295 results on '"Pattnaik, B."'
Search Results
2. Economic Impact of FMD in cattle and buffaloes in India
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GOVINDARAJ G, GANESH KUMAR B, KRISHNAMOHAN A, RAVEENDRA HEGDE, NANDAKUMAR S, KOKILA PRABHAKARAN, VINAY MOHAN, NARESH KAKKER, LOKHANDE T, KRISHNA SHARMA, AMIT KANANI, LIMAYE A, NATCHIMUTHU K, TANVEER AHMED KHAN, JYOTI MISRI, DASH B B, PATTNAIK B, and RAHMAN H
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Bovines ,Financial loss ,FMD ,India ,Animal culture ,SF1-1100 - Abstract
In India, among various diseases that limit livestock production, Foot and Mouth Disease (FMD) stands first and affects thousands of animals every year. The estimation of loss due to FMD is of paramount importance for designing appropriate control plans. The economic impact studies on various livestock diseases including FMD are very minimal and hence this study assessed the economic loss due to FMD in cattle and buffaloes in few states and overall loss in the country. The total loss estimated comprise of milk yield reduction, unavailability of draught power, distress sale, treatment cost, mortality and opportunity cost of labour based on primary survey undertaken in 10 states and one Union territory. The results revealed that there was variation in loss levels between species and among the study states due to variation in disease incidence and severity levels, productive capacity of the animals, animal health infrastructure in the respective states, etc. The total estimated loss due to FMD in cattle and buffalo was INR 20,897 crore during 2013-14 with wide variation in magnitude across the states studied. The study provided empirical evidence of loss due to FMD in cattle and buffaloes in few states and overall loss in the country.
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- 2020
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3. Antigenic and genetic comparison of foot-and-mouth disease virus serotype O Indian vaccine strain, O/IND/R2/75 against currently circulating viruses
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Mahapatra, Mana, Yuvaraj, S., Madhanmohan, M., Subramaniam, S., Pattnaik, B., Paton, D.J., Srinivasan, V.A., and Parida, Satya
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- 2015
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4. Development of single-chain Fv against the nucleoprotein of type A influenza virus and its use in ELISA
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Sengupta, Devyani, Shaikh, Asma, Bhatia, S., Pateriya, A.K., Khandia, R., Sood, R., Prakash, A., Pattnaik, B., and Pradhan, H.K.
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- 2014
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5. Porcine sapelovirus among diarrhoeic piglets in India
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Ray, P. K., Desingu, P. A., Kumari, S., John, J. K., Sethi, M., Sharma, G. K., Pattnaik, B., Singh, R. K., and Saikumar, G.
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- 2018
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6. Quantitative characteristics of the foot‐and‐mouth disease carrier state under natural conditions in India
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Hayer, S. S., Ranjan, R., Biswal, J. K., Subramaniam, S., Mohapatra, J. K., Sharma, G. K., Rout, M., Dash, B. B., Das, B., Prusty, B. R., Sharma, A. K., Stenfeldt, C., Perez, A., Rodriguez, L. L., Pattnaik, B., VanderWaal, K., and Arzt, J.
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- 2018
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7. Large outbreak of cholera caused by El Tor variant "Vibrio cholerae" O1 in the eastern coast of Odisha, India during 2009
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PAL, B. B., KHUNTIA, H. K., SAMAL, S. K., KERKETTA, A. S., KAR, S. K., KARMAKAR, M., and PATTNAIK, B.
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- 2013
8. "ONE HEALTH" CONCEPT TO MITIGATE ZOONOSES: INDIAN PERSPECTIVE.
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Ranganatha, S., Kumar, H. B. Chethan, Rathnamma, D., Shyamsundar, K. A., Pattnaik, B., Yadav, M. P., Suresh, K. P., Siju, S. J., Hiremath, J., Nayakvadi, S., and Patil, Sharanagouda S.
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ZOONOSES ,ANTI-infective agents ,POLLUTION ,VETERINARY services ,PUBLIC health - Abstract
While the interfaces between animal, human, plant, and environmental arenas have many positive effects and outcomes, they have also led to an increased incidence of zoonoses and multifactorial chronic diseases. Effectively addressing these diseases requires interdisciplinary and intersectoral knowledge and skills to counter the development of antimicrobial resistance (AMR) and environmental pollution/contamination, ensuring food safety, sound health, and wellness. According to the "One Health (OH)" concept put forth by the Food and Agriculture Organization (FAO), the World Health Organization (WHO), and the World Organization for Animal Health (WOAH), multisectoral cooperation is necessary for the best possible health of humans, animals, and the environment. Collaboration should encompass local, national, and international organizations involved in human and veterinary public health, forestry, and environmental health. In India, the idea of OH is still in its infancy but is growing gradually. "Using the One Health (OH) approach, the Indian government has taken steps to address pressing issues such as antimicrobial resistance, zoonotic illnesses, and food safety, despite encountering several obstacles. The main challenges in adopting the One Health approach include the absence of a legal framework, poor coordination between various public and private organizations, insufficient animal disease surveillance, inadequate mechanisms for timely data collection and sharing across sectors, challenges with neighboring South Asian Association for Regional Cooperation (SAARC) countries, and a lack of funding. To effectively leverage the One Health approach in combating the rising incidence of zoonotic diseases, there is an urgent need to implement systematic zoonotic disease surveillance. This should include regulated antibiotic use among humans, animals, and crop agriculture. Additionally, it is crucial to develop a national zoonotic disease registry and establish a comprehensive network involving academic, research, pharmaceutical, and various other stakeholders from different sectors at both national and regional levels. The role of inter-sectoral cooperation in integrating and enhancing the global health system is widely acknowledged. However, its application to One Health (OH) is not yet evident. To successfully implement the 'OH' concept, there is an urgent need for establishing collaboration due to the growing complexity of the health system. This review explores various 'OH' collaboration models and considers which model could be most effective for India's healthcare system. The review process involved three steps: a) identification of crucial OH collaboration strategies, b) documentation of worldwide activities in OH and allied disciplines, and c) scoping these into India's OH initiatives. [ABSTRACT FROM AUTHOR]
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- 2023
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9. Inhibition of mitochondrial β-oxidation by miR-107 promotes hepatic lipid accumulation and impairs glucose tolerance in vivo
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Bhatia, H, Pattnaik, B R, and Datta, M
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- 2016
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10. In vitro Adoption and Propagation of High Pathogenic Avian Influenza (HPAI) Virus Subtype H5N1 in non-avian Host System
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Maheswarappa Gowrakkal, Byregowda S.M., Pradhan H.K., Tosh C., Pattnaik B., and Renukaprasad C.
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Veterinary medicine ,SF600-1100 - Abstract
The paradigmatic, fatal and devastating ailment called avian influenza or bird flu is a highly contagious viral disease caused by type A influenza virus, It primarily affects the respiratory, digestive and/or nervous system of chickens, turkeys, guinea fowls and other avian species and less commonly pigs and other species of mammals including human. In India, The first pandemic outbreak of Avian Influenza was reported during 2006. In this study, we selected an isolate of high pathogenic avian influenza (A/Ck/Jalgaon/India/12419/2006) H5N1 virus and propagated in chicken embryo fibroblast. Later this virus was adopted and propagated in Madin-Darby canine kidney cells (MDCK) and Vero cells. Infected non-avian cells with an avian virus shown cytopathic effects like rounding, cytoplasmic elongation, syncytia formation and later stages fluffing from the attached surface. The harvested virus suspension shown increased haemagglutination titre (HA) than viral suspension from chicken embryo fibroblast culture and the presence of virus was confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR). The obtained result reveals that virus had capacity to adopt for the invitro culture and propagate in non avian host cells with higher titre. This infers the chance of virus to cross the host barrier and probable chance of infection in human being.
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- 2014
11. Association of BoLA DRB3 alleles with variability in immune response among the crossbred cattle vaccinated for foot-and-mouth disease (FMD)
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Gowane, G.R., Sharma, A.K., Sankar, M., Narayanan, K., Das, Biswajit, Subramaniam, S., and Pattnaik, B.
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- 2013
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12. Phylogenetic analysis revealed genetic similarity of the H5N1 avian influenza viruses isolated from HPAI outbreaks in chickens in Maharashtra, India with those isolated from swan in Italy and Iran in 2006
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Pattnaik, B., Pateriya, A. K., Khandia, R., Tosh, C., Nagarajan, S., Gounalan, S., Murugkar, H. V., Shankar, B. P., Shrivastava, N., Behera, P., Bhagat, S., Peiris, J. S. M., and Pradhan, H. K.
