230 results on '"Machida, Keigo"'
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2. MSI2 promotes translation of multiple IRES-containing oncogenes and virus to induce self-renewal of tumor initiating stem-like cells
3. Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis
4. Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
5. LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells
6. c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
7. The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein
8. NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells.
9. Hepatitis C Virus Induces a Mutator Phenotype: Enhanced Mutations of Immunoglobulin and Protooncogenes
10. p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs
11. NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism
12. Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance
13. Existence of cancer stem cells in hepatocellular carcinoma: myth or reality?
14. Profiling of Circulating Tumor Cells for Screening of Selective Inhibitors of Tumor‐Initiating Stem‐Like Cells.
15. GRP78 Inhibitor YUM70 Suppresses SARS-CoV-2 Viral Entry, Spike Protein Production and Ameliorates Lung Damage.
16. TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome
17. Loss of the transforming growth factor‐β effector β2‐Spectrin promotes genomic instability
18. Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells
19. State of the art treatment of HBV hepatocellular carcinoma and the role of HBsAg post liver transplantation and resection
20. Hepatitis C Virus Infection of T Cells Inhibits Proliferation and Enhances Fas-Mediated Apoptosis by Down-Regulating the Expression of CD44 Splicing Variant 6
21. Toll-Like Receptor 4 Mediates Synergism between Alcohol and HCV in Hepatic Oncogenesis Involving Stem Cell Marker Nanog
22. Alcohol, TLR4-TGF-β antagonism, and liver cancer
23. Oncogenic signaling pathways and origins of tumor-initiating stem-like cells of hepatocellular carcinomas induced by hepatitis C virus, alcohol and/or obesity
24. NUMB Phosphorylation Destabilizes p53 and Promotes Self-Renewal of Tumor-Initiating Cells by a NANOG-Dependent Mechanism in Liver Cancer
25. Protocol for generation of humanized HCC mouse model and cancer-driver mutations using CRISPR-Cas9
26. Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice
27. Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells
28. Tumor-initiating stem-like cells and drug resistance: carcinogenesis through Toll-like receptors, environmental factors, and virus
29. Lymphotropic HCV strain can infect human primary naïve CD4+ cells and affect their proliferation and IFN-γ secretion activity
30. Activated and nonactivated MSCs increase survival in humanized mice after acute liver injury through alcohol binging.
31. Immunotherapy and Microbiota for Targeting of Liver Tumor-Initiating Stem-like Cells.
32. HEPATOCYTE NOX PROTEINS IN CHRONIC HEPATITIS C AND HEPATOCELLULAR CARCINOMA: P6
33. A review of alcohol–pathogen interactions: New insights into combined disease pathomechanisms.
34. State of the art treatment of hepatitis B virus hepatocellular carcinoma and the role of hepatitis B surface antigen post‐liver transplantation and resection.
35. Detection of a new genotype 1b lymphotropic HCV strain and analysis of Th17 commitment: 1040
36. Morphogens and hepatic stellate cell fate regulation in chronic liver disease
37. Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus
38. Alcohol and Hepatitis C Virus-Interactions in Immune Dysfunctions and Liver Damage
39. “Second Hit” Models of Alcoholic Liver Disease
40. HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice
41. Loss of the TGF-β Effector β2SP Promotes Genomic Instability
42. Pluripotency Transcription Factors and Metabolic Reprogramming of Mitochondria in Tumor-Initiating Stem-like Cells.
43. c-Jun mediates HCV hepatocarcinogenesis through STAT3 and nitric oxide-dependent impairment of oxidative DNA repair
44. TLRs, Alcohol, HCV, and Tumorigenesis
45. Extrahepatic Replication of HCV.
46. TLR4-Dependent Tumor-Initiating Stem Cell-Like Cells (TICs) in Alcohol-Associated Hepatocellular Carcinogenesis.
47. Tu1631 A TGF-β-Ctcf Regulated Pathway Suppresses Stem Cell Associated Tumor Progression
48. TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice.
49. Smad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma.
50. Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure.
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