91 results on '"Pharyngeal Residue"'
Search Results
2. Palatal augmentation prosthesis (PAP) can improve swallowing function for the patients in rehabilitation hospital
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Yoshida, Mitsuyoshi, Endo, Yuumi, Nishimura, Rumi, Masuda, Shin, Amano, Junko, and Tsuga, Kazuhiro
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- 2019
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3. Understanding user experience and normative data in pharyngeal residue rating scales used in flexible endoscopic evaluation of swallowing (FEES): A scoping review.
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Wilson, Thomas, Checklin, Martin, Lawson, Nadine, Burnett, Alissa J., Lombardo, Theresa, and Freeman-Sanderson, Amy
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ENDOSCOPY , *DEGLUTITION disorders , *REFERENCE values , *USER experience , *GREY literature - Abstract
AbstractPurposeMethodResultConclusionPharyngeal residue rating scales are often used to rate pharyngeal residue observed during flexible endoscopic evaluation of swallowing. Despite the widespread use of pharyngeal residue rating scales, there is no data that has systematically explored user experience. The aim of this scoping review was to investigate specific reporting of user experience, user centred design principles, and normative data in the development of pharyngeal residue rating scales.A scoping review was conducted across four electronic databases inclusive of all dates until June 2024. Grey literature searching occurred in March–April 2023 and was repeated in June 2024. This review followed the Preferred Reporting Items for Systematic Review and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) protocol. Titles/abstracts, full texts, and data extraction were reviewed by two independent reviewers.A total of 22 sources were included, with 18 unique pharyngeal residue rating scales identified. Two studies referred to user experience, seven included at least one user centred design principle, and four studies reported on normative data.The findings of this review highlight few pharyngeal residue rating scales include the experience of the intended user and establish normative data in the initial development phase. User experience, user centred design principles, and normative data may be useful considerations to optimise functionality. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Sliced Jelly Whole Swallowing Reduces Deglutition Risk: A Novel Feeding Method for Patients with Dysphagia.
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Aii, Seijiro, Fujishima, Ichiro, Shigematsu, Takashi, Ohno, Tomohisa, Kunieda, Kenjiro, and Yamawaki, Masanaga
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Texture modification in the form of gels or jellies is used for patients with dysphagia. For over 20 years, our group has been using gelatin jellies, a type of gel, as a starting diet for patients with dysphagia. Gelatin jellies are served in a small-sliced form and swallowed whole. In sliced jelly whole swallowing (SJWS), sliced gelatin jelly (SGJ) passes through the pharynx in one lump without collapsing. This study aimed to examine the usefulness of SJWS. We analyzed the images of videofluoroscopic swallowing studies performed using the normalized residue ratio scale (NRRSv: vallecula, NRRSp: pyriform sinus), the penetration–aspiration scale (PAS), and pharyngeal transit time (PTT) in 50 patients with dysphagia and compared the results in a prospective study. SJWS had significantly less residue in both NRRSv and NRRSp than in moderately thickened liquid swallowing. No significant differences in PAS scores were found between SGJ and moderately thickened liquid. Additionally, no significant differences in PTT scores were noted between the two. This study demonstrated the usefulness of SJWS in improving swallowing safety in patients with dysphagia. Further studies are needed to evaluate the reproducibility of the test, the comparison of SGJ with other thickened liquids, and the safety of SJWS for different diseases. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Cranial Nerve Deficits Predict Pharyngeal Phase Swallowing Impairment in Patients with Neurogenic Dysphagia: A Cross-Sectional Study: S. Nordio et al.: Cranial Nerve Deficits Predict Pharyngeal Phase Swallowing Impairment
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Nordio, Sara, Maistrello, Lorenza, Koch, Isabella, D’Imperio, Daniela, and Battel, Irene
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- 2024
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6. The Hyoid Bone Kinematics in Dysphagic Stroke Patients: Instantaneous Velocity, Acceleration and Temporal Sequence Matters.
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Chen, Shao-Yu, Wei, Kuo-Chang, Cheng, Sheng-Hao, Wang, Tyng-Guey, and Hsiao, Ming-Yen
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Hyoid bone excursion (HBE) is one of the most critical events in the pharyngeal phase of swallowing. Most previous studies focused on the total displacement and average velocity of HBE. However, HBE during swallowing is not one-dimensional, and the change of velocity and acceleration is not linear. This study aims to elucidate the relationship between the instantaneous kinematics parameters of HBE and the severity of penetration/aspiration and pharyngeal residue in patients with stroke. A total of 132 sets of video-fluoroscopic swallowing study images collected from 72 dysphagic stroke patients were analyzed. The maximal instantaneous velocity, acceleration, displacement, and the time required to reach these values in the horizontal and vertical axes were measured. Patients were grouped according to the severity of the Penetration-Aspiration Scale and the Modified Barium Swallow Impairment Profile- Pharyngeal Residue. The outcome was then stratified according to the consistencies of swallowing materials. Stroke patients with aspiration were associated with a lower maximal horizontal instantaneous velocity and acceleration of HBE, a shorter horizontal displacement, and prolonged time to maximal vertical instantaneous velocity compared to the non-aspirators. In patients with pharyngeal residue, the maximal horizontal displacement of HBE was decreased. After stratification according to bolus consistencies, the temporal parameters of HBE were more significantly associated with aspiration severity when swallowing thin bolus. Meanwhile spatial parameters such as displacement had a bigger influence on aspiration severity when swallowing viscous bolus. These novel kinematic parameters of HBE could provide important reference for estimating swallowing function and outcomes in dysphagic stroke patients. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Validation of the European Portuguese Version of the Yale Pharyngeal Severity Rating Scale
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Silva-Carvalho, Isabel, Martins, Adriana, Freitas, Susana Vaz, Teixeira, Laetitia, Meireles, Luís, and Pedroto, Isabel
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- 2024
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8. Potential of Rice-Flour Jelly Made from High-Amylose Rice as a Dysphagia Diet: Evaluation of Pharyngeal Residue by FEES.
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Tsubokawa, Misao, Fujitani, Junko, Ashida, Kanae, Hayase, Mika, Kobayashi, Namiko, Horita, Chika, Sakashita, Masafumi, Tokunaga, Takahiro, Hamano, Tadanori, Kikuta, Ken-ichiro, and Fujieda, Shigeharu
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Dysphagia diets are recommended to prevent choking and aspiration in people with dysphagia; however, rice-porridge and mashed rice-porridge, which are used as staple foods for people with dysphagia in Japan, are time-consuming to prepare. The National Agriculture and Food Research Organization has found jelly-like food products made from high-amylose rice-flour (rice-flour jelly) to be easy to prepare with a texture suitable for dysphagia diets. To investigate the potential of rice-flour jelly for the dysphagia diet, we evaluated the amount of pharyngeal residue after swallowing rice-flour jelly using fiberoptic endoscopic evaluation of swallowing and compared it with those of rice-porridge, mashed rice-porridge, and fruit jelly. We enrolled 70 participants (43 males and 27 females, aged 32–96 years, median 74.5 years) and evaluated their pharyngeal residue using the Yale Pharyngeal Residue Severity Rating Scale which includes five levels from I (none) to V (severe). Statistical analysis showed that level I was more common in fruit jelly for vallecula residue and pyriform sinus residue, and level III (mild) was more common in rice-porridge for vallecula residue (p < 0.05). No differences of pharyngeal residue were found in rice-flour jelly or mashed rice-porridge. No significant difference was observed in the number of participants with laryngeal penetration or aspiration. Therefore, rice-flour jelly is a suitable alternative to rice-porridge as a staple food for people with dysphagia in terms of food texture. [ABSTRACT FROM AUTHOR]
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- 2023
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9. Pharyngeal Residue Severity and Aspiration Risk in Stroke Patient Using Fiber-Optic Endoscopic Evaluation of Swallowing.
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Sabry, Aliaa and Abou-Elsaad, Tamer
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RESPIRATORY aspiration , *PHARYNX , *STATISTICS , *DEGLUTITION , *STROKE , *DEGLUTITION disorders , *RISK assessment , *STROKE patients , *HYPOPHARYNX , *DESCRIPTIVE statistics , *DATA analysis , *DISEASE complications ,RISK factors - Abstract
Introduction: Pharyngeal residue, defined as the material remaining in the pharynx post-swallow, is a sign of swallowing biomechanical impairment and a clinical predictor of aspiration. This study investigates the correlation between pharyngeal residue severity using the Mansoura FEES Residue Rating Scale (MFRRS) and penetration/aspiration scores using the penetration-aspiration scale (PAS) on FEES. Methods: Two hundred ten (210) swallows were obtained during standard FEES assessments of thirty patients with poststroke dysphagia. Residue, in both vallecula and the pyriform sinuses' locations, and penetration/aspiration were scored using MFRRS and PAS, respectively. The Spearman's rank-order correlation was used to assess the correlation between residue and PAS scores. The significance of the obtained results was judged at the (p < 0.05) level. Results: Significant strong positive correlations were demonstrated between PAS scores and each vallecular residue score (rs = 0.663, p = 0.000) and pyriform residue score (rs = 0.688, p = 0.001). Conclusion: There is a significant strong positive correlation between residue severity and penetration/aspiration in each anatomical site evaluated (valleculae and pyriform sinuses). Our results do not designate one site as riskier than the other because either can contribute to aspiration, but rather demonstrate penetration/aspiration to better correlate with the overall severity of the residue, perhaps as a better marker for pharyngeal inefficiency. This study offers insight into the association of residue severity with swallowing safety and efficiency. [ABSTRACT FROM AUTHOR]
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- 2023
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10. Validation and Cultural Adaptation of an Arabic Version of Pediatric Eating Assessment Tool (Pedi-EAT-10Arabic).
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Adel, Sally M., Gaafar, Alaa H., Fasseeh, Nader, Abdou, Rania M., and Hamouda, Nesrine Hazem
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Pediatric eating assessment tool (Pedi-EAT-10
Arabic ) is a validated and reliable caregiver administered outcome instrument designed for detection of children at high risk of penetration/aspiration. The objective of this study is to translate and validate the Arabic version of Pedi-EAT-10 and to correlate its results with pharyngeal residue and aspiration on fiber optic endoscopic examination of swallowing (FEES). A cross-sectional study including 202 children selected randomly from those attending the swallowing clinic in phoniatrics unit, Otorhinolaryngology department (ORL) at main university hospital between February 2019 and October 2020 complaining of dysphagia. For test–retest reliability, one hundred caregivers refilled the Pedi-EAT-10Arabic after a 2-week period following their first visit. Validity was established by comparing the scores of dysphagia patients to healthy controls. Internal consistency of Pedi-EAT-10Arabic was high (Cronbach's alpha 0.986). Intra class correlation showed excellent test–retest reliability (r = 0.968). The median Pedi-EAT 10Arabic score was significantly higher in dysphagia group compared to healthy controls. (Median 27 IQR 21–34 for cases compared to median zero IQR 0–2 points for healthy controls, P less than 0.001). A strong correlation was found between Pedi-EAT 10Arabic scores and PAS scores with Spearman's correlation coefficient r = 0.803 and P < 0.001. The ROC for evaluating the discriminatory capacity of Pedi-EAT 10 for aspiration showed an AUC of 0.92 (95% CI of 0.89 to 0.96). Conclusion: Pedi-EAT 10Arabic was found to be a valid and reliable screening tool for further instrumental assessment of risk of dysphagia in pediatric population. [ABSTRACT FROM AUTHOR]- Published
- 2022
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11. Validity and Reliability of the Turkish Translation of the Yale Pharyngeal Residue Severity Rating Scale.
