216 results on '"Neidhardt J"'
Search Results
2. Localizing the RPGR protein along the cilium: a new method to determine efficacies to treat RPGR mutations
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Da Costa, R, Glaus, E, Tiwari, A, Kloeckener-Gruissem, B, Berger, W, and Neidhardt, J
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- 2015
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3. Influence of phase transition on the tribological performance of arc-evaporated AlCrVN hard coatings
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Franz, R., Neidhardt, J., Kaindl, R., Sartory, B., Tessadri, R., Lechthaler, M., Polcik, P., and Mitterer, C.
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- 2009
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4. The nanostructure, wear and corrosion performance of arc-evaporated CrB xN y nanocomposite coatings
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Polychronopoulou, K., Baker, M.A., Rebholz, C., Neidhardt, J., O'Sullivan, M., Reiter, A.E., Kanakis, K., Leyland, A., Matthews, A., and Mitterer, C.
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- 2009
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5. Spectroscopic ellipsometry characterization of amorphous carbon and amorphous, graphitic and fullerene-like carbon nitride thin films
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Berlind, T., Furlan, A., Czigany, Zs., Neidhardt, J., Hultman, L., and Arwin, H.
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- 2009
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6. Structure–property relations of arc-evaporated Al–Cr–Si–N coatings
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Soldán, J., Neidhardt, J., Sartory, B., Kaindl, R., Čerstvý, R., Mayrhofer, P.H., Tessadri, R., Polcik, P., Lechthaler, M., and Mitterer, C.
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- 2008
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7. Effect of nitrogen-incorporation on structure, properties and performance of magnetron sputtered CrB 2
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Budna, K.P., Mayrhofer, P.H., Neidhardt, J., Hegedũs, É., Kovács, I., Tóth, L., Pécz, B., and Mitterer, C.
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- 2008
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8. Formation mechanisms of low-friction tribo-layers on arc-evaporated TiC 1− xN x hard coatings
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Rebelo de Figueiredo, M., Neidhardt, J., Kaindl, R., Reiter, A., Tessadri, R., and Mitterer, C.
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- 2008
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9. Synthesis–structure–property relations for Cr–B–N coatings sputter deposited reactively from a Cr–B target with 20 at% B
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Budna, K.P., Neidhardt, J., Mayrhofer, P.H., and Mitterer, C.
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- 2008
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10. Thermal decomposition routes of CrN hard coatings synthesized by reactive arc evaporation and magnetron sputtering
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Ernst, W., Neidhardt, J., Willmann, H., Sartory, B., Mayrhofer, P.H., and Mitterer, C.
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- 2008
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11. Micro- and bonding structure of arc-evaporated AlCrVN hard coatings
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Franz, R., Neidhardt, J., Sartory, B., Tessadri, R., and Mitterer, C.
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- 2008
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12. Synthesis and characterization of Cr–B–N coatings deposited by reactive arc evaporation
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Polychronopoulou, K., Neidhardt, J., Rebholz, C., Baker, M.A., O’Sullivan, M., Reiter, A.E., Gunnaes, A.E., Giannakopoulos, K., and Mitterer, C.
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- 2008
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13. Low-Friction Mechanisms Active for Carbon Containing Coatings: Ti-C-N as a Model System
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Rebelo de Figueiredo, M., Neidhardt, J., Franz, R., and Mitterer, C.
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- 2008
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14. Semi-quantitative chemical analysis of hard coatings by Raman micro-spectroscopy: the aluminium chromium nitride system as an example
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Kaindl, R., Sartory, B., Neidhardt, J., Franz, R., Reiter, A., Polcik, P., Tessadri, R., and Mitterer, C.
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- 2007
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15. High-temperature low-friction properties of vanadium-alloyed AlCrN coatings
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Franz, R., Neidhardt, J., Sartory, B., Kaindl, R., Tessadri, R., Polcik, P., Derflinger, V. H., and Mitterer, C.
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- 2006
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16. Electrical properties of carbon nitride thin films: Role of morphology and hydrogen content
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Broitman, E., Hellgren, N., Neidhardt, J., Brunell, I., and Hultman, L.
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- 2002
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17. Structure–property–performance relations of high-rate reactive arc-evaporated Ti–B–N nanocomposite coatings
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Neidhardt, J., O'Sullivan, M., Reiter, A.E., Rechberger, W., Grogger, W., and Mitterer, C.
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- 2006
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18. Diagnostics of N2/Ar direct current magnetron discharge for reactive sputter deposition of fullerene-like carbon nitride thin films
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Neidhardt, J., Hultman, L., Abendroth, B., Gago, R., and Moller, W.
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Nitrogen -- Atomic properties ,Carbon -- Atomic properties ,Dielectric films -- Electric properties ,Thin films -- Electric properties ,Physics - Abstract
Plasma probe measurements and energy selective mass spectrometry are used to characterize the composition and energetic conditions of the ion flux of a direct current, N2/Ar, unbalanced magnetron sputtering plasma in front of a graphite target, depending on the total pressure and gas composition. The findings show that besides C and N atoms and ions, other species, like preformed C(sub x)N(sub y) particles, play an important role during growth of fullerene-like (FL) carbon nitride (CN(sub x)) thin films.
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- 2003
19. Structure and properties of pulsed-laser deposited carbon nitride thin films
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Riascos, H., Neidhardt, J., Radnóczi, G.Z., Emmerlich, J., Zambrano, G., Hultman, L., and Prieto, P.
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- 2006
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20. Annealing studies of nanocomposite Ti–Si–C thin films with respect to phase stability and tribological performance
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Rester, M., Neidhardt, J., Eklund, P., Emmerlich, J., Ljungcrantz, H., Hultman, L., and Mitterer, C.
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- 2006
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21. Water adsorption on lubricated fullerene-like CN x films
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Broitman, E., Pushkarev, V.V., Gellman, A.J., Neidhardt, J., Furlan, A., and Hultman, L.
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- 2006
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22. Nanoindentation response of high performance fullerene-like CN x
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Palacio, J.F., Bull, S.J., Neidhardt, J., and Hultman, L.
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- 2006
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23. Review and evaluation of anatomy sites on the Internet (updated 1999)
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Frasca, D., Malezieux, R., Mertens, P., Neidhardt, J. P. H., and Voiglio, E. J.
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- 2000
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24. Prospecting and evaluation of the anatomy sites on the internet
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Voiglio, E. J., Frasca, D., Malezieux, R., Moreau, S., Rodier, M. N., and Neidhardt, J. P. H.
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- 1999
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25. Gastrocolic vein: Definition and report of two cases of avulsion
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Voiglio, E. J., du Retail, C. Boutillier, Neidhardt, J. P. H., Caillot, J. L., Barale, F., and Mertens, P.
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- 1998
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26. Cryogenic deposition of carbon nitride thin solid films by reactive magnetron sputtering; suppression of the chemical desorption processes
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Neidhardt, J., Högberg, H., and Hultman, L.
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- 2005
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27. Synthesis of carbon nitride thin films by low-energy ion beam assisted evaporation: on the mechanisms for fullerene-like microstructure formation
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Gago, R., Neidhardt, J., Vinnichenko, M., Kreissig, U., Czigány, Zs., Kolitsch, A., Hultman, L., and Möller, W.
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- 2005
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28. First-principles calculations on the curvature evolution and cross-linkage in carbon nitride
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Gueorguiev, G.K., Neidhardt, J., Stafström, S., and Hultman, L.
