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Your search keyword '"Leibowitz, Andrew B."' showing total 112 results
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4. In Reply

Author

Poeran, Jashvant, Memtsoudis, Stavros G., Mazumdar, Madhu, and Leibowitz, Andrew B.

Published
2019
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9. Differential ventilation using flow control valves as a potential bridge to full ventilatory support during the COVID-19 crisis

Author

Levin, Matthew, Chen, Martin D, Shah, Anjan, Shah, Ronak, Zhou, George, Kane, Erica, Burnett, Garrett, Ranginwala, Shams, Madek, Jonathan, Gidiscin, Christopher, Park, Chang, Katz, Daniel, Salter, Benjamin, Kohli-Seth, Roopa, Eisenkraft, James B, Uysal, Suzan, McCarry, Michael, Leibowitz, Andrew B, and Reich, David L

Abstract

Background: It has been projected that there will be too few ventilators to meet demand during the COVID-19 (SARS CoV-2) pandemic. Ventilator sharing has been suggested as a crisis standard of care strategy to increase availability of mechanical ventilation. The safety and practicality of shared ventilation in patients is unknown. We designed and evaluated a system whereby one mechanical ventilator can be used to simultaneously ventilate two patients who have different lung compliances using a custom manufactured flow control valve to allow for individual adjustment of tidal volume and airway pressure for each patient. Methods: The system was first evaluated in a simulation lab using two human patient simulators under expected clinical conditions. It was then tested in an observational study of four patients with acute respiratory failure due to COVID-19. Two separately ventilated COVID-19 patients were connected to a single ventilator for one hour. This intervention was repeated in a second pair of patients. Ventilatory parameters (tidal volume, peak airway pressures, compliance) were recorded at five minute intervals during both studys. Arterial blood gases were taken at zero, thirty, and sixty minutes. The primary outcome was maintenance of stable acid-base status and oxygenation during shared ventilation. Results: Two male and two female patients, age range 32-56 yrs, participated. Ideal body weight and driving pressure were markedly different among patients. All patients demonstrated stable physiology and ventilation for the duration of shared ventilation. In one patient tidal volume was increased after 30 minutes to correct a respiratory acidosis. Conclusions: Differential ventilation using a single ventilator and a split breathing circuit with flow control valves is possible. A single ventilator could feasibly be used to safely ventilate two COVID-19 patients simultaneously as a bridge to full ventilatory support.

Published
2020
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23. Contributors

Author

Bassily-Marcus, Adel M., Beilin, Yaakov, Bejar, Lucas, Bernstein, Howard H., Bhatt, Himani, Bialos, Michael T., Brand, Jordan, Bryson, Ethan O., Capan, Levon M., Castillo, Maria D., Chietero, Michael, Chung, Insung, Davis, Renee L., Deiner, Stacie G., deLeon, Isabelle, DeMaria, Samuel, Jr., Dilos, Barbara M., Eisenkraft, James B., Epstein, Jason H., Evans, Adam, Fischer, Gregory W., Freedman, Gordon M., Gainsburg, Daniel M., Gettes, Mark, Gooden, Cheryl K., Hausman, Laurence M., Hollinger, Ingrid B., Hosseinian, Leila, Hyman, Jaime B., Kahn, Ronald A., Kaufman, Margit, Kellner, Charles H., Khelemsky, Yury, Koppel, James N., Kreitzer, Joel M., Lai, Yan H., Lazar, Michael, Leibowitz, Andrew B., Levine, Adam I., Lipson, Scott D., Marn, Richard Y., Mathney, Edward R., Miller, Sanford, Mittnacht, Alexander J.C., Neustein, Steven M., Osborn, Irene P., Outterson, Rachel E., Perez, Andrew M., Reed, Allan P., Reich, David L., Rhee, Amanda J., Roccaforte, J. David, Rodriguez-Diaz, Cesar, Rosenblatt, Meg A., Roth, Ram, Schwartz, Arthur E., Sebeo, Joseph, Segal, Barry J., Serban, Stelian I., Sim, Alan J., Sittler, Patrick L., Stone, Marc E., Sutin, Kenneth M., Thomas, Vinoo, Trigo, Paula, Trinh, Muoi A., Tulman, Gene, Usenko, Jaroslav, Velasquez, Elvis Umanzor, Wallace, Terence, Wax, David B., Weiner, Menachem M., and Yudkowitz, Francine S.

Published
2014
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25. A Multicenter Study of Physicians' Knowledge of the Pulmonary Artery Catheter.