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- 2006
13. Detection of proviral genomic sequence of bovine immunodeficiency virus in Indian cattle
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Patil, S. S., Pattnaik, B., Mishra, N., Banumathi, N., Dubey, Renu, and Pradhan, H. H.
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- 2003
14. Experimental Studies on Marek's Disease in Japanese Quail (Coturnix Coturnix Japonica)
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Pradhan, H. K., Mohanty, G. C., Mukit, A., and Pattnaik, B.
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- 1987
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15. Antinuclear Antibody in Chickens with Reoviral Arthritis
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Pradhan, H. K., Mohanty, G. C., Kataria, J. M., Pattnaik, B., and Verma, K. C.
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- 1987
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16. Evaluation of Genetic and Environmental Parameters Determining Antibody Response Induced by Vaccination Against Foot and Mouth Disease
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Gowane, G. R., Sharma, A. K., Sankar, M., Thirumurugan, P., Narayanan, K., Subramaniam, S., and Pattnaik, B.
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- 2013
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17. Polycythemia vera presenting with bilateral papilledema: A rare case report
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Parija S, Mohapatra M, and Pattnaik B
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Papilledema ,polycythemia vera ,sagittal sinus thrombosis ,Ophthalmology ,RE1-994 - Abstract
A 45-year-old male patient presented with gradual onset of headache, vomiting and blurring of vision of 28 days duration. Ophthalmological examination revealed normal anterior segment and pupillary reflex. No abnormality was detected in the vitreous. Optic disc showed features of advanced papilledema with normal macula and retinal periphery in both eyes. Visual acuity was 20/200 in the right eye and counting fingers close range in the left eye. Non-contrast computed tomography of brain was normal and magnetic resonance imaging showed sagittal sinus thrombosis without any evidence of venous infarction or intracranial mass. Routine hematological investigations revealed increased hemoglobin level, packed cell volume and leucocytosis. Further investigation revealed increased Vitamin B12 and decreased serum erythropoietin. A diagnosis of polycythemia vera was made from the above findings. This case is being presented for the rarity of association of polycythemia vera with bilateral advanced papilledema due to sagittal sinus thrombosis.
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- 2008
18. Development of a capsid based competitive inhibition enzyme-linked immunosorbent assay for detection of bovine immunodeficiency virus antibodies in cattle and buffalo serum
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Bhatia, S., Sood, Richa, Bhatia, A.K., Pattnaik, B., and Pradhan, H.K.
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- 2008
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19. Development and evaluation of a MAb based competitive-ELISA using helicase domain of NS3 protein for sero-diagnosis of bovine viral diarrhea in cattle and buffaloes
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Bhatia, S., Sood, Richa, Mishra, N., Pattnaik, B., and Pradhan, H.K.
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- 2008
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20. Genetic analysis of H9N2 avian influenza viruses isolated from India
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Tosh, C., Nagarajan, S., Behera, P., Rajukumar, K., Purohit, K., Kamal, R. P., Murugkar, H. V., Gounalan, S., Pattnaik, B., Vanamayya, P. R., Pradhan, H. K., and Dubey, S. C.
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- 2008
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21. Analysis of the PB2 gene reveals that Indian H5N1 influenza virus belongs to a mixed-migratory bird sub-lineage possessing the amino acid lysine at position 627 of the PB2 protein
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Kamal, R. P., Tosh, C., Pattnaik, B., Behera, P., Nagarajan, S., Gounalan, S., Shrivastava, N., Shankar, B. P., and Pradhan, H. K.
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- 2007
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22. Development and evaluation of SYBR Green I-based one-step real-time RT-PCR assay for detection and quantification of Chikungunya virus
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Santhosh, S.R., Parida, M.M., Dash, P.K., Pateriya, A., Pattnaik, B., Pradhan, H.K., Tripathi, N.K., Ambuj, S., Gupta, N., Saxena, P., and Lakshmana Rao, P.V.
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- 2007
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23. The safety and efficacy of the oral rabies vaccine SAG2 in Indian stray dogs
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Cliquet, F., Gurbuxani, J.P., Pradhan, H.K., Pattnaik, B., Patil, S.S., Regnault, A., Begouen, H., Guiot, A.L., Sood, R., Mahl, P., Singh, R., Meslin, F.X., Picard, E., Aubert, M.F.A., and Barrat, J.
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- 2007
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24. Development and evaluation of SYBR Green I-based one-step real-time RT-PCR assay for detection and quantitation of Japanese encephalitis virus
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Santhosh, S.R., Parida, M.M., Dash, P.K., Pateriya, A., Pattnaik, B., Pradhan, H.K., Tripathi, N.K., Ambuj, S., Gupta, N., Saxena, P., and Lakshmana Rao, P.V.
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- 2007
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25. Status of Foot-and-mouth Disease in India
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Subramaniam, S., Pattnaik, B., Sanyal, A., Mohapatra, J. K., Pawar, S. S., Sharma, G. K., Das, B., and Dash, B. B.
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- 2013
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26. Identification of other Cellular Receptors for Edema Factor of Bacillus anthracis by Independent Inhibition of Protective Evidenced by Inhibition of Embryo Growth and Antigen Angiogenesis.
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Khandia, R., Pattnaik, B., Rajukumar, K., Pateriya, A. K., Puranik, N., Bhatia, S., and Murugkar, H.
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CHICKEN embryos ,MET receptor ,BACILLUS anthracis ,HEPATOCYTE growth factor ,VASCULAR endothelial growth factors ,NEOVASCULARIZATION - Abstract
