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In the cases presented herein, the TIA episode occurred in the setting of a long history of migraine. Our findings suggest that in a sample of Southern Italy population, aPL are independently associated with the risk for TIA episode.

We investigated the activated partial thromboplastin time prolongation after addition to citrated plasma of a heparin-antithrombin mixture, expressed as the ratio of the APTT carried out in the presence of the heparin mixture divided by the baseline APTT of the same plasma mixture. Thrombophilia defects are recognized in about one third of the patients presenting with a venous thromboembolic event.

Bechet's disease may be considered an immune-mediated vasculitis involving vessels of all size. We would like to suggest that Bechet's disease should be considered as a prethrombotic state. Howerer, we feel that the hypercoagulable/prethrombotic state of the Bechet's disease remains to be elucidaded.