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24 results on '"Nuclear targets"'

1. Ammonia borane-based targets for new developments in laser-driven proton boron fusion.

Author

Picciotto, Antonino, Valt, Matteo, Molloy, Daniel P., Gaiardo, Andrea, Milani, Alessandro, Kantarelou, Vasiliki, Giuffrida, Lorenzo, Nersisyan, Gagik, McNamee, Aaron, Kennedy, Jonathan P., Fitzpatrick, Colm R.J., Martin, Philip, Orecchia, Davide, Maffini, Alessandro, Scauso, Pietro, Vanzetti, Lia, Turcu, Ion Cristian Edmond, Ferrario, Lorenza, Hall-Wilton, Richard, and Margarone, Daniele

Subjects
*NUCLEAR fusion, *NUCLEAR reactions, *CONTROLLED fusion, *RADIOBIOLOGY, *LASER pulses, *ALPHA rays
Abstract

[Display omitted] • Ammonia borane as an innovative material proton-boron fusion. • Extensive characterization of targets using morphological and chemical techniques. • Practical and facile synthesis and industrial viability. Nuclear fusion reactions involving protons and boron-11 nuclei are sparking increasing interest thanks to advancements in high-intensity, short-pulse laser technology. This type of reaction holds potential for a wide array of applications, from controlled nuclear fusion to radiobiology and cancer therapy. In line with this motivation, solid ammonia borane samples were developed as target material for proton-boron (pB) nuclear fusion. Following synthesis and shaping, these samples were tested for the first time in a laser-plasma pB fusion experiment. An investigation campaign focusing on surface chemical/physical analysis was carried out to characterize such samples in terms of composition of B and H, precursors of the pB fusion nuclear reaction, thus having a key impact on the yield of the generated nuclear products, i.e., alpha particles. A follow-up experiment used an 8 J, 800 fs laser pulse with an intensity of 2 × 1019 W cm−2 to irradiate the targets, generating ∼ 108 alpha particles per steradian. The alpha particle energy range (2–6 MeV) and normalized yield per laser energy of up to (6 × 107 J/sr) are comparable with the best previous alpha particle yields found in literature. These results pave the way for a yet unexplored category of pB fusion targets. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Molecular determinants as therapeutic targets in cancer chemotherapy: An update.

Author

Haider, Tanweer, Tiwari, Rahul, Vyas, Suresh Prasad, and Soni, Vandana

Subjects
*ORGANELLES, *CANCER chemotherapy, *TARGETED drug delivery, *CYTOCHROME c, *ENDOPLASMIC reticulum, *METABOLIC profile tests
Abstract

It is well known that cancer cells are heterogeneous in nature and very distinct from their normal counterparts. Commonly these cancer cells possess different and complementary metabolic profile, microenvironment and adopting behaviors to generate more ATPs to fulfill the requirement of high energy that is further utilized in the production of proteins and other essentials required for cell survival, growth, and proliferation. These differences create many challenges in cancer treatments. On the contrary, such situations of metabolic differences between cancer and normal cells may be expected a promising strategy for treatment purpose. In this article, we focus on the molecular determinants of oncogene-specific sub-organelles such as potential metabolites of mitochondria (reactive oxygen species, apoptotic proteins, cytochrome c, caspase 9, caspase 3, etc.), endoplasmic reticulum (unfolded protein response, PKR-like ER kinase, C/EBP homologous protein, etc.), nucleus (nucleolar phosphoprotein, nuclear pore complex, nuclear localization signal), lysosome (microenvironment, etc.) and plasma membrane phospholipids, etc. that might be exploited for the targeted delivery of anti-cancer drugs for therapeutic benefits. This review will help to understand the various targets of subcellular organelles at molecular levels. In the future, this molecular level understanding may be combined with the genomic profile of cancer for the development of the molecularly guided or personalized therapeutics for complete eradication of cancer. Unlabelled Image [ABSTRACT FROM AUTHOR]

Published
2019
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3. Blister resistant targets for nuclear reaction experiments with [formula omitted]-particle beams.

Author

Hunt, Sean, Hunt, Camden, Iliadis, Christian, and Falvo, Michael

Subjects
*NUCLEAR reactions, *PARTICLE beams, *FUSED silica, *NOBLE gases, *POROSITY
Abstract

Abstract Solid targets for nuclear measurements that use α -particle beams commonly experience a form of degradation known as blistering. The effect can prevent the use of solid targets for high intensity α -particle experiments, often necessitating complex gas target systems. To combat this problem, three different blister resistant target backings were designed for use in direct reaction measurements with high intensity α -particle beams. The blister resistant target designs utilize gas diffusive properties of fused silica, sintered metal, and porous evaporated metal. Each target was implanted with 22Ne ions and bombarded with α -particle beam to test blister resistance. Targets were characterized and monitored using the 22Ne(p , γ)23Na reaction to determine the degradation of implanted material, and compare them to typical implanted noble gas targets. We find that all targets studied exhibit resistance to blistering, with the porous evaporated metal targets displaying the least amount of target material degradation. [ABSTRACT FROM AUTHOR]

Published
2019
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4. Uranium Carbide Fibers with Nano-Grains as Starting Materials for ISOL Targets

Author

Sanjib Chowdhury, Leonor Maria, Adelaide Cruz, Dario Manara, Olivier Dieste-Blanco, Thierry Stora, and António Pereira Gonçalves

Subjects
nuclear targets, uranium carbides, nano-scale, electrospinning, fibers, Chemistry, QD1-999
Abstract

This paper presents an experimental study about the preparation, by electrospinning, of uranium carbide fibers with nanometric grain size. Viscous solutions of cellulose acetate and uranyl salts (acetate, acetylacetonate, and formate) on acetic acid and 2,4-pentanedione, adjusted to three different polymer concentrations, 10, 12.5, and 15 weight %, were used for electrospinning. Good quality precursor fibers were obtained from solutions with a 15% cellulose acetate concentration, the best ones being produced from the uranyl acetate solution. As-spun precursor fibers were then decomposed by slow heating until 823 K under argon, resulting in a mixture of nano-grained UO2 and C fibers. A last carboreduction was then carried out under vacuum at 2073 K for 2 h. The final material displayed UC2−y as the major phase, with grain sizes in the 4 nm–10 nm range. UO2+x was still present in moderate concentrations (~30 vol.%). This is due to uncomplete carboreduction that can be explained by the fiber morphology, limiting the effective contact between C and UO2 grains.

Published
2020
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5. Heavy-ion beam induced effects in enriched gadolinium target films prepared by molecular plating.

Author

Mayorov, D.A., Tereshatov, E.E., Werke, T.A., Frey, M.M., and IIIFolden, C.M.

Subjects
*GADOLINIUM, *ELECTROPLATING, *ION beams, *MONOMOLECULAR films, *X-ray diffraction
Abstract

A series of enriched gadolinium (Gd, Z = 64) targets was prepared using the molecular plating process for nuclear physics experiments at the Cyclotron Institute at Texas A&M University. After irradiation with 48 Ca and 45 Sc projectiles at center-of-target energies of E cot = 3.8–4.7 MeV/u, the molecular films displayed visible discoloration. The morphology of the films was examined and compared to the intact target surface. The thin films underwent a heavy-ion beam-induced density change as identified by scanning electron microscopy and α-particle energy loss measurements. The films became thinner and more homogenous, with the transformation occurring early on in the irradiation. This transformation is best described as a crystalline-to-amorphous phase transition induced by atomic displacement and destruction of structural order of the original film. The chemical composition of the thin films was surveyed using energy dispersive spectroscopy and X-ray diffraction, with the results confirming the complex chemistry of the molecular films previously noted in other publications. [ABSTRACT FROM AUTHOR]

Published
2017
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6. THE MOTT POLARIMETER AT MAMI.

Author

Tioukine, V., Aulenbacher, K., and Riehn, E.