Edema factor (EF) is one of the major secretory proteins of anthrax bacteria along with protective antigen (PA) and lethal factor (LF). Edema factor is a calmodulin-and calcium-dependent adenylate cyclase that increases intracellular levels of cAMP. Intracellular trafficking of EF occurs through PA by binding to ATR/CMG2 receptors, which are also involved in other physiological functions of cells. cAMP is a secondary messenger which activates multiple signaling cascades involved in the cytokinetics of actin molecules and cell junction formation. The present study evaluated the effect of EF on growth and angiogenesis patterns in chicken embryos in the in ovo model. Angiogenesis in the chorioallantoic membrane (CAM) of an embryonated chicken egg was decreased and embryo growth was delayed by EF despite the absence of trafficking moiety PA, which is required for transferring the EF molecule inside the cell. Angiogenesis inhibition and embryo growth retardation indicate the use of an alternative receptor by EF to modulate these cellular functions. Additionally, docking was performed between EF as a ligand and hepatocyte growth factor receptor (cMET) and vascular endothelial growth factor (VEGF) receptors, which are mainly involved in growth and angiogenesis. The analysis revealed a very strong binding of EF to cMET receptor (in terms of the number of hydrogen bonds and energy) compared to its ligand hepatocyte growth factor (HGF), which indicates the use of cMET receptor by EF and induction of angiogenesis and embryo growth retardation possibly by competitive inhibition of HGF ligand or receptormediated endocytosis. [ABSTRACT FROM AUTHOR]
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- 2021
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27. Serotype C foot-and-mouth disease virus isolates from India belong to a separate so far not described lineage
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Hemadri, D, Sanyal, A, Tosh, C, Venkataramanan, R, and Pattnaik, B
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- 2003
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28. Contributory presentations/posters
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Gries, A., Singh, Balwinder, Nakazawal, Chicko, Genest, D., Getzoff, E. D., Matsuo, H., Kaur, Harpreet, Borst, J. W., Chadha, K. C., Tingyun, Kuang, Jagannadham, M. V., Leijon, Mikael, Sato, S., Bhakuni, Vlnod, Vijayan, M., Surolia, A., Suguna, K., Manoj, N., Srinivas, V. R., Ravishankar, R., Laggner, P., Prassl, R., Schwarzenbacher, R., Zeth, K., Kostner, G. M., Taylor, Susan S., Xuong, Nguyen-huu, Akamine, Pearl, Sagar, Bidva M., Saikrishnan, K., Purnapatre, K., Handa, P., Roy, S., Varshney, U., Biswal, B. K., Sukumar, N., Rao, J. K. Mohana, Johnson, A., Pattabhi, Vasantha, Murthy, M. R. N., Krishna, Sri S., Savithri, H. S., Sastri, Mira, Hosur, M. V., Pillai, Bindu, Kannan, K. K., Kumar, Mukesh, Patwardhan, Swati, Padmanabhaa, B., Sasaki-Sugio, S., Matsuzaki, T., Nukaga, M., Singh, T. P., Sharma, A. K., Srinivasan, A., Khan, J. A., Paramasivam, M., Kumar, P., Karthikevan, S., Sharma, S., Yadav, S., Srintvasan, A., Alam, Neelima, Gourinath, S., Kaur, Punit, Chandra, Vikas, Betzel, Ch., Ghosh, S., Bera, A. K., Pal, A. K., Baneriee, Asok, Mukhopadhyay, B. P., Bhattacharya, S., Chakraborty, S., Haldar, U., Dey, I., Solovicova, Adriana, Sevcik, Jozef, Sekar, K., Sundaralingam, M., Genov, N., Liang, Dong-cai, Zhang, Ji-ping, Jiang, Tao, Chang, Wen-rui, Blommers, Marcel, Jahnke, Wolfgang, Hosur, R. V., Panchal, S. C., Pillay, Bindu, Jaganathan, N. R., Mathur, Puniti, Srivatsun, S., Joshi, Ratan Mani, Chauhan, V. S., Govil, Girjesh, Atreya, H. S., Sahu, S. C., Quinjou, Éric, Adjadj, Elisabeth, Mispelter, Joël, Izadi-Pruneyre, Nadia, Blouquit, Yves, Heyd, Bernadette, Lerat, Guilhem, Desmadreil, Michel, Milnard, Philippe, Lin, Y., Rao, B. D. Nageswara, Raghunathan, Vidva, Chau, Mei H., Coutinho, Evans, Pesais, Prashant, Srivastava, Sudha, Saran, Anil, Srikrishnan, Thamarapu, Lijima, Herbert, Gesme, Jayson, Sapico, Leizl F., Paxton, Raymond, Grace, C. R., Nagenagowda, G., Lynn, A. M., Cowsik, Sudha M., Govil, G., Sahu, Sarata C., Bhattacharya, A., Chauhan, S., Kumar, Anil, Zuiderweg, Erik R. P., Pellecchia, Maurizio, Nitta, Katsutoshi, Ohnishi, Atsushi, Kawano, Keiichi, Hikichi, Kunio, Fujitani, Naoki, Ohkubo, Tadayasu, Aizawa, Tomoyasu, Kumaki, Yasuhiro, Hayakawa, Yoichi, Parvathy, Rani V., Kini, R. M., Nakagawa, Astushi, Tanaka, Isao, Demura, Makoto, Yao, Min, Koshiba, Takumi, Kobashigawa, Yoshihiro, Kuwajima, Kunihiro, Linge, Jens, Nilges, Michael, Donoghue, Seán O., Chakshusmathi, G., Ratnaparkhi, Girish S., Madhu, P. K., Varadarajan, R., Tetreau, C., Tourbez, M., Lavalette, D., Bulone, D., Manno, M., Emanuele, A., Palma-Vittorelli, M. B., Palma, M. U., Vaiana, S. M., Martorana, V., Biagio, P. L. San, Chang, D. K., Cheng, S. F., Yang, S. H., Francis, S., Trivedi, V. D., Chien, W. J., Manstein, Dietmar J., Batra, Renn, Geeves, Michael A., Geller, Maciej, Trvlska, Joanna, Grochowski, Pawel, Lesyng, B., Ginalski, K., Grochowski, P., Lavalette, P., Blouquit, Y., Roccatano, D., Berendsen, H. J. C., Amadei, A., Nola, Di A., Ho, Bosco, Curmi, P. M. G., Berry, H., Pelta, J., Pauthe, E., Lairez, D., Srinivasan, M., Sahi, Shakti, Kothekar, V., Madhusudnan, Kartha S., Nandel, Fateh S., Jain, D. V. S., Berendsen, Herman J. C., Feenstra, Anton K., Tama, F., Sanejouand, Y.-H., Go, N., Sharma, Deepak, Pasha, Santosh, Sharma, Sunita, Brahmachari, Samir K., Makker, Jyoti, Viiavaraghavan, R., Kumar, S., Dey, Sharmisllia, Krishnamoorthy, G., Lakshmikanth, G. S., Zaitseva, E. M., Mazhul, V. M., Kierdaszuk, Borys, Widengren, J., Rigler, R., Terry, B., Mets, Ü., Swaminathan, R., Yathindra, N., Thamotharan, S., Chosrowjan, H., Mataga, N., Shibata, Y., Morisima, I., Xiao, Ming, Selvin, Paul, Chakraharty, Tania, Cooke, Roger, Faraone, A., Branca, C., Maisano, G., Migliardo, P., Magazù, S., Villari, V., Behere, Digambar V., Deva, Sharique Zahida Waheed M., Vallone, B., Savino, C., Travaglini-Allocatelli, C., Cutruzzolà, F., Brunori, M., Gibson, Q. H., Mazumdar, Shyamalava, Mitra, Samaresh, Prasad, Swati, Soto, P., Fayad, R., Tyulkova, N. A., Sukovataya, I. E., Mamedov, Sh. V., Aksakal, B., Canturk, M., Aktas, B., Yilgin, R., Bogutska, K. I., Miroshnichenko, N. S., Wein, A. J., Hypolite, J. A., DiSanto, M., Chacko, S., Zheng, Y-M., Antosiewicz, J., Wojciechowski, M., Grycuk, T., Di Nola, Alfredo, Ceruso, Marc A., Chatterjee, Bishnu P., Bandvopadhvay, Subhasis, Choudhury, Devapriva, Khight, Stefan, Thompson, Andrew, Stojanoff, Vivian, Pinkner, Jerome, Hultgren, Scott, Flatters, Delphine, Goodfellow, Julia, Takazawatt, Fumi, Kanehisa, Minoru, Sasai, Masaki, Nakamura, Hironori, Wang, Bao Han, Pan, xin Min, Zheng, Yuan, Wang, Zhi