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- 2005
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29. Rare variants in the GABAA receptor subunit ? identified in patients with a wide spectrum of epileptic phenotypes
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van Markus, F, Angelini, C, Trimouille, A, Rudolf, G, Lesca, G, Goizet, C, Lasseaux, E, Arveiler, B, van Slegtenhorst, Marjon, Brooks, Alice, Abou Jamra, R, Korenke, GC, Neidhardt, J, Owczarek-Lipska, M, and Clinical Genetics
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- 2020
30. Adapting to an emerging social media landscape: The rise of informalization of company communication in tourism
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Dijkmans, Corné, Kerkhof, P, Beukeboom, C.J., Neidhardt, J, Wörndl, W, Academy for Tourism, Digitisation in Tourism, Communication Science, Network Institute, Communication Choices, Content and Consequences (CCCC), Neidhardt, Julia, and Wörndl, Wolfgang
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Emoji ,social media ,05 social sciences ,Advertising ,SDG 8 - Decent Work and Economic Growth ,emoticons ,informalization of communication ,emoji ,conversational human voice ,Expression (architecture) ,0502 economics and business ,textual paralanguage ,050211 marketing ,Relevance (information retrieval) ,Social media ,Business ,050203 business & management ,Tourism - Abstract
This study investigates the evolvement of informalization of company communication on social media over time, based on actual social media data from the tourism industry. The development in the use of emoticons and emoji by companies is examined, as an expression of informalization and humanization of online company communication. We selected 33 companies from the tourism industry in The Netherlands and investigated their Facebook and Twitter messages supplemented with the messages of consumers who interacted with these companies, for the period 2011–2016. Results show that the use of emoticons and emoji in online company communication increased significantly over the period covered in this study, demonstrating a higher level of informalization of company communication. Since this is a key factor for improving relational outcomes, this finding has scholarly as well as managerial relevance. We discuss the implications of the results for the presence of organizations on social media.
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- 2020
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31. Structural, mechanical and tribological behavior of fullerene-like and amorphous carbon nitride coatings
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Neidhardt, J., Hultman, L., Broitman, E., Scharf, T.W., and Singer, I.L.
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- 2004
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32. Correlated high resolution transmission electron microscopy and X-ray photoelectron spectroscopy studies of structured CN x (0 < x < 0.25) thin solid films
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Neidhardt, J., Hultman, L., and Czigány, Zs.
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- 2004
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33. French mirror site of the NPAC Visible Human Viewer: first year evaluation
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Voiglio, E. J., Frattini, B., Romeuf, D., Morin, A., Neidhardt, J. P. H., and Laville, M.
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- 1999
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34. Imaging of fullerene-like structures in CN x thin films by electron microscopy; sample preparation artefacts due to ion-beam milling
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Czigány, Zs., Neidhardt, J., Brunell, I.F., and Hultman, L.
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- 2003
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35. Transmission electron microscopy studies and simulation of the indentation response of superelastic fullerenelike carbon nitride thin films.
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Neidhardt, J., Walter, C., Molina-Aldareguia, J. M., Herrmann, M., Clegg, W. J., and Hultman, L.
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TRANSMISSION electron microscopy , *MICROSTRUCTURE , *STEREOLOGY , *THIN films , *COATING processes - Abstract
The highly elastic behavior of fullerenelike carbon nitride thin films on single crystal Si (001) substrates has been studied by nanoindentation. The films exhibit a microstructure of frequently bent and intersecting graphene sheets. Transmission electron microscopy of indented areas revealed no tendency to plastic deformation in the highly elastic and compliant film. Also, a unique deformation pattern in the Si substrate is observed, where a {111} facetted inverted pyramid of untransformed Si remained intact under the indenter with a retained CNx/Si(001) interface. Analytical approaches using the effective indenter method, supported by finite element methods, are employed to understand the nonlinear but fully elastic behavior of the coatings as well as to describe the critical parameters for the deformation and phase transformation of the Si substrate. [ABSTRACT FROM AUTHOR]
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- 2008
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36. Diagnostics of a N[sub 2]/Ar direct current magnetron discharge for reactive sputter deposition of fullerene-like carbon nitride thin films.
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Neidhardt, J., Hultman, L., Abendroth, B., Gago, R., and Möller, W.
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NONMETALS , *MASS spectrometry , *MASS (Physics) , *DIRECT currents , *PHYSICS - Abstract
Plasma probe measurements and energy selective mass spectrometry were used to characterize the composition and energetic conditions of the ion flux of a direct current, N[sub 2]/Ar, unbalanced magnetron sputtering plasma in front of a graphite target, depending on the total pressure and gas composition. It is shown that the flux of ionized film-forming species consist predominantly of C[sub x]N[sub y] (x,y<=2) species. The total number of C-containing ions strongly depends on the N[sub 2] fraction in the discharge and can be increased by almost one order of magnitude scaling with the availability of N[sub 2] as the discharge gas. This finding suggests that besides C and N atoms and ions, other species, like preformed C[sub x]N[sub y] particles, play an important role during growth of fullerene-like (FL) carbon nitride (CN[sub x]) thin films. It is proposed that such clusters have a direct effect as growth templates or nucleation sites on the evolution of curved and cross-linked FL structures. The carbon target was identified as the main source of preformed C-containing species, following from the pressure dependence of the ion energy distributions of the most abundant C[sub x]N[sub y] (x,y<=2) ions. © 2003 American Institute of Physics. [ABSTRACT FROM AUTHOR]
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- 2003
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37. Growth of fullerene-like carbon nitride thin solid films by reactive magnetron sputtering; role of low-energy ion irradiation in determining microstructure and mechanical properties.
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Neidhardt, J., Czigány, Zs., Brunell, I. F., and Hultman, L.
