1. The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task
- Author
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Wilson, R. P., Colizzi, M., Bossong, M. G., Allen, P., Kempton, M., Abe, N., Barros-Loscertales, A. R., Bayer, J., Beck, A., Bjork, J., Boecker, R., Bustamante, J. C., Choi, J. S., Delmonte, S., Dillon, D., Figee, M., Garavan, H., Hagele, C., Hermans, E. J., Ikeda, Y., Kappel, V., Kaufmann, C., Lamm, C., Lammertz, S. E., Li, Y., Murphy, A., Nestor, L., Pecina, M., Pfabigan, D., Pizzagalli, D., Rademacher, L., Admon, R., Sommer, T., Stark, R., Suzuki, H., Van Amelsvoort, T., Van Hell, E., Vink, M., Votinov, M., Wotruba, D., and Bhattacharyya, S.
- Subjects
Neural substrate ,1702 Cognitive Sciences ,Review ,Striatum ,Monetary incentive delay task ,Anticipation ,03 medical and health sciences ,0302 clinical medicine ,Reward ,medicine ,Humans ,Valence (psychology) ,Brain Mapping ,Motivation ,Anticipation or reward ,fMRI ,Healthy adults ,Meta-analysis ,Anticipation, Psychological ,Nerve Net ,Magnetic Resonance Imaging ,MTAC ,Neuropsychology ,Experimental Psychology ,Human brain ,030227 psychiatry ,Neuropsychology and Physiological Psychology ,Incentive ,medicine.anatomical_structure ,1701 Psychology ,Psychological ,Psychology ,1109 Neurosciences ,Neuroscience ,030217 neurology & neurosurgery - Abstract
The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain. Electronic supplementary material The online version of this article (10.1007/s11065-018-9385-5) contains supplementary material, which is available to authorized users.
- Published
- 2018