Xin, Ahmad, Atta, Kulkarni, Sangeeta, Prakash, Koodathingal, Prajapati, Shashi, Surin, Alexey, Kihara, Hiroshi, Yang, Li, Matsumoto, Tomoharu, Nakagawa, Yuki, Semisotnov, Gennady V., Kimura, Kazumoto, Amemiya, Yoshiyuki, Tayyab, Saad, Muzammil, Salman, Kumar, Yogesh, Bhakuni, Vinod, Sundd, Monica, Kundu, Suman, Jagannadham, Medicherla V., Chandani, Bina, Warrier, Deepti, Sinha, Lalankumar, Dhar, Ruby, Mehrotra, Sonam, Khandelwal, Purnima, Seth, Subhendu, Gidwani, Arun, Prabha, Ratna C., Sasidhar, Y. U., Madhusudan, K. P., Nishikawa, Ken, Kinjo, Akira R., Varadarajan, Raghavan, Chakravarty, Suvobrata, Van Dael, H., Noyelle, K., Joniau, M., Haezebrouck, P., Jha, Indra Brata, Bhat, Rajiv, Dash, Sheffali, Mohanty, Prasanna, Bandyopadhyay, A. K., Sonawat, H. M., Rao, Ch. Mohan, Datta, Siddhartha, Raman, B., Rajaraman, K., Ramakrishna, T., Pande, A., Benedek, G., King, J., Betts, S., Pande, J., Asherie, N., Ogun, O., Kalacheva, G. S., Sokolova, I. V., Mitaku, Shigeki, Sonoyama, Masashi, Taira, Kunihiro, Yokoyama, Yasunori, Sasakil, Takanori, Kamo, Naoki, Mukai, Yuri, Dalal, Seema, Regan, Lynne, Mituku, Shigeki, Kumar, Devesh, Roychoudhury, Mihir, Lőrinczv, Dénes, Könczöl, Franciska, Farkas, László, Belagyi, Joseph, Schick, Christoph, Thomson, Christy A., Ananthanarayanan, Vettai S., Alirzayeva, E. G., Baba-Zade, S. N., Sarai, A., Kono, H., Uedaira, H., An, J., Gromiha, Michael M., Oobatake, M., Yutani, Katsuhide, Takano, Kazufumi, Yamagata, Yuriko, Jas, Gouri S., Hofrichter, James, Muñoz, Victor, Eaton, William A., Penoyar, Jonathan, Lo Verde, Philip T., Bódi, Á., Venekei, I., Kardos, J., Gráf, L., Závodszky, P., Szilágyi, András, Závodszky, Péter, Woolfson, D. N., Walshaw, J., Allan, R. D., Funahashi, Jun, Gupta, Savan, Di Nola, A., Mangoni, M., Roccatano, P., Ramachandraiah, Gosu, Chandra, Nagasuma R., Ciani, Barbara, Woolfson, Derek N., Nair, Usha B., Salunke, Dinakar M., Kaur, Kanwal J., Swaminathan, Chittoor P., Surolia, Avadhesha, Pramanik, A., Jörnvall, H., Nygren, P.-Å., Jonasson, P., Ståhl, S., Johansson, B.-L., Kratz, G., Wahren, J., Ekberg, K., Uhlén, M., Jansson, O. T., Uhlén, S., Misselwitz, Rolf, Welfle, Heinz, Welfle, Karin, Höhne, Wolfgang, Kurganov, B. I., Mitskevich, L. G., Fedurkina, N. V., Jarori, Gotam K., Maity, Haripada, Guharay, J., Sengupta, P. K., Sengupta, B., Sridevi, K., Kasturi, S. R., Gupta, S. P., Agarwal, Gunjan, Briehl, Robin W., Kwong, Suzanne, Tyulkova, N A., Ismailova, O. I., Parola, A. H., Yayon, A., Hariharan, C., Pines, D., Pines, E., Zamai, M., Cohen-Luria, R., Woolfeon, D. N., Spooner, G. A., Padya, M. J., Bharadwaj, D. K., Bakshi, Panchan, Jagannathan, N. R., Sharma, U., Srivastava, N., Barthwal, R., Matsuda, Keiko, Nishioka, Takaaki, Go, Nobuhiro, Urata, S., Aita, T., Husimi, Y., Majumder, Mainak, Subirana, Juan A., Malinina, Lucy, Abrescia, Nicola G. A., Aymami, Juan, Coll, Miquel, Eritxa, Ramón, Premraj, B. J., Thenmalarchelvi, R., Gautham, N., Kumar, Satheesh P., Kan, Lou-Sing, Hou, Ming, Lin, Shwu-Bin, Roy, Kanal B., Sana, Tapas, Bruant, N., Flatters, D., Lavery, R., Sklenar, Heinz, Rons, Remo, Lavery, Richard, Thakur, Ashoke Ranjan, Kundu, Sudip, Bandyopadhyay, Debashree, Bhattacharyya, Dhananjay, Majumdar, Rabi, Barceló, F., Portugal, J., Rao, B. 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S., Kombrabail, Mamata H., Aravamudhan, S., Venegas-Cotero, Berenice, Blake, Ivan Ortega, Zhou, Han-qing, Hu, Xiao-jian, Zhang, Zhi-hong, Feng, Hang-fang, Cheng, Wei-ying, Zalyvsky, I. A., Dubitsky, L. O., Vovkanvch, L. S., Savio-Galimberti, E., Ponce-Homos, J. E., Bonazzola, P., Capurro, Claudia, Parisi, Mario, Toriano, Roxana, Thomas, David D., Ready, Laxma G., Jones, Larry R., Tashmukhamedov, B. A., Sagdullaev, B. T., Heitzmann, D., Bleich, M., Warth, R., Ferreira, H. G., Ferreira, K. T. G., Greger, R., Parola, Abraham H., Alfahel, Essa, Zagoory, Orna, Priel, Zvi, Hama-Inaba, H., Ohyama, H., Hayata, I., Choi, K., Haginoya, K., Mori, M., Wang, R., Yukawa, O., Nakajima, T., Joshi, Nanda B., Kannurpatti, Sridhar K., Sinha, Mau, Joshi, Preeti G., Bei, Ling, Hu, Tianhui, Shen, Xun, Knetsch, Menno L. W., Schäfers, Nicole, Sandblom, John, Galvanovskis, Juris, Kovacs, Eugenia, Dinu, Alexandra, Pologea-Moraru, Roxana, Sanghvi, S. H., Jazbinšek, V., Tronteli, Z., Thiel, G., Wübeller, G., Müller, W., Brumen, Milan, Fajmut, Leš, Marhl, Marko, Volotovski, I. D., Sokolovski, S. G., Knight, M. R., Chalyi, Alexander V., Vasilʼev, Alexei N., Sharma, P., Pant, H. C., Sharma, M., Amin, N. D., Albers, R. W., Steinbach, P. J., Barchir, J., Balasubramanyam, M., Gardner, J. P., Condrescu, M., Pilarczyk, Gotz, Greulich, K. O., Monajembashi, Shamci, El-Awadi, A. I., El-Refaei, F. M., Talaat, M. M., Ali, F. M., Zahradniková, Alexandra, Tahradník, Ivan, Pavelková, Jana, Zhorov, Boris S., Ananthanaravanan, Vettai S., Weiss, D. G., Martin, D., Gornik, E., Neu, E., Michailov, Ch. M., Welscher, U., Seidenbusch, W., Jellali, A., Pattnaik, B. R., Hicks, D., Dreyfus, H., Sahel, J., Picaud, S., Forster, V., Wang, Hong-Wei, Sui, Sen-fang, Luther, Pradeep K., Morris, Ed, Barry, John, Squire, John, Sundari, Sivakama C., Balasubramanian, D., Christlet, Hema Thanka T., Veluraia, K., Suresh, Xavier M., Laretta-Garde, V., Krilov, Dubravka, Herak, Janko N., Stojanović, Nataša, Ferrone, Frank A., Ivanova, Maria, Jasuja, Ravi, Mirchev, Rossen, Stopar, David, Wolfs, Cor J. A. M., Hemminga, Marcus A., Spruijt, Ruud B., Arcovito, G., De Spirito, M., Frank, Joachim, Heagle, Amy B., Grassucci, Robert, Penczek, Pawel, Agrawal, Rajendra K., Sharma, Manjuli R., Wagenknecht, Terence, Jeyakumar, Loice H., Fleischer, Sidney, Knupp, Carlo, Squire, John M., Ezra, Eric, Munro, Peter M. G., Kitazawa, Hidefumi, Ichihara, Koji, Itoh, Tomohiko J., Iguchi, Yusuke, Pifat, Greta, Kveder, Marina, Pečar, Slavko, Schara, Milan, Nair, Deepak, Singh, Kavita, Rao, Kanury V. S., Sundaravadivel, B., Jain, Deepti, Kaur, Kanwaljeet, Salunke, D. M., Goel, Manisha, Kovalenko, E. I., Semenkova, G. N., Cherenkevich, S. N., Loganathan, D., Lakshmanan, T., Sriram, D., Srinivasan, S., Lebrón, J. A., Bjorkman, P. J., Ramalingam, T. S., Singh, A. K., Gayatri, T. N., Bisch, Paulo M., Caffarena, Ernesto R., Grigera, Raul J., Fromherz, P., Kiessling, V., Suresh, C. G., Rao, K. N., Khan, M. I., Gaikwad, S. M., Elanthiraiyan, M., Kaliannan, P., Payne, J., Chadha, K., Ambrus, J. L., Nair, M. P. N., Nair, Madhavan P. N., Hewitt, R., Schwartz, S. A., Mahajan, S., Macherel, D., Bourguignon, J., Neuburger, M., Douce, R., Cohen-Addad, C., Faure, M., Ober, R., Sieker, L., Gurumurthy, D. S., Velmurugan, S., Lobo, Z., Phadke, Ratna S., Desai, Prashant, Alieva, D. R., Guseinova, I. M., Zulfugarov, I. S., Aliev, J. A., Ismayilov, M. A., Novruzova, S. N., Savchenko, T. V., Suleimanov, Yu. S., Bartošková, Hana, Nauš, Jan, Ilík, Petr, Kouřil, Roman, Vidyasagar, P. B., Thomas, Sarah, Gaikwad, Jvoti