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Atar, Yavuz, Atar, Sevgi, Ilgin, Can, Anarat, Melis Ece Arkan, Uygan, Ugur, and Uyar, Yavuz
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This study aimed to assess the validity and reliability of the Turkish translation of the Yale pharyngeal residue severity rating scale. The scale measures the severity of residue in the vallecula and pyriform sinus. The original scale was translated into Turkish by two bilingual English-Turkish translators, and the Turkish version was translated back into English by two qualified professional translators to assess accuracy. The evaluators were divided into two groups (training and no-training) and two subgroups according to their experience. Intra-rater, inter-rater, and intra-class correlation coefficient measurements were analyzed by calculating agreement rates, kappa, and p values. In the analysis of the reliability, intra-class correlation coefficient values in the overall ratings for both the vallecula and the pyriform sinus were 0.9996 (95% CI 0.9992–0.9998) and 0.9997 (95% CI 0.9995–0.9999), respectively (p < 0.01). High agreement (> 95%) and perfect Fleiss kappa values were obtained for the vallecula and pyriform sinus ratings in the inter-rater initial assessments (κ = 0.959 and κ = 0.967, respectively). Perfect kappa values were found in the intra-rater results for both the vallecula and pyriform sinus (α = 0.9959 and κ = 0.9959, respectively). In the inter-rater secondary analysis, the vallecula and pyriform sinus kappa values were perfect (κ = 0.959 and κ = 0.967, respectively). In the intra-rater analysis, perfect kappa values were obtained for the vallecula and pyriform sinus in the no-training group and less-experience subgroup (κ = 0.9918 and κ = 1.0 for the vallecula, and κ = 1.0 and κ = 0.9902 for the pyriform sinus, respectively) In the inter-rater analysis, perfect kappa values were obtained for the vallecula and pyriform sinus in the no-training group and less-experience subgroup (κ = 0.9507 and κ = 0.9606 for the vallecula, and κ = 0.9836 and κ = 1.0 for the pyriform sinus, respectively). The Turkish translation of the Yale pharyngeal residue severity rating scale demonstrated high validity and reliability scores in determining pharyngeal residue location and value in the fiberoptic endoscopic evaluation of swallowing. [ABSTRACT FROM AUTHOR]
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- 2022
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12. Effect of dentures on pharyngeal swallowing function in patients with dysphagia.
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Takagi, Daisuke, Ohno, Tomohisa, Moriwaki, Motoki, Katagiri, Norimasa, Umeda, Yoshiko, Tohara, Haruka, Nomoto, Akiko, and Fujishima, Ichiro
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PHARYNX , *STATISTICS , *DENTURES , *DEGLUTITION , *CLINICAL trials , *DEGLUTITION disorders , *EDENTULOUS mouth , *FISHER exact test , *FLUOROSCOPY , *COMPARATIVE studies , *T-test (Statistics) , *DESCRIPTIVE statistics , *HYPOPHARYNX , *DATA analysis , *KINEMATICS - Abstract
Aim: Dentures play an important role in improving masticatory and oropharyngeal swallowing functions in some edentulous patients without dysphagia. However, few studies have been conducted on patients with dysphagia. This study investigated the effect of dentures on pharyngeal swallowing function in patients with dysphagia. Methods: Older inpatients with dysphagia who used well‐fitting dentures were included in the study. Videofluoroscopic swallowing study findings with and without dentures were compared. Pharyngeal residue and area as spatial, the distance between the maxilla and mandible, hyoid bone/laryngeal displacement, and upper esophageal sphincter opening as kinematics, oral/pharyngeal transit time as temporal measurements, and patient‐reported symptoms were evaluated. The primary outcome was the pharyngeal residue measured using the normalized residue ratio scale. Comparisons were made using the paired t‐test, Wilcoxon signed‐rank test and Fisher's exact test. Results: The mean age of the 27 participants was 86.1 ± 6.8 years. The vallecular residue was more in those without dentures (with dentures: 0.01 [0–0.02], without dentures: 0.03 [0–0.08]; P = 0.003). The pyriform sinus residue showed no significant difference. Denture removal significantly increased the pharyngeal area. The distance between the maxilla and mandible decreased in the absence of dentures, and other kinematic measurements showed no significant differences. Oral/pharyngeal transit time was prolonged without dentures. Conclusions: Morphological changes caused by the removal of dentures led to pharyngeal expansion, which may result in increased vallecular residue. A treatment plan that considers the effect of dentures on pharyngeal swallowing function may provide rehabilitation that is more effective. Geriatr Gerontol Int 2021; 21: 907–912. [ABSTRACT FROM AUTHOR]
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- 2021
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13. Validation and Cultural Adaptation of an Arabic Version of Pediatric Eating Assessment Tool (Pedi-EAT-10Arabic)
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Adel, Sally M., Gaafar, Alaa H., Fasseeh, Nader, Abdou, Rania M., and Hamouda, Nesrine Hazem
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- 2022
- Full Text
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14. Correlation of Pharyngeal Residue with Penetration-Aspiration in Post-Radiotherapy Nasopharyngeal Carcinoma Patients with Oropharyngeal Dysphagia.
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Paramita, Dionisia Vidya, Juniati, Sri Herawati, and Romdhoni, Achmad Chusnu
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RESPIRATORY aspiration -- Risk factors ,PHARYNX ,STATISTICS ,DEGLUTITION disorders ,CANCER patients ,DESCRIPTIVE statistics ,DATA analysis ,NASOPHARYNX tumors ,ENDOSCOPY ,DISEASE complications - Abstract
Background: Nasopharyngeal carcinoma (NPC) ranks first for head and neck malignancies, and radiotherapy is a recommended treatment. Most post-radiotherapy NPC patients experience oropharyngeal dysphagia that results in pharyngeal residue. Pharyngeal residue is thought to be a risk factor for aspiration-penetration. Objective: Examining the correlation between pharyngeal residue and penetration-aspiration in post-radiotherapy NPC patients. Method: Participants have been identified since 2018 to find out the total number of NPC patients. In the period January-October 2019, identifcation of NPC patients was performed according to participant criteria. Participants were examined for fberoptic endoscopic evaluation of swallowing (FEES), pharyngeal residue using the Yale Pharyngeal Residue Severity Rating Scale (YPR-SRS), and penetration-aspiration using Penetration-Aspiration Scale (PAS). Statistical tests were used Spearman correlation test with p<0.05. Results: The highest participant's pharyngeal residue appeared in vallecula when given soft bolus (96.55%), and in pyriform sinus when given thick liquid bolus (72.41%). Most participants with soft bolus had the highest negative penetration (72.59%) and positive penetration in thick liquid bolus (51.72%), while most had negative aspirations with the lowest value (89.66%). There is aspiration in 10.34% of patients when given a dilute liquid. There was a significant correlation between pharyngeal residue in vallecula and pyriform sinus with penetration-aspiration (p<0.05). There was a positive association with the use of soft bolus (r=0.623), thick liquid bolus (r=0.631), and dilute liquid bolus (r=0.891). Conclusions: There is a significant association between pharyngeal residue and penetration-aspiration in post-radiotherapy NPC patients. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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15. Residue Ratings on FEES: Trends for Clinical Application of Residue Measurement.
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Pisegna, Jessica M., Kaneoka, Asako, Coster, Wendy J., Leonard, Rebecca, and Langmore, Susan E.
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Considering that measurement is a critical part of diagnostic technique for evaluating swallowing dysfunction, there is a need for a better foundational understanding of what influences residue measurement on flexible endoscopic evaluation of swallowing (FEES). This study investigated two factors and their potential influence on trends in residue ratings on FEES: (1) bolus consistency, and (2) residue severity levels on two different types of rating scales. Thirty-three clinicians were asked to rate their overall impressions of pharyngeal residue on 75 FEES videos representing a wide range of residue severities for thin liquid, applesauce, and cracker boluses. Ratings were made on both a visual analog scale (VAS) and a five-point ordinal scale in a randomized fashion across two sessions about two weeks apart. Statistical correlations were determined to assess the association between residue ratings and severity levels and bolus consistency. A total of 2475 VAS ratings and 2473 ordinal ratings were collected. Residue ratings were statistically different depending on severity level (p < 0.0001) and bolus consistency (p < 0.004). Raters appeared to avoid rating at the severe end of the scales, especially on visual analog scales. This study documented the relationship between clinician ratings of pharyngeal residue on FEES and various factors like severity and bolus type. Other findings, such as differences in ratings depending on the type of rating scale and halo effects on the VAS, are valuable for future scale development for understanding perceptual ratings of residue on FEES. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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16. Estimation of pharyngeal residue after swallowing by retronasal aroma.
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Okawa, Jumpei, Hori, Kazuhiro, Fujiwara, Shigehiro, Uehara, Fumiko, Shitara, Satoko, Kodama, Shohei, and Ono, Takahiro
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NOSE physiology , *DEGLUTITION , *FOOD , *SMELL , *TRACHEA intubation - Abstract
Background: Pharyngeal residue can trigger aspiration and choking after swallowing. Various studies to assess the amount of pharyngeal residue have been conducted; however, an easy and quantitative method is yet to be established. The aroma released from the pharyngeal residue is thought to be delivered from the pharynx to the nasal cavity via velopharynx by expiration, that is, retronasal pathway. Objective: This study verified that the amount of pharyngeal residue could be estimated by aroma intensity. Methods: Ten healthy adult subjects had tubes in from the oral cavity to the pharynx. Varying amounts of essence were dispensed into the pharynx through the tube either at rest or after swallowing the essence. Pharyngeal residue was simulated by retention essence in the pharynx without swallowing. An odour sensor was placed in the nostril, and the aroma intensity of the retained essence was measured over time. Results: The aroma intensity level flattened after a certain period of time had elapsed, and a significant correlation was found between the amount of essence dispensed and the flattened aroma intensity, both at rest and after swallowing. Furthermore, to estimate in a short period of time, changes in aroma intensity over time were estimated by fitting to a decay curve. The estimated intensity at convergence, calculated from the fitted curve from 80 to 120 seconds after swallowing, was significantly correlated to the measured intensity. Conclusion: The amount of pharyngeal residue can be estimated in a short period of time by measuring the aroma intensity. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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17. A computational fluid dynamics simulation of liquid swallowing by impaired pharyngeal motion: bolus pathway and pharyngeal residue.
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Jun Ohta, Shunichi Ishida, Tetsuaki Kawase x, Tetsuaki Kawase, Yukio Katori, and Yohsuke Imai
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COMPUTATIONAL fluid dynamics , *BOLUS (Digestion) , *MOTION , *DEGLUTITION , *VISCOSITY - Abstract
Common practices to improve the ability to swallow include modifying physical properties of foods and changing the posture of patients. Here, we quantified the effects of the viscosity of a liquid bolus and patient posture on the bolus pathway and pharyngeal residue using a computational fluid dynamics simulation. We developed a computational model of an impaired pharyngeal motion with a low pharyngeal pressure and no pharyngeal adaptation. We varied viscosities from 0.002 to 1 Pa·s and postures from 15° to 30° (from nearly vertical to forward leaning). In the absence of pharyngeal adaptation, a honey-like liquid bolus caused pharyngeal residue, particularly in the case of forward-leaning postures. Although the bolus speed was different among viscosities, the final pathway was only slightly different. The shape, location, and tilting of the epiglottis effectively invited a bolus to two lateral pathways, suggesting a high robustness of the swallowing process. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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18. Association Between Laryngeal Sensation, Pre-swallow Secretions and Pharyngeal Residue on Fiberoptic Endoscopic Examination of Swallowing.