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THIN films , *MAGNETRONS , *SPUTTERING (Physics) , *IONS - Abstract
Fullerene-like (FL) carbon nitride (CN[sub x]) films were deposited on Si (100) substrates by dc reactive, unbalanced, magnetron sputtering in a N[sub 2]/Ar mixture from a high-purity pyrolythic graphite cathode in a dual-magnetron system with coupled magnetic fields. The N[sub 2] fraction in the discharge gas (0%-100%) and substrate bias (-25 V; -40 V) was varied, while the total pressure (0.4 Pa) and substrate temperature (450 °C) was kept constant. The coupled configuration of the magnetrons resulted in a reduced ion flux density, leading to a much lower average energy per incorporated particle, due to a less focused plasma as compared to a single magnetron. This enabled the evolution of a pronounced FL microstructure. The nitrogen concentration in the films saturated rapidly at 14-18 at. %, as determined by elastic recoil analysis, with a minor dependence on the discharge conditions. No correlations were detected between the photoelectron N1 s core level spectra and the different microstructures, as observed by high-resolution electron microscopy. A variety of distinct FL structures were obtained, ranging from structures with elongated and aligned nitrogen-containing graphitic sheets to disordered structures, however, not exclusively linked to the total N concentration in the films. The microstructure evolution has rather to be seen as in equilibrium between the two competing processes of adsorption and desorption of nitrogen-containing species at the substrate. This balance is shifted by the energy and number of arriving species as well as by the substrate temperature. The most exceptional structure, for lower N[sub 2] fractions, consists of well-aligned, multi-layered circular features (nano-onions) with an inner diameter of approximately 0.7 nm and successive shells at a distance of ∼0.35 nm up to a diameter of 5 nm. It is shown that the intrinsic stress formation is closely linked with the evolution and accommodation of the heavily bent... [ABSTRACT FROM AUTHOR]
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- 2003
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38. Ezetimibe added to statin therapy after acute coronary syndromes
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Cannon, Christopher P., Blazing, Michael A., Giugliano, Robert P., Mccagg, Amy, White, Jennifer A., Theroux, Pierre, Darius, Harald, Lewis, Basil S., Ophuis, Ton Oude, Jukema, J. Wouter, De Ferrari, Gaetano M., Ruzyllo, Witold, De Lucca, Paul, Kyungah, Im, Bohula, Erin A., Reist, Craig, Wiviott, Stephen D., Tershakovec, Andrew M., Musliner, Thomas A., Braunwald, Eugene, Califf, Musliner T, Robert M., Tershakovec, A, Gurfinkel, E, Aylward, P, Tonkin, A, Maurer, G, Van de Werf, F, Nicolau, Jc, Theroux, P, Genest, J, Armstrong, P, Corbalan, R, Isaza, D, Spinar, J, Grande, P, Voitk, J, Kesaniemi, A, Bassand, Jp, Farnier, M, Darius, H, Keltai, M, Mathur, A, Mittal, S, Reddy, K, Lewis, B, De Ferrari GM, Ophuis, To, Jukema, J, White, H, Pedersen, T, Britto, F, Ruzyllo, W, Carrageta, M, Duris, T, Dalby, A, Seung, Kb, Lopez-Sendon, J, Dellborg, M, Mach, F, Guneri, S, Parkhomenko, A, Brady, A, Cannon, C, Blazing, M, Ballantyne, C, de Lemos, J, Kleiman, N, Mcguire, Dk, Centeno, E, Casalins, M, Cartasegna, L, Beltrano, Mc, Guerrero, R, Fanuele, M, Berra, F, Egido, J, Colombo, H, Dellatorre, M, Terns, P, Blumberg, E, Reges, P, Azize, G, Ramos, H, Fernandez, R, Carlessi, C, Milesi, R, Schmuck, R, Duronto, E, Procopio, G, Carlevaro, O, Maffeo, H, Beloscar, J, Viso, M, Hominal, M, Castoldi, M, Bluguermann, J, Mauro, D, Macin, S, Cocco, N, Ruiz, N, Ricart, J, Lozada, A, Nani, S, Turri, D, Fernandez, H, Caruso, O, Zarandon, R, Bono, J, Arias, V, Allall, O, Marino, J, Cusimano, S, Schygiel, P, Buzetti, C, Penaloza, N, Berli, M, Worthley, S, Roach, A, Chew, D, Wright, T, Leitch, J, Hicks, E, Rankin, J, Venn-Edmonds, C, Lehman, R, Morrison, H, Shaw, J, Mak, V, Hii, C, Smith, K, Cross, D, Lilwall, L, Nelson, G, Loxton, A, Horowitz, J, Rose, J, Steinwender, C, Leisch, F, Kammler, J, Brussee, H, Zweiker, R, Niederl, E, Weihs, W, Giorgio, G, Lang, I, Drexel, H, Zanolin, D, Hoppe, U, Atzenhofer-Baumgartner, K, Pichler, M, Hainzer, D, Eber, B, Pichler, F, Foeger, B, Wechselberger, T, Mayr, H, Hofer, J, Stockenhuber, F, Warlits, B, Huber, K, Egger, F, Weidinger, F, Ziegler, B, Jirak, P, Metzler, B, Pachinger, O, Wanitschek, M, Auer, J, Grabscheit, G, Podczeck-Schweighofer, A, Priesnitz, T, Frank, H, El Allaf, D, Marechal, P, Roosen, J, Joly, E, Lefebvre, P, Arend, C, Sinnaeve, P, De Velder, L, Hellemans, S, Vanhauwaert, B, Van Dorpe, A, Heyse, A, Vantomme, C, Striekwold, H, Van Den Broeck, D, Lancellotti, P, Schoors, D, Lemoine, I, Taeymans, Y, De Wolf, L, Brike, C, Vercauteren, S, Tahon, S, Vervoort, G, Mestdagh, I, Pirenne, B, Cardinal, F, Lips, S, Dujardin, K, Debrouwer, K, Dhooghe, G, Holvoet, G, van de Borne, P, Renard, M, De Clippel, M, Lesseliers, H, Van Miert, N, Saraiva, J, Vicente, C, Rossi, P, Dos Santos LB, Duda, N, Tognon, Ap, Serrano, C, Gomes, Fl, Manenti, Er, Silveira, Ds, Maia, L, Mouco, Om, Paiva, M, Antonangelo, A, de Souza, J, Lino, Ea, Leães, P, Blacher, Mg, Kormann, A, Ultramari, Ft, Dutra, O, Mendelski, Am, Morgado, S, Ardito, W, Greque, G, Ardito, Rv, Pimentel Filho, P, Zucchetti, C, Alves, A, Seabra, Am, Mattos, M, Miranda, Lf, Silva, D, Uehara, Rm, Marin Neto, J, Schmidt, A, Braga, J, Rodrigues, A, Abrantes, J, Pinheiro, L, Bodanese, L, Magedanz, Éh, Piegas, L, Dos Santos ES, Wainstein, M, Ribeiro, J, Stein, R, Marino, R, Machado, Vm, Moraes Junior, J, Guimarães, S, da Costa FA, Ferraz, Rf, Albuquerque, D, Rocha, Rm, de Carvalho Moreira, R, Dohmann, H, Costantini, C, Tarastchuk, Jc, Coelho, O, Cirillo, W, Sousa, A, Almeira, As, Stefanini, E, Silva, F, Teixeira, M, da Cunha, C, Précoma, D, Facchi, Tl, Rupka, D, Thiessen, S, Warnica, J, Smith, B, Della