U., Cseh, Z., Mustárdy, L., Garab, G., Simidjiev, I., Rajagopal, S., Várkonyi, Zs., Holzenburg, A., Stoylova, S., Papp, E., Millar, D. P., Bruder, R., Woo, T. T., Genick, U. K., Gerwert, K., Jávorfí, Tamás, Garab, Győző, Naqvi, Razi K., Gaikwad, Jyoti, Kalimullah, Md., Semwal, Manoj, Naus, Man, Ilik, Petr, Kouril, Roman, Horváth, Gábor, Bernard, Gary D., Pomozi, István, Wehner, Rüdiger, Damjanović, Ana, Schulten, Klaus, Ritz, Thorsten, Yandao, Gong, Jushuo, Wang, Nanming, Zhao, Jixiu, Shan, Freiberg, Arvi, Timpmann, Kõu, Woodbury, Neal W., Ruus, Rein, Nemtseva, E. V., Kudryasheva, N. S., Sizykh, A. G., Tikhomirov, A. A., Nesterenko, T. V., Shikhov, V. N., Forti, Giorgio, Furia, Alberto, Finazzi, Giovanni, Barbagallo, Romina Paola, Agalarov, R., Gasanov, R., Iskenderova, S., Nobuhiro, G. O., Osamu, Miyashita, Ramrakhiani, M., Soni, R. K., Yoshida, Masasuke, Akutsu, Hideo, Yagi, Hiromasa, Tozawa, Kacko, Sekino, Nobuaki, Iwabuchi, Tomoyuki, Kaulen, A. 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C., Neagu, Monica, Neagu, Adrian, Janežič, Dušanka, Praprotnik, Matej, Nilsson, Lennart, Mark, Pekka, Fata, La L., Dardenne, Laurent E., Werneck, Araken S., Neto, Marçal de O., Kannan, N., Vishveshwara, S., Veluraja, K., Opitz, David, Balasubramanian, Krishnan, Gute, Brian D., Mills, Denise, Lungeanu, Diana, Mihalas, G. I., Macovievici, G., Gruia, Raluca, Dalcin, B., Cortez-Maghelly, C., Passos, E. P., Ljubisavljevic, M., Blesic, S., Milosevic, S., Stratimirovic, D. J., Bachhawat, Nandita, Mande, Shekhar C., Nandy, A., Nishigaki, Koichi, Saito, Ayumu, Naimuddin, Mohammed, Takaesu, Hirotomo, Ono, Mitsuo, Hirokawa, Takatsugu, Eissa, A. M., Ahmed, Abdalla S., El Gohary, M. I., Nakashima, Hiroshi, Raghava, G. P. S., Kurgalvuk, N., Goryn, O., Gerstman, Bernard S., Kratasyuk, V. A., Esimbekova, E. N., Gritsenko, E. V., Remmel, N. N., Maznyak, O. M., German, A., Tikhonov, A., Tchitchkan, D., Koulchitsky, S., Pashkevich, S., Pletnev, S., Kulchitsky, V., Pesotskaya, Y., Shapiro, Erik M., Borthakur, Arijitt, Dimitrov, Ivan, Leigh, John S., Rizi, Rahim, Reddy, Ravinder, Charagundla, Sridhar, Duvvuri, Umamaheswar, Degaonkar, M., Khubchandani, M., Kumar, Mahesh, Jagannathan, N R., Raghunathan, P., Jayasundar, Rama, Coshic, O., Rath, O. K., Julka, P. K., Iliescu, Karina Roxana, Sajin, Maria, Petcu, Ileana, Moisoi, Nicolcta, Kuzmenko, A. I., Donchenko, G. V., Nikolenko, I. A., Morozova, R. P., Rahman, M. K., Ahmed, M. M., Watanabe, Takehiro, Uretzky, G., Ammar, R., Sharony, R., Rubin, Y., Gilboa, H., Mallick, H. N., Kumar, Mohan V., Begum, Gulnaz M., Degaonkar, Mahaveer N., Govindasamy, S., Kumosani, T. A., Lupusoru, C., Titescu, G., Haulica, I., Stefanescu, I., Iliescu, R., Nastasa, V., Bild, W., Khetawat, Gopal, Nealen, M., Faraday, N., Bray, P. F., Noga, S., Lycholat, E. A., Ananieva, T. V., Kosevich, M V., Stepanyan, S. 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R., Phillip, R., Kumar, Ravindra G., Murata, K., Nagayaka, K., Danev, R., Sugitani, S., Gősch, Michael, Thyberg, P., Földes-Papp, Z., Björk, G., Blom, H., Holm, J., Heino, T., Inagaki, Fuyuhiko, Yokochi, Masashi, Kusunoki, Masami, Matthews, E. K., Pines, J., Chukova, Yu. P., Koltover, Vitaly K., Kang, B. P. S., Bansal, Geetanjali, Bansal, M. P., Singh, U., Singh, Uma, Nakata, Kotoko, Nakano, Tastuya, Kaminuma, Tsuguchika, Kirn, Bonn, Potocnik, Neja, Stare, Vito, Shukla, Latal, Sastry, M. D., Natarajan, V., Devasagayam, T. P. A., Kesavan, P. C., Sayfutdinov, R., Degermendzhy, A. G., Adamovich, V. V., Rogozin, Yu. D., Khetrapal, C. L., Gowda, G. A. Nagana, Ghimire, Kedar Nath, Masaru, Ishida, Fujita, H., Ishiwata, S., Suzuki, M., Kawahara, S., Kirino, Y., Kishimoto, Y., Mori, H., Mishina, M., Ohshima, H., Dukhin, A. S., Goetz, P. J., Shilov, V. N., and Mishra, R. K.
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- 1999
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29. Experimental analysis of turbine‐chamber coupling for wave energy conversion.
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George, Aravind, Anandanarayanan, R., Suchithra, R., Pattnaik, B., Dudhgaonkar, Prasad, Jalihal, Purnima, and Samad, Abdus
- Subjects
HYDRAULIC turbines ,TURBINES ,WAVE energy ,AIR flow ,DAMPING (Mechanics) - Abstract
Summary: A bidirectional axial‐flow impulse turbine installed in an oscillating water column raises the question of damping at different wave conditions. This article reports unsteady performances of such a turbine in an airflow test rig. The rig has a piston‐cylinder arrangement, and the piston, when reciprocating, generates the oscillatory airflow. At a very low wave height (piston stroke length, <0.4 m), the turbine speed is very low. Time series analysis of pressure drop and speed are reported for higher stroke lengths, which shows the rate of increase and decrease in velocity of the turbine. Furthermore, the turbine pressure coefficient and the damping characteristics of the test rig chamber were estimated. Finally, the chamber damping verifies that the turbine‐chamber coupling effect is reciprocal. [ABSTRACT FROM AUTHOR]
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- 2018
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30. P2.11-17 MicroRNAs in Exhaled Breath Condensate and Bronchial Brushings as Biomarkers for Early Diagnosis of Lung Cancer
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Pattnaik, B., Chakraborty, S., Bajpai, P., Agrawal, A., Guleria, R., and Mohan, A.
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- 2018
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31. Differential expression of pro-inflammatory cytokines in endometrial tissue of buffaloes with clinical and sub-clinical endometritis
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Loyi, Tumnyak, Kumar, Harendra, Nandi, S., Mathapati, Basavaraj S., Patra, M.K., and Pattnaik, B.
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- 2013
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32. Living donor liver transplantation for alcoholic liver disease; does abstinence correlate with recidivism?
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Pattnaik, B., Sinha, P., Sasturkar, S., Mohapatra, N., and Pamecha, V.
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- 2018
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33. Comparative therapeutic efficacy of levofloxacin, ornidazole and alpha tocopherol combination with prostaglandin F2a on IL-6 and IL-10 transcript level in longstanding cases of endometritis in crossbreed Jersey cows.
- Author
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Mishra, S., Sahu, S. K., Panigrahi, S., Biswal, S. S., Mishra, S. R., Ranjan, R., Mohanty, D. N., Pattnaik, B., and Das, S.