Subjects
POLARIZED electrons, POLARIMETRY, ELECTRON accelerators, POLARIZATION (Nuclear physics), MONTE Carlo method
Published
2011

7. Fabrication and characterization of thin [formula omitted]Gd targets for nuclear fusion reaction studies.

Author

Prajapat, Rinku, Maiti, Moumita, S.R., Abhilash, Umapathy, G.R., Kabiraj, D., Khan, S.A., Khandelwal, Deeksha, and Dawar, Anit

Subjects
*HEAVY ion fusion reactions, *PHYSICAL vapor deposition, *ENERGY dispersive X-ray spectroscopy, *ELECTRON microscope techniques, *MELTING points
Abstract

Thin isotopically enriched 156 , 158 Gd target foils of thickness between ≈ 100– 150 μ g /cm2 have been fabricated. The target foils were prepared on carbon backing to provide extra support using the physical vapor deposition (PVD) technique. The fabricated target foils have been used to study the dynamics of heavy-ion induced fusion reactions using the Heavy Ion Reaction Analyser (HIRA) facility at IUAC New-Delhi, India. Due to the high melting point, the e-gun method was adopted to deposition carbon and gadolinium. During fabrication, the challenges were (i) minimal isotopic material, (ii) selection of the parting agent, and (iii) the floating process for separating the gadolinium film from the glass slides. In view of this, the first several attempts have been made with natural gadolinium oxide material to optimize specific parameters. Finally, using only ≈ 38 mg isotopically enriched material for each isotope, eight 156Gd and twenty 158Gd targets were prepared successfully. The nobleness of this work is that the gadolinium material was in oxide form, which provides extra stability to the fabricated targets even in the atmospheric environment. Further, various characterization techniques such as Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectroscopy (EDS), X-ray Diffractometry (XRD), and Rutherford Back-scattering Spectroscopy (RBS), have been explored to investigate surface morphology, elemental purity, chemical composition, and thickness of the target foils. The characterizations and analysis of experimental data manifested that no such impurities were present in the fabricated target foils. Essentially, it has been observed that the fabricated thin 156 , 158 Gd target foils survived against the heavy-ion ( 28 , 30 Si) irradiation throughout the online fusion experiment. • Fabrication of thin isotopically enriched 156,158Gd foils. • 156,158Gd target preparation for nuclear reaction studies. • Physical vapor deposition of gadolinium oxides. • Characterization of fabricated 156,158Gd foils. [ABSTRACT FROM AUTHOR]

Published
2022
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8. Preparation and characterization of isotopically pure Mo targets for nuclear science measurements.

Author

Kelmar, R., Manukyan, K.V., Simon, A., and Aprahamian, A.

Subjects
*NUCLEAR science, *MOLYBDENUM, *GOLD, *FOCUSED ion beams, *X-ray emission spectroscopy, *SCANNING electron microscopes, *X-ray fluorescence, *ROLLING (Metalwork)
Abstract

Isotopically pure molybdenum targets are essential in various nuclear science measurements. For studies of cross sections of capture reactions on molybdenum, uniform targets with areal densities of hundreds of μ g/cm 2 are desired. Mechanical rolling of enriched metal pieces or vacuum sputtering methods used in previous studies to prepare molybdenum targets are challenging and involve labor- and time-intensive processes. Therefore, reliable and straightforward methods to produce molybdenum targets are crucial. We have developed a new double-step method to produce targets meeting these needs. The first step consists of evaporating isotopically enriched MoO 3 onto gold backings. The second step involves the reduction of the oxide layer in a 5% H 2 -Ar environment to obtain molybdenum targets. X-ray fluorescence (XRF) spectroscopy, X-ray Diffraction (XRD), a scanning electron microscope/focused ion beam milling, and energy-dispersive X-ray spectroscopy (EDS) were used to characterize the targets. These methods show that the targets exhibit a uniform coverage of Mo over the gold backings. However, significant volume shrinkage occurring during the reduction of MoO 3 creates a porous Mo layer where the gold diffuses due to the high processing temperatures, resulting in mixed Mo–Au layers. • Isotopically pure Mo targets were prepared on gold backings. • Target preparation include vacuum evaporation and hydrogen reduction steps. • The characteristics of targets were investigated by XRD, XRF, SEM/FIB/EDS methods. [ABSTRACT FROM AUTHOR]

Published
2022
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9. Promising targets and current clinical trials in metastatic non-squamous NSCLC.

Author

Zer, Alona and Leighl, Natasha

Subjects
CANCER treatment, NON-small-cell lung carcinoma, EPIDERMAL growth factor receptors, ANAPLASTIC lymphoma kinase, ADENOCARCINOMA, ADP-ribosyltransferases, HEAT shock proteins
Abstract

Lung adenocarcinoma is the most common subtype of lung cancer today.With the discovery of epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) rearrangements, and effective targeted therapy, personalized medicine has become a reality for patients with lung adenocarcinoma. Here, we review potential additional targets and novel therapies of interest in lung adenocarcinoma including targets within the cell surface (receptor tyrosine kinases EGFR, human epidermal growth factor receptor 2, RET, ROS1, mesenchymal-epidermal transition, TRK), targets in intracellular signal transduction (ALK, RAS-RAF-MEK, PI3K-AKT-PTEN, WNT), nuclear targets such as poly-ADP ribose polymerase, heat shock protein 90, and histone deacetylase, and selected pathways in the tumor environment. With the evolving ability to identify specific molecular aberrations in patient tumors in routine practice, our ability to further personalize therapy in lung adenocarcinoma is rapidly expanding. [ABSTRACT FROM AUTHOR]

Published
2014
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10. Turbulent liquid metal flow in rectangular shaped contraction nozzles for target applications.

Author

Gordeev, S., Stoppel, L., and Stieglitz, R.

Subjects
*LIQUID metals, *JETS (Fluid dynamics), *TARGETING (Nuclear strategy), *TURBULENCE, *ATMOSPHERIC boundary layer, *SYNCHROTRONS
Abstract

Owing to the high beam power densities envisaged in advanced nuclear targets, liquid metal-operated free surface targets are conceived as one feasible option. There, the free surface is formed by an adequately shaped upstream located nozzle. Target boundary conditions necessitate a detailed knowledge on the turbulent flow in contraction nozzles in order to identify turbulence models accurately predicting experimental findings within the velocity range of interest for nuclear target and hence can then act as design optimisation tools. In this context, a combined experimental and numerical study is conducted on the basis of the turbulent flow in the contraction nozzle of the Super-FRS target. Two aspects determining the turbulent flow in the nozzle have been investigated. The first is a potential relaminarisation of the boundary layer caused by the acceleration within the contraction and the second is a development of the secondary flows due to the pressure gradient in the rectangular shaped ducts cross-section. Regarding the three different turbulence models investigated here only the V2F model exhibited the capability to predict the relaminarisation of the turbulent boundary layer both qualitatively and quantitatively. All turbulence models are able to predict the development of secondary flows induced by pressure gradients in transverse direction with an acceptable accuracy. [ABSTRACT FROM AUTHOR]

Published
2009
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11. Fabrication and characterization of thin 64Zn and 68Zn targets for nuclear reaction measurements.

Author

Noor, Shoaib, S.R., Abhilash, Kabiraj, D., Anjali, and Kalkal, Sunil

Subjects
*ION bombardment, *VAPOR-plating, *NUCLEAR reactions, *THIN films, *VAPOR pressure, *SCANNING electron microscopes, *X-ray fluorescence, *ENERGY dissipation
Abstract

Isotopically enriched targets of 64,68Zn were prepared for heavy ion fusion and multi-nucleon transfer reactions. In view of the fragility of the targets under the ion current and during characterization, multiple targets of each isotope were required. Thin films of 64,68Zn isotopes were fabricated via vapor deposition in the target laboratory at Inter-University Accelerator Center (IUAC), New Delhi. Multiple targets of 64,68Zn in the thickness range 150 μ g/cm2–300 μ g/cm2, were synthesized on a carbon backing of 10 μ g/cm2 using only 30 mg amount of available enriched material for each isotope. The use of a pin source and carbon foils as substrate allowed the fabrication of Zn targets without employing previously suggested methods of substrate cooling and forced condensation for thin film fabrication of volatile elements. The deposition results have been estimated quantitatively. The thickness measurement of the targets was carried out using the α particle energy loss technique and Rutherford Back Scattering (RBS) method. The elemental composition of the targets was examined using RBS and Dispersive Wavelength X-ray Fluorescence (DWXRF) to investigate the contamination. Morphological analysis of the films was performed using Scanning Electron Microscope (SEM) to study homogeneity and the impact of ion bombardment on the targets. • Thin film fabrication of Zn is difficult due to its low vapor pressure. • Use of a pin source provides needful vapor pressure for condensation of Zn vapors. • Use of carbon foils as substrate provides consistent deposition of Zn vapors. • Effect of ion irradiation on thin film is highlighted. [ABSTRACT FROM AUTHOR]

Published
2021
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12. Uranium Carbide Fibers with Nano-Grains as Starting Materials for ISOL Targets.

