265 results on '"McGranahan, Nicholas"'
Search Results
2. Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling
3. Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models
4. Decoding the interplay between genetic and non-genetic drivers of metastasis
5. The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance
6. CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction
7. Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx
8. Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion
9. ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA
10. Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing
11. Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology
12. Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
13. Antibodies against endogenous retroviruses promote lung cancer immunotherapy
14. The evolution of non-small cell lung cancer metastases in TRACERx
15. The evolution of lung cancer and impact of subclonal selection in TRACERx
16. Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA
17. Genomic–transcriptomic evolution in lung cancer and metastasis
18. Lung adenocarcinoma promotion by air pollutants
19. Evolutionary characterization of lung adenocarcinoma morphology in TRACERx
20. Body composition and lung cancer-associated cachexia in TRACERx
21. A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer
22. Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer
23. Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution
24. The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner
25. Challenges and opportunities in 2021
26. Using DNA sequencing data to quantify T cell fraction and therapy response
27. Potential Use of Shared Frameshift Mutations in ‘Off-the-Shelf’ Neoantigen Vaccines
28. Genetic and non-genetic clonal diversity in cancer evolution
29. Promises and challenges of adoptive T-cell therapies for solid tumours
30. Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner
31. Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas
32. Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
33. Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features
34. Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer
35. Pervasive chromosomal instability and karyotype order in tumour evolution
36. The T cell differentiation landscape is shaped by tumour mutations in lung cancer
37. Understanding the impact of immune-mediated selection on lung cancer evolution
38. Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse
39. Neoantigen-directed immune escape in lung cancer evolution
40. Neoantigen-reactive [CD8.sup.+] T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma
41. Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity
42. MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically
43. Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
44. Chromosomal instability drives metastasis through a cytosolic DNA response
45. Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
46. The evolution of lung cancer and impact of subclonal selection in TRACERx
47. Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
48. Inferring mutational timing and reconstructing tumour evolutionary histories
49. Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
50. Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
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