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46. Relationships Between Family Resilience, Individual Resilience, and Quality of Life in Patients with Head and Neck Cancer: A Cross-Sectional Study.

Author

Liu, Yuan-Yuan, Shen, Xia, Yang, Fei, Song, Shao Zheng, and Huang, Jian Feng

Subjects
*FAMILIES & psychology, *PSYCHOLOGICAL resilience, *CROSS-sectional method, *PEARSON correlation (Statistics), *OPTIMISM, *HEAD & neck cancer, *STATISTICAL sampling, *QUESTIONNAIRES, *TERTIARY care, *STRUCTURAL equation modeling, *DESCRIPTIVE statistics, *FAMILY relations, *PROBLEM solving, *QUALITY of life, *COMMUNICATION, *CANCER patient psychology, *CONFIDENCE intervals
Abstract

Background: Patients with head and neck cancer (HNC) have to cope with a multitude of treatment-related adverse effects that impact their quality of life (QoL) post-treatment completion. The presence of family resilience could potentially foster individual resilience and might contribute to patients' QoL. However, this interconnection has not been confirmed. Objective: To explore the relationships between family resilience, individual resilience, and QoL in patients with HNC and to determine whether individual resilience in HNC patients functions as a mediator between family resilience and QoL. Methods: From September 2022 to June 2023, a cross-sectional survey was conducted among 185 patients with HNC recruited through convenience sampling from a tertiary care hospital in Jiangsu Province, China. Self-report measures of family resilience, individual resilience, and QoL were assessed. Relationships were examined by Pearson's correlations. Structural equation models were used to assess whether individual resilience played a mediating role between family resilience and QoL. Results: There were significant positive correlations between QoL and both family resilience (r = 0.43, P <.01) and individual resilience (r = 0.59, P <.01). Moreover, family resilience had an indirect influence on QoL through its effect on individual resilience (β = 0.319, 95% CI: 0.336-0.815). Conclusion: Family resilience emerges as a significant positive factor capable of enhancing QoL for patients with HNC by bolstering their resilience. To mitigate the detrimental effects of inadequate individual resilience on QoL of patients with HNC, it is advised to implement interventions focused on enhancing family resilience. China Clinical Trials Registry number: ChiCTR2300067612 [ABSTRACT FROM AUTHOR]

Published
2024
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48. Electrochemical C3‐Fluoroalkoxylation of Quinoxalin‐2(1H)‐ones with Fluoroalkyl Alcohols for the Synthesis of 3‐Fluoroalkoxylated Quinoxalin‐2(1H)‐ones.

Author

Liu, Yuan‐Yuan, Chen, Lu, Wang, Ting, Wang, Guoqin, Zhang, Minmin, Jing, Linhai, Han, Pan, and Zhang, Zheng‐Bing

Subjects
*RADICALS (Chemistry), *FRIENDSHIP
Abstract

Herein, we report the first electricity‐driven and metal‐free C(3)−H fluoroalkoxylation of quinoxalin‐2(1H)‐ones with both α‐monosubstituted and α,α‐disubstituted fluoroalkyl alcohols. This strategy features the advantages of convenience, mildness, effEctiveness and broad substrate practicality for synthesizing a new type of 3‐fluoroalkoxylated quinoxalin‐2(1H)‐ones. [ABSTRACT FROM AUTHOR]

Published
2024
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