139 results on '"Peñarrocha-Diago, María"'
Search Results
2. Healing of 295 Endodontic Microsurgery Cases After Long-Term (5-9 Years) Versus Middle-Term (1-4 Years) Follow-up
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Pallarés-Serrano, Antonio, Glera-Suarez, Pablo, Tarazona-Alvarez, Beatriz, Peñarrocha-Oltra, David, Peñarrocha-Diago, Miguel, and Peñarrocha-Diago, María
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- 2022
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3. Is Healing of Periapical Surgery Influenced by Endoscopic Findings Detected on the Cut Root Surface?
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Glera-Suárez, Pablo, Pallarés-Serrano, Antonio, Penarrocha-Oltra, David, Penarrocha-Diago, Miguel, and Penarrocha-Diago, María
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- 2022
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4. Prognostic Factors after Endodontic Microsurgery: A Retrospective Study of 111 Cases with 5 to 9 Years of Follow-up
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Pallarés-Serrano, Antonio, Glera-Suarez, Pablo, Tarazona-Alvarez, Beatriz, Peñarrocha-Diago, María, Peñarrocha-Diago, Miguel, and Peñarrocha-Oltra, David
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- 2021
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5. Influence of Splint Support on the Precision of Static Totally Guided Dental Implant Surgery: A Systematic Review and Network Meta-analysis.
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Carlos Balaguer-Martí, José, Canet-López, Álvaro, Peñarrocha-Diago, Miguel, Romeo-Rubio, Marta, Peñarrocha-Diago, María, and García-Mira, Berta
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DENTAL implants ,ONLINE information services ,MEDICAL databases ,COMPUTER-assisted surgery ,META-analysis ,MEDICAL information storage & retrieval systems ,CONFIDENCE intervals ,SYSTEMATIC reviews ,HEALTH outcome assessment ,ACCURACY ,SPLINTS (Surgery) ,REGRESSION analysis ,TISSUES ,DESCRIPTIVE statistics ,MEDLINE ,RESEARCH bias ,BIOMECHANICS - Abstract
Purpose: To assess the accuracy of totally guided implant placement with static surgical splints in relation to the different types of supporting tissues (tooth, mucosa, or bone). Materials and Methods: This review was carried out following the PRISMA guidelines. An electronic search was done of the MEDLINE (PubMed), Embase, and Cochrane Library databases, without publication year or language restrictions. Results: The literature search yielded a total of 877 articles; 18 were included in the qualitative synthesis, and 16 of these articles were included in the quantitative analysis. The included studies presented a high risk of bias, except for one randomized clinical trial. The strength of the recommendations is therefore weak. In the angular deviation treatment, statistically significant differences were observed in the accuracy of the implants with tooth vs bone support: Bone support yielded 1.31 degrees greater deviation vs tooth support (SD = 0.43; 95% CI: 0.47, 2.15, P = .002). No significant differences were observed in the linear deviations. Conclusion: Tooth support proved to be significantly more precise than bone support splints. There were no differences referring to horizontal coronal deviation, horizontal apical deviation, or vertical deviation according to the type of splint support used. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Hemostatic Agents in Endodontic Surgery: A Randomized Controlled Pilot Study of Polytetrafluoroethylene Strips as an Adjunct to Epinephrine Impregnated Gauze Versus Aluminum Chloride
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Peñarrocha-Oltra, David, Soto-Peñaloza, David, Peñarrocha-Diago, Miguel, Cervera-Ballester, Juan, von Arx, Thomas, Dr. med. dent., and Peñarrocha-Diago, María
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- 2019
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7. Aluminum Chloride versus Electrocauterization in Periapical Surgery: A Randomized Controlled Trial
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Peñarrocha-Oltra, David, Menéndez-Nieto, Isabel, Cervera-Ballester, Juan, Maestre-Ferrín, Laura, Peñarrocha-Diago, Miguel, and Peñarrocha-Diago, María
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- 2019
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8. Diagnosis and indications for the extraction of third molars - The SECIB clinical practice guideline.
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Sánchez-Garcés, Ángeles, Toledano-Serrabona, Jorge, Camps-Font, Octavi, Peñarrocha-Diago, María, Sánchez-Torres, Alba, Sanmartí-Garcia, Gemma, Vegas-Bustamante, Erika, Figueiredo, Rui, Valmaseda-Castellón, Eduard, and Gay-Escoda, Cosme
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MEDICAL personnel ,THIRD molars ,ORAL surgery ,CLINICAL indications ,OPERATIVE surgery - Abstract
Background: The removal of third molars (3Ms) is the most frequent surgical procedure in the field of Oral Surgery. As a result, the Spanish Society of Oral Surgery (SECIB) aims to create a Clinical Practice Guideline (CPG) that offers evidence-based recommendations for optimal clinical practice. Specifically, the CPG will focus on providing guidance regarding the indications and criteria for clinical and radiological diagnosis of patients with 3Ms. Material and Methods: This CPG was developed by the SECIB, following the methodological guidelines described in the methodological manual for the “Development of Clinical Practice Guidelines in the National Health System”. Several PICO questions related to the diagnosis and indications for the extraction of 3Ms were formulated. The leading experts carried out the evaluation of the evidence and the formulation of specific recommendations. Results: A total of 17 PICO questions were evaluated, addressing the indications, prognosis, diagnosis, and costbenefit relationship of 3M extraction. Conclusions: The present Clinical Practice Guideline provides evidence-based recommendations on the diagnosis and indications for 3M extraction. These evidence-based recommendations can assist healthcare professionals and the general population in making informed decisions regarding the management of 3Ms. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Influence of Hemostatic Agents in the Prognosis of Periapical Surgery: A Randomized Study of Epinephrine versus Aluminum Chloride
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Peñarrocha-Diago, María, Menéndez-Nieto, Isabel, Cervera-Ballester, Juan, Maestre-Ferrín, Laura, Blaya-Tárraga, Juan Antonio, and Peñarrocha-Oltra, David
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- 2018
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10. Systematic review of surgical regenerative treatment for apicomarginal lesions in periapical surgery.
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Attar-Attar, Lina, Carlos Bernabeu-Mira, Juan, Cervera-Ballester, Juan, Peñarrocha-Diago, Miguel, and Peñarrocha-Diago, María
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CEMENTUM ,GUIDED tissue regeneration ,REGENERATION (Biology) ,AMELOBLASTS ,PLATELET-rich plasma ,BONE growth ,SURGERY - Abstract
Background: Apicomarginal lesions affect the root apex and root surface concurrently and reduce the success rate in periapical surgery. The purpose of this systematic review was to analyze the published literature on the surgical treatment of apicomarginal lesions in periapical surgery. Material and Methods: A systematic review was conducted on PRISMA statement. Three data bases (PubMed-Medline, Scopus, and Embase) were searched up to March 2023. The inclusion criteria for this systematic review encompass studies pertaining to apicomarginal lesions and their surgical treatment, both preclinical and clinical in nature (including randomized trials, prospective, and retrospective observational trials), without any language or time limitations. Exclusion criteria encompass studies with duplicated population data, no description of the surgical treatment or regenerative material. Different tools for the assessment of bias were applied for each study design Results: A total of 155 articles were searched and 10 were included. Studies on teeth with apicomarginal lesions undergoing periapical surgery showed a high success rate when regenerative techniques were used, resulting in reduced probing depth, increased bone formation on the root surface, increased root cementum formation, and reduced healing by junctional epithelium. Guided tissue regeneration, platelet-rich plasma or fibrin, and enamel matrix derivatives have emerged as alternative treatments offering favorable outcomes. Conclusions: The use of regenerative materials in periapical surgery could improve the prognosis of apicomarginal lesions. Future research in this field should aim to standardize classification and healing criteria to enhance comparability across studies and provide more conclusive evidence for optimal treatment approaches. [ABSTRACT FROM AUTHOR]
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- 2024
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11. A combined digital and stereophotogrammetric technique for rehabilitation with immediate loading of complete-arch, implant-supported prostheses: A randomized controlled pilot clinical trial
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Peñarrocha-Diago, María, Balaguer-Martí, José Carlos, Peñarrocha-Oltra, David, Balaguer-Martínez, José Francisco, Peñarrocha-Diago, Miguel, and Agustín-Panadero, Rubén
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- 2017
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12. Comparison of patient‐centered outcomes measures between low‐speed drilling without irrigation and high‐speed drilling with irrigation: A randomized clinical trial.
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Bernabeu‐Mira, Juan Carlos, Peñarrocha‐Diago, Miguel, Peñarrocha‐Diago, María, Romero‐Gavilán, Francisco, Camacho‐Alonso, Fabio, and Peñarrocha‐Oltra, David
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CLINICAL trials ,IRRIGATION (Medicine) ,PATIENT satisfaction ,POSTOPERATIVE pain ,VISUAL analog scale - Abstract
Objective: To compare patient satisfaction during surgery, postoperative pain and inflammation and quality of life between high‐speed drilling with irrigation and low‐speed drilling without irrigation for implant bed preparation. Materials and Methods: Sixty‐six posterior single edentulous patients were included in a randomized controlled clinical trial. Implant beds were created using high‐speed drilling with irrigation (control group) or low‐speed drilling without irrigation (test group). Patient satisfaction during surgery (in relation to drilling‐time perception, vibration, pressure, noise, comfort, and drowning sensation) and postoperative pain and inflammation were evaluated using a 100‐mm visual analogue scale (VAS)‐based questionnaire. Quality of life was analyzed with a Likert scale (in relation to mouth opening, chewing, speaking, sleeping, daily routine, and job). The follow‐up period was 7 days. Results: Patient satisfaction in relation to drilling‐time perception, vibration, pressure, and noise did not show statistically significant differences (p >.05). The highest scores of drowning sensation (p <.05) were correlated (moderate correlation (r =.57)) with lowest scores of comfort (p <.005). Both postoperative pain and inflammation means were significantly higher in the control group than in the test group. No significant differences in quality of life were observed during the postoperative period (p >.05). Conclusion: Low‐speed drilling without irrigation for single implant site preparation was more comfortable for patients than high‐speed drilling with irrigation, due to the correlation between important drowning sensation and low perceived comfort. Postoperative pain and inflammation were lower for low‐speed drilling without irrigation. Further studies are needed to validate or refute these results. [ABSTRACT FROM AUTHOR]
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- 2024
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13. Clinical practice guideline of the spanish society of oral surgery for oral surgery in patients with coagulation disorders.
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Valenzuela-Mencia, Javier, Serrera-Figallo, María Ángeles, Torres-Lagares, Daniel, Machuca-Portillo, Guillermo, Sánchez-Fernández, Elena, Valmaseda-Castellón, Eduard, Peñarrocha-Diago, María, Fernández-Mosteirín, Nuria, Manuel Somoza-Martin, José, Pérez-Jardón, Alba, Micaela Chamorro-Petronacci, Cintia, and García-García, Abel
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ORAL surgery ,BLOOD coagulation disorders ,DENTAL extraction ,GENERAL practitioners ,BLOOD coagulation ,ORAL medication ,ARACHNOID cysts - Abstract
Background: The number of patients treated with coagulation disorders, and more specifically with anticoagulant therapy, has increased worldwide in recent years due to increased life expectancy in developed countries. The protocols for managing this type of patient in oral surgery has varied over recent years, especially after the appearance of new direct-acting oral anticoagulants (DOACs). The assessment of risk of bleeding in this type of patient when undergoing a surgical procedure continues to be a controversial issue for patients, dentists and general practitioners. The objective of this document is to offer recommendations, based on evidence, for decision making for patients with coagulopathies who require dental surgical intervention. Material and Methods: Based on the indications of the "Preparation of Clinical Practice guidelines in the National Health System. Methodological manual", we gathered a group of experts who agreed on 15 PICO questions based on managing patients with coagulation disorders in dental surgical procedures, such as fitting of implants or dental extractions. Results: The 15 PICO questions were answered based on the available evidence, being limited in most cases due to the lack of a control group. Two of the PICO questions were answered by the experts with a grade C recommendation, while the rest were answered with grade D. Conclusions: The results of this review highlight the need to undertake well designed clinical trials with control groups and with a representative sample size. [ABSTRACT FROM AUTHOR]
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- 2024
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14. Influence of abutment shape on peri‐implant tissue conditions: A randomized clinical trial.