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Shapira-Galitz, Yael, Shoffel-Havakuk, Hagit, Halperin, Doron, and Lahav, Yonatan
- Abstract
Reduced laryngeal sensation and accumulated pharyngeal secretions are known predictors of aspiration. Yet, their association with residue has not been fully explored. One Hundred and ten fiberoptic endoscopic examination of swallowing (FEES) examinations were retrospectively analyzed. Murray's secretion scale (MSS) for secretion stasis and laryngeal sensation were tested for association with residue severity (Yale pharyngeal residue severity rating scale, YPR-SRS) and the number of swallows required to clear the bolus. The bolus challenges of each consistency (liquid, purée and solid) with the highest PAS and YPR-SRS scores were analyzed. Impaired laryngeal sensation (ILS) and MSS were both independently significantly associated with higher YPR-SRS for all consistencies examined. Mean YPR-SRS for patients with both ILS and secretion stasis was respectively 2.4 ± 1.1, 2.5 ± 1.2, 2.4 ± 1.2 for liquid, purée and solids in the vallecula, and 2.9 ± 1.3, 2.3 ± 1.1, 2 ± 1 for pyriform sinuses residue compared to 1.8 ± 0.7, 1.6 ± 1, 1.6 ± 1 for vallecular residue and 1.8 ± 0.8, 1.4 ± 0.8, 1.3 ± 0.7 for pyriform sinus residue of patients with normal laryngeal sensation and no stasis (p < 0.05 for all except liquids in vallecula). The combined findings of both ILS and MSS ≥ 1 had a sensitivity of 25.9%, specificity of 94.2%, positive predictive value (PPV) of 83.3% and negative predictive value (NPV) of 53.3% for prediction of pharyngeal residue and a sensitivity of 58.3%, specificity of 88.8%, PPV of 39.9% and a NPV of 94.6% for prediction of aspiration. Both ILS and MSS were significantly associated with increased number of swallows required to clear a bolus. Abnormal laryngeal sensation and secretion stasis are associated with pharyngeal residue severity and reduced residue clearing on FEES. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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19. Validation of the German Version of the Yale Pharyngeal Residue Severity Rating Scale.
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Gerschke, Marco, Schöttker-Königer, Thomas, Förster, Annette, Netzebandt, Jonka Friederike, and Beushausen, Ulla Marie
- Abstract
The aim of this study was to validate the German Version of the Yale Pharyngeal Residue Severity Rating Scale and to investigate the impact of rater experience and training. The English original scale was translated into German language using a forward-backward method. For the validation, 30 images of different pharyngeal residue amounts have been selected and assigned to the scales' severity levels by two experts. 28 raters rated the images in randomized order in two passes. To investigate the impact of experience and training, raters were grouped into subgroups. Statistical analysis was carried out using kappa statistics. The results demonstrate excellent residue ratings for construct validity, inter-rater reliability and intra-rater reliability regarding overall group and all subgroups (Kappa > 0.90). No significant differences were found between groups by experience and inconstant differences were found between groups by training. The German version of the Yale Pharyngeal Residue Severity Rating Scale is a valid, reliable instrument for scoring location and severity of pharyngeal residue in the context of flexible endoscopic evaluations of swallowing. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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20. Does the Hebrew Eating Assessment Tool-10 Correlate with Pharyngeal Residue, Penetration and Aspiration on Fiberoptic Endoscopic Examination of Swallowing?
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Shapira-Galitz, Yael, Yousovich, Ruth, Halperin, Doron, Wolf, Michael, Lahav, Yonatan, and Drendel, Michael
- Abstract
The Eating Assessment Tool-10 (EAT-10) is a 10-item patient-reported outcome measure (PROM) for dysphagia patients. The objective of this study was to translate and validate the EAT-10Heb and to test for a correlation between its score and residue, penetration and aspiration on Fiberoptic Endoscopic Examination of Swallowing (FEES). 136 patients visiting two specialized dysphagia clinics and undergoing FEES between April 2015 and August 2017, filled the EAT-10Heb. 23 patients refilled the EAT-10Heb during a 2-week period following their first visit. FEES were scored for residue (1 point per consistency, maximum 3 points) and penetration and aspiration (1 point for penetration, 2 points for aspiration per consistency, maximum 6 points). 51 healthy volunteers also filled the EAT-10Heb. Internal consistency and test-retest reproducibility were examined for reliability testing. Validity was established by comparing EAT-10Heb scores of dysphagia patients to healthy controls. The EAT-10Heb score was then correlated with the FEES score. Internal consistency of the EAT-10Heb was high (Cronbach's alpha = 0.925) as was the test-retest reproducibility (Spearman's correlation coefficient = 0.82, p < 0.0001). The median EAT-10Heb score was significantly higher in the dysphagia group compared to healthy controls (13, IQR 7-22 points for dysphagia patients compared to 0, IQR 0-0 points for healthy controls, p < 0.0001). A weak correlation was found between the EAT-10Heb scores and the FEES score (Pearson's correlation coefficient = 0.376, p < 0.0001). While the EAT-10Heb was found to be a reliable and valid PROM, it only weakly correlates with the pathological findings on FEES examination. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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21. Reliability of Untrained and Experienced Raters on FEES: Rating Overall Residue is a Simple Task.
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Pisegna, Jessica M., Borders, James C., Kaneoka, Asako, Coster, Wendy J., Leonard, Rebecca, and Langmore, Susan E.
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COMPARATIVE studies ,DEGLUTITION ,DEGLUTITION disorders ,ENDOSCOPY ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,RESEARCH evaluation ,VIDEO recording ,EVALUATION research ,RESEARCH bias - Abstract
The purpose of this study was to investigate the reliability of residue ratings on Fiberoptic Endoscopic Evaluation of Swallowing (FEES). We also examined rating differences based on experience to determine if years of experience influenced residue ratings. A group of 44 raters watched 81 FEES videos representing a wide range of residue severities for thin liquid, applesauce, and cracker boluses. Raters were untrained on the rating scales and simply rated their overall impression of residue amount on a visual analog scale (VAS) and a five-point ordinal scale in a randomized fashion across two sessions. Intra-class correlation coefficients, kappa coefficients, and ANOVAs were used to analyze agreement and differences in ratings. Residue ratings on both the VAS and ordinal scales had acceptable inter- and intra-rater reliability. Inter-rater agreement was acceptable (ICC > 0.7) for all comparisons. Intra-rater agreement was excellent on the VAS scale (rc = 0.9) and good on the ordinal scale (k = 0.78). There was no significant difference between expert ratings and other raters based on years of experience for cracker ratings (p = 0.2119) and applesauce ratings (p = 0.2899), but there was a significant difference between clinicians on thin liquid ratings (p = 0.0005). Without any specific training, raters demonstrated high reliability when rating the overall amount of residue on FEES. Years of experience with FEES did not influence residue ratings, suggesting that expert ratings of overall residue amount are not unique or specialized. Rating the overall amount of residue on FEES appears to be a simple visual-perceptual task for puree and cracker boluses. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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22. Rethinking Residue: Determining the Perceptual Continuum of Residue on FEES to Enable Better Measurement.
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Pisegna, Jessica M., Kaneoka, Asako, Leonard, Rebecca, and Langmore, Susan E.
- Abstract
The goal of this work was to better understand perceptual judgments of pharyngeal residue on flexible endoscopic evaluation of swallowing (FEES) and the influence of a visual analog scale (VAS) versus an ordinal scale on clinician ratings. The intent was to determine if perceptual judgments of residue were more accurately described by equal or unequal intervals. Thirty-three speech language pathologists rated pharyngeal residue from 75 FEES videos representing a wide range of residue severities for thin liquid, applesauce, and cracker boluses. Clinicians rated their impression of the overall residue amount in each video on a VAS and, in a different session, on a five-point ordinal scale. Residue ratings were made in two separate sessions separated by several weeks. Statistical correlations of the two rating methods were carried out and best-fit models were determined for each bolus type. A total of 2475 VAS ratings and 2473 ordinal ratings were collected. Residue ratings from both methods (VAS and ordinal) were strongly correlated for all bolus types. The best fit for the data was a quadratic model representing unequal intervals, which significantly improved the r 2 values for each bolus type (cracker r 2 = 0.98, applesauce r 2 = 0.99, thin liquid r 2 = 0.98, all p < 0.0001). Perceptual ratings of pharyngeal residue demonstrated a statistical relationship consistent with unequal intervals. The present findings support the use of a VAS to rate residue on FEES, allowing for greater precision as compared to traditional ordinal rating scales. Perceptual judgments of pharyngeal residue reflected unequal intervals, an important concept that should be considered in future rating scales. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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23. Effects of Tablet Size and Head Posture on Drug Swallowing: A Preliminary Examination Using Endoscopy in Healthy Subjects
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Shuntaro, Sugiyama, Takatoshi, Iida, Yoshinari, Morimoto, Yuki, Yamazaki, Lou, Mikuzuki, and Megumi, Hayashi
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Adult ,Male ,Posture ,pharyngeal residue ,head posture ,Healthy Volunteers ,tablet size ,Deglutition ,otorhinolaryngologic diseases ,Humans ,Female ,endoscopy ,swallowing ,Tablets - Abstract
Tablet size and head posture have been reported to affect swallowing of medications, but no previous studies have evaluated their effects in detail. Our aim was to investigate for the first time the effect of tablet size and head posture on drug swallowing by endoscopic evaluation in healthy subjects. Round tablets (7 , 10 , 12, and 14 mm in diameter) were swallowed by 15 healthy adults with an endoscope inserted in the neutral, head flex-ion, and head extension positions. Evaluation of swallowing difficulty using a numeric rating scale (NRS), presence or absence of pharyngeal residue and its location, and tablet oral transit time (TOTT) were recorded. In the neutral position, the NRS score was higher with the 14 mm tablets than with the 7 mm tablets. The TOTT with the 7 mm tablets was significantly shorter in the head extension than in the neutral position. Swallowing difficulty increased when the tablet diameter was more than 7 mm. Residues were found in the epi-glottis, pyriform sinus, and tongue base. These findings suggest that head extension shortens the TOTT and assists oral-pharyngeal transport.
- Published
- 2021
24. Effects of carbonation of liquids on penetration–aspiration and residue management
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Binhuan Wang, Audrey Levy, Yael Shapira-Galitz, Dina Shpunt, Ory Madgar, Michael Wolf, Michael Drendel, and Yan Zhang
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Male ,FEES ,Carbonation ,Laryngology ,Swallowing ,Vallecula ,Medicine ,Humans ,Pharyngeal Residue ,Residue (complex analysis) ,business.industry ,Endoscopy ,General Medicine ,Dysphagia ,Respiration Disorders ,Deglutition ,Aspiration ,medicine.anatomical_structure ,Residue ,Cross-Sectional Studies ,Otorhinolaryngology ,Anesthesia ,Head and neck surgery ,Female ,medicine.symptom ,business ,Deglutition Disorders - Abstract
Objective Carbonation as a sensory enhancement strategy for prevention of aspiration of thin liquids has not been thoroughly studied. The aim of our study was to examine the effect of carbonation on penetration–aspiration and pharyngeal residue in dysphagia patients using Fiber-Optic Endoscopic Evaluation of Swallowing (FEES) and to identify parameters associated with a response to carbonation. Methods A cross-sectional study of patients undergoing FEES in a dysphagia clinic. Patients were offered 100 cc of dyed water. Penetration–aspiration was scored using the penetration–aspiration scale (PAS). Residue was scored using the Yale Pharyngeal Residue Severity Rating Scale (YPR-SRS). Patients with a PAS ≥ 2 for water were subsequently offered 100 cc of carbonated water. PAS, YPR-SRS and residue clearance were compared between thin and carbonated liquids. Multivariate logistic regression analysis was used to identify predictors for good response to carbonation. Results 84 patients were enrolled, 77.4% males, with diverse dysphagia etiologies (58.3% neurogenic, 11.9% radiation-induced, 23.8% deconditioning-induced, and 6% neck surgery induced). Median PAS was 7 (IQR 4–8) for thin liquids and 4.5 (IQR 2–8) for carbonated liquids (P = 0.0001). YPR-SRS was reduced for carbonated compared to thin liquids in the vallecula (1.58 ± 0.83 vs 1.76 ± 0.93, P = 0.001) and piriform sinuses (1.5 ± 0.87 vs 1.67 ± 0.9, P = 0.002). 31 patients had improvement in PAS with carbonation. Deconditioning as a dysphagia etiology was found to predict good response to carbonation on multivariate logistic regression analysis. Conclusion Carbonation may prevent aspiration and improve residue management for some patients with dysphagia for liquids. Level of evidence IV.