Author

Chowdhury, Sanjib, Maria, Leonor, Cruz, Adelaide, Manara, Dario, Dieste-Blanco, Olivier, Stora, Thierry, and Gonçalves, António Pereira

Subjects
*CELLULOSE acetate, *URANIUM, *FIBERS, *CARBIDES, *ACETIC acid, *GRAIN size
Abstract

This paper presents an experimental study about the preparation, by electrospinning, of uranium carbide fibers with nanometric grain size. Viscous solutions of cellulose acetate and uranyl salts (acetate, acetylacetonate, and formate) on acetic acid and 2,4-pentanedione, adjusted to three different polymer concentrations, 10, 12.5, and 15 weight %, were used for electrospinning. Good quality precursor fibers were obtained from solutions with a 15% cellulose acetate concentration, the best ones being produced from the uranyl acetate solution. As-spun precursor fibers were then decomposed by slow heating until 823 K under argon, resulting in a mixture of nano-grained UO2 and C fibers. A last carboreduction was then carried out under vacuum at 2073 K for 2 h. The final material displayed UC2−y as the major phase, with grain sizes in the 4 nm–10 nm range. UO2+x was still present in moderate concentrations (~30 vol.%). This is due to uncomplete carboreduction that can be explained by the fiber morphology, limiting the effective contact between C and UO2 grains. [ABSTRACT FROM AUTHOR]

Published
2020
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13. Measurement of the $\nu_{\mu}$ charged current quasi-elastic cross-section on carbon with the T2K on-axis neutrino beam