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Bernabeu‐Mira, Juan Carlos, Peñarrocha‐Diago, María, Viña‐Almunia, José, Romero‐Gavilán, Francisco, Pérez‐Sayans, Mario, and Peñarrocha‐Oltra, David
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DENTAL abutments , *IMMEDIATE loading (Dentistry) , *CLINICAL trials , *GINGIVAL hemorrhage , *DENTURES , *PERIODONTAL pockets , *DENTAL implants - Abstract
Objective: To analyze the influence of 3‐mm high abutments with different shapes (cylindrical abutment vs. wide abutment) on marginal bone‐level changes (bone loss and bone remodeling). The influence of abutment shape on implant success, probing pocket depth (PPD), and bleeding on probing (BoP) was studied as secondary objectives. Materials and Methods: Patients with a partially edentulous area requiring fixed dental prostheses by two implants in the posterior mandible or maxilla were included. The implants were 1 mm subcrestally placed, and osseointegration healing was submerged. Three‐mm high abutments with two different shapes were randomly placed in second‐stage surgery: cylindrical abutments (cylindrical group) and wide abutments (wide group). Marginal bone‐level changes were measured using parallelized periapical radiographs at abutment placement, at definitive prosthesis placement, and at 1, 3, 6, and 12 months after loading. PPD and BoP were likewise measured at the control visits. Results: Sixty‐four dental implants in 25 patients were included. Statistically significant differences were found in bone‐level changes. The cylindrical group exhibited less mean marginal bone remodeling (MBR) and marginal bone loss (MBL) than the wide group (p <.05). Moreover, the cylindrical group showed significantly less BoP (p <.05). Conclusion: Abutment shape had a significant influence upon marginal bone‐level changes during the first 12 months. Cylindrical abutments caused less MBR and MBL than wide abutments. More clinical studies involving longer follow‐ups and analyzing other abutment modifications are needed to improve our understanding of how abutments can affect peri‐implant tissue stability. [ABSTRACT FROM AUTHOR]
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- 2023
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15. Influence of Facial Bone Thickness After Implant Placement into the Healed Ridges on the Remodeled Facial Bone and Considering Soft Tissue Recession: A Systematic Review.
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Aizcorbe-Vicente, Javier, Peñarrocha-Oltra, David, Canullo, Luigi, Soto-Peñaloza, David, and Peñarrocha-Diago, María
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BONE remodeling ,BONE resorption ,COMPACT bone ,MEDLINE ,ONLINE information services ,ORAL mucosa ,POSTOPERATIVE period ,COMPLICATIONS of prosthesis ,SYSTEMATIC reviews ,TREATMENT effectiveness ,PERI-implantitis ,DISEASE risk factors - Abstract
Purpose: A systematic review was performed of the dimensional changes in facial cortical bone following implant placement into healed ridges, with the aim of establishing a minimum bone thickness that limits such changes. The influence of such bone remodeling upon the soft tissues and implant survival was also evaluated. Materials and Methods: A search was done of two electronic databases (MEDLINE via PubMed and CENTRAL), complemented by a manual search and lists of references. The risk of bias and methodological quality were assessed using the Cochrane Collaboration tool, the Methodological Index for Non-randomized Studies (MINORS), and the Quality Appraisal Checklist for Case Series. Results: The search yielded 536 publications, of which 11 (four randomized clinical trials, two non-randomized clinical trials, and five case series) were entered in the review. All the included studies reported vertical and horizontal implant facial bone resorption. Decreased facial bone thickness was correlated with increased vertical bone resorption, which in turn was associated with slight soft tissue retraction. A meta-analysis could not be performed, due to the heterogeneity of the study designs and measurement sites. Conclusion: No minimum facial bone thickness was seen that would completely avoid peri-implant bone loss and maintain soft tissue stability. However, a thickness of approximately 2 mm was associated with diminished vertical bone resorption and less peri-implant mucosal recession. [ABSTRACT FROM AUTHOR]
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- 2020
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16. Implants Placed Simultaneously With Particulated Bone Graft in Patients Diagnosed With Recessive Dystrophic Epidermolysis Bullosa
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Peñarrocha-Oltra, David, Aloy-Prósper, Amparo, Ata-Ali, Javier, Peñarrocha-Diago, María, and Peñarrocha-Diago, Miguel
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- 2012
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17. Full-arch fixed prosthesis supported by four implants in patients with recessive dystrophic epidermolysis bullosa
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Peñarrocha-Oltra, David, Peñarrocha-Diago, María, Balaguer-Martínez, Jose, Ata-Ali, Javier, and Peñarrocha-Diago, Miguel
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- 2011
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18. Clinical Characteristics, Treatment, and Evolution in 14 Cases of Pediatric Orofacial Lymphangioma
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Bonet-Coloma, Cristina, Minguez-Martínez, Ignacio, Aloy-Prósper, Amparo, Rubio-Serrano, Minerva, Peñarrocha-Diago, Maria A., and Peñarrocha-Diago, Miguel
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- 2011
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19. Prevalence, Location, and Size of Maxillary Sinus Septa: Panoramic Radiograph Versus Computed Tomography Scan
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Maestre-Ferrín, Laura, Carrillo-García, Celia, Galán-Gil, Sónnica, Peñarrocha-Diago, María, and Peñarrocha-Diago, Miguel
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- 2011
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20. Immediate Versus Nonimmediate Placement of Implants for Full-Arch Fixed Restorations: A Preliminary Study
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Peñarrocha-Diago, Maria A., Maestre-Ferrín, Laura, Demarchi, Carla Leandro, Peñarrocha-Oltra, David, and Peñarrocha-Diago, Miguel
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- 2011
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21. Clinical Characteristics, Treatment, and Evolution of 89 Mucoceles in Children
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Mínguez-Martinez, Ignacio, Bonet-Coloma, Cristina, Ata-Ali-Mahmud, Javier, Carrillo-García, Celia, Peñarrocha-Diago, Maria, and Peñarrocha-Diago, Miguel
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- 2010
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22. Laser Therapy for Infected Sites and Immediate Dental Implants in the Esthetic Zone: A Case Report and Review of Literature
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Crippa, Rolando, Aiuto, Riccardo, Dioguardi, Mario, Peñarrocha-Diago, María, Peñarrocha-Diago, Miguel, and Angiero, Francesca
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Article Subject - Abstract
Placement of postextraction dental implants has become a common practice. Here, we reviewed current literature, along with clinical procedures, outcomes, and incidence of complications, associated with immediate implants in infected postextraction sites. The YSGG (yttrium, scandium, gallium, and garnet) laser can significantly reduce the bacterial concentration after extracting a compromised tooth. We treated a 40-year-old woman with a compromised tooth in the esthetic zone, presenting clinical and radiological signs of infection, particularly a periapical periodontitis. The tooth was extracted after administering local anesthesia using Optocain® (mepivacaine and adrenalin 1 : 100,000), following which the site was treated with an ErCr : YSGG (erbium, chromium-doped yttrium, scandium, gallium, and garnet) 2780 nm laser device (Biolase iPlus®). The implant (Straumann® fixture) was inserted with minimum 35 N torque, 1 mm below the most apical bone peak. Bio-Oss® and resorbable membrane were applied to improve bone healing. The use of ErCr : YSGG laser has ensured success of implant therapy performed on an infected site. There were no complications such as peri-implantitis or loss of peri-implant bone. The implant achieved good primary stability, immediate placement into an infected site did not increase complications, and the 5-year follow-up confirmed the treatment success.
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- 2020
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23. Ultrastructural study by backscattered electron imaging and elemental microanalysis of biomaterial-to-bone interface and mineral degradation of bovine xenografts in maxillary sinus floor elevation
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Ramírez-Fernández, María Piedad, Calvo-Guirado, José Luis, Delgado-Ruiz, Rafael Arcesio, Maté-Sánchez del Val, José Eduardo, Negri, Bruno, and Peñarrocha Diago, María
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- 2013
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24. Is periapical surgery follow-up with only two-dimensional radiographs reliable? A retrospective cohort type sensitivity study.
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Ramis-Alario, Amparo, Tarazona-Álvarez, Beatriz, Peñarrocha-Diago, Miguel, Soto-Peñaloza, David, Peñarrocha-Diago, María, and Peñarrocha-Oltra, David
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RADIOGRAPHS ,PANORAMIC radiography ,CONE beam computed tomography ,RADIOGRAPHY ,AREA measurement - Abstract
Background: Two-dimensional (2D) radiographic techniques are commonly used for assessing lesion prognosis after endodontic surgery. The present retrospective cohort study analyzes the sensitivity and ability of different radiographic techniques in obtaining area and volume measurements of periapical lesions. Material and Methods: Preoperative and follow-up (6-48 months) periapical and panoramic radiographs (index test) and cone-beam computed tomography (CBCT) images (reference standard) were selected from an endodontic microsurgery database. Sensitivity was analyzed independently by two examiners. The areas of the 2D radiographic images and CBCT volumes were studied using Itk-Snap software and Romexis viewer. Results: The sample comprised 105 patients and 105 teeth, with a mean follow-up of 21 months (range 6-48). Preoperatively, CBCT detected all the periapical areas, periapical radiography detected 67, and panoramic radiography detected 60. Postoperatively, of the 52 cases in which CBCT detected remains of the periapical area, periapical radiography detected 22, and panoramic radiography detected 17. The measurements of the areas obtained by the 2D methods, and the volumes obtained by CBCT, had to be transformed into linear measures for comparison purposes. The measurements were found to be significantly different in both the preoperative and the follow-up images. Conclusions: Periapical radiography showed greater sensitivity than panoramic radiography, both preoperatively and at follow-up. The lesions measured with CBCT were larger, with significant differences than as evidenced by the periapical and panoramic radiographs. [ABSTRACT FROM AUTHOR]
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- 2021
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25. Palatal Positioning of Implants in Severely Atrophic Edentulous Maxillae: Five-Year Cross-Sectional Retrospective Follow-up Study.
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Peñarrocha-Oltra, David, Candel-Martí, Eugenia, Peñarrocha-Diago, Miguel, Martínez-González, Jose María, Aragoneses, Juan Manuel, and Peñarrocha-Diago, María
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PALATE surgery ,BONE resorption ,DENTAL plaque ,DENTAL implants ,JAW diseases ,LONGITUDINAL method ,HEALTH outcome assessment ,PATIENT satisfaction ,QUALITY of life ,QUESTIONNAIRES ,PANORAMIC radiography ,SCALE analysis (Psychology) ,SURGICAL complications ,TREATMENT effectiveness ,CROSS-sectional method ,RETROSPECTIVE studies ,DESCRIPTIVE statistics - Abstract
Purpose: To evaluate the 5-year outcome of a previously reported case series of patients with severely atrophic maxillae treated with palatally positioned implants and fixed full-arch rehabilitations. Materials and Methods: A retrospective cross-sectional clinical study of patients treated between January 2000 and January 2004 with palatally positioned implants was carried out. The parameters evaluated at the 5-year follow-up visit were: implant success rate, peri-implant soft-tissue conditions, biological and prosthetic post-loading complications, radiographic peri-implant marginal bone loss, and patient satisfaction. Results: A total of 33 patients with 151 palatally positioned implants were included in the study; 15 patients had received cemented prostheses and 18 had received screwed full-arch prostheses. The success rate for palatally positioned implants after 5 years was 98.7%. Average peri-implant mucosa retraction was 0.39 ± 0.94 mm and the average probing depth was 2.89 ± 0.77 mm. Plaque Index was 0 in 63.1% of the implants, 1 in 18.8%, 2 in 8.7%, and 3 in 9.4%. The modified Bleeding Index was 0 in 71.1%, 1 in 14.1%, and 2 in 14.8%. Mucositis was found in 5.2% of the implants and none had peri-implantitis. Prosthetic complications occurred in 12.1% of the cases. Average peri-implant marginal bone loss was 1.03 ± 1.28 mm. General patient satisfaction averaged 8.2 ± 1.8 according to a 10-point visual analog scale, and good quality of life was reported by most patients. Conclusions: Palatally positioned implants were found to be an adequate treatment for patients with severely atrophic maxillae. A high implant success rate, good peri-implant soft tissue stability, low marginal bone loss, high patient satisfaction and few complications were registered. [ABSTRACT FROM AUTHOR]
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- 2013
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26. Clinical, Microbiologic, and Host Response Characteristics in Patients with Peri-implant Mucositis.
