1. Primary retroperitoneal acinar cell cystadenoma
- Author
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Enrico Facci, Giuseppe Zamboni, Luigi Romano, Paola Castelli, and Anna Pesci
- Subjects
Pathology ,medicine.medical_specialty ,Cystoadenoma ,retroperitoneum ,acinar cell ,medicine.medical_treatment ,Cystadenoma ,Acinar Cells ,digestive system ,Disease-Free Survival ,Pathology and Forensic Medicine ,Diagnosis, Differential ,stomatognathic system ,Laparotomy ,Lymphangioma ,Biomarkers, Tumor ,Acinar cell ,medicine ,Humans ,Trypsin ,Retroperitoneal Neoplasms ,business.industry ,Pancreatic Acinar Cell Cystadenoma ,Middle Aged ,medicine.disease ,Cystic Neoplasm ,body regions ,Treatment Outcome ,medicine.anatomical_structure ,Immunohistochemistry ,Female ,Lymphangioma, Cystic ,Differential diagnosis ,Pancreas ,business - Abstract
In this report, we describe a case of hitherto unreported primary retroperitoneal acinar cell cystadenoma that morphologically and immunophenotypically resembled pancreatic acinar cell cystadenoma. Pancreatic acinar cell cystadenoma is a very uncommon benign lesion characterized by acinar cell differentiation, the evidence of pancreatic exocrine enzyme production, and the absence of cellular atypia. Our case occurred in a 55-year-old woman presenting a 10-cm multilocular cystic lesion in the retroperitoneum thought to be a mucinous cystic neoplasm. At laparotomy, the cystic mass, which showed no connection with any organ, was completely resected with a clinical diagnosis of cystic lymphangioma. The diagnosis of retroperitoneal acinar cell cystadenoma was based on the recognition of morphological acinar differentiation, the immunohistochemical demonstration of the acinar marker trypsin, and the absence of cellular atypia. These peculiar features can be used in the differential diagnosis with all the other cystic lesions of the retroperitoneum.
- Published
- 2012