Author

Y. Nishimura, P. A. Rodrigues, C. A. Miller, E. Rondio, N. McCauley, A. Minamino, Joshua Hignight, Yoshihiro Suzuki, P. de Perio, Yoshikazu Yamada, K. Huang, T. Maruyama, P. Przewlocki, J. Caravaca Rodríguez, H.A. Tanaka, D. Brailsford, O. Drapier, M. Malek, A. Blondel, J. H. Jo, R. Poutissou, C. W. Walter, Anatoly Kopylov, Lester D.R. Thompson, P. Bartet-Friburg, A. Cervera, B. E. Berger, Masashi Tanaka, C. Nantais, V. Palladino, G.D. Barr, M. Kabirnezhad, K. Nishikawa, J. Holeczek, Jan T. Sobczyk, A. P. Furmanski, B. Quilain, M. Yu, T. Ovsyannikova, C. Pistillo, K. Nakayoshi, C. K. Jung, S. Berkman, S. Martynenko, Takaaki Kajita, J. Lagoda, T. Tomura, S. Murphy, J. M. Poutissou, C. Bronner, B. Smith, E. Reinherz-Aronis, R. L. Helmer, R. J. Wilson, A. Redij, Y. Shustrov, V. Paolone, K. Wakamatsu, Hiroyuki Sekiya, A. Jacob, L. Zambelli, I. Karpikov, S. King, B. Still, K. Iyogi, S. Bolognesi, M. R. Vagins, K. Iwamoto, P. Martins, E. Scantamburlo, P. Stamoulis, F. Sato, R. Castillo, Yuichi Oyama, Y. Fukuda, Kendall Mahn, M. Nirkko, R. P. Litchfield, M. Ravonel, A. Rychter, W. R. Kropp, O. V. Mineev, Masato Shiozawa, R.P. Kurjata, P. Rojas, M. Mezzetto, M. Ieva, Akitaka Ariga, Ko Okumura, E. D. Zimmerman, R. Shah, W. Warzycha, Shigeki Aoki, L. Pickard, S. Giffin, S. Assylbekov, Koji Yamamoto, J. P. Lopez, F. Hosomi, Susumu Takahashi, S. Tobayama, A. Zalewska, Federico Sanchez, Y. Takeuchi, I. Z. Danko, M. B. Smy, K. Abe, A. Murakami, Yu. Kudenko, V. Matveev, K. Nakamura, Takahiro Hiraki, M. A.M. Rayner, T. Wongjirad, S. Manly, G. De Rosa, Leïla Haegel, R. A. Owen, A. K. Ichikawa, S. Roth, J. Kameda, S. A. Dytman, K. Sakashita, A. Haesler, R. Tacik, O. Perevozchikov, D. Payne, S. J. Coleman, Antonin Vacheret, V. Galymov, M. Ikeda, S. Bhadra, S. M. Oser, T. Hayashino, C. Hearty, D. R. Hadley, M. M. Khabibullin, E. S. Pinzon Guerra, S. B. Boyd, Th. A. Mueller, A. Garcia, M. Miura, R. Ohta, Stefan Schoppmann, G. Christodoulou, M. Ziembicki, Matthew T. Reeves, M. Barbi, M. Tzanov, P. Mijakowski, J. Zalipska, J. Insler, T. Yuan, T. Sekiguchi, D. Ruterbories, S. Horikawa, C. J. Metelko, T. Ishii, Y. Seiya, T. Wachala, L. Ludovici, André Rubbia, S. Bordoni, C. Touramanis, R. Terri, E. Mazzucato, M. Jiang, S. Moriyama, M. Zito, T. J. Irvine, F. Bay, A. Hillairet, Hiroaki Aihara, H. M. O'Keeffe, S. R. Johnson, Antonio Ereditato, N. Yershov, P. N. Ratoff, Hidekazu Kakuno, M. Sorel, T. Kutter, R. A. Wendell, Masayuki Nakahata, M. McCarthy, A. Thorley, Y. Uchida, C. Riccio, S. L. Cartwright, A. Korzenev, Kevin Scott McFarland, Vincenzo Berardi, Kazuhiro Suzuki, C. Ferchichi, E. Larkin, T. Feusels, A. Longhin, M. Friend, K. Connolly, G. A. Fiorentini, S. Short, H. K. Tanaka, N. C. Hastings, P. Plonski, J. Marteau, Z. Williamson, Teppei Katori, L. L. Kormos, A. Clifton, M. J. Wilking, P. Kitching, K. Mavrokoridis, F. d. M. Blaszczyk, Michal Dziewiecki, M. G. Catanesi, K. Gilje, Alexander Finch, D. Shaw, T. Hasegawa, M. Lawe, Rhiju Das, H. W. Sobel, Y. Kanazawa, A. Konaka, L. Southwell, J. Myslik, Jan Kisiel, T. Dealtry, A. Missert, Artur F. Izmaylov, M. O. Wascko, D. Terhorst, J. D. Perkin, W. H. Toki, B. Jamieson, E. Kearns, T. Tsukamoto, D. Goeldi, T. Kobayashi, S. Di Luise, Yusuke Koshio, M. D. Haigh, L. Cremonesi, K. G. Nakamura, J. Steinmann, T. Golan, I. Lamont, Masashi Yokoyama, F. Di Lodovico, A. T. Suzuki, M. Murdoch, M. Tada, G. Vasseur, E. Poplawska, S. Nakayama, S. Yen, T. Yano, Marco Laveder, Hidetoshi Kubo, Kentaroh Yoshida, A. C. Weber, J. F. Martin, Yuki Fujii, D. Autiero, T. Nakadaira, P. Hamilton, J. Żmuda, K. Zaremba, Seiko Hirota, T. Ishida, T. Kikawa, D. Kielczewska, M. Batkiewicz, Yusuke Suda, L. Magaletti, C. Giganti, M. Gonin, L. Escudero, A. Dabrowska, J. A. Nowak, A. Kolaceke, E. Iwai, Atsushi Takeda, J. Dumarchez, K. E. Duffy, J. Schwehr, C. Yanagisawa, W. Oryszczak, J. Adam, A. Mefodiev, J. Yoo, N. Chikuma, D. Cherdack, J. Imber, R. Sacco, A. N. Khotjantsev, S. Dolan, T. Lindner, S. Emery-Schrenk, Scott Davis, D. Hansen, C. Densham, M. Posiadala-Zezula, N. Grant, J. L. Palomino, G. Collazuol, Mark Scott, Tsuyoshi Nakaya, Gareth J. Barker, M. Hierholzer, Y. Petrov, J. P. Coleman, A. Himmel, A. Kilinski, F. Shaker, B. A. Popov, R. G. Calland, D. Gudin, M. Lazos, N. J. Buchanan, Y. Totsuka, T. Okusawa, K. Ieki, Jungsang Kim, D. Karlen, S. Y. Suzuki, Kate Scholberg, R. J. Wilkes, M. Bass, A. C. Kaboth, M. Hartz, D. Dewhurst, C. Wilkinson, D. Sgalaberna, J. R. Wilson, C. Nielsen, C. Lister, T. Koga, E. Radicioni, D. L. Wark, C. McGrew, T. Hara, L. Koch, A. D. Marino, Y. Hayato, C. Andreopoulos, S. R. Dennis, A. Bravar, P. Jonsson, P. Sinclair, Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), T2K, Ministerio de Economía y Competitividad (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Natural Sciences and Engineering Research Council of Canada, Centre National de la Recherche Scientifique (France), Royal Society (UK), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Abe, K., Adam, J., Aihara, H., Andreopoulos, C., Aoki, S., Ariga, A., Assylbekov, S., Autiero, D., Barbi, M., Barker, G. . j., Barr, G., Bartet Friburg, P., Bass, M., Batkiewicz, M., Bay, F., Berardi, V., Berger, B. . e., Berkman, S., Bhadra, S., Blaszczyk, F. . d. . m., Blondel, A., Bolognesi, S., Bordoni, S., Boyd, S. . b., Brailsford, D., Bravar, A., Bronner, C., Buchanan, N., Calland, R. . g., Caravaca Rodríguez, J., Cartwright, S. . l., Castillo, R., Catanesi, M. . g., Cervera, A., Cherdack, D., Chikuma, N., Christodoulou, G., Clifton, A., Coleman, J., Coleman, S. . j., Collazuol, G., Connolly, K., Cremonesi, L., Dabrowska, A., Danko, I., Das, R., Davis, S., de Perio, P., DE ROSA, Gianfranca, Dealtry, T., Dennis, S. . r., Densham, C., Dewhurst, D., Di Lodovico, F., Di Luise, S., Dolan, S., Drapier, O., Duffy, K., Dumarchez, J., Dytman, S., Dziewiecki, M., Emery Schrenk, S., Ereditato, A., Escudero, L., Ferchichi, C., Feusels, T., Finch, A. . j., Fiorentini, G. . a., Friend, M., Fujii, Y., Fukuda, Y., Furmanski, A. . p., Galymov, V., Garcia, A., Giffin, S., Giganti, C., Gilje, K., Goeldi, D., Golan, T., Gonin, M., Grant, N., Gudin, D., Hadley, D. . r., Haegel, L., Haesler, A., Haigh, M. . d., Hamilton, P., Hansen, D., Hara, T., Hartz, M., Hasegawa, T., Hastings, N. . c., Hayashino, T., Hayato, Y., Hearty, C., Helmer, R. . l., Hierholzer, M., Hignight, J., Hillairet, A., Himmel, A., Hiraki, T., Hirota, S., Holeczek, J., Horikawa, S., Hosomi, F., Huang, K., Ichikawa, A. . k., Ieki, K., Ieva, M., Ikeda, M., Imber, J., Insler, J., Irvine, T. . j., Ishida, T., Ishii, T., Iwai, E., Iwamoto, K., Iyogi, K., Izmaylov, A., Jacob, A., Jamieson, B., Jiang, M., Johnson, S., Jo, J. . h., Jonsson, P., Jung, C. . k., Kabirnezhad, M., Kaboth, A. . c., Kajita, T., Kakuno, H., Kameda, J., Kanazawa, Y., Karlen, D., Karpikov, I., Katori, T., Kearns, E., Khabibullin, M., Khotjantsev, A., Kielczewska, D., Kikawa, T., Kilinski, A., Kim, J., King, S., Kisiel, J., Kitching, P., Kobayashi, T., Koch, L., Koga, T., Kolaceke, A., Konaka, A., Kopylov, A., Kormos, L. . l., Korzenev, A., Koshio, Y., Kropp, W., Kubo, H., Kudenko, Y., Kurjata, R., Kutter, T., Lagoda, J., Lamont, I., Larkin, E., Laveder, M., Lawe, M., Lazos, M., Lindner, T., Lister, C., Litchfield, R. . p., Longhin, A., Lopez, J. . p., Ludovici, L., Magaletti, L., Mahn, K., Malek, M., Manly, S., Marino, A. . d., Marteau, J., Martin, J. . f., Martins, P., Martynenko, S., Maruyama, T., Matveev, V., Mavrokoridis, K., Mazzucato, E., Mccarthy, M., Mccauley, N., Mcfarland, K. . s., Mcgrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Mijakowski, P., Miller, C. . a., Minamino, A., Mineev, O., Missert, A., Miura, M., Moriyama, S., Mueller, T. h. . a., Murakami, A., Murdoch, M., Murphy, S., Myslik, J., Nakadaira, T., Nakahata, M., Nakamura, K. . g., Nakamura, K., Nakayama, S., Nakaya, T., Nakayoshi, K., Nantais, C., Nielsen, C., Nirkko, M., Nishikawa, K., Nishimura, Y., Nowak, J., O’Keeffe, H. . m., Ohta, R., Okumura, K., Okusawa, T., Oryszczak, W., Oser, S. . m., Ovsyannikova, T., Owen, R. . a., Oyama, Y., Palladino, Vittorio, Palomino, J. . l., Paolone, V., Payne, D., Perevozchikov, O., Perkin, J. . d., Petrov, Y., Pickard, L., Pinzon Guerra, E. . s., Pistillo, C., Plonski, P., Poplawska, E., Popov, B., Posiadala Zezula, M., Poutissou, J. M., Poutissou, R., Przewlocki, P., Quilain, B., Radicioni, E., Ratoff, P. . n., Ravonel, M., Rayner, M. . a. . m., Redij, A., Reeves, M., Reinherz Aronis, E., Riccio, Ciro, Rodrigues, P. . a., Rojas, P., Rondio, E., Roth, S., Rubbia, A., Ruterbories, D., Rychter, A., Sacco, R., Sakashita, K., Sánchez, F., Sato, F., Scantamburlo, E., Scholberg, K., Schoppmann, S., Schwehr, J., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shah, R., Shaker, F., Shaw, D., Shiozawa, M., Short, S., Shustrov, Y., Sinclair, P., Smith, B., Smy, M., Sobczyk, J. . t., Sobel, H., Sorel, M., Southwell, L., Stamoulis, P., Steinmann, J., Still, B., Suda, Y., Suzuki, A., Suzuki, K., Suzuki, S. . y., Suzuki, Y., Tacik, R., Tada, M., Takahashi, S., Takeda, A., Takeuchi, Y., Tanaka, H. . k., Tanaka, H. . a., Tanaka, M. . m., Terhorst, D., Terri, R., Thompson, L. . f., Thorley, A., Tobayama, S., Toki, W., Tomura, T., Totsuka, Y., Touramanis, C., Tsukamoto, T., Tzanov, M., Uchida, Y., Vacheret, A., Vagins, M., Vasseur, G., Wachala, T., Wakamatsu, K., Walter, C. . w., Wark, D., Warzycha, W., Wascko, M. . o., Weber, A., Wendell, R., Wilkes, R. . j., Wilking, M. . j., Wilkinson, C., Williamson, Z., Wilson, J. . r., Wilson, R. . j., Wongjirad, T., Yamada, Y., Yamamoto, K., Yanagisawa, C., Yano, T., Yen, S., Yershov, N., Yokoyama, M., Yoo, J., Yoshida, K., Yuan, T., Yu, M., Zalewska, A., Zalipska, J., Zambelli, L., Zaremba, K., Ziembicki, M., Zimmerman, E. . d., Zito, M., and Żmuda, J.