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Ata-Ali, Javier, Flichy-Fernández, Antonio Juan, Ata-Ali, Fadi, Peñarrocha-Diago, María, and Peñarrocha-Diago, Miguel
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BIOLOGICAL assay ,BONE resorption ,CHI-squared test ,CONFIDENCE intervals ,DENTAL implants ,INTERLEUKINS ,MUCOUS membrane diseases ,T-test (Statistics) ,U-statistics ,DATA analysis software ,DESCRIPTIVE statistics ,DIAGNOSIS - Abstract
Purpose: To analyze the clinical, microbiologic, and host response characteristics (interleukins 1β and 6) in the peri-implant sulcus fluid (PISF) of patients with healthy dental implants and with peri-implant mucositis.Materials and Methods: Clinical parameters (modified Gingival Index [mGI], modified Plaque Index [mPI],probing pocket depth [PPD], and absence or presence of radiologic bone loss) were recorded, and PISF samples were obtained from peri-implant sites showing mucositis as well as healthy sites. The periodontopathogenic bacteria Tannerella forsythia (Tf), Treponema denticola (Td), and Porphyromonas gingivalis (Pg) were evaluated, together with the total bacterial load (TBL) and the interleukin (IL) 1βand IL-6 values. Results: The study population consisted of 34 individuals, and 77 dental implants were evaluated during the study (23 mucositis and 54 healthy peri-implant sites). The mGI, mPI, and PPD scores of the peri-implant mucositis group were significantly greater than in the healthy group. No differences in detection frequency were found for putative periodontal pathogens and TBL between the healthy peri-implant sites and mucositis sites. The mucositis group showed a significantly greater expression of IL-6 than the healthy group (P < .05). Although IL-1β was increased in the mucositis group, there was no statistically significant difference versus the healthy implant group. Conclusions: An analysis was made of the clinical, microbiologic, and host response characteristics in implants with peri-implant mucositis, establishing comparisons with healthy implants. In the patients studied, bacterial plaque induced an inflammatory response that can lead to the development of peri-implant mucositis. Adequate plaque control is therefore able to increase peri-implant health, avoiding the risk of future complications. No specific association to the studied bacterial species was established. [ABSTRACT FROM AUTHOR]
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- 2013
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27. Pain and quality of life after endodontic surgery with or without advanced platelet-rich fibrin membrane application: a randomized clinical trial.
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Soto-Peñaloza, David, Peñarrocha-Diago, Miguel, Cervera-Ballester, Juan, Peñarrocha-Diago, María, Tarazona-Alvarez, Beatriz, and Peñarrocha-Oltra, David
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PLATELET-rich fibrin ,CLINICAL trials ,PAIN perception ,QUALITY of life ,POSTOPERATIVE pain ,MEMBRANE filters - Abstract
Background: Clinical evidence of the autologous platelet concentrates effects on the patient-reported outcome measures (PROMs) after endodontic surgery is still limited. Objectives: To investigate the effect of the advanced platelet-rich fibrin (A-PRF+) membrane application upon patient postoperative pain, and quality of life in endodontic surgery. Materials and methods: A two-parallel-arm randomized clinical trial was made comparing endodontic surgery with or without A-PRF+ as adjunctive treatment. Fifty individuals comprehending 50 apical lesions (second premolar to the second premolar) of upper maxilla were included. Pain perception and quality of life (functional limitations and other symptoms) were assessed 1 week after surgery using a visual analog scale and a Likert scale-based questionnaire. Descriptive analysis was done using χ
2 and t test. Binary logistic regression, ANOVA-type statistic, and GEE analysis were used for inferential analysis. Results: Pain perception was mild in both groups [A-PRF+ 12.7 ± 8.5] versus [no A-PRF+ 20.7 ± 16.3]; it proved less variable during the first 4 days in test group, showing lower extreme pain values (p = 0.096). Analgesic use was similar in both groups. Controls reported significantly worse sleep and speech functions (p < 0.05). Bleeding and bad taste/breath were the most discriminative symptoms. Conclusions: Postoperative pain perception was mild in endodontic surgery of the upper anterior maxilla. Differences in pain perception were not statistically significant. The use of A-PRF+ afforded less variable pain perception than in the controls. Altered quality of life parameters were more prevalent in the control group and prove significant for speech and sleep functions. Clinical relevance: Patient-related outcomes are of utmost importance in clinical practice. The use of A-PRF+ provides an affordable and safe alternative to improve postoperative quality of life in endodontic surgery. [ABSTRACT FROM AUTHOR]- Published
- 2020
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28. Implant survival after surgical treatment of early apical peri-implantitis: An ambispective cohort study covering a 20-year period.
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Peñarrocha-Diago, María A., Blaya-Tárraga, Juan Antonio, Menéndez-Nieto, Isabel, Peñarrocha-Diago, Miguel, and Peñarrocha-Oltra, David
- Subjects
PERI-implantitis ,GUIDED bone regeneration ,TREATMENT effectiveness ,COHORT analysis ,GUIDED tissue regeneration ,TOOTH transplantation ,STANDARD deviations - Abstract
Purpose: To describe implant survival at least 1 year after the surgical treatment of early apical peri-implantitis (EAP) and explore potential risk factors of failure of such treatment. Materials and methods: An ambispective cohort study was conducted, involving all patients in whom EAP was detected and surgically treated between 1996 and 2016. Reporting followed the STROBE guidelines. The time from implant placement (IP) to EAP surgery (EAPS), the diagnostic stage and intraoperative variables (location, apical lesion in the tooth being replaced, mesial and distal tooth-implant distance measured at the apex, periapical surgery of the adjacent tooth, guided bone regeneration, implant resection, explantation) were recorded to determine their impact upon treatment outcome. Results: The initial sample consisted of 58 implants in 46 patients. The mean time from IP to EAPS was 21.7 ± 10.1 days. At the time of surgery, eight implants presented mobility and were explanted. The final sample consisted of 50 implants in 39 patients evaluated for implant survival after surgical treatment. A cumulative survival rate of 78.3% was recorded. The mean survival time of the EAP treated implants was 85.4 months (standard deviation [SD] 5.94). The diagnostic stage (P < 0.001) and the existence of a previous periapical lesion in the tooth being replaced (P = 0.022) had a significant influence upon implant survival. Conclusions: The cumulative survival rate was 78.3%, with a mean survival time of 85.4 months. The diagnostic stage of EAP and the presence of a lesion in the tooth being replaced significantly influenced the survival of implants with EAP subjected to surgical treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2020
29. Factors associated with early apical peri-implantitis: A retrospective study covering a 20-year period.
- Author
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Peñarrocha-Oltra, David, Blaya-Tárraga, Juan Antonio, Menéndez-Nieto, Isabel, Peñarrocha-Diago, Miguel, and Peñarrocha-Diago, María
- Subjects
PERI-implantitis ,PERIAPICAL diseases ,DENTAL implants ,SURGICAL complications ,RETROSPECTIVE studies ,TEETH - Abstract
Purpose: To explore risk indicators potentially associated with early apical peri-implantitis (EAP). Materials and methods: A retrospective survey was performed in 2017 with recorded information from patients receiving dental implants between 1996 and 2016. Reporting follows the STROBE (strengthening the reporting of observational studies in epidemiology) guidelines. Data were collected from the medical histories and radiographs: diagnosis of EAP (health/disease), gender, age, type of surgery (immediate/delayed placement), implants placed (position, width, length, location, mesial and distal tooth-implant distance measured at the apex, state of the adjacent tooth and tooth being replaced, and surgical complications. Once the EAP had developed, data were collected regarding days of evolution, symptoms, signs and radiological findings. Results: A total of 2548 patients (57.1% females and 42.9% males) with 8110 implants were enrolled in the study. 46 patients with 58 implants were diagnosed with EAP -- 23 in the maxilla (39.6%) and 35 in the mandible (60.4%) -- between 6 and 50 days after implant placement, with a mean period of 21.7 days (SD 10.1). The frequency of EAP was 1.81% in patients and 0.71% in implants. Immediate placement multiplied the odds of developing EAP 21-fold (95% CI 6.74 to 65.7; P < 0.001) versus delayed placement. The existence of an apical lesion in the tooth being replaced multiplied the odds of developing EAP 26.3-fold (95% CI 4.24 to 162.8; P < 0.001). Replacing a tooth endodontically treated increased the odds 3.48 times (95% CI 0.99 to 12.3; P = 0.052). The presence of an adjacent endodontically treated tooth increased the odds 0.97-fold (95% CI 0.26 to 3.60; P = 0.963). An apical mesial distance of ≤ 1.5 mm increased the odds up to 5.12-fold (95%CI 2.12 to 12.4; P < 0.001). Conclusions: The presence of endodontic periapical lesions or endodontic treatment in the tooth being replaced, immediate implant placement or mesial tooth-implant distance measured at the apex were significantly associated with increased odds of EAP. [ABSTRACT FROM AUTHOR]
- Published
- 2020
30. Influence of supracrestal tissue attachment thickness on radiographic bone level around dental implants: A systematic review and meta‐analysis.
- Author
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Díaz‐Sánchez, María, Soto‐Peñaloza, David, Peñarrocha‐Oltra, David, and Peñarrocha‐Diago, María
- Subjects
SYSTEMATIC reviews ,DENTAL implants ,CONNECTIVE tissues ,ALVEOLAR process surgery ,BONE resorption ,PERIODONTITIS ,AGE distribution ,CONFIDENCE intervals ,MEDLINE ,ONLINE information services ,STATISTICAL significance - Abstract
The present systematic review and meta‐analysis was carried out to determine the extent to which supracrestal tissue attachment (STA) thickness affects marginal bone loss (MBL) around dental implants. An electronic search was conducted in PubMed (MEDLINE), EMBASE, and complementary sources covering the period up to June 2018. The studies were meta‐analyzed based on implant position with respect to the alveolar bone crest (crestal/supracrestal). The MBL values were categorized according to STA width (thick/thin). Of the 1062 eligible titles, nine articles were included in the review. The implants were positioned crestal or supracrestal with respect to the alveolar ridge. The difference between (thin/thick) STA was statistically significant among analytical subsets in terms of lesser MBL (crestal‐positioned: weighted mean difference [WMD] = 0.52, 95% CI [0.03‐1.01]; P = 0.036; supracrestal‐positioned: WMD = 1.26; 95% CI [1.12‐1.39]; P = 0.00; pooled analysis: WMD = 0.73; 95% CI [0.033‐1.13]; P < 0.01). Implant positioning and patient age showed statistical significance in the meta‐regression analysis. The heterogeneity explained by age was R2 = 39.8%. Despite its limitations, the present study demonstrates that implants with thin STA result in greater MBL. There is moderate certainty of the evidence for a large effect of MBL prevention "in favor" of a thick STA environment in crestal‐positioned implants and the pooled analysis, but lesser certainty when only supracrestal‐positioned implants are considered. No trials studying this topic in subcrestal‐positioned implants were found. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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- View/download PDF