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- 2021
25. Mechanisms of Impaired Swallowing on Thin Liquids Following Radiation Treatment for Oropharyngeal Cancer
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Andrew Hope, Carly E. A. Barbon, Ashley A. Waito, Douglas B. Chepeha, Catriona M. Steele, and Melanie Peladeau-Pigeon
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Male ,Linguistics and Language ,Laryngeal vestibule ,medicine.medical_treatment ,Language and Linguistics ,030507 speech-language pathology & audiology ,03 medical and health sciences ,Speech and Hearing ,0302 clinical medicine ,Swallowing ,medicine ,otorhinolaryngologic diseases ,Speech ,Humans ,030223 otorhinolaryngology ,Pharyngeal Residue ,Research Articles ,business.industry ,Head and neck cancer ,digestive, oral, and skin physiology ,Cancer ,medicine.disease ,Dysphagia ,Deglutition ,Radiation therapy ,Oropharyngeal Neoplasms ,medicine.anatomical_structure ,Barium ,Anesthesia ,Vestibule ,Fluoroscopy ,medicine.symptom ,Larynx ,0305 other medical science ,business ,Deglutition Disorders - Abstract
Purpose Dysphagia is one of the most debilitating chronic symptoms experienced by patients who undergo radiation treatment for head and neck cancer. Despite the high prevalence of dysphagia in patients with head and neck cancer, we lack understanding of the specific changes in swallowing physiology that arise in the short-term following radiation therapy and how these changes impact the key functions of swallowing safety and efficiency. This study sought to identify pathophysiological mechanisms underlying impairments in swallowing safety and efficiency on thin liquids following (chemo)radiation for oropharyngeal cancer. Method Videofluoroscopic swallowing studies were completed in 12 male patients within 6 months following completion of (chemo)radiation and in 12 healthy male controls. To compare swallowing function and physiology between groups, we analyzed three discrete sips of 20% w/v thin liquid barium per participant. The videofluoroscopic swallowing study recordings were rated for swallowing safety, efficiency, timing parameters, and pixel-based measures of structural area or movement. Results The oropharyngeal cancer cohort displayed significantly higher frequencies of penetration–aspiration, incomplete laryngeal vestibule closure, prolonged time-to-laryngeal vestibule closure, and poor pharyngeal constriction. Incomplete or delayed laryngeal vestibule closure was associated with airway invasion, while poor pharyngeal constriction was associated with pharyngeal residue. Conclusions This study highlights the primary mechanisms behind impaired safety and efficiency of the swallow in patients following (chemo)radiation for oropharyngeal cancer.
- Published
- 2020
26. A Cross-Sectional, Quantitative Videofluoroscopic Analysis of Swallowing Physiology and Function in Individuals With Amyotrophic Lateral Sclerosis
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Carly E. A. Barbon, Emily K. Plowman, Kelby Magennis, Lauren Tabor-Gray, Catriona M. Steele, Melanie Peladeau-Pigeon, Raele Robison, and Ashley A. Waito
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Adult ,Linguistics and Language ,Laryngeal vestibule ,Physiology ,Language and Linguistics ,Constriction ,Speech and Hearing ,Swallowing ,Medicine ,Fluoroscopy ,Speech ,Humans ,Amyotrophic lateral sclerosis ,Pharyngeal Residue ,Research Articles ,medicine.diagnostic_test ,business.industry ,Cineradiography ,Disease progression ,digestive, oral, and skin physiology ,Amyotrophic Lateral Sclerosis ,medicine.disease ,Deglutition ,medicine.anatomical_structure ,Cross-Sectional Studies ,Pharynx ,Bolus (digestion) ,business ,Deglutition Disorders - Abstract
Purpose To date, research characterizing swallowing changes in individuals with amyotrophic lateral sclerosis (ALS) has primarily relied on subjective descriptions. Thus, the degree to which swallowing physiology is altered in ALS, and relationships between such alterations and swallow safety and/or efficiency are not well characterized. This study provides a quantitative representation of swallow physiology, safety, and efficiency in a sample of individuals with ALS, to estimate the degree of difference in comparison to published healthy reference data and identify parameters that pose risk to swallow safety and efficiency. Secondary analyses explored the therapeutic effect of thickened liquids on swallowing safety and efficiency. Method Nineteen adults with a diagnosis of probable-definite ALS (El-Escorial Criteria–Revised) underwent a videofluoroscopic swallowing study, involving up to 15 sips of barium liquid (20% w/v), ranging in thickness from thin to extremely thick. Blinded frame-by-frame videofluoroscopy analysis yielded the following measures: Penetration–Aspiration Scale, number of swallows per bolus, amount of pharyngeal residue, degree of laryngeal vestibule closure (LVC), time-to-LVC, duration of LVC (LVCdur), pharyngeal area at maximum constriction, diameter of upper esophageal sphincter opening, and duration of UES opening (UESOdur). Measures of swallow physiology obtained from thin liquid trials were compared against published healthy reference data using unpaired t tests, chi-squared tests, and Cohen’s d effect sizes (adjusted p < .008). Preliminary relationships between parameters of swallowing physiology, safety, and efficiency were explored using nonparametric Cochrane’s Q, Friedman’s test, and generalized estimating equations ( p < .05). Results Compared to healthy reference data, this sample of individuals with ALS displayed a higher proportion of swallows with partial or incomplete LVC (24% vs. < 1%), increased time-to-LVC ( d = 1.09), reduced UESwidth ( d = 0.59), enlarged pharyngeal area at maximum constriction, prolonged LVCdur ( d = 0.64), and prolonged UESOdur ( d = 1.34). Unsafe swallowing (i.e., PAS ≥ 3) occurred more frequently when LVC was partial/incomplete or time-to-LVC was prolonged. Pharyngeal residue was associated with larger pharyngeal areas at maximum constriction. Unsafe swallowing occurred less frequently with extremely thick liquids, compared to thin liquids. No significant differences in pharyngeal residue were observed based on liquid thickness. Conclusions Quantitative videofluoroscopic measurements revealed moderate-to-large differences in swallow physiology between this sample of individuals with ALS and healthy reference data. Increased time-to-LVC, noncomplete LVC, and enlarged pharyngeal area at maximum constriction were associated with impaired swallow safety or efficiency. Thickened liquids may mitigate the risk of acute episodes of aspiration in individuals with ALS. Further work is needed to corroborate these preliminary findings and explore how swallowing profiles evolve throughout disease progression.
- Published
- 2020
27. Relationship between videofluoroscopic and subjective (physician- and patient- rated) assessment of late swallowing dysfunction after (chemo) radiation: Results of a prospective observational study
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Hans Paul van der Laan, Rico N Rinkel, Johannes A. Langendijk, Nathalie Perdok, Irma M. Verdonck-de Leeuw, A. Gawryszuk, Hendrik P. Bijl, Jan Wedman, Johanna G M van den Hoek, Arjen van der Schaaf, Roel J H M Steenbakkers, Guided Treatment in Optimal Selected Cancer Patients (GUTS), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), CCA - Cancer Treatment and quality of life, APH - Personalized Medicine, APH - Mental Health, Otolaryngology / Head & Neck Surgery, and CCA - Imaging and biomarkers
- Subjects
medicine.medical_specialty ,EUROPEAN-ORGANIZATION ,ASPIRATION ,THERAPY ,TOXICITY ,Videofluoroscopy ,Swallowing ,NECK-CANCER ,QUALITY-OF-LIFE ,Physicians ,Internal medicine ,medicine ,otorhinolaryngologic diseases ,Humans ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,HEAD ,Stage (cooking) ,Pharyngeal Residue ,Head and neck cancer ,business.industry ,INTENSITY ,Swallowing Disorders ,(Chemo)radiation ,Hematology ,Dysphagia ,medicine.disease ,Deglutition ,Oncology ,Quality of Life ,Observational study ,medicine.symptom ,Deglutition Disorders ,Choking ,business ,RADIOTHERAPY - Abstract
BACKGROUND AND PURPOSE: Primary (chemo)radiation (CHRT) for HNC may lead to late dysphagia. The purpose of this study was to assess the pattern of swallowing disorders based on prospectively collected objective videofluoroscopic (VF) assessment and to assess the correlations between VF findings and subjective (physician- and patient-rated) swallowing measures.MATERIAL AND METHODS: 189 consecutive HNC patients receiving (CH)RT were included. Swallowing evaluation at baseline and 6 months after treatment (T6) encompassed: CTCAE v.4.0 scores (aspiration/dysphagia), PROMs: SWAL QOL/ EORTC QLQ-H&N35 (swallowing domain) questionnaires and VF evaluation: Penetration Aspiration Scale, semi-quantitative swallowing pathophysiology evaluation, temporal measures and oral/pharyngeal residue quantification. Aspiration specific PROMs (aPROMs) were selected. Correlations between late penetration/aspiration (PA_T6) and: clinical factors, CTCAE and aPROMs were assessed using uni- and multivariable analysis.RESULTS: Prevalence of PA increased from 20% at baseline to 43% after treatment (pCONCLUSION: The risk of RT-induced PA is substantial. Presented prediction models for late penetration/aspiration may support patient selection for baseline and follow-up VF examination. Furthermore, all aspiration related OARs involved in aforementioned swallowing components should be addressed in swallowing sparing strategies. The dose to these structures as well as baseline PROMs should be included in future NTCP models for aspiration.
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- 2021
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28. Pharyngeal Residue Severity Rating Scales Based on Fiberoptic Endoscopic Evaluation of Swallowing: A Systematic Review.
