1. Iridoids and Anthraquinones from the Malaysian Medicinal Plant, Saprosma scortechinii (Rubiaceae)
- Author
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Sui-Kiong Ling, Kunihide Mihashi, Takashi Tanaka, Akiko Komorita, Toshihiro Fujioka, and Isao Kouno
- Subjects
Saprosma scortechinii ,Iridoid ,medicine.drug_class ,Anthraquinones ,Rubiaceae ,Terpene ,chemistry.chemical_compound ,Glucoside ,sulfur-containing iridoid ,Drug Discovery ,medicine ,bis-iridoid glucoside ,Organic chemistry ,Iridoids ,Phenols ,Saprosma ,chemistry.chemical_classification ,Plants, Medicinal ,Plant Stems ,biology ,Plant Extracts ,Malaysia ,Glycoside ,General Chemistry ,General Medicine ,biology.organism_classification ,Terpenoid ,Plant Leaves ,chemistry ,anthraquinone - Abstract
A further investigation of the leaves and stems of Saprosma scortechinii afforded 13 compounds, of which 10 are new compounds. These were elucidated as the bis-iridoid glucosides, saprosmosides G (1) and H (2), the iridoid glucoside, 6-O-epi-acetylscandoside (3), and the anthraquinones, 1-methoxy-3-hydroxy-2-carbomethoxy-9,10-anthraquinone (4), 1-methoxy-3-hydroxy-2-carbomethoxy-9,10-anthraquinone 3-O-β-primeveroside (5), 1,3-dihydroxy-2-carbomethoxy-9,10-anthraquinone 3-O-β-primeveroside (6), 1,3,6-trihydroxy-2-methoxymethyl-9,10-anthraquinone (7), 1-methoxy-3,6-dihydroxy-2-hydroxymethyl-9,10-anthraquinone (8), 1,3,6-trihydroxy-2-hydroxymethyl-9,10-anthraquinone 3-O-β-primeveroside (9), and 3,6-dihydroxy-2-hydroxymethyl-9,10-anthraquinone (10). Structure assignments for all compounds were established by means of mass and NMR spectroscopies, chemical methods, and comparison with published data. The new anthraquinones were derivatives of munjistin and lucidin., Chemical & Pharmaceutical Bulletin v.50(8) p.1035-1040, 2002
- Published
- 2002