Siega, A, Klinke, P, Nelson, S, Dion, D, Gilbert, N, Hui, W, Kvill, L, Sussex, B, Luther, A, Dupuis, R, Ouimet, F, Pandey, A, Clarus, S, Senaratne, M, Ferdinandis, H, Mukherjee, A, Bozek, B, Vizel, S, Markov, G, Zimmermann, R, Stephens, W, Tremblay, B, Wong, G, Uchida, N, Brossoit, R, Peck, C, Van Kieu, C, Forgione, M, Bata, I, Cossett, J, Kostuk, W, Arnold, M, Bone, C, Grondin, F, Bilodeau, N, Gosselin, G, David, M, Giannoccaro, J, Beresford, P, Polasek, P, Roberts, P, Doucet, M, Beaudry, M, Cheung, S, Cleveland, T, Bhargava, R, Mccallum, A, Ma, P, Morrissette, J, Cleveland, D, Chadwyn, D, Nigro, F, Weeks, A, Cryderman, C, Leader, R, Houde, G, Rousseau, S, Pearce, M, Radyk, M, Lonn, E, Magi, A, Lefkowitz, C, Sandrin, F, Coffin, N, Lubelsky, B, Coldwell, J, Habot, J, Mcpherson, C, De Larochelliere, R, Roy, M, Haichin, R, Barber, C, Bhesania, T, Kitagawa, H, To, T, Donnelly, B, Tymchak, W, Harris, L, Kouz, S, Huynh, T, St Jacques, B, Lamy, A, Rizzo, A, Stein, J, Childs, C, Wong, B, Poirier, R, Gupta, M, Dela Cruz, C, Constance, C, Gauthier, M, Ervin, F, Ouellette, M, Kokis, A, Lemay, C, Kwok, K, Leung, C, Lee, D, Nesmith, J, Renton, J, Syan, G, Turek, M, Hogan, D, Griffin, P, Lipson, A, Winestock, J, Abramson, B, Fogel, A, Gagne, C, Bergeron, J, Clarke, A, Slipp, S, Darcel, I, Carling-Chambers, L, Kannampuzha, P, Pallie, S, Krekorian, S, Vertes, G, Roth, S, Lai, K, Heath, J, Perez, L, Arriagada, G, Castro, P, Villa, F, Rodríguez, M, Ramos, G, Baraona, F, Núñez, A, García, M, Jofre, C, Silva, P, Lamich, R, Yovaniniz, P, Escobar, E, Dussaubat, A, Segura, E, Ramirez, M, Lapostol, C, Palma, A, Encina, L, Zapata, M, Baeza, N, Varela, P, Pérez, L, Jaramillo, C, Ruiz, S, Sanchez, G, Perdomo, I, Manzur, F, Cohen, Le, Velasquez, J, Arana, C, Alvarez, Y, Triana, M, Balaguera, J, de Salazar, D, Rendon, N, Botero, R, Ruiz, A, Saaibi, J, Medina, J, Jaramillo, M, Calderón, Mj, Delgado, J, Bohorquez, R, Medina, Mf, Herrera, M, Rosales, D, Mendoza, F, Martinez, S, Ternera, A, Castro, R, Baiz, A, Martinez, M, Orozco, A, Suarez, M, Fonseca, Y, Beltran, R, Cepeda, M, Jaramillo, N, Valenzuela, C, Gutierrez, M, Sanchez, A, Vitovec, J, Hlinomaz, O, Poloczek, M, Mayer, O, Veselka, J, Vejvoda, J, Soucek, M, Spac, J, Novobilsky, K, Srp, V, Francek, L, Branny, M, Sknouril, L, Motovska, Z, Rohac, F, Stankova, A, Fiala, T, Holub, M, Zeman, K, Pohludkova, L, Pospisilova, E, Tuma, P, Cihalik, C, Oral, I, Podpera, I, Stepanovova, R, Uricar, M, Solar, M, Pelouch, R, Porzer, M, Grussmannova, K, Stipal, R, Reichert, P, Hradec, J, Kral, J, Sejkova, B, Janek, B, Pitha, J, Linhart, A, Polacek, P, Koeber, L, Clemmensen, P, Hebin, Ch, Schmidt, E, Pedersen, Ms, Roseva-Nielsen, N, Kristensen, K, Bang-Hansen, T, Jensen, J, Laage-Petersen, J, Nielsen, H, Stokholm, E, Thayssen, P, Cappelen, H, Jensen, T, Winther-Friis, B, Klausen, I, Hedegaard, B, May, O, Andersen, M, Bottzauw, J, Lush, A, Markenvard, J, Vestager, Km, Bronnum-Schou, J, Hempel, H, Petersen, J, Nielsen, Aj, Thomsen, K, Nielsen, T, Nygaard, A, Sykulski, R, Jensen, Bs, Ralfkiaer, N, Gottschalck, H, Rasmussen, S, Pedersen, Lr, Dodt, K, Skovsbøl, M, Andersen, O, Tuxen, C, Meier, Aw, Kristensen, T, Rasmussen, O, Lopez, J, Salazar, D, Sanchez, L, Rosero, F, Penaherrera, E, Duarte, Yc, Marmol, R, Andrade, G, Guzman, E, Morillo, A, Aug, L, Loogna, I, Laanmets, P, Mustonen, J, Mäntylä, P, Kesäniemi, A, Ukkola, O, Kervinen, H, Juhela, S, Juvonen, J, Toppinen, A, Jarvenpaa, J, Syvanne, M, Svahn, T, Voutilainen, S, Huotari, A, Nikkila, M, Raiskinmäki, S, 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Sabatine, M., Marti, J., Perlman, R., Pavlides, A., Joffe, I., Albirini, A., Campbell, T., Puri, S., Lopez, C., Pearce, D., Shah, D., McPherson, J., Donegan, R., Murdock, D., Block, D., Malik, A., Musina, R., Dauber, I., Varner, C., Bach, R., Palazzolo, M., Bhalla, H., Thompson, M., Pollock, S., Johnson, S., Lipson, L., Brunk, S., Karas, S., Vicari, R., Kuvin, J., Mooney, P., Aycock, G., Lane, B., Sharma, M., Gibson, T., Chang, G., DiVito, P., Mehta, R., Watkins, K., Chiu, A., Gunderson, J., Tedder, B., Williams, P., Hage-Korban, E., Childs, A., Banerjee, S., Kazi, F., Bennett, J., Barnes, D., Wohns, D., Noorman, C., Aggarwal, K., Lau-Sickman, A., Paulowski, J., Amos, M., Rider, J., Fenton, S., Schantz, M., Hakas, J., Mcsorley, J., Felten, W., Bitzer, V., Russell, J., Loyo, J., Adjei, A., Mehta, K., Uretsky, B., Hale, M., Shaikh, S., Miller, M., Hollenbaugh, D., Crawford, K., Fortuin, D., Galindo, A., Del Core, M., Butkus, E., Collins, J., Prior, J., Hahn, R., Greene-Nashold, J., Alexander, J., Genova, E., MacDonell, A., Broadwater, S., Kereiakes, D., White, D., Lopez, M., Schenks, R., Lui, H., Gibbons, P., Davis, B., Thornton, K., Daley, P., Budzon, S., McCullum, K., Delio-Cox, B., Nadar, V., Keim, S., McLaurin, B., Davis, C., Betzu, R., Al-Jumaily, J., Bolli, R., Alshaher, M., Leesar, M., Collins, T., Akkad, H., Bilazarian, S., Marsters, M., Kennett, J., Melegrito, K., Mostel, E., Harris, R., Chang, M., Hatfield, G., Makam, S., Garvey, M., Levite, H., White, J., Abdel-Latief, A., Pelletier, L., Carr, K., Mckenna, K., De Lemos, J., Soto, G., Kozina, J., Harris, D., Vlastaris, A., Bittel, B., Riba, A., Gugudis, J., Singh, N., Qureshi, I., Doty, W., Lehmann, J., Lieber, I., Martin, S., Nicu, M., Bhalodkar, N., Ravi, P., Canto, J., Bass, M., Campbell, C., Steinhubl, S., Moles, K., Harjai, K., Stapleton, D.D., Hoey, K., Erwin, J., Fikes, W., Stein, B., Sabatino, K., Teklinski, A., Colfer, H., Ward, P., Langevin, E., Faucett, S., Mamdani, S., DeSimone, L., Tuohy, E., Cullen, T., Eisenberg, S., Chronos, N., Allen, R.P., Erickson, B., Mahon, K., Kirby, A., Siegel, C., Stroud, L., Johnson, J., Panchal, V., Pearson, A., Abell, T., De Gregorio, M., Boomer, L., Vahdat, O., VanNatta, B., Long, P., Chalavarya, G., Skatrud, L., Carey, C., Wright, W., Mechem, C., Matthews, B., Adams, A., Vora, K., Wead, J., Koren, M., Gregory, D., El