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Neubauer, Paul, Hersey, Denise, Leder, Steven, Neubauer, Paul D, Hersey, Denise P, and Leder, Steven B
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CINERADIOGRAPHY ,DEGLUTITION ,DEGLUTITION disorders ,ESOPHAGOSCOPY ,FIBER optics ,FLUOROSCOPY ,PHARYNX ,SYSTEMATIC reviews ,SEVERITY of illness index - Abstract
Identification of pharyngeal residue severity located in the valleculae and pyriform sinuses has always been a primary goal during fiberoptic endoscopic evaluation of swallowing (FEES). Pharyngeal residue is a clinical sign of potential prandial aspiration making an accurate description of its severity an important but difficult challenge. A reliable, validated, and generalizable pharyngeal residue severity rating scale for FEES would be beneficial. A systematic review of the published English language literature since 1995 was conducted to determine the quality of existing pharyngeal residue severity rating scales based on FEES. Databases were searched using controlled vocabulary words and synonymous free text words for topics of interest (deglutition disorders, pharyngeal residue, endoscopy, videofluoroscopy, fiberoptic technology, aspiration, etc.) and outcomes of interest (scores, scales, grades, tests, FEES, etc.). Search strategies were adjusted for syntax appropriate for each database/platform. Data sources included MEDLINE (OvidSP 1946-April Week 3 2015), Embase (OvidSP 1974-2015 April 20), Scopus (Elsevier), and the unindexed material in PubMed (NLM/NIH) were searched for relevant articles. Supplementary efforts to identify studies included checking reference lists of articles retrieved. Scales were compared using qualitative properties (sample size, severity definitions, number of raters, and raters' experience and training) and psychometric analyses (randomization, intra- and inter-rater reliability, and construct validity). Seven articles describing pharyngeal residue severity rating scales met inclusion criteria. Six of seven scales had insufficient data to support their use as evidenced by methodological weaknesses with both qualitative properties and psychometric analyses. There is a need for qualitative and psychometrically reliable, validated, and generalizable pharyngeal residue severity rating scales that are anatomically specific, image-based, and easily learned by both novice and experienced clinicians. Only the Yale Pharyngeal Residue Severity Rating Scale, an anatomically defined and image-based tool, met all qualitative and psychometric criteria necessary for a valid, reliable, and generalizable vallecula and pyriform sinus severity rating scale based on FEES. [ABSTRACT FROM AUTHOR]
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- 2016
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29. Evaluation of swallowing function in patients with oropharyngeal secretions
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Shinya Mikushi, Taiki Yamaguchi, and Takao Ayuse
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Larynx ,Male ,Saliva ,oropharyngeal secretion ,Laryngeal vestibule ,Swallowing ,stomatognathic system ,otorhinolaryngologic diseases ,microaspiration ,Medicine ,Humans ,Pharyngeal Residue ,General Dentistry ,swallowing function ,Aged ,Retrospective Studies ,Aged, 80 and over ,saliva ,business.industry ,Pharynx ,Hyoid bone ,Anatomy ,Original Articles ,Middle Aged ,Dysphagia ,Deglutition ,lcsh:RK1-715 ,stomatognathic diseases ,Oropharyngeal Neoplasms ,medicine.anatomical_structure ,lcsh:Dentistry ,Original Article ,Female ,medicine.symptom ,business ,videofluorography ,videoendoscopy - Abstract
Background Several studies have reported a strong association between the presence of oropharyngeal secretions in the laryngeal vestibule and the likelihood of aspiration of food or liquid. However, no previous studies have evaluated the accumulation of saliva and swallowing dynamics. Objective The objective of this study was to examine the factors related to decreased function that result in saliva accumulation based on images from videofluoroscopic examination of swallowing (VF) performed on the same day as videoendoscopic examination of swallowing (VE). Methods This retrospective study investigated 47 patients with dysphagia who underwent VF and VE on the same day. Saliva accumulation in the pharynx was assessed on VE and classified by the Murray secretion scale. Pharyngeal residue was assessed on VF. In addition, displacement of the hyoid bone and larynx on swallowing and the opening size of the esophageal orifice were measured, and contact between the base of the tongue and the posterior pharyngeal wall was examined on VF. Results Moderate correlations were found between saliva accumulation and perpendicular displacement of the larynx and upper esophageal sphincter opening. The percentage of patients showing contact between the base of the tongue and the posterior pharyngeal wall was significantly greater in those with a saliva accumulation score of 0 or 1. Conclusion Less laryngeal elevation and upper esophageal sphincter opening and absence of contact between the base of the tongue and the posterior pharyngeal wall when swallowing tended to result in accumulation of saliva in the pharynx.
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- 2019
30. Validity and reliability of the Italian translation of the Yale Pharyngeal Residue Severity Rating Scale.
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Nordio S, Maistrello L, D'Imperio D, Favaretto N, Dellai A, Montino S, Agostinelli A, Ramacciotti G, Gheller F, Berta G, Koch I, Zanoletti E, Battel I, and Cazzador D
- Subjects
- Humans, Reproducibility of Results, Deglutition, Social Group, Quality of Life, Translations
- Abstract
Objective: In the dysphagic patient, pharyngeal residues (PR) are associated with aspiration and poor quality of life. The assessment of PR using validated scales during flexible endoscopic evaluation of swallowing (FEES) is crucial for rehabilitation. This study aims to validate and test the reliability of the Italian version of the Yale Pharyngeal Residue Severity Rating Scale (IT-YPRSRS). The effects of training and experience in FEES on the scale were also determined., Methods: The original YPRSRS was translated into Italian according to standardised guidelines. Thirty FEES images were selected after consensus and proposed to 22 naive raters who were asked to assess the severity of PR in each image. Raters were divided into two subgroups by years of experience at FEES, and randomly by training. Construct validity, inter-rater, and intra-rater reliability were assessed by kappa statistics., Results: IT-YPRSRS showed substantial to almost perfect agreement (kappa > 0.75) in validity and reliability for both the overall sample (660 ratings), and valleculae/pyriform sinus sites (330 ratings each). No significant differences emerged between groups considering years of experience, and variable differences were observed by training., Conclusions: The IT-YPRSRS demonstrated excellent validity and reliability in identifying location and severity of PR., (Copyright © 2023 Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy.)
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- 2023
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31. The Yale Pharyngeal Residue Severity Rating Scale: An Anatomically Defined and Image-Based Tool.
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Neubauer, Paul, Rademaker, Alfred, Leder, Steven, Neubauer, Paul D, Rademaker, Alfred W, and Leder, Steven B
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COMPARATIVE studies ,DEGLUTITION disorders ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,RESEARCH evaluation ,EVALUATION research ,RANDOMIZED controlled trials ,SEVERITY of illness index - Abstract
The Yale Pharyngeal Residue Severity Rating Scale was developed, standardized, and validated to provide reliable, anatomically defined, and image-based assessment of post-swallow pharyngeal residue severity as observed during fiberoptic endoscopic evaluation of swallowing (FEES). It is a five-point ordinal rating scale based on residue location (vallecula and pyriform sinus) and amount (none, trace, mild, moderate, and severe). Two expert judges reviewed a total of 261 FEES evaluations and selected a no residue exemplar and three exemplars each of trace, mild, moderate, and severe vallecula and pyriform sinus residue. Hard-copy color images of the no residue, 12 vallecula, and 12 pyriform sinus exemplars were randomized by residue location for hierarchical categorization by 20 raters with a mean of 8.3 years of experience (range 2-27 years) performing and interpreting FEES. Severity ratings for all images were performed by the same 20 raters, 2 weeks apart, and with the order of image presentations randomized. Intra-rater test-retest reliability, inter-rater reliability, and construct validity were determined by pooled multi-category multi-rater kappa statistics. Residue ratings were excellent for intra-rater reliability for vallecula (kappa = 0.957 ± 0.014) and pyriform sinus (kappa = 0.854 ± 0.021); very good to excellent for inter-rater reliability for vallecula (kappa = 0.868 ± 0.011) and pyriform sinus (kappa = 0.751 ± 0.011); and excellent for validity for vallecula (kappa = 0.951 ± 0.014) and pyriform sinus (kappa = 0.908 ± 0.017). Clinical uses include accurate classification of vallecula and pyriform sinus residue severity patterns as none, trace, mild, moderate, or severe for diagnostic purposes, determination of functional therapeutic change, and precise dissemination of shared information. Scientific uses include tracking outcome measures, demonstrating efficacy of interventions to reduce pharyngeal residue, investigating morbidity and mortality in relation to pharyngeal residue severity, and improving training and accuracy of FEES interpretation by students and clinicians. The Yale Pharyngeal Residue Severity Rating Scale is a reliable, validated, anatomically defined, and image-based tool to determine residue location and severity based on FEES. [ABSTRACT FROM AUTHOR]
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- 2015
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32. Which Physiological Swallowing Parameters Change with Healthy Aging?
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Catriona M. Steele, Renata Mancopes, Pooja Gandhi, and Sana Smaoui
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medicine.medical_specialty ,presbyphagia ,business.industry ,digestive, oral, and skin physiology ,aging ,Audiology ,Article ,Constriction ,Deglutition ,Pharyngeal area ,Swallowing ,Presbyphagia ,stomatognathic system ,Duration (music) ,kinematics ,medicine ,sense organs ,videofluoroscopy ,Healthy aging ,Bolus (digestion) ,Pharyngeal Residue ,business ,swallowing - Abstract
Research suggests there are age-related changes in swallowing that do not constitute impairment (“presbyphagia”). The goal of this study was to explore the influence of age on quantitative measures of healthy swallowing by controlling for the effects of sex and sip volume in order to determine the specific characteristics of presbyphagia. Videofluoroscopy recordings of thin liquid swallows from 76 healthy adults (38 male), aged 21-82 were analysed. Blinded duplicate ratings of swallowing safety, efficiency, kinematics, and timing were made using the ASPEKT method. Hierarchical regression models were used to determine the effects of age, sex, and sip-volume on swallowing. There were no age-related changes in sip volume, number of swallows per bolus, frequency or severity of penetration-aspiration, duration of the hyoid-burst (HYB)-to-upper-esophageal-sphincter (UES) opening interval, time-to-laryngeal-vestibule-closure (LVC), peak hyoid position, hyoid speed, or pharyngeal residue. Significant changes seen with increasing age included: longer swallow reaction time, UES opening duration and LVC duration; larger pharyngeal area at rest and maximum constriction; and wider UES diameter. Male participants had larger sip volume and pharyngeal area at rest. Larger sip volumes were associated with multiple swallows per bolus and shorter hyoid-burst-to-UES opening intervals. These results help to define presbyphagic changes in swallowing that can be expected in healthy older adults up to 80 years of age, and distinguish them from changes that represent impairment. Certain parameters showed changes that were opposite in direction to changes that are usually considered to reflect impairment: longer UES opening, longer LVC duration and wider UES opening. These changes may reflect possible compensations for slower bolus transit. Further research is needed to determine the points along the age continuum where observed age-related changes in swallowing begin to emerge.
- Published
- 2021
33. Long-term swallowing outcomes of radiotherapy and transoral laser microsurgery for T1 glottic cancer treatment
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Emre Sahin, Kerem Öztürk, Serdar Akyildiz, Duygu Durusoy, Mustafa Esassolak, Sibel Eyigör, Goksel Turhal, Ozlem Ozkaya Akagunduz, and Ege Üniversitesi
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Male ,medicine.medical_specialty ,Glottis ,Microsurgery ,medicine.medical_treatment ,Piriform sinus ,Swallowing ,Throat ,otorhinolaryngologic diseases ,Medicine ,Humans ,Transoral laser microsurgery ,Pharyngeal Residue ,Laryngeal Neoplasms ,Neoplasm Staging ,Radiotherapy ,business.industry ,digestive, oral, and skin physiology ,Carbon Dioxide ,Middle Aged ,medicine.disease ,Dysphagia ,Combined Modality Therapy ,Surgery ,Radiation therapy ,medicine.anatomical_structure ,Otorhinolaryngology ,[No Keyword] ,Lasers, Gas ,Female ,Esophagoscopy ,Laser Therapy ,medicine.symptom ,business ,Choking ,Deglutition Disorders - Abstract
Introduction Both CO2 transoral laser microsurgery (CO2 TOLMS) and radiotherapy (RT) are standard of care in early glottic carcinoma. However, previous studies focus on voice outcomes rather than swallowing outcomes. This study aimed to compare the late post-treatment effects of CO2 TOLMS and RT treatment on swallowing function in T1 glottic carcinoma. Methods Forty patients (20 CO2 TOLMS and 20 RT) with T1 glottic cancer between May 2015 and January 2019 were included. Certain types of foods triggering dysphagia, any difficulties in bolus control, need to clean the throat, the sensation of lumping in the throat, choking, cough and xerostomia were questioned. Also, functional oral intake scale (FOIS), functional outcome swallowing scale (FOSS), Eating Assessment Tool-10 test (EAT-10) and flexible fiberoptic endoscopic examination of swallowing (FEES) findings were assessed. Results CO2 TOLMS patients performed significantly better than the RT group regarding penetration and aspiration with 10 and 20 mL water according to the Penetration and Aspiration Scale (P < .05). The mean EAT-10 Score was found 0 in the CO2 TOLMS group, and 3.20 +/- 3.24 in the RT group (P < .05) (lower score indicates a better outcome). According to the Yale Pharyngeal Residue Severity Scale for vallecula, there was no statistically significant difference in vallecular residue between the groups (P > .05). A significantly lesser residue in piriform sinus was detected in the CO2 TOLMS group compared to the RT group with 5 mL and 10 mL water, 5 mL and 20 mL honey consistency food and yogurt according to Yale Pharyngeal Residue Severity Scale (P < .05). Conclusion It is suggested that in the long term, CO2 TOLMS is more advantageous regarding swallowing function in the treatment of T1 glottic cancer.