Subjects
Particle physics, Nuclear and High Energy Physics, chemistry.chemical_element, Pion production, Astronomy & Astrophysics, MASS, Neutrino beam, PION-PRODUCTION, 7. Clean energy, 01 natural sciences, Physics, Particles & Fields, High Energy Physics - Experiment, Nuclear physics, Scattering, Cross section (physics), 0202 Atomic, Molecular, Nuclear, Particle And Plasma Physics, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Neutron, 010306 general physics, Neutrino oscillation, Nuclear Experiment, 0206 Quantum Physics, Charged current, Physics, Science & Technology, hep-ex, 010308 nuclear & particles physics, Detector, Nuclear & Particles Physics, MODEL, 0201 Astronomical And Space Sciences, chemistry, Physical Sciences, High Energy Physics::Experiment, Neutrino, Carbon, Nuclear targets
Abstract

17 pages.- 21 figures, We report a measurement of the nu(mu) charged current quasielastic cross-sections on carbon in the T2K on-axis neutrino beam. The measured charged current quasielastic cross-sections on carbon at mean neutrino energies of 1.94 GeV and 0.93 GeV are (11.95 +/- 0.19(stat)(-1.47)(+1.82)(syst)) x 10(-39) cm(2)/neutron, and (10.64 +/- 0.37(stat)(-1.65)(+2.03)(syst)) x 10(-39) cm(2)/neutron, respectively. These results agree well with the predictions of neutrino interaction models. In addition, we investigated the effects of the nuclear model and the multi-nucleon interaction., It is a pleasure to thank Mr. Taino from Mechanical Support Co. for helping with the construction of INGRID. We thank the J-PARC staff for superb accelerator performance and the CERN NA61 collaboration for providing valuable particle production data. We acknowledge the support of MEXT, Japan; NSERC, NRC and CFI, Canada; CEA and CNRS/IN2P3, France; DFG, Germany; INFN, Italy; National Science Centre (NCN), Poland; RSF, RFBR, and MES, Russia; MINECO and ERDF funds, Spain; SNSF and SER, Switzerland; STFC, UK; and DOE, USA. We also thank CERN for the UA1/NOMAD magnet, DESY for the HERA-B magnet mover system, NII for SINET4, the WestGrid and SciNet consortia in Compute Canada, GridPP, UK. In addition, participation of individual researchers and institutions has been further supported by funds from ERC (FP7), EU; JSPS, Japan; Royal Society, UK; DOE Early Career program, USA.

Published
2015

14. Promising Targets and Current Clinical Trials in Metastatic Non-Squamous NSCLC

Author

Alona Zer and Natasha B. Leighl

Subjects
Cancer Research, Mini Review, medicine.medical_treatment, EGFR, Bioinformatics, NSCLC, lcsh:RC254-282, Receptor tyrosine kinase, intracellular pathways, Targeted therapy, medicine, ROS1, Lung cancer, biology, business.industry, Wnt signaling pathway, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, non-squamous, nuclear targets, Oncology, ALK, Trk receptor, biology.protein, Cancer research, Adenocarcinoma, Personalized medicine, business, novel targets
Abstract

Lung adenocarcinoma is the most common subtype of lung cancer today. With the discovery of epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) rearrangements, and effective targeted therapy, personalized medicine has become a reality for patients with lung adenocarcinoma. Here, we review potential additional targets and novel therapies of interest in lung adenocarcinoma including targets within the cell surface (receptor tyrosine kinases EGFR, human epidermal growth factor receptor 2, RET, ROS1, mesenchymal–epidermal transition, TRK), targets in intracellular signal transduction (ALK, RAS–RAF–MEK, PI3K–AKT–PTEN, WNT), nuclear targets such as poly-ADP ribose polymerase, heat shock protein 90, and histone deacetylase, and selected pathways in the tumor environment. With the evolving ability to identify specific molecular aberrations in patient tumors in routine practice, our ability to further personalize therapy in lung adenocarcinoma is rapidly expanding.

Published
2014
Full Text
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16. Nuclear targets, recoil ion catchers and reaction chambers

Subjects
nuclear targets, SPECTROSCOPY, WHEELS, Physics::Instrumentation and Detectors, BEAM ELECTRON-SPECTRA, Nuclear Experiment, ISOMERS, recoil ions, electron spectrometers
Abstract

The main features of nuclear targets, recoil ion catchers and reaction chambers used in nuclear spectroscopic investigations involving in-beam multi-e-gamma spectrometers are discussed. The relative importance of the F-ray background due to the accelerated ion-target and the recoil-ion-target interaction is estimated. Its impact on the prompt low-energy electron measurements is stressed. Finally a few general features of the interplay between accelerated ion beams, targets and recoil ion catchers particularly relevant for these measurements are broadly discussed and illustrated with typical examples of in-beam e-gamma studies. (C) 1998 Elsevier Science B.V. All rights reserved.

Published
1998

17. Measurement of the nu(mu) charged-current quasielastic cross section on carbon with the ND280 detector at T2K

Author

Abe, K, Adam, J, Aihara, H, Akiri, T, Andreopoulos, C, Aoki, S, Ariga, A, Assylbekov, S, Autiero, D, Barbi, M, Barker, GJ, Barr, G, Bartet-Friburg, P, Bass, M, Batkiewicz, M, Bay, F, Berardi, V, Berger, BE, Berkman, S, Bhadra, S, Blaszczyk, FDM, Blondel, A, Bojechko, C, Bolognesi, S, Bordoni, S, Boyd, SB, Brailsford, D, Bravar, A, Bronner, C, Calland, RG, Caravaca Rodriguez, J, Cartwright, SL, Castillo, R, Catanesi, MG, Cervera, A, Cherdack, D, Chikuma, N, Christodoulou, G, Clifton, A, Coleman, J, Coleman, SJ, Collazuol, G, Connolly, K, Cremonesi, L, Dabrowska, A, De Rosa, G, Danko, I, Das, R, Davis, S, de Perio, P, Dealtry, T, Dennis, SR, Densham, C, Dewhurst, D, Di Lodovico, F, Di Luise, S, Dolan, S, Drapier, O, Duboyski, T, Duffy, K, Dumarchez, J, Dytman, S, Dziewiecki, M, Emery-Schrenk, S, Ereditato, A, Escudero, L, Feusels, T, Finch, AJ, Fiorentini, GA, Friend, M, Fujii, Y, Fukuda, Y, Furmanski, AP, Galymov, V, Garcia, A, Giffin, S, Giganti, C, Gilje, K, Goeldi, D, Golan, T, Gonin, M, Grant, N, Gudin, D, Hadley, DR, Haegel, L, Haesler, A, Haigh, MD, Hamilton, P, Hansen, D, Hara, T, Hartz, M, Hasegawa, T, Hastings, NC, Hayashino, T, Hayato, Y, Hearty, C, Helmer, RL, Hierholzer, M, Hignight, J, Hillairet, A, Himmel, A, Hiraki, T, Hirota, S, Holeczek, J, Horikawa, S, Huang, K, Hosomi, F, Ichikawa, AK, Ieki, K, Ieva, M, Ikeda, M, Imber, J, Insler, J, Intonti, RA, Irvine, TJ, Ishida, T, Ishii, T, Iwai, E, Iwamoto, K, Iyogi, K, Izmaylov, A, Jacob, A, Jamieson, B, Jiang, M, Johnson, S, Jo, JH, Jonsson, P, Jung, CK, Kabirnezhad, M, Kaboth, AC, Kajita, T, Kakuno, H, Kameda, J, Kanazawa, Y, Karlen, D, Karpikov, I, Katori, T, Kearns, E, Khabibullin, M, Khotjantsev, A, Kielczewska, D, Kikawa, T, Kilinski, A, Kim, J, King, S, Kisiel, J, Kitching, P, Kobayashi, T, Koch, L, Kolaceke, A, Koga, T, Konaka, A, Kopylov, A, Kormos, LL, Korzenev, A, Koshio, Y, Kropp, W, Kubo, H, Kudenko, Y, Kurjata, R, Kutter, T, Lagoda, J, Lamont, I, Larkin, E, Laveder, M, Lawe, M, Lazos, M, Lindner, T, Lister, C, Litchfield, RP, Longhin, A, Lopez, JP, Ludovici, L, Magaletti, L, Mahn, K, Malek, M, Manly, S, Marino, AD, Marteau, J, Martin, JF, Martins, P, Martynenko, S, Maruyama, T, Matveev, V, Mavrokoridis, K, Ma, WY, Mazzucato, E, McCarthy, M, McCauley, N, McFarland, KS, McGrew, C, Mefodiev, A, Metelko, C, Mezzetto, M, Mijakowski, P, Miller, CA, Minamino, A, Mineev, O, Mine, S, Missert, A, Miura, M, Moriyama, S, Mueller, TA, Murakami, A, Murdoch, M, Murphy, S, Myslik, J, Nakadaira, T, Nakahata, M, Nakamura, KG, Nakamura, K, Nakamura, KD, Nakayama, S, Nakaya, T, Nakayoshi, K, Nantais, C, Nielsen, C, Nirkko, M, Nishikawa, K, Nishimura, Y, Nowak, J, O'Keeffe, HM, Ohta, R, Okumura, K, Okusawa, T, Oryszczak, W, Oser, SM, Ovsyannikova, T, Owen, RA, Oyama, Y, Palladino, V, Palomino, JL, Paolone, V, Payne, D, Perevozchikov, O, Perkin, JD, Petrov, Y, Pickard, L, Pickering, L, Guerra, ESP, Pistillo, C, Plonski, P, Poplawska, E, Popov, B, Posiadala-Zezula, M, Poutissou, J-M, Poutissou, R, Przewlocki, P, Quilain, B, Radicioni, E, Ratoff, PN, Ravonel, M, Rayner, MAM, Redij, A, Reeves, M, Reinherz-Aronis, E, Riccio, C, Rodrigues, PA, Rojas, P, Rondio, E, Roth, S, Rubbia, A, Ruterbories, D, Rychter, A, Sacco, R, Sakashita, K, Sanchez, F, Sato, F, Scantamburlo, E, Scholberg, K, Schoppmann, S, Schwehr, JD, Scott, M, Seiya, Y, Sekiguchi, T, Sekiya, H, Sgalaberna, D, Shah, R, Shaikhiev, A, Shaker, F, Shaw, D, Shiozawa, M, Shirahige, T, Short, S, Shustrov, Y, Sinclair, P, Smith, B, Smy, M, Sobczyk, JT, Sobel, H, Sorel, M, Southwell, L, Stamoulis, P, Steinmann, J, Still, B, Stewart, T, Suda, Y, Suzuki, A, Suzuki, K, Suzuki, SY, Suzuki, Y, Tacik, R, Tada, M, Takahashi, S, Takeda, A, Takeuchi, Y, Tanaka, HK, Tanaka, HA, Tanaka, MM, Terhorst, D, Terri, R, Thompson, LF, Thorley, A, Tobayama, S, Toki, W, Tomura, T, Touramanis, C, Tsukamoto, T, Tzanov, M, Uchida, Y, Vacheret, A, Vagins, M, Vallari, Z, Vasseur, G, Wachala, T, Wakamatsu, K, Walter, CW, Wark, D, Warzycha, W, Wascko, MO, Weber, A, Wendell, R, Wilkes, RJ, Wilking, MJ, Wilkinson, C, Williamson, Z, Wilson, JR, Wilson, RJ, Wongjirad, T, Yamada, Y, Yamamoto, K, Yanagisawa, C, Yano, T, Yen, S, Yershov, N, Yokoyama, M, Yoo, J, Yoshida, K, Yuan, T, Yu, M, Zalewska, A, Zalipska, J, Zambelli, L, Zaremba, K, Ziembicki, M, Zimmerman, ED, Zito, M, Zmuda, J, Ministerio de Economía y Competitividad (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Natural Sciences and Engineering Research Council of Canada, Centre National de la Recherche Scientifique (France), The Royal Society (UK), and Science and Technology Facilities Council (STFC)

