. Validation of myeloproliferative neoplasms associated risk factor RDW as predictor of thromboembolic complications in healthy individuals: analysis on 6849 participants of the SHIP-study
11. Mast cell deficiency prevents BCR::ABL1 induced splenomegaly and cytokine elevation in a CML mouse model
12. Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms
13. Correction: Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis
14. Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis
15. Clinicohematologic and molecular response of essential thrombocythemia patients treated with pegylated interferon-α: a multi-center study of the German Study Group-Myeloproliferative Neoplasms (GSG-MPN)
16. Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche
17. Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
18. Indication and management of allogeneic haematopoietic stem-cell transplantation in myelofibrosis: updated recommendations by the EBMT/ELN International Working Group
19. Efficacy and safety of ruxolitinib in patients with newly-diagnosed polycythemia vera: futility analysis of the RuxoBEAT clinical trial of the GSG-MPN study group
20. Clonogenic assays improve determination of variant allele frequency of driver mutations in myeloproliferative neoplasms
21. Towards personalized medicine with iPS cell technology: a case report of advanced systemic mastocytosis with associated eosinophilia
22. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study
23. Mast cells as a therapeutic target in myeloproliferative neoplasms
24. CXCR4 and CD74 together enhance cell survival in response to macrophage migration-inhibitory factor in chronic lymphocytic leukemia
25. Appropriate management of polycythaemia vera with cytoreductive drug therapy: European LeukemiaNet 2021 recommendations
26. Second versus first wave of COVID-19 in patients with MPN
27. Breakthrough infections in MPN-COVID vaccinated patients
28. Early and late stage MPN patients show distinct gene expression profiles in CD34+ cells
29. Direct oral anticoagulants for myeloproliferative neoplasms: results from an international study on 442 patients
30. Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches
31. Germline variants in DNA repair genes, including BRCA1/2, may cause familial myeloproliferative neoplasms
32. Unmet clinical needs in the management of CALR-mutated essential thrombocythaemia: a consensus-based proposal from the European LeukemiaNet
33. A paradigm shift in cancer nanomedicine: from traditional tumor targeting to leveraging the immune system
34. Inflammatory Responses of Astrocytes Are Independent from Lipocalin 2
35. Potential Technologies Review: A Hybrid Information Retrieval Framework to Accelerate Demand-Pull Innovation in Biomedical Engineering
36. High mortality rate in COVID-19 patients with myeloproliferative neoplasms after abrupt withdrawal of ruxolitinib
37. Macrophage frequency in the bone marrow correlates with morphologic subtype of myeloproliferative neoplasm
38. Myelofibrosis: Current unmet needs, emerging treatments, and future perspectives.
39. Safety and efficacy of the combination of sonidegib and ruxolitinib in myelofibrosis: a phase 1b/2 dose-finding study
40. Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study
41. Therapeutic inhibition of FcγRIIb signaling targets leukemic stem cells in chronic myeloid leukemia
42. JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms
43. Frequency of infections in 948 MPN patients: a prospective multicenter patient-reported pilot study
44. Hypoxia-inducible factor 1 (HIF-1) is a new therapeutic target in JAK2V617F-positive myeloproliferative neoplasms
45. Transcriptional alteration of DNA repair genes in Philadelphia chromosome negative myeloproliferative neoplasms
46. Dexamethasone nanomedicines for COVID-19
47. Tyrosine kinase inhibitor–induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors
48. Among classic myeloproliferative neoplasms, essential thrombocythemia is associated with the greatest risk of venous thromboembolism during COVID-19
49. Recent advances in the genomics and therapy of BCR/ABL1-positive and -negative chronic myeloproliferative neoplasms
50. Stem cell persistence in CML is mediated by extrinsically activated JAK1-STAT3 signaling
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