- Subjects
THERAPEUTIC use of vitamin E ,INTERLEUKIN-10 ,TREATMENT effectiveness ,PROSTAGLANDINS ,ENDOMETRITIS ,JERSEY cattle - Abstract
This study compared the therapeutic efficacy of levofloxacin, ornidazole and alpha tocopherol combination and prostaglandin F2a (PGF2a) in longstanding cases of endometritis and evaluated their impact on Interleukin-6 (IL-6) and Interleukin-10 (IL-10) transcript level in peripheral blood leukocytes. Eighteen endometritic crossbred Jersey cows were randomly allotted to three groups (six in each) viz. Group I (levofloxacin combo treatment I/U), group II (PGF2a treatment I/M), group III (no treatment, control), and group IV (six non-endometritic healthy cyclic) was taken for comparison study. The clinical efficacy was assessed by haematological study (TLC: Total leukocyte count; DC: Differential count), polymorphonuclear leukocytes (PMN) count in uterine cytology and relative mRNA expression of IL-6 and IL-10 in peripheral blood leukocytes before and after treatment with respect to conception rate following single and second inseminations. Group I and II registered significant increase in TLC and neutrophil count. PMN cytology was increased two and three fold in group I and II, respectively. The IL-6 transcript level was increased by 2.5 and 4.6 fold while that of IL-10 increased by 3.7 and 5.2 fold in group I and II, respectively. Conception rate across group I to IV following single insemination was found to be 66.67%, 50%, 16.67%, and 83.33% and their corresponding values following second insemination were 66.67%, 83.33%, 16.67%, and 83.33%, respectively. Thus, the administration of levofloxacin combo and PGF2a might have better conception rate following first and second insemination, respectively. Our study also reveals that PGF2a could register better clearance of bacteria through stronger PMN cell and cytokine activity in post-treatment period. [ABSTRACT FROM AUTHOR]
- Published
- 2018
34. Dynamics of widespread foot‐and‐mouth disease virus serotypes A, O and Asia‐1 in southern Asia: A Bayesian phylogenetic perspective.
- Author
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Brito, B. P., Mohapatra, J. K., Subramaniam, S., Pattnaik, B., Rodriguez, L. L., Moore, B. R., and Perez, A. M.
- Subjects
SEROTYPES ,FOOT & mouth disease virus ,PHYLOGENY ,VIRAL genes ,GENETIC code - Abstract
Summary: Foot‐and‐mouth disease (FMD) is, arguably, the animal disease with the most devastating global economic impact owing in part, to the severe trade restrictions imposed upon affected countries and regions. South Asia is one of the regions where widespread lineages of the FMDV virus (FMDV) have emerged. Here, we performed an integrative phylogenetic analysis of all FMDV serotypes (A, O and Asia‐1) circulating in southern Asia, including viral sequences collected until 2013. Our results describe the occurrence of FMD caused by different serotypes and lineages, focusing in the cycles where a specific lineage predominates within a region for a protracted period and then are rapidly or progressively replaced by an emergent or re‐emergent strain that is introduced from an adjacent region. Transmission between the two main regions in southern Asia (the Indian subcontinent and the region comprised by Afghanistan, Iran and Pakistan) has been limited. Results of time divergence estimation of lineages that currently circulate in this region indicate that the most recent common ancestor of endemic lineages are: 1992 [1989–1995] for lineage O/PanAsia; 1997 [1995–1999] for PanAsia2; 2001 [1998–2004] for O/Ind2001; 2001 [2000–2002] for A/Iran‐05; 1990 [1988–1991] for A/G‐18 (G‐VII); 2003 [2000–2006] for Asia‐1 Sindh08 and 2002 [1999–2004] for Asia‐1 G‐VIII. We estimated the mean of the overall substitution rate of the VP1 coding region (substitution/site/year) for serotype O (5.95 × 10
−3 ), serotype A (1.19 × 10−2 ) and serotype Asia‐1 (3.08 × 10−3 ). The potential factors driving the lineage turnover are discussed. Our results provide insights into the ecological and evolutionary factors driving the emergence of FMDV. [ABSTRACT FROM AUTHOR]- Published
- 2018
- Full Text
- View/download PDF
35. Investigation of foot-and mouth disease outbreak in a pig farm at Kollam district of Kerala, India.
- Author
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Rout, M., Subramaniam, S., Mohapatra, J. K., Dash, B. B., and Pattnaik, B.
- Subjects
FOOT & mouth disease ,SWINE farms ,SWINE diseases ,ENZYME-linked immunosorbent assay ,REVERSE transcriptase polymerase chain reaction - Abstract
The present paper describes the investigation of foot-and-mouth disease (FMD) outbreak in a private pig farm at Kotty in Kollam district of Kerala during October 2013. During the clinical phase, severe vesicular lesions on snout and skin around the coronary bands were observed in pigs. A total of 48 serum samples and 12 clinical samples (ruptured snout epithelia) were collected. All serum samples were subjected to indirect 3AB nonstructural protein (NSP) ELISA and liquid phase blocking (LPB) ELISA. In 3AB NSP ELISA, all serum samples were found positive for NSP antibodies indicating infection. In LPB ELISA, 42 of 48 (87.5%) pigs were found to have protective log
10 antibody titre of ≥1.8 against FMD virus serotypes O, A and Asia 1. All the clinical materials were found positive for serotype O in antigen detection ELISA as well as in multiplex reverse transcription-polymerase chain reaction (mRT-PCR). In VP1 region-based phylogenetic analysis, the serotype O isolates causing the outbreak were found to conglomerate within Ind2001 lineage. Pigs infected with FMD may pose rigorous threat to other susceptible domestic livestock as they exhale enormous quantity of virus. As a consequence, they should be included under prophylactic vaccination and surveillance programmes ongoing in the country. [ABSTRACT FROM AUTHOR]- Published
- 2018
- Full Text
- View/download PDF
36. Foot‐and‐mouth disease virus transmission dynamics and persistence in a herd of vaccinated dairy cattle in India.
- Author
-
Hayer, S. S., VanderWaal, K., Ranjan, R., Biswal, J. K., Subramaniam, S., Mohapatra, J. K., Sharma, G. K., Rout, M., Dash, B. B., Das, B., Prusty, B. R., Sharma, A. K., Stenfeldt, C., Perez, A., Delgado, A. H., Sharma, M. K., Rodriguez, L. L., Pattnaik, B., and Arzt, J.
- Subjects
FOOT & mouth disease ,FOOT & mouth disease vaccines ,FOOT & mouth disease epidemiology ,MEDICAL economics ,EPIDEMIOLOGY ,CATTLE - Abstract
Summary: Foot‐and‐mouth disease (FMD) is an important transboundary disease with substantial economic impacts. Although between‐herd transmission of the disease has been well studied, studies focusing on within‐herd transmission using farm‐level outbreak data are rare. The aim of this study was to estimate parameters associated with within‐herd transmission, host physiological factors and FMD virus (FMDV) persistence using data collected from an outbreak that occurred at a large, organized dairy farm in India. Of 1,836 regularly vaccinated, adult dairy cattle, 222 had clinical signs of FMD over a 39‐day period. Assuming homogenous mixing, a frequency‐dependent compartmental model of disease transmission was built. The transmission coefficient and basic reproductive number were estimated to be between 16.2–18.4 and 67–88, respectively. Non‐pregnant animals were more likely to manifest clinical signs of FMD as compared to pregnant cattle. Based on oropharyngeal fluid (probang) sampling and FMDV‐specific RT‐PCR, four of 36 longitudinally sampled animals (14%) were persistently infected carriers 10.5 months post‐outbreak. There was no statistical difference between subclinical and clinically infected animals in the duration of the carrier state. However, prevalence of NSP‐ELISA antibodies differed significantly between subclinical and clinically infected animals 12 months after the outbreak with 83% seroprevalence amongst clinically infected cattle compared to 69% of subclinical animals. This study further elucidates within‐herd FMD transmission dynamics during the acute‐phase and characterizes duration of FMDV persistence and seroprevalence of FMD under natural conditions in an endemic setting. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
37. Molecular epidemiologic investigation of foot-and-mouth disease in pig population of India.
- Author
-
Rout, M., Subramaniam, S., Mohapatra, J. K., and Pattnaik, B.