31. Comparison of Immediate and Delayed Implants in the Maxillary Molar Region: A Retrospective Study of 123 Implants.
- Author
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Peñarrocha-Oltra, David, Demarchi, Carla Leandro, Maestre-Ferrín, Laura, Peñarrocha-Diago, Miguel, and Peñarrocha-Diago, María
- Subjects
AGE distribution ,COMPARATIVE studies ,STATISTICAL correlation ,DENTAL implants ,MAXILLA ,MEDICAL protocols ,MOLARS ,HEALTH outcome assessment ,PROSTHETICS ,SEX distribution ,T-test (Statistics) ,SAMPLE size (Statistics) ,TREATMENT effectiveness ,RETROSPECTIVE studies - Abstract
Purpose: The purpose of this study was to compare marginal bone loss and success rates 1 year after implants had been placed in maxillary molar sites, either immediately postextraction or after the extraction sites had healed (delayed). Materials and Methods: A retrospective case study was made of subjects treated with immediate or delayed dental implants in the maxillary molar region between January 2006 and December 2008. A protocol was prepared in which patient age, sex, implant length and diameter, type of prosthesis, buccal plate width, and use of bone grafting were recorded. After 12 months, data relating to the clinical and radiologic conditions of the implants and the success rate according to the criteria of Buser et al were recorded. The variables were analyzed statistically (Student t test, Pearson correlation, Games- Howell test). Results: The study included 123 implants placed in 70 patients; 35 implants were immediate and 88 were delayed. Two immediate and six delayed implants failed, resulting in success rates of 94.3% and 93.2%, respectively. Average marginal bone loss was 0.56 mm for immediate implants and 0.67 mm for delayed implants. Conclusions: The placement of immediate implants in maxillary molar sites achieved similar results to implants placed in healed sites in the same region after 12 months. No statistically significant differences were found between implant survival rates or average marginal bone loss. [ABSTRACT FROM AUTHOR]
- Published
- 2012
32. Relationships Between Bone Density Values from Cone Beam Computed Tomography, Maximum Insertion Torque, and Resonance Frequency Analysis at Implant Placement: A Pilot Study.
- Author
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Fuster-Torres, Maria Ángeles, Peñarrocha-Diago, María, Peñarrocha-Oltra, David, and Peñarrocha-Diago, Miguel
- Subjects
MANDIBLE surgery ,MAXILLA surgery ,TOMOGRAPHY ,AGE distribution ,ANALYSIS of variance ,STATISTICAL correlation ,DENTAL arch ,DENTAL casting ,DENTURES ,DENTAL implants ,JAW diseases ,MANDIBLE ,MAXILLA ,PROBABILITY theory ,PANORAMIC radiography ,SEX distribution ,STATISTICS ,T-test (Statistics) ,TORQUE ,TRANSDUCERS ,VIBRATION (Mechanics) ,PILOT projects ,DATA analysis ,BONE density ,RETROSPECTIVE studies ,DATA analysis software ,SURGERY - Abstract
Purpose: The aim of the present study was to determine bone density in designated implant sites using cone beam computed tomography (CBCT) and to evaluate possible correlations between age, gender, insertion torque measurements, and resonance frequency analysis (RFA) values. Materials and Methods: Completely and partially edentulous patients were treated with implants between 2007 and 2008 and evaluated retrospectively. The preoperative examination included a panoramic radiograph, CBCT, diagnostic casts, and a clinical examination of the jaws. With the CBCT scans, bone densities were recorded in Hounsfield units (HU). Insertion torque values and implant stability measurements (via RFA) were also noted. Results: Mean bone density and insertion torque values were 623 ± 209 HU and 42.4 ± 4 Ncm, respectively, for the 82 implants placed. Mean primary stability (implant stability quotient) was 62.4 ± 8. The differences in mean bone density at implant sites in the mandible (717 ± 204 HU) and the maxilla (490 ± 128 HU) were statistically significant for all patients (P < .05). There was a statistically significant relationship between bone density values and insertion torque measurements for implant sites in the anterior mandible (r = 0.562, P < .05), as well as between bone density and RFA values for men (r = 0.412, P < .05). Conclusions: Bone density measurements using preoperative CBCT may be helpful as an objective diagnostic tool. These values, in conjunction with RFA values and insertion torque measurements, can provide the implant surgeon with an objective assessment of bone quality and may be especially useful where poor-quality bone is suspected. [ABSTRACT FROM AUTHOR]
- Published
- 2011
33. Radiographic Findings in the Maxillary Sinus: Comparison of Panoramic Radiography with Computed Tomography.
- Author
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Maestre-Ferrín, Laura, Galán-Gil, Sónnica, Carrillo-García, Celia, and Peñarrocha-Diago, María
- Subjects
ORAL disease diagnosis ,PANORAMIC radiography ,TOMOGRAPHY ,CHI-squared test ,MAXILLARY sinus ,STATISTICS ,EQUIPMENT & supplies - Abstract
Purpose: To assess the prevalence of radiographic signs of maxillary sinus pathology in patients undergoing dental implant treatment and to compare the efficacy of panoramic radiography, computed tomography (CT), and three-dimensional (3D) CT with Implametric software in the diagnosis of sinus pathology. Materials and Methods: Thirty patients were selected at random from those being treatment-planned to receive implant-supported restorations in the maxilla and who had a panoramic radiograph, a conventional CT scan in acetate, and a 3D CT scan in digital format. The radiographic maxillary sinus findings were categorized as: (1) no sign of pathology, (2) mucosal thickening, (3) mucous cyst, or (4) occupation of the entire sinus. Results: Seventeen women and 13 men were included, with a mean age of 50.9 years. There was a 38.3% prevalence of radiographic abnormalities (23.3% mucosal thickenings, 10% mucous cysts, and 5% occupation of the entire sinus). Of the 23 sinuses that displayed radiographic signs of pathology, only 1 (4.3%) was correctly diagnosed by the panoramic radiograph. Conclusions: The most common radiographic maxillary sinus finding was mucosal thickening, followed by mucous cysts and occupation of the whole sinus. Conventional CT can be considered a reliable method for the diagnosis of maxillary sinus pathology. [ABSTRACT FROM AUTHOR]
- Published
- 2011
34. Hemostatic agents in endodontic surgery of maxillary molars: A randomized controlled pilot study of polytetrafluoroethylene (PTFE) strips as an adjunct to epinephrine impregnated gauze versus aluminum chloride.
- Author
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Peñarrocha-Oltra, David, Soto-Peñaloza, David, Peñarrocha-Diago, Miguel, Cervera-Ballester, Juan, Cabanes-Gumbau, Guillermo, and Peñarrocha-Diago, María
- Subjects
ALUMINUM chloride ,POLYTEF ,SURGICAL hemostasis ,MOLARS ,LOGISTIC regression analysis ,PILOT projects - Abstract
Background: Hemostasis is of critical importance in endodontic surgery. Studies on bleeding control in maxillary molars are scarce. The present study compares the efficacy of two hemostatic techniques in controlling bleeding in endodontic surgery. Material and Methods: A randomized two-arm pilot study involving 30 patients with peri-radicular lesions in maxillary molars (first and second molars) was carried out including the following hemostatic agents: polytetrafluoroethylene (PTFE) strips as an adjunct to epinephrine impregnated gauze (test group; n = 15) and aluminum chloride (Expasyl™) (control; n = 15). Bleeding control was independently assessed by the surgeon and by two blinded observers before and after application of the hemostatic agent, and was classified as either adequate (complete bleeding control) or inadequate (incomplete bleeding control).Results: Bleeding control was similar in both groups. Simple binary logistic regression analysis failed to identify variables affecting bleeding control. Only the height of the keratinized mucosal band (≥ 2 mm) suggested a decreased risk of inadequate bleeding control of up to 89% (OR=0.11; p=0.06). Conclusions: No difference in the efficacy of bleeding control was observed between PTFE strips as an adjunct to epinephrine impregnated gauze and aluminum chloride in maxillary molars. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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- View/download PDF
35. Oral rehabilitation with dental implants in patients with recessive dystrophic epidermolysis bullosa: A retrospective study with 2-15 years of follow-up.
- Author
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Peñarrocha-Oltra, David, Agustín-Panadero, Rubén, Serra-Pastor, Blanca, Peñarrocha-Diago, María, and Peñarrocha-Diago, Miguel
- Subjects
OVERLAY dentures ,DENTAL implants ,EPIDERMOLYSIS bullosa ,MAXILLA ,CONE beam computed tomography - Published
- 2020
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36. Floor of the mouth hemorrhage subsequent to dental implant placement in the anterior mandible.
- Author
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Peñarrocha-Diago, María, Balaguer-Martí, José Carlos, Peñarrocha-Oltra, David, Bagán, José, Peñarrocha-Diago, Miguel, and Flanagan, Dennis
- Abstract
Complications in dental implant surgery are possible. Bleeding complications have been described that may be serious, particularly in the floor of the mouth. We present two cases of sublingual hematomas during dental implant osteotomies that impeded but did not close the airway. The clinical courses of these patient's complications are reviewed. One patient had immediate hematoma formation while the other developed a hematoma overnight, presenting the next day. The treatment rendered was a precautionary in-hospital tracheotomy for the first patient and only compression control for the second. Bleeding complications during dental implant placement in the anterior mandible can be serious issues. There is a potential for sublingual hematoma that could compromise the airway by pressing the tongue against the soft palate into the pharynx. In-hospital treatment may be necessary to prevent an adverse outcome. It must be noted that a hematoma in the submandibular space is life threatening by direct airway compression. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
37. Impact of crestal and subcrestal implant placement upon changes in marginal peri-implant bone level. A systematic review.
- Author
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Pellicer-Chover, Hilario, Díaz-Sanchez, María, Soto-Peñaloza, David, Peñarrocha-Diago, María, Canullo, Luigi, and Peñarrocha-Oltra, David
- Subjects
STANDARDIZATION ,MEDLINE ,BONES ,META-analysis ,MANNOSE-binding lectins ,ELECTRONIC information resource searching ,CLINICAL trials - Abstract
Background: To systematically assess studies analyzing peri-implant bone loss in implants placed in crestal and subcrestal position. Material and Methods: Following the recommended methods for systematic reviews and meta-analyses (PRISMA), an electronic search was conducted in the PubMed (MEDLINE), EMBASE and LILACS databases to identify all relevant articles published up until April 2017. The search included human studies comparing marginal bone loss (MBL) between a control group and a study group with a minimum of 10 patients and a minimum follow-up of 6 months after prosthetic loading with rough neck implants. Two independent reviewers assessed the risk of bias in the selected studies based on the Newcastle-Ottawa scale for observational studies and the Cochrane Collaboration for clinical trials. Results: Of 342 potentially eligible items, 7 complied with the inclusion criteria. One article was retrieved through the manual search. Eight articles were finally included: five experimental and three observational studies. The risk of bias assessed by the Cochrane Collaboration and Newcastle-Ottawa showed a high risk of bias. The mean followup period was 21 months (range 6-36 months). In four studies, implants placed in a crestal position presented higher MBL than subcrestal implants - the differences being significant in one study, while in three studies, implants placed in a subcrestal position presented greater MBL than crestal implants, with significant differences in only one study. Conclusion: Despite its limitations, the present systematic review did not find better outcomes between crestal and subcrestal implant placement, however, new studies will be needed, involving improved designs and the standardization of protocols to allow statistical comparisons and the drawing of firm conclusions. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
38. Volumetric variation of peri-implant soft tissues in convergent collar implants and crowns using the biologically oriented preparation technique (BOPT).