Khadra, M., Peacock, G., Kieval, J., Barron, M., Lewis, D., Grice, R., Bobek, M., Moore, C., Nygaard, T., Fischell, T., Salman, W., Schneider, C., Muhlestein, B., Peeler, D., Chang, D., Todd, A., Chilakamarri, V., Hanley, P., Gelormini, J., Iacona, M.A., Effron, B., Mazzurco, S., Mazzella, M., Wyman, P., Orchard, R., Battin, D., Rezkalla, S., Bishop, C., Sharp, S., Gredler, F., Knap, P., Fadel, M., Saucedo, J., Keng, A., Imburgia, M., Blank, E., Effat, M., Khoury, S., Mardis, R., Baldari, D., Tafuri, L., Mascolo, R., Taylor, D., Mandviwala, M., Khan, W., Mumford, T., Mayer, N., Mitchell, B., Oliver, T., Lombardi, W., Zimmerman, T., Rohrbeck, S., Cooke, L., Craig, M., Mego, D., Griffin, B., Perez, J., LeClerc, K., Addington, J., Aboufakher, R., Ahmed, A., Westecott, B., Steel, K., Hawkins, K., Shah, A., Ward, U., McGreevy, M., Goldberg, R., Prashad, R., McDonough, C., Silver, K., Josephson, R., Witsaman, S., Labib, S., Woodhead, G., Schrank, J., Bell, K., Chandna, H., Holly, D., Bethea, C., Fife, B., Gruberg, L., Singer, A., Ramgadoo, M., Lalonde, T., Morin, R., French, W., Barillas, O., Gradner, G., Kahn, Z., Gress, J., Rocco, D., Thew, S., Stifter, W., Fisher, M., McNamara, J., Kupfer, J., Agocha, A., Cush, S., Jones, S., Whitaker, T., Stover, T., Kumkumian, G., Kent, K., Greenberg, A., Pandey, P., Pytlewski, G., Matsumura, M., Kai, W., Sameshima, S., Thomas, J., MacNicholas, D., Pillai, K., Jones, D., Navas, J.P., Laskoe, B., Patel, P., Fini, G., Minor, S., Shipwash, T., Cabrera-Santamaria, A., Rivera, E., Mincher, L., Jafar, M., Yen, M., Finkle, C., Rahimtoola, A., Severson, L., Labroo, A., Jinich, D., Tam, K., Vogel, C., Aggarwal, R., Zakhary, B., Curtis, S., Lyster, M., Humphrey, K., Lavine, P., Fujise, K., Birnbaum, Y., Allen, J., Kesselbrenner, M., Michel, K., Staniloae, C., Liu, M., Sonel, A., Macioce-Caffas, A., Amidon, T., Leggett, J., Yedinak, S., Gudmundsson, G., Sabharwal, J., Dagefoerde, N., Wu, W., Meyerrose, G., Roongsritong, C., Jenkins, L., Lieberman, S., Sokol, S., Gutierrez, C., Nelson, C., Barrett, J., Hotchkiss, D., Farley, A., Atassi, K., Christy, L., Baig, M., Di Fazio, J., Meengs, M., Thomas, K., Surmitis, J., DeVault, S., Farhat, N., Hulyalkar, A., Riddell, L., Rivera, W., Sheynberg, B., Kobayashi, J., Katsaropoulos, J., Jan, M., Krucoff, M., Paterno, C., Chandrasekaran, S., Curry, R., Cassavar, D., Wheeler, M., McGarvey, J., Schwarz, L., Miller, E., Andrea, B., Carswell, B.S., Lurie, M., Patti, J., Bowden, W., Vasiliauskas, T., Latham, R., Schwartz, B., Bradford, L., Mattleman, S., Wertheimer, J., Goulden, D., Khan, M., Hawkins, B., Ostfeld, R., Mueller, H., Ash, Y., Wilson, V., Bayer, M., Marshall, J., Dobies, D., Dawson, G., Osman, A., Saba, F., Costello, T., Fuentes, F., Underwood, C., Vijay, N., Washam, M., Dietz, W., Glasgow, B., Mukherjee, S., Hinchion, N., Speirs, S., Thornley, A., Lee, K., Movahed, M., Strootman, D., Chernick, R., Parrott, C., Flock, C., Marques, V., Syzmanski, E., Rama, P., Domingo, D., Wu, L., Bauer, B., Dionisopoulos, P., Aggarwal, A., Holcomb, R., Foster, R., Hancock, T., Hargrove, J., Fletcher, A., Stine, R., Bullivant, M., Adams, K., Lohman, J., Klepper, V., Kabour, A., Neidhardt, J., Phillips, W., Tardiff, S., Aji, J., Corut, S., Foster, G., Firek, C., St Goar, F., Sumner, R., Davis, T., Schneider, R., Schneider, W., Villa, A., Desai, V., Chhabra, A., Banks, K., Herzog, W., Burley, T., Quyyumi, A., Smiley, W., Manocha, P., Fishbein, G., Weller, C., Coffman, A., Kim, C., Kedia, A., Firth, B., Rizvi, M., Dahiya, R., Foster, B., Balcells, E., Metzger, D.C., Lester, J., Bissett, J., Fahdi, I., Sides, E.A., Azrin, M., Martin, C., Quick, A., Conaway, D., Garg, M., Schallert, G., Lancaster, L., Mckissick, S., Atieh, M., Garbarino, J., Eisenberg, D., Uusinarkaus, K., Wirtemburg, P., Ellis, J., Cristaldi, J., Berglund, R., Negus, B., Pappas, J., Rocha, R., Nguyen, T., Stone, J., Janosik, D., Labovitz, A., Elmore, N., Dave, R., Loffredo, K., Gabriel, G., Snyder, C., Ahmed, O., Stone, H., Kelley, M., Diffenback, M., Friedman, B., Zirkle, J., Severa, L., Sample, S., Dignen, K., Raisinghani, A., Ben-Yehuda, O., Ghannadian, B., Moscoso, R., Mankowski, J., Boliek, W., Rukavina, M., Davis, W., Ledbetter, S., Handel, F., Mastouri, R., Mahenthiran, J., Foltz, J., Malhotra, V., Jonas, J., Berk, M., Singh, V., Nelson, M., Elsner, G., Gall, J., Kondo, N., Frank, S., Chandraratna, P., Ranasinghe, S., Ebrahimi, R., Treadwell, M., Walters, B., Hughes, L., Kramer, J., Kumar, K., Mente, T., Lachterman, B., Schifferdecker, B., Munshi, K., Sease, D., Waldo, D., Chandler, G., Manns, D., Nahhas, A., Kamalesh, M., Williams, V., Reich, D., Desalca, M., Sharma, S., Liston, M., Gupta, K., Costa, M., Altschuller, A., Lemmertz, K., Shanes, J., Hansen, C., Therrien, M., Mendelson, R., Ramnarine, R., Myers, G., Donovan, C., Klein, M., Fine, D., Owens, S., Murray, C., Ketroser, R., Heifetz, S., Darnell, Z., Touchon, R., Taghizadeh, B., Bohle, D., Norwood, D., Forrest, T., Jackson, S., Shumate, K., Bayles, A., Masroor, M., North, W.K., Fishberg, R., Merveil-Ceneus, B., Butcher, R., Menapace, F., Kilbride, S., Ramabadran, R.S., Loukinen, K., Khalil, J., Ramabadran, R., Walsh, S., Gill, S., Cyncar, R., McLachlan, J., Surakanti, V., Rusterholtz, L., Shoukfeh, F., Stephenson, L., Tsang, M., Nolan, V., Gilchrist, I., Jefferson, D., Feldman, T., Reyes, L., Santos, R., Little, W., Wesley, D., Gharib, W., Mendell, A., Esham, G., Kakavas, P., Whitcomb, C., Book, K., Bazzi, A., Alvarez, J., Cohen, Y., Ayres, T., Rhule, V., Labib, A., Schuler, P., Zughaib, M., Telck, K., Bikkina, M., Turnbull, K., Sharma, T., Orosz, S., Shah, R., Petrino, M., Hughes, M., Hershey, J., Hudock, D., Hui, P., Von