Subjects
Science & Technology, hep-ex, Physics, Delta resonance, Astronomy & Astrophysics, nucl-ex, Nuclear & Particles Physics, Physics, Particles & Fields, High Energy Physics - Experiment, 0201 Astronomical And Space Sciences, 0202 Atomic, Molecular, Nuclear, Particle And Plasma Physics, GEV-C, SINGLE PION-PRODUCTION, NUCLEAR TARGETS, DELTA-RESONANCE, Physical Sciences, EXCITATION, RESONANCE REGION, Single-pion-production, SCATTERING, High Energy Physics::Experiment, EXCHANGE, 0206 Quantum Physics, Nuclear Experiment, TRUE ABSORPTION
Abstract

The Charged-Current Quasi-Elastic (CCQE) interaction, $\nu_{l} + n \rightarrow l^{-} + p$, is the dominant CC process at $E_\nu \sim 1$ GeV and contributes to the signal in accelerator-based long-baseline neutrino oscillation experiments operating at intermediate neutrino energies. This paper reports a measurement by the T2K experiment of the $\nu_{\mu}$ CCQE cross section on a carbon target with the off-axis detector based on the observed distribution of muon momentum ($p_\mu$) and angle with respect to the incident neutrino beam ($\theta_\mu$). The flux-integrated CCQE cross section was measured to be $(0.83 \pm 0.12) \times 10^{-38}\textrm{ cm}^{2}$ in good agreement with NEUT MC value of ${0.88 \times 10^{-38}} \textrm{ cm}^{2}$. The energy dependence of the CCQE cross section is also reported. The axial mass, $M_A^{QE}$, of the dipole axial form factor was extracted assuming the Smith-Moniz CCQE model with a relativistic Fermi gas nuclear model. Using the absolute (shape-only) $p_{\mu}cos\theta_\mu$ distribution, the effective $M_A^{QE}$ parameter was measured to be ${1.26^{+0.21}_{-0.18} \textrm{ GeV}/c^{2}}$ (${1.43^{+0.28}_{-0.22} \textrm{ GeV}/c^{2}}$).

Published
2015

18. Measurements of forward proton production with incident protons and charged pions on nuclear targets at the CERN Proton Synchroton

Author

Jordi Burguet-Castell, G. Giannini, L. Tortora, S.A. Bunyatov, A. Blondel, M. G. Catanesi, M. Kirsanov, E. Tcherniaev, M. Mezzetto, U. Gastaldi, Domizia Orestano, R. Schroeter, G.D. Barr, N. G. Polukhina, V. Tereschenko, E. Di Capua, A. Bagulya, V. Palladino, P. Zucchelli, Ilya Tsukerman, G.P. Skoro, A. Artamonov, A. Guglielmi, C. Meurer, L. Coney, G. Vidal-Sitjes, A. Kayis-Topaksu, L. Howlett, J.S. Graulich, S. Gianì, M. Sorel, Ghislain Grégoire, A. Cervera-Villanueva, G. Prior, R. Tsenov, Rob Edgecock, Ioannis Papadopoulos, C. Wiebusch, M. Bonesini, A. Grossheim, V. Grichine, U. Dore, A. Grant, Claus Gößling, P. Gorbunov, Silvia Borghi, E. Radicioni, Simone Gilardoni, Alexey Krasnoperov, F. Pastore, Malcolm Ellis, A. Ivanchenko, M. Bogomilov, D. W. Schmitz, P. Novella, J. Martín-Albo, D. Gibin, J.J. Gómez-Cadenas, Petar Temnikov, J. Panman, D. Kolev, C. N. Booth, S. Piperov, J. Dumarchez, F. Ferri, Vladimir Ivanchenko, M. C. Morone, B. A. Popov, A. Tonazzo, M. Apollonio, P. Chimenti, F. Bobisut, G. B. Mills, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), APC - Neutrinos, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), HARP, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), UCL - SST/IRMP - Institut de recherche en mathématique et physique, AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Çukurova Üniversitesi, M., Apollonio, A., Artamonov, A., Bagulya, G., Barr, A., Blondel, F., Bobisut, M., Bogomilov, M., Bonesini, C., Booth, S., Borghi, S., Bunyatov, J., Burguet Castell, M., Catanesi, A., Cervera Villanueva, P., Chimenti, L., Coney, E., Di Capua, U., Dore, J., Dumarchez, R., Edgecock, M., Elli, F., Ferri, U., Gastaldi, S., Giani, Giannini, Gianrossano, D., Gibin, S., Gilardoni, P., Gorbunov, C., Gößling, J., Gómez Cadena, A., Grant, J., Graulich, G., Grégoire, V., Grichine, A., Grossheim, A., Guglielmi, L., Howlett, A., Ivanchenko, V., Ivanchenko, A., Kayis Topaksu, M., Kirsanov, D., Kolev, A., Krasnoperov, J., Martín Albo, C., Meurer, M., Mezzetto, G., Mill, M., Morone, P., Novella, D., Orestano, V., Palladino, J., Panman, I., Papadopoulo, F., Pastore, S., Piperov, N., Polukhina, B., Popov, G., Prior, E., Radicioni, D., Schmitz, R., Schroeter, G., Skoro, M., Sorel, E., Tcherniaev, P., Temnikov, V., Tereschenko, A., Tonazzo, L., Tortora, R., Tsenov, I., Tsukerman, G., Vidal Sitje, C., Wiebusch, P., Zucchelli, Blondel, Alain, Borghi, Silvia, Morone, Maria Cristina, Prior, Gersende, Schroeter, Raphaël, Çukurova Üniversitesi, Fen-Edebiyat Fakültesi, Fizik Bölümü, Apollonio, M, Artamonov, A, Bagulya, A, Barr, G, Blondel, A, Bobisut, F, Bogomilov, M, Bonesini, M, Booth, C, Borghi, S, Bunyatov, S, Burguet Castell, J, Catanesi, Mg, Cervera Villanueva, A, Chimenti, P, Coney, L, Di Capua, E, Dore, U, Dumarchez, J, Edgecock, R, Ellis, M, Ferri, F, Gastaldi, U, Giani, S, Giannini, G, Gibin, D, Gilardoni, S, Gorbunov, P, Gossling, C, Gomez Cadenas, Jj, Grant, A, Graulich, J, Gregoire, G, Grichine, V, Grossheim, A, Guglielmi, A, Howlett, L, Ivanchenko, A, Ivanchenko, V, Kayis Topaksu, A, Kirsanov, M, Kolev, D, Krasnoperov, A, Martin Albo, J, Meurer, C, Mezzetto, M, Mills, Gb, Morone, Mc, Novella, P, Orestano, Domizia, Palladino, V, Panman, J, Papadopoulos, I, Pastore, F, Piperov, S, Polukhina, N, Popov, B, Prior, G, Radicioni, E, Schmitz, D, Schroeter, R, Skoro, G, Sorel, M, Tcherniaev, E, Temnikov, P, Tereschenko, V, Tonazzo, A, Tortora, L, Tsenov, R, Tsukerman, I, Vidal Sitjes, G, Wiebusch, C, and Zucchelli, P.