- Subjects
FOOT & mouth disease ,MOLECULAR epidemiology ,CATTLE ,SEROTYPES ,ENZYME-linked immunosorbent assay ,SWINE - Abstract
Foot-and-mouth disease (FMD) is a highly contagious and globally significant viral disease principally of cloven-hoofed livestock species. The present study describes the results of molecular epidemiologic investigation of FMD in pigs across various states of India between 2008 and 2014. During this period, a total of 37 clinical epithelial samples (vesicle/foot/snout epithelium) of FMD-suspected pigs were tested in a serotype differentiating antigen detection ELISA and samples found negative were further subjected to multiplex reverse transcription-polymerase chain reaction (mRT-PCR). A total of 29 (78.37%) samples were found positive for serotype O in antigen detection ELISA and 8 ELISA-negative samples were subsequently found positive for serotype O in mRT-PCR. The VP1 region-based phylogenetic analysis demonstrated the involvement of O/ME-SA/Ind2001 lineage in the outbreaks. The pig isolates clustered with the contemporary virus isolates collected from bovine indicating a close genetic relationship and therefore signifying inter-species transmission during the outbreaks. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
38. Phylogenetic characterization of foot-and-mouth disease virus recovered from mithuns and yaks in India.
- Author
-
Rout, M., Subramaniam, S., Mohapatra, J. K., Sanyal, A., Dash, B. B., and Pattnaik, B.
- Subjects
PHYLOGENY ,FOOT & mouth disease ,ENZYME-linked immunosorbent assay ,POLYMERASE chain reaction ,TRANSCRIPTION factors - Abstract
The yak and mithun husbandry in India is confronted with several challenges including the prevalence of foot-and-mouth disease (FMD). The present study was initiated to investigate FMD outbreaks in semi-domesticated mithun and yak population in various parts of India. A total of 64 clinical samples (vesicle/tongue/foot epithelium/fluid) from mithun and 6 from yak were collected from suspected FMD outbreaks during 2008-2013. Supernatants of the homogenized clinical samples were tested in a serotype discriminating antigen detection ELISA and ELISA-negative samples were further subjected to multiplex reverse transcription-polymerase chain reaction (mRT-PCR). A total of 45 mithun samples and only 1 yak sample were found positive for serotype O in antigen detection ELISA. A total of 12 ELISA-negative samples from mithun and 4 from yak were later on found positive for serotype O in mRT-PCR. The phylogenetic analysis based on VP1 genome indicated the involvement of both O/ME-SA/PanAsia and O/ME-SA/Ind2001 lineages of serotype O in those outbreaks. These viruses were genetically similar to those contemporary virus isolates responsible for FMD in domestic livestock indicating a situation of virus sharing among different species of domestic and semi-domestic animals. Thus, mithuns and yaks should be synchronously considered and targeted along with cattle for the effective control of the disease in the country. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
39. Experimental evidence for competitive growth advantage of genotype VII over VI: Implications for foot-and-mouth disease virus serotype A genotype turnover in nature
- Author
-
Mohapatra, J.K., Subramaniam, S., Singh, N.K., Sanyal, A., and Pattnaik, B.
- Published
- 2012
- Full Text
- View/download PDF
40. Herd Immunity Against Foot-and-Mouth Disease Under Different Vaccination Practices in India.
- Author
-
Sharma, G. K., Mahajan, S., Matura, R., Biswal, J. K., Ranjan, R., Subramaniam, S., Misri, J., Bambal, R. G., and Pattnaik, B.
- Subjects
HERD immunity ,VACCINATION ,FOOT & mouth disease ,DISEASE progression ,ANALYTICAL mechanics - Abstract
A systematic vaccination programme is ongoing in India to control the three prevailing serotypes (A, O, Asia1) of foot-and-mouth disease ( FMD) virus. Under the programme, more than 120 million bovine (term bovine applicable to both cattle and buffalo in this study) population of 221 of the 666 districts in the country are being bi-annually vaccinated with trivalent vaccine since 2010. Although clinical disease has reduced in these districts because of the systematic vaccinations, an abrupt increase in the number of FMD cases was recorded in 2013. Hence, a longitudinal field study was conducted in the year 2014 to estimate the serological herd immunity level in bovines, the impact of systematic vaccinations and field efficacy of the vaccines used. Serum samples ( n = 115 963) collected from 295 districts of the 18 states of the country were analysed to estimate antibody titres against structural proteins of the three serotypes. The efficacy of the vaccine was demonstrated in the control group (group-D) where animals of the group were identified by ear tags for the purpose of repeated sampling after vaccination. Progressive building of the herd immunity in the field after systematic vaccination was demonstrated. The mean antibody titre against the serotypes O, A and Asia1 was estimated as log
10 1.93 (95% CI 1.92-1.93), 2.02 (2.02-2.02) and 2.02 (2.02-2.02), respectively, in the states covered under the control programme. However, in other states herd immunity was significantly low [mean titre log10 1.68 (95% CI 1.67-1.69), 1.77 (1.76-1.78) and 1.85 (1.84-1.86) against the three serotypes]. Inverse relationship between the herd immunity and FMD incidences was observed the states following different vaccination practices. The study helped in demarcation of FMD risk zones in the country with low herd immunity. Estimation of herd immunity kinetics in the field helped in refining the vaccination schedule under the control programme. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
41. Farm Community Impacts of Foot-and- Mouth Disease Outbreaks in Cattle and Buffaloes in Karnataka State, India.
- Author
-
Govindaraj, G., Ganeshkumar, B., Nethrayini, K. R., Shalini, R., Balamurugan, V., Pattnaik, B., and Rahman, H.
- Subjects
FOOT & mouth disease ,MILK yield ,SENSITIVITY analysis ,SOCIAL impact ,PSYCHOLOGICAL stress - Abstract
This study was conducted to assess the impact of Foot-and-mouth Disease ( FMD) outbreak in cattle and buffaloes on farming community in Kolar district, Karnataka state, India. Primary data were collected using pre-tested schedule from 178 sample farms using multistage random cluster sample technique. The results revealed that 78% of surveyed villages were affected with FMD. The FMD incidence risk was high across the herd sizes, whereas the mortality risk was high in small herds. In indigenous cattle, the highest loss due to FMD was distress sale (208 USD) followed by other losses, whereas, in Crossbred cattle, the highest loss was mortality loss (515 USD) followed by distress sale (490 USD), milk yield loss (327 USD), treatment cost (38 USD) and extra labour engagement expenses for nursing of FMD-affected bovines (30 USD). In local and upgraded buffaloes, the mean total loss per affected animal was 440 USD and 513 USD, respectively. A very high variability in the loss per animal was observed across the type of losses in the Crossbred cattle, and it may be due to differences in age of the FMD-infected animal, value of the animal, milking stage, lactation levels, herd sizes and labour engagement levels, etc. In local and upgraded buffaloes, the mean total loss per animal was 639 USD and 1008 USD, respectively. The sensitivity analysis for 5% change in price revealed that the mean total loss per animal was positively correlated with price. Further, the social impact elicitation revealed that majority of the livestock owners perceived FMD had caused permanent asset loss, which in turn increased psychological stress of the family. The estimated losses and social impact due to FMD signify the importance of the intervention to control the disease and thus socio-economic gain to the farmer and society at large. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
42. Outbreaks of Foot-and-Mouth Disease in Libya and Saudi Arabia During 2013 Due to an Exotic O/ ME- SA/Ind-2001 Lineage Virus.
- Author
-
Knowles, N. J., Bachanek ‐ Bankowska, K., Wadsworth, J., Mioulet, V., Valdazo ‐ González, B., Eldaghayes, I. M., Dayhum, A. S., Kammon, A. M., Sharif, M. A., Waight, S., Shamia, A. M., Tenzin, S., Wernery, U., Grazioli, S., Brocchi, E., Subramaniam, S., Pattnaik, B., and King, D. P.
- Subjects
FOOT & mouth disease ,DISEASE outbreaks ,PHYLOGENY - Abstract
Foot-and-mouth disease viruses are often restricted to specific geographical regions and spread to new areas may lead to significant epidemics. Phylogenetic analysis of sequences of the VP1 genome region of recent outbreak viruses from Libya and Saudi Arabia has revealed a lineage, O-Ind-2001, normally found in the Indian subcontinent. This paper describes the characterization of field viruses collected from these cases and provides information about a new real-time RT- PCR assay that can be used to detect viruses from this lineage and discriminate them from other endemic FMD viruses that are co-circulating in North Africa and western Eurasia. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
43. Isolation and pathotyping of H9N2 avian influenza viruses in Indian poultry
- Author
-
Nagarajan, S., Rajukumar, K., Tosh, C., Ramaswamy, V., Purohit, K., Saxena, G., Behera, P., Pattnaik, B., Pradhan, H.K., and Dubey, S.C.