Bakonyi, A., Arnold, A., Kappel, D., Pennock, G., Cloud, B., Tucker, K., Harp, L., Hoover, C., Eisenhauer, M., Roth, J., Young, C., Thai, H., Escalante, A., Bautista, J., Gazmuri, R., Nyland, J., Cubeddu, L., DeFranco, A., Dias, D., Fielding, M., Reeves, R., Hermany, P., Meissner-Dengler, S., Evans, M., Flores, E., Tannenbaum, A., McGarr, K., Moran, J., Stout, E., Allred, S., Henderson, D., Crandall, L., Strote, J., Voyles, W., Robeson, D., Bedoya, R., Omar, B., Pettyjohn, F., Revere, C., Coy, K., Margolis, J., Sotolongo, C., Scheffel, M., Munir, A., Shirwany, A., Douglas, L., Girala, R., Humphreys, R., Agarwal, J., Bankowski, D., Watson, R., Bishop, B., Klementowicz, P., Blais, D., Cohen, B., Lobur, E., Dimenna, J., Dempsey, K., Izzo, M., Bondi, L., Carell, E., Eaton, C., Saltiel, F., Grewal, G., Connolly, T., Little, T., Wiegman, P., Gips, S., Held, J., Paraschos, A., Quesada, R., Goudreau, E., Sears, M., Istfan, P., Holt, S., McClung, J., Nguyen, N., Quintana, O., Gottlieb, D., Knutson, T., Barringhaus, K., Lester, F., Sullivan, P., Rodriguez-Ospina, L., Cannon, Cp, Blazing, Ma, Giugliano, Rp, Mccagg, A, White, Ja, Theroux, P, Darius, H, Lewis, B, Ophuis, To, Jukema, Jw, De Ferrari, Gm, Ruzyllo, W, De Lucca, P, Im, K, Bohula, Ea, Reist, C, Wiviott, Sd, Tershakovec, Am, Musliner, Ta, Braunwald, E, Califf, Rm, for the IMPROVE-IT, Investigator, Cianflone, D, Cardiovascular Division (SZG), Brigham and Women's Hospital [Boston], College of Information Science and Engineering, Ritsumeikan University, Montreal Heart Institute (MONTREAL HEART INSTITUTE), Laboratoire des Micro-algues toxiques, Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD)-Institut de Recherche pour le Développement (IRD), Interuniversity Cardiology Institute Netherlands, Institute of Cardiology (WARSAW - Cardiology), Institute of Cardiology, Merck Sharp & Dohme Corp., Merck & Co. Inc, DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE, Facolta' di MEDICINA e CHIRURGIA, AREA MIN. 06 - Scienze mediche, Cannon, C.P., Blazing, M.A., Giugliano, R.P., Mccagg, A., White, J.A., Lewis, B.S., Jukema, J.W., De Lucca, P., Im, K., Bohula, E.A., Reist, C., Wiviott, S.D., Tershakovec, A.M., Musliner, T.A., Braunwald, E., Califf, R.M., for the IMPROVE-IT Investigators [.., C. Rapezzi, ], Other departments, Cannon, Christopher P, Blazing, Michael A., Giugliano, Robert P., Mccagg, Amy, White, Jennifer A., Theroux, Pierre, Darius, Harald, Lewis, Basil S., Ophuis, Ton Oude, Jukema, J. Wouter, De Ferrari, Gaetano M., Ruzyllo, Witold, De Lucca, Paul, Kyungah, Im, Bohula, Erin A., Reist, Craig, Wiviott, Stephen D., Tershakovec, Andrew M., Musliner, Thomas A., Braunwald, Eugene, and Califf, Robert M.
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Male ,Simvastatin ,acute coronary syndrome ,aged ,anticholesteremic agents ,azetidines ,cardiovascular diseases ,cholesterol, ldl ,double-blind method ,drug therapy, combination ,ezetimibe ,female ,humans ,hydroxymethylglutaryl-coa reductase inhibitors ,kaplan-meier estimate ,male ,middle aged ,simvastatin ,triglycerides ,medicine (all ,[SDV]Life Sciences [q-bio] ,Kaplan-Meier Estimate ,030204 cardiovascular system & hematology ,Bococizumab ,Triglyceride ,chemistry.chemical_compound ,0302 clinical medicine ,Azetidine ,Cardiovascular Disease ,Anticholesteremic Agent ,Acute Coronary Syndrome ,Aged ,Anticholesteremic Agents ,Azetidines ,Cardiovascular Diseases ,Cholesterol, LDL ,Double-Blind Method ,Drug Therapy, Combination ,Female ,Humans ,Hydroxymethylglutaryl-CoA Reductase Inhibitors ,Middle Aged ,Triglycerides ,030212 general & internal medicine ,Medicine (all) ,Research Support, Non-U.S. Gov't ,Hazard ratio ,General Medicine ,Acute Coronary Syndrome, Aged ,Anticholesteremic Agents, Azetidines, Cardiovascular Diseases ,Ezetimibe, Female, Humans ,Male, Middle Aged ,3. Good health ,Multicenter Study ,Editorial ,Cholesterol ,Randomized Controlled Trial ,Combination ,Ezetimibe ,lipids (amino acids, peptides, and proteins) ,Human ,medicine.drug ,medicine.medical_specialty ,Acute Coronary Syndroms ,Urology ,Acute Coronary Syndrome/drug therapy ,Anticholesteremic Agents/adverse effects ,Anticholesteremic Agents/therapeutic use ,Azetidines/adverse effects ,Azetidines/therapeutic use ,Cardiovascular Diseases/epidemiology ,Cardiovascular Diseases/mortality ,Cardiovascular Diseases/prevention & control ,Cholesterol, LDL/blood ,Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ,Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ,Simvastatin/therapeutic use ,Triglycerides/blood ,NO ,LDL ,03 medical and health sciences ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Drug Therapy ,Internal medicine ,Journal Article ,medicine ,Comparative Study ,Alirocumab ,business.industry ,PCSK9 ,ta3121 ,Lomitapide ,DOENÇAS CARDIOVASCULARES ,Endocrinology ,chemistry ,Statin Therapy ,Hydroxymethylglutaryl-CoA Reductase Inhibitor ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
BACKGROUND: Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ezetimibe, a nonstatin drug that reduces intestinal cholesterol absorption, can reduce the rate of cardiovascular events further is not known.METHODS: We conducted a double-blind, randomized trial involving 18,144 patients who had been hospitalized for an acute coronary syndrome within the preceding 10 days and had LDL cholesterol levels of 50 to 100 mg per deciliter (1.3 to 2.6 mmol per liter) if they were receiving lipid-lowering therapy or 50 to 125 mg per deciliter (1.3 to 3.2 mmol per liter) if they were not receiving lipid-lowering therapy. The combination of simvastatin (40 mg) and ezetimibe (10 mg) (simvastatin-ezetimibe) was compared with simvastatin (40 mg) and placebo (simvastatin monotherapy). The primary end point was a composite of cardiovascular death, nonfatal myocardial infarction, unstable angina requiring rehospitalization, coronary revascularization (≥30 days after randomization), or nonfatal stroke. The median follow-up was 6 years.RESULTS: The median time-weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in the simvastatin-ezetimibe group, as compared with 69.5 mg per deciliter (1.8 mmol per liter) in the simvastatin-monotherapy group (PCONCLUSIONS: When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit. (Funded by Merck; IMPROVE-IT ClinicalTrials.gov number, NCT00202878.).