Subjects
Nuclear and High Energy Physics, [PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Physics::Instrumentation and Detectors, proton, nuclear targets, charged pions, FOS: Physical sciences, ddc:500.2, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Basic research, 0103 physical sciences, CERN, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 010306 general physics, Nuclear Experiment, Inelastic proton scattering, Physics, Large Hadron Collider, 010308 nuclear & particles physics, Other reactions above meson production thresholds, [SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Física, Pion-induced reactions, Research council, nuclear target, Physics::Accelerator Physics, HARP Experiment, High Energy Physics::Experiment, Humanities, Particle Physics - Experiment
Abstract

Measurements of the double-differential proton production cross-section d(2 sigma)/dpd Omega in the range of momentum 0.5 GeV/c, We gratefully acknowledge the help and support of the PS beam staff and of the numerous technical collaborators who contributed to the detector design, construction, commissioning and operation. In particular, we would like to thank G. Barichello, R. Brocard, K. Burin, V. Carassiti, F. Chignoli, D. Conventi, G. Decreuse, M. Delattre, C. Detraz, A. Domeniconi, M. Dwuznik, F. Evangelisti, B. Friend, A. Iaciofano, I. Krasin, D. Lacroix, J.-C. Legrand, M. Lobello, M. Lollo, J. Loquet, F. Marinilli, R. Mazza, J. Mulon, L. Musa, R. Nicholson, A. Pepato, P. Petev, X. Pons, I. Rusinov, M. Scandurra, E. Usenko, R. van der Vlugt, for their support in the construction of the detector and P. Dini for his contribution to Monte Carlo production. The collaboration acknowledges the major contributions and advice of M. Baldo-Ceolin, L. Linssen, M.T. Muciaccia and A. Pullia during the construction of the experiment. The collaboration is indebted to V. Ableev, F. Bergsma, P. Binko, E. Boter,M. Calvi, C. Cavion,M.Chizov, A. Chukanov, A. DeSanto, A. DeMin, M. Doucet, D. D¨ullmann, V. Ermilova, W. Flegel, Y. Hayato, A. Ichikawa, O. Klimov, T. Kobayashi, D. Kustov, M. Laveder, M. Mass, H. Meinhard, A. Menegolli, T. Nakaya, K. Nishikawa, M. Paganoni, F. Paleari, M. Pasquali, M. Placentino, V. Serdiouk, S. Simone, P.J. Soler, S. Troquereau, S. Ueda, A. Valassi and R. Veenhof for their contributions to the experiment. We acknowledge the contributions of V. Ammosov, G. Chelkov, D. Dedovich, F. Dydak, M. Gostkin, A. Guskov, D. Khartchenko, V. Koreshev, Z. Kroumchtein, I. Nefedov, A. Semak, J. Wotschack, V. Zaets and A. Zhemchugov to the work described in this paper. The experiment was made possible by grants from the Institut Interuniversitaire des Sciences Nucléaires and the Interuniversitair Instituut voor Kernwetenschappen (Belgium), Ministerio de Educación y Ciencia, Grant FPA2003-06921-c02-02 and Generalitat Valenciana, grant GV00-054-1, CERN (Geneva, Switzerland), the German Bundesministerium für Bildung und Forschung (Germany), the Istituto Nazionale di Fisica Nucleare (Italy), INR RAS (Moscow), the Russian Foundation for Basic Research (grant 08-02-00018), the Bulgarian Mational Science Fund (contract VU-F- 205/2006) and the Particle Physics and Astronomy Research Council (UK). We gratefully acknowledge their support.

Published
2010

19. Electroproduction of Strangeness on Light Nuclei

Author

F. DOHRMANN, D. ABBOTT, A. AHMIDOUCH, P. AMBROZEWICZ, C.S. ARMSTRONG, J. ARRINGTON, R. ASATURYAN, K. ASSAMAGAN, S. AVERY, K. BAILEY, O.K. BAKER, S. BEEDOE, H. BITAO, H. BREUER, D.S. BROWN, R. CARLINI, J. CHA, N. CHANT, E. CHRISTY, A. COCHRAN, L. COLE, G. COLLINS, C. COTHRAN, J. CROWDER, W.J. CUMMINGS, S. DANAGOULIAN, F. DUNCAN, J. DUNNE, D. DUTTA, T. EDEN, M. ELAASAR, R. ENT, L. EWELL, H. FENKER, H.T. FORTUNE, Y. FUJII, L. GAN, H. GAO, K. GARROW, D.F. GEESAMAN, P. GUEYE, K. GUSTAFSSON, K. HAFIDI, J.O. HANSEN, W. HINTON, H.E. JACKSON, H. JUENGST, C. KEPPEL, A. KLEIN, D. KOLTENUK, Y. LIANG, J.H. LIU, A. LUNG, D. MACK, R. MADEY, P. MARKOWITZ, C.J. MARTOFF, D. MEEKINS, J. MITCHELL, T. MIYOSHI, H. MKRTCHYAN, R. MOHRING, S.K. MTINGWA, B. MUELLER, T.G. O’NEILL, G. NICULESCU, I. NICULESCU, D. POTTERVELD, J.W. PRICE, B.A. RAUE, P.E. REIMER, J. REINHOLD, J. ROCHE, P. ROOS, M. SARSOUR, Y. SATO, G. SAVAGE, R. SAWAFTA, R.E. SEGEL, A.YU. SEMENOV, S. STEPANYAN, V. TADEVOSIAN, S. TAJIMA, L. TANG, B. TERBURG, A. UZZLE, S. WOOD, H. YAMAGUCHI, C. YAN, L. YUAN, M. ZEIER, B. ZEIDMAN, and B. ZIHLMANN

Subjects
Physics, Light nucleus, Electroproduction, Nuclear Theory, Strangeness, Hyperons, Spectral function, Nuclear physics, TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY, Nuclear Experiment, Hypernuclear boundstates, Electroproduction of strangeness, Nuclear targets
Abstract

The A(e,e'K+)YX reaction has been investigated in Hall C at Jefferson Laboratory for 6 different targets. Data were taken for Q2)approx 0.35 and 0.5 GeV2) at a beam energy of 3.245GeV for 1)H, 2)H, 3)He, 4)He, C and Al targets. The missing mass spectra are fitted with Monte Carlo simulations taking into account the production of Lambda and Sigma0) hyperon production off the proton, and Sigma-) off the neutron. Models for quasifree production are compared to the data, excess yields close to threshold are attributed to FSI. Evidence for Lambda-hypernuclear bound states is seen for 3,4)He targets.

Published
2004

20. Leptoproduction of cumulative nucleons

Author

Braun, M. A., Vechernin, V. V., and Vlahović, B.