- Published
- 2009
- Full Text
- View/download PDF
44. Development of naïve phage display VHH libraries from Indian camel.
- Author
-
DASH, L., SUBRAMANIAM, S., KHULAPE, S. A., PRUSTY, B. R., PARGAI, K., NARNAWARE, S. D., PATIL, N. V., and PATTNAIK, B.
- Abstract
The present study describes the construction of naïve camelid VHH single pot library from lymphocytes of non-immunized Camelus dromedarius. RNA extracted from 6 healthy female camels was pooled together and used for construction of library in phagentid vector. The VHH inserts were found in 50-70% of the phagemid vector (pMECS vector) cloned in Escherichia coli and the size of the libraries was estimated to be around 10
5 -107 cfu. Sequence analysis of VHHs revealed variations in the length of complementary determining regions and amino acid usage resulting in a variety of different paratopes. Further expression of VHH rescued from the library was optimized in prokaryotic system using pET32 expression system. Functional antibodies generated from this naïve library will be explored for affinity against various antigens in further studies. [ABSTRACT FROM AUTHOR]- Published
- 2016
- Full Text
- View/download PDF
45. Sequence based typing for BoLA-DQA1 alleles in Indian zebu and its crossbred populations.
- Author
-
VANDRE, R. K., SHARMA, A. K., GOWANE, G. R., SANKAR, M., SANYAL, A., and PATTNAIK, B.
- Abstract
Polymorphism in the major histocompatibility complex of the bovine, which is referred to as bovine leukocyte antigens (BoLAs), was intensively investigated for identifying marker(s) for bovine diseases and immunological traits. This approach requires identifying and documenting the allelic diversity of BoLA among different breeds of cattle using PCR-SBT technique. In this study, we could standardise the most useful approach of unravelling polymorphism in DQA1 exon 2 of cattle using PCR-sequence based typing (SBT). We could identify 16 different DQA1 alleles in 43 zebu and crossbred cattle, out of which 26 were homozygous and 17 were heterozygous. PCRSBT has proved to be the most useful method for exploring the allelic polymorphism in DQA1 gene in zebu and its crossbred cattle in our study. Further use of this technique is equally appropriate for all kinds of traits i.e. production, reproduction and growth type of traits and beneficial for establishing new breeding objectives. [ABSTRACT FROM AUTHOR]
- Published
- 2016
46. Diagnostic potential of recombinant scFv antibodies generated against hemagglutinin protein of influenza A virus.
- Author
-
Rajput, Roopali, Sharma, Gaurav, Rawat, Varsha, Gautam, Anju, Kumar, Binod, Pattnaik, B., Pradhan, H. K., Khanna, Madhu, Sethi, Dhruv, and Kavanagh, Owen
- Subjects
INFLUENZA A virus ,HEMAGGLUTININ ,SOCIOECONOMICS ,DIAGNOSIS - Abstract
Human influenza A viruses have been the cause of enormous socio-economic losses worldwide. In order to combat such a notorious pathogen, hemagglutinin protein (HA) has been a preferred target for generation of neutralizing-antibodies as potent therapeutic/ diagnostic agents. In the present study, recombinant anti-HA single chain variable fragment antibodies were constructed using the phage-display technology to aid in diagnosis and treatment of human influenza A virus infections. Spleen cells of mice hyper-immunized with A/New Caledonia/20/99 (H1N1) virus were used as the source for recombinant antibody (rAb) production. The antigen-binding phages were quantified after six rounds of bio-panning against A/New Caledonia/20/99 (H1N1), A/California/07/2009 (H1N1)-like, or A/Udorn/307/72(H3N2) viruses. The maximum phage yield was for the A/New Caledonia/20/99 (H1N1), however, considerable cross-reactivity was observed for the other virus strains as well. The HA-specific polyclonal rAb preparation was subjected to selection of single clones for identification of high reactive relatively conserved epitopes. The high-affinity rAbs were tested against certain known conserved HA epitopes by peptide ELISA. Three recombinant mAbs showed reactivity with both the H1N1 strains and one (C5) showed binding with all the three viral strains. The C5 antibody was thus used for development of an ELISA test for diagnosis of influenza virus infection. Based on the sample size in the current analysis, the ELISA test demonstrated 83.9% sensitivity and 100% specificity. Thus, the ELISA, developed in our study, may prove as a cheaper alternative to the presently used real time RT-PCR test for detection of human influenza A viruses in clinical specimens, which will be beneficial, especially in the developing countries. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
47. Comparison of stabilisers for development of a lyophilised multiplex reverse-transcription PCR mixture for rapid detection of foot and mouth disease virus serotypes.
- Author
-
Sharma, G. K., Mahajan, S., Das, B., Ranjan, R., Kanani, A., Sanyal, A., and Pattnaik, B.
- Published
- 2014
- Full Text
- View/download PDF
48. Foot-and-mouth disease in wildlife population of India.
- Author
-
Rout, M., Subramaniam, S., Das, B., Mohapatra, J. K., Dash, B. B., Sanyal, A., and Pattnaik, B.
- Subjects
FOOT & mouth disease ,ANIMAL species ,ANIMAL populations ,ENZYME-linked immunosorbent assay ,CATTLE - Abstract
A total of 41 clinical samples (vesicle/tongue/foot/nasal epithelium) from Indian gaur, deer, spotted deer, nilgai, chowsinga, bison, black buck, elephant, sambar deer were collected in 50% phosphate buffered saline/glycerol medium (pH-7.5) during suspected FMD outbreaks. Supernatants of homogenized clinical samples were used in a serotype differentiating antigen detection ELISA and samples found negative were further subjected to multiplex PCR (mPCR). A total of 3/11 (27.2%) samples from Indian gaur, 2/7 (28.5%) chital deer, 5/5 (100%) nilgai, 2/2 (100%) black buck were found positive for serotype O in antigen detection ELISA. A total of 3 ELISA-negative samples from spotted deer, 2 from bison and 2 from sambar deer were found positive for serotype O in mPCR. The VP1 region-based phylogenetic analysis indicated the involvement of both O/ME-SA/Ind2001 and PanAsia lineage of serotype O in the outbreaks. The wildlife species infected with FMD may pose further threat to the surrounding domestic livestock. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
49. Trend of association of BoLA-DQA1 alleles with FMDV vaccine elicited immune response in crossbred cattle.
- Author
-
VANDRE, R. K., SHARMA, A. K., GOWANE, G. R., SANKAR, M., SANYAL, A., BISHT, POONAM, and PATTNAIK, B.
- Abstract
The article discusses a study which investigated the association of DQA1 alleles with foot and mouth disease virus (FMDV) vaccine in a closed population of crossbred cattle. Topics covered include FMDV being the causative agent of foot and mouth disease among cloven-hoofed livestock, differentiation of infected and vaccinated animals, and the use of liquid phase blocking enzyme linked immunoassay for detection of antibody against FMDV vaccine.
- Published
- 2014
- Full Text
- View/download PDF
50. The Expression of IL6 and 21 in Crossbred Calves Upregulated by Inactivated Trivalent FMD Vaccine.
- Author
-
Gowane, G.R., Sharma, A.K., Sankar, M., Narayanan, K., Bisht, Punam, Subramaniam, S., and Pattnaik, B.
- Subjects
GENE expression in mammals ,INTERLEUKIN-6 ,INTERLEUKIN-21 ,FOOT & mouth disease vaccines ,POLYMERASE chain reaction ,ENZYME-linked immunosorbent assay - Abstract
Foot and mouth disease (FMD) is an economically important disease and a whole-virus inactivated trivalent virus vaccine is the mainstay for controlling the disease in India. The protective humoral immune response to FMD vaccination is a complex, but, tightly regulated process mediated by the interplay of interleukins (IL). Based on the specific role of IL6 and 21 in adaptive immune response, we hypothesized that inactivated trivalent FMD vaccine would stimulate IL6 and 21 expression in the circulating lymphocytes. The expressions of IL6 and 21 were assayed on 0, 28, 60, 90, and 120 d post-vaccination (DPV) by quantitative PCR (qPCR) with simultaneous assessment of FMDV antibody titer by liquid phase blocking ELISA. The results revealed that the peak expression of IL6 and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV. As IL21 is the final effector of antibody production as compared to IL6, we investigated the expression of IL21 in calves that had protective titer (>1.8) with the unprotected group (<1.8). Expression of IL21 on 28 DPV was numerically higher in the protected than that of the unprotected group of calves. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
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