- Author
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Cabanes-Gumbau, Guillermo, Pascual-Moscardó, Agustín, Peñarrocha-Oltra, David, García-Mira, Berta, Aizcorbe-Vicente, Javier, and Peñarrocha-Diago, María
- Subjects
DENTAL implants ,COLORIMETRY ,TISSUES ,CROWNS ,OVERLAY dentures ,MANDIBULAR prosthesis ,PERIODONTAL probe ,SCALING (Social sciences) - Abstract
Background: To evaluate the changes in the peri-implant soft tissues of convergent collar implants with biologically oriented preparation technique (BOPT) crowns, 10 months after loading. Material and Methods: A pilot study was carried out from January 2016 to October 2017 involving 14 patients with one or two implants in the posterior mandibular sector. A total of 32 convergent collar implants were placed using a non-submerged protocol. Three months later the provisional cemented crowns were fitted using the BOPT approach with the finish line 1-1.5 mm below the gingival margin, simulating coronal emergence of a natural tooth. The soft tissue changes were measured with an intraoral scanner at two different timepoints: a) on the day of provisionalization, before prosthetic loading; and b) 10 months later without the provisional prosthesis. The STL files were superimposed and the soft tissue changes were recorded using a color scale with measurement of the volumetric changes in mm³. Results: A mean increase in peri-implant mucosal volume of 64.7 mm3 was observed in 29 implants. The zones with the greatest increase in soft tissue volume were the papillae of implants with adjacent teeth and the peri-implant buccal margin. Three implants showed a mean decrease in soft tissue volume of -25.1 mm3. Conclusions: The fitting and design of crowns using the biologically oriented preparation technique (BOPT) over convergent collar implants affords a significant increase in peri-implant soft tissue volume both at the level of the papillae and in the buccal margin. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
39. Oral Teratomas: A Report of 5 Cases
- Author
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Bonet, Cristina, Peñarrocha-Oltra, David, Minguez, J.M., Vera-Sirera, Beatriz, Peñarrocha-Diago, Miguel, and Peñarrocha-Diago, María
- Published
- 2012
- Full Text
- View/download PDF
40. Simultaneous and delayed direct sinus lift versus conventional implants: Retrospective study with 5-years minimum follow-up.
- Author
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Romero-Millán, Javier, Hernández-Alfaro, Federico, Peñarrocha-Diago, Miguel, Soto-Peñaloza, David, Peñarrocha-Oltra, David, and Peñarrocha-Diago, María
- Subjects
SINUS augmentation ,DENTAL implants ,BONES ,MAXILLARY sinus ,RETROSPECTIVE studies ,MAXILLA - Abstract
Background: To compare the radiological parameters and success of posterior maxillary direct sinus lift with simultaneous or delayed implant placement, or implant placement in native bone, after a minimum follow-up period of 5 years. Material and methods: A retrospective cohort study was carried out in a university clinic, selecting patients subjected to implant treatment in the posterior maxilla between the years 2005 and 2011. The patients were divided into three groups: 1) implants placed in native bone; 2) direct sinus lift with simultaneous implant placement; and 3) direct sinus lift with delayed implant placement. Bone crest level, bone loss, vertical bone gain, and implant success and survival after a minimum follow-up period of 5 years after prosthetic loading were analyzed. Results: A total of 163 patients and 329 implants were included in the study. The mean duration of follow-up was 7.0 ± 1.9 years. Bone loss and implant success and survival were very similar in all three groups, with no significant differences among them. Graft reabsorption was greatest during the first 12 months, though graft stabilization was confirmed after 5 years of follow-up. Conclusions: Bone loss and percentage success and survival proved very similar for the implants placed in native bone and for sinus lift with simultaneous or delayed implant placement. The height of the graft material decreased mainly in the first 12 months, and continued until stabilization after 5 years, with no significant variations thereafter. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
41. Horizontal Denture: A Prosthodontic Alternative for Severe Maxillary Atrophy.
- Author
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Peñarrocha-Oltra, David, Candel-Martí, Eugenia, Peñarrocha-Diago, María, Agustín-Panadero, Rubén, Canullo, Luigi, and Peñarrocha, Miguel
- Subjects
EDENTULOUS mouth ,MAXILLARY sinus diseases ,OVERLAY dentures - Abstract
The article presents two clinical case studies of edentulous patients whose severe upper maxillary atrophy conditions were treated using prosthetic approach with horizontal overdentures. Topics discussed include the results of radiographic evaluations of the patients, surgical procedures, and preparations for the horizontal dentures. Postoperative treatment of patients is also mentioned.
- Published
- 2015
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42. Long-term Survival Rates of Implants Supporting Overdentures.
- Author
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Balaguer, José, Ata-Ali, Javier, Peñarrocha-Oltra, David, García, Berta, and Peñarrocha-Diago, María
- Subjects
OVERLAY dentures ,SURVIVAL analysis (Biometry) ,DENTAL implants ,MANDIBLE ,MAXILLA ,EDENTULOUS mouth ,CIGARETTE smokers ,THERAPEUTICS - Abstract
The study aims were to evaluate survival rates of dental implants in patients wearing maxillary and mandibular overdentures in relation to age, sex, smoking, implant splinting or non-splinting, the maxilla rehabilitated, and number of implants per dental arch. This was a prospective study of patients who were completely edentulous in either mandible or maxilla or both, rehabilitated with implant-retained overdentures, with a follow-up of at least 3 years. 95 patients with 107 overdentures were supported by 360 implants were included in the study. Rehabilitations were monitored over an average of 95 ± 20.3 months (range 36-159). Implant survival in the maxilla was 91.9% and in the mandible 98.6%, representing a statistically significant difference (P < .05). Age, sex and implant splinting did not influence survival rates significantly. Smokers presented a lower survival rate. Implant numbers in the maxilla had a significant influence on survival, 100% for 6 but 85.7% for 4. Three mandibular implants achieved higher survival rates (100%) but with 2 (96.6%) or 4 (99%) survival was lower, although without significant difference. Long-term results suggest that 3-implant mandibular overdentures have an equivalent survival rate to 4-implant overdentures. In the maxilla, results showed that 6 implants may be the best treatment strategy. For smokers with fewer implants retaining the overdentures, there were higher numbers of implant failures. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
43. Influence of the prosthetic arm length (palatal position) of zygomatic implants upon patient satisfaction.
- Author
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Pellicer-Chover, Hilario, Cervera-Ballester, Juan, Peñarrocha-Oltra, David, Bagán, Leticia, Peñarrocha-Diago, María, and Peñarrocha-Diago, Miguel
- Subjects
ZYGOMATIC fractures ,DENTAL implants ,PATIENT satisfaction ,PERIODONTICS ,MEDICAL rehabilitation ,THERAPEUTICS - Abstract
Background: To assess the influence of the prosthetic arm length (palatal position) of zygomatic implants upon patient comfort and stability, speech, functionality and overall satisfaction. Material and Methods: A retrospective clinical study was made of patients subjected to rehabilitation of atrophic maxilla with complete maxillary implant-supported fixed prostheses involving a minimum of two zygomatic implants (one on each side) in conjunction with premaxillary implants, and with 12 months of follow-up after implant loading. Subjects used a VAS to score general satisfaction, comfort and stability, speech and functionality, and the results were analyzed in relation to the prosthetic arm length of the zygomatic implants 12 months after prosthetic delivery. Results: Twenty-two patients participated in the study, receiving 22 prostheses anchored on 148 implants (44 were zygomatic and 94 were conventional implants). The mean right and left prosthetic arm length was 5.9±2.4 mm and 6.1±2.7 mm, respectively, with no statistically significant differences between them (p=0.576). The mean scores referred to comfort/retention, speech, functionality and overall satisfaction were high - no correlation being found between prosthetic arm length and patient satisfaction (p=0.815). Conclusions: No relationship could be identified between prosthetic arm length (palatal position) and patient satisfaction. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
44. Impact of crestal and subcrestal implant placement in peri-implant bone: A prospective comparative study.
- Author
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Pellicer-Chover, Hilario, Peñarrocha-Diago, María, Peñarrocha-Oltra, David, Gomar-Vercher, Sonia, Agustín-Panadero, Rubén, and Peñarrocha-Diago, Miguel
- Subjects
DENTAL implants ,IMMEDIATE loading (Dentistry) ,BONE resorption ,TOOTH loss ,DENTAL extraction ,TREATMENT effectiveness ,COMPARATIVE studies ,THERAPEUTICS - Abstract
Background: To assess the influence of the crestal or subcrestal placement of implants upon peri-implant bone loss over 12 months of follow-up. Material and Methods: Twenty-six patients with a single hopeless tooth were recruited in the Oral Surgery Unit (Valencia University, Valencia, Spain). The patients were randomized into two treatment groups: group A (implants placed at crestal level) or group B (implants placed at subcrestal level). Control visits were conducted by a trained clinician at the time of implant placement and 12 months after loading. A previously established standard protocol was used to compile general data on all patients (sex and age, implant length and diameter, and brushing frequency). Implant success rate, peri-implant bone loss and the treatment of the exposed implant surface were studied. The level of statistical significance was defined as 5% (α=0.05). Results: Twenty-three patients (8 males and 15 females, mean age 49.8±11.6 years, range 28-75 years) were included in the final data analyses, while three were excluded. All the included subjects were non-smokers with a brushing frequency of up to twice a day in 85.7% of the cases. The 23 implants comprised 10 crestal implants and 13 subcrestal implants. After implant placement, the mean bone position with respect to the implant platform in group A was 0.0 mm versus 2.16±0.88 mm in group B. After 12 months of follow-up, the mean bone positions were -0.06±1.11 mm and 0.95±1.50 mm, respectively - this representing a bone loss of 0.06±1.11 mm in the case of the crestal implants and of 1.22±1.06 mm in the case of the subcrestal implants (p=0.014). Four crestal implants and 5 subcrestal implants presented peri-implant bone levels below the platform, leaving a mean exposed treated surface of 1.13 mm and 0.57 mm, respectively. The implant osseointegration success rate at 12 months was 100% in both groups. Conclusions: Within the limitations of this study, bone loss was found to be greater in the case of the subcrestal implants, though from the clinical perspective these implants presented bone levels above the implant platform after 12 months of follow-up. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
45. Rehabilitation of the Atrophic Maxilla With Tilted Implants: Review of the Literature.
- Author
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Peñarrocha-Oltra, David, Candel-Martí, Eugenia, Ata-Ali, Javier, and Peñarrocha-Diago, María
- Subjects
MAXILLARY diseases ,ATROPHY ,OVERLAY dentures ,DENTAL implants ,DENTAL radiography ,PATIENT satisfaction - Abstract
We review the evidence-based literature on the use of tilted implants in the rehabilitation of patients with maxillary atrophy. Studies from 1999 to 2010 on patients with atrophic maxilla rehabilitated with tilted implants were reviewed. Clinical series with at least 10 patients rehabilitated using tilted implants and a follow-up of at least 12 months after prosthetic load were included. Case reports and studies with missing data were excluded. In each study the following was assessed: surgical technique, prosthesis type, timing of implant loading, success rate and marginal bone loss of tilted and axial implants, complications and patient satisfaction level. Thirteen studies were included, reporting a total of 782 tilted and 666 axial implants in 319 patients. Success rates went from 91.3% to 100% for axial implants and from 92.1% to 100% for tilted implants; radiographic marginal bone loss went from 0.4 mm to 0.92 mm in tilted implants and from 0.35 mm to 1.21 mm in axial implants. No statistically significant differences were found in any of the studies. No surgical complications and only minor prosthetic complications were reported. High patient satisfaction was found with all types of prosthesis (full-arch fixed, partial fixed and overdentures) placed over tilted implants. The literature on tilted implants shows that implants placed with this technique, both used alone and combined with axially placed implants, and rehabilitated with different prosthetic options have high success rates, minimal complications and high patient satisfaction. However, lack of homogeneity among studies and relatively short follow-up periods for most studies make necessary more studies. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