- Published
- 2021
34. Effects of Pharyngeal Electrical Stimulation on Swallow Timings, Clearance and Safety in Post-Stroke Dysphagia: Analysis from the Swallowing Treatment Using Electrical Pharyngeal Stimulation (STEPS) Trial
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Shaheen Hamdy, Jacqueline K Benfield, Emilia Michou, Lisa F Everton, Philip M.W. Bath, and Mezzapesa, Domenico Maria
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Article Subject ,Clinical Neurology ,Stimulation ,ASPIRATION ,behavioral disciplines and activities ,MECHANISMS ,030507 speech-language pathology & audiology ,03 medical and health sciences ,0302 clinical medicine ,Swallowing ,Post-hoc analysis ,Medicine ,Pharyngeal Residue ,RC346-429 ,Stroke ,Science & Technology ,business.industry ,medicine.disease ,Dysphagia ,Peripheral Vascular Disease ,Anesthesia ,Post stroke ,Cardiovascular System & Cardiology ,Neurology (clinical) ,Neurology. Diseases of the nervous system ,medicine.symptom ,Bolus (digestion) ,0305 other medical science ,business ,Life Sciences & Biomedicine ,030217 neurology & neurosurgery ,STROKE ,Research Article - Abstract
Swallowing impairment (dysphagia) post-stroke results in poorer outcomes. Pharyngeal electrical stimulation (PES) is a potential treatment for post-stroke dysphagia. In a post hoc analysis, we investigated PES using videofluoroscopy swallow studies (VFSS) from the STEPS trial incorporating multiple measures of safety (penetration aspiration scale-PAS), speed and duration (timing), and efficiency (clearance), as opposed to the original trial which only measured PAS scores. 81 randomised participants (PES ( N = 43 ) versus sham ( N = 38 )) were analysed at baseline and 2 weeks. Participants swallowed up to 6 × 5 ml and 1 × 50 ml of thin liquid barium at 40% w / v , images at ≥25 fps. Based on PAS, the 5 ml mode bolus (most frequently occurring PAS from 6 × 5 ml ) and the worst 50 ml bolus were chosen for further analysis. Eight timing measures were performed, including stage transition duration (STD) and pharyngeal transit time (PTT). Clearance measures comprised oral and pharyngeal residue and swallows to clear. Comparisons of change of scoring outcomes between PES and sham were done at 2 weeks. Wilcoxon Signed Ranks Test was also used to evaluate longitudinal changes from both groups’ combined results at two weeks. Between-group analysis showed no statistically significant differences. Issues with suboptimal image quality and frame rate acquisition affected final numbers. At two weeks, both groups demonstrated a significant improvement in most safety scores (PAS) and STD, possibly due to spontaneous recovery or a combination of spontaneous recovery and swallowing treatment and usual care. A nonsignificant trend for improvement was seen in other timing measures, including PTT. This study, which conducted additional measurements of kinematic and residue analysis on the STEPS data did not detect “missed” improvements in swallowing function that the PAS is not designed to measure. However, more studies with greater numbers are required.
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- 2021
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35. Successful Treatment with the Chin-down Maneuver of Dysphagia Secondary to Descending Necrotizing Mediastinitis: A Case Study
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Minoru Toyokura, Ayaka Sugimoto, Yuri Isaji, Takashi Kasahara, Yoshihisa Masakado, Yuji Koyama, and Michi Tochikura
- Subjects
medicine.medical_specialty ,chin-down postural technique ,business.industry ,dysphagia ,Infrahyoid muscles ,descending necrotizing mediastinitis ,Case Report ,deglutition disorders ,General Medicine ,medicine.disease ,Dysphagia ,Mediastinitis ,Surgery ,medicine.anatomical_structure ,Swallowing ,Sternohyoid muscle ,Geniohyoid muscle ,medicine ,deglutition ,medicine.symptom ,Pharyngeal Residue ,business ,Muscle contraction - Abstract
Background: Descending necrotizing mediastinitis is a potentially fatal polymicrobial infection that often leads to dysphagia after treatment. Such dysphagia is likely the result of fibrosis and scarring from inflammatory changes in the fascial space. A case is presented in which the mechanism of dysphagia was verified using two-dimensional analysis of the muscle lengths of the suprahyoid and infrahyoid muscles. Case: A 57-year-old woman presented with a hyoid and laryngeal movement disorder with pharyngeal residue secondary to descending necrotizing mediastinitis. To treat this disorder, the chin-down maneuver was performed, and it immediately improved hyoid and laryngeal elevation and reduced pharyngeal residue at the epiglottic valleculae and pyriform sinus. Analysis of the mechanism of these improvements revealed that combined head and neck flexion, compared with neck flexion, decreased the distance between the origin and insertion (DOI) of the sternohyoid muscle (SM) and increased the muscle contraction rate and the maximum contraction duration of the geniohyoid muscle (GM) during swallowing. Discussion: In the present case, the patient had restrictions in extension of the SM that applied resistance to GM contraction. Compensation of this condition was achieved by combined head and neck flexion, which decreased the DOI of the SM, thereby improving the contractile function of the GM.
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- 2020
36. Dysphagia in duchenne muscular dystrophy versus myotonic dystrophy type 1.
- Author
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Umemoto, George, Furuya, Hirokazu, Kitashima, Akio, Sakai, Mitsuaki, Arahata, Hajime, and Kikuta, Toshihiro
- Abstract
Introduction: In this study we aimed to demonstrate the distinctive features of dysphagia in patients with myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD). Methods: Diet-type score (DTS) and maximum tongue pressure (MTP) were measured in 20 DM1 and 24 DMD patients; all patients were also examined by videofluoroscopy (VF). We used VF to measure the range of hyoid bone excursion (RHBE) during pharyngeal transit time and the area of pharyngeal residue (APR) after the first swallow. Results: RHBE and APR values for DM1 patients were significantly greater than those for DMD patients. DTS and MTP did not differ between patients. A significant correlation was observed between DTS, MTP, and RHBE in DMD patients, but not in DM1 patients. Conclusions: Our findings reveal the differences in the distinctive features of dysphagia in DM1 and DMD. Adjustments in the diet of DMD patients in accordance with swallowing ability could be useful. Muscle Nerve 46: 490-495, 2012 [ABSTRACT FROM AUTHOR]
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- 2012
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37. Rethinking Residue: Determining the Perceptual Continuum of Residue on FEES to Enable Better Measurement
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Pisegna, Jessica M., Kaneoka, Asako, Leonard, Rebecca, and Langmore, Susan E.
- Published
- 2017
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38. Quantitative Assessment of Swallowing Dysfunction in Patients with Spinal and Bulbar Muscular Atrophy
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Keisuke Suzuki, Tomonori Inagaki, Atsushi Hashizume, Yasuhiro Hijikata, Masahisa Katsuno, Shinichiro Yamada, Gen Sobue, and Haruhiko Banno
- Subjects
Larynx ,Adult ,Male ,Bulbo-Spinal Atrophy, X-Linked ,Aspiration pneumonia ,Pneumonia, Aspiration ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,chemistry.chemical_compound ,pharyngeal barium residue ,0302 clinical medicine ,Swallowing ,stomatognathic system ,swallowing dysfunction ,Internal Medicine ,medicine ,otorhinolaryngologic diseases ,Fluoroscopy ,Humans ,Pharyngeal Residue ,Aged ,Aged, 80 and over ,medicine.diagnostic_test ,spinal and bulbar muscular atrophy ,business.industry ,digestive, oral, and skin physiology ,General Medicine ,Anatomy ,Middle Aged ,medicine.disease ,Dysphagia ,Deglutition ,Barium sulfate ,Spinal and bulbar muscular atrophy ,medicine.anatomical_structure ,chemistry ,Anesthesia ,motor neuron disease ,videofluoroscopic swallowing study ,Original Article ,Female ,medicine.symptom ,Barium Sulfate ,business ,Deglutition Disorders ,030217 neurology & neurosurgery - Abstract
Objective This study aimed to evaluate swallowing dysfunction in patients with spinal and bulbar muscular atrophy and to identify the most appropriate method of assessing swallowing dysfunction using a videofluoroscopic swallowing study. Methods In the videofluoroscopic swallowing study, patients were instructed to swallow 3 mL of 40% weight/volume barium sulfate twice, and the pharyngeal residue was measured. We used three different methods to quantify the pharyngeal barium residue and an eight-point scale to evaluate the laryngeal penetration leading to aspiration pneumoniae. Patients We assessed 111 patients with spinal and bulbar muscular atrophy who weren't undergoing disease-specific treatment. Results Our results showed that the pharyngeal barium residue after initial swallowing correlated better with the bulbar-related functional rating scales than that after multiple deglutition. This correlation was vague when the data from patients whose barium residue was >50% were eliminated. In addition, evaluating the pharyngeal residue after initial swallowing proved to be the most sensitive method with regard to laryngeal penetration. Conclusion This study showed that the pharyngeal barium residue after initial swallowing was the most appropriate parameter for quantitatively assessing the degree of dysphagia using a videofluoroscopic swallowing study and suggests that this method may predict laryngeal penetration and aspiration in patients with spinal and bulbar muscular atrophy.
- Published
- 2017
39. Relation between acoustic analysis of swallowing and the presence of pharyngeal residue and penetration/aspiration in resistant hypertensive patients with obstructive sleep apnea
- Author
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Mariana Pinheiro Brendim, Thalyta Georgia Vieira Borges, Carla Rocha Muniz, Flavia Rodrigues Ferreira, and Elizabeth Silaid Muxfeldt
- Subjects
Population ,P1-1091 ,Polysomnography ,Swallowing ,Statistical significance ,medicine ,otorhinolaryngologic diseases ,Statistical analysis ,Pharyngeal Residue ,education ,Philology. Linguistics ,General Environmental Science ,education.field_of_study ,Sleep Apnea, Obstructive ,medicine.diagnostic_test ,business.industry ,digestive, oral, and skin physiology ,General Medicine ,Auscultation ,medicine.disease ,Deglutition ,Obstructive sleep apnea ,Otorhinolaryngology ,RF1-547 ,Anesthesia ,General Earth and Planetary Sciences ,business ,Deglutition Disorders - Abstract
Purpose: to evaluate the relationship between acoustic analysis of swallowing sounds and the presence of pharyngeal residue and penetration/aspiration detected by fiberoptic endoscopic evaluation of swallowing in resistant hypertensive patients with obstructive sleep apnea. Methods: an observational study in which resistant hypertensive individuals diagnosed with obstructive sleep apnea participated through the all-night polysomnography exam. The participants underwent an acoustic analysis of swallowing sounds, using a Doppler sonar and simultaneously a fiberoptic endoscopic evaluation of swallowing. The acoustic parameters analyzed were initial frequency, initial intensity, first peak frequency, second peak frequency, final intensity and swallowing time. Independent samples of t-test and Mann-Whitney test were used for statistical analysis. The level of statistical significance adopted was 5%. Results: eighty five participants with average age of 58.3±6.3 years were evaluated. There was a statistically significant difference between groups with and without pharyngeal residue, in relation to the following parameters of swallowing acoustic signal: initial frequency and intensity, second peak frequency, final intensity and swallowing time. Only 10 milliliters of pudding consistency showed a statistically significant difference in the second peak frequency of the acoustic signal of swallowing between groups with and without penetration/aspiration. Conclusion: a relationship between measurements of swallowing acoustic signal and pharyngeal residue in this population was found, but not between swallowing sounds and penetration/aspiration.
