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Your search keyword '"Paiardi, Silvia"' showing total 106 results
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106 results on '"Paiardi, Silvia"'

3. A strange chest pain after dental surgery

Author

Porteri, Enzo, Rizzardi, Nicola, Rizzoni, Damiano, Salvi, Andrea, De Ciuceis, Carolina, Farina, Davide, Boari, Gianluca E. M., Platto, Caterina, Paiardi, Silvia, Raed, Almajdalawi, and Agabiti Rosei, Enrico

Published
2008
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8. Intracellular molecular effects of insulin resistance in patients with metabolic syndrome

Author

Pasini Evasio, Flati Vincenzo, Paiardi Silvia, Rizzoni Damiano, Porteri Enzo, Aquilani Roberto, Assanelli Deodato, Corsetti Giovanni, Speca Silvia, Rezzani Rita, De Ciuceis Carolina, and Agabiti-Rosei Enrico

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Aim of the study Patients with metabolic syndrome (MetS) have an increased risk of cardiovascular disease. Data obtained from muscle biopsies have demonstrated altered insulin signaling (IS) in patients with MetS. The IS regulates critical cell functions including molecular-regulated cellular metabolite fluxes, protein and energetic metabolism, cell proliferation and apoptosis with consequent regulation of cell life including endothelial homeostasis and blood coagulation. However, little is known about blood cell IS in MetS patients. The aim of this study was to develop a method to evaluate IS in peripheral lymphocytes to identify altered intracellular molecules in patients with MetS to use as risk biomarkers of vascular thrombosis. Patients and Methods We investigated 40 patients with MetS and 20 controls. MetS was defined according to guidelines from the US National Cholesterol Education Program Adult Treatment Panel III. Blood samples were taken from all participants. Total mononuclear cells were isolated from peripheral blood using density gradient centrifugation. IS molecules were evaluated using Western blot analysis followed by computer-assisted densitometer evaluation. Results Lymphocytes of MetS patients showed a reduced mTOR expression (the mammalian target of rapamycin) which is a fundamental molecule of IS. Major impairment of IS was confirmed by reduced upstream and downstream mTOR molecules which regulate fundamental cells metabolic functions. Conclusions In patients with MetS, we found a reduction of mTOR and other mTOR-related molecules involved in insulin resistance, cell repair, coagulation and vasculogenesis. A reduced expression of mTOR may reflect an increased risk of vascular thrombosis.

Published
2010
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9. A sneaky case of endocarditis

Author

Pagani, Laura, Marra, Serena, Paiardi, Silvia, Ricevuti, Giovanni, and Bressan, Maria Antonietta

Abstract

The clinical history of infective endocarditis is highly variable depending on the pathogen detected, the presence/absence of pre-existing cardiac disease and way of presentation. Therefore infective endocarditis suspicion should be placed in different clinical situations. Infective endocarditis may have an acute and rapidly progressive course, but it can also occur in subacute or chronic low-grade fever and nonspecific symptoms, making difficult the initial clinical evaluation. In the elderly or immunocompromised patients infective endocarditis often has an atypical onset, less frequently accompanied by a fever than is seen in younger subjects. In this category of patients the disease should be suspected and implement appropriate investigations to rule out the presence of infective endocarditis., Bollettino della Società Medico Chirurgica di Pavia, Vol 127, N° 1 (2014)

Published
2014
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10. Larynx traumatic injuries: small traumas great damage

Author

Pagani, Laura, Marra, Serena, Paiardi, Silvia, Ricevuti, Giovanni, and Bressan, Maria Antonietta

Abstract

Larynx traumatic injuries include a mix of clinical features for severity and aetiology; they involve more or less marked larynx anatomy and functions alterations. Respiratory distress must be treated efficiently and early; in most situations phonatory abnormalities function represent an element almost constant, not to be underestimated to avoid disabling outcomes that can significantly affect patient life quality. The external laryngeal trauma of clinical relevance are relatively uncommon in the literature is in fact reported an incidence between 1 in 124,000 and 1 in 137,000 injuries related to a general emergency department. They continue to represent a potentially serious condition because of the high risk of mortality and morbidity in acute., Bollettino della Società Medico Chirurgica di Pavia, Vol 127, N° 1 (2014)

Published
2014
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11. Utility of ultrasound integrated in a case of acute dyspnea

Author

Martino, Ilaria Francesca, Marra, Serena, Statti, Giulia, Negri, Simona, and Paiardi, Silvia

Subjects
cardiovascular system
Abstract

Grave respiratory insufficiency is a frequent cause of access to the emergency department and represents one of the most critical patient conditions. Differential diagnosis should aim to distinguish especially between cardiac and non-cardiac dyspnea. Thoracic ecography is more and more employed as a quick and user-friendly diagnostic method, based on finding specific artifacts for the identification of specific pathological conditions. In particular, thoracic ecography along with the analysis of the vena cava and heart chambers would allow to distinguish between a cardiac and non-cardiac grave dyspnea., Bollettino della Società Medico Chirurgica di Pavia, Vol 126, N° 3 (2013)

Published
2013
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12. Atrial fibrillation management at the emergency department

Author

Marra, Serena, Anesi, Ernesto, Negri, Simona, Pagani, Laura, Paiardi, Silvia, Resasco, Tullia, Ferrari, Ilaria, and Bressan, Maria Antonietta

Subjects
humanities
Abstract

Atrial fibrillation (AF) is the most frequent sustained arrhythmia; it is a subventricular tachyarrhytmia, characterized by a chaotic and irregular electric atrial activity that causes the loss of the mechanical function of the atrial contraction. It often represents cause of access to the emergency department, since it is perceived by the patient (palpitation, dyspnea) in over 70% of cases. Its treatment is strongly linked to the period of time passed since its onset, so that a quick identification, and especially a prompt and focused therapeutic intervention, can effectively resolve the disease. In this retrospective study we analyzed the therapeutic approach, seen as a rhythm-reactivation strategy, adopted at the Emergency Department of the San Matteo IRCCS Foundation., Bollettino della Società Medico Chirurgica di Pavia, Vol 126, N° 3 (2013)

Published
2013
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32. Dermal microvascular rarefaction in hypertensive patients

Author

Porteri, Enzo, Paiardi, Silvia, Rodella, Luigi Fabrizio, Rizzoni, Damiano, DE CIUCEIS, Carolina, Boari, Gianluca, Rezzani, Rita, Zani, Francesca, Miclini, Marco, Ricci, Francesca, Bianchi, Rossella, and AGABITI ROSEI, Enrico

Published
2006

36. Microvascular rarefaction in the derma of hypertensive patients

Author

Rizzoni, Damiano, Porteri, Enzo, Paiardi, Silvia, Rodella, Luigi Fabrizio, DE CIUCEIS, Carolina, Boari, Gianluca, Rezzani, Rita, Zani, Francesca, Miclini, Marco, Ricci, Francesca, Bianchi, Rossella, and AGABITI ROSEI, Enrico

Published
2006

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