46. Tilted Implants for the Restoration of Posterior Mandibles With Horizontal Atrophy: An Alternative Treatment.
- Author
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Peñarrocha Diago, María, Maestre Ferrín, Laura, Peñarrocha Oltra, David, Canullo, Luigi, Calvo Guirado, Jose Luis, and Peñarrocha Diago, Miguel
- Abstract
Purpose: Horizontal atrophy in the posterior mandible presents serious limitations on conventional implant placement. The purpose of this study was to evaluate the use of tilted implants angled in a buccolingual direction for restoring atrophic posterior mandibular sectors. Materials and Methods: A cohort study was performed of 25 patients who had partial prostheses supported by more than 1 implant (≥1 tilted and 1 axial implant) to restore molar areas in the mandible. When the bone thickness was at least 5 mm, axial implants were placed; when the alveolar ridge was narrower, the implant was placed with tilted angulation. The beds for these tilted implants were prepared using a lingual approach, tipping the implant apex toward the vestibule. Twelve months after loading, bone loss was evaluated and the success rates of the tilted and axial implants were calculated. Results: The study included 20 women and 5 men (mean age, 54.8 yr) who received 67 implants in the posterior mandibular sectors. Thirty-nine implants were placed with a buccal angulation and 28 implants were placed vertically. Mean bone losses of 0.59 ± 0.26 mm among the tilted implants and 0.48 ± 0.34 mm among the axial implants were observed 1 year after loading. The success rate of the tilted implants was 94.9%, and that of the axial implants was 100%. No significant differences in success rates or in bone loss between the tilted and axial implants were found at 12 months after loading. Conclusions: Twelve months after loading, tilted implants provided good results for the restoration of posterior mandibles with horizontal atrophy and no significant differences in success rates or marginal bone loss between tilted and axial implants were observed. [Copyright &y& Elsevier]
- Published
- 2013
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47. Oral Rehabilitation With Bone Graft and Simultaneous Dental Implants in a Patient With Epidermolysis Bullosa: A Clinical Case Report.
- Author
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Larrazabal-Morón, Carolina, Boronat-López, Araceli, Peñarrocha-Diago, María, and Peñarrocha-Diago, Miguel
- Abstract
Epidermolysis bullosa (EB) represents a group of mainly hereditary skin disorders, manifested by an exceptional tendency of the skin and mucosa to form bullae and vesicles after minor friction and trauma. Oral features include repeated blistering, scar formation, elimination of buccal and vestibular sulci, and alveolar bone resorption. The use of endosseous implants in the fixed prosthetic rehabilitation of patients with recessive dystrophic EB might provide a considerably better outcome than conventional removable prosthetic methods. This clinical report describes the fixed rehabilitation with 2 implants placed simultaneously with bone graft in a partially edentulous patient diagnosed with recessive dystrophic EB. The implants, with simultaneous bone graft, were placed to decrease the number of surgical operations required, avoiding soft tissue ulcerations and discomfort in the patient. This treatment option appears to be favorable for recessive dystrophic EB patients compared with other options involving removable prostheses, which irritate the oral mucosa. [Copyright &y& Elsevier]
- Published
- 2009
- Full Text
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48. Analogical and Digital Workflow in the Design and Preparation of the Emergence Profile of Biologically Oriented Preparation Technique (BOPT) Crowns over Implants in the Working Model.
- Author
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Cabanes-Gumbau, Guillermo, Soto-Peñaloza, David, Peñarrocha-Diago, Miguel, and Peñarrocha-Diago, María
- Subjects
WORKFLOW ,DENTAL technology - Abstract
The Biologically Oriented Preparation Technique (BOPT), developed by Ignacio Loi and published in 2008, is a consolidated concept in the modeling and preservation of pericoronal soft tissues. The present study describes the analogical and digital methods allowing adequate design and preparation of the emergence profile of BOPT crowns in the working model, with a view to comparing the workflow and advantages of each method. At present, not all the digital procedures have been fully optimized to completely replace the traditional analogical methods. Nevertheless, it is only a matter of time until dental digitalization technology totally replaces the analogical clinical methods. The digital workflow for this procedure is quickly implemented and optimized, and represents the most realistic option, with possibilities for further development in the immediate future. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
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49. Immediate dental implant placement in post-extraction-infected sites decontaminated with Er,Cr:YSGG laser: a retrospective cohort study
- Author
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Aiuto, Riccardo, Peñarrocha Diago, Miguel, Peñarrocha Diago, María, Angiero, Francesca, and Departament d'Estomatologia
- Subjects
tooth extraction ,dental implant ,socket preservation ,UNESCO::CIENCIAS MÉDICAS ,Er,Cr:YSGG laser treatment ,CIENCIAS MÉDICAS [UNESCO] ,YSGG laser treatment [Er,Cr] ,oral surgery - Abstract
Antecedentes científicos y objetivos de estudio La técnica quirúrgica para la colocación inmediata de un implante dental en un alvéolo post-extracción fue propuesta inicialmente en 1976 por Schulte y Heimke. La colocación de implantes dentales en alveolos post-extracción ofrece ventajas tales como un tiempo de tratamiento reducido y una mayor comodidad para el paciente; además esta técnica permite reducir la exposición quirúrgica del paciente y limitar la reabsorción fisiológica ósea posterior a la extracción del diente, conservando la estética. La justificación para la extracción de un diente comprometido a menudo está relacionada con la presencia de una lesión periapical, consecuencia de una infección activa. Esto se considera tradicionalmente una de las principales contraindicaciones para la inserción inmediata del implante, debido a la mayor posibilidad de que la infección se propague a los tejidos periimplantarios durante la colocación del implante o en el período de cicatrización. De todos modos, los estudios en animales han demostrado que la presencia de infecciones periodontales o endodónticas activas no compromete la osteointegración de los implantes colocados inmediatos a la exodoncia; además, el contacto hueso-implante (BIC) no se ve comprometido. Tras los primeros estudios, in vitro o en animales, algunos autores han propuesto un protocolo de implantología post-extracción en sitios con infección también en humanos. En una revisión sistemática de la literatura, Corbella et al. encontró nuevos estudios en humanos que incluían tasas de supervivencia que oscilaban entre el 92% y el 100% para un total de 497 implantes colocados en sitios con infecciones endodónticas; el seguimiento varió de 3 a 117 meses después de la carga. Se han propuesto diferentes enfoques para la descontaminación del sitio post-extractivo antes de la inserción del implante. Las medidas para disminuir la carga bacteriana de los sitios con infección incluyen procedimientos mecánicos y químicos como limpieza meticulosa, desbridamiento alveolar, la administración de antibióticos y enjuagues bucales posoperatorios con clorhexidina al 0,12%. Se ha propuesto el uso de láseres como complemento de los procedimientos de desinfección, debido a que la tecnología láser es capaz de eliminar las bacterias de manera más eficaz que los productos químicos. El momento ideal para la colocación del implante después de la extracción dental se ha discutido ampliamente en la literatura, se han atribuido ventajas y desventajas a los diferentes protocolos, aunque existe un interés creciente por acortar el tiempo total de tratamiento y minimizar el número de intervenciones quirúrgicas. Hämmerle et al. en el 2004 propusieron una clasificación para los tiempos de colocación de implantes, según la cual se identifica el implante tipo 1 como el que se coloca inmediatamente tras la extracción del diente, es decir en el mismo acto quirúrgico; el tipo 2 se coloca 4-8 semanas después de la exodoncia, y este tiempo suele corresponder a la maduración de los tejidos blandos; el tipo 3 se pone 12-16 semanas tras la extracción, cuando radiográficamente se puede ver el progreso de maduración del hueso en el sitio post-extracción; el implante tipo 4 se sitúa en un sitio post-extracción ya maduro, es decir por lo menos 16 semanas después de la exodoncia. El implante de tipo 1 reduce el tiempo de tratamiento, utiliza todo el hueso existente disponible en la cresta alveolar y puede evitar la necesidad de levantar un colgajo. Por otro lado, el riesgo de infección (alvéolos infectados) es mayor. En ocasiones, una posible discrepancia entre la superficie del implante y la pared alveolar determina la necesidad de utilizar técnicas de aumento óseo. En situaciones donde sea necesario el avance de un colgajo para cubrir el implante y el posible material de injerto óseo, para conseguir una curación por segunda intención, supone un mayor riesgo de resultados estéticos. En realidad, todos estos inconvenientes también se pueden encontrar con otros protocolos de implantes no inmediatos. El hecho de colocar un implante en un sitio infectado sugiere un mayor riesgo de infección; sin embargo, en los últimos años, la evidencia científica ha dado varias pruebas, de cómo este riesgo es comparable al de los implantes tipo 2, 3 o 4. Existen evidencias de cómo los procedimientos de desbridamiento mecánico y químico del sitio de post-extracción permiten reducir la presencia de bacterias. La imposibilidad de verificar la eliminación completa del biofilm bacteriano del sitio post-extracción junto con la eficacia probada del láser en tejidos duros y blandos ha llevado a algunos autores a proponer el uso del láser para la descontaminación de los alvéolos antes de la colocación del implante. Sin embargo, este método aún no se ha estudiado con ensayos clínicos controlados. El objetivo de este estudio clínico controlado en una muestra de pacientes, realizado con al menos un año de seguimiento después del tratamiento, fue comparar el uso de implantes inmediatos en lugares infectados (tipo 1) descontaminados con láser Er,Cr:YSGG (test) versus implantes convencionales en sitios edéntulos cicatrizados (tipo 4). Los objetivos específicos de la presente tesis fueron: I. Comparar la diferencia en el nivel de hueso marginal (MBL) entre el momento de colocación de los implantes y en final del seguimiento. II. Estudiar el posible fracaso de los implantes las complicaciones (como mucositis y periimplantitis), en el grupo estudio y en el control. Material y métodos Comité de ética Este estudio recibió la aprobación del comité de ética de la Universidad de Valencia (n. 1606937298573) y se realizó en estricto cumplimiento de las declaraciones de STROBE (von Elm et al. 2008). Diseño del estudio Se realizó un estudio de cohortes retrospectivo. Se estudiaron una serie de pacientes tratados entre 2014 y 2019, con un seguimiento mínimo de 1 año, y hasta más de 4 años (no se realizó el cálculo del tamaño muestral, ya que, al ser un estudio retrospectivo, se incluyeron todos los pacientes posibles en el período de tiempo indicado). El estudio se llevó a cabo en el Istituto Stomatologico Italiano de Milán (Italia) y en la Unidad de Cirugía Oral de la Universidad de Valencia (España). Los pacientes tratados fueron informados y firmaron un consentimiento informado donde se explicaba que sus datos podrían usarse con un fin docente o ser usados para investigación. Población del estudio Grupo test (implantes tipo 1 en sitios infectados tratados con láser). Criterios de inclusión: - Pacientes ≥ 18 años. - Sin condiciones médicas relevantes. - Valores del índice de placa y de sangrado al sondaje ≤ 25 % para toda la boca. - Seguimiento mínimo de 1 año después de la cirugía de implantes. - Pacientes que recibieron terapia con implante inmediato en sitios infectados (por presencia de caries subgingival, enfermedad periodontal, lesión endodóncica o fractura) descontaminado con láser. Criterios de exclusión: - Pacientes con