Subjects
nucleon leptoproduction, nuclear targets, Weizsäcker-Williams approximation
Abstract

Leptoproduction of nucleons on nuclear targets into the backward hemisphere is studied at relativistic subasymptotic energies and momenta. Spins are neglected. The relativistic internucleon potential is extracted from the appropriate photoproduction data. Different production mechanisms are shown to work together and interfere. Calculations show that whenever rescattering is possible, it gives the bulk of the contribution, except at very high Q2. The Weizsäcker-Williams approximation is found to generally reproduce only a small part of the total cross-section. Comparison with the data for A(e,e˘p) reaction at E=2.4 GeV shows a reasonable agreement., Proučavamo leptotvorbu nukleona u nukleanrim metama u stražnju polusferu na relativističkim podasimptotskim energijama i impulsima. Zanemarujemo spinove. Relativistički međunukleonski potencijal izvodimo iz odnosnih podataka za fototvorbu. Pokazujemo da je djelotvorno više mehanizama koji interferiraju. Ako je višestruko raspršenje moguće, računi pokazuju da ono i prevladava, izuzev za vrlo velike Q2 . Nalazimo da Weizsäcker-Williamsovo približenje dobro opisuje samo mali dio ukupnog udarnog presjeka. Usporedba s podacima za reakciju A(e,e′p) na E = 2.4 GeV pokazuje dobro slaganje.

Published
2004

21. Hyperon-Nucleon Bound States and Electroproduction of Strangeness on Light Nuclei

Author

Dohrmann, F., Abbott, D., Ahmidouch, A., Ambrozewicz, P., Armstrong, C. S., Arrington, J., Asaturyan, R., Assamagan, K., Avery, S., Bailey, K., Baker, O. K., Beedoe, S., Bitao, H., Breuer, H., Brown, D. S., Carlini, R., Cha, J., Chant, N., Christy, E., Cochran, A., Cole, L., Collins, G., Cothran, C., Crowder, J., Cummings, W. J., Danagoulian, S., Duncan, F., Dunne, J., Dutta, D., Eden, T., Elaasar, M., Ent, R., Ewell, L., Fenker, H., Fortune, H. T., Fujii, Y., Gan, L., Gao, H., Garrow, K., Geesaman, D. F., Gueye, P., Gustafsson, K., Hafidi, K., Hansen, J. O., Hinton, W., Jackson, H. E., Juengst, H., Keppel, C., Klein, A., Koltenuk, D., Liang, Y., Liu, J. H., Lung, A., Mack, D., Madey, R., Markowitz, P., Martoff, C. J., Meekins, D., Mitchell, J., Miyoshi, T., Mkrtchyan, H., Mohring, R., Mtingwa, S. K., Mueller, B., O'Neill, T. J., Niculescu, G., Niculescu, I., Potterveld, D. H., Price, J. W., Raue, B. A., Reimer, P. E., Reinhold, J., Roche, J., Roos, P., Sarsour, M., Sato, Y., Savage, G., Sawafta, R., Segel, R. E., Semenov, A. Y., Stepanyan, S., Tadevosian, V., Tajima, S., Tang, L., Terburg, B., Uzzle, A., Wood, S., Yamaguchi, H., Yan-1, C., Yan-2, C., Yuan, L., Zeier, M., Zeidman, B., and Zihlmann, B.

Subjects
TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY, Electroproduction of strangeness, Nuclear targets, Spectral function
Abstract

The A(e,e'K+)YX reaction has been investigated in Hall C at Jefferson Laboratory for 6 different targets. Data were taken for Q2ࣈ 0.35 and 0.5 GeV2 at a beam energy of 3.245 GeV for 3H, 2H, 2He, C and Al targets. The missing mass spectra are fitted with Monte Carlo simulations taking into account the production of Lambda and Sigma0 hyperon production off the proton, and Sigma- off the neutron. Models for quasifree production are compared to the data, excess yields close to threshold are attributed to FSI. Evidence for Lambda-hypernuclear bound states is seen for 3,4He targets.

Published
2003

22. Crystal Ball Results: Pi- Interactions on Hydrogen and Nuclear Targets

Author

Staudenmeier, H.M., Abaev, V.V., Bekrenev, V.S., Kruglov, S.P., Koulbardis, A.A., Lopatin, I.V., Starostin, A.B., Draper, B., Hayden, S., Huddleston, J., Isenhower, D., Robinson, C., Sadler, M., Allgower, C., Cadman, R., Spinka, H., Comfort, J., Craig, K., Ramirez, A., Kycia, T., Clajus, M., Kozlenko, N.G., Marušić, Aljosa, McDonald, S., Nefkens, B.M.K., Phaisangittisakul, N., Prakhov, S., Price, J.W., Tippens, W.B., Peterson, J., Briscoe, W.J., Shafi, A., Strakovsky, I.I., Manley, D.M., Olmsted, J., Peaslee, D., Knecht, N., Lolos, G., Papandreou, Z., Supek, Ivan, Šlaus, Ivan, Gibson, A., Grosnic, D., Koetke, D., Manweiler, R., and Stanislaus, S.

Subjects
Pi interaction, nuclear targets, Nuclear Theory, Physics::Atomic Physics, Nuclear Experiment
Abstract

Crystal Ball results on Pion interaction with hydrogen and other nuclear targets are given.

Published
2003

23. New results on perturbative colour transparency in quasi-exclusive electroproduction

Author

Jain, Pankaj, Kundu, Bijoy, Ralston, John, and Samuelsson, Jim

Subjects
proton and pion quasi-exclusive electroproduction, nuclear targets, perturbative QCD formalism, hadronic electromagnetic form factors, colour transparency ratio
Abstract

We review the perturbative QCD formalism of hadronic electromagnetic form factors and the colour transparency ratio for quasi-exclusive electroproduction of the proton and pion from nuclear targets. We have completed the first full calculations including all leading-order quark subprocesses and integrations over distribution amplitudes, including Sudakov effects. For the case of the proton, the calculated result shows scaling beyond Q2 = 10 GeV2. The calculation incorporating filtering due to the nuclear medium is cleaner than the corresponding calculation in free space because of attenuation of large distance amplitudes. We find that the colour transparency ratio is rather insensitive to theoretical uncertainties inherent in the perturbative formalism, such as the choice of the hadron distribution amplitude., Opisuje se formalizam perturbativne QCD za hadronske elektromagnetske faktore oblika i omjer providnosti boje poluisključive elektrotvorbe protona i piona u nuklearnim metama. Završili smo prvi potpun račun, uključivši sve vodeće kvarkovske potprocese i integracije preko raspodjelnih amplituda, uključivši i Sudakove učinke. Rezultat za proton pokazuje sličnost dalje od Q2 = 10 GeV2 . Račun s filtriranjem uzrokovanim nuklearnom sredinom je pouzdaniji od odgovarajućeg računa u slobodnom prostoru zbog slabljenja amplituda na velikim udaljenostima. Nalazimo da je omjer providnosti boje vrlo neosjetljiv na teorijske neodređenosti perturbativnog formalizma, kao što je odabir amplitude hadronske raspodjele.

Published
1999

24. Precision-measurement of Structure-function Ratios For Li-6, C-12 and Ca-40

Author

Amaudruz, P., Arneodo, M., Arvidson, A., Badelek, B., Baum, G., Beaufays, J., Bird, I. G., Botje, M., Broggini, C., Bruckner, W., Brull, A., Burger, W. J., Ciborowski, J., Vandantzig, R., Dobbeling, H., Domingo, J., Drinkard, J., Engelien, H., Ferrero, M. J., Fluri, L., Grafstrom, P., Vonharrach, D., Vanderheijden, M., Heusch, C., Ingram, Q., Janson, K., Dejong, M., Kabuss, E. M., Kaiser, R., Ketel, T. J., Klein, F., Korzen, B., Kruner, U., Kullander, S., Landgraf, U., Lettenstrom, F., Lindqvist, T., Mallot, G. K., Mariotti, C., Vanmiddelkoop, G., Mizuno, Y., Nassalski, J., Nowotny, D., Pavel, N., Peroni, Cristiana, Peschel, H., Povh, B., Rieger, R., Rith, K., Rohrich, K., Rondio, E., Ropelewski, L., Sandacz, A., Scholz, C., Schumacher, R., Sennhauser, U., Sever, F., Shibata, T. A., Siebler, M., Simon, A., Staiano, A., Taylor, G., Treichel, M., Vuilleumier, J. L., Walcher, T., Windmolders, R., and Zetsche, F.

Subjects
ELECTRON-SCATTERING, INELASTIC MUON SCATTERING, NUCLEAR TARGETS, IRON TARGETS, DEUTERIUM
Published
1992

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