- Published
- 2020
40. 5th ESSD Congress, Swallowing Disorders: From Compensation to Recovery, Barcelona October 1–3, 2015
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- 2016
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41. Quantifying Airway Invasion and Pharyngeal Residue in Patients with Dementia
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Ashwini M. Namasivayam-MacDonald, Luis F. Riquelme, and Rehabilitation Science
- Subjects
Aging ,medicine.medical_specialty ,Health (social science) ,dysphagia ,assessment ,Population ,penetration ,lcsh:Geriatrics ,Gastroenterology ,Article ,030507 speech-language pathology & audiology ,03 medical and health sciences ,0302 clinical medicine ,Swallowing ,stomatognathic system ,Internal medicine ,residue ,medicine ,otorhinolaryngologic diseases ,Dementia ,deglutition ,Pharyngeal Residue ,education ,education.field_of_study ,aspiration ,business.industry ,digestive, oral, and skin physiology ,medicine.disease ,Dysphagia ,Pyriform Sinus ,lcsh:RC952-954.6 ,Relative risk ,Geriatrics and Gerontology ,medicine.symptom ,0305 other medical science ,Airway ,business ,Gerontology ,swallowing ,030217 neurology & neurosurgery ,dementia - Abstract
Previous research has begun to elucidate the physiological impairments associated with dysphagia in patients with dementia, but in order to select the most appropriate targets of intervention we need to better understand consequences of dysphagia. The purpose of this study was to quantify penetration, aspiration, and residue in people with dementia, and confirm if residue was associated with airway invasion on subsequent swallows. Videofluoroscopy clips of sips of thin and extremely thick liquid barium from 58 patients with dementia were retrospectively analyzed. Ratings of swallowing safety, using the Penetration&ndash, Aspiration Scale (PAS), and efficiency, using Normalized Residue Ratio Scale in the valleculae (NRRSv) and pyriform sinuses (NRRSp), were made on all swallows. Over 70% of both thin and extremely thick liquid swallows were found to be safe (PAS <, 3). Results also revealed that residue was generally more common in the valleculae. However, the proportion of thin liquid swallows with significant NRRSp that were unsafe on the subsequent swallow was significantly greater than the proportion of swallows with significant NRRSp that were safe on the subsequent swallow. As such, there was a 2.83 times greater relative risk of penetration&ndash, aspiration in the presence of thin liquid pyriform sinus residue. Future research should determine the impaired physiology causing aspiration and residue in this population.
- Published
- 2019
42. Dysphagia Onset in Older Adults during Unrelated Hospital Admission: Quantitative Videofluoroscopic Measures
- Author
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Jacqui Allen, Marie Jardine, and Anna Miles
- Subjects
Aging ,Pediatrics ,medicine.medical_specialty ,Health (social science) ,dysphagia ,frailty ,lcsh:Geriatrics ,Asymptomatic ,Article ,sarcopenia ,03 medical and health sciences ,0302 clinical medicine ,Presbyphagia ,Swallowing ,medicine ,otorhinolaryngologic diseases ,030212 general & internal medicine ,Pharyngeal Residue ,Polypharmacy ,business.industry ,Retrospective cohort study ,Dysphagia ,lcsh:RC952-954.6 ,Cohort ,older age ,videofluoroscopy ,Geriatrics and Gerontology ,medicine.symptom ,business ,Gerontology ,swallowing ,030217 neurology & neurosurgery ,hospitalization - Abstract
New-onset swallowing difficulties in older patients during unrelated hospital admissions are well recognized and may result in prolonged hospital stay and increased morbidity. Presbyphagia denotes age-related swallowing changes which do not necessarily result in pathological effects. The trajectory from presbyphagia to dysphagia is not well understood. This retrospective observational study compared quantitative videofluoroscopic measures in hospitalized older adults aged 70&ndash, 100 years, reporting new dysphagia symptoms during admission (n = 52), to healthy asymptomatic older (n = 56) and younger adults (n = 43). Significant physiological differences seen in hospitalized older adults but not healthy adults, were elevated pharyngeal area (p <, 0.001) and pharyngeal constriction ratio (p <, 0.001). Significantly increased penetration (p <, 0.001), aspiration (p <, 0.001) and pharyngeal residue (p <, 0.001) were also observed in the hospitalized older cohort. Reasons for onset of new swallow problems during hospitalization are likely multifactorial and complex. Alongside multimorbidity and polypharmacy, a combination of factors during hospitalization, such as fatigue, low levels of alertness, delirium, reduced respiratory support and disuse atrophy, may tip the balance of age-related swallowing adaptations and compensation toward dysfunctional swallowing. To optimize swallowing assessment and management for our aging population, care must be taken not to oversimplify dysphagia complaints as a characteristic of aging.
- Published
- 2018
43. Presentation of oropharyngeal dysphagia and rehabilitative intervention following esophagectomy: a systematic review
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Asako Kaneoka, S Yang, Rumi Ueha, Takaharu Nito, Nobuhiko Haga, Yasuyuki Seto, Hiroharu Yamashita, and Haruhi Inokuchi
- Subjects
Male ,medicine.medical_specialty ,Esophageal Neoplasms ,medicine.medical_treatment ,Psychological intervention ,Review Article ,Systematic Reviews and Meta-analysis ,rehabilitation ,03 medical and health sciences ,0302 clinical medicine ,Swallowing ,stomatognathic system ,Intervention (counseling) ,medicine ,otorhinolaryngologic diseases ,Humans ,Pharyngeal Residue ,business.industry ,digestive, oral, and skin physiology ,Gastroenterology ,deglutition disorders ,General Medicine ,medicine.disease ,Deglutition ,Esophagectomy ,Pneumonia ,Treatment Outcome ,030220 oncology & carcinogenesis ,Physical therapy ,030211 gastroenterology & hepatology ,Female ,Presentation (obstetrics) ,medicine.symptom ,business ,Oropharyngeal dysphagia - Abstract
Summary No study has systematically reviewed the evidence on presentation of oropharyngeal dysphagia and swallowing rehabilitation following esophagectomy. The purposes of this systematic review are to 1) qualitatively synthesize the current findings on oropharyngeal swallowing abnormalities identified by instrumental swallowing evaluations, 2) describe the reported health-related outcomes in relation to swallowing abnormality following esophagectomy, and 3) examine the efficacy of reported rehabilitative interventions for oropharyngeal dysphagia in patients who underwent esophagectomy. Publications were searched using five electronic databases. No language or publication date restrictions were imposed. Two authors performed a blind review for published or unpublished studies that reported swallowing biomechanics and dysphagic symptoms using instrumental evaluation of swallowing, specifically the videofluoroscopic swallowing study and fiberoptic endoscopic evaluation of swallowing, and/or health-related outcomes in relation to swallowing abnormalities, and/or therapeutic interventions for oropharyngeal dysphagia following esophagectomy. Twelve studies out of 2,193 studies including 458 patients met the inclusion criteria. Reported abnormal swallowing biomechanics included vocal fold immobility, delayed onset of swallowing, reduced hyolaryngeal elevation, and reduced opening of the upper esophageal sphincter. Aspiration (0–81%) and pharyngeal residue (22–100%) were prevalent. Those abnormal swallowing biomechanics and swallowing symptoms were commonly reported following both transhiatal and transthoracic esophagectomy. Pneumonia presented in 5–25% of the study patients. One quasi-experimental study examined the effectiveness of swallowing exercises for postoperative oropharyngeal dysphagia; three case series reported a benefit of the chin-tuck maneuver in reducing aspiration and residue. This review revealed distinct swallowing impairments and increased pneumonia risks following esophagectomy. This review also found that evidence on the efficacy of therapeutic interventions was limited. Future studies are warranted to develop effective rehabilitative interventions for postesophagectomy patients with oropharyngeal dysphagia.
- Published
- 2018
44. Oral support for patients with severe motor and intellectual disabilities.
- Author
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Nakamura T, Kita Y, Fujimoto J, Ayuzawa K, and Ozawa H
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Deglutition, Female, Humans, Hyoid Bone, Male, Middle Aged, Young Adult, Deglutition Disorders etiology, Intellectual Disability
- Abstract
Background: Oral support during feeding was clinically provided to patients with severe motor and intellectual disabilities (SMID) for the prevention of dysphasia. The present study investigated the advantages of oral support anatomically and functionally., Methods: A videofluoroscopic swallowing study was conducted on nine patients with SMID (age = 5-41 years; mean age = 15.0; four males, five females) and 24 healthy adults (age = 26-67 years; mean age = 44.3; 16 males, eight females). The movements of the hyoid bone and mandible during pharyngeal swallowing were tracked, and the pharyngeal residues were evaluated. The temporal and spatial features of the movements were compared between patients with and without oral support as well as healthy adults., Results: The mandible moved downward earlier and showed larger displacement in the patients with SMID. The patients also had insufficient anterior displacement of the hyoid, which was associated with the pharyngeal residue. This displacement was enhanced, and the pharyngeal residue decreased with oral support., Conclusions: Oral support to hold the mandible successfully improved hyoid excursion and reduced pharyngeal residue during swallowing, which is a simple and reliable strategy for the prevention of dysphasia in patients with SMID., (© 2021 Japan Pediatric Society.)
- Published
- 2022
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45. Effects of Tablet Size and Head Posture on Drug Swallowing: A Preliminary Examination Using Endoscopy in Healthy Subjects.
- Author
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Sugiyama S, Iida T, Morimoto Y, Yamazaki Y, Mikuzuki L, and Hayashi M
- Subjects
- Adult, Endoscopy, Female, Healthy Volunteers, Humans, Male, Deglutition, Posture, Tablets
- Abstract
Tablet size and head posture have been reported to affect swallowing of medications, but no previous studies have evaluated their effects in detail. Our aim was to investigate for the first time the effect of tablet size and head posture on drug swallowing by endoscopic evaluation in healthy subjects. Round tablets (7 , 10 , 12, and 14 mm in diameter) were swallowed by 15 healthy adults with an endoscope inserted in the neutral, head flex-ion, and head extension positions. Evaluation of swallowing difficulty using a numeric rating scale (NRS), presence or absence of pharyngeal residue and its location, and tablet oral transit time (TOTT) were recorded. In the neutral position, the NRS score was higher with the 14 mm tablets than with the 7 mm tablets. The TOTT with the 7 mm tablets was significantly shorter in the head extension than in the neutral position. Swallowing difficulty increased when the tablet diameter was more than 7 mm. Residues were found in the epi-glottis, pyriform sinus, and tongue base. These findings suggest that head extension shortens the TOTT and assists oral-pharyngeal transport., Competing Interests: No potential conflict of interest relevant to this article was reported.