enfermedades sistémicas importantes. - Antecedentes de radioterapia. - Tratamiento actual con esteroides. - Discapacidad neurológica o psiquiátrica. - Estado inmunodeprimido. - Pacientes con historia de tratamiento con bisfosfonatos. - Mujeres embarazadas o en periodo de lactancia. - Bruxismo severo. - Pacientes con mala higiene oral y no colaboradores. - Hábito de fumar (más de 15 cigarrillos al día), abuso de drogas o alcohol. Grupo control (implantes tipo 4 en sitios no infectados). Criterios de inclusión: - Pacientes ≥ 18 años. - Sin condiciones médicas relevantes. - Valores del índice de placa y de sangrado al sondaje ≤ 25 % para toda la boca. - Seguimiento mínimo de 1 año después de la cirugía de implantes. - Pacientes que recibieron terapia con implante tipo 4 por edentulismo. Criterios de exclusión: - Pacientes con enfermedades sistémicas importantes. - Antecedentes de radioterapia. - Tratamiento actual con esteroides. - Discapacidad neurológica o psiquiátrica. - Estado inmunodeprimido. - Pacientes con historia de tratamiento con bisfosfonatos. - Mujeres embarazadas o en periodo de lactancia. - Bruxismo severo. - Pacientes con mala higiene oral y no colaboradores. - Hábito de fumar (más de 15 cigarrillos por día), abuso de drogas o alcohol. La primera fase del estudio incluyó la selección de las historias clínicas de los pacientes incluidos en el estudio, para completar el protocolo redactado, y la selección de las radiografías (radiografía periapical intraoral tomada con el anillo de posicionamiento y la técnica paralela). Los pacientes del grupo estudio recibieron terapia con implantes dentales inmediatos colocados en sitios infectados, descontaminados con láser, y los del grupo control con implantes dentales con técnica tradicional. Material - Protocolo de recogida de los datos clínicos. - Material para la cirugía de implantes: set quirúrgico de aislamiento de campo y aspirador quirúrgico, guantes estériles, gorro, gafas de protección y mascarilla, jeringa de anestesia, aguja desechable de anestesia, anestesia en carpules Optocain® (Mepivacaína 1: 100.000), espejos intraorales, suero fisiológico, gasas, despegadores y separadores de campo, láser Er, Cr: YSGG Waterlase iPlus® (Biolase, Foothill Ranch, USA), set quirúrgico de implantes Straumann® (Basel, Switzerland), contraángulo y motor quirúrgico, pinzas de disección, portaagujas, hilo de sutura, tijeras, sonda y periodontal. - Biomateriales: en algunos casos se empleó una membrana absorbible (Collprotect®, Straumann®, Basel, Switzerland), Bio-Oss® (Woburn, MA, USA) y colágeno sintético (Septodont®, Mataró, España). - Procedimiento protético: set protético de implantes Straumann®, resina Duralay®, silicona, cubeta de impresión. - Material iconográfico: cámara digital NIKON® D7500 (Tokio, Japón), flash anular y espejos intraorales. - Exploración radiológica: Heliodent Plus Dentsply Sirona® y posicionador de anillos para estandarización de proyecciones XPC de Rinn® (Dentsply®, Ilinois, Francia). - Análisis radiológico: pantalla médica con una resolución de 1920 x 1080 y con aumento (7x) EIZO®. Métodos - Preparación prequirúrgica. Se realizó una anamnesis y una exploración clínica meticulosas. Se realizó una radiografía intraoral o panorámica; se solicitó una tomografía computada de haz cónico cuando fue considerado necesario por el cirujano para evaluar el volumen óseo. Se obtuvieron modelos diagnósticos para establecer un correcto diagnóstico y efectuar la planificación quirúrgica y prostodóncica. - Profilaxis antibiótica. Se pautó tratamiento con amoxicilina, 1 gr. dos veces al día durante 6 días, que se inició la noche anterior a la cirugía. Esto se realizó tanto en el grupo test como ene grupo control. - Cirugía de implantes. Para la fase quirúrgica, todos los pacientes accedieron a un plan de tratamiento que incluyó la extracción de un diente comprometido, la descontaminación del sitio con láser Er, Cr: YSGG y la colocación de un implante en la misma sesión clínica, con el fin de reemplazar el diente faltante (grupo test). Los dientes comprometidos se extrajeron de la forma más atraumática posible para proteger los tejidos circundantes, con la ayuda del láser Er, Cr: YSGG 2780 nm. El láser levantó el colgajo de espesor total con los siguientes ajustes: configuración para el modo de tejido blando, que incluía punta MC-3, longitud 9 mm, aire 20% y agua 80%. Para el tejido óseo, el modo de ajuste incluía la punta MZ-8, longitud 6 mm, aire 40% y agua 60%. Una vez que se completó la extracción, comenzó la fase de descontaminación del sitio infectado. El sitio se desbridó y descontaminó después de la extracción utilizando el mismo dispositivo láser pero con otra configuración: 2,0 W, 20% de aire y 80% de agua, mientras se montaba una punta MZ-6 de 9 mm de longitud. El tiempo de desbridamiento dependió de la cantidad de tejido patológico y del volumen óseo, la descontaminación duró de 60 a 90 segundos por alveolo, asegurando que no había contacto físico entre la punta del láser y los tejidos. El dispositivo Waterlase iPlus® (Biolase) se utilizó para todos los procedimientos con láser. Las siguientes fases de la intervención consistieron en la colocación de los implantes (Straumann®). Los implantes se colocaron con un torque mínimo de 35 N y 1 mm por debajo del pico óseo más apical. A menudo, también fue necesario colocar biomateriales para el defecto residual causado por la infección, como en este caso de ejemplo: se utilizó una membrana absorbible (Collprotect®) y Bio-Oss® para mejorar la cicatrización del tejido. En algunos casos también se utilizó colágeno sintético (Septodont®). Se colocaron suturas (PTFE 3/0 Gore®) con especial cuidado para obtener un buen reposicionamiento del colgajo. Posteriormente, se prescribió gel de gluconato de clorhexidina al 0,2% dos veces al día durante 15-20 días y se dieron instrucciones postoperatorias al paciente. Se programaron controles clínicos y radiográficos periódicos. Los pacientes del grupo de control habían seguido un protocolo de implante similar, pero la extracción del diente había tenido lugar al menos 4 meses antes y no se había realizado una descontaminación láser del sitio. - Fase protética. Los implantes se cargaron inmediatamente o después de 3 meses. En este caso los implantes no se cargaron de forma inmediata sino que la fase provisional se gestionó con un puente Maryland. La posibilidad de carga inmediata se decidió en base a algunos parámetros clínicos como la estabilidad primaria del implante de acuerdo con el paciente. - Análisis y medición de radiografías. La segunda fase de este estudio incluyó la medición de radiografías digitales por un operador ciego (R.A.) con un software específico (Imagen J, Instituto Nacional de Salud, Bethesda, Rockville, MA, EE. UU.). Para las radiografías se habían utilizado los siguientes parámetros: 65-90 kV, 7,5-10 mA y 0,22-0,25 s. Antes de la medición, se calibró cada radiografía utilizando el diámetro y la longitud del implante como medidas de referencia para corregir cualquier distorsión. Las radiografías se midieron en una pantalla médica con una resolución de 1920 x 1080 y con aumento (7x). El nivel de hueso marginal (MBL) se midió para la línea base y el seguimiento de acuerdo con Linkevicius et al., Calculando la distancia entre el cuello del implante y el primer contacto hueso-implante, y teniendo en cuenta tanto el aspecto mesial como el distal de cada implante. Para el análisis radiográfico se llevó a cabo un acuerdo intra-evaluador. Se midió una muestra independiente a priori de 20 superficies de implantes medidas dos veces, con 2 semanas de diferencia. El coeficiente de correlación intraclase bidireccional para el análisis de concordancia intra-evaluador radiográfico fue 0,97 (IC del 95% de 0,95 a 0,99). - Análisis estadístico. Como estadística descriptiva se utilizaron las desviaciones medias y estándar de las variables cuantitativas y la frecuencia y porcentajes de las variables cualitativas. Sin embargo, la unidad de análisis fue el implante, teniendo en cuenta el hecho de que a menudo se utilizaban varios implantes para cada paciente. Se utilizó un modelo estadístico mixto para la diferencia de la variable de resultado en MBL utilizando al paciente como un efecto aleatorio. La covariable fue el MBL al inicio del estudio y el grupo (implante tipo test o control) fue la variable explicativa (efecto fijo). Para comparar las diferencias al principio del estudio entre los dos grupos (implantes test versus implantes control) se utilizaron modelos de efectos mixtos para las variables cuantitativas, edad, longitud del implante, diámetro del implante, MBL al inicio del estudio. También se utilizó un modelo de efectos mixtos para comparar la duración del seguimiento entre los dos grupos. El paciente fue el efecto aleatorio (efecto aleatorio) y el grupo (tipo test o control) fue la variable explicativa (efecto fijo). Para comparar las diferencias basales entre los dos grupos (implantes tipo test vs. implantes tipo control), se utilizaron modelos multinivel para las variables cualitativas: sexo, humo, arcada (superior o inferior), área (frontales - incisivos o caninos - vs. posteriores - premolar o molar -), motivos de extracción (fractura vs. otros), presencia de absceso o fístula, presencia de lesión, implantes con cuello estrecho, carga inmediata, uso de membrana, uso de colágeno, uso de hueso sintético. Los modelos fueron a dos niveles (paciente e implante) y el grupo (implante de prueba o control) fue la variable explicativa. El umbral de significación se fijó en 0,05. Las estadísticas se realizaron con el software JMP v. 13.0 y con MLwin v. 3.05. Resultados En este estudio clínico controlado se trataron 98 pacientes con una edad promedia de 58.0 ± 14.6 años (de 21 a 88 años), 52 mujeres (53%) y 46 hombres (47%); hubo un total de 22 fumadores en la muestra (22%); el análisis retrospectivo permitió analizar un total de 149 implantes colocados, 90 (60%) fueron tipo test y 59 (40%) tipo control. Se colocaron implantes tipo test en 53 pacientes (1 implante en 35 pacientes, 2 implantes en 10 pacientes, 3 implantes en 4 pacientes, 4 implantes en 3 pacientes y 5 implantes en 1 paciente). Se colocaron implantes tipo control en 39 pacientes (1 implante en 29 pacientes, 2 implantes en 7 pacientes, 3 implantes en 3 pacientes). Se colocaron implantes tipo test y control en 6 pacientes (1 implante tipo test y 1 implante tipo control en 5 pacientes, 1 implante tipo test y 2 implantes tipo control en 1 paciente). Las variables relacionadas con la cirugía incluyen diferentes características: arcada superior o inferior, zona (anterior o posterior), motivo de la extracción (fractura, absceso o fístula), presencia y dimensión de la lesión apical, uso de implante con cuello estrecho, longitud y diámetro del implante, uso de carga inmediata, uso de membrana, colágeno o hueso sintético, medición del MBL posoperatorio. En el grupo test hubo lesiones con mayor frecuencia, la longitud del implante fue superior de aproximadamente 1 mm. La membrana y el hueso sintético se utilizaron con mayor frecuencia en el grupo test en comparación al grupo control. En particular, los motivos de la extracción en el grupo test fueron: caries (subgingivales, en dientes irrecuperables) en 32 dientes (36%), lesiones endodónticas en 10 dientes (11%), fracturas en 43 dientes (48%) y problemas periodontales (dientes con enfermedad periodontal y movilidad grado II o III) en 5 dientes (6%). En el grupo control los motivos de la exodoncia fueron: caries (subgingivales, en dientes irrecuperables) en 20 dientes (34%), lesiones endodónticas en solo 1 caso (2%), fracturas en 31 dientes (52%) y problemas periodontales (dientes con enfermedad periodontal y movilidad grado II o III) en 7 dientes (12%). Todos los implantes colocados fueron de la casa comercial Straumann®, sin embargo, estos tenían características diferentes para adaptarse a todas las situaciones clínicas. En el grupo test, se utilizaron los siguientes tipos de implantes: 33 implantes TE RN Loxim SLA Roxolid (37%), 37 implantes S RN Loxim SLA Roxolid (41%), 4 implantes SP RN Loxim SLA TiZr (4%), 3 implantes SP NNC SLAactive TiZr (3%), 4 implantes S RN SLAactive Roxolid (4%), 9 implantes SP NNC Loxim SLA Roxolid (10%). En cambio, en el grupo control, los implantes fueron: 6 TE RN Loxim SLA Roxolid (10%), 39 implantes S RN Loxim SLA Roxolid (66%), 4 implantes SP RN Loxim SLA TiZr (7%), 0 implantes SP NNC SLAactive TiZr (0%), 0 implantes S RN SLAactive Roxolid (0%), 10 implantes SP NNC Loxim SLA Roxolid (17%). El