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- 2015
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39. Retinal degeneration: Molecular bases, relevance of splicing and therapeutic approaches
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Neidhardt, J, University of Zurich, and Neidhardt, J
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11124 Institute of Medical Molecular Genetics ,570 Life sciences ,biology ,610 Medicine & health - Published
- 2011
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40. Identification of novel mutations in X-linked retinitis pigmentosa families and implications for diagnostic testing
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Neidhardt, J, et al, Glaus, E, Lorenz, B, University of Zurich, and Neidhardt, J
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10018 Ophthalmology Clinic ,11124 Institute of Medical Molecular Genetics ,10039 Institute of Medical Genetics ,570 Life sciences ,biology ,610 Medicine & health ,2731 Ophthalmology - Published
- 2008
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41. Anatomical and functional study on the musculus semimembranosus
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Bejui, J., Walch, G., Gonon, G. P., Carret, J. P., Neidhardt, J. H., and Fischer, L. P.
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- 1984
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42. Growth of carbon-tungsten nanocomposites by high power impulse magnetron sputtering from compound targets
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Yadav, R. K., Abrasonis, G., Munnik, F., Heller, R., Hübner, R., Möller, W., and Neidhardt, J.
- Abstract
High-power impulse magnetron sputtering (HiPIMS, also known as high-power pulsed magnetron sputtering, HPPMS) is a method for physical vapour deposition of thin lms which is based on magnetron sputter deposition. HiPIMS utilises extremely high power densities of the order of kW cm-2 in short pulses (impulses). A distinguishing feature of HiPIMS is its high degree of ionization of the sputtered metal and high rate of molecular gas dissociation. In this poster we present the study on the growth of C-W nanocomposite lms grown in DC (MS) and HiPIMS modes. For deposition, we have used 3 in C and C-W (90 to 10 at%) substrates. In order to prevent arcing, the depositions were carried out with three-pulse sequence followed by a long off-time. Film areal density was determined by Rutherford Backscattering Spectrometry (RBS) and Nuclear Reaction Analysis (NRA). Film microstructure was determined by Raman spectroscopy, X-Ray diraction, and transmission electron microscopy. Film mechanical properties were studied by nanoindentation and scratch test. We got extensive arcing with pure carbon. In contrast, for the compound target we got stable plasma condition with duty cycle as low as 1 %. Deposited films consist of WC nanoparticles embedded in a carbon matrix. From NRA and RBS, the film areal density of tungsten shows a small decrease concomitantly with the duty cycle (transition from pulsed DC to HiPIMS). In contrast, the film areal density of carbon remains constant. This implies that in different sputtering modes like Ar + dominated in the pulsed DC mode or a mixture of Ar/W ions in the HiPIMS mode the average sputtering rate of carbon is not affected. A collisional computer simulation using TRIDYN was carried out to show a considerable sputter yield amplication of carbon when irradiated with a mixture of Ar/W ions. This is in-line with the observed stable carbon film areal density, which can be attributed to the compensation of the change in sputtering ion composition by sputter yield amplication due to W-enrichment of the target surface. Film characterization shows that there is no signicant change between the films grown in DC and HiPIMS modes.
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- 2013
43. Mechanisms of electrical and optical properties modification of ZnO:Al films induced by very rapid thermal processing
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Vinnichenko, M., Hauschild, D., Cornelius, S., Krause, M., Gago, R., Mücklich, A., Neidhardt, J., Lissotschenko, V., and Kolitsch, A.
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high-power diode laser annealing ,transparent conductive oxides ,Al [ZnO] - Abstract
Thermal processing at millisecond range (very rapid thermal processing, vRTP) is an attractive approach of ZnO:Al film properties improvement compared to RTP or time-consuming isothermal annealing. This is of importance for development of cost-efficient transparent electrodes for thin film solar cells. The present study elucidates the effects of thermal processing on the film optical and electrical properties comparing vRTP treatment at ambient atmosphere using a laser source (~1 ms dwell time) with isothermal annealing in vacuum (1 hour, Ta≤550 °C). The films were grown by reactive pulsed magnetron sputtering (MS) at lab scale and non-reactive MS using an industrial in-line system. The optimized laser processing and the isothermal annealing of the films grown at low temperatures (RT-100 °C) result in an increase of their transmittance in the visible, decrease of electrical resistivity from (1-2)x10^-3 to less than 5x10^-4 Ohm cm, substantial increase of free electron mobility, µe, and density, Ne. Laser annealing of the films grown under optimized conditions at 350 °C does not improve their properties, while isothermal annealing leads to an increase of µe values above 50 cm2V-1s-1. According to TEM, ellipsometry, Raman spectroscopy and XANES, annealing of intra-grain oxygen-related point defects during vRTP has a main effect on the film electrical properties, while during isothermal annealing additional improvement of crystallinity needs to be taken into account.
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- 2012
44. Synthesis of SrTiO3 by crystallization of SrO/TiO2 superlattices prepared by atomic layer deposition
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Riedel, Stefan, Neidhardt, J., Jansen, S., Wilde, Lutz, Sundqvist, Jonas, Erben, E., Teichert, S., Michaelis, A., and Publica
- Abstract
An approach for the preparation of homogenous SrTiO3 (STO) thin films with unprecedented compositional control is presented. Nanolaminates of SrO and TiO2 were deposited at 300 °C by atomic layer deposition on bare silicon, as well as on ruthenium electrodes using metalorganic precursors [Ti(NEtMe)4 (TEMATi),Sr(iPr3Cp)2 (AbsoluteSr)]. Care was taken that the individual sublayers were grown with a number of subcycles well in the steady-state growth regime. This enabled linear composition tuning with the Sr:Ti pulse ratio, which is beneficial for process control. Still, a substrate-specific growth behavior was observed for the individual precursors leading to different cycle ratio/composition dependence for samples grown on Si as compared to Ru substrates. This could be attributed to specific nucleation conditions, which are most pronounced for the initial cycle, but also prevail throughout the film. The as-deposited layers are well separated and the sublayers are amorphous. Subsequent furnace-annealing generated polycrystalline cubic STO films, but also caused a severe distortion of the metal electrode/STO stack, due to interdiffusion. The latter was suppressed by optimized rapid thermal crystallization anneals.
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- 2011
45. The molecular basis of human retinal and vitreoretinal diseases
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Berger, W, Kloeckener-Gruissem, B, Neidhardt, J, University of Zurich, and Berger, W
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11124 Institute of Medical Molecular Genetics ,2809 Sensory Systems ,10039 Institute of Medical Genetics ,10076 Center for Integrative Human Physiology ,570 Life sciences ,biology ,610 Medicine & health ,10064 Neuroscience Center Zurich ,2731 Ophthalmology - Published
- 2010
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46. Alterations of the 5'untranslated region of SLC16A12 lead to age-related cataract
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Zuercher, J, Neidhardt, J, Magyar, I, Labs, S, Moore, A T, Tanner, F C, Waseem, N, Schorderet, D F, Munier, F L, Bhattacharya, S, Berger, W, Kloeckener-Gruissem, B, University of Zurich, and Kloeckener-Gruissem, B
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Monocarboxylic Acid Transporters ,Aging ,10039 Institute of Medical Genetics ,Genetic Vectors ,2804 Cellular and Molecular Neuroscience ,610 Medicine & health ,Cataract ,Cell Line ,11124 Institute of Medical Molecular Genetics ,2809 Sensory Systems ,Vascular ,Humans ,Genetic Predisposition to Disease ,Polymorphism ,Aged ,DNA Primers ,Reverse Transcriptase Polymerase Chain Reaction ,Molecular ,Single Nucleotide ,2731 Ophthalmology ,Gene Expression Regulation ,Mutation ,Radial Artery ,570 Life sciences ,biology ,Muscle ,Female ,Smooth ,5' Untranslated Regions ,Cloning ,Plasmids - Published
- 2010
47. Effect of temperature on the retention of 2 keV Cs+ ions in Si
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Wilde, C., Möller, W., and Neidhardt, J.