- Published
- 2021
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46. Relationship between swallowing-related quality of life and fiberoptic endoscopic evaluation of swallowing in patients who underwent open partial horizontal laryngectomy
- Author
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Giuseppe Rizzotto, Giovanni Succo, Federico Ambrogi, Antonio Schindler, Andy Bertolin, Nicole Pizzorni, Erika Crosetti, and Marco Fantini
- Subjects
Adult ,Male ,Quality of life ,medicine.medical_specialty ,FEES ,Open partial laryngectomy ,Laryngectomy ,Statistics, Nonparametric ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Swallowing ,otorhinolaryngologic diseases ,Humans ,Medicine ,Postoperative Period ,030223 otorhinolaryngology ,MD Anderson Dysphagia Inventory ,Pharyngeal Residue ,Aged ,business.industry ,Otorhinolaryngology2734 Pathology and Forensic Medicine ,Endoscopy ,General Medicine ,Middle Aged ,MDADI ,Dysphagia ,Deglutition ,Surgery ,Otorhinolaryngology ,Head and Neck Neoplasms ,030220 oncology & carcinogenesis ,Mann–Whitney U test ,Female ,medicine.symptom ,Deglutition Disorders ,Airway ,business - Abstract
Several studies have previously analyzed the relationship between QOL and signs of dysphagia in patients treated for head and neck cancer and have reported heterogeneous findings. To the best of our knowledge, no study has previously investigated this relationship among patients who underwent open partial horizontal laryngectomy (OPHL). The aim of the study is to determine if patient-reported swallowing-related QOL can discriminate between safe and unsafe swallowing in OPHL patients. 92 type I, type II, and type III OPHL patients at least 6 months postoperatively were recruited. Fiberoptic endoscopic evaluation of swallowing (FEES) was conducted using liquids, semisolids, and solids. FEES recordings were assessed through the penetration–aspiration scale, the pooling score and the dysphagia outcome and severity scale. All patients completed the MD Anderson dysphagia inventory (MDADI). Kruskal–Wallis test and post-hoc Mann Whitney U test were performed to compare MDADI scores among different level of airway invasion, post-swallow pharyngeal residue’s degree and overall dysphagia severity. ROC curves were generated to determine diagnostic accuracy of the MDADI. Statistically significant differences in MDADI scores were found between level of airway invasion with semisolids and solids, degree of pharyngeal residue with solids, and severity of dysphagia. MDADI showed significant diagnostic accuracy only in the detection of moderate/severe pharyngeal residue and severe dysphagia; however, sensitivity and specificity were low. Investigating patients’ perception of swallowing impairment and swallowing-related QOL is not sufficient to discriminate safe and unsafe swallowing in OPHL patients.
- Published
- 2018
47. Comments on Selected Recent Dysphagia Literature
- Author
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Sasaki, Clarence T. and Leder, Steven B.
- Published
- 2013
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48. Associação entre presença de resíduos faríngeos e escape oral posterior e a ocorrência de penetração e aspiração no Acidente Vascular Encefálico
- Author
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Roberta Gonçalves da Silva, Priscila Watson Ribeiro, Adriana Gomes Jorge, Roberto Oliveira Dantas, Fernanda Matias Peres, Rarissa Rúbia Dallaqua dos Santos, André Vinicius Marcondes Natel Sales, Paula Cristina Cola, Universidade Estadual Paulista (Unesp), Hospital Estadual Bauru, and Universidade de São Paulo (USP)
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cross-sectional study ,Language and Linguistics ,Avaliação ,Acidente vascular cerebral ,Speech and Hearing ,Spillage ,Transtornos de deglutição ,lcsh:P1-1091 ,Swallowing ,medicine ,Humans ,Pharyngeal Residue ,Evaluation ,Aged ,Retrospective Studies ,Aged, 80 and over ,Microscopy, Video ,business.industry ,Respiratory Aspiration ,Retrospective cohort study ,Middle Aged ,lcsh:Otorhinolaryngology ,lcsh:RF1-547 ,Dysphagia ,Deglutition disorders ,Aspiração respiratória ,Biomechanical Phenomena ,Surgery ,lcsh:Philology. Linguistics ,Stroke ,Cross-Sectional Studies ,Otorhinolaryngology ,Fluoroscopy ,Respiratory aspiration ,Female ,medicine.symptom ,Deglutition Disorders ,business ,Oropharyngeal dysphagia - Abstract
Made available in DSpace on 2015-02-02T12:39:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-06-01Bitstream added on 2015-02-02T13:07:56Z : No. of bitstreams: 1 S2317-17822014000300231.pdf: 109484 bytes, checksum: 0d8e9ae7ee22bcededf15d9543eb845e (MD5) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) OBJETIVO: Este estudo teve por objetivo verificar a associação entre a ocorrência de escape oral posterior e a presença de resíduos faríngeos com penetração laríngea e/ou aspiração laringotraqueal no acidente vascular encefálico (AVE). MÉTODOS: Estudo clínico transversal, retrospectivo e multicêntrico. Foram incluídos neste estudo 63 exames videofluoroscópicos de indivíduos pós-AVE isquêmico e disfagia orofaríngea do banco de dados dos serviços de três centros públicos de referência no atendimento do indivíduo disfágico, sendo 43 do gênero masculino e 20 do gênero feminino, faixa etária variando de 40 a 90 anos. Estes foram divididos em dois grupos. O Grupo I foi composto por exames de 35 indivíduos com presença de penetração e/ou aspiração laringotraqueal e o Grupo II, por exames de 28 indivíduos com ausência de penetração e/ou aspiração. Foram analisados exames de videofluoroscopia da deglutição para dividir os grupos e observou-se a presença de escape posterior e resíduos faríngeos. RESULTADOS: Não houve associação entre os grupos com o escape oral posterior (χ2=1,65; p=0,30; φ2=0,02), porém houve associação entre resíduos faríngeos (χ2=12,86; p=0,003; φ2=0,20) e os grupos. CONCLUSÃO: Diante dos resultados obtidos, concluiu-se que há associação entre a presença de resíduos faríngeos com a ocorrência de penetração com aspiração laringotraqueal em indivíduos pós-AVE. PURPOSE: This study aimed at showing association between the posterior oral spillage and pharyngeal residue with tracheal aspiration and/or laryngeal penetration in stroke. METHODS: Clinical cross-sectional retrospective multicenter study. The study included 63 videofluoroscopic tests of post-ischemic stroke individuals and oropharyngeal dysphagia data of the three reference centers providing care for patients with dysphagia (43 men and 20 women; age range: from 40 to 90 years). These individuals were divided into two groups. Group I consisted of 35 participants with the presence of penetration and/or laryngotracheal aspiration, and Group II consisted of 28 individuals with no penetration and/or aspiration. Videofluoroscopic swallowing test results were analyzed to divide the groups, and the presence of posterior oral spillage and pharyngeal residue was observed. RESULTS: No association was found between the groups with posterior oral spillage (χ2=1.65; p=0.30; φ2=0.02), but there was statistical difference for the association between pharyngeal residue (χ2=12.86; p=0.003; φ2=0.20) and the groups. CONCLUSION: There is an association between pharyngeal residue and penetration with tracheal aspiration in post-stroke individuals.. Universidade Estadual Paulista Júlio de Mesquita Filho Universidade Estadual Paulista Júlio de Mesquita Filho School of Medicine of Botucatu Hospital Estadual Bauru Universidade de São Paulo School of Medicine of Ribeirão Preto Universidade Estadual Paulista Júlio de Mesquita Filho Speech Language Pathology and Audiology Department Universidade Estadual Paulista Júlio de Mesquita Filho Universidade Estadual Paulista Júlio de Mesquita Filho School of Medicine of Botucatu Universidade Estadual Paulista Júlio de Mesquita Filho Speech Language Pathology and Audiology Department
- Published
- 2014
49. A computational fluid dynamics simulation of liquid swallowing by impaired pharyngeal motion: bolus pathway and pharyngeal residue.
- Author
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Ohta J, Ishida S, Kawase T, Katori Y, and Imai Y
- Subjects
- Fluoroscopy methods, Humans, Video Recording methods, Computer Simulation, Deglutition physiology, Deglutition Disorders physiopathology, Hydrodynamics, Pharynx physiopathology, Viscosity
- Abstract
Common practices to improve the ability to swallow include modifying physical properties of foods and changing the posture of patients. Here, we quantified the effects of the viscosity of a liquid bolus and patient posture on the bolus pathway and pharyngeal residue using a computational fluid dynamics simulation. We developed a computational model of an impaired pharyngeal motion with a low pharyngeal pressure and no pharyngeal adaptation. We varied viscosities from 0.002 to 1 Pa·s and postures from -15° to 30° (from nearly vertical to forward leaning). In the absence of pharyngeal adaptation, a honey-like liquid bolus caused pharyngeal residue, particularly in the case of forward-leaning postures. Although the bolus speed was different among viscosities, the final pathway was only slightly different. The shape, location, and tilting of the epiglottis effectively invited a bolus to two lateral pathways, suggesting a high robustness of the swallowing process. NEW & NOTEWORTHY Thickening agents are often used for patients with dysphagia. An increase in bolus viscosity not only reduces the risk of aspiration but also can cause a residual volume in the pharynx. Because information obtained from videofluoroscopic swallowing studies is only two-dimensional, measurement of pharyngeal residue is experimentally difficult. We successfully quantified the three-dimensional bolus pathway and the pharyngeal residual volume using computational modeling and simulation.
- Published
- 2019
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50. Mechanisms explaining the role of viscosity and post-deglutitive pharyngeal residue on in vivo aroma release: A combined experimental and modeling study
- Author
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Ioan Cristian Tréléa, M. Doyennette, C. de Loubens, Isabelle Déléris, Isabelle Souchon, Génie et Microbiologie des Procédés Alimentaires (GMPA), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, and French National Research Agency (ANR)
- Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences ,HEADSPACE ,VOLATILE COMPOUNDS ,MASS-TRANSFER ,01 natural sciences ,RATIO VARIATION METHOD ,Analytical Chemistry ,Viscosity ,chemistry.chemical_compound ,0404 agricultural biotechnology ,Rheology ,In vivo ,AQUEOUS-SOLUTIONS ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Glucose syrup ,Pharyngeal Residue ,Flavor ,Aroma ,Saliva dilution ,HUMAN NASAL CAVITY ,Chromatography ,biology ,Chemistry ,010401 analytical chemistry ,PERSISTENCE ,04 agricultural and veterinary sciences ,General Medicine ,Swallowing ,biology.organism_classification ,040401 food science ,Diacetyl ,Flavour release ,[INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation ,0104 chemical sciences ,PARTITION-COEFFICIENTS ,AIR-FLOW ,FLAVOR RELEASE ,Food Science ,Dynamic modeling - Abstract
The objective of this study was to analyse the viscosity effect of liquid Newtonian products on aroma release, taking human physiological characteristics into account. In vivo release of diacetyl from glucose syrup solutions varying widely in viscosity (from 0.7 to 405 mPa s) was assessed by five panelists using Proton Transfer Reaction Mass Spectrometry (PTR-MS). The physicochemical properties of the solutions and the physiological parameters of subjects were experimentally measured. In parallel, a mechanistic model describing aroma release while eating a liquid food was developed. Model predictions based on the characteristics of the glucose syrup solution were invalidated when compared to in vivo measurements. Therefore, the assumption that the post-deglutitive pharyngeal residue was considerably diluted with saliva was introduced into the model. Under this hypothesis, the model gives a satisfactory prediction of the in vivo data. Thus, relevant properties to be considered for in vivo release were those of product-saliva mixes. (C) 2011 Elsevier Ltd. All rights reserved.
- Published
- 2011
- Full Text
- View/download PDF
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