Author

Iberti, Thomas J., Fischer, Ellen P., Leibowitz, Andrew B., Panacek, Edward A., Silverstein, Jeffrey H., and Albertson, Timothy E.

Subjects
CATHETERS, INTERVENTIONAL radiology equipment, DRUG delivery devices, PHYSICIANS, MEDICAL personnel
Abstract

Presents a multicenter study of physicians' knowledge of the pulmonary artery catheter (PAC). Information on PAC; Modified response options for PAC study questionnaire; Results of the study.

Published
1990
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29. Perform Bilateral Vascular Ultrasound Before Inserting a Central Line.

Author

Leibowitz, Andrew B.

Subjects
*CATHETERIZATION, *RESEARCH, *MEDICAL research, *DIAGNOSIS
Abstract

The author discusses the clinical research performed to maximize the odds of catheterization success in the small subset of difficult patients. The research is described to have not been clear in presenting what percentage of patients the proportional cross-sectional area difference between left and right sides would affect the likelihood of success. He believes that examining both the left and right infraclavicular veins can yield crucial information for the practitioner.

Published
2013
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30. Hypovolemia is not a common cause of acute kidney injury.

Author

Leibowitz, Andrew B., Dennen, Paula, Douglas, Ivor, and Anderson, Robert

Subjects
*LETTERS to the editor, *KIDNEY injuries, *INTENSIVE care units, *CRITICAL care medicine, *RENAL intensive care
Abstract

Two letters to the editor are presented concerning the article "Acute Kidney Injury in the Intensive Care Unit: An Update and Primer for the Intensivists," by P. Dennen and colleagues, published in the 2010 issue, including a comment and the authors' reply.

Published
2010
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31. Pulmonary artery catheter determined right ventricular ejection fraction and right ventricular end-diastolic volume: Another case of "The Emperor Has No Clothes".

Author

Leibowitz, Andrew B.

Subjects
*CRITICAL care medicine, *PULMONARY artery catheters, *CATHETERIZATION, *RIGHT heart ventricle diseases, *DIASTOLE (Cardiac cycle), *ISCHEMIA diagnosis
Abstract

The author reflects on the need to properly document the effectiveness of pulmonary artery catheterization (PAC) for critically ill patients. He states that PAC determined the accuracy of right ventricular end-diastolic volume (RVEDV) and the right ventricular ejection fraction (RVEF), however, a study concluded that PAC is not accurate and it is very low to diagnose heart failure and ischemia. He notes that RVEDV and RVEF methods are poor for the catheterization.

Published
2009
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32. Is transpulmonary thermodilution cardiac output measurement an advance, or just another technique in search of an application?

Author

Leibowitz, Andrew B.

Subjects
*HEART failure, *PULMONARY artery, *CARDIAC output, *CRITICAL care medicine
Abstract

The article comments on the paper "Comparison of pulmonary artery and aortic transpulmonary thermodilution for monitoring cardiac output in patients with severe heart failure: Validation of a novel method," by S. Friesecke and colleagues. According to the author, the study addresses whether or not PiCCO, a method of cardiac output (CO) determination in patients with severe congestive heart failure, equals the CO determined using the pulmonary artery catheter (PAC).

Published
2009
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33. Persistent preoxygenation efforts before tracheal intubation in the intensive care unit are of no use: Who would have guessed?

Author

Leibowitz, Andrew B.

Subjects
*OXYGEN therapy, *INTUBATION, *ARTIFICIAL respiration, *CRITICALLY ill, *CRITICAL care medicine
Abstract

The article comments on the paper "Extending the preoxygenation period from 4 to 8 mins in critically ill patients undergoing emergency intubation," by T.C. Mort and colleagues. According to the author, the study supports the physiologic prediction that a combination of shunt and denitrogenation failure is detrimental in patients undergoing emergency tracheal intubation. He believes the next step should shift from preoxygenation efforts and instead focus on the best method to do intubation.

Published
2009
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34. More reliable determination of central venous and pulmonary artery occlusion pressures: does it matter?

Author

Leibowitz, Andrew B

Subjects
*LEFT heart ventricle, *PULMONARY artery physiology, *AIRWAY (Anatomy), *ARTIFICIAL respiration, *BLOOD pressure, *BLOOD volume, *CENTRAL venous pressure, *CRITICAL care medicine, *HEART physiology, *LUNGS, *LUNG injuries, *PATIENT monitoring, *PROGNOSIS, *RESPIRATORY measurements, *ADULT respiratory distress syndrome, *RESEARCH bias, RESEARCH evaluation
Published
2005
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