- Abstract
Introduction: Cesium is a commonly used species for SIMS, because it provides a high negative secondary ion yield. For more quantitative modeling of the secondary ion yield during SIMS the precise knowledge of the amount of Cs retained in the near surface region is vital. Its equilibrium concentration can be theoretically described by the implantation process and the material removal by (self) sputtering. However, the experimentally determined concentrations of Cs ions retained in Si [1] are lower than that predicted by TRIDYN or by the model of Schulz and Wittmaack [2]. This indicates more complex interaction of chemical (compound formation) or physical nature (texture), which is not described by the given models. The chemical incorporation of residual gas is thought to be a possible reason (e. g. [3]). Therefore, an IBA set-up including RBS and ERD for simultaneous in-vacuo detection of Cs and O in Si was developed to analyze the incorporation of oxygen during Cs sputtering as a function of sample temperature in order to draw conclusion of their activation threshold. Results: Fig. 1 shows the saturation of Cs in Si at room temperature. The temporal development is consistent with the model of implantation and self sputter-ing. Regardless the low partial pressure of oxygen, there is also a strong correlation between Cs and O indicating ion induced incorporation pathways on top of the natural oxide on the untreated Si surface. Fig. 2 shows the steady state areal densities for Cs and O as a function of temperature. Two discrete steady state regimes for Cs are observed at high (> 500°C) and low (< 250°C) temperatures with an transition, where the steady state areal density de-creases almost linearly by a factor of four. The O concentration behaves congruently, while the deviation at temperatures > 600°C might be attributed to thermal oxidation. Conclusion: Even though no significant influence on the physical conditions of the sputtering processes are expected within the temperature range, the Cs areal density shows two discrete regimes, which, interestingly, correlate closely to the amount of O incorporated from residual gas even at base pressures below 10-7 mbar. The reported recrystallisation by rapid thermal annealing with an app. 10% increase of sputter yield shown by Anderson [4] for Ar in Ge seems to be much to small to explain this strong de-crease of steady state Cs concentration. Instead overlying chemical processes are thought to play a major role, e. g. the Cs enhanced formation of mixed oxides (e. g. Cs2O shown by Michel et al. [5]) can impact sputtering yields and/or thermally desorb in the ob-served temperature range under UHV conditions. The precise nature remains unclear up to now and follow-up experiments at different O partial pressures might provide further insights. References: [1] Gnaser H. NIMB 267 (2009) 28082816. [2] Schulz F. and Wittmaack K. Ra-diat. Eff. 29 (1976) 31-40. [3] Berghmans B. and Van-dervorst W. J. Appl. Phys. 106 (2009), 033509. [4] Anderson G. S. J. Appl. Phys. 38 (1967) 1607-1611. [5] Michel E. G. et al. Phys. Rev. B 38 (1988) 13999-13406.
- Published
- 2010
48. The nanostructure, wear and corrosion performance of arc-evaporated CrBxNy nanocomposite coatings
- Author
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Polychronopoulou, K., Baker, M. A., Rebholz, Claus, Neidhardt, J., O'Sullivan, M., Reiter, A. E., Kanakis, K., Leyland, A., Matthews, A., Mitterer, C., and Polychronopoulou, K. [0000-0002-0723-9941]
- Subjects
Chromium ,Corrosion tests ,Wear rates ,Hard coatings ,Scanning electron microscope ,X ray photoelectron spectroscopy ,Analytical chemistry ,Optical microscopy ,Nano-composite coating ,Coating growth ,Nanocomposites ,Wear ,Coating ,Phase diagrams ,Coating system ,Materials Chemistry ,Alumina balls ,Chemical analysis ,Atmospheric humidity ,Dry sliding wear test ,Nitrogen fraction ,Cavity resonators ,Raman ,Protective coatings ,Humidity control ,X ray diffraction analysis ,Surfaces and Interfaces ,Condensed Matter Physics ,Relative humidities ,Surfaces, Coatings and Films ,Corrosion ,Wear of materials ,Electric potential ,Corrosion performance ,Raman spectroscopy ,SEM ,symbols ,3.5%Nacl ,Atmospheric corrosion ,Scanning electron microscopy ,Coating compositions ,Elastic recoil detection analysis ,Nanostructure ,Materials science ,Welds ,X ray diffraction ,Sodium chloride ,Chromate coatings ,Wear tracks ,engineering.material ,Structure (composition) ,Time of flight ,symbols.namesake ,X-ray photoelectron spectroscopy ,XPS ,Corrosion behaviour ,Potentiodynamics ,Room temperature ,Nanocomposite ,Passive current densities ,Equilibrium phase diagrams ,General Chemistry ,Nanostructures ,Elastic recoil detection ,engineering ,Nano-composite structure ,Surface compositions ,Optical profilometry - Abstract
The composition, nanostructure, tribological and corrosion behaviour of reactive arc evaporated CrB x N y coatings have been studied and compared to CrN. The CrB x N y coatings were deposited on a commercial Oerlikon Balzers RCS coating system employing 80:20 Cr:B targets. To vary the composition, the nitrogen fraction was adjusted (N 2 fraction = N 2 /(Ar + N 2 )) and a moderate bias voltage of − 20 V was applied during coating growth. The coating composition and nanostructure was determined using time-of-flight elastic recoil detection analysis (TOF-ERDA), x-ray diffraction (XRD) and x-ray photoelectron spectroscopy (XPS). Ball-on-disc dry sliding wear tests were conducted using an alumina ball counterface both at room temperature and at 500 °C with the relative humidity controlled at 20%. Potentiodynamic corrosion tests were undertaken in 3.5% NaCl aqueous solution. The wear tracks were examined using optical profilometry and scanning electron microscopy (SEM); the surface composition inside and outside of the wear tracks were investigated using Raman spectroscopy and XPS. All coatings exhibit nanocomposite structures and phase compositions which are in fair agreement with those expected from the equilibrium phase diagram. The lowest wear rate at room temperature and 500 °C was found for CrB 0.14 N 1.14 , which was shown to exhibit the highest hardness and possesses a nanocomposite nc-CrN/a-BN structure. CrB 0.12 N 0.84 coatings showed the lowest passive current density in potentiodynamic corrosion tests.
- Published
- 2009
49. Overexpression of RPGR leads to male infertility in mice due to defects in flagellar assembly
- Author
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Brunner, S, Colman, D, Travis, A J, Luhmann, U F O, Shi, W, Feil, S, Imsand, C, Nelson, J, Grimm, C, Rülicke, T, Fundele, R, Neidhardt, J, Berger, W, University of Zurich, and Berger, W
- Subjects
10018 Ophthalmology Clinic ,1307 Cell Biology ,11124 Institute of Medical Molecular Genetics ,570 Life sciences ,biology ,610 Medicine & health ,2743 Reproductive Medicine - Published
- 2008
50. Vascular changes in the cerebellum of Norrin /Ndph knockout mice correlate with high expression of Norrin and Frizzled-4
- Author
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Luhmann, U F O, Neidhardt, J, Kloeckener-Gruissem, B, Schäfer, N F, Glaus, E, Feil, S, Berger, W, University of Zurich, and Berger, W
- Subjects
11124 Institute of Medical Molecular Genetics ,10039 Institute of Medical Genetics ,570 Life sciences ,biology ,2800 General Neuroscience ,610 Medicine & health - Published
- 2008
- Full Text
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