seguimiento promedio fue de 1,7 ± 0,6 años en el grupo test y 1,5 ± 0,5 años en el grupo control, con una diferencia no estadísticamente significativa (P = 0,082; modelo mixto). Solo hubo un fracaso en el grupo test (1%) y ningún fracaso en el grupo control. Se registró una complicación (mucositis) en el grupo control (2%) y ninguna aparte del fracaso en el grupo test. La diferencia en MBL entre los dos grupos fue a favor del grupo test, que incluso ganó 0,1 mm en comparación con la línea de base, mientras que el grupo de control perdió 0,1 mm en MBL. Sin embargo, la diferencia entre los dos grupos fue de solo 0,2 mm, y por lo tanto no es estadísticamente significativa (aunque si era cerca del límite P = 0,058). Discusión Objetivo del estudio El objetivo principal fue comparar los implantes post-extracción en sitios con infección y los implantes colocados con la técnica tradicional; estos últimos, se posicionaron al menos tres meses después de la exodoncia y en alvéolos sin signos de infecciones residuales. Los resultados indicaron que no había diferencia del MBL entre los dos grupos analizados. De hecho, el MBL al inicio del estudio fue de 2,4 en ambos grupos (p = 0,912). Dado que no siempre es fácil identificar la presencia de una infección activa, cuando es necesario extraer un diente comprometido, se eligieron los implantes tipo 4 para el grupo control, los cuales se colocaron en áreas edéntulas con buena cicatrización del alveolo post-extracción. Por lo tanto, en esta situación hubo menos riesgo de que siguieran permaneciendo colonias de bacterias en una zona desdentada. Resumen de los principales hallazgos Leyendo los resultados, los dos grupos parecen suficientemente homogéneos en términos de edad y sexo de los pacientes y áreas tratadas. Las opciones quirúrgicas, como la longitud del implante o el uso de biomateriales, variaron según la situación clínica. Específicamente, en el grupo test, los implantes eran más largos: la longitud del implante era mayor de aproximadamente 1 mm en el grupo test, mientras que el diámetro era muy similar en los dos grupos. Además, a excepción del colágeno, que tuvo una tasa de utilización similar en los dos grupos, la membrana y el hueso autólogo se utilizaron con mayor frecuencia en el grupo test. Esto se debe a que en el grupo test la presencia de lesiones fue más alta y, por lo tanto, los defectos óseos también se trataron con mayor frecuencia; la literatura científica también muestra que el manejo del alveolo después de la extracción a menudo requiere el uso de biomateriales para la regeneración del tejido periimplantario. Una revisión sistemática reciente muestra que el injerto óseo, llevado a cabo simultáneamente a la colocación inmediata del implante, da como resultado la preservación de las dimensiones de los tejidos duros y blandos; además, la aplicación de técnicas de regeneración ósea guiada ayuda a la preservación de los tejidos blandos y previene la reabsorción del hueso cortical vestibular del implante inmediatamente colocado, a pesar del tipo de membrana utilizada. Una radiografía antes de colocar el implante en el sitio post-extracción después de 12 o 16 semanas de cicatrización permitió comprobar la presencia de lesiones osteolíticas. Sin embargo, estudios recientes muestran que incluso después de un período adecuado de curación, pueden permanecer bacterias en el hueso que pueden afectar a la supervivencia del implante. La introducción del láser en la implantología, por lo tanto, no solo hace que la técnica inmediata de colocación del dispositivo sea más segura: la descontaminación láser también podría ser útil en la extracción de dientes con lesiones para hacer las futuras rehabilitaciones con implantes más predecibles, incluso si se realizan de manera diferida. Este estudio analizó 149 implantes en total, con mediciones de MBL mesial y distal al inicio y al seguimiento, y es por el momento el único estudio controlado en la literatura sobre la colocación de implantes en sitios infectados descontaminados con Er,Cr:YSGG 2780 láser, según el conocimiento de los autores. Además, el presente estudio incluye muchos casos llevados a cabo en los sectores posteriores, a diferencia de los muchos estudios de implantología inmediata (tipo 1) que suelen realizarse exclusivamente en áreas estéticas, donde hay menos estrés de carga masticatoria. En una revisión sistemática y un metaanálisis recientes, Lee et al. mostró la misma conclusión alentadora al analizar cinco estudios prospectivos, que no involucraban el uso de láser, sino una técnica de desbridamiento más convencional; los mismos autores informaron sobre la ausencia de estudios clínicos controlados sobre el tema en la literatura científica actual. En un estudio de Kakar et al., publicado recientemente, los autores siguieron un protocolo clínico similar al presente estudio, que incluía un desbridamiento con láser Er, Cr: YSGG 2780 nm, para tratar una serie de casos sin grupo control. Sin embargo, a pesar de que no iban a medir el MBL, el dato interesante es la supervivencia de los implantes que supera el 95% y, por tanto, está en línea con la tasa de supervivencia que se espera con las técnicas de implantología convencionales. Discusión con literatura previa Teniendo en cuenta los resultados de una Conferencia de consenso del 2017 sobre la clasificación de enfermedades y afecciones periodontales y periimplantarias, para evaluar el éxito de la terapia con implantes, es importante calcular el MBL, ya que hasta los 2 mm puede considerarse como remodelado fisiológico óseo. Otro factor que hay que considerar es la inspección visual, que demuestre la ausencia de signos de inflamación periimplantaria, con un color rosa del tejido blando y sin hinchazón; además hay que averiguar la falta de sangrado profuso (línea o gota) al sondaje. Las profundidades del sondaje pueden diferir según el biotipo del tejido blando y la ubicación del implante. Sin embargo, un aumento de la profundidad de sondaje con el tiempo sin dudas entra en conflicto con la salud periimplantaria. Los datos obtenidos sobre el MBL en esta investigación no solo están en línea y son más bajos en comparación con el grupo control, sino que también son comparables a los de los otros estudios. Entre estos, Berberi et al. describió el MBL en técnicas de carga inmediata y diferida de implantes post-extracción; también la carga inmediata parece garantizar resultados clínicos prometedores como demuestran varios casos en el presente estudio. De hecho, en el trabajo de Barbieri y cols., también se observó un MBL significativamente menor asociado con implantes cargados inmediatamente e insertados en alveolos post-extracción en comparación con la técnica de carga diferida. Por lo tanto, se rechazó la hipótesis sugerida de que se observaría un mayor MBL en los implantes cargados inmediatamente. La reformación rápida y reproducible de la mucosa periimplantaria y la salud gingival se pueden atribuir a un MBL mínimo, con aplicación inmediata de las prótesis provisionales y, por lo tanto, la ausencia de manipulación del pilar durante el período de cicatrización. En cuanto a las fases de carga y prótesis, este estudio comparó un porcentaje similar de carga inmediata entre el grupo test y el grupo de control. Esto hace que el análisis sea más completo y agregue una serie de variables que, sin embargo, no influyeron en los resultados clínicos y estadísticos. Otra motivación clínica, acerca de la mínima diferencia en el MBL de los dos grupos, puede derivar del hecho de que las técnicas regenerativas a menudo se aplicaban más a los implantes tipo 1, a causa de los defectos de hueso que se apreciaban tras la exodoncia. Ventajas, limitaciones y recomendaciones para estudios futuros Estudios anteriores que compararon radiografías panorámicas y periapicales indicaron que las periapicales eran el "Gold Standard" para medir el MBL alrededor de los implantes dentales. Un CBCT también sería útil, pero, debido a la dosis de rayos y la falta de justificación, no sería posible encontrar un número considerable de pacientes para el estudio. El examen radiográfico 3D se utilizó solo en algunos casos y se realizó muchas veces para otras necesidades clínicas. La necesidad de disponer de radiografías comparables ha implicado una escrupulosa selección de pacientes con el fin de aumentar la fiabilidad de los datos. Esto podría ser una limitación del presente estudio. En este contexto, otra limitación del presente estudio fue el número relativamente bajo de pérdidas de implantes; específicamente, debido a esto, un análisis de regresión logística de efectos aleatorios no fue significativo y, por lo tanto, los predictores potenciales registrados no podrían estar relacionados con la pérdida de implantes temprana ni tardía. Además, se trata de un estudio retrospectivo, lo que por lo tanto implica la presencia de algún sesgo, aunque con un protocolo quirúrgico ya publicado en estudios anteriores de los mismos autores. En el presente estudio, solo 10 casos tuvieron una lesión endodóntica franca; es deseable realizar estudios prospectivos solo sobre implantes colocados en sitios con lesiones endodónticas. Finalmente, otra limitación del estudio es que, en ambos grupos, se administró profilaxis antibiótica a los pacientes tratados. Esto se debe a que la evidencia científica más reciente sugiere el uso de antibióticos para prevenir infecciones sistémicas peligrosas para la salud del paciente (como la endocarditis bacteriana). Según los autores de una revisión reciente de la literatura científica, el uso de profilaxis antibiótica puede disminuir los fracasos tempranos de los implantes, pero todavía hay evidencia insuficiente para recomendar con seguridad una dosis específica. Conclusiones De la presente tesis se pueden extraer las siguientes conclusiones: I. El resultado de que no hay diferencia en MBL, que es incluso casi mejor en el grupo test, parece prometedor para incentivar la aplicación clínica del protocolo descrito para la colocación de implantes tipo 1 en sitios infectados. II. La tasa de complicaciones o fracasos es comparable entre los dos grupos y, por lo tanto, se puede afirmar que no existe un mayor riesgo en el grupo test.
- Published
- 2022
50. A clinical protocol for immediate dental implant placement in post-extraction-infected sites decontaminated with Er,Cr:YSGG laser.
- Author
-
Aiuto R, Dioguardi M, Angiero F, Peñarrocha-Diago M, Peñarrocha-Diago M, and Crippa R
- Subjects
- Humans, Esthetics, Dental, Clinical Protocols, Dental Implants adverse effects, Lasers, Solid-State therapeutic use, Peri-Implantitis
- Abstract
Background: Placement of dental implants into fresh extraction sockets offers some advantages, such as reduced treatment times and enhanced patient comfort. The Er,Cr:YSGG (Erbium, Chromium-doped: Yttrium, Scandium, Gallium, and Garnet) laser can significantly reduce bacterial concentration after the extraction of a compromised tooth. The aim of this article is to provide a clinical protocol for the management of implants placed in infected extraction sites decontaminated with Er,Cr:YSGG laser., Methods: A compromised tooth, which was an abutment for a fixed bridge, with clinical and radiological signs of infection was extracted. The infected site was treated and decontaminated with an Er,Cr:YSGG laser device (Biolase iPlus
® ) and two implants (Straumann® ) were placed in the same surgery, in order to rehabilitate the edentulous area. The intervention was completed by tissue regeneration with biomaterials., Results: Prosthetic rehabilitation after the surgical phase allowed us to provide correct function and satisfactory esthetics. In the follow-up visit, clinicians found good tissue healing and did not observe any complications, such as implant loss or peri-implantitis. The technique used in our study is repeatable and predictable, but patient selection is very important for this type of protocol as the presence of contraindications can lead to failure. The photoacoustic effect exerted by this type of laser has been proven to be effective against many pathogens. Several authors have previously demonstrated the effectiveness of this technique., Conclusions: Immediate implantation in infected sites decontaminated with Er,Cr:YSGG laser does not seem to contribute to an increased risk of failure; however, it is necessary to follow a certain set of protocols and procedures to prevent peri-implantitis and other complications.- Published
- 2